US3693320A - Novel capsule finishing apparatus - Google Patents

Novel capsule finishing apparatus Download PDF

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Publication number
US3693320A
US3693320A US88053A US3693320DA US3693320A US 3693320 A US3693320 A US 3693320A US 88053 A US88053 A US 88053A US 3693320D A US3693320D A US 3693320DA US 3693320 A US3693320 A US 3693320A
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Prior art keywords
chamber
capsules
chute
air stream
vacuum
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Expired - Lifetime
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US88053A
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English (en)
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Carl C Garland
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Individual
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Individual
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
    • B07B7/00—Selective separation of solid materials carried by, or dispersed in, gas currents
    • B07B7/06—Selective separation of solid materials carried by, or dispersed in, gas currents by impingement against sieves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07B—SEPARATING SOLIDS FROM SOLIDS BY SIEVING, SCREENING, SIFTING OR BY USING GAS CURRENTS; SEPARATING BY OTHER DRY METHODS APPLICABLE TO BULK MATERIAL, e.g. LOOSE ARTICLES FIT TO BE HANDLED LIKE BULK MATERIAL
    • B07B4/00—Separating solids from solids by subjecting their mixture to gas currents
    • B07B4/08—Separating solids from solids by subjecting their mixture to gas currents while the mixtures are supported by sieves, screens, or like mechanical elements

