US3874367A - Valved blood sampling needle assembly - Google Patents

Valved blood sampling needle assembly Download PDF

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Publication number
US3874367A
US3874367A US267559A US26755972A US3874367A US 3874367 A US3874367 A US 3874367A US 267559 A US267559 A US 267559A US 26755972 A US26755972 A US 26755972A US 3874367 A US3874367 A US 3874367A
Authority
US
United States
Prior art keywords
cannula
assembly
housing
rear end
opening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US267559A
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English (en)
Inventor
Waldemar A Ayres
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Priority to US267559A priority Critical patent/US3874367A/en
Priority to JP48047632A priority patent/JPS5229551B2/ja
Priority to GB2092173A priority patent/GB1378603A/en
Priority to FR7317753A priority patent/FR2190475B1/fr
Priority to CA171,733A priority patent/CA987987A/en
Priority to BR4008/73A priority patent/BR7304008D0/pt
Priority to DK354973A priority patent/DK150842C/da
Priority to DE2332967A priority patent/DE2332967C2/de
Priority to DE19732349997 priority patent/DE2349997A1/de
Priority to DE19732349996 priority patent/DE2349996A1/de
Application granted granted Critical
Publication of US3874367A publication Critical patent/US3874367A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221—Valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150351—Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A61B5/150404—Specific design of proximal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150473—Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • A61B5/150488—Details of construction of shaft
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150503—Single-ended needles
    • A61B5/150519—Details of construction of hub, i.e. element used to attach the single-ended needle to a piercing device or sampling device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150732—Needle holders, for instance for holding the needle by the hub, used for example with double-ended needle and pre-evacuated tube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154—Devices using pre-evacuated means
    • A61B5/1545—Devices using pre-evacuated means comprising means for indicating vein or arterial entry

