US3625353A - Package for sterilized articles - Google Patents

Package for sterilized articles Download PDF

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Publication number
US3625353A
US3625353A US828305A US3625353DA US3625353A US 3625353 A US3625353 A US 3625353A US 828305 A US828305 A US 828305A US 3625353D A US3625353D A US 3625353DA US 3625353 A US3625353 A US 3625353A
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US
United States
Prior art keywords
package
resin
adhesive agent
group
opening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US828305A
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English (en)
Inventor
Ichiro Ishii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jintan Terumo Co Ltd
Original Assignee
Jintan Terumo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jintan Terumo Co Ltd filed Critical Jintan Terumo Co Ltd
Application granted granted Critical
Publication of US3625353A publication Critical patent/US3625353A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26—Accessories or devices or components used for biocidal treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2577/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks, bags
    • B65D2577/10—Container closures formed after filling
    • B65D2577/20—Container closures formed after filling by applying separate lids or covers
    • B65D2577/2041—Pull tabs
    • B65D2577/205—Pull tabs integral with the closure

Definitions

  • Weiner ABSTRACT A package particularly adapted for use in sterilizing and storing medical implements, which comprises a plastics vessel having an opening for receiving or taking out the article. and a sealing sheet made of plastics-impregnated, gas-permeable moistureproof and germproof paper, and having a hot-melt-type adhesive agent coated on the back for sealing the opening.
  • FIG. 1 A first figure.
  • FIG.2 FIG. 3
  • the present invention relates to a package particularly adapted for use in the sterilizing and storing medical implements such as an injection needle or syringe.
  • the present invention has been accomplished in view of the aforementioned circumstances and is intended to provide a package for sterilized articles which permits easy gas sterilization after sealing with a sealing sheet, is capable of effectively preventing the intrusion of germs and moisture and further enables the sealing sheet to be easily removed in a perfect and medically satisfactory condition.
  • a package for sterilized articles which comprises a plastics vessel having an opening through which a sterilized article is received or taken out, and a sealing sheet made of plastics impregnated, moistureproof and germproof paper and coated on the back with a hot-melt-type adhesive agent for sealing the opening.
  • FIG. 1 is a longitudinal view of a sealed needle package according to an embodiment of the present invention
  • FIG. 2 is a bottom view of a sealing sheet showing a lattice pattern of an adhesive agent
  • FIG. 3 is a bottom view of a sealing sheet showing an alternate pattern of an adhesive agent
  • FIG. 4 is a side elevational view of a sealed package of a syrrnge.
  • Numeral 11 represents a hypodermic needle capsule open at the top and prepared from polyethylene integrally formed into such a shape as is capable of fixing a hypodermic needle a to the inner circumferential wall surface.
  • a sealing sheet 12 To the lip of the opening of the capsule II is lightly attached a sealing sheet 12 as shown in FIG. 1. Further, the sealing sheet 12 has a peeling tab 12a extending outward as illustrated in FIG. 2 or 3, which acts as a finger grip in removing the sealing sheet 12.
  • the sealing sheet 12 is prepared from Kraft paper, high quality paper or Japanese paper impregnated with synthetic resin in suitable concentration. However, most preferable is the type particularly consisting of long fibers and having good breatheability. It is further preferred that the sealing sheet be 100 i IL in thickness from the necessity of keeping the interior of the capsule free from the intrusion of germs as well as in view of sterilizing or sealing treatment of the capsule.
  • Preferable types of synthetic resin to be impregnated in the aforementioned paper are polyacrylic ester resin, polyvinyl alcohol resin. Before impregnated in the aforesaid paper, these synthetic resins are diluted with an organic solvent such as ethyl acetate.
  • the degree of concentration in which these synthetic resins are to be impregnated is determined in consideration of the required breatheability and moistureproofness of the resultant paper, i.e. lack of the synthetic resins impregnated in the paper will result in poor moistureproofness of the resultant paper, and overimpregnation of the synthetic resins will naturally result in poor gas permeability.
  • Kraft paper 98 microns in thickness impregnated with about 7 to 15 weight percent of polyacrylic ester resin based on the Kraft paper is suitably employed.
