UY31114A1 - Anticuerpos humanizados contra el globulómero ab(20-42) y sus usos - Google Patents
Anticuerpos humanizados contra el globulómero ab(20-42) y sus usosInfo
- Publication number
- UY31114A1 UY31114A1 UY31114A UY31114A UY31114A1 UY 31114 A1 UY31114 A1 UY 31114A1 UY 31114 A UY31114 A UY 31114A UY 31114 A UY31114 A UY 31114A UY 31114 A1 UY31114 A1 UY 31114A1
- Authority
- UY
- Uruguay
- Prior art keywords
- humanized antibodies
- globulomer
- antibodies against
- alzheimer
- diagnosis
- Prior art date
Links
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Proteínas de unión, y en particular, anticuerpos humanizados que pueden usarse, por ejemplo, en el diagnóstico, el tratamiento y la prevención de la enfermedad de Alzheimer y condiciones relacionadas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94093207P | 2007-05-30 | 2007-05-30 | |
US99035907P | 2007-11-27 | 2007-11-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY31114A1 true UY31114A1 (es) | 2009-01-05 |
Family
ID=39791050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY31114A UY31114A1 (es) | 2007-05-30 | 2008-05-30 | Anticuerpos humanizados contra el globulómero ab(20-42) y sus usos |
Country Status (22)
Country | Link |
---|---|
US (1) | US20090175847A1 (es) |
EP (1) | EP2150563A1 (es) |
JP (1) | JP2010530740A (es) |
KR (1) | KR20100032398A (es) |
CN (1) | CN101827862A (es) |
AR (1) | AR066794A1 (es) |
AU (1) | AU2008260062A1 (es) |
BR (1) | BRPI0812005A2 (es) |
CA (1) | CA2687414A1 (es) |
CL (1) | CL2008001580A1 (es) |
CO (1) | CO6251291A2 (es) |
CR (1) | CR11179A (es) |
DO (1) | DOP2009000269A (es) |
EC (1) | ECSP099833A (es) |
IL (1) | IL202243A0 (es) |
MX (1) | MX2009012950A (es) |
PA (1) | PA8782201A1 (es) |
PE (1) | PE20090329A1 (es) |
RU (1) | RU2009149370A (es) |
TW (1) | TW200914465A (es) |
UY (1) | UY31114A1 (es) |
WO (1) | WO2008150949A1 (es) |
Families Citing this family (46)
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DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
DK1713503T3 (da) * | 2004-02-10 | 2013-11-04 | Univ Colorado Regents | Hæmning af faktor b, den alternative komplemenpathway og dertil relaterede fremgangsmåde |
US20060270922A1 (en) | 2004-07-13 | 2006-11-30 | Brauker James H | Analyte sensor |
US7713574B2 (en) | 2004-07-13 | 2010-05-11 | Dexcom, Inc. | Transcutaneous analyte sensor |
PL2343380T3 (pl) | 2004-11-16 | 2020-03-31 | Humanigen, Inc. | Wymiana kasety dla regionu zmiennego immunoglobuliny |
JP5707024B2 (ja) * | 2005-05-26 | 2015-04-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイトTHE REGENTS OF THE UNIVERSITY OF COLORADO,a body corporate | 外傷性脳損傷、脊髄損傷および関連状態を治療するために補体副経路を阻害する作用剤 |
DK1976877T4 (en) | 2005-11-30 | 2017-01-16 | Abbvie Inc | Monoclonal antibodies to amyloid beta protein and uses thereof |
KR20080090408A (ko) | 2005-11-30 | 2008-10-08 | 아보트 러보러터리즈 | 항-Aβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법 |
RU2551782C2 (ru) * | 2005-12-12 | 2015-05-27 | Ац Иммуне Са | Специфические в отношении амилоида бета (а бета) 1-42 моноклональные антитела, обладающие терапевтическими свойствами |
PL2046833T3 (pl) | 2006-07-14 | 2014-01-31 | Ac Immune Sa | Humanizowane przeciwciało przeciw amyloidowi beta |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
US20100311767A1 (en) | 2007-02-27 | 2010-12-09 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
AU2008251943B2 (en) * | 2007-03-14 | 2013-09-05 | Alexion Pharmaceuticals, Inc. | Humaneered anti-factor B antibody |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
US8048420B2 (en) * | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
US9403902B2 (en) | 2007-10-05 | 2016-08-02 | Ac Immune S.A. | Methods of treating ocular disease associated with amyloid-beta-related pathology using an anti-amyloid-beta antibody |
CA2701790A1 (en) * | 2007-10-05 | 2009-04-16 | Ac Immune S.A. | Use of humanized anti-beta-amyloid antibody in ocular diseases |
BRPI0911758A8 (pt) | 2008-05-09 | 2017-10-10 | Abbott Lab | Anticorpos para receptor de produtos finais de glicação avançada (rage) e utilizações dos mesmos |
EP2453906A4 (en) | 2009-07-02 | 2014-01-15 | Musc Found For Res Dev | METHOD FOR STIMULATING THE LIVER REGENERATION |
US9345661B2 (en) | 2009-07-31 | 2016-05-24 | Genentech, Inc. | Subcutaneous anti-HER2 antibody formulations and uses thereof |
AU2013202020B2 (en) * | 2009-07-31 | 2014-11-27 | F. Hoffmann-La Roche Ag | Subcutaneous anti-HER2 antibody formulation |