Definitions

  • the [51] Int Cl A61m 5/00 A61b 5/14 assembly includes a housing, a forward penetrating [58] Fie'ld "5 F 2 G i R DIG 5 end for insertion into the patient, a rearward end for 128/272 3; 274 1 6 coupling with an evacuated collection container, a continuous passageway therethrough, and a resilient elastomeric valve member on the assembly normally in position to close the passageway between the pa- [56] References cued tient and the rearward end and adapted to be respon- UNITED STATES PATENTS sive to a predetermined decrease in pressure in the 3,203,545 8/1965 Grossman 206/632 R rearward end to deform and automatically open the 3,235,069 Bennett et al R passageway when an evacuated container is upled 312541671 6/1966 Will 128/105 X with the rearward end.
  • valve is responfi et sive to a predetermined increase in pressure in the 3566875 3/1971 gi i fi V rearward end of the assembly to automatically return 336011151 8/1971 V to the closed position and prevent flow of fluid from 3,659,587 5/1972 Baldwin 128/2 F the rear end Of the assembly to the P 3,734,08O 5/1973 Petterson et al.
  • the evacuated containers contain chemical materials, useful in the clinical laboratory tests to be conducted after mixing with the patients blood. How ever, these chemical materials may be harmful to a patient if any were to flow from the evacuated container into the patients blood system.
  • some evacuated containers are partially filled with protein culture medium, and the possibility exists that if any of this protein material were carried back into the patient, such foreign protein might cause anaphylactic shock. Therefore, it would be extremely desirable to utilize a system for blood sampling which employs evacuated containers in a manner such as in the systems described above and which would alleviate the danger of back flow of fluid into the patient during and after the fluid sampling process.
  • a needle assembly for use with an evacuated container in collecting blood samples wherein a one-way valve means is provided on the needle assembly to prevent the possibility of back flow of chemical materials from the evacuated container into the patient.
  • the valve is designed of a resilient elastomeric self-sealing material to automatically deform and open and permit flow into the evacuated container when the system is utilized under a low pressure differential and to automatically return to the normal closed position preventing flow to and from the forward end of the needle assembly when subjected to flow pressure from the rear end of the assembly to which the evacuated container is connected or exhaustion of the vacuum in an evacuated container utilized in a sampling collection operation.
  • a needle assembly for facilitating the collection of a blood sample from a patient into an evacuated collection container while alleviating the danger of flow of fluid from the collection container into the patient during and after collection of the blood sample.
  • the assembly includes a housing with a forward penetrating end including a cannula extending from the housing for penetration into the blood vessel of the patient.
  • the assembly also includes a rearward end extending from the housing and including a cannula and being adapted to be coupled in fluid communication with the interior of an evacuated collection container. Portions of the assembly form a passageway for directing blood from the vein to the collection container when the forward end is in the blood vessel and the rearward end is in the container.
  • an elastomeric resilient valve member is part of the assembly normally in position to close the passageway between the blood vessel and the rearward end of the assembly and adapted to be responsive to decrease in pressure in the rearward end to deform and automatically open the passageway when the evacuated container is coupled with the rearward end of the assembly. Thereafter. the valve is responsive to a predetermined increase in pressure in the rearward end to automatically return to the closed position and prevent flow of fluid from the rear end of the assembly to the patient.
  • FIG. 1 is a partially sectional side elevation view of the needle assembly of the invention shown incapsuled in a sealed container;
  • FIG. 2 is a side elevation view of the needle assembly of the invention shown in operable position in combination with a holder, an evacuated container, and a needle shield;
