US3828779A - Flex-o-jet - Google Patents

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US3828779A
US3828779A US31470572A US3828779A US 3828779 A US3828779 A US 3828779A US 31470572 A US31470572 A US 31470572A US 3828779 A US3828779 A US 3828779A
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cannula
orifice
vial
end
plug
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R Ogle
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IMS Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089Containers or vials which are to be joined to each other in order to mix their contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407Infusion of two or more substances
    • A61M5/1409Infusion of two or more substances in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/1475Inlet or outlet ports
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/201Piercing means having one piercing end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/2013Piercing means having two piercing ends
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096Combination of a vial and a syringe for transferring or mixing their contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2429Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by telescoping of ampoules or carpules with the syringe body

Abstract

A device for the introduction of liquid medication into a flexible bag for the administration of intravenous solutions. The device comprises an elongated generally cylindrical hollow tubular member having an open end and a closed end, a boss extending from the closed end, carried by the boss a cannula having a sharpened outer end, and a rigid sheath surrounding the cannula and carried by the boss. The sheath serves to limit the advancement of the cannula into an orifice having a diameter greater than that of said cannula. A thrust portion is provided within the tubular member and a fluid passage extends longitudinally through the center of the thrust portion. The lower end of the fluid passage communicates with the upper end of the cannula. A cylindrical vial having a resilient stopper in its open end seals on the inside walls of the vial. There are threads on the thrust portion and cooperating threads on the stopper adapted to be interlocked, whereby the plug can be interlocked with the thrust portion.

Description

United States Patent 191 Ogle Aug. 13, 1974 [5 7] ABSTRACT A device for the introduction of liquid medication into.

a flexible bag for the administration of intravenous so- I lutions. The device comprises an elongated generally cylindrical hollow tubular member having an open end and a closed end, a boss extending from the closed 7 end, carried by the boss a cannula having a sharpened outer end, and a rigid sheath surrounding the cannula and carried by the boss. The sheath serves to limit the advancement of the cannula into an orifice having a diameter greater than that of said cannula. A thrust [5 FLEX-O-JET I [75] Inventor: Robert Water Ogle, Newport Beach;

Calif.

[73] Assignee: IMS Limited, Wilmington, Del. [22] Filed: Dec. 13, 1972 [21] Appl. No.: 314,705

[52] US. Cl 128/272, 128/218 N [51] Int. Cl. A6lj 5/00, A61m 5/32 [58] Field of Search 128/221, 272, 215, 214.2, 128/214 C, 214 F, 214 D, 218 D, 218 N, 216

[56] References Cited UNITED STATES PATENTS 2,724,383 ll/l955 Lockhart l28/272 X 2,904,043 9/1959 Friedman l28/2l8 D 3,123,072 3/1964 Bellamy, .Ir. 128/221 3,390,677 7/1968 Razimbaud l28/2l4 C 3,416,528 l2/l968 Kahn l28/2l4.2 3,659,602 5/l972 Cloyd 128/220 FOREIGN PATENTS OR APPLICATIONS 236,947 l2/196l Australia 128/214 D 1,373,027 8/1964 France l28/2l4.2 1,082,035 6/1954 France l28/2l4 D 1,446,357 6/1966 France l28/214.2

portion is provided within the tubular member and a fluid passage extends longitudinally through the center of the thrust portion. The lower end of the fluid passage communicates with the upper end of the cannula. A cylindrical vial having a resilient stopper in its open end seals on the inside walls of the vial. There are threads on the thrust portion and cooperating threads on the stopper adapted to be interlocked, whereby the plug can be interlocked with the thrust portion.

