CR9265A - Anticuerpos anti-il-12, y epitopes, composiciones, metodos de obtencion y usos de los mismos - Google Patents

Anticuerpos anti-il-12, y epitopes, composiciones, metodos de obtencion y usos de los mismos

Info

Publication number
CR9265A
CR9265A CR9265A CR9265A CR9265A CR 9265 A CR9265 A CR 9265A CR 9265 A CR9265 A CR 9265A CR 9265 A CR9265 A CR 9265A CR 9265 A CR9265 A CR 9265A
Authority
CR
Costa Rica
Prior art keywords
epithopes
antibodies
methods
compositions
obtaining
Prior art date
Application number
CR9265A
Other languages
English (en)
Inventor
Giles-Komar Jill
Heavner George
Knight David
Luo Jinquan
Peritt David
Scallon Bernard
Shealy David
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of CR9265A publication Critical patent/CR9265A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5434—IL-12
    • C—CHEMISTRY; METALLURGY
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Abstract

Un anticuerpo anti-IL-12 que se une a una porcion de la proteina de IL-12 que corresponde a por lo menos un residuo de aminoacido seleccionado del grupo que consiste de los residuos 15,17-21,23,40-43,45-47,54-56 y 58-62 de la secuencia de aminoacidos de la subunidad p40 de la IL-12, incluyendo acidos nucleicos aislados que codifican para por lo menos un anticuerpo anti-IL, vectores, celulas hospederas, animales o plantas trangenicos, metodos y dispositivos de diagnostico y/o terapeuticos.
CR9265A 2004-12-21 2007-07-20 Anticuerpos anti-il-12, y epitopes, composiciones, metodos de obtencion y usos de los mismos CR9265A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63781904P 2004-12-21 2004-12-21

Publications (1)

Publication Number Publication Date
CR9265A true CR9265A (es) 2009-01-16

Family

ID=36602254

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9265A CR9265A (es) 2004-12-21 2007-07-20 Anticuerpos anti-il-12, y epitopes, composiciones, metodos de obtencion y usos de los mismos

Country Status (22)

Country Link
US (8) US8080247B2 (es)
EP (1) EP1836294A4 (es)
JP (1) JP2008523842A (es)
KR (1) KR20070094927A (es)
CN (1) CN101120087A (es)
AR (1) AR051805A1 (es)
AU (1) AU2005319278A1 (es)
BR (1) BRPI0515858A (es)
CA (1) CA2591813A1 (es)
CR (1) CR9265A (es)
EA (1) EA016022B1 (es)
IL (1) IL183939A0 (es)
MY (1) MY157915A (es)
NI (1) NI200700155A (es)
NO (1) NO20073778L (es)
NZ (2) NZ583153A (es)
PE (1) PE20061115A1 (es)
SG (1) SG158150A1 (es)
TW (1) TWI406943B (es)
UY (1) UY29291A1 (es)
WO (1) WO2006069036A2 (es)
ZA (1) ZA200706036B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706264B1 (en) * 1994-03-14 2004-03-16 Genetics Institute, Llc Use of IL-12 antagonists in the treatment of conditions promoted by an increase in levels of IFN-y
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