  • FIG. 3 is a fragmentary sectional elevation view thereof with the needle shield removed and the assembly in fluid communication with a blood vessel immediately prior to collection of a sample;
  • FIG. 4 is an enlarged fragmentary view of the valve portion of the needle assembly as shown in FIG. 3;
  • FIG. .5 is a fragmentary sectional view of the needle assembly in operable position with the valve portion open and blood being collected in an evacuated container;
  • FIG. 6 is an enlarged fragmentary view of the valve portion of the needle assembly of FIG. 5 with arrows showing the blood flowing through the needle assembly;
  • FIG. 7 is an enlarged sectional view of the needle assembly of the invention in operable position in the vein of the patient subsequent to collection of a sample in an evacuated container after the valve portion has reclosed;
  • FIG. 8 is an enlarged fragmentary view of the valve portion of the needle assembly of FIG. 7 with the valve having reclosed upon completion of collection of a sample.
  • needle assembly includes a housing 21 on the forward end of which is mounted a forward venipuncture cannula 22 and on the rear end of which is mounted a second cannula 23.
  • Housing 21 includes a forward end portion 24 having a passageway 25 therethrough. Mounted in passageway 25 is the rear end portion of venipuncture cannula 22. The cannula is held in position in a convenient manner such as by epoxy 26 as shown.
  • Forward portion 24 of housing 21 has a tapered frusto conical rear mating end 27 with a hollow interior.
  • the rear end portion of cannula 22 extends rearwardly from passageway 25 into the hollow interior of tapered frusto conical portion 27.
  • the forward end of cannula 22 extends from the forward tip of housing 21 and has a beveled tip 28 for insertion into the vein of a patient.
  • the rear end of cannula 22 has a blunt tip 29 and the end portion adjacent blunt tip which extends from passageway 25 has an elastomeric cap or valve member 30 mounted thereon.
  • Valve member 30 has a closed rear end and has its open forward end in sealing engagement with cannula 22. Between the rear end of valve 30 and blunt tip 29 of cannula 22, valve 30 has a hollow center 31 in communication with the passageway through cannula 22. Valve 30 is of a self-sealing elastomeric material and contains one or more slits 32 where hollow portion 31 is located. Valve 30 is of a lesser inner diameter than the outer diameter of cannula 22 so that when the sleeve or valve 30 is positioned on cannula 22 it is expanded at the location of contact so as to provide sealing interengagement between the cannula and valve sleeve.
  • Housing 21 is of a two-part construction with the tapered outer surface of forward portion 24 which forms frusto conical portion 27 in frictional engagement with a tapered inner surface of a rear end 33 of the housing.
  • Rear end 33 includes the hollow cylindrical portion 34 with a tapered inner surface in interengagement with forward end 24 and a rear cylindrical neck 35 having a passageway 36 therethrough.
  • the outer surface 37 of neck 35 is threaded for interengagement with a holder as will be discussed in detail below.
  • a chamber 38 is formed therein. Access to chamber 38 is gained through the hollow cannula 22 mounted in passageway 25 or through the hollow cannula 23 which is mounted in passageway 36.
  • Cannula 23 is mounted in a conventional manner such as by epoxy 39.
  • the forward tip of cannula 23 is located intermediate the ends of passageway 36 and the rear tip of cannula 23 extends beyond neck 35 and has a pointed end 40 for penetration into an evacuated container as will be discussed in detail below.
  • cap or valve 30 is housed within chamber 38 in housing 21.
  • needle assembly 20 is packaged for shipment and storage in a sealed aseptic fashion prior to use.
  • the package is in the form of a hollow capsule 41 of rigid material such as a rigid plastic in a two-part assembly.
  • the forward part 42 covers the forward part of needle assembly 20 and terminates intermediate the ends of housing 33.
  • the rear part 43 covers the rear end of the needle assembly and terminates below the lower end of housing 21.
  • Both the forward part 42 and the rear part 43 of capsule 41 have a closed end distal from one another and an open end proximal to one another for frictional interengagement to form capsule 41 with the needle assembly contained therein.