Definitions

  • PATENTEDsms I972 SHEET 2 OF 3 INVENTOR. CARL C. GARLAND ATTORNEY PATENTEDscrzs I972 3,693,320
  • This invention relates to novel apparatus and means for finishing filled pharmaceutical capsules. More particularly, the invention relates to finishing apparatus for processing joined capsules in a vacuum to reject defective capsules and eliminate surface powders and the like.
  • the prior art has had the problem of keeping the filling room in good order and free of spillage.
  • Another problem has been that of cleaning filled capsules so that excess material used for filling is completely removed from the capsule exterior in order that the same will have a pleasing appearance and will be free of the taste and order of the product.
  • One method for cleaning capsules involves agitating the filled capsules in a bed of common salt. The cleaning action in this case is due to presence of moisture in the salt which serves to absorb or take up surface dust, leaving the capsule wall clean. While the prior art cleaning action is useful, the method is cumbersome to operate and it fails to disqualify or reject capsules which are not completely joined or are defective due to the presence of cracks or holes in the capsule wall.
  • the prior art method also suffers from the disadvantage that unless done promptly after filling, the excess filling material may become permanently impregnated into the capsule wall or may absorb moisture which in turn may adversely affect the capsule wall.
  • Another object is to provide controlled air cleaning means for finishing filled capsules.
  • Still another object is to provide means for ridding the filling area of excess dust, powder spillage, etc.
  • FIG. I is a side view of a cleaning assembly according to the invention.
  • FIG. 2 is a top view of the assembly taken on line 2 2 of FIG. 1 showing a vacuum chamber in combination with a filling chute for the chamber;
  • FIG. 3 is a detailed illustration of the filling chute
  • FIGS. 4 and 4a are views of the vacuum chamber inlet
  • FIG. 5 is a view, partly in section, of a shell remover according to the invention.
  • FIG. 6 is an end view of the shell remover.
  • the preferred apparatus illustrated in FIG. I includes a vacuum chamber 10, a filler housing 30, and a transfer chute 40.
  • the chamber 10 has a cylindrical head 11 which merges with a conical or funnel-shaped body 12 having an access opening or orifice 13 at its lower end.
  • the chamber 10 includes a flat circular top 14 with a central exhaust opening or port 15.
  • the top 14 is removably attached to the head 11 by any suitable means such as tie rods 16 and retaining wing nuts 17.
  • the underside of the top is provided with an integral conical screen or baffle 19 mounted under and spanning the exhaust opening 15.
  • the baffle walls 21 are slanted symmetrically away from the center axis (preferably at an angle of about 30 to from the vertical axis) and have an open mesh structure or evenly spaced perforations 22.
  • top 14 and baffle 19 are removable as a single unit so that the baffle walls 21 are directly exposed for cleaning.
  • a conduit and T-valve 26 mounted with a suitable vacuum source for exhausting air in the direction shown by arrow 29.
  • the source is a commercially available vacuum cleaner supplied under the name Toronado (rated at 5 H.P., Breuer Electric Mfg. Co., Chicago, Illinois, U.S.A.) and arranged to draw on a 1.5 inch flexible corrugated conduit; the exhaust port, body, and inlet 13 measure approximately 1.5, 6, and l /inches, respectively.
  • valve 26 When the valve 26 is in the open" position so that a vacuum is drawn on the chamber, air from the atmosphere is pulled into the chamber through inlet 13 and carried via body 12 upward through the head portion 11, and out of the chamber through the baffle perforations and exit port 15.
  • a preferred feature of the chamber is the symmetrical funnel shape of the body which advantageously serves to provide a gradually decreasing linear velocity of air flow in the direction from the opening 13 to the head portion, which in turn facilitates the uniform vertically cyclic fiow of capsules while being processed in the chamber.
  • the housing 30 is adapted to be mounted by suitable bracket means around the filling apparatus.
  • the apparatus may be any suitable capsule filling means having work positions where capsules are filled and joined and where there is a problem of dust removal, examples of such apparatus being Hofliger-Karg Type GKF700, Zanasi Model 2-25 and MG-2 Model G-36.
  • the apparatus illustrated comprises conventional filler components of a Model 8 filler, Parke, Davis & Company, Detroit, Michigan, USA. The latter has an ejector ring 32 and an ejector plate 36 arranged for pivoting to a position face-to-face in cooperation with parallel guide rods 37.
  • the space between the ring 32 and plate 36 is sufficient to accommodate placing the edges of the 50 joining rings (not shown) onto the guide rods, in juxtaposition with the ring and plate.
  • the ejector ring is power-driven to reciprocate axially back and forth by dwell foot-switch means under control of the operator,
  • the housing 30 has an open top 33 and funnel-like bottom 34 with a dropout opening 35 matching the mouth 42 of the transfer chute 40.
  • the housing 30 includes arms 38 at its lower end adapted for holding the transfer chute 40 in position.
  • the ejector plate 36 is mounted, in conventional fashion, for rotation back and forth from the standby position (as illustrated) to the operating position (shown in dotted outline).
  • the gate 26 and the chute 40 operate off shaft means power-driven by separate air pressure cylinders for synchronous rotation to vacuum and transfer positions, respectively, whenever the ejector plate is placed in the standby position.
  • the gate and the chute are returned to their standby or holding positions whenever the ejector plate is pivoted to the operating position. Since delays often occur in the filling operation, the apparatus may optionally include automatic timing and control means for returning the. gate and chute to their standby positions upon expiration of a predetermined time interval, e.g., after 1 minute has elapsed.
  • the transfer chute 40 is mounted by pivot shaft means 41 to rotate as indicated between the mentioned transfer position and the hold position shown in dotted outline.
  • the upper end of the chute 40 has the mentioned open mouth 42 bounded on its lower margin by a holding surface 42a; the lower end has a discharge opening 43.
  • the mouth 42 and the holding surface 42a have dimensions matching the drop-out opening 35.
  • the discharge opening 43 is formed to provide a close fit with the inlet edges 13a of the lower end of the chamber.
  • the chute has a transfer stop 45 and a holding stop 46 to constrain or limit the pivot movement between the transfer and holding positions.
  • shell remover means 50 (Figs. '5 and 6 illustrating a preferred embodiment) is provided.
  • the shell remover constitutes a tunnel overlying a conveyor 51 defining the path of travel of capsules.
  • the tunnel includes a hoodpiece which has side walls 53a and 53b, a top 54, an open entrance end 55, and an open exit end 56.
  • a chimney 58 mounted on the top of the hoodpiece and extend ing upward from the periphery of an exhaust opening 57 is a chimney 58 arranged in communication with a vacuum source.
