US20190021322A9 - Use of an insecticidal carboxamide compound against pests on cultivated plants - Google Patents
Use of an insecticidal carboxamide compound against pests on cultivated plants Download PDFInfo
- Publication number
- US20190021322A9 US20190021322A9 US15/563,120 US201615563120A US2019021322A9 US 20190021322 A9 US20190021322 A9 US 20190021322A9 US 201615563120 A US201615563120 A US 201615563120A US 2019021322 A9 US2019021322 A9 US 2019021322A9
- Authority
- US
- United States
- Prior art keywords
- spp
- plant
- maize
- carboxamide compound
- mon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 carboxamide compound Chemical class 0.000 title claims abstract description 418
- 241000607479 Yersinia pestis Species 0.000 title claims abstract description 143
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 17
- 239000000203 mixture Substances 0.000 claims abstract description 316
- 230000000361 pesticidal effect Effects 0.000 claims abstract description 129
- 238000000034 method Methods 0.000 claims abstract description 122
- 241000238631 Hexapoda Species 0.000 claims abstract description 70
- 239000000463 material Substances 0.000 claims abstract description 45
- 238000010353 genetic engineering Methods 0.000 claims abstract description 35
- 230000012010 growth Effects 0.000 claims abstract description 33
- 230000004048 modification Effects 0.000 claims abstract description 14
- 238000012986 modification Methods 0.000 claims abstract description 14
- 230000036541 health Effects 0.000 claims abstract description 11
- 230000001965 increasing effect Effects 0.000 claims abstract description 9
- 240000008042 Zea mays Species 0.000 claims description 303
- 241000196324 Embryophyta Species 0.000 claims description 252
- 244000068988 Glycine max Species 0.000 claims description 168
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 168
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 claims description 155
- 235000009973 maize Nutrition 0.000 claims description 155
- 101000623895 Bos taurus Mucin-15 Proteins 0.000 claims description 145
- 235000007244 Zea mays Nutrition 0.000 claims description 137
- 150000001875 compounds Chemical class 0.000 claims description 129
- 235000010469 Glycine max Nutrition 0.000 claims description 91
- 101100497219 Bacillus thuringiensis subsp. kurstaki cry1Ac gene Proteins 0.000 claims description 89
- 229920000742 Cotton Polymers 0.000 claims description 73
- 101150065438 cry1Ab gene Proteins 0.000 claims description 62
- 244000299507 Gossypium hirsutum Species 0.000 claims description 57
- 235000009432 Gossypium hirsutum Nutrition 0.000 claims description 51
- XDDAORKBJWWYJS-UHFFFAOYSA-N glyphosate Chemical compound OC(=O)CNCP(O)(O)=O XDDAORKBJWWYJS-UHFFFAOYSA-N 0.000 claims description 43
- 241001367803 Chrysodeixis includens Species 0.000 claims description 40
- 240000007594 Oryza sativa Species 0.000 claims description 33
- 101150102059 cry3Aa gene Proteins 0.000 claims description 33
- 235000007164 Oryza sativa Nutrition 0.000 claims description 30
- 108090000623 proteins and genes Proteins 0.000 claims description 29
- 241000625764 Anticarsia gemmatalis Species 0.000 claims description 27
- 241000931750 Spodoptera cosmioides Species 0.000 claims description 27
- 241000256251 Spodoptera frugiperda Species 0.000 claims description 26
- 241001521235 Spodoptera eridania Species 0.000 claims description 24
- 241001147381 Helicoverpa armigera Species 0.000 claims description 23
- 239000004009 herbicide Substances 0.000 claims description 21
- 235000009566 rice Nutrition 0.000 claims description 21
- 238000009395 breeding Methods 0.000 claims description 20
- 230000001488 breeding effect Effects 0.000 claims description 20
- 239000000417 fungicide Substances 0.000 claims description 20
- 241000209140 Triticum Species 0.000 claims description 19
- 235000021307 Triticum Nutrition 0.000 claims description 19
- 239000004480 active ingredient Substances 0.000 claims description 19
- 230000002363 herbicidal effect Effects 0.000 claims description 17
- 235000013305 food Nutrition 0.000 claims description 15
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 15
- 239000002917 insecticide Substances 0.000 claims description 14
- 241000255777 Lepidoptera Species 0.000 claims description 13
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims description 12
- 239000005562 Glyphosate Substances 0.000 claims description 11
- 229940097068 glyphosate Drugs 0.000 claims description 11
- 244000098338 Triticum aestivum Species 0.000 claims description 9
- PPDBOQMNKNNODG-NTEUORMPSA-N (5E)-5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentanol Chemical compound C1=NC=NN1CC1(O)C(C)(C)CC\C1=C/C1=CC=C(Cl)C=C1 PPDBOQMNKNNODG-NTEUORMPSA-N 0.000 claims description 8
- IAJOBQBIJHVGMQ-UHFFFAOYSA-N 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid Chemical compound CP(O)(=O)CCC(N)C(O)=O IAJOBQBIJHVGMQ-UHFFFAOYSA-N 0.000 claims description 8
- 241000254173 Coleoptera Species 0.000 claims description 8
- 239000005561 Glufosinate Substances 0.000 claims description 8
- 241001414989 Thysanoptera Species 0.000 claims description 8
- 239000005859 Triticonazole Substances 0.000 claims description 8
- PSOVNZZNOMJUBI-UHFFFAOYSA-N chlorantraniliprole Chemical compound CNC(=O)C1=CC(Cl)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl PSOVNZZNOMJUBI-UHFFFAOYSA-N 0.000 claims description 8
- DVBUIBGJRQBEDP-UHFFFAOYSA-N cyantraniliprole Chemical compound CNC(=O)C1=CC(C#N)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl DVBUIBGJRQBEDP-UHFFFAOYSA-N 0.000 claims description 8
- 230000000855 fungicidal effect Effects 0.000 claims description 8
- KAATUXNTWXVJKI-NSHGMRRFSA-N (1R)-cis-(alphaS)-cypermethrin Chemical compound CC1(C)[C@@H](C=C(Cl)Cl)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 KAATUXNTWXVJKI-NSHGMRRFSA-N 0.000 claims description 7
- RAMUASXTSSXCMB-UHFFFAOYSA-N 3-bromo-N-{2-bromo-4-chloro-6-[(1-cyclopropylethyl)carbamoyl]phenyl}-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide Chemical compound C1CC1C(C)NC(=O)C1=CC(Cl)=CC(Br)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl RAMUASXTSSXCMB-UHFFFAOYSA-N 0.000 claims description 7
- 239000005660 Abamectin Substances 0.000 claims description 7
- 239000005886 Chlorantraniliprole Substances 0.000 claims description 7
- 239000005889 Cyantraniliprole Substances 0.000 claims description 7
- MIFOMMKAVSCNKQ-HWIUFGAZSA-N Metaflumizone Chemical compound C1=CC(OC(F)(F)F)=CC=C1NC(=O)N\N=C(C=1C=C(C=CC=1)C(F)(F)F)\CC1=CC=C(C#N)C=C1 MIFOMMKAVSCNKQ-HWIUFGAZSA-N 0.000 claims description 7
- 239000005869 Pyraclostrobin Substances 0.000 claims description 7
- 239000005842 Thiophanate-methyl Substances 0.000 claims description 7
- SXSGXWCSHSVPGB-UHFFFAOYSA-N fluxapyroxad Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=CC=C1C1=CC(F)=C(F)C(F)=C1 SXSGXWCSHSVPGB-UHFFFAOYSA-N 0.000 claims description 7
- LYCIJUPJINEHKS-UHFFFAOYSA-N n-[4-chloro-2-[(diethyl-$l^{4}-sulfanylidene)carbamoyl]-6-methylphenyl]-2-(3-chloropyridin-2-yl)-5-(trifluoromethyl)pyrazole-3-carboxamide Chemical compound CCS(CC)=NC(=O)C1=CC(Cl)=CC(C)=C1NC(=O)C1=CC(C(F)(F)F)=NN1C1=NC=CC=C1Cl LYCIJUPJINEHKS-UHFFFAOYSA-N 0.000 claims description 7
- IDDHTEDFEKWIOX-UHFFFAOYSA-N n-[4-chloro-2-[[di(propan-2-yl)-$l^{4}-sulfanylidene]carbamoyl]-6-methylphenyl]-2-(3-chloropyridin-2-yl)-5-(trifluoromethyl)pyrazole-3-carboxamide Chemical compound CC(C)S(C(C)C)=NC(=O)C1=CC(Cl)=CC(C)=C1NC(=O)C1=CC(C(F)(F)F)=NN1C1=NC=CC=C1Cl IDDHTEDFEKWIOX-UHFFFAOYSA-N 0.000 claims description 7
- HZRSNVGNWUDEFX-UHFFFAOYSA-N pyraclostrobin Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 HZRSNVGNWUDEFX-UHFFFAOYSA-N 0.000 claims description 7
- KNDVJPKNBVIKML-UHFFFAOYSA-N tetraniliprole Chemical compound CNC(=O)C1=CC(C#N)=CC(C)=C1NC(=O)C1=CC(CN2N=C(N=N2)C(F)(F)F)=NN1C1=NC=CC=C1Cl KNDVJPKNBVIKML-UHFFFAOYSA-N 0.000 claims description 7
- QGHREAKMXXNCOA-UHFFFAOYSA-N thiophanate-methyl Chemical compound COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC QGHREAKMXXNCOA-UHFFFAOYSA-N 0.000 claims description 7
- PGOOBECODWQEAB-UHFFFAOYSA-N (E)-clothianidin Chemical compound [O-][N+](=O)\N=C(/NC)NCC1=CN=C(Cl)S1 PGOOBECODWQEAB-UHFFFAOYSA-N 0.000 claims description 6
- ZFHGXWPMULPQSE-SZGBIDFHSA-N (Z)-(1S)-cis-tefluthrin Chemical compound FC1=C(F)C(C)=C(F)C(F)=C1COC(=O)[C@@H]1C(C)(C)[C@@H]1\C=C(/Cl)C(F)(F)F ZFHGXWPMULPQSE-SZGBIDFHSA-N 0.000 claims description 6
- HOKKPVIRMVDYPB-UVTDQMKNSA-N (Z)-thiacloprid Chemical compound C1=NC(Cl)=CC=C1CN1C(=N/C#N)/SCC1 HOKKPVIRMVDYPB-UVTDQMKNSA-N 0.000 claims description 6
- ZOCSXAVNDGMNBV-UHFFFAOYSA-N 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Chemical compound NC1=C(S(=O)C(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl ZOCSXAVNDGMNBV-UHFFFAOYSA-N 0.000 claims description 6
- 239000005877 Alpha-Cypermethrin Substances 0.000 claims description 6
- 239000005874 Bifenthrin Substances 0.000 claims description 6
- JFLRKDZMHNBDQS-UCQUSYKYSA-N CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C Chemical compound CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C JFLRKDZMHNBDQS-UCQUSYKYSA-N 0.000 claims description 6
- 239000005888 Clothianidin Substances 0.000 claims description 6
