US3390677A - Device for perfusion of sterile solutions and transfusion of blood - Google Patents

Device for perfusion of sterile solutions and transfusion of blood Download PDF

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Publication number
US3390677A
US3390677A US47044065A US3390677A US 3390677 A US3390677 A US 3390677A US 47044065 A US47044065 A US 47044065A US 3390677 A US3390677 A US 3390677A
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Prior art keywords
blood
receptacle
chamber
device
needle
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Expired - Lifetime
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Razimbaud Jacquez
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Razimbaud Jacquez
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165Filtering accessories, e.g. blood filters, filters for infusion liquids

Description

J. RAZIMBAUD 3,390,677 DEVICE FOR PERFUSION OF STERILE SOLUTIONS AND July 2, 1968 TRANSFUSION OF BLOOD Filed July 8 1965 United States Patent 81,56 3 Claims. (Cl. 128-414) ABSTRACT OF THE DISCLOSURE A perfusion and transfusion device with a sterile solution or blood storage receptacle, a chamber connected to the outlet of said storage receptacle and having a pierceable transverse wall in the course of said outlet, and a dispensing receptacle in fluid-tight movable engagement with said chamber, formed with a hollow needle arranged to pierce said transverse wall in response to the movement of said chamber in relation to said dispensing receptacle. The relative movement of the dispensing receptacle and chamber is governed by at least one lug projecting from said chamber and engaging with a cam slot in said dispensing receptacle.

This invention relates to devices for the perfusion of sterile solutions and transfusion of blood.

The devices for this purpose commonly in use to-day comprise a storage receptacle for the blood or the sterile solution which can be pierced by a needle in a sterile housing and connected by a tube to a blood dispensing receptacle to which an injection needle can be connected by a flexible tube.

The invention is concerned with an improved device of that general kind which consists in forming the dispensing receptacle and the needle as a unit which can be stored as such, free from contamination, until required for use.

The device in accordance with the invention comprises a storage receptacle for the blood or sterile solution having a pierceable wall, a dispensing receptacle for blood or sterile solution drawn from the storage receptacle and a needle for piercing the wall of the storage receptacle and providing a passage for the flow of blood or sterile solution therethrough to the dispensing receptacle. The needle is fixed to and forms a unit with the dispensing receptacle and its piercing end is housed in a chamber depending from the storage receptacle and has a fluid-tight connection with the dispensing receptacle which allows relative movement of the two receptacles to cause the needle to pierce the storage receptacle.

In the preferred form of the invention, the wall of the needle housing chamber is engaged in an annular bore in a wall of the dispensing receptacle. In that case, the wall of the needle housing chamber can have at least one lug projecting from it into engagement with a cam slot in a part of the dispensing receptacle which converts rotary movement of the storage receptacle into axial movement. Such a cam slot can usefully have portions in which the lugs can be engaged to hold the two receptacles against relative axial movement with the needle in either of its extreme positions relatively to the storage receptacle.

The dispensing receptacle can also usefully have a removable cap, provided if desired with a blood or solution filter to which an injection needle can be connected.

An example of a sterile solution perfusing and blood transfusing device in accordance with the invention is shown in the accompanying drawings in which:

FIGURE 1 shows the device in outside elevation and FIGURE 2 is a section taken on the line II-II in FIG- URE 1; and

FIGURE 3 is a section taken on the line III-III in FIGURE 2.

The illustrated device has two main parts 1 and 8.

The part 1 which is mounted on the part 8 for movement relatively thereto comprises a lower skirted portion 2 surmounted by a part 3 of smaller diameter closed at two thirds of its height by a thin wall 4 which separates it from a blood storage receptacle 5 welded or otherwise fixed to it. These parts although shown of circular crosssection could be of polygonal cross-section.

The skirt 2 engages in an annular bore 6 in an upper extension 7 of the cylindrical or polygonal part 8 which constitutes a blood or solution dispensing receptacle.

The skirt 2 is provided at its lower end with two cylindrical diametrically opposite lugs 10 which are engaged in two cam slots 11 in the outer wall of the annular bore 6, each of these slots having a horizontal part 12 followed by a vertical part 13, an inclined part 14 and another horizontal part 15 (see FIGURE 1).