  • said degree of concentration be such that 100 ml. of air takes an average time of from 10 to 30 seconds in passing through an area of 645.16 mm. at a pressure of 87.9 g./cm. for obtaining sufficient moistureproofness of the paper and carrying out an efficient sterilization treatment of the package.
  • the underside of the sealing sheet 12 is coated with a hotmelt-type adhesive agent 13 in a latticed form as illustrated in FIG. 2 or by wavelike lines in FIG. 3.
  • the hot-melt adhesive agent generally comprises a base resin such as polyethylene or a copolymer of polyethylene and vinyl acetate, a viscosity-imparting agent such as rosin, its derivatives, or phenolic resin, and additionally waxes and antioxidants.
  • the hot-melt-type adhesive agent having the aforesaid composition which is free from a solvent is not in the danger of a solvent being evaporated as occurring in other solvent-bearing adhesive agents, and in consequence sterilized articles are not contaminated by such solvent and no reduction in volume of the adhesive agent coated occurs, thus preventing an uneven coating of the adhesive agent.
  • the hot-melt-type adhesive agent according to the present invention has further advantage that said radiation promotes the cross-linking of the synthetic resins used to increase the bonding strength.
  • the lattice-form application, as shown in FIG. 2, or wavelike pattern as shown in FIG. 3 of the aforesaid adhesive agent ensures good breatheability of the sealing sheet I2 and the complete seal of a bonded surface and also enables the sealing sheet to be cleanly removed.
  • the surface of the sealing sheet 12 which is coated with an adhesive agent 13 is brought face to face with the open portion of the capsule l I, after the needle a is inserted into said capsule to be securely supported therein, and thereafter said open portion is sealed by thermally melting the adhesive agent 13.
  • the heating temperature generally ranges from about to about 200 C., though it is somewhat dependent on the magnitude of pressure applied on the sealing sheet 12, as well as on the length of the heating time.
  • the interior of the package thus sealed is sterilized, as in the prior art package, with a sterilizing gas, for example, a gas mixture consisting of 20 percent by volume of ethylene oxide and 80 percent by volume of carbon dioxide or by means of radiation.
  • a sterilizing gas for example, a gas mixture consisting of 20 percent by volume of ethylene oxide and 80 percent by volume of carbon dioxide or by means of radiation.
  • FIG. 4 illustrates another embodiment of the invention, wherein a hypodermic syringe is housed in a vessel 21 vacuum moulded in conformity with the shape of the syringe b and having a lengthy opening.
  • the sealing sheet 23 impregnated of a suitable amount of polyvinyl alcohol resin, and coated of a hot-melttype adhesive agent in the same manner shown in FIG. 2 or 3.
  • gas-permeable area of the sealing sheet 23 is relatively large in comparison with the volume of the vessel 21, so that sterilizing gas treatment can be conducted effectively.
  • the package according to the present invention comprises a sealing sheet formed by impregnating its base material with synthetic resin-in suitable concentration, so that it not only enables gas sterilization and seals against the intrusion of germs and moisture to be unfailingly carried out but also allows the sealing sheet to be cleanly removed with ease. Further, when the received medical implement is unsealed there is no danger of the paper fiber of the sealing sheet being scattered perchange to be attached to the syringe. This is extremely favorable from the hygienic standpoint.
  • the package of the present invention displays many other advantageous practical effects, for example, that at the time of radiation sterilization which said package also permits, the radiation promotes a cross-linking reaction among the synthetic resins involved in the adhesive agent with the resultant increase in the bonding strength.
  • a package for a sterilized article which comprises:
  • a plastic vessel having an opening through which the article is introduced or removed and a marginal flange around the periphery of the opening;
  • hot-melt type adhesive agent comprises:
  • a base resin selected from the group consisting of polyethylene and a copolymer of polyethylene and vinyl acetate;
  • a viscosity-imparting agent selected from the group consisting of rosin, derivatives of rosin, and phenolic resin.
  • a package for a sterilized article which comprises:
  • a plastic vessel having an opening through which the article is received or taken out and a marginal flange around the periphery of the opening;
  • said hot-melt type adhesive agent including a. a base resin selected from the group consisting of polyethylene and a copolymer of polyethylene and vinyl acetate, and b. a viscosity-imparting agent selected from the group consisting of rosin, derivatives of rosin and phenolic resin.