2 Claims, 7 Drawing Figures PATENTEU AUG 1 31974 SHEEI 1 0F 3 PAIENIEDAum 3 m4 SHEET 2 (IF 3 PATENTED AUG I 31974 SHEET .3 OF 3 FlG.-5

FLEX-O-JET BACKGROUND OF THE iNvENTioN The present invention is concerned with a device which is useful for the addition of medicinal solutions to flexible intravenous solution bags. Various devices have been proposed for these purposes. In general, the devices involve the use of metal conventional syringes. The problems are several. First, medication for addition to intravenous solution bags is frequently of high concentration, much too high for direct injection into the patient. Thus, the packaging of concentrated medication in a syringe presents the hazard of mistaken use, viz, direct injection rather than dilution by addition to the intravenous solution. Secondly, the orifice or inlet on the typical intravenous solution bag is flexible as is the bagitself. The insertion of an ordinary syringe into the orifice tube can result in the puncturing of the orifice tube and/or bag 'unless great care is observed. The present invention effectively overcomes these problems in the art.

SUMMARY OF THE INVENTION Briefly, the present invention comprises a device for the introduction of liquid medication into-a flexible bag for the administration of intravenous solutions which comprises an elongated generally cylindrical hollow tubular member having an open end and a closed end, a boss extending from said closed end, carried by the boss a cannula having a sharpened outer end, a rigid sheath surrounding said cannula and carried by said boss, said sheath serving to limit the advancementof the cannula into an orifice having a diameter greater than that of said cannula; within said tubular member a thrust portion within said tubular member, a fluid passage extending longitudinally through the center of said thrust portion, the lower endof said fluid passage communicating with the upper end of said cannula, a cylindrical vial having a resilient stopper in its open end sealing on the inside walls of said vial, interlocking means on said thrust portion and cooperating interlocking means on said stopper, whereby upon interlocking of said plug with said thrust portion said vial is first held in an assembled but non-operating position and upon further interlocking of said plug with said cylindrical member, said plug is adapted to be pierced by said fluid passage and said fluid passage with said vial without the application of substantial axial pressure on said plug and said plug is locked securely to said cylindrical member to permit aspiration upon withdrawal of said vial or to permit expulsion of the contents of said vial upon exertion of pressure on said vial.

This invention also includes the combination of a flexible bag for intravenous solution having an additivereceiving orifice and an outletadapted to lead to an intravenous solution set, and a device for the introduction of liquid medication into said flexible bag comprising an elongated generally cylindrical hollow tubular member having an open end and a-elosed end, a boss extending from said closed end, carried by the boss a cannula having a sharpened outer end, a rigid sheath surrounding said cannula and carried by said boss, said orifice having a diameter greater than that of said cannula, said sharpened outer end being received in said orifice and said sheath engaging said orifice to limit the advancement of said cannula into the orifice; within said tubular member, a thrust portion within said tubular member, a fluid passage extending longitudinally through the center of said thrust portion, the lower end of said fluid passage communicating with the upper end of said cannula, a cylindrical vial having a resilient stopper in its open end sealing on the inside walls. of said vial, interlocking means on said thrust portion and cooperating interlocking means on said stopper, whereby upon interlocking of said plug with said thrust portion said vial is first held in an assembled but nonoperating position and upon further interlocking of said plug with said cylindrical member, said plug is adapted to be pierced by said fluid passage and said fluid passage communicated with said vial without the application of substantial axial pressure on said plug and said plug is lockedsecurely to said cylindrical member to permit aspiration upon withdrawal of said vial or to permit expulsion of the contents of said vial upon exertion of pressure on said-vial.

It is an object of the present invention to provide a novel device for the packaging of medication.

More particularly, it is an object of the present invention to provide for the packaging of medication in a disposable device.

Still another object of the present invention is to provide a disposable device for use in the addition of medication to intravenous solution bags.

These and other objects and advantages of the invention will be apparent from the more detailed description which follows taken in conjunction with the accompanying drawings.

Further, the device of the present invention includes a significant safety feature. Additivesfor intravenous solutions actually contain medication in a concentration unsuitable for direct injection into the human body. In fact, many of these additives are fatal if directly injected. The sheath on the device of this invention preventsthe accidental injection of the concentrated medication into the body. The sharpened cannula end of this invention also prevents coring of the rubber diaphragm on the intravenous solution bag. Coring results in bits of rubber falling into the solution which can result in the injection of this dangerous blood clotting material into the patient.