  • capsule 41 At the point of joinder of portions 42 and 43 of capsule 41 an outer cylindrical mating surface is formed on which is mounted a tamper-proof band 144. As long as band 144 is not disturbed and remains intact, the capsule 41 is unbroken and the assembly 20 contained therein remains in aseptic condition. The rigid nature of capsule 41 alleviates the danger of damage to the assembly during shipment, storage and handling prior to use. Assembly 20 is of a disposable nature so that, if desired, once capsule 41 is opened and assembly 20 is utilized it may be discarded.
  • tamper-proof band 144 is broken and capsule 41 is opened by removing rear portion 43 from forward portion 42 and from its surrounding relationship with the rear end of assembly 20.
  • Forward portion 42 of capsule 41 is retained in position covering venipuncture cannula 22 to alleviate the danger of contamination thereeof during the preliminary preparation procedures prior to use.
  • Removal of rear end 43 of capsule 41 exposes cannula 23 and neck 35 so that a holder 44 may be extended over cannula 23 and into threaded interengagement with threaded surface 37 of housing 33. In this position as shown in FIG. 2 cannula 23 is located within holder 44.
  • An evacuated container 45 is then partially inserted within holder 44 to the rear of tip 40 of cannula 23.
  • the evacuated container is of a conventional type having a tubular body 46 terminated in an open end which is capped and sealed by a punctureable self-sealing stopper 47.
  • the assembly is then in condition for the actual blood sampling operation and forward portion or shield portion 42 of capsule 41 can then be removed from frictional interengagement with housing 21 thereby exposing cannula 22.
  • tip 28 of cannula 22 is then inserted into vein 48 of a patient. Since valve 30 is closing the rear blunt end 29 of cannula 22, no blood can travel beyond hollow chamber 31 within valve 30 under the influence of venous pressure alone.
  • Evacuated container 45 is then extended forward until tip 40 of cannula 23 punctures through stopper 47 thereby providing communication between the interior of evacuated tube 45 and central chamber 38 of housing 21. Thereafter, the pressure differential interiorly and exteriorly of valve 30 caused by the vacuum within container 45 automatically opens slits 32 and permits blood to flow from the vein through cannula 22 through slits 32 through chamber 38 and then through cannula 23 into container 45. Flow will continue as long as the pressure differential exists. Therefore, once the vacuum is exhausted within container 45 valve 30 will automatically return to its normal configuration with slits 32 returning to the sealed position thereby shutting off the blood flow adjacent to blunt end 29 of cannula 22.
  • valve 30 Similarly, should a back pressure build up during the filling operation, the pressure differential will be disturbed and the increased pressure exteriorly of valve 30 will cause slits 32 to be closed and eliminate any danger of fluid flow into valve 30 and consequently into cannula 22 and the patient. As discussed above, this is particularly useful in instances where harmful materials to be used in later chemical analysis may be contained within tube 45 and it is extremely desirable to avoid any of the possibly harmful material entering the patient.
  • FIGS. 3-8 show the sequence of operations in the taking of a blood sample while alleviating the danger of blood flow or other fluid flow back through the needle into the patient.
  • FIGS. 3 and 4 show the venipuncture having been made in the vein 48 of a patient.
  • valve 30 With valve 30 in the closed position, no blood flow due to venous pressure can occur beyond valve 30 in the assembly.
  • the evacuated tube 45 is shown in position for engagement with the rear tip of the needle assembly. Thereafter, in FIGS. 5 and 6 the evacuated tube 45 has been coupled with assembly so that tip 40 of cannula 23 is within the evacuated tube 46.
  • the vacuum causes a pressure differential and reduces the pressure in chamber 38 so that slits 32 open in valve permitting blood to pass through needle assembly 20 into evacuated tube 46 for collection.
  • this force will cause slits 32 to return to their relaxed position sealing valve 30 and preventing flow in either direction within the assembly.
  • valve 30 When the vacuum has been exhausted in tube 46, the pressure will equalize on both sides of valve 30 and valve 30 will return to its normal relaxed position with slits 32 sealing the passageway through assembly 20. No flow can then occur between tip 28 and tip 40 of the cannulas of assembly 20.