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Packages (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
US828305A 1969-02-19 1969-05-27 Package for sterilized articles Expired - Lifetime US3625353A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP44011778A JPS4918196B1 (enrdf_load_stackoverflow) 1969-02-19 1969-02-19

Publications (1)

Publication Number Publication Date
US3625353A true US3625353A (en) 1971-12-07

Family

ID=11787397

Family Applications (1)

Application Number Title Priority Date Filing Date
US828305A Expired - Lifetime US3625353A (en) 1969-02-19 1969-05-27 Package for sterilized articles

Country Status (6)

Country Link
US (1) US3625353A (enrdf_load_stackoverflow)
JP (1) JPS4918196B1 (enrdf_load_stackoverflow)
DE (1) DE1927746A1 (enrdf_load_stackoverflow)
FR (1) FR2030530A5 (enrdf_load_stackoverflow)
GB (1) GB1229127A (enrdf_load_stackoverflow)
SE (1) SE370867B (enrdf_load_stackoverflow)

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854484A (en) * 1971-10-22 1974-12-17 R Jackson Endotracheal tube with liquid fillable cuff
US3923154A (en) * 1973-04-05 1975-12-02 Litton Business Systems Inc Sterilant package
US3939971A (en) * 1973-02-13 1976-02-24 Becton, Dickinson And Company Sterilant package assembly
US4828797A (en) * 1986-06-24 1989-05-09 Edward Weck Incorporated EO biological test pack
US5133454A (en) * 1990-12-06 1992-07-28 Hammer Steven G Intravenous catheter biohazard prevention packaging device
US5758775A (en) * 1996-07-22 1998-06-02 Lowe; Kim H. Protective kit for medical sharps and method for using same
US5997811A (en) * 1997-07-02 1999-12-07 Cohesion Technologies, Inc. Method for sterile syringe packaging and handling
US6026959A (en) * 1996-07-22 2000-02-22 Protec Medical Corporation Protective kit for medical sharps and method for using same
US6306254B1 (en) * 1997-04-04 2001-10-23 Fuji Photo Film Co., Ltd. Interleaf paper for photosensitive printing plate material
US20020069616A1 (en) * 1998-03-13 2002-06-13 Odell Robert B. Method and apparatus for manufacturing, filling and packaging medical devices and medical containers
US20030121812A1 (en) * 2001-12-28 2003-07-03 Sprieck Terry L. Medical needle assemblies
WO2004002848A1 (en) * 2002-06-26 2004-01-08 E. I. Du Pont De Nemours And Company Coated sheet materials and packages made therewith
US20060032768A1 (en) * 2001-08-10 2006-02-16 Seikagaku Corporation Prefilled injector package and sterilizing or disinfecting method therefor
US20080135443A1 (en) * 2006-11-22 2008-06-12 Becton, Dickinson And Company Extravascular system packaging systems
US20100159167A1 (en) * 2008-12-23 2010-06-24 Alkor Folien Gmbh Peelable sheet for fibrous substrates
US7766900B2 (en) 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
US20120152289A1 (en) * 2010-12-21 2012-06-21 Tara Denise Smith Sterilization Container With Disposable Liner
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US20150025473A1 (en) * 2012-02-13 2015-01-22 Becton, Dickinson And Company Medical cannula package
US20190001049A1 (en) * 2015-07-28 2019-01-03 Health Robotics S.R.L. Container for Closing Caps for Syringes
CN109239223A (zh) * 2018-10-12 2019-01-18 江苏力凡胶囊有限公司 一种用于空心胶囊乙酸残留量的测试方法