DESCRIPTION OF THE PREFERRED EMBODIMENTS Turning to the drawings:

FIG. 1 shows a perspective view of a conventional in travenous solution bag.

FIG. 2 is a partial side view of the bag in FIG. 1.

FIG. 3 is a sectional view of the upper portion of the bag of FIG. 1 taken along the line 3-3 in FIG. 2.

FIG. 4 shows, in assembled form, the bag of FIG. 1 in relationship to the novel syringe having a sheath.

FIG. 5 shows a sectional view of the novel syringe of the present invention in disassembled form.

FIG. 6 is an enlarged partial sectional view of the combination shown in FIG. 4.

FIG. 7 shows, in assembled form, the use of the intravenous administration bag after the addition of FIG. 4 has been completed.

Turning to the drawings in greater detail, the holder of FIGS. 4-6 comprises a generally cylindrical hollow thrust portion 10 having an open end 12 and a closed end 14. The cylindrical vial 16 has a resilient stopper 18 in its open end sealing on the inside walls of the vial 16. The stopper 18 generally, although not necessarily,

has a thin imperforate central diaphragm portion. The stopper 18 is provided with an externally threaded projection 20 thereon. The thrust portion has a needle 22 therein and a boss 24 on its exterior from which cannula 26 extends. The cannula 26 has a sharpened outer end 28. The sheath 30 is carried by boss 24 and surrounds cannula 26. The sheath 30 terminates short of the sharpened outer end 28 of cannula 26. The sheath 30 has an offset or shoulder 32 which functions as further hereinafter described. Thrust portion 10 may be surrounded by holder 34.

The upper end of needle 22 has a sharp terminal portion 38. The thurst portion 10 may have internal threads 40 in proximity to its upper end, the threads on the projection and the threads 40 being adapted when made up to cause said sharp terminal portion 38 of the needle 22 to puncture said stopper 18. When the projection 20 is made up with threads 40, the stopper 18 functions as a piston to expel the contents of the vial 16 through needle 22 as said vial 16 is advanced with respect to said thrust portion 10.

The flexible intravenous solution bag 42 usually has a heat-sealed peripheral portion 44 and a solutioncontaining zone 46. The bag also has a flexible orifice or inlet tube 48 and an outlet tube 50 which leads to a conventional intravenous solution administration set 52. The inlet tube and outlet tubes are provided with imperforate diaphragms 54 and 56, respectively, and removable caps or closures 58 and 60, respectively.

In operation, caps 58 and 60 are removed, the cannula 26 and sheath 30 are positioned as shown in FIG. 6, that is, the offset or shoulder 32 limits the advancement of cannula into tube 48 so that the sharpened end 28 of cannula 26 pierces diaphragm 54 but the inside of shoulder 32 engages the outer end 62 of tube 48, limiting the advancement of the cannula 26 within tube 48. The flat surface of the shoulder 32 also serves to maintain the cannula 26 in a parallel or longitudinal relationship with respect to the inside walls of tube 48, thereby reducing the possibility of the sharpened end 28 piercing the side of tube 48. By limiting the advancement of the cannula 26 in tube 48 there is no chance that the sharpened end 28 can pierce the solution-containing zone 46. Thus, the escape of solution and the introduction of contaminated hospital air into the system are prevented.

With the parts as shown in FIG. 4, the vial is normally first withdrawn slightly to aspirate from the bag into the vial approximately that volume of air corresponding to the volume ofadditive medication in the vial. Then, the contents of the vial are expressed into the bag. The purpose of such aspiration is to prevent rupture of the bag due to over-pressurization.