- 239000005899 Fipronil Substances 0.000 claims description 6
- 239000005900 Flonicamid Substances 0.000 claims description 6
- 239000005788 Fluxapyroxad Substances 0.000 claims description 6
- 239000005906 Imidacloprid Substances 0.000 claims description 6
- 239000005914 Metaflumizone Substances 0.000 claims description 6
- 239000005925 Pymetrozine Substances 0.000 claims description 6
- 239000005930 Spinosad Substances 0.000 claims description 6
- 239000005939 Tefluthrin Substances 0.000 claims description 6
- 239000005940 Thiacloprid Substances 0.000 claims description 6
- 239000005941 Thiamethoxam Substances 0.000 claims description 6
- OMFRMAHOUUJSGP-IRHGGOMRSA-N bifenthrin Chemical compound C1=CC=C(C=2C=CC=CC=2)C(C)=C1COC(=O)[C@@H]1[C@H](\C=C(/Cl)C(F)(F)F)C1(C)C OMFRMAHOUUJSGP-IRHGGOMRSA-N 0.000 claims description 6
- CWFOCCVIPCEQCK-UHFFFAOYSA-N chlorfenapyr Chemical compound BrC1=C(C(F)(F)F)N(COCC)C(C=2C=CC(Cl)=CC=2)=C1C#N CWFOCCVIPCEQCK-UHFFFAOYSA-N 0.000 claims description 6
- ZXQYGBMAQZUVMI-UNOMPAQXSA-N cyhalothrin Chemical compound CC1(C)C(\C=C(/Cl)C(F)(F)F)C1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 ZXQYGBMAQZUVMI-UNOMPAQXSA-N 0.000 claims description 6
- YKBZOVFACRVRJN-UHFFFAOYSA-N dinotefuran Chemical compound [O-][N+](=O)\N=C(/NC)NCC1CCOC1 YKBZOVFACRVRJN-UHFFFAOYSA-N 0.000 claims description 6
- 229940013764 fipronil Drugs 0.000 claims description 6
- RLQJEEJISHYWON-UHFFFAOYSA-N flonicamid Chemical compound FC(F)(F)C1=CC=NC=C1C(=O)NCC#N RLQJEEJISHYWON-UHFFFAOYSA-N 0.000 claims description 6
- 229940056881 imidacloprid Drugs 0.000 claims description 6
- YWTYJOPNNQFBPC-UHFFFAOYSA-N imidacloprid Chemical compound [O-][N+](=O)\N=C1/NCCN1CC1=CC=C(Cl)N=C1 YWTYJOPNNQFBPC-UHFFFAOYSA-N 0.000 claims description 6
- QHMTXANCGGJZRX-WUXMJOGZSA-N pymetrozine Chemical compound C1C(C)=NNC(=O)N1\N=C\C1=CC=CN=C1 QHMTXANCGGJZRX-WUXMJOGZSA-N 0.000 claims description 6
- 229940014213 spinosad Drugs 0.000 claims description 6
- NWWZPOKUUAIXIW-FLIBITNWSA-N thiamethoxam Chemical compound [O-][N+](=O)\N=C/1N(C)COCN\1CC1=CN=C(Cl)S1 NWWZPOKUUAIXIW-FLIBITNWSA-N 0.000 claims description 6
- IBSREHMXUMOFBB-JFUDTMANSA-N 5u8924t11h Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C(C)C)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 IBSREHMXUMOFBB-JFUDTMANSA-N 0.000 claims description 5
- 229950008167 abamectin Drugs 0.000 claims description 5
- LRZWFURXIMFONG-HRSIRGMGSA-N afidopyropen Chemical compound C([C@@]1(C)[C@H]2[C@]([C@H]3[C@@H](O)C=4C(=O)OC(=CC=4O[C@]3(C)[C@@H](O)C2)C=2C=NC=CC=2)(C)CC[C@@H]1OC(=O)C1CC1)OC(=O)C1CC1 LRZWFURXIMFONG-HRSIRGMGSA-N 0.000 claims description 5
- BNYCHCAYYYRJSH-UHFFFAOYSA-N 1h-pyrazole-5-carboxamide Chemical compound NC(=O)C1=CC=NN1 BNYCHCAYYYRJSH-UHFFFAOYSA-N 0.000 claims description 4
- CAAMSDWKXXPUJR-UHFFFAOYSA-N 3,5-dihydro-4H-imidazol-4-one Chemical compound O=C1CNC=N1 CAAMSDWKXXPUJR-UHFFFAOYSA-N 0.000 claims description 4
- 239000005894 Emamectin Substances 0.000 claims description 4
- 229930001406 Ryanodine Natural products 0.000 claims description 4
- JJSYXNQGLHBRRK-SFEDZAPPSA-N ryanodine Chemical compound O([C@@H]1[C@]([C@@]2([C@]3(O)[C@]45O[C@@]2(O)C[C@]([C@]4(CC[C@H](C)[C@H]5O)O)(C)[C@@]31O)C)(O)C(C)C)C(=O)C1=CC=CN1 JJSYXNQGLHBRRK-SFEDZAPPSA-N 0.000 claims description 4
- AWSZRJQNBMEZOI-UHFFFAOYSA-N 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate Chemical compound C=1C=C(C(C)(C)C)C=CC=1C(C#N)(C(=O)OCCOC)C(=O)C1=CC=CC=C1C(F)(F)F AWSZRJQNBMEZOI-UHFFFAOYSA-N 0.000 claims description 3
- 241000193388 Bacillus thuringiensis Species 0.000 claims description 3
- 239000005885 Buprofezin Substances 0.000 claims description 3
- 239000005655 Cyflumetofen Substances 0.000 claims description 3
- PRLVTUNWOQKEAI-VKAVYKQESA-N buprofezin Chemical compound O=C1N(C(C)C)\C(=N\C(C)(C)C)SCN1C1=CC=CC=C1 PRLVTUNWOQKEAI-VKAVYKQESA-N 0.000 claims description 3
- 230000001747 exhibiting effect Effects 0.000 claims description 2
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 claims 2
- 230000000853 biopesticidal effect Effects 0.000 claims 1
- CXEGAUYXQAKHKJ-NSBHKLITSA-N emamectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](NC)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 CXEGAUYXQAKHKJ-NSBHKLITSA-N 0.000 claims 1
- 238000002703 mutagenesis Methods 0.000 abstract description 30
- 231100000350 mutagenesis Toxicity 0.000 abstract description 30
- 206010061217 Infestation Diseases 0.000 abstract description 15
- 230000009931 harmful effect Effects 0.000 abstract description 5
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 141
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 135
- 244000061456 Solanum tuberosum Species 0.000 description 120
- 235000002595 Solanum tuberosum Nutrition 0.000 description 114
- 241001167018 Aroa Species 0.000 description 77
- 101100491986 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) aromA gene Proteins 0.000 description 77
- 101150037081 aroA gene Proteins 0.000 description 77
- 241000219146 Gossypium Species 0.000 description 71
- 235000006008 Brassica napus var napus Nutrition 0.000 description 49
- 150000003857 carboxamides Chemical class 0.000 description 49
- 240000002791 Brassica napus Species 0.000 description 44
- 235000009355 Dianthus caryophyllus Nutrition 0.000 description 40
- 240000006497 Dianthus caryophyllus Species 0.000 description 40
- 235000011293 Brassica napus Nutrition 0.000 description 35
- 240000000385 Brassica napus var. napus Species 0.000 description 35
- 239000003112 inhibitor Substances 0.000 description 34
- 108091040857 miR-604 stem-loop Proteins 0.000 description 29
- 230000001276 controlling effect Effects 0.000 description 25
- 241001465754 Metazoa Species 0.000 description 22
- 239000000575 pesticide Substances 0.000 description 22
- 239000003921 oil Substances 0.000 description 21
- 235000019198 oils Nutrition 0.000 description 21
- 108010016529 Bacillus amyloliquefaciens ribonuclease Proteins 0.000 description 19
- 229920002472 Starch Polymers 0.000 description 19
- 239000008107 starch Substances 0.000 description 19
- 235000019698 starch Nutrition 0.000 description 19
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 17
- 240000003768 Solanum lycopersicum Species 0.000 description 17
- 101710183938 Barstar Proteins 0.000 description 16
- 241000244206 Nematoda Species 0.000 description 16
- 241000709769 Potato leafroll virus Species 0.000 description 16
- 239000002689 soil Substances 0.000 description 16
- 235000006618 Brassica rapa subsp oleifera Nutrition 0.000 description 15
- 108091088140 miR162 stem-loop Proteins 0.000 description 14
- 241001301148 Brassica rapa subsp. oleifera Species 0.000 description 13
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 13
- DRSHXJFUUPIBHX-UHFFFAOYSA-N COc1ccc(cc1)N1N=CC2C=NC(Nc3cc(OC)c(OC)c(OCCCN4CCN(C)CC4)c3)=NC12 Chemical compound COc1ccc(cc1)N1N=CC2C=NC(Nc3cc(OC)c(OC)c(OCCCN4CCN(C)CC4)c3)=NC12 DRSHXJFUUPIBHX-UHFFFAOYSA-N 0.000 description 13
- 240000004658 Medicago sativa Species 0.000 description 11
- 230000015572 biosynthetic process Effects 0.000 description 11
- 239000005631 2,4-Dichlorophenoxyacetic acid Substances 0.000 description 10
- 235000009467 Carica papaya Nutrition 0.000 description 10
- 241000256248 Spodoptera Species 0.000 description 10
- 230000000692 anti-sense effect Effects 0.000 description 10
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 10
- 238000011282 treatment Methods 0.000 description 10
- 241000219310 Beta vulgaris subsp. vulgaris Species 0.000 description 9
- 235000014698 Brassica juncea var multisecta Nutrition 0.000 description 9
- 241000227653 Lycopersicon Species 0.000 description 9
- 235000002262 Lycopersicon Nutrition 0.000 description 9
- 235000017587 Medicago sativa ssp. sativa Nutrition 0.000 description 9
- 241000723762 Potato virus Y Species 0.000 description 9
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 9
- 235000005822 corn Nutrition 0.000 description 9
- 240000006432 Carica papaya Species 0.000 description 8
- 241001364932 Chrysodeixis Species 0.000 description 8
- 235000007542 Cichorium intybus Nutrition 0.000 description 8
- 244000061176 Nicotiana tabacum Species 0.000 description 8
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 8
- 244000046052 Phaseolus vulgaris Species 0.000 description 8
- 235000021536 Sugar beet Nutrition 0.000 description 8
- MNHVNIJQQRJYDH-UHFFFAOYSA-N 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione Chemical compound N1=CNC(=S)N1CC(C1(Cl)CC1)(O)CC1=CC=CC=C1Cl MNHVNIJQQRJYDH-UHFFFAOYSA-N 0.000 description 7
- 241000335053 Beta vulgaris Species 0.000 description 7
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 7
- 239000005825 Prothioconazole Substances 0.000 description 7
- 240000000111 Saccharum officinarum Species 0.000 description 7
- 235000007201 Saccharum officinarum Nutrition 0.000 description 7
- 235000002597 Solanum melongena Nutrition 0.000 description 7
- 244000061458 Solanum melongena Species 0.000 description 7
- 150000003839 salts Chemical class 0.000 description 7
- 240000008100 Brassica rapa Species 0.000 description 6
- 244000298479 Cichorium intybus Species 0.000 description 6
- 244000241257 Cucumis melo Species 0.000 description 6
- 235000009854 Cucurbita moschata Nutrition 0.000 description 6