  • the evacuated container 45 can then be removed from the needle assembly as shown in FIGS. 7 and 8 and processed as desired. Subsequent evacuated containers can then be coupled with assembly 20 in a similar manner for the collection of further samples.
  • the elastomeric material of the valve member permits close control over the opening and closing of the valve.
  • the valve is responsive to deform when subjected to a low threshold of differential pressure. This enables the valve to be extremely accurate in controlling the flow into an evacuated container when a predetermined amount of fluid such as blood is to be collected. As discussed above, this is extremely advantageous in the blood sampling field.
  • a needle assembly for facilitating the collection of a blood sample from a patient into an evacuated collection container while preventing flow of fluid from the collection container into the patient during and after collection of the blood sample comprising:
  • first double ended substantially rigid cannula having a passage therethrough mounted in fixed position in the opening in the forward end of the housing with the forward end of the cannula being pointed for venipuncture and the rear end of the cannula in the chamber of the housing;
  • a second double ended substantially rigid cannula having a passage therethrough mounted in fixed position in the opening in the rear end of the housing with the passage opening in the forward end of the second cannula in fluid communication with the chamber in the housing through the opening in the rear end of the housing and the rear end of the second cannula being pointed for insertion into an evacuated collection container thereby providing a continuous passage from the forward end of the first cannula to the rear end of the second cannula;
  • a resilient cylindrically shaped cap of elastomeric self-sealing material having an open end and a closed end;
  • the opening in the open end extending a substantial distance throughout the length of the cap and being of normally lesser diameter in at least the portion adjacent the open end than the outer diameter of the rear end of the first cannula;
  • the cap being mounted on the rear end of the first cannula in the chamber with the portion of the cap on the cannula in expanded condition so as to fit thereon in tight sealing engagement therewith;
  • At least one slit in the cap aligned with the opening therein and spaced from the portion of the cap mounted on the first cannula with the slit being normally closed; so as to close the passageway through the assembly and being responsive to a reduction in fluid pressure at the rearward end of the second cannula to resiliently deform independent of any force other than the reduction in fluid pressure and independent of orientation of the assembly so as to automatically open the passageway through the assembly, and thereafter be responsive to a predetermined increase in fluid pressure at the rearward end of the second cannula to automatically return to the closed position independent of any other force than the increase in fluid pressure and independent of orientation of the assembly.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Manufacturing & Machinery (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
US267559A 1972-06-29 1972-06-29 Valved blood sampling needle assembly Expired - Lifetime US3874367A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
US267559A US3874367A (en) 1972-06-29 1972-06-29 Valved blood sampling needle assembly
JP48047632A JPS5229551B2 (de) 1972-06-29 1973-05-01
GB2092173A GB1378603A (en) 1972-06-29 1973-05-02 Needle assemblies for use with apparatus for collecting blood samples
FR7317753A FR2190475B1 (de) 1972-06-29 1973-05-16
CA171,733A CA987987A (en) 1972-06-29 1973-05-17 One-way valve system
BR4008/73A BR7304008D0 (pt) 1972-06-29 1973-05-30 Montagem de agulha, processo, e dispositivo para facilitar a coleta de amostra de sangue, e valvula sensivel a pressao
DK354973A DK150842C (da) 1972-06-29 1973-06-27 Apparat til blodproevetagning
DE2332967A DE2332967C2 (de) 1972-06-29 1973-06-28 Kanüleneinheit zur Entnahme von Blutproben von einem Patienten
DE19732349997 DE2349997A1 (de) 1972-06-29 1973-06-28 Auf druck ansprechendes ventil
DE19732349996 DE2349996A1 (de) 1972-06-29 1973-06-28 Auf druck ansprechendes ventil. ausscheidung aus: 2332967