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5153585U (enrdf_load_stackoverflow) * 1974-10-22 1976-04-23
US5197361A (en) * 1991-10-11 1993-03-30 General Electric Company Surface contouring tool
DE4428291A1 (de) * 1994-08-10 1996-02-15 Borries Horst Von Verpackung für zu sterilisierende Artikel
US5807343A (en) * 1996-09-30 1998-09-15 Becton Dickinson And Company Protective sealing barrier for a syringe
JP3831505B2 (ja) * 1997-12-26 2006-10-11 生化学工業株式会社 医療用滅菌包装における滅菌方法
JP2000203675A (ja) * 1999-01-05 2000-07-25 Terumo Corp 医療器具用容器および医療器具
JP2006271461A (ja) * 2005-03-28 2006-10-12 Terumo Corp 医療用器具の製造方法
JP3845110B2 (ja) * 2006-01-06 2006-11-15 生化学工業株式会社 医療用滅菌包装における滅菌方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3061087A (en) * 1959-05-08 1962-10-30 Johnson & Johnson Sterile sponge package
US3123210A (en) * 1964-03-03 Package and seal
US3229813A (en) * 1959-05-08 1966-01-18 Johnson & Johnson Sterile package
US3247957A (en) * 1964-08-17 1966-04-26 Hospital Supply And Dev Compan Sterile packaging and the like
US3410395A (en) * 1967-07-14 1968-11-12 Gen Binding Corp Steam sterilizable package and method of making the same
US3435948A (en) * 1966-08-08 1969-04-01 Ethicon Inc Gas sterilizable package
US3485239A (en) * 1967-11-02 1969-12-23 Becton Dickinson Co Self-contained sterile syringe

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3036700A (en) * 1959-08-26 1962-05-29 Becton Dickinson Co Sterile hypodermic needle assembly and package
US3093242A (en) * 1961-07-10 1963-06-11 Aseptic Thermo Indicator Compa Packaged article for ethylene oxide sterilization and subsequent storage
DE1566618A1 (de) * 1966-07-12 1970-10-22 Jintan Terumo Co Sterile Injektionsnadelverpackung
US4113090A (en) * 1977-08-15 1978-09-12 Becton, Dickinson And Company Medical instrument package

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123210A (en) * 1964-03-03 Package and seal
US3061087A (en) * 1959-05-08 1962-10-30 Johnson & Johnson Sterile sponge package
US3229813A (en) * 1959-05-08 1966-01-18 Johnson & Johnson Sterile package
US3247957A (en) * 1964-08-17 1966-04-26 Hospital Supply And Dev Compan Sterile packaging and the like
US3435948A (en) * 1966-08-08 1969-04-01 Ethicon Inc Gas sterilizable package
US3410395A (en) * 1967-07-14 1968-11-12 Gen Binding Corp Steam sterilizable package and method of making the same
US3485239A (en) * 1967-11-02 1969-12-23 Becton Dickinson Co Self-contained sterile syringe