AR078161A1 (es) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
TW201121568A (en) | 2009-10-31 | 2011-07-01 | Abbott Lab | Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof |
TW201144437A (en) | 2010-03-03 | 2011-12-16 | Boehringer Ingelheim Int | A-beta binding polypeptides |
RU2012147249A (ru) | 2010-04-07 | 2014-05-20 | Эббви Инк. | TNF-α- СВЯЗЫВАЮЩИЕ БЕЛКИ |
JP2013523182A (ja) * | 2010-04-15 | 2013-06-17 | アボット・ラボラトリーズ | アミロイドベータ結合タンパク質 |
US9320793B2 (en) * | 2010-07-14 | 2016-04-26 | Acumen Pharmaceuticals, Inc. | Method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42 |
JP6081356B2 (ja) | 2010-07-30 | 2017-02-15 | エーシー イミューン エス.エー. | 安全で機能的なヒト化抗βアミロイド抗体 |
CN105348387B (zh) * | 2010-08-14 | 2020-08-25 | Abbvie 公司 | β淀粉样蛋白结合蛋白 |
US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
WO2012075340A2 (en) | 2010-12-01 | 2012-06-07 | Alderbio Holdings Llc | Anti-ngf compositions and use thereof |
US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
CN102516360B (zh) * | 2011-12-08 | 2013-11-06 | 清华大学 | 一种抑制β分泌酶酶切作用的多肽及其应用 |
EP2855529A4 (en) | 2012-05-24 | 2015-12-09 | Alexion Pharma Inc | HUMANIZED ANTI-FACTOR B ANTIBODIES |
BR112015003326A2 (pt) | 2012-08-16 | 2017-07-04 | Ipierian Inc | métodos de tratamento de uma tauopatia |
US9834598B2 (en) * | 2012-10-15 | 2017-12-05 | Medimmune Limited | Antibodies to amyloid beta |
US10400018B2 (en) | 2014-02-14 | 2019-09-03 | Ipierian, Inc. | Tau peptides, anti-tau antibodies, and methods of use thereof |
ES2912729T3 (es) | 2015-11-03 | 2022-05-27 | Janssen Biotech Inc | Formulaciones subcutáneas de anticuerpos anti-CD38 y sus usos |
JP2022541459A (ja) * | 2019-07-16 | 2022-09-26 | サノフイ | アルツハイマー病の処置のための中和抗アミロイドベータ抗体 |
CN117589996A (zh) * | 2022-08-09 | 2024-02-23 | 深圳智源生物医药有限公司 | 强毒性淀粉样蛋白寡聚体的诊断用途 |
CN117491650A (zh) * | 2023-11-01 | 2024-02-02 | 首都医科大学宣武医院 | 一种外周血Hb-Aβ复合物定量检测试剂盒、检测方法及应用 |
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-
2008
- 2008-05-29 PE PE2008000921A patent/PE20090329A1/es not_active Application Discontinuation
- 2008-05-29 US US12/129,469 patent/US20090175847A1/en not_active Abandoned
- 2008-05-30 MX MX2009012950A patent/MX2009012950A/es not_active Application Discontinuation
- 2008-05-30 WO PCT/US2008/065205 patent/WO2008150949A1/en active Application Filing
- 2008-05-30 PA PA20088782201A patent/PA8782201A1/es unknown
- 2008-05-30 AU AU2008260062A patent/AU2008260062A1/en not_active Abandoned
- 2008-05-30 CL CL2008001580A patent/CL2008001580A1/es unknown
- 2008-05-30 RU RU2009149370/10A patent/RU2009149370A/ru unknown
- 2008-05-30 UY UY31114A patent/UY31114A1/es not_active Application Discontinuation
- 2008-05-30 JP JP2010510504A patent/JP2010530740A/ja not_active Withdrawn
- 2008-05-30 BR BRPI0812005A patent/BRPI0812005A2/pt not_active IP Right Cessation
- 2008-05-30 CN CN200880101484A patent/CN101827862A/zh active Pending
- 2008-05-30 CA CA002687414A patent/CA2687414A1/en not_active Abandoned
- 2008-05-30 TW TW097120376A patent/TW200914465A/zh unknown
- 2008-05-30 EP EP08769847A patent/EP2150563A1/en not_active Withdrawn
- 2008-05-30 AR ARP080102298A patent/AR066794A1/es unknown
- 2008-05-30 KR KR1020097027470A patent/KR20100032398A/ko not_active Application Discontinuation
-
2009
- 2009-11-19 IL IL202243A patent/IL202243A0/en unknown
- 2009-11-27 DO DO2009000269A patent/DOP2009000269A/es unknown
- 2009-12-18 CR CR11179A patent/CR11179A/es not_active Application Discontinuation
- 2009-12-21 CO CO09145798A patent/CO6251291A2/es not_active Application Discontinuation
- 2009-12-29 EC EC2009009833A patent/ECSP099833A/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2008260062A1 (en) | 2008-12-11 |
CO6251291A2 (es) | 2011-02-21 |
DOP2009000269A (es) | 2009-12-15 |
EP2150563A1 (en) | 2010-02-10 |
PA8782201A1 (es) | 2009-02-09 |
KR20100032398A (ko) | 2010-03-25 |
PE20090329A1 (es) | 2009-03-27 |
MX2009012950A (es) | 2010-03-26 |
RU2009149370A (ru) | 2011-07-10 |
JP2010530740A (ja) | 2010-09-16 |
CN101827862A (zh) | 2010-09-08 |
BRPI0812005A2 (pt) | 2019-09-24 |
ECSP099833A (es) | 2010-01-29 |
CR11179A (es) | 2010-05-27 |
CL2008001580A1 (es) | 2008-12-05 |
AR066794A1 (es) | 2009-09-09 |
WO2008150949A1 (en) | 2008-12-11 |
IL202243A0 (en) | 2010-06-16 |
TW200914465A (en) | 2009-04-01 |
US20090175847A1 (en) | 2009-07-09 |
CA2687414A1 (en) | 2008-12-11 |
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