UY30407A1 - Derivados de [2,3,4,8-tetrahidroimidazo-[1,5-a]-pirimidin-8-il]-fenil sulfonatos sustituidos, composiciones farmacéuticas y aplicaciones. - Google Patents

Derivados de [2,3,4,8-tetrahidroimidazo-[1,5-a]-pirimidin-8-il]-fenil sulfonatos sustituidos, composiciones farmacéuticas y aplicaciones.

Info

Publication number
UY30407A1
UY30407A1 UY30407A UY30407A UY30407A1 UY 30407 A1 UY30407 A1 UY 30407A1 UY 30407 A UY30407 A UY 30407A UY 30407 A UY30407 A UY 30407A UY 30407 A1 UY30407 A1 UY 30407A1
Authority
UY
Uruguay
Prior art keywords
pirimidin
fenil
tetrahydroimidazo
derivatives
applications
Prior art date
Application number
UY30407A
Other languages
English (en)
Spanish (es)
Inventor
Maria Wirstam
Katharina Hogdin
Kihlstrom Jacob
Fernando Sehgelmeble
Niklas Plobeck
Stefan Berg
Original Assignee
Astex Therapeutics Ltd
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38831992&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY30407(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astex Therapeutics Ltd, Astrazeneca Ab filed Critical Astex Therapeutics Ltd
Publication of UY30407A1 publication Critical patent/UY30407A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
UY30407A 2006-06-14 2007-06-12 Derivados de [2,3,4,8-tetrahidroimidazo-[1,5-a]-pirimidin-8-il]-fenil sulfonatos sustituidos, composiciones farmacéuticas y aplicaciones. UY30407A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81372806P 2006-06-14 2006-06-14
US89699407P 2007-03-26 2007-03-26

Publications (1)

Publication Number Publication Date
UY30407A1 true UY30407A1 (es) 2008-01-31

Family

ID=38831992

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30407A UY30407A1 (es) 2006-06-14 2007-06-12 Derivados de [2,3,4,8-tetrahidroimidazo-[1,5-a]-pirimidin-8-il]-fenil sulfonatos sustituidos, composiciones farmacéuticas y aplicaciones.

Country Status (7)

Country Link
EP (1) EP2035423A1 (fr)
JP (1) JP2009539973A (fr)
AR (1) AR061369A1 (fr)
CL (1) CL2007001733A1 (fr)
TW (1) TW200815443A (fr)
UY (1) UY30407A1 (fr)
WO (1) WO2007145568A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7763609B2 (en) 2003-12-15 2010-07-27 Schering Corporation Heterocyclic aspartyl protease inhibitors
US7592348B2 (en) 2003-12-15 2009-09-22 Schering Corporation Heterocyclic aspartyl protease inhibitors
US7700603B2 (en) 2003-12-15 2010-04-20 Schering Corporation Heterocyclic aspartyl protease inhibitors
JP2008508289A (ja) 2004-07-28 2008-03-21 シェーリング コーポレイション 大環状βセクレターゼ阻害剤
AU2006259572A1 (en) 2005-06-14 2006-12-28 Schering Corporation Aspartyl protease inhibitors
KR20080028881A (ko) 2005-06-14 2008-04-02 쉐링 코포레이션 헤테로사이클릭 아스파르틸 프로테아제 억제제, 이의제조방법 및 용도
TW200815349A (en) 2006-06-22 2008-04-01 Astrazeneca Ab New compounds
WO2008063114A1 (fr) * 2006-11-20 2008-05-29 Astrazeneca Ab Amino-imidazolones et utilisation thérapeutique de ces composés pour traiter les troubles cognitifs, la maladie d'alzheimer, la neurodégénérescence et la démence
EP2288613B1 (fr) 2008-04-22 2016-07-13 Merck Sharp & Dohme Corp. Composes de 2-imino-3-methyl-pyrrolo pyrimidinone substitues par phenyle utilises en tant qu inhibiteurs bace-1, compositions et utilisation associees
TW201020244A (en) 2008-11-14 2010-06-01 Astrazeneca Ab New compounds
EP2485590B1 (fr) 2009-10-08 2015-01-07 Merck Sharp & Dohme Corp. Composés hétérocycliques de type imino-pentafluorosulfure utilisés en tant qu'inhibiteurs de bace1, compositions en contenant et leur utilisation
US8563543B2 (en) 2009-10-08 2013-10-22 Merck Sharp & Dohme Corp. Iminothiadiazine dioxide compounds as bace inhibitors, compositions, and their use
UA108363C2 (uk) 2009-10-08 2015-04-27 Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування
US8569310B2 (en) 2009-10-08 2013-10-29 Merck Sharp & Dohme Corp. Pentafluorosulfur imino heterocyclic compounds as BACE-1 inhibitors, compositions and their use
ES2558779T3 (es) * 2011-03-01 2016-02-08 Janssen Pharmaceutica, N.V. Derivados de 6,7-dihidro-pirazolo[1,5-a]piracin-4-ilamina útiles como inhibidores de ß-secretasa (BACE)
WO2012138734A1 (fr) 2011-04-07 2012-10-11 Merck Sharp & Dohme Corp. Composés de dioxyde de thiadiazine condensés avec des dérivés oxacycliques en c5-c6 comme inhibiteurs de bace, compositions, et utilisation use
US9145426B2 (en) 2011-04-07 2015-09-29 Merck Sharp & Dohme Corp. Pyrrolidine-fused thiadiazine dioxide compounds as BACE inhibitors, compositions, and their use
JP2014524472A (ja) 2011-08-22 2014-09-22 メルク・シャープ・アンド・ドーム・コーポレーション Ｂａｃｅ阻害剤としての２−スピロ置換イミノチアジンならびにそのモノオキシドおよびジオキシド、組成物、ならびにそれらの使用
EP3607946B1 (fr) 2012-03-19 2023-02-22 Buck Institute for Research on Aging Inhibiteurs de bace spécifiques app (asbis) et leurs utilisations
US9422277B2 (en) 2012-10-17 2016-08-23 Merck Sharp & Dohme Corp. Tricyclic substituted thiadiazine dioxide compounds as BACE inhibitors, compositions and their use
WO2014062553A1 (fr) 2012-10-17 2014-04-24 Merck Sharp & Dohme Corp. Composés de dioxyde de thiadiazine substituée tricyclique utilisés en tant qu'inhibiteurs de bace, compositions et leur utilisation
ES2975235T3 (es) 2013-02-12 2024-07-04 Buck Inst Res Aging Hidantoínas que modulan el procesamiento de APP mediado por BACE
JP7419865B2 (ja) * 2020-02-17 2024-01-23 東ソー株式会社 芳香族ハロゲン化合物、その用途、及び製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1758907B1 (fr) * 2004-06-16 2009-02-18 Wyeth Diphenylimidazopyrimidine et -imidazole amines utilisees comme inhibiteurs de b-secretase
JP2008526966A (ja) * 2005-01-14 2008-07-24 ワイス β−セクレターゼの阻害のためのアミノ−イミダゾロン

Also Published As

Publication number Publication date
WO2007145568A9 (fr) 2008-12-11
TW200815443A (en) 2008-04-01
EP2035423A1 (fr) 2009-03-18
AR061369A1 (es) 2008-08-20
CL2007001733A1 (es) 2008-01-25
JP2009539973A (ja) 2009-11-19
WO2007145568A1 (fr) 2007-12-21

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20170627