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US267559A US3874367A (en) 1972-06-29 1972-06-29 Valved blood sampling needle assembly

Publications (1)

Publication Number Publication Date
US3874367A true US3874367A (en) 1975-04-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
US267559A Expired - Lifetime US3874367A (en) 1972-06-29 1972-06-29 Valved blood sampling needle assembly

Country Status (8)

Country Link
US (1) US3874367A (de)
JP (1) JPS5229551B2 (de)
BR (1) BR7304008D0 (de)
CA (1) CA987987A (de)
DE (3) DE2332967C2 (de)
DK (1) DK150842C (de)
FR (1) FR2190475B1 (de)
GB (1) GB1378603A (de)

Cited By (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4099520A (en) * 1977-04-07 1978-07-11 Decker Donald H Blood sampling apparatus
US4106497A (en) * 1977-02-04 1978-08-15 Becton, Dickinson And Company Multiple sample needle assembly with indicator means
US4134512A (en) * 1977-06-08 1979-01-16 Becton, Dickinson And Company One-way evacuated tube stopper
US4150089A (en) * 1977-09-06 1979-04-17 Linet Michael S Multi-chamber test tube
US4244378A (en) * 1978-05-30 1981-01-13 The West Company Pressure responsive one-way valve for medical systems
US4256120A (en) * 1980-01-07 1981-03-17 Sherwood Medical Industries Inc. Fluid sample collection device
US4296759A (en) * 1977-06-27 1981-10-27 Sherwood Medical Industries Inc. Blood collection device and method with anti-backflow means
US4306557A (en) * 1978-08-29 1981-12-22 North Daniel A Vacuum urological surgical irrigating solution collecting system
US4325388A (en) * 1973-02-05 1982-04-20 Louis Bucalo Apparatus for collecting and processing body fluids
US4341212A (en) * 1980-07-18 1982-07-27 Albert Medwid Serous fluid drain kit
US4376439A (en) * 1979-04-28 1983-03-15 Lauterjung F G Suction bottle for medical purposes particularly for the connection of drainage tubes
US4398544A (en) * 1981-10-15 1983-08-16 Becton Dickinson And Company Single and multiple sample needle assembly with vein entry indicator
US4416291A (en) * 1981-07-20 1983-11-22 Becton Dickinson And Company Multiple sample needle assembly with vein entry indicator
EP0033528B1 (de) * 1980-02-04 1984-06-13 Becton Dickinson and Company Durchflussdosiergerät für Anwendung mit einem Blutentnahmeapparat
US4509534A (en) * 1982-06-14 1985-04-09 Tassin Jr Myron J Blood withdrawal apparatus and method of using same
WO1992004867A1 (en) * 1990-09-17 1992-04-02 Anders Trell A blood sampling device
US5154699A (en) * 1988-03-01 1992-10-13 Ryan Medical, Inc. Safety winged needle device for use with fistulas
US5626567A (en) * 1994-06-21 1997-05-06 Gmeiner; Wilhelm Syringe assembly
US5800395A (en) * 1996-12-05 1998-09-01 Mdc Investment Holdings, Inc. Medical device with retractable needle
US6004278A (en) * 1996-12-05 1999-12-21 Mdc Investment Holdings, Inc. Fluid collection device with retractable needle
WO2001013795A1 (en) 1999-08-23 2001-03-01 European Institute Of Science Disposable test vial with sample delivery device
US6533760B2 (en) 2000-05-02 2003-03-18 Becton, Dickinson And Company Flashback blood collection needle
US6659975B2 (en) * 2000-05-16 2003-12-09 Fuju Photo Film Co., Ltd. Plasma collecting device
US6712792B2 (en) 2001-05-02 2004-03-30 Becton, Dickinson And Company Flashback blood collection needle
US20050245870A1 (en) * 2004-05-03 2005-11-03 Leroy Brown Porous multiple sample sleeve and blood drawing device for flash detection
US20050245869A1 (en) * 2004-05-03 2005-11-03 Leroy Brown Blood drawing device with flash detction
US20050245885A1 (en) * 2004-05-03 2005-11-03 Leroy Brown Blood drawing device with flash detection
WO2005110224A1 (ja) 2004-05-17 2005-11-24 Sekisui Chemical Co., Ltd. 採血具の逆流防止構造、ルアー針、採血針及び採血ホルダー
US20070167914A1 (en) * 2002-06-11 2007-07-19 Bd Medical Products, Pte. Ltd Flashback blood collection needle with needle shield
US20080194986A1 (en) * 2004-06-02 2008-08-14 Becton, Dickinson And Company Blood collection set with venting mechanism
US20090088698A1 (en) * 2007-09-27 2009-04-02 Tyco Healthcare Group Lp Blood Collection Needle Assembly
US7615033B2 (en) 2004-08-16 2009-11-10 Becton, Dickinson And Company Flashback blood collection needle
WO2014019197A1 (zh) * 2012-08-02 2014-02-06 Zhang Jianming 具有伸缩保护套的针筒式真空采血器
AU2014200917B2 (en) * 2000-05-02 2016-02-18 Bd Medical Products Pte. Ltd Flashback blood collection needle
US20170020427A1 (en) * 2015-07-24 2017-01-26 Calliope Solutions, Inc. Blood sample optimization system and blood contaminant sequestration device and method
US20180116577A1 (en) * 2012-05-30 2018-05-03 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
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DE2332967A1 (de) 1974-01-10
DE2349997A1 (de) 1974-02-21
DK150842C (da) 1988-01-18
DE2349996A1 (de) 1974-02-21
DK150842B (da) 1987-07-06
FR2190475A1 (de) 1974-02-01
JPS5012892A (de) 1975-02-10
CA987987A (en) 1976-04-27
DE2332967C2 (de) 1984-01-12
BR7304008D0 (pt) 1974-08-29
FR2190475B1 (de) 1977-02-11
GB1378603A (en) 1974-12-27
JPS5229551B2 (de) 1977-08-02

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