As will be understood by those skilled in the art, once solution, extending from the top of said bag, an additive-receiving flexible tube-like orifice and an outlet adapted to lead to an intravenous solution set, and a device for the introduction of liquid medication into said flexible bag comprising an elongated generally cylindrical hollow tubular member having an open end and a closed end,- a boss extending from said closed end, carried by the boss a cannula having a sharpened outer end, a rigid cylindrical sheath of fixed length surrounding said cannula and affixed to said boss, said sharpened outer end extending slightly beyond the free end of said sheath, said orifice having a diameter greater than that of said cannula, said sharpened outer end being received in said flexible tube-like orifice and said sheath engaging said orifice to limit the advancement of said cannula into the orifice; within said tubular member, a thrust portion, a fluid passage extending longitudinally through the center of said thrust portion, the lower end of said fluid passage communicating with the upper end of said cannula, a cylindrical vial having a resilient stopper in its open end sealing on the inside walls of said vial, interlocking means on said thrust portion and cooperating interlocking means on said stopper, whereby upon interlocking of said plug with said thrust portion said vial is first held in an assembled but non-operating position and upon further interlocking of said plug with said cylindrical member, said plug is adapted to be pierced by said fluid passage and said fluid passage communicated with said vial without the application of substantial axial pressure on said plug and said plug is locked securely to said cylindrical member to permit aspiration upon withdrawal of said vial or to permit expulsion of the contents of said vial upon exertion of pressure on said vial.

2. The combination of claim 1 wherein the sheath has two portions of different diameter, the outer portion having a diameter greater than the outside diameter of said orifice and the inner portion having a diameter less than the outside diameter of said orifice whereby an annular shoulder is provided at the junction of said portions which abuts the outer end of said orifice, said orifice having a lateral imperforate diaphragm which is pierced by said sharpened outer end when said shoulder and outer end of said orifice are in contact.

Claims (2)

1. The combination of a flexible bag for intravenous solution, extending from the top of said bag, an additive-receiving flexible tube-like orifice and an outlet adapted to lead to an intravenous solution set, and a device for the introduction of liquid medication into said flexible bag comprising an elongated generally cylindrical hollow tubular member having an open end and a closed end, a boss extending froM said closed end, carried by the boss a cannula having a sharpened outer end, a rigid cylindrical sheath of fixed length surrounding said cannula and affixed to said boss, said sharpened outer end extending slightly beyond the free end of said sheath, said orifice having a diameter greater than that of said cannula, said sharpened outer end being received in said flexible tube-like orifice and said sheath engaging said orifice to limit the advancement of said cannula into the orifice; within said tubular member, a thrust portion, a fluid passage extending longitudinally through the center of said thrust portion, the lower end of said fluid passage communicating with the upper end of said cannula, a cylindrical vial having a resilient stopper in its open end sealing on the inside walls of said vial, interlocking means on said thrust portion and cooperating interlocking means on said stopper, whereby upon interlocking of said plug with said thrust portion said vial is first held in an assembled but non-operating position and upon further interlocking of said plug with said cylindrical member, said plug is adapted to be pierced by said fluid passage and said fluid passage communicated with said vial without the application of substantial axial pressure on said plug and said plug is locked securely to said cylindrical member to permit aspiration upon withdrawal of said vial or to permit expulsion of the contents of said vial upon exertion of pressure on said vial.
2. The combination of claim 1 wherein the sheath has two portions of different diameter, the outer portion having a diameter greater than the outside diameter of said orifice and the inner portion having a diameter less than the outside diameter of said orifice whereby an annular shoulder is provided at the junction of said portions which abuts the outer end of said orifice, said orifice having a lateral imperforate diaphragm which is pierced by said sharpened outer end when said shoulder and outer end of said orifice are in contact.
US05314705 1972-12-13 1972-12-13 Flex-o-jet Expired - Lifetime US3828779A (en)

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Application Number Priority Date Filing Date Title
US05314705 US3828779A (en) 1972-12-13 1972-12-13 Flex-o-jet

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US05314705 US3828779A (en) 1972-12-13 1972-12-13 Flex-o-jet
CA184,226A CA1024411A (en) 1972-12-13 1973-10-25 Syringe
JP12229173A JPS5418516B2 (en) 1972-12-13 1973-11-01
DE19732356905 DE2356905A1 (en) 1972-12-13 1973-11-14 A filling apparatus infusionsbehaelter
GB5365073A GB1453085A (en) 1972-12-13 1973-11-19 Device for the transfer of liquid medication
ES1973198343U ES198343Y (en) 1972-12-13 1973-12-04 Device for introducing a liquid medication.
IT5418173A IT1000254B (en) 1972-12-13 1973-12-07 A device for the introduction of liquid medicament in a flexible container
FR7344219A FR2210418B3 (en) 1972-12-13 1973-12-11
US05/461,066 US3945382A (en) 1972-12-13 1974-04-15 Device for introduction of liquid medication into a flexible bag
HK31077A HK31077A (en) 1972-12-13 1977-06-16 A device for the transfer of liquid medication
MY7700273A MY7700273A (en) 1972-12-13 1977-12-30 A device for the transfer of liquid medication