The upper end 7 of the dispensing receptacle 8 has a central bore 16 in which is fixed by adhesion, soldering or welding a hollow needle 17 the lower end of which lies within the space 9 of that receptacle and the upper end of which lies within the movable part 1. The dispensing receptacle element 8 has a reinforcing ring 18 formed with diametrically opposite notches 19 leading to the annular bore 6 so as to allow the two parts 1 and 8 to be assembled for storage.

The skirt of the part 2 has at its lower end one or more beads 20 (only one shown) providing a space which can be filled with an impermeable viscous substance 21 impregnated with bacteriostatic germicides forming a seal and a joint which is permanently smooth between the inner wall of the skirted part 2 and the inner bounding surface 6a of the annular bore 6. Even if a substantial pressure is exerted here, this viscous substance prevents any risk of contamination while ensuring perfect fluidtightness. The dispensing receptacle 8 is provided at its lower end with a removable plug 22 which can be fixed by adhesion, soldering or welding and is provided with a tubular extension 23 allowing the receptacle 9 to be connected to an injection needle by means of a flexible tube 24. If desired, the plug can be provided with a blood or solution filter 25.

The device described above is used in the following manner:

The device is available in the ready for use condition shown in FIGURE 1, that is to say, with the part 1 in the elevated position, its lower end being engaged in the annular bore 6 and the lugs 8 being engaged in the upper horizontal parts 12 of the cam slots 11. The device will have been previously sterilized either by steam under pressure or by the action of gaseous germicidal agents, and the device placed in a sterile atmosphere in a welded plastic container.

When the device is to be used, the part 1 is rotated in the direction of the arrow F (FIGURE 3) to bring the lugs 10 above the vertical parts 13 of the card slots 11 in order to enable it to be moved downwards as indicated by the arrow F1 (FIGURE 2). During this downward movement the end of the needle 17 perforates the thin wall 4 and penetrates into the blood or sterile solution storage receptacle 5 allowing the blood or sterile solution to flow out through the needle 17 into the dispensing receptacle 9. A second rotary movement is then imparted to the part 1 in the direction of the arrow F (FIGURE 3) so that the lugs 10 are brought into the lower horizontal parts 15 of the cam slots 11 to ensure locking of the part 1 in the position shown in chain lines in FIGURE 2 in which the whole of the blood or sterile solution contained in the storage receptacle 5 can flow into the dispensing receptacle 8 and thence through the flexible tube 24 to the injection needle. During these rotary and downward movements of the part 1, the viscous substance 21 ensures great smoothness of movement by acting as a lubricant. Also a fluid-tight seal between the inner -bounding wall of the part body 2 and the surface 6a of the annular bore 6 is permanently ensured because of the entrainment of a film of this sterile viscous substance over the surface 6a.

The parts of this device can be of any material which is transparent, sterilizable, neutral, rigid and non-deformable such as glass, polystyrene or Plexiglas.

What is claimed is:

1. A device for the perfusion of sterile solutions or transfusion of blood comprising a storage receptacle for the blood or sterile solution; a chamber attached to an outlet of said storage receptacle and having a pierceable wall in the course of said outlet; a dispensing receptacle being in fluid-tight connection at its input end to said chamber, said connection permitting relative movement of said chamber and said dispensing receptacle; and a needle fixedly attached to said dispensing receptacle and having its piercing end housed in said chamber whereby upon the relative movement of said chamber and said dispensing receptacle said needle pierces the wall of said chamber thereby permitting the flow of blood or sterile solution from said storage receptacle, through said chamher, said needle, and said dispensing receptacle, and out of the outlet of said dispensing receptacle, said dispensing receptacle being formed with at least one cam slot, and said chamber being formed with at least one lug projecting therefrom and engaging with the corresponding ca-m slot, whereby the direction of the relative movement of said chamber and said dispensing receptacle is controlled, said cam slot having portions in which the corresponding lug, when engaged therein, prevents relative axial movement of said chamber and said dispensing receptacle at either of the two extreme positions of said needle.

2. A device as recited in claim 1, in which a portion of said cam slot is adapted to convert rotary movement of said chamber into axial movement thereof.