- 240000001980 Cucurbita pepo Species 0.000 description 6
- 235000009852 Cucurbita pepo Nutrition 0.000 description 6
- 239000005807 Metalaxyl Substances 0.000 description 6
- 102000019315 Nicotinic acetylcholine receptors Human genes 0.000 description 6
- 108050006807 Nicotinic acetylcholine receptors Proteins 0.000 description 6
- 241000723990 Papaya ringspot virus Species 0.000 description 6
- 241000219000 Populus Species 0.000 description 6
- 230000009471 action Effects 0.000 description 6
- 235000013399 edible fruits Nutrition 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- ZQEIXNIJLIKNTD-UHFFFAOYSA-N methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate Chemical compound COCC(=O)N(C(C)C(=O)OC)C1=C(C)C=CC=C1C ZQEIXNIJLIKNTD-UHFFFAOYSA-N 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 6
- 241000894007 species Species 0.000 description 6
- 235000020354 squash Nutrition 0.000 description 6
- PXBFMLJZNCDSMP-UHFFFAOYSA-N 2-Aminobenzamide Chemical compound NC(=O)C1=CC=CC=C1N PXBFMLJZNCDSMP-UHFFFAOYSA-N 0.000 description 5
- RUXHWBMJNBBYNL-UHFFFAOYSA-N 3-hydroxy-1,2-dihydropyrrol-5-one Chemical class OC1=CC(=O)NC1 RUXHWBMJNBBYNL-UHFFFAOYSA-N 0.000 description 5
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 description 5
- 235000016068 Berberis vulgaris Nutrition 0.000 description 5
- 101100442689 Caenorhabditis elegans hdl-1 gene Proteins 0.000 description 5
- 244000025254 Cannabis sativa Species 0.000 description 5
- 239000005944 Chlorpyrifos Substances 0.000 description 5
- 241000208818 Helianthus Species 0.000 description 5
- 235000003222 Helianthus annuus Nutrition 0.000 description 5
- 241000255990 Helicoverpa Species 0.000 description 5
- 101150048253 PHYA gene Proteins 0.000 description 5
- 240000007377 Petunia x hybrida Species 0.000 description 5
- 239000005929 Spinetoram Substances 0.000 description 5
- GOENIMGKWNZVDA-OAMCMWGQSA-N Spinetoram Chemical compound CO[C@@H]1[C@H](OCC)[C@@H](OC)[C@H](C)O[C@H]1OC1C[C@H]2[C@@H]3C=C4C(=O)[C@H](C)[C@@H](O[C@@H]5O[C@H](C)[C@H](CC5)N(C)C)CCC[C@H](CC)OC(=O)CC4[C@@H]3CC[C@@H]2C1 GOENIMGKWNZVDA-OAMCMWGQSA-N 0.000 description 5
- 239000005664 Spirodiclofen Substances 0.000 description 5
- 239000005665 Spiromesifen Substances 0.000 description 5
- 239000005931 Spirotetramat Substances 0.000 description 5
- YASYVMFAVPKPKE-UHFFFAOYSA-N acephate Chemical compound COP(=O)(SC)NC(C)=O YASYVMFAVPKPKE-UHFFFAOYSA-N 0.000 description 5
- DUEPRVBVGDRKAG-UHFFFAOYSA-N carbofuran Chemical compound CNC(=O)OC1=CC=CC2=C1OC(C)(C)C2 DUEPRVBVGDRKAG-UHFFFAOYSA-N 0.000 description 5
- SBPBAQFWLVIOKP-UHFFFAOYSA-N chlorpyrifos Chemical compound CCOP(=S)(OCC)OC1=NC(Cl)=C(Cl)C=C1Cl SBPBAQFWLVIOKP-UHFFFAOYSA-N 0.000 description 5
- 101150081158 crtB gene Proteins 0.000 description 5
- 230000002438 mitochondrial effect Effects 0.000 description 5
- PEQJBOMPGWYIRO-UHFFFAOYSA-N n-ethyl-3,4-dimethoxyaniline Chemical compound CCNC1=CC=C(OC)C(OC)=C1 PEQJBOMPGWYIRO-UHFFFAOYSA-N 0.000 description 5
- 235000012015 potatoes Nutrition 0.000 description 5
- 238000011160 research Methods 0.000 description 5
- DTDSAWVUFPGDMX-UHFFFAOYSA-N spirodiclofen Chemical compound CCC(C)(C)C(=O)OC1=C(C=2C(=CC(Cl)=CC=2)Cl)C(=O)OC11CCCCC1 DTDSAWVUFPGDMX-UHFFFAOYSA-N 0.000 description 5
- GOLXNESZZPUPJE-UHFFFAOYSA-N spiromesifen Chemical compound CC1=CC(C)=CC(C)=C1C(C(O1)=O)=C(OC(=O)CC(C)(C)C)C11CCCC1 GOLXNESZZPUPJE-UHFFFAOYSA-N 0.000 description 5
- CLSVJBIHYWPGQY-GGYDESQDSA-N spirotetramat Chemical compound CCOC(=O)OC1=C(C=2C(=CC=C(C)C=2)C)C(=O)N[C@@]11CC[C@H](OC)CC1 CLSVJBIHYWPGQY-GGYDESQDSA-N 0.000 description 5
- 235000013311 vegetables Nutrition 0.000 description 5
- WEQPBCSPRXFQQS-UHFFFAOYSA-N 4,5-dihydro-1,2-oxazole Chemical compound C1CC=NO1 WEQPBCSPRXFQQS-UHFFFAOYSA-N 0.000 description 4
- 241000625753 Anticarsia Species 0.000 description 4
- 241000238421 Arthropoda Species 0.000 description 4
- 235000011292 Brassica rapa Nutrition 0.000 description 4
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 4
- 101100169274 Escherichia coli (strain K12) cydC gene Proteins 0.000 description 4
- 241000237858 Gastropoda Species 0.000 description 4
- 101100420606 Geobacillus stearothermophilus sacB gene Proteins 0.000 description 4
- 241000022569 Hemeroblemma Species 0.000 description 4
- 240000006240 Linum usitatissimum Species 0.000 description 4
- 235000004431 Linum usitatissimum Nutrition 0.000 description 4
- 235000010624 Medicago sativa Nutrition 0.000 description 4
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 description 4
- 239000005934 Sulfoxaflor Substances 0.000 description 4
- 241000482268 Zea mays subsp. mays Species 0.000 description 4
- 101100339555 Zymoseptoria tritici HPPD gene Proteins 0.000 description 4
- ZVQOOHYFBIDMTQ-UHFFFAOYSA-N [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide Chemical compound N#CN=S(C)(=O)C(C)C1=CC=C(C(F)(F)F)N=C1 ZVQOOHYFBIDMTQ-UHFFFAOYSA-N 0.000 description 4
- 235000013339 cereals Nutrition 0.000 description 4
- 101150049887 cspB gene Proteins 0.000 description 4
- 101150041068 cspJ gene Proteins 0.000 description 4
- 101150010904 cspLB gene Proteins 0.000 description 4
- GCKZANITAMOIAR-XWVCPFKXSA-N dsstox_cid_14566 Chemical compound [O-]C(=O)C1=CC=CC=C1.C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H]([NH2+]C)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 GCKZANITAMOIAR-XWVCPFKXSA-N 0.000 description 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 4
- QOIYTRGFOFZNKF-UHFFFAOYSA-N flupyradifurone Chemical compound C=1C(=O)OCC=1N(CC(F)F)CC1=CC=C(Cl)N=C1 QOIYTRGFOFZNKF-UHFFFAOYSA-N 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- MIOBBYRMXGNORL-UHFFFAOYSA-N pyrifluquinazon Chemical compound C1C2=CC(C(F)(C(F)(F)F)C(F)(F)F)=CC=C2N(C(=O)C)C(=O)N1NCC1=CC=CN=C1 MIOBBYRMXGNORL-UHFFFAOYSA-N 0.000 description 4
- 239000003053 toxin Substances 0.000 description 4
- 231100000765 toxin Toxicity 0.000 description 4
- 108700012359 toxins Proteins 0.000 description 4
- ZCVAOQKBXKSDMS-PVAVHDDUSA-N (+)-trans-(S)-allethrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)O[C@@H]1C(C)=C(CC=C)C(=O)C1 ZCVAOQKBXKSDMS-PVAVHDDUSA-N 0.000 description 3
- JWDYCNIAQWPBHD-UHFFFAOYSA-N 1-(2-methylphenyl)glycerol Chemical compound CC1=CC=CC=C1OCC(O)CO JWDYCNIAQWPBHD-UHFFFAOYSA-N 0.000 description 3
- PXMNMQRDXWABCY-UHFFFAOYSA-N 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Chemical compound C1=NC=NN1CC(O)(C(C)(C)C)CCC1=CC=C(Cl)C=C1 PXMNMQRDXWABCY-UHFFFAOYSA-N 0.000 description 3
- WKBPZYKAUNRMKP-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)pentyl]1,2,4-triazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(CCC)CN1C=NC=N1 WKBPZYKAUNRMKP-UHFFFAOYSA-N 0.000 description 3
- HRUHMMAFOLUCDX-UHFFFAOYSA-N 2-(3-chloropyridin-2-yl)-n-[2,4-dichloro-6-[(diethyl-$l^{4}-sulfanylidene)carbamoyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide Chemical compound CCS(CC)=NC(=O)C1=CC(Cl)=CC(Cl)=C1NC(=O)C1=CC(C(F)(F)F)=NN1C1=NC=CC=C1Cl HRUHMMAFOLUCDX-UHFFFAOYSA-N 0.000 description 3
- 108010020183 3-phosphoshikimate 1-carboxyvinyltransferase Proteins 0.000 description 3
- LHZOTJOOBRODLL-UHFFFAOYSA-N 4-oxo-1-(pyrimidin-5-ylmethyl)-3-[3-(trifluoromethyl)phenyl]pyrido[1,2-a]pyrimidin-5-ium-2-olate Chemical compound O=C1[N+]2=CC=CC=C2N(CC=2C=NC=NC=2)C([O-])=C1C1=CC=CC(C(F)(F)F)=C1 LHZOTJOOBRODLL-UHFFFAOYSA-N 0.000 description 3
- 241000239223 Arachnida Species 0.000 description 3
- 241001166626 Aulacorthum solani Species 0.000 description 3
- 244000075850 Avena orientalis Species 0.000 description 3
- 235000007319 Avena orientalis Nutrition 0.000 description 3
- 101100497223 Bacillus thuringiensis cry1Ag gene Proteins 0.000 description 3
- 241000702286 Bean golden mosaic virus Species 0.000 description 3
- 240000007124 Brassica oleracea Species 0.000 description 3
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 3
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 3
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 3
- 240000004160 Capsicum annuum Species 0.000 description 3
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 description 3
- 229920002101 Chitin Polymers 0.000 description 3
- 240000008067 Cucumis sativus Species 0.000 description 3
- 241001645342 Diaporthe citri Species 0.000 description 3
- 239000005504 Dicamba Substances 0.000 description 3
- 101100326341 Drosophila melanogaster brun gene Proteins 0.000 description 3
- 102000015782 Electron Transport Complex III Human genes 0.000 description 3
- 108010024882 Electron Transport Complex III Proteins 0.000 description 3
- 235000007340 Hordeum vulgare Nutrition 0.000 description 3
- 240000005979 Hordeum vulgare Species 0.000 description 3
- 240000004322 Lens culinaris Species 0.000 description 3
- 235000014647 Lens culinaris subsp culinaris Nutrition 0.000 description 3
- 241000228457 Leptosphaeria maculans Species 0.000 description 3
- 239000005820 Prochloraz Substances 0.000 description 3
- 241000201375 Radopholus similis Species 0.000 description 3
- 241000746444 Saccharum sp. Species 0.000 description 3
- 241000209056 Secale Species 0.000 description 3
- 235000007238 Secale cereale Nutrition 0.000 description 3
- 108010052164 Sodium Channels Proteins 0.000 description 3
- 102000018674 Sodium Channels Human genes 0.000 description 3