Related Child Applications (1)

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US05/461,066 Division US3945382A (en) 1972-12-13 1974-04-15 Device for introduction of liquid medication into a flexible bag

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US3828779A true US3828779A (en) 1974-08-13

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US05314705 Expired - Lifetime US3828779A (en) 1972-12-13 1972-12-13 Flex-o-jet
US05/461,066 Expired - Lifetime US3945382A (en) 1972-12-13 1974-04-15 Device for introduction of liquid medication into a flexible bag

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Application Number Title Priority Date Filing Date
US05/461,066 Expired - Lifetime US3945382A (en) 1972-12-13 1974-04-15 Device for introduction of liquid medication into a flexible bag

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US (2) US3828779A (en)
JP (1) JPS5418516B2 (en)
CA (1) CA1024411A (en)
DE (1) DE2356905A1 (en)
ES (1) ES198343Y (en)
FR (1) FR2210418B3 (en)
GB (1) GB1453085A (en)
HK (1) HK31077A (en)
IT (1) IT1000254B (en)
MY (1) MY7700273A (en)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3976073A (en) * 1974-05-01 1976-08-24 Baxter Laboratories, Inc. Vial and syringe connector assembly
US4199062A (en) * 1978-04-13 1980-04-22 Baxter Travenol Laboratories, Inc. Liquid container with hang flap
US4203443A (en) * 1977-12-08 1980-05-20 Abbott Laboratories Additive transfer unit with interlocking means
US4232669A (en) * 1979-02-15 1980-11-11 Bristol Myers Co. Protective sheath for syringe needle
US4361253A (en) * 1980-08-04 1982-11-30 Instrumentation Laboratory Inc. Liquid transfer device
WO1982004398A1 (en) * 1981-06-12 1982-12-23 Niklasson Tage Arrangement for bags especially for infusion and procedure for their production
US4410321A (en) * 1982-04-06 1983-10-18 Baxter Travenol Laboratories, Inc. Closed drug delivery system
US4411662A (en) * 1982-04-06 1983-10-25 Baxter Travenol Laboratories, Inc. Sterile coupling
WO1983003539A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Container for mixing a liquid and a solid
US4467588A (en) * 1982-04-06 1984-08-28 Baxter Travenol Laboratories, Inc. Separated packaging and sterile processing for liquid-powder mixing
US4560382A (en) * 1983-08-15 1985-12-24 Terumo Corporation Medical container
US5700244A (en) * 1992-04-17 1997-12-23 Science Incorporated Fluid dispenser with fill adapter
US5807335A (en) * 1995-12-22 1998-09-15 Science Incorporated Fluid delivery device with conformable ullage and fill assembly
US6086560A (en) * 1992-04-17 2000-07-11 Science Incorporated Fluid dispenser with fill adapter
US6090071A (en) * 1992-04-17 2000-07-18 Science Incorporated Fluid dispenser with fill adapter
US20110166968A1 (en) * 2010-01-06 2011-07-07 Richard Yin-Ching Houng System and method for activating display device feature
CN102836075A (en) * 2011-06-22 2012-12-26 重庆莱美药业股份有限公司 Anti-pollution medicine mixing port