  • the hoodpiece is removably mounted for vertically adjustable positioning upon the conveyor by means of the mounting slots 59, threaded studs 60, and wing nuts 61.
  • the bed or floor of the conveyor includes a uniform pattern of openings 62, slots or the like arranged to provide passageway means for upward air flow particularly throughout the tunnel floor.
  • the conveyor 51 is preferably a conventional air-driven vibratory chute or equivalent conveyor means.
  • the configuration and dimensions of the tunnel can be varied to meet changing requirements such as the size and filled weight of capsule being processed. In one embodiment, for example, using No.
  • the tunnel isabout 1% inch wide
  • the opening 57 is rectangular measuring 1% by 2 inches, and is located about 2% inches from the entrance opening 55 and 1% inch from the exit opening.
  • the height is adjustable within a range from about 34 to 1% inch.
  • the openings in the l conveyor floor within the tunnel are 0.156 inches in diameter spaced on 3/16 inch centers to provide about 60% void in the surface.
  • the operation of producing finished capsules with the means illustrated has what may be regarded as four steps: joining and ejecting, transferring the joined capsules to the vacuumchamber, cleaning the capsules while in the chamber, and collecting the cleaned capsules.
  • the joining rings (body ring with filled bodies and cap ring with empty caps) are manually transferred as a unit from the filling work station, placed on the guide rods 37 body ring first and adjusted face-to-face with the ejector ring so that the ejector fingers are in alignment with the joining ring channels.
  • the ejector plate 36 is manually pivoted to the operating position (dotted outline, FIG. 1) which pivoting action by the mentioned switch and pneumatic means causes the valve gate 26 and chute 40 to move to their holding positionswhereby vacuum in the chamber is broken.
  • the ejector ring fingers are advanced into the joining rings by the mentioned power means causing the capsules to be joined.
  • the operator then causes the ejector ring to retract, at the same time advancing the joined rings manually in phase with the ejector ring so that the joined capsules are ejected.
  • the capsules eject, they fall into the housing 30 and slide by gravity towards the drop-out opening 35 where they are restrained by the holding surface 42a of the chute standing as it does in the position illustrated in dotted outlinein FIG. 1.
  • the valve 26 is in the vacuum off position illustrated.
  • the operator then manually rotates the ejector plate 36 clockwise back to the standby position. This movement automatically causes the chute and the valve to return to the transfer and vacuum positions.
  • the discharge opening 43 has been seated against the edges 13a of the inlet opening 13 so that the same is sealed.
  • the seal purposely allows some air to enter which air serves to lift and move the capsules.
  • the air is continuously being exhausted from the chamber, and correspondingly the capsules are. in constant movement in the chamber, first rising and then falling back. As the capsules fall back they move against the oncoming flow of air.
  • the air chamber pressure is less than atmospheric since the inlet opening 13 restricts entry of air. In this way a sufficient vacuum is created in the chamber to cause the separation of any loose powder or particulate matter from the outer surfaces of each capsule.
  • Such powder and foreign matter are carried upward through the low pressure air stream through the perforations 22 of the baffle and out of the chamber through the exhaust port.
  • the slant walls 21 of the baffle provide a useful agitation effect.
  • the capsules in the chamber are continuously cycled against the baffle walls 21 in turbulent fashion during the period of the cleaning cycle.
  • the capsules strike the baffle, they abruptly undergo a change of direction whereby surface dust is in effect shaken loose and carried straight on through the baffle by way of the perforations.
  • the capsules rebound and in the usual case move laterally and strike the chamber walls, the impact of which also has the effect of jarring surface dust loose.
  • the mentioned impact actions serves not only to remove unwanted particulate matter but also to separate loosely joined or improperly joined capsules and it follows that these are emptied in due course, leaving the empty shells in the chamber.
  • the vacuum action also has a useful cleaning effect outside the chamber in that dust-laden air at the filling work station tends to gravitate and move downward through housing 30 and chute 40.
  • the environment is constantly being cleared of residual powder.
  • the operator can occasionally dust off the apparatus directly into the housing with the assurance that the unwanted dust will be purged automatically and carried away in the vacuum cycle.
  • the vacuum cycle continues until the operator activates the ejector plate to the down position (or until the mentioned automatic timer means bypasses the operation and terminates the vacuum cycle) at which time the valve gate 26 and chute 40 are phased into the unload position.
  • the vacuum is broken and air enters the chamber via the inlet opening and valve (in the direction of arrow 20). With the loss of the vacuum in the chamber the capsules, now clean, fall by gravity action downward through the access opening into a suitable collector, conveyor, or the like.
  • Capsules processed in the cleaner or other work station are according to the invention transferred directly or indirectly to the shell remover means 50 (arrow D, FIG. 5) along the path of the conveyor 51.
  • the conveyor is a rigid trough constructed of stainless steel or other suitable material, operating as part of a vibratory feed bowl.
  • the path of travel of filled capsules passes through the tunnel under vacuum to the exit end of the conveyor (arrow F, Fig. 5).
  • the construction of the tunnel is such that the air flow to the chimney 58 from the exit end 56 is greater than the air flow from the entrance end 55 thereby creating a back pressure or air curtain inside the tunnel at the exit end.
  • Apparatus for finishing pharmaceutical capsules comprising:
  • vacuum means for moving an air stream through the chamber in a vertical direction to cause capsules in the chamber to become airborne therein above the bottom of the chamber and to be lifted and tumbled in the air stream;
  • baffle means above the airborne capsules adapted to pass the air stream and to confine the capsules within the chamber;
  • the capsule introducing means comprising an open-ended chute, the chute being pivotable to a transfer position with one end of the chute in cooperative relation with the outlet means for transfer of articles therebetween.
  • outlet means is an opening located at the bottom of the chamber.
  • An apparatus in combination with control means for interrupting the air stream whereby capsules located in the chamber lack support and are discharged from the chamber via the opening in the bottom of the chamber.
  • baffle means includes perforate walls slanted away from the vertical at an angle sufficient to cause capsules moving upwardly to rebound toward side walls of the chamber.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Basic Packing Technique (AREA)
US88053A 1970-11-09 1970-11-09 Novel capsule finishing apparatus Expired - Lifetime US3693320A (en)