- 239000005839 Tebuconazole Substances 0.000 description 3
- 241001310178 Watermelon mosaic virus Species 0.000 description 3
- 230000036579 abiotic stress Effects 0.000 description 3
- 239000000642 acaricide Substances 0.000 description 3
- 235000001014 amino acid Nutrition 0.000 description 3
- 229940024606 amino acid Drugs 0.000 description 3
- VEMKTZHHVJILDY-UXHICEINSA-N bioresmethrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OCC1=COC(CC=2C=CC=CC=2)=C1 VEMKTZHHVJILDY-UXHICEINSA-N 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 230000035613 defoliation Effects 0.000 description 3
- PGRHXDWITVMQBC-UHFFFAOYSA-N dehydroacetic acid Natural products CC(=O)C1C(=O)OC(C)=CC1=O PGRHXDWITVMQBC-UHFFFAOYSA-N 0.000 description 3
- IWEDIXLBFLAXBO-UHFFFAOYSA-N dicamba Chemical compound COC1=C(Cl)C=CC(Cl)=C1C(O)=O IWEDIXLBFLAXBO-UHFFFAOYSA-N 0.000 description 3
- 238000010410 dusting Methods 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- NYPJDWWKZLNGGM-UHFFFAOYSA-N fenvalerate Aalpha Natural products C=1C=C(Cl)C=CC=1C(C(C)C)C(=O)OC(C#N)C(C=1)=CC=CC=1OC1=CC=CC=C1 NYPJDWWKZLNGGM-UHFFFAOYSA-N 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 229920005610 lignin Polymers 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 239000005645 nematicide Substances 0.000 description 3
- 239000003016 pheromone Substances 0.000 description 3
- 230000010152 pollination Effects 0.000 description 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 3
- TVLSRXXIMLFWEO-UHFFFAOYSA-N prochloraz Chemical compound C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl TVLSRXXIMLFWEO-UHFFFAOYSA-N 0.000 description 3
- 235000018102 proteins Nutrition 0.000 description 3
- 229940044601 receptor agonist Drugs 0.000 description 3
- 239000000018 receptor agonist Substances 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- ZMYFCFLJBGAQRS-IRXDYDNUSA-N (2R,3S)-epoxiconazole Chemical compound C1=CC(F)=CC=C1[C@@]1(CN2N=CN=C2)[C@H](C=2C(=CC=CC=2)Cl)O1 ZMYFCFLJBGAQRS-IRXDYDNUSA-N 0.000 description 2
- RYAUSSKQMZRMAI-ALOPSCKCSA-N (2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Chemical compound C=1C=C(C(C)(C)C)C=CC=1CC(C)CN1C[C@H](C)O[C@H](C)C1 RYAUSSKQMZRMAI-ALOPSCKCSA-N 0.000 description 2
- QNBTYORWCCMPQP-JXAWBTAJSA-N (Z)-dimethomorph Chemical compound C1=C(OC)C(OC)=CC=C1C(\C=1C=CC(Cl)=CC=1)=C/C(=O)N1CCOCC1 QNBTYORWCCMPQP-JXAWBTAJSA-N 0.000 description 2
- JWUCHKBSVLQQCO-UHFFFAOYSA-N 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Chemical compound C=1C=C(F)C=CC=1C(C=1C(=CC=CC=1)F)(O)CN1C=NC=N1 JWUCHKBSVLQQCO-UHFFFAOYSA-N 0.000 description 2
- PFFIDZXUXFLSSR-UHFFFAOYSA-N 1-methyl-N-[2-(4-methylpentan-2-yl)-3-thienyl]-3-(trifluoromethyl)pyrazole-4-carboxamide Chemical compound S1C=CC(NC(=O)C=2C(=NN(C)C=2)C(F)(F)F)=C1C(C)CC(C)C PFFIDZXUXFLSSR-UHFFFAOYSA-N 0.000 description 2
- YTOPFCCWCSOHFV-UHFFFAOYSA-N 2,6-dimethyl-4-tridecylmorpholine Chemical compound CCCCCCCCCCCCCN1CC(C)OC(C)C1 YTOPFCCWCSOHFV-UHFFFAOYSA-N 0.000 description 2
- WCGDPGWTTSEEBS-UHFFFAOYSA-N 2-(3-chloropyridin-2-yl)-n-[2,4-dibromo-6-[(diethyl-$l^{4}-sulfanylidene)carbamoyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide Chemical compound CCS(CC)=NC(=O)C1=CC(Br)=CC(Br)=C1NC(=O)C1=CC(C(F)(F)F)=NN1C1=NC=CC=C1Cl WCGDPGWTTSEEBS-UHFFFAOYSA-N 0.000 description 2
- WNZQDUSMALZDQF-UHFFFAOYSA-N 2-benzofuran-1(3H)-one Chemical compound C1=CC=C2C(=O)OCC2=C1 WNZQDUSMALZDQF-UHFFFAOYSA-N 0.000 description 2
- XTDZGXBTXBEZDN-UHFFFAOYSA-N 3-(difluoromethyl)-N-(9-isopropyl-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl)-1-methylpyrazole-4-carboxamide Chemical compound CC(C)C1C2CCC1C1=C2C=CC=C1NC(=O)C1=CN(C)N=C1C(F)F XTDZGXBTXBEZDN-UHFFFAOYSA-N 0.000 description 2
- ONILAONOGQYBHW-UHFFFAOYSA-N 5-bromo-n-[2,4-dichloro-6-(methylcarbamoyl)phenyl]-2-(3,5-dichloropyridin-2-yl)pyrazole-3-carboxamide Chemical compound CNC(=O)C1=CC(Cl)=CC(Cl)=C1NC(=O)C1=CC(Br)=NN1C1=NC=C(Cl)C=C1Cl ONILAONOGQYBHW-UHFFFAOYSA-N 0.000 description 2
- ZCTRJEAOSGAHTA-UHFFFAOYSA-N 5-chloro-2-(3-chloropyridin-2-yl)-n-[2,4-dichloro-6-(2-cyanopropan-2-ylcarbamoyl)phenyl]pyrazole-3-carboxamide Chemical compound N#CC(C)(C)NC(=O)C1=CC(Cl)=CC(Cl)=C1NC(=O)C1=CC(Cl)=NN1C1=NC=CC=C1Cl ZCTRJEAOSGAHTA-UHFFFAOYSA-N 0.000 description 2
- GOFJDXZZHFNFLV-UHFFFAOYSA-N 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide Chemical compound CC(C)CC(C)C1=CC=CC=C1NC(=O)C1=C(F)N(C)N=C1C GOFJDXZZHFNFLV-UHFFFAOYSA-N 0.000 description 2
- PCCSBWNGDMYFCW-UHFFFAOYSA-N 5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione Chemical compound O=C1C(C)(C=2C=CC(OC=3C=CC=CC=3)=CC=2)OC(=O)N1NC1=CC=CC=C1 PCCSBWNGDMYFCW-UHFFFAOYSA-N 0.000 description 2
- 229940124596 AChE inhibitor Drugs 0.000 description 2
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 description 2
- 102000000452 Acetyl-CoA carboxylase Human genes 0.000 description 2
- 108010016219 Acetyl-CoA carboxylase Proteins 0.000 description 2
- 240000007241 Agrostis stolonifera Species 0.000 description 2
- 241000218475 Agrotis segetum Species 0.000 description 2
- 241000234282 Allium Species 0.000 description 2
- 235000005254 Allium ampeloprasum Nutrition 0.000 description 2
- 240000006108 Allium ampeloprasum Species 0.000 description 2
- 235000002732 Allium cepa var. cepa Nutrition 0.000 description 2
- 240000002234 Allium sativum Species 0.000 description 2
- 241001470771 Athous haemorrhoidalis Species 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000726102 Atta cephalotes Species 0.000 description 2
- 235000000832 Ayote Nutrition 0.000 description 2
- 241000193747 Bacillus firmus Species 0.000 description 2
- 241001109971 Bactericera cockerelli Species 0.000 description 2
- 241000580218 Belonolaimus longicaudatus Species 0.000 description 2
- 241000254123 Bemisia Species 0.000 description 2
- 241000254127 Bemisia tabaci Species 0.000 description 2
- 235000021533 Beta vulgaris Nutrition 0.000 description 2
- 108010018763 Biotin carboxylase Proteins 0.000 description 2
- 239000005738 Bixafen Substances 0.000 description 2
- 239000005740 Boscalid Substances 0.000 description 2
- 241000273318 Brachycaudus cardui Species 0.000 description 2
- 241000219198 Brassica Species 0.000 description 2
- 235000005637 Brassica campestris Nutrition 0.000 description 2
- 241000244036 Brugia Species 0.000 description 2
- 241000243771 Bursaphelenchus xylophilus Species 0.000 description 2
- 241000726760 Cadra cautella Species 0.000 description 2
- 241000257163 Calliphora vicina Species 0.000 description 2
- 241001350371 Capua Species 0.000 description 2
- TWFZGCMQGLPBSX-UHFFFAOYSA-N Carbendazim Natural products C1=CC=C2NC(NC(=O)OC)=NC2=C1 TWFZGCMQGLPBSX-UHFFFAOYSA-N 0.000 description 2
- 229940127437 Chloride Channel Antagonists Drugs 0.000 description 2
- 239000005747 Chlorothalonil Substances 0.000 description 2
- 241001525905 Choristoneura murinana Species 0.000 description 2
- 241001124179 Chrysops Species 0.000 description 2
- 241000723343 Cichorium Species 0.000 description 2
- 241000098277 Cnaphalocrocis Species 0.000 description 2
- 241000202814 Cochliomyia hominivorax Species 0.000 description 2
- 240000007154 Coffea arabica Species 0.000 description 2
- 241001094913 Cryptomyzus Species 0.000 description 2
- 235000009842 Cucumis melo Nutrition 0.000 description 2
- 235000009849 Cucumis sativus Nutrition 0.000 description 2
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 description 2
- 241000219104 Cucurbitaceae Species 0.000 description 2
- 235000002767 Daucus carota Nutrition 0.000 description 2
- 244000000626 Daucus carota Species 0.000 description 2
- 241001609607 Delia platura Species 0.000 description 2
- 241000832201 Diaphania Species 0.000 description 2
- 239000005761 Dimethomorph Substances 0.000 description 2
- 208000035240 Disease Resistance Diseases 0.000 description 2
- 239000005764 Dithianon Substances 0.000 description 2
- 241000399949 Ditylenchus dipsaci Species 0.000 description 2
- 239000005765 Dodemorph Substances 0.000 description 2
- 235000001950 Elaeis guineensis Nutrition 0.000 description 2
- 241000122098 Ephestia kuehniella Species 0.000 description 2
- 239000005767 Epoxiconazole Substances 0.000 description 2
- 241001558857 Eriophyes Species 0.000 description 2
- FNELVJVBIYMIMC-UHFFFAOYSA-N Ethiprole Chemical compound N1=C(C#N)C(S(=O)CC)=C(N)N1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl FNELVJVBIYMIMC-UHFFFAOYSA-N 0.000 description 2
- 239000005897 Etoxazole Substances 0.000 description 2
- 244000004281 Eucalyptus maculata Species 0.000 description 2
- 241000060469 Eupoecilia ambiguella Species 0.000 description 2
- 239000005772 Famoxadone Substances 0.000 description 2
- 239000005778 Fenpropimorph Substances 0.000 description 2
- 239000005783 Fluopyram Substances 0.000 description 2
- 239000005785 Fluquinconazole Substances 0.000 description 2
- 239000005787 Flutriafol Substances 0.000 description 2
- 241000208152 Geranium Species 0.000 description 2
- 235000004341 Gossypium herbaceum Nutrition 0.000 description 2
- 240000002024 Gossypium herbaceum Species 0.000 description 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 description 2
- 241000255967 Helicoverpa zea Species 0.000 description 2
- 241000256244 Heliothis virescens Species 0.000 description 2