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169475A (en) * 1977-12-08 1979-10-02 Abbott Laboratories Additive transfer unit
US4259952A (en) * 1978-06-22 1981-04-07 Avoy Donald R Blood diluting method and apparatus
US4235344A (en) * 1979-01-29 1980-11-25 Baxter Travenol Laboratories, Inc. Irrigation cap
CA1171030A (en) * 1979-11-05 1984-07-17 David Bellamy Fluid transfer assembly
US4614267A (en) * 1983-02-28 1986-09-30 Abbott Laboratories Dual compartmented container
US4722727A (en) * 1984-07-18 1988-02-02 Abbott Laboratories Flexible container
EP0692235A1 (en) * 1994-07-14 1996-01-17 International Medication Systems (U.K.) Ltd. Mixing & dispensing apparatus
US5782383A (en) * 1996-09-04 1998-07-21 Rexan Closures Inc. Dispensing closure for sealed enteral fluid containers
FR2829691B1 (en) * 2001-09-17 2004-07-09 Sedat A two-way transfer of a liquid between a vial and an ampoule
WO2003031042A1 (en) * 2001-10-09 2003-04-17 Immedica (A New Jersey Corporation) Multi-component, product handling and delivering system
DE102007046951B3 (en) * 2007-10-01 2009-02-26 B. Braun Melsungen Ag Means for introducing a medicament into an infusion container
DE102009013211B4 (en) 2009-03-17 2012-04-19 Aap Biomaterials Gmbh Vacuum mixing device for bone cement and method for mixing bone cement
CN102836071A (en) * 2011-06-22 2012-12-26 重庆莱美药业股份有限公司 Medicine mixing port
CN102836074B (en) * 2011-06-22 2016-05-25 重庆莱美药业股份有限公司 Interface mixed drug dustproof
DE102011112516A1 (en) 2011-09-07 2013-03-07 Aap Biomaterials Gmbh Liquid container with predetermined breaking point

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1082035A (en) * 1953-05-28 1954-12-24 Apparatus for collecting, preserving and distributing human blood
US2724383A (en) * 1951-06-28 1955-11-22 Compule Corp Combined mixing container structure and hypodermic syringe for segregated ingredients of hypodermically injectable preparations
US2904043A (en) * 1954-02-10 1959-09-15 Friedman Benjamin Hypodermic syringes
US3123072A (en) * 1959-03-09 1964-03-03 Flexible tube coupling- and closing apparatus
FR1373027A (en) * 1963-05-22 1964-09-25 An improved device for opening of a container or of a particular sealed conduit for infusion and transfusion
FR1446357A (en) * 1965-05-28 1966-07-22 Medicoplast Labor Improvements to infusion devices or transfusion and particularly to blood sampling devices
US3390677A (en) * 1964-07-10 1968-07-02 Razimbaud Jacquez Device for perfusion of sterile solutions and transfusion of blood
US3416528A (en) * 1959-08-17 1968-12-17 Cutter Lab Blood handling equipment
US3659602A (en) * 1970-12-30 1972-05-02 Nosco Plastics Two component syringe

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA686219A (en) * 1964-05-12 Baxter Laboratories Parenteral solution equipment
FR751433A (en) * 1932-05-28 1933-09-04 Therapeutiquescientifique Appl Needles for hypodermic injections
DE1441924A1 (en) * 1960-03-07 1969-03-27 Sokol Dr Kurt Heilmittelbehaelter for two before their injection to be mixed remedies
US3336924A (en) * 1964-02-20 1967-08-22 Sarnoff Two compartment syringe package
US3378008A (en) * 1965-07-23 1968-04-16 Min I Jet Corp Hypodermic syringe with vial
US3542023A (en) * 1968-03-06 1970-11-24 Min I Mix Corp Minimix

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2724383A (en) * 1951-06-28 1955-11-22 Compule Corp Combined mixing container structure and hypodermic syringe for segregated ingredients of hypodermically injectable preparations
FR1082035A (en) * 1953-05-28 1954-12-24 Apparatus for collecting, preserving and distributing human blood
US2904043A (en) * 1954-02-10 1959-09-15 Friedman Benjamin Hypodermic syringes
US3123072A (en) * 1959-03-09 1964-03-03 Flexible tube coupling- and closing apparatus
US3416528A (en) * 1959-08-17 1968-12-17 Cutter Lab Blood handling equipment
FR1373027A (en) * 1963-05-22 1964-09-25 An improved device for opening of a container or of a particular sealed conduit for infusion and transfusion
US3390677A (en) * 1964-07-10 1968-07-02 Razimbaud Jacquez Device for perfusion of sterile solutions and transfusion of blood
FR1446357A (en) * 1965-05-28 1966-07-22 Medicoplast Labor Improvements to infusion devices or transfusion and particularly to blood sampling devices
US3659602A (en) * 1970-12-30 1972-05-02 Nosco Plastics Two component syringe