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US8805370A 1970-11-09 1970-11-09

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US (1) US3693320A (de)
JP (1) JPS5610061B1 (de)
DE (1) DE2152807C3 (de)
IT (1) IT942228B (de)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3863790A (en) * 1973-04-20 1975-02-04 Joseph S Kanarek Wrapper removal apparatus
US5122262A (en) * 1990-01-12 1992-06-16 Summers Thomas W Separator screen with intermittent vacuum
FR2730649A1 (fr) * 1995-02-16 1996-08-23 Macofar Spa Trieur de gelules mal remplies
US6434911B1 (en) * 1999-02-03 2002-08-20 Shionogi Qualicaps Co., Ltd. Defective capsule removing mechanism
US6739455B2 (en) 1999-02-03 2004-05-25 Shionogi Qualicaps Co., Ltd Defective capsule removing mechanism
US20120324828A1 (en) * 2010-03-01 2012-12-27 Yuyama Mfg. Co., Ltd. Powder removal device of medicine dispenser
US9962741B2 (en) * 2016-09-30 2018-05-08 Pelletron Corporation Compact dedusting apparatus with remote discharge

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02120360U (de) * 1989-03-14 1990-09-28

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1512323A (en) * 1923-10-08 1924-10-21 Halbert C Wallace Grain cleaner
US2789694A (en) * 1955-03-21 1957-04-23 Garlock Packing Co Mineral wool depelletizing apparatus
US3592689A (en) * 1970-01-28 1971-07-13 Nestle Lemur Co The Method and apparatus for cleaning dust from the exterior of capsules

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1512323A (en) * 1923-10-08 1924-10-21 Halbert C Wallace Grain cleaner
US2789694A (en) * 1955-03-21 1957-04-23 Garlock Packing Co Mineral wool depelletizing apparatus
US3592689A (en) * 1970-01-28 1971-07-13 Nestle Lemur Co The Method and apparatus for cleaning dust from the exterior of capsules

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3863790A (en) * 1973-04-20 1975-02-04 Joseph S Kanarek Wrapper removal apparatus
US5122262A (en) * 1990-01-12 1992-06-16 Summers Thomas W Separator screen with intermittent vacuum
FR2730649A1 (fr) * 1995-02-16 1996-08-23 Macofar Spa Trieur de gelules mal remplies
US6434911B1 (en) * 1999-02-03 2002-08-20 Shionogi Qualicaps Co., Ltd. Defective capsule removing mechanism
US6739455B2 (en) 1999-02-03 2004-05-25 Shionogi Qualicaps Co., Ltd Defective capsule removing mechanism
US20120324828A1 (en) * 2010-03-01 2012-12-27 Yuyama Mfg. Co., Ltd. Powder removal device of medicine dispenser
US9333541B2 (en) * 2010-03-01 2016-05-10 Yuyama Mfg. Co., Ltd. Powder removal device of medicine dispenser
US9962741B2 (en) * 2016-09-30 2018-05-08 Pelletron Corporation Compact dedusting apparatus with remote discharge

Also Published As

Publication number Publication date
DE2152807C3 (de) 1974-11-21
DE2152807B2 (de) 1974-04-25
DE2152807A1 (de) 1972-05-10
JPS5610061B1 (de) 1981-03-05
IT942228B (it) 1973-03-20

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