3. A device for the perfusion of sterile solutions and the transfusion of blood comprising a storage receptacle for the blood or sterile solution having a pierceable wall; a chamber depending from said storage receptacle at said pierccable wall having at least one lug projecting there from; a dispensing receptacle formed with at least one cam slot adapted to receive the corresponding lug therein, said dispensing receptacle being in fluid-tight connection With said chamber, said connection permitting relative movement of said chamber and said storage receptacle as guided by said lug engaging said cam slot; and a hollow needle fixedly attached to said dispensing receptacle and having its piercing end housed in said chamber, where-by the relative movement of said chamber and said dispensing receptacle causes said needle to pierce the wall of said storage receptacle, thereby permitting the blood or sterile solution to flow from said storage receptacle through said chamber, said needle, and said dispensing receptacle, said cam slot having portions in which, when said corresponding lugs are engaged therein, relative axial movement between said chamber and said dispensing receptacle is prevented at the two extreme positions of said needle.

References Cited UNITED STATES PATENTS 3,021,841 2/1962 Burke 128214 3,127,892 4/1964 Bellamy 128-2142 3,206,073 9/1965 Scislowicz 222 FOREIGN PATENTS 1,228,983 3/1960 France. 1,282,046 12/1961 France.

DALTON L. TRULUCK, Primary Examiner.

US47044065 1964-07-10 1965-07-08 Device for perfusion of sterile solutions and transfusion of blood Expired - Lifetime US3390677A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR981560A FR1418064A (en) 1964-07-10 1964-07-10 improved apparatus for infusion and transfusion

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US3390677A true US3390677A (en) 1968-07-02

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BE (1) BE666170A (en)
CH (1) CH430953A (en)
DE (1) DE1491804A1 (en)
ES (1) ES315160A1 (en)
FR (1) FR1418064A (en)
GB (1) GB1077157A (en)
LU (1) LU49000A1 (en)
NL (1) NL6508873A (en)
OA (1) OA1767A (en)

Cited By (49)