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3976073A (en) * 1974-05-01 1976-08-24 Baxter Laboratories, Inc. Vial and syringe connector assembly
US4203443A (en) * 1977-12-08 1980-05-20 Abbott Laboratories Additive transfer unit with interlocking means
US4199062A (en) * 1978-04-13 1980-04-22 Baxter Travenol Laboratories, Inc. Liquid container with hang flap
US4232669A (en) * 1979-02-15 1980-11-11 Bristol Myers Co. Protective sheath for syringe needle
US4361253A (en) * 1980-08-04 1982-11-30 Instrumentation Laboratory Inc. Liquid transfer device
WO1982004398A1 (en) * 1981-06-12 1982-12-23 Niklasson Tage Arrangement for bags especially for infusion and procedure for their production
US4484920A (en) * 1982-04-06 1984-11-27 Baxter Travenol Laboratories, Inc. Container for mixing a liquid and a solid
US4411662A (en) * 1982-04-06 1983-10-25 Baxter Travenol Laboratories, Inc. Sterile coupling
WO1983003539A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Container for mixing a liquid and a solid
WO1983003586A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Closed drug delivery system
WO1983003540A1 (en) * 1982-04-06 1983-10-27 Baxter Travenol Lab Sterile coupling
US4432755A (en) * 1982-04-06 1984-02-21 Baxter Travenol Laboratories, Inc. Sterile coupling
US4410321A (en) * 1982-04-06 1983-10-18 Baxter Travenol Laboratories, Inc. Closed drug delivery system
US4467588A (en) * 1982-04-06 1984-08-28 Baxter Travenol Laboratories, Inc. Separated packaging and sterile processing for liquid-powder mixing
US4458733A (en) * 1982-04-06 1984-07-10 Baxter Travenol Laboratories, Inc. Mixing apparatus
US4560382A (en) * 1983-08-15 1985-12-24 Terumo Corporation Medical container
AU569733B2 (en) * 1983-08-15 1988-02-18 Terumo Kabushiki Kaisha Medical container for fluids
US5700244A (en) * 1992-04-17 1997-12-23 Science Incorporated Fluid dispenser with fill adapter
US6086560A (en) * 1992-04-17 2000-07-11 Science Incorporated Fluid dispenser with fill adapter
US6090071A (en) * 1992-04-17 2000-07-18 Science Incorporated Fluid dispenser with fill adapter
US5807335A (en) * 1995-12-22 1998-09-15 Science Incorporated Fluid delivery device with conformable ullage and fill assembly
US20110166968A1 (en) * 2010-01-06 2011-07-07 Richard Yin-Ching Houng System and method for activating display device feature
CN102836075A (en) * 2011-06-22 2012-12-26 重庆莱美药业股份有限公司 Anti-pollution medicine mixing port
CN102836075B (en) * 2011-06-22 2016-05-25 重庆莱美药业股份有限公司 Mixing one kind of antifouling agent interfaces

Also Published As

Publication number Publication date
GB1453085A (en) 1976-10-20
CA1024411A (en) 1978-01-17
CA1024411A1 (en)
IT1000254B (en) 1976-03-30
HK31077A (en) 1977-06-24
FR2210418B3 (en) 1976-10-15
US3945382A (en) 1976-03-23
JPS5418516B2 (en) 1979-07-07
FR2210418A1 (en) 1974-07-12
DE2356905A1 (en) 1974-06-27
MY7700273A (en) 1977-12-31
ES198343Y (en) 1975-11-01
JPS4989394A (en) 1974-08-27
ES198343U (en) 1975-06-01

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