- 241001581044 Hellula undalis Species 0.000 description 2
- 241000258937 Hemiptera Species 0.000 description 2
- 241000498254 Heterodera glycines Species 0.000 description 2
- 241001503238 Homalodisca vitripennis Species 0.000 description 2
- 241000257303 Hymenoptera Species 0.000 description 2
- 241000370523 Hypena scabra Species 0.000 description 2
- 241001495448 Impatiens <genus> Species 0.000 description 2
- 239000005907 Indoxacarb Substances 0.000 description 2
- 206010021929 Infertility male Diseases 0.000 description 2
- 235000010702 Insulata Nutrition 0.000 description 2
- 244000165077 Insulata Species 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 239000005799 Isopyrazam Substances 0.000 description 2
- 241001533590 Junonia Species 0.000 description 2
- 241000540210 Leucoptera coffeella Species 0.000 description 2
- 241000673175 Limonius californicus Species 0.000 description 2
- 241001646976 Linepithema humile Species 0.000 description 2
- 241000193386 Lysinibacillus sphaericus Species 0.000 description 2
- 208000007466 Male Infertility Diseases 0.000 description 2
- 239000005802 Mancozeb Substances 0.000 description 2
- 241000219823 Medicago Species 0.000 description 2
- 241000243785 Meloidogyne javanica Species 0.000 description 2
- 239000005868 Metconazole Substances 0.000 description 2
- 239000005916 Methomyl Substances 0.000 description 2
- 239000005809 Metiram Substances 0.000 description 2
- 239000005810 Metrafenone Substances 0.000 description 2
- 241001469521 Mocis latipes Species 0.000 description 2
- 241000555285 Monomorium Species 0.000 description 2
- 240000005561 Musa balbisiana Species 0.000 description 2
- 241001477931 Mythimna unipuncta Species 0.000 description 2
- 241000512856 Myzus ascalonicus Species 0.000 description 2
- XQJQCBDIXRIYRP-UHFFFAOYSA-N N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1pyrazole-4-carboxamide Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=CC=C1C1C(C2CC2)C1 XQJQCBDIXRIYRP-UHFFFAOYSA-N 0.000 description 2
- 241000194215 Neomegalotomus parvus Species 0.000 description 2
- 241000488557 Oligonychus Species 0.000 description 2
- 241001012098 Omiodes indicata Species 0.000 description 2
- 241001491877 Operophtera brumata Species 0.000 description 2
- 241001160353 Oulema melanopus Species 0.000 description 2
- 241001570894 Oulema oryzae Species 0.000 description 2
- 241001143330 Paratrichodorus minor Species 0.000 description 2
- 241001523670 Parcoblatta pensylvanica Species 0.000 description 2
- 206010034133 Pathogen resistance Diseases 0.000 description 2
- 241000517306 Pediculus humanus corporis Species 0.000 description 2
- 241000208181 Pelargonium Species 0.000 description 2
- 239000005815 Penflufen Substances 0.000 description 2
- 239000005816 Penthiopyrad Substances 0.000 description 2
- 244000025272 Persea americana Species 0.000 description 2
- 241001227717 Phyllopertha horticola Species 0.000 description 2
- 235000010582 Pisum sativum Nutrition 0.000 description 2
- 240000004713 Pisum sativum Species 0.000 description 2
- 241000500437 Plutella xylostella Species 0.000 description 2
- 241000218979 Populus sp. Species 0.000 description 2
- 239000005824 Proquinazid Substances 0.000 description 2
- 241000526145 Psylla Species 0.000 description 2
- 241001180370 Psylliodes chrysocephalus Species 0.000 description 2
- 239000005828 Pyrimethanil Substances 0.000 description 2
- 241001481703 Rhipicephalus <genus> Species 0.000 description 2
- 240000000528 Ricinus communis Species 0.000 description 2
- 241000220317 Rosa Species 0.000 description 2
- 235000002315 Rosa hybrid cultivar Nutrition 0.000 description 2
- 244000037691 Rosa hybrida Species 0.000 description 2
- 241000702971 Rotylenchulus reniformis Species 0.000 description 2
- 239000005834 Sedaxane Substances 0.000 description 2
- 241000180219 Sitobion avenae Species 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 241001414853 Spissistilus festinus Species 0.000 description 2
- 241001161749 Stenchaetothrips biformis Species 0.000 description 2
- 229930182558 Sterol Natural products 0.000 description 2
- 244000228451 Stevia rebaudiana Species 0.000 description 2
- 241000098292 Striacosta albicosta Species 0.000 description 2
- 241001454293 Tetranychus urticae Species 0.000 description 2
- 229920002359 Tetronic® Polymers 0.000 description 2
- 241001231950 Thaumetopoea pityocampa Species 0.000 description 2
- 102000005488 Thioesterase Human genes 0.000 description 2
- 239000005843 Thiram Substances 0.000 description 2
- 241000243774 Trichinella Species 0.000 description 2
- 239000005857 Trifloxystrobin Substances 0.000 description 2
- 241000402796 Tylenchorhynchus claytoni Species 0.000 description 2
- 241001267621 Tylenchulus semipenetrans Species 0.000 description 2
- 241001351286 Udea rubigalis Species 0.000 description 2
- 235000004031 Viola x wittrockiana Nutrition 0.000 description 2
- 241000219094 Vitaceae Species 0.000 description 2
- 241000723854 Zucchini yellow mosaic virus Species 0.000 description 2
- 230000000895 acaricidal effect Effects 0.000 description 2
- 239000012190 activator Substances 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 239000012872 agrochemical composition Substances 0.000 description 2
- 150000001350 alkyl halides Chemical class 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 230000003281 allosteric effect Effects 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 229940005348 bacillus firmus Drugs 0.000 description 2
- 229940097012 bacillus thuringiensis Drugs 0.000 description 2
- 235000021015 bananas Nutrition 0.000 description 2
- CJPQIRJHIZUAQP-MRXNPFEDSA-N benalaxyl-M Chemical compound CC=1C=CC=C(C)C=1N([C@H](C)C(=O)OC)C(=O)CC1=CC=CC=C1 CJPQIRJHIZUAQP-MRXNPFEDSA-N 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- FYZBOYWSHKHDMT-UHFFFAOYSA-N benfuracarb Chemical compound CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C)(C)C2 FYZBOYWSHKHDMT-UHFFFAOYSA-N 0.000 description 2
- RIOXQFHNBCKOKP-UHFFFAOYSA-N benomyl Chemical compound C1=CC=C2N(C(=O)NCCCC)C(NC(=O)OC)=NC2=C1 RIOXQFHNBCKOKP-UHFFFAOYSA-N 0.000 description 2
- MITFXPHMIHQXPI-UHFFFAOYSA-N benzoxaprofen Natural products N=1C2=CC(C(C(O)=O)C)=CC=C2OC=1C1=CC=C(Cl)C=C1 MITFXPHMIHQXPI-UHFFFAOYSA-N 0.000 description 2
- 229960001901 bioallethrin Drugs 0.000 description 2
- LDLMOOXUCMHBMZ-UHFFFAOYSA-N bixafen Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=C(F)C=C1C1=CC=C(Cl)C(Cl)=C1 LDLMOOXUCMHBMZ-UHFFFAOYSA-N 0.000 description 2
- 229940118790 boscalid Drugs 0.000 description 2
- WYEMLYFITZORAB-UHFFFAOYSA-N boscalid Chemical compound C1=CC(Cl)=CC=C1C1=CC=CC=C1NC(=O)C1=CC=CN=C1Cl WYEMLYFITZORAB-UHFFFAOYSA-N 0.000 description 2
- GZUXJHMPEANEGY-UHFFFAOYSA-N bromomethane Chemical compound BrC GZUXJHMPEANEGY-UHFFFAOYSA-N 0.000 description 2
- NLKUPINTOLSSLD-UHFFFAOYSA-L calcium;4-(1-oxidopropylidene)-3,5-dioxocyclohexane-1-carboxylate Chemical compound [Ca+2].CCC([O-])=C1C(=O)CC(C([O-])=O)CC1=O NLKUPINTOLSSLD-UHFFFAOYSA-L 0.000 description 2
- 150000004657 carbamic acid derivatives Chemical class 0.000 description 2
- 239000006013 carbendazim Substances 0.000 description 2
- JNPZQRQPIHJYNM-UHFFFAOYSA-N carbendazim Chemical compound C1=C[CH]C2=NC(NC(=O)OC)=NC2=C1 JNPZQRQPIHJYNM-UHFFFAOYSA-N 0.000 description 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 2
- 230000032823 cell division Effects 0.000 description 2
- NDHXMRFNYMNBKO-PWSUYJOCSA-N chembl2227757 Chemical compound [O-][N+](=O)C([C@H]1CC[C@H](O1)N1CC2)=C1N2CC1=CC=C(Cl)N=C1 NDHXMRFNYMNBKO-PWSUYJOCSA-N 0.000 description 2
- 239000003467 chloride channel stimulating agent Substances 0.000 description 2
- CRQQGFGUEAVUIL-UHFFFAOYSA-N chlorothalonil Chemical compound ClC1=C(Cl)C(C#N)=C(Cl)C(C#N)=C1Cl CRQQGFGUEAVUIL-UHFFFAOYSA-N 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 235000016213 coffee Nutrition 0.000 description 2
- 235000013353 coffee beverage Nutrition 0.000 description 2
- 244000038559 crop plants Species 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- NNRSYETYEADPBW-UHFFFAOYSA-N cyhalodiamide Chemical compound CC1=CC(C(F)(C(F)(F)F)C(F)(F)F)=CC=C1NC(=O)C1=CC=CC(Cl)=C1C(=O)NC(C)(C)C#N NNRSYETYEADPBW-UHFFFAOYSA-N 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- OEBRKCOSUFCWJD-UHFFFAOYSA-N dichlorvos Chemical compound COP(=O)(OC)OC=C(Cl)Cl OEBRKCOSUFCWJD-UHFFFAOYSA-N 0.000 description 2
- FBOUIAKEJMZPQG-BLXFFLACSA-N diniconazole-M Chemical compound C1=NC=NN1/C([C@H](O)C(C)(C)C)=C/C1=CC=C(Cl)C=C1Cl FBOUIAKEJMZPQG-BLXFFLACSA-N 0.000 description 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 2
- PYZSVQVRHDXQSL-UHFFFAOYSA-N dithianon Chemical compound S1C(C#N)=C(C#N)SC2=C1C(=O)C1=CC=CC=C1C2=O PYZSVQVRHDXQSL-UHFFFAOYSA-N 0.000 description 2
- JMXKCYUTURMERF-UHFFFAOYSA-N dodemorph Chemical compound C1C(C)OC(C)CN1C1CCCCCCCCCCC1 JMXKCYUTURMERF-UHFFFAOYSA-N 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 231100000290 environmental risk assessment Toxicity 0.000 description 2
- IXSZQYVWNJNRAL-UHFFFAOYSA-N etoxazole Chemical compound CCOC1=CC(C(C)(C)C)=CC=C1C1N=C(C=2C(=CC=CC=2F)F)OC1 IXSZQYVWNJNRAL-UHFFFAOYSA-N 0.000 description 2
- YYJNOYZRYGDPNH-MFKUBSTISA-N fenpyroximate Chemical compound C=1C=C(C(=O)OC(C)(C)C)C=CC=1CO/N=C/C=1C(C)=NN(C)C=1OC1=CC=CC=C1 YYJNOYZRYGDPNH-MFKUBSTISA-N 0.000 description 2