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Publication number Priority date Publication date Assignee Title
US3557786A (en) * 1968-06-18 1971-01-26 Abbott Lab Administration apparatus for intravenous substances
US3828779A (en) * 1972-12-13 1974-08-13 Ims Ltd Flex-o-jet
US4265760A (en) * 1979-02-26 1981-05-05 Becton Dickinson & Company Device for dilution and delivery of in vivo chemicals
FR2560049A1 (en) * 1984-02-24 1985-08-30 Erba Farmitalia Safety device for connecting a syringe with the opening of a bottle containing a medicinal product or a small tube for providing a medicament from the syringe
WO1986001712A1 (en) * 1984-09-14 1986-03-27 Baxter Travenol Laboratories, Inc. Reconstitution device
US4685917A (en) * 1983-11-14 1987-08-11 Bieffe S.P.A. Sterilizable valvular systems for flexible containers
US5566845A (en) * 1995-02-01 1996-10-22 Idea Laboratories, Inc. Container having a seal puncturing device
DE19930791A1 (en) * 1999-07-03 2001-01-11 Fresenius Ag Lockable needle adapter
US20030199847A1 (en) * 2002-04-17 2003-10-23 Roger Akerlund Method and device for fluid transfer in an infusion system
US20050016620A1 (en) * 2002-04-26 2005-01-27 Stephen Proulx Disposable, sterile fluid transfer device
US20060189937A1 (en) * 2005-02-18 2006-08-24 Becton Dickinson And Company Bubble free - self primed IV set
US20060276759A1 (en) * 2003-01-21 2006-12-07 Peter Kinast Needle for penetrating a membrane
US20080022785A1 (en) * 2003-12-23 2008-01-31 Furey James F Disposable, pre-sterilized fluid receptacle sampling device
US20080097315A1 (en) * 2004-01-29 2008-04-24 Becton, Dickinson And Company Self priming intravenous delivery system
US20080223484A1 (en) * 2007-03-16 2008-09-18 Carmel Pharma Ab Piercing Member Protection Device
WO2008115102A1 (en) * 2007-03-16 2008-09-25 Carmel Pharma Ab A piercing member protection device
US20080277021A1 (en) * 2007-05-08 2008-11-13 Petri Horppu Fluid Transfer Device
US20080312633A1 (en) * 2007-06-13 2008-12-18 Anna Ellstrom Arrangement for use with a medical device
US20090057258A1 (en) * 2007-08-30 2009-03-05 Hakan Tornqvist Device, Sealing Member and Fluid Container
US20090069783A1 (en) * 2007-09-11 2009-03-12 Anna Ellstrom Piercing member protection device
US20090229671A1 (en) * 2007-11-16 2009-09-17 Millipore Corporation Fluid transfer device
US20100004602A1 (en) * 2008-07-01 2010-01-07 Carmel Pharma Ab Piercing Member Protection Device
EP2144589A1 (en) * 2007-05-08 2010-01-20 Carmel Pharma AB Fluid transfer device
US20100147402A1 (en) * 2008-12-15 2010-06-17 Carmel Pharma Ab Connector Device
US20100152669A1 (en) * 2008-12-15 2010-06-17 Carmel Pharma Ab Connection arrangement and method for connecting a medical device to the improved connection arrangement
US20100154569A1 (en) * 2008-12-18 2010-06-24 Millipore Corporation Device For The Transfer Of A Medium
US20100158759A1 (en) * 2008-12-18 2010-06-24 Millipore Corporation Device For The Transfer Of A Medium
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
CN101104083B (en) 2006-07-11 2011-06-22 上海康德莱企业发展集团有限公司 Double-cavity drop funnel blood transfusion device
US8029747B2 (en) 2007-06-13 2011-10-04 Carmel Pharma Ab Pressure equalizing device, receptacle and method
US8162013B2 (en) 2010-05-21 2012-04-24 Tobias Rosenquist Connectors for fluid containers
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US8382711B2 (en) 2010-12-29 2013-02-26 Baxter International Inc. Intravenous pumping air management systems and methods
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US8544497B2 (en) 2009-10-30 2013-10-01 Emd Millipore Corporation Fluid transfer device and system
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US3021841A (en) * 1957-03-14 1962-02-20 Baxter Laboratories Inc Intravenous administration equipment
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US3127892A (en) * 1960-07-13 1964-04-07 Baxter Laboratories Inc Blood handling apparatus
FR1282046A (en) * 1960-12-06 1962-01-19 A punching device for opening a bottle and more particularly to a usable bottle for infusion and consisting of a plastic material
US3206073A (en) * 1963-02-13 1965-09-14 Abbott Lab Dispensing assembly for a container and a sheath therefor

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3557786A (en) * 1968-06-18 1971-01-26 Abbott Lab Administration apparatus for intravenous substances
US3828779A (en) * 1972-12-13 1974-08-13 Ims Ltd Flex-o-jet
US4265760A (en) * 1979-02-26 1981-05-05 Becton Dickinson & Company Device for dilution and delivery of in vivo chemicals
US4685917A (en) * 1983-11-14 1987-08-11 Bieffe S.P.A. Sterilizable valvular systems for flexible containers
FR2560049A1 (en) * 1984-02-24 1985-08-30 Erba Farmitalia Safety device for connecting a syringe with the opening of a bottle containing a medicinal product or a small tube for providing a medicament from the syringe
US4576211A (en) * 1984-02-24 1986-03-18 Farmitalia Carlo Erba S.P.A. Safety device for connection of a syringe with the mouth or opening of a bottle containing a drug or a small tube for drug delivery from the syringe
WO1986001712A1 (en) * 1984-09-14 1986-03-27 Baxter Travenol Laboratories, Inc. Reconstitution device
US4759756A (en) * 1984-09-14 1988-07-26 Baxter Travenol Laboratories, Inc. Reconstitution device
US5566845A (en) * 1995-02-01 1996-10-22 Idea Laboratories, Inc. Container having a seal puncturing device
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Also Published As

Publication number Publication date
GB1077157A (en) 1967-07-26
LU49000A (en)
NL6508873A (en) 1966-01-11
LU49000A1 (en) 1965-09-06
ES315160A1 (en) 1966-02-01
OA1767A (en) 1970-01-14
BE666170A (en) 1965-12-30
CH430953A (en) 1967-02-28
DE1491804A1 (en) 1969-06-12
FR1418064A (en) 1965-11-19

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