UY29291A1 - Anticuerpos anti il-12, epitopos, composiciones, metodos y usos - Google Patents

Anticuerpos anti il-12, epitopos, composiciones, metodos y usos

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Publication number
UY29291A1
UY29291A1 UY29291A UY29291A UY29291A1 UY 29291 A1 UY29291 A1 UY 29291A1 UY 29291 A UY29291 A UY 29291A UY 29291 A UY29291 A UY 29291A UY 29291 A1 UY29291 A1 UY 29291A1
Authority
UY
Uruguay
Prior art keywords
methods
compositions
epithopes
antibodies anti
antibody
Prior art date
Application number
UY29291A
Other languages
English (en)
Inventor
Jill Giles-Komar
George Heavner
David Knight
Jinquan Iuo
David Peritt
Bernard Scallon
David Shealy
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of UY29291A1 publication Critical patent/UY29291A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5434—IL-12
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Abstract

Un anticuerpo anti-IL-12 que se une a una porción de la proteína IL-12 que corresponde a por lo menos un residuo un residuo de aminoácido seleccionado del grupo que consiste en los residuos 15, 17-21, 23, 40-43, 45-47, 54-56 y 58-62 de la secuencia de aminoácidos de la subunidad p40 de IL-12, que incluye los ácidos nucleicos aislados que codifican por lo menos un anticuerpo anti-IL-12, vectores, células huésped, animales transgénicos o plantas, y métodos para preparar y usar las mismas que tienen aplicaciones para composiciones,métodos y dispositivos diagnósticos y/o terapéuticos.
UY29291A 2004-12-21 2005-12-21 Anticuerpos anti il-12, epitopos, composiciones, metodos y usos UY29291A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63781904P 2004-12-21 2004-12-21

Publications (1)

Publication Number Publication Date
UY29291A1 true UY29291A1 (es) 2006-03-31

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UY29291A UY29291A1 (es) 2004-12-21 2005-12-21 Anticuerpos anti il-12, epitopos, composiciones, metodos y usos

Country Status (22)

Country Link
US (8) US8080247B2 (es)
EP (1) EP1836294A4 (es)
JP (1) JP2008523842A (es)
KR (1) KR20070094927A (es)
CN (1) CN101120087A (es)
AR (1) AR051805A1 (es)
AU (1) AU2005319278A1 (es)
BR (1) BRPI0515858A (es)
CA (1) CA2591813A1 (es)
CR (1) CR9265A (es)
EA (1) EA016022B1 (es)
IL (1) IL183939A0 (es)
MY (1) MY157915A (es)
NI (1) NI200700155A (es)
NO (1) NO20073778L (es)
NZ (2) NZ583153A (es)
PE (1) PE20061115A1 (es)
SG (1) SG158150A1 (es)
TW (1) TWI406943B (es)
UY (1) UY29291A1 (es)
WO (1) WO2006069036A2 (es)
ZA (1) ZA200706036B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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