- BFWMWWXRWVJXSE-UHFFFAOYSA-M fentin hydroxide Chemical class C=1C=CC=CC=1[Sn](C=1C=CC=CC=1)(O)C1=CC=CC=C1 BFWMWWXRWVJXSE-UHFFFAOYSA-M 0.000 description 2
- KVDJTXBXMWJJEF-UHFFFAOYSA-N fluopyram Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CCNC(=O)C1=CC=CC=C1C(F)(F)F KVDJTXBXMWJJEF-UHFFFAOYSA-N 0.000 description 2
- IJJVMEJXYNJXOJ-UHFFFAOYSA-N fluquinconazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1N1C(=O)C2=CC(F)=CC=C2N=C1N1C=NC=N1 IJJVMEJXYNJXOJ-UHFFFAOYSA-N 0.000 description 2
- FQKUGOMFVDPBIZ-UHFFFAOYSA-N flusilazole Chemical compound C=1C=C(F)C=CC=1[Si](C=1C=CC(F)=CC=1)(C)CN1C=NC=N1 FQKUGOMFVDPBIZ-UHFFFAOYSA-N 0.000 description 2
- GNVDAZSPJWCIQZ-UHFFFAOYSA-N flusulfamide Chemical compound ClC1=CC([N+](=O)[O-])=CC=C1NS(=O)(=O)C1=CC=C(Cl)C(C(F)(F)F)=C1 GNVDAZSPJWCIQZ-UHFFFAOYSA-N 0.000 description 2
- 235000004611 garlic Nutrition 0.000 description 2
- 235000021021 grapes Nutrition 0.000 description 2
- 239000003966 growth inhibitor Substances 0.000 description 2
- RONFGUROBZGJKP-UHFFFAOYSA-N iminoctadine Chemical compound NC(N)=NCCCCCCCCNCCCCCCCCN=C(N)N RONFGUROBZGJKP-UHFFFAOYSA-N 0.000 description 2
- 229930190166 impatien Natural products 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- VBCVPMMZEGZULK-NRFANRHFSA-N indoxacarb Chemical compound C([C@@]1(OC2)C(=O)OC)C3=CC(Cl)=CC=C3C1=NN2C(=O)N(C(=O)OC)C1=CC=C(OC(F)(F)F)C=C1 VBCVPMMZEGZULK-NRFANRHFSA-N 0.000 description 2
- 229930014550 juvenile hormone Natural products 0.000 description 2
- 239000002949 juvenile hormone Substances 0.000 description 2
- 150000003633 juvenile hormone derivatives Chemical class 0.000 description 2
- YKSNLCVSTHTHJA-UHFFFAOYSA-L maneb Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S YKSNLCVSTHTHJA-UHFFFAOYSA-L 0.000 description 2
- 229920000940 maneb Polymers 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- XWPZUHJBOLQNMN-UHFFFAOYSA-N metconazole Chemical compound C1=NC=NN1CC1(O)C(C)(C)CCC1CC1=CC=C(Cl)C=C1 XWPZUHJBOLQNMN-UHFFFAOYSA-N 0.000 description 2
- UHXUZOCRWCRNSJ-QPJJXVBHSA-N methomyl Chemical compound CNC(=O)O\N=C(/C)SC UHXUZOCRWCRNSJ-QPJJXVBHSA-N 0.000 description 2
- 229920000257 metiram Polymers 0.000 description 2
- AMSPWOYQQAWRRM-UHFFFAOYSA-N metrafenone Chemical compound COC1=CC=C(Br)C(C)=C1C(=O)C1=C(C)C=C(OC)C(OC)=C1OC AMSPWOYQQAWRRM-UHFFFAOYSA-N 0.000 description 2
- ZLBGSRMUSVULIE-GSMJGMFJSA-N milbemycin A3 Chemical class O1[C@H](C)[C@@H](C)CC[C@@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 ZLBGSRMUSVULIE-GSMJGMFJSA-N 0.000 description 2
- FMDLTPBLTVHTIM-UHFFFAOYSA-N n-[2-(5-amino-1,3,4-thiadiazol-2-yl)-4-chloro-6-methylphenyl]-5-bromo-2-(3-chloropyridin-2-yl)pyrazole-3-carboxamide Chemical compound C=1C(Br)=NN(C=2C(=CC=CN=2)Cl)C=1C(=O)NC=1C(C)=CC(Cl)=CC=1C1=NN=C(N)S1 FMDLTPBLTVHTIM-UHFFFAOYSA-N 0.000 description 2
- UWKQSUQMFIRFMM-UHFFFAOYSA-N n-[2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl]-2-(3-chloropyridin-2-yl)-5-(fluoromethoxy)pyrazole-3-carboxamide Chemical compound CC1=CC(Cl)=CC(C(=O)NC(C)(C)C)=C1NC(=O)C1=CC(OCF)=NN1C1=NC=CC=C1Cl UWKQSUQMFIRFMM-UHFFFAOYSA-N 0.000 description 2
- MNTIJQCNHWYBBK-UHFFFAOYSA-N n-methylsulfonyl-6-(2-pyridin-3-yl-1,3-thiazol-5-yl)pyridine-2-carboxamide Chemical compound CS(=O)(=O)NC(=O)C1=CC=CC(C=2SC(=NC=2)C=2C=NC=CC=2)=N1 MNTIJQCNHWYBBK-UHFFFAOYSA-N 0.000 description 2
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Chemical compound CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 2
- 239000003865 nucleic acid synthesis inhibitor Substances 0.000 description 2
- 235000014571 nuts Nutrition 0.000 description 2
- 150000004045 organic chlorine compounds Chemical class 0.000 description 2
- 230000010627 oxidative phosphorylation Effects 0.000 description 2
- 230000003071 parasitic effect Effects 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 150000003904 phospholipids Chemical class 0.000 description 2
- 229910000073 phosphorus hydride Inorganic materials 0.000 description 2
- NAYYNDKKHOIIOD-UHFFFAOYSA-N phthalamide Chemical class NC(=O)C1=CC=CC=C1C(N)=O NAYYNDKKHOIIOD-UHFFFAOYSA-N 0.000 description 2
- FLVBXVXXXMLMOX-UHFFFAOYSA-N proquinazid Chemical compound C1=C(I)C=C2C(=O)N(CCC)C(OCCC)=NC2=C1 FLVBXVXXXMLMOX-UHFFFAOYSA-N 0.000 description 2
- 235000015136 pumpkin Nutrition 0.000 description 2
- 150000003217 pyrazoles Chemical class 0.000 description 2
- ZLIBICFPKPWGIZ-UHFFFAOYSA-N pyrimethanil Chemical compound CC1=CC(C)=NC(NC=2C=CC=CC=2)=N1 ZLIBICFPKPWGIZ-UHFFFAOYSA-N 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 2
- 229940081974 saccharin Drugs 0.000 description 2
- 235000019204 saccharin Nutrition 0.000 description 2
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- 239000003195 sodium channel blocking agent Substances 0.000 description 2
- 238000009331 sowing Methods 0.000 description 2
- 150000003432 sterols Chemical class 0.000 description 2
- 235000003702 sterols Nutrition 0.000 description 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
- ROZUQUDEWZIBHV-UHFFFAOYSA-N tecloftalam Chemical compound OC(=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1C(=O)NC1=CC=CC(Cl)=C1Cl ROZUQUDEWZIBHV-UHFFFAOYSA-N 0.000 description 2
- XLNZEKHULJKQBA-UHFFFAOYSA-N terbufos Chemical compound CCOP(=S)(OCC)SCSC(C)(C)C XLNZEKHULJKQBA-UHFFFAOYSA-N 0.000 description 2
- 108020002982 thioesterase Proteins 0.000 description 2
- KUAZQDVKQLNFPE-UHFFFAOYSA-N thiram Chemical compound CN(C)C(=S)SSC(=S)N(C)C KUAZQDVKQLNFPE-UHFFFAOYSA-N 0.000 description 2
- 229960002447 thiram Drugs 0.000 description 2
- 230000002110 toxicologic effect Effects 0.000 description 2
- 231100000759 toxicological effect Toxicity 0.000 description 2
- ONCZDRURRATYFI-TVJDWZFNSA-N trifloxystrobin Chemical compound CO\N=C(\C(=O)OC)C1=CC=CC=C1CO\N=C(/C)C1=CC=CC(C(F)(F)F)=C1 ONCZDRURRATYFI-TVJDWZFNSA-N 0.000 description 2
- ZCVAOQKBXKSDMS-AQYZNVCMSA-N (+)-trans-allethrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OC1C(C)=C(CC=C)C(=O)C1 ZCVAOQKBXKSDMS-AQYZNVCMSA-N 0.000 description 1
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 1
- CXBMCYHAMVGWJQ-CABCVRRESA-N (1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)methyl (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OCN1C(=O)C(CCCC2)=C2C1=O CXBMCYHAMVGWJQ-CABCVRRESA-N 0.000 description 1
- YNWVFADWVLCOPU-MDWZMJQESA-N (1E)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol Chemical compound C1=NC=NN1/C(C(O)C(C)(C)C)=C/C1=CC=C(Cl)C=C1 YNWVFADWVLCOPU-MDWZMJQESA-N 0.000 description 1
- KAATUXNTWXVJKI-GGPKGHCWSA-N (1R)-trans-(alphaS)-cypermethrin Chemical compound CC1(C)[C@H](C=C(Cl)Cl)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 KAATUXNTWXVJKI-GGPKGHCWSA-N 0.000 description 1
- FJDPATXIBIBRIM-QFMSAKRMSA-N (1R)-trans-cyphenothrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 FJDPATXIBIBRIM-QFMSAKRMSA-N 0.000 description 1
- SBNFWQZLDJGRLK-RTWAWAEBSA-N (1R)-trans-phenothrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 SBNFWQZLDJGRLK-RTWAWAEBSA-N 0.000 description 1
- ZXQYGBMAQZUVMI-RDDWSQKMSA-N (1S)-cis-(alphaR)-cyhalothrin Chemical compound CC1(C)[C@H](\C=C(/Cl)C(F)(F)F)[C@@H]1C(=O)O[C@@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 ZXQYGBMAQZUVMI-RDDWSQKMSA-N 0.000 description 1
- XERJKGMBORTKEO-VZUCSPMQSA-N (1e)-2-(ethylcarbamoylamino)-n-methoxy-2-oxoethanimidoyl cyanide Chemical compound CCNC(=O)NC(=O)C(\C#N)=N\OC XERJKGMBORTKEO-VZUCSPMQSA-N 0.000 description 1
- AGMMRUPNXPWLGF-AATRIKPKSA-N (2,3,5,6-tetrafluoro-4-methylphenyl)methyl 2,2-dimethyl-3-[(e)-prop-1-enyl]cyclopropane-1-carboxylate Chemical compound CC1(C)C(/C=C/C)C1C(=O)OCC1=C(F)C(F)=C(C)C(F)=C1F AGMMRUPNXPWLGF-AATRIKPKSA-N 0.000 description 1
- NHOWDZOIZKMVAI-UHFFFAOYSA-N (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol Chemical compound C=1N=CN=CC=1C(C=1C(=CC=CC=1)Cl)(O)C1=CC=C(Cl)C=C1 NHOWDZOIZKMVAI-UHFFFAOYSA-N 0.000 description 1
- CXNPLSGKWMLZPZ-GIFSMMMISA-N (2r,3r,6s)-3-[[(3s)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2h-pyran-2-carboxylic acid Chemical compound O1[C@@H](C(O)=O)[C@H](NC(=O)C[C@@H](N)CCN(C)C(N)=N)C=C[C@H]1N1C(=O)N=C(N)C=C1 CXNPLSGKWMLZPZ-GIFSMMMISA-N 0.000 description 1
- LDVVMCZRFWMZSG-OLQVQODUSA-N (3ar,7as)-2-(trichloromethylsulfanyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione Chemical compound C1C=CC[C@H]2C(=O)N(SC(Cl)(Cl)Cl)C(=O)[C@H]21 LDVVMCZRFWMZSG-OLQVQODUSA-N 0.000 description 1
- XUNYDVLIZWUPAW-UHFFFAOYSA-N (4-chlorophenyl) n-(4-methylphenyl)sulfonylcarbamate Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC(=O)OC1=CC=C(Cl)C=C1 XUNYDVLIZWUPAW-UHFFFAOYSA-N 0.000 description 1
- TZURDPUOLIGSAF-VCEOMORVSA-N (4S)-4-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[(2S)-4-amino-2-[[(2S)-2-aminopropanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-methylbutanoyl]amino]-4-oxobutanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-3-carboxy-1-[[(2S,3R)-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid Chemical compound CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N)C(C)C)[C@@H](C)CC)C(C)C)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(O)=O TZURDPUOLIGSAF-VCEOMORVSA-N 0.000 description 1
- WCXDHFDTOYPNIE-RIYZIHGNSA-N (E)-acetamiprid Chemical compound N#C/N=C(\C)N(C)CC1=CC=C(Cl)N=C1 WCXDHFDTOYPNIE-RIYZIHGNSA-N 0.000 description 1
- BKBSMMUEEAWFRX-NBVRZTHBSA-N (E)-flumorph Chemical compound C1=C(OC)C(OC)=CC=C1C(\C=1C=CC(F)=CC=1)=C\C(=O)N1CCOCC1 BKBSMMUEEAWFRX-NBVRZTHBSA-N 0.000 description 1
- CFRPSFYHXJZSBI-DHZHZOJOSA-N (E)-nitenpyram Chemical compound [O-][N+](=O)/C=C(\NC)N(CC)CC1=CC=C(Cl)N=C1 CFRPSFYHXJZSBI-DHZHZOJOSA-N 0.000 description 1
- FZRBKIRIBLNOAM-UHFFFAOYSA-N (E,E)-2-propynyl 3,7,11-trimethyl-2,4-dodecadienoate Chemical compound CC(C)CCCC(C)CC=CC(C)=CC(=O)OCC#C FZRBKIRIBLNOAM-UHFFFAOYSA-N 0.000 description 1
- IQVNEKKDSLOHHK-FNCQTZNRSA-N (E,E)-hydramethylnon Chemical compound N1CC(C)(C)CNC1=NN=C(/C=C/C=1C=CC(=CC=1)C(F)(F)F)\C=C\C1=CC=C(C(F)(F)F)C=C1 IQVNEKKDSLOHHK-FNCQTZNRSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- XGWIJUOSCAQSSV-XHDPSFHLSA-N (S,S)-hexythiazox Chemical compound S([C@H]([C@@H]1C)C=2C=CC(Cl)=CC=2)C(=O)N1C(=O)NC1CCCCC1 XGWIJUOSCAQSSV-XHDPSFHLSA-N 0.000 description 1
- PCKNFPQPGUWFHO-SXBRIOAWSA-N (Z)-flucycloxuron Chemical compound FC1=CC=CC(F)=C1C(=O)NC(=O)NC(C=C1)=CC=C1CO\N=C(C=1C=CC(Cl)=CC=1)\C1CC1 PCKNFPQPGUWFHO-SXBRIOAWSA-N 0.000 description 1
- CKPCAYZTYMHQEX-NBVRZTHBSA-N (e)-1-(2,4-dichlorophenyl)-n-methoxy-2-pyridin-3-ylethanimine Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(=N/OC)/CC1=CC=CN=C1 CKPCAYZTYMHQEX-NBVRZTHBSA-N 0.000 description 1
- XBCKTJDKWPZLJH-ZUPCBTBPSA-N (z,2e)-5-[1-(4-chlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-n,3-dimethylpent-3-enamide Chemical compound N1=C(OC\C=C(\C)/C(=N\OC)/C(=O)NC)C=CN1C1=CC=C(Cl)C=C1 XBCKTJDKWPZLJH-ZUPCBTBPSA-N 0.000 description 1
- IAKOZHOLGAGEJT-UHFFFAOYSA-N 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-Ethane Chemical compound C1=CC(OC)=CC=C1C(C(Cl)(Cl)Cl)C1=CC=C(OC)C=C1 IAKOZHOLGAGEJT-UHFFFAOYSA-N 0.000 description 1
- XQEMNBNCQVQXMO-UHFFFAOYSA-M 1,2-dimethyl-3,5-diphenylpyrazol-1-ium;methyl sulfate Chemical compound COS([O-])(=O)=O.C[N+]=1N(C)C(C=2C=CC=CC=2)=CC=1C1=CC=CC=C1 XQEMNBNCQVQXMO-UHFFFAOYSA-M 0.000 description 1
- MEUXXHGDZUDAAW-UHFFFAOYSA-N 1,3,5-trimethyl-n-(1,1,3-trimethyl-2,3-dihydroinden-4-yl)pyrazole-4-carboxamide Chemical compound C=12C(C)CC(C)(C)C2=CC=CC=1NC(=O)C=1C(C)=NN(C)C=1C MEUXXHGDZUDAAW-UHFFFAOYSA-N 0.000 description 1
- QYPFLRIVEVOAGA-UHFFFAOYSA-N 1,3-dimethyl-n-(1,1,3-trimethyl-2,3-dihydroinden-4-yl)pyrazole-4-carboxamide Chemical compound C=12C(C)CC(C)(C)C2=CC=CC=1NC(=O)C1=CN(C)N=C1C QYPFLRIVEVOAGA-UHFFFAOYSA-N 0.000 description 1
- SBYGUIUIDOUGBU-UHFFFAOYSA-N 1,5-dimethyl-3-(trifluoromethyl)-n-(1,1,3-trimethyl-2,3-dihydroinden-4-yl)pyrazole-4-carboxamide Chemical compound C=12C(C)CC(C)(C)C2=CC=CC=1NC(=O)C1=C(C)N(C)N=C1C(F)(F)F SBYGUIUIDOUGBU-UHFFFAOYSA-N 0.000 description 1
- GXVOAHIRFOAGLK-UHFFFAOYSA-N 1-(4,4-difluorocyclohexyl)-N,5-dimethyl-N-pyridazin-4-ylpyrazole-4-carboxamide Chemical compound FC1(CCC(CC1)N1N=CC(=C1C)C(=O)N(C1=CN=NC=C1)C)F GXVOAHIRFOAGLK-UHFFFAOYSA-N 0.000 description 1
- FMFZDPXBNCGGGI-UHFFFAOYSA-N 1-(4,4-difluorocyclohexyl)-N-ethyl-5-methyl-N-pyridazin-4-ylpyrazole-4-carboxamide Chemical compound FC1(CCC(CC1)N1N=CC(=C1C)C(=O)N(C1=CN=NC=C1)CC)F FMFZDPXBNCGGGI-UHFFFAOYSA-N 0.000 description 1
- WURBVZBTWMNKQT-UHFFFAOYSA-N 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one Chemical compound C1=NC=NN1C(C(=O)C(C)(C)C)OC1=CC=C(Cl)C=C1 WURBVZBTWMNKQT-UHFFFAOYSA-N 0.000 description 1
- RMOGWMIKYWRTKW-UHFFFAOYSA-N 1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol Chemical compound C1=NC=NN1C(C(O)C(C)(C)C)CC1=CC=C(Cl)C=C1 RMOGWMIKYWRTKW-UHFFFAOYSA-N 0.000 description 1
- IAQLCKZJGNTRDO-UHFFFAOYSA-N 1-(4-{4-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2CC(ON=2)C=2C(=CC=CC=2F)F)CC1 IAQLCKZJGNTRDO-UHFFFAOYSA-N 0.000 description 1
- VGPIBGGRCVEHQZ-UHFFFAOYSA-N 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-ol Chemical compound C1=NC=NN1C(C(O)C(C)(C)C)OC(C=C1)=CC=C1C1=CC=CC=C1 VGPIBGGRCVEHQZ-UHFFFAOYSA-N 0.000 description 1
- KEBVBTRIOHKRMU-UHFFFAOYSA-N 1-[(6-chloropyridin-3-yl)methyl]-5-methoxy-7-methyl-8-nitro-3,5,6,7-tetrahydro-2h-imidazo[1,2-a]pyridine Chemical compound C1CN2C(OC)CC(C)C([N+]([O-])=O)=C2N1CC1=CC=C(Cl)N=C1 KEBVBTRIOHKRMU-UHFFFAOYSA-N 0.000 description 1
- SJFPJGQQUXJYPK-UHFFFAOYSA-N 1-[(6-chloropyridin-3-yl)methyl]-7-methyl-8-nitro-3,5,6,7-tetrahydro-2h-imidazo[1,2-a]pyridin-5-ol Chemical compound C12=C([N+]([O-])=O)C(C)CC(O)N2CCN1CC1=CC=C(Cl)N=C1 SJFPJGQQUXJYPK-UHFFFAOYSA-N 0.000 description 1
- MOTGVPXRLDDMSK-UHFFFAOYSA-N 1-[(6-chloropyridin-3-yl)methyl]-7-methyl-8-nitro-5-propoxy-3,5,6,7-tetrahydro-2h-imidazo[1,2-a]pyridine Chemical compound C1CN2C(OCCC)CC(C)C([N+]([O-])=O)=C2N1CC1=CC=C(Cl)N=C1 MOTGVPXRLDDMSK-UHFFFAOYSA-N 0.000 description 1
- CVGWUIISHQTYPZ-UHFFFAOYSA-N 1-[1-(1-cyanocyclopropyl)ethyl]-N,5-dimethyl-N-pyridazin-4-ylpyrazole-4-carboxamide Chemical compound C(#N)C1(CC1)C(C)N1N=CC(=C1C)C(=O)N(C1=CN=NC=C1)C CVGWUIISHQTYPZ-UHFFFAOYSA-N 0.000 description 1
- QUHCCINTOSIBEB-UHFFFAOYSA-N 1-[1-(1-cyanocyclopropyl)ethyl]-n-ethyl-5-methyl-n-pyridazin-4-ylpyrazole-4-carboxamide Chemical compound C=1C=NN=CC=1N(CC)C(=O)C(=C1C)C=NN1C(C)C1(C#N)CC1 QUHCCINTOSIBEB-UHFFFAOYSA-N 0.000 description 1
- HVQHXBNMBZJPLK-UHFFFAOYSA-N 1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-[(2-methylprop-2-en-1-yl)amino]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Chemical compound CC(=C)CNC1=C([S+]([O-])C(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl HVQHXBNMBZJPLK-UHFFFAOYSA-N 0.000 description 1
- LQDARGUHUSPFNL-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]1,2,4-triazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(COC(F)(F)C(F)F)CN1C=NC=N1 LQDARGUHUSPFNL-UHFFFAOYSA-N 0.000 description 1
- PZBPKYOVPCNPJY-UHFFFAOYSA-N 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole Chemical compound ClC1=CC(Cl)=CC=C1C(OCC=C)CN1C=NC=C1 PZBPKYOVPCNPJY-UHFFFAOYSA-N 0.000 description 1
- SSZGPYLZHHCYJC-UHFFFAOYSA-N 1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-fluorophenyl]-4-methyltetrazol-5-one Chemical compound O=C1N(C)N=NN1C1=CC=CC(F)=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 SSZGPYLZHHCYJC-UHFFFAOYSA-N 0.000 description 1
- MGNFYQILYYYUBS-UHFFFAOYSA-N 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine Chemical compound C=1C=C(C(C)(C)C)C=CC=1CC(C)CN1CCCCC1 MGNFYQILYYYUBS-UHFFFAOYSA-N 0.000 description 1
- CCZNNOPONAPVCR-UHFFFAOYSA-N 1-[3-bromo-2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-4-methyltetrazol-5-one Chemical compound O=C1N(C)N=NN1C1=CC=CC(Br)=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 CCZNNOPONAPVCR-UHFFFAOYSA-N 0.000 description 1
- LSKRNXDVFOWBLH-UHFFFAOYSA-N 1-[3-chloro-2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-4-methyltetrazol-5-one Chemical compound O=C1N(C)N=NN1C1=CC=CC(Cl)=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 LSKRNXDVFOWBLH-UHFFFAOYSA-N 0.000 description 1
- NVASWJQSCINQCX-UHFFFAOYSA-N 1-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-cyclopropyl-2-(1,2,4-triazol-1-yl)ethanol Chemical compound C1CC1C(C=1C(=CC(OC=2C=CC(Cl)=CC=2)=CC=1)C(F)(F)F)(O)CN1C=NC=N1 NVASWJQSCINQCX-UHFFFAOYSA-N 0.000 description 1
- FLEFKKUZMDEUIP-QFIPXVFZSA-N 1-[6-[(5s)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4h-1,2-oxazol-3-yl]spiro[1h-2-benzofuran-3,3'-azetidine]-1'-yl]-2-methylsulfonylethanone Chemical compound C1N(C(=O)CS(=O)(=O)C)CC21C1=CC=C(C=3C[C@](ON=3)(C=3C=C(Cl)C(F)=C(Cl)C=3)C(F)(F)F)C=C1CO2 FLEFKKUZMDEUIP-QFIPXVFZSA-N 0.000 description 1
- HILAYQUKKYWPJW-UHFFFAOYSA-N 1-dodecylguanidine Chemical compound CCCCCCCCCCCCN=C(N)N HILAYQUKKYWPJW-UHFFFAOYSA-N 0.000 description 1
- YIKWKLYQRFRGPM-UHFFFAOYSA-N 1-dodecylguanidine acetate Chemical compound CC(O)=O.CCCCCCCCCCCCN=C(N)N YIKWKLYQRFRGPM-UHFFFAOYSA-N 0.000 description 1
- LRCCWFKSGWHDQR-UHFFFAOYSA-N 1-methyl-3-(trifluoromethyl)-n-(1,1,3-trimethyl-2,3-dihydroinden-4-yl)pyrazole-4-carboxamide Chemical compound C=12C(C)CC(C)(C)C2=CC=CC=1NC(=O)C1=CN(C)N=C1C(F)(F)F LRCCWFKSGWHDQR-UHFFFAOYSA-N 0.000 description 1
- JCQPDMJQHYJDSS-UHFFFAOYSA-N 1-methyl-4-[3-methyl-2-[[1-[3-(trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]tetrazol-5-one Chemical compound CN1N=NN(C1=O)C1=C(C(=CC=C1)C)CON=C(C)C1=CC(=CC=C1)C(F)(F)F JCQPDMJQHYJDSS-UHFFFAOYSA-N 0.000 description 1
- VHVCMKPRANXWKQ-UHFFFAOYSA-N 1-methyl-4-[3-methyl-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]methyl]phenyl]tetrazol-5-one Chemical compound CN1N=NN(C1=O)C1=C(C(=CC=C1)C)COC1=C(C=C(C=C1)C1=NN(C=C1)C)C VHVCMKPRANXWKQ-UHFFFAOYSA-N 0.000 description 1
- NFGXHKASABOEEW-UHFFFAOYSA-N 1-methylethyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate Chemical compound COC(C)(C)CCCC(C)CC=CC(C)=CC(=O)OC(C)C NFGXHKASABOEEW-UHFFFAOYSA-N 0.000 description 1
- FMTFEIJHMMQUJI-NJAFHUGGSA-N 102130-98-3 Natural products CC=CCC1=C(C)[C@H](CC1=O)OC(=O)[C@@H]1[C@@H](C=C(C)C)C1(C)C FMTFEIJHMMQUJI-NJAFHUGGSA-N 0.000 description 1
- OXJISOJFVQITNG-UHFFFAOYSA-M 2,4-D choline Chemical compound C[N+](C)(C)CCO.[O-]C(=O)COC1=CC=C(Cl)C=C1Cl OXJISOJFVQITNG-UHFFFAOYSA-M 0.000 description 1
- STMIIPIFODONDC-UHFFFAOYSA-N 2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(O)(CCCC)CN1C=NC=N1 STMIIPIFODONDC-UHFFFAOYSA-N 0.000 description 1
- DNBMPXLFKQCOBV-UHFFFAOYSA-N 2-(2-ethoxyethoxy)ethyl n-(1h-benzimidazol-2-yl)carbamate Chemical compound C1=CC=C2NC(NC(=O)OCCOCCOCC)=NC2=C1 DNBMPXLFKQCOBV-UHFFFAOYSA-N 0.000 description 1