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854484A (en) * 1971-10-22 1974-12-17 R Jackson Endotracheal tube with liquid fillable cuff
US3939971A (en) * 1973-02-13 1976-02-24 Becton, Dickinson And Company Sterilant package assembly
US3923154A (en) * 1973-04-05 1975-12-02 Litton Business Systems Inc Sterilant package
US4828797A (en) * 1986-06-24 1989-05-09 Edward Weck Incorporated EO biological test pack
US5133454A (en) * 1990-12-06 1992-07-28 Hammer Steven G Intravenous catheter biohazard prevention packaging device
US5758775A (en) * 1996-07-22 1998-06-02 Lowe; Kim H. Protective kit for medical sharps and method for using same
US6026959A (en) * 1996-07-22 2000-02-22 Protec Medical Corporation Protective kit for medical sharps and method for using same
US6306254B1 (en) * 1997-04-04 2001-10-23 Fuji Photo Film Co., Ltd. Interleaf paper for photosensitive printing plate material
US5997811A (en) * 1997-07-02 1999-12-07 Cohesion Technologies, Inc. Method for sterile syringe packaging and handling
US20020069616A1 (en) * 1998-03-13 2002-06-13 Odell Robert B. Method and apparatus for manufacturing, filling and packaging medical devices and medical containers
USRE46510E1 (en) * 1998-03-13 2017-08-15 Becton, Dickinson And Company Method and apparatus for manufacturing, filling and packaging medical devices and medical containers
US6792743B2 (en) * 1998-03-13 2004-09-21 Becton, Dickinson And Company Method and apparatus for manufacturing, filling and packaging medical devices and medical containers
US20060032768A1 (en) * 2001-08-10 2006-02-16 Seikagaku Corporation Prefilled injector package and sterilizing or disinfecting method therefor
US20030121812A1 (en) * 2001-12-28 2003-07-03 Sprieck Terry L. Medical needle assemblies
US7491433B2 (en) 2002-06-26 2009-02-17 E.I. Du Pont De Nemours And Company Coated sheet materials and packages made therewith
US20060078700A1 (en) * 2002-06-26 2006-04-13 Bletsos Ioannis V Coated sheet materials and packages made therewith
WO2004002848A1 (en) * 2002-06-26 2004-01-08 E. I. Du Pont De Nemours And Company Coated sheet materials and packages made therewith
CN100429130C (zh) * 2002-06-26 2008-10-29 纳幕尔杜邦公司 涂覆片材材料和以此生产的包装材料
US20040028931A1 (en) * 2002-06-26 2004-02-12 Bletsos Ioannis V. Coated sheet materials and packages made therewith
US7766900B2 (en) 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US8444620B2 (en) 2005-02-21 2013-05-21 Biomet Biologics, Llc Method and apparatus for application of a fluid
US9028457B2 (en) 2005-02-21 2015-05-12 Biomet Biologics, Llc Method and apparatus for application of a fluid
US8042689B2 (en) 2006-11-22 2011-10-25 Becton, Dickinson And Company Extravascular system packaging systems
US20080135443A1 (en) * 2006-11-22 2008-06-12 Becton, Dickinson And Company Extravascular system packaging systems
US9211487B2 (en) 2008-04-04 2015-12-15 Biomet Biologics, Llc Sterile blood separating system
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
US20100159167A1 (en) * 2008-12-23 2010-06-24 Alkor Folien Gmbh Peelable sheet for fibrous substrates
US20120152289A1 (en) * 2010-12-21 2012-06-21 Tara Denise Smith Sterilization Container With Disposable Liner
US20150025473A1 (en) * 2012-02-13 2015-01-22 Becton, Dickinson And Company Medical cannula package
US9694129B2 (en) * 2012-02-13 2017-07-04 Becton, Dickinson And Company Medical cannula package
US20170266366A1 (en) * 2012-02-13 2017-09-21 Becton, Dickinson And Company Medical cannula package
US10583240B2 (en) * 2012-02-13 2020-03-10 Becton, Dickinson And Company Medical cannula package
US20190001049A1 (en) * 2015-07-28 2019-01-03 Health Robotics S.R.L. Container for Closing Caps for Syringes
US10632246B2 (en) * 2015-07-28 2020-04-28 Health Robotics S.R.L. Container for closing caps for syringes
CN109239223A (zh) * 2018-10-12 2019-01-18 江苏力凡胶囊有限公司 一种用于空心胶囊乙酸残留量的测试方法

Also Published As

Publication number Publication date
DE1927746A1 (de) 1970-09-03
JPS4918196B1 (enrdf_load_stackoverflow) 1974-05-08
SE370867B (enrdf_load_stackoverflow) 1974-11-04
GB1229127A (enrdf_load_stackoverflow) 1971-04-21
FR2030530A5 (enrdf_load_stackoverflow) 1970-11-13

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