- OMKJEAMIPWDWAL-UHFFFAOYSA-N 2-(3-ethynyl-8-methylquinolin-6-yl)oxy-n-propylbutanamide Chemical compound N1=CC(C#C)=CC2=CC(OC(CC)C(=O)NCCC)=CC(C)=C21 OMKJEAMIPWDWAL-UHFFFAOYSA-N 0.000 description 1
- CMURKFSRGAWINZ-UHFFFAOYSA-N 2-(4-chloro-2,6-dimethylphenyl)-1-hydroxy-9,12-dioxa-4-azadispiro[4.2.4^{8}.2^{5}]tetradec-1-en-3-one Chemical compound CC1=CC(Cl)=CC(C)=C1C(C(N1)=O)=C(O)C11CCC2(OCCO2)CC1 CMURKFSRGAWINZ-UHFFFAOYSA-N 0.000 description 1
- HZJKXKUJVSEEFU-UHFFFAOYSA-N 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Chemical compound C=1C=C(Cl)C=CC=1C(CCCC)(C#N)CN1C=NC=N1 HZJKXKUJVSEEFU-UHFFFAOYSA-N 0.000 description 1
- UFNOUKDBUJZYDE-UHFFFAOYSA-N 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Chemical compound C1=NC=NN1CC(O)(C=1C=CC(Cl)=CC=1)C(C)C1CC1 UFNOUKDBUJZYDE-UHFFFAOYSA-N 0.000 description 1
- KWLVWJPJKJMCSH-UHFFFAOYSA-N 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Chemical compound C1=C(OCC#C)C(OC)=CC(CCNC(=O)C(OCC#C)C=2C=CC(Cl)=CC=2)=C1 KWLVWJPJKJMCSH-UHFFFAOYSA-N 0.000 description 1
- IHASCEQSGGMLRB-UHFFFAOYSA-N 2-(4-chlorophenyl)-n-[4-(3,4-dimethoxyphenyl)-1,2-oxazol-5-yl]-2-prop-2-ynoxyacetamide Chemical compound C1=C(OC)C(OC)=CC=C1C1=C(NC(=O)C(OCC#C)C=2C=CC(Cl)=CC=2)ON=C1 IHASCEQSGGMLRB-UHFFFAOYSA-N 0.000 description 1
- YABFPHSQTSFWQB-UHFFFAOYSA-N 2-(4-fluorophenyl)-1-(1,2,4-triazol-1-yl)-3-(trimethylsilyl)propan-2-ol Chemical compound C=1C=C(F)C=CC=1C(O)(C[Si](C)(C)C)CN1C=NC=N1 YABFPHSQTSFWQB-UHFFFAOYSA-N 0.000 description 1
- NUPJIGQFXCQJBK-UHFFFAOYSA-N 2-(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)-5-(methoxymethyl)nicotinic acid Chemical compound OC(=O)C1=CC(COC)=CN=C1C1=NC(C)(C(C)C)C(=O)N1 NUPJIGQFXCQJBK-UHFFFAOYSA-N 0.000 description 1
- NGLCOYIAJMJYQI-UHFFFAOYSA-N 2-(4-methoxyiminocyclohexyl)-2-(3,3,3-trifluoropropylsulfonyl)acetonitrile Chemical compound CON=C1CCC(C(C#N)S(=O)(=O)CCC(F)(F)F)CC1 NGLCOYIAJMJYQI-UHFFFAOYSA-N 0.000 description 1
- LMBOBAWFGUTZRU-UHFFFAOYSA-N 2-(5-fluoropyridin-3-yl)-5-(6-pyrimidin-2-ylpyridin-2-yl)-1,3-thiazole Chemical compound FC1=CN=CC(C=2SC(=CN=2)C=2N=C(C=CC=2)C=2N=CC=CN=2)=C1 LMBOBAWFGUTZRU-UHFFFAOYSA-N 0.000 description 1
- AGVACZYQCJRDQE-UHFFFAOYSA-N 2-(6-benzylpyridin-2-yl)quinazoline Chemical compound C=1C=CC(C=2N=C3C=CC=CC3=CN=2)=NC=1CC1=CC=CC=C1 AGVACZYQCJRDQE-UHFFFAOYSA-N 0.000 description 1
- QKJJCZYFXJCKRX-HZHKWBLPSA-N 2-[(2s,3s,6r)-6-[4-amino-5-(hydroxymethyl)-2-oxopyrimidin-1-yl]-3-[[(2s)-2-amino-3-hydroxypropanoyl]amino]-3,6-dihydro-2h-pyran-2-yl]-5-(diaminomethylideneamino)-2,4-dihydroxypentanoic acid Chemical compound O1[C@H](C(O)(CC(O)CN=C(N)N)C(O)=O)[C@@H](NC(=O)[C@H](CO)N)C=C[C@@H]1N1C(=O)N=C(N)C(CO)=C1 QKJJCZYFXJCKRX-HZHKWBLPSA-N 0.000 description 1
- ZEXXEODAXHSRDJ-UHFFFAOYSA-N 2-[(ethanesulfonyl)amino]-5-fluoro-4-[4-methyl-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-1,2,4-triazol-1-yl]benzene-1-carbothioamide Chemical compound CS(=O)(=O)OC1=CC=CC(Cl)=C1C1ON=C(C=2N=C(SC=2)C2CCN(CC2)C(=O)CN2C(=CC(=N2)C(F)F)C(F)F)C1 ZEXXEODAXHSRDJ-UHFFFAOYSA-N 0.000 description 1
- GSSLIXUCWSWMKG-UHFFFAOYSA-N 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)butan-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(Cl)C=1C(O)(CC)CN1C=NC=N1 GSSLIXUCWSWMKG-UHFFFAOYSA-N 0.000 description 1
- HJGORPAOVKAUBJ-UHFFFAOYSA-N 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)pent-3-yn-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(Cl)C=1C(O)(C#CC)CN1C=NC=N1 HJGORPAOVKAUBJ-UHFFFAOYSA-N 0.000 description 1
- LTJVSKGTIJFYRK-UHFFFAOYSA-N 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)pentan-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(Cl)C=1C(O)(CCC)CN1C=NC=N1 LTJVSKGTIJFYRK-UHFFFAOYSA-N 0.000 description 1
- SJRRBGICVBPXCH-UHFFFAOYSA-N 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-3-methyl-1-(1,2,4-triazol-1-yl)butan-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(Cl)C=1C(O)(C(C)C)CN1C=NC=N1 SJRRBGICVBPXCH-UHFFFAOYSA-N 0.000 description 1
- RUUBFCPAVMVRMA-UHFFFAOYSA-N 2-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-(trifluoromethyl)-1,2,4-triazol-3-amine Chemical compound C1=C(S(=O)CC(F)(F)F)C(C)=CC(F)=C1N1C(N)=NC(C(F)(F)F)=N1 RUUBFCPAVMVRMA-UHFFFAOYSA-N 0.000 description 1
- BOTNFCTYKJBUMU-UHFFFAOYSA-N 2-[4-(2-methylpropyl)piperazin-4-ium-1-yl]-2-oxoacetate Chemical compound CC(C)C[NH+]1CCN(C(=O)C([O-])=O)CC1 BOTNFCTYKJBUMU-UHFFFAOYSA-N 0.000 description 1
- HSUIUGJIZSLSPE-UHFFFAOYSA-N 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)butan-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(C(F)(F)F)C=1C(O)(CC)CN1C=NC=N1 HSUIUGJIZSLSPE-UHFFFAOYSA-N 0.000 description 1
- MQRIRFCJJWIQDT-UHFFFAOYSA-N 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)pentan-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(C(F)(F)F)C=1C(O)(CCC)CN1C=NC=N1 MQRIRFCJJWIQDT-UHFFFAOYSA-N 0.000 description 1
- JERZEQUMJNCPRJ-UHFFFAOYSA-N 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(C(F)(F)F)C=1C(O)(C)CN1C=NC=N1 JERZEQUMJNCPRJ-UHFFFAOYSA-N 0.000 description 1
- SIIJJFOXEOHODQ-UHFFFAOYSA-N 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-3-methyl-1-(1,2,4-triazol-1-yl)butan-2-ol Chemical compound C=1C=C(OC=2C=CC(Cl)=CC=2)C=C(C(F)(F)F)C=1C(O)(C(C)C)CN1C=NC=N1 SIIJJFOXEOHODQ-UHFFFAOYSA-N 0.000 description 1
- NMAYBFXZJYUNQZ-UHFFFAOYSA-N 2-[4-(4-fluorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol Chemical compound C=1C=C(OC=2C=CC(F)=CC=2)C=C(C(F)(F)F)C=1C(O)(C)CN1C=NC=N1 NMAYBFXZJYUNQZ-UHFFFAOYSA-N 0.000 description 1
- YANWOMFJWXJQEF-UHFFFAOYSA-N 2-[6-(3-fluoro-4-methoxyphenyl)-5-methylpyridin-2-yl]quinazoline Chemical compound C1=C(F)C(OC)=CC=C1C1=NC(C=2N=C3C=CC=CC3=CN=2)=CC=C1C YANWOMFJWXJQEF-UHFFFAOYSA-N 0.000 description 1
- XAYMVFWOJIOUTA-UHFFFAOYSA-N 2-[8-[8-(diaminomethylideneamino)octylamino]octyl]guanidine;2-dodecylbenzenesulfonic acid Chemical compound CCCCCCCCCCCCC1=CC=CC=C1S(O)(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S(O)(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S(O)(=O)=O.NC(N)=NCCCCCCCCNCCCCCCCCN=C(N)N XAYMVFWOJIOUTA-UHFFFAOYSA-N 0.000 description 1
- PVTHJAPFENJVNC-UHFFFAOYSA-N 2-amino-2-[5-amino-2-methyl-6-(2,3,4,5,6-pentahydroxycyclohexyl)oxyoxan-3-yl]iminoacetic acid Chemical compound NC1CC(N=C(N)C(O)=O)C(C)OC1OC1C(O)C(O)C(O)C(O)C1O PVTHJAPFENJVNC-UHFFFAOYSA-N 0.000 description 1
- OWDLFBLNMPCXSD-UHFFFAOYSA-N 2-chloro-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide Chemical compound CC1=CC=CC(C)=C1N(C(=O)CCl)C1C(=O)OCC1 OWDLFBLNMPCXSD-UHFFFAOYSA-N 0.000 description 1
- QAYYATIAHWLJIF-UHFFFAOYSA-N 2-chloro-n-[3-[[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-iodo-6-(trifluoromethyl)phenyl]carbamoyl]phenyl]pyridine-3-carboxamide Chemical compound FC(F)(F)C1=CC(C(F)(C(F)(F)F)C(F)(F)F)=CC(I)=C1NC(=O)C1=CC=CC(NC(=O)C=2C(=NC=CC=2)Cl)=C1 QAYYATIAHWLJIF-UHFFFAOYSA-N 0.000 description 1
- MHQDKLPRHCFNQI-UHFFFAOYSA-N 2-fluoro-N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-iodo-6-(trifluoromethyl)phenyl]-3-(phenacylamino)benzamide Chemical compound Fc1c(NCC(=O)c2ccccc2)cccc1C(=O)Nc1c(I)cc(cc1C(F)(F)F)C(F)(C(F)(F)F)C(F)(F)F MHQDKLPRHCFNQI-UHFFFAOYSA-N 0.000 description 1
- 229940044120 2-n-octyl-4-isothiazolin-3-one Drugs 0.000 description 1
- AVGVFDSUDIUXEU-UHFFFAOYSA-N 2-octyl-1,2-thiazolidin-3-one Chemical compound CCCCCCCCN1SCCC1=O AVGVFDSUDIUXEU-UHFFFAOYSA-N 0.000 description 1
- KRYQDBFHAFVBSW-UHFFFAOYSA-N 2-pyridin-3-yl-5-(6-pyrimidin-2-ylpyridin-2-yl)-1,3-thiazole Chemical compound C=1N=C(C=2C=NC=CC=2)SC=1C(N=1)=CC=CC=1C1=NC=CC=N1 KRYQDBFHAFVBSW-UHFFFAOYSA-N 0.000 description 1
- ZRDUSMYWDRPZRM-UHFFFAOYSA-N 2-sec-butyl-4,6-dinitrophenyl 3-methylbut-2-enoate Chemical compound CCC(C)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1OC(=O)C=C(C)C ZRDUSMYWDRPZRM-UHFFFAOYSA-N 0.000 description 1
- PDPWCKVFIFAQIQ-UHFFFAOYSA-N 2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide Chemical compound CNC(=O)C(OC)C1=CC=CC=C1COC1=CC(C)=CC=C1C PDPWCKVFIFAQIQ-UHFFFAOYSA-N 0.000 description 1
- AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 description 1
- AUQAUAIUNJIIEP-UHFFFAOYSA-N 3,4,5-trimethylphenyl methylcarbamate Chemical compound CNC(=O)OC1=CC(C)=C(C)C(C)=C1 AUQAUAIUNJIIEP-UHFFFAOYSA-N 0.000 description 1
- SOUGWDPPRBKJEX-UHFFFAOYSA-N 3,5-dichloro-N-(1-chloro-3-methyl-2-oxopentan-3-yl)-4-methylbenzamide Chemical compound ClCC(=O)C(C)(CC)NC(=O)C1=CC(Cl)=C(C)C(Cl)=C1 SOUGWDPPRBKJEX-UHFFFAOYSA-N 0.000 description 1
- SWBHWUYHHJCADA-UHFFFAOYSA-N 3-(2-chlorophenyl)-6-(2,6-difluorophenyl)-1,2,4,5-tetrazine Chemical compound FC1=CC=CC(F)=C1C1=NN=C(C=2C(=CC=CC=2)Cl)N=N1 SWBHWUYHHJCADA-UHFFFAOYSA-N 0.000 description 1
- BZGLBXYQOMFXAU-UHFFFAOYSA-N 3-(2-methylpiperidin-1-yl)propyl 3,4-dichlorobenzoate Chemical compound CC1CCCCN1CCCOC(=O)C1=CC=C(Cl)C(Cl)=C1 BZGLBXYQOMFXAU-UHFFFAOYSA-N 0.000 description 1
- FSCWZHGZWWDELK-UHFFFAOYSA-N 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione Chemical compound O=C1C(C)(C=C)OC(=O)N1C1=CC(Cl)=CC(Cl)=C1 FSCWZHGZWWDELK-UHFFFAOYSA-N 0.000 description 1
- KNUJXXAPWWVVAG-UHFFFAOYSA-N 3-(difluoromethyl)-1,5-dimethyl-n-(1,1,3-trimethyl-2,3-dihydroinden-4-yl)pyrazole-4-carboxamide Chemical compound C=12C(C)CC(C)(C)C2=CC=CC=1NC(=O)C1=C(C)N(C)N=C1C(F)F KNUJXXAPWWVVAG-UHFFFAOYSA-N 0.000 description 1
- YTCIYOXHHQLDEI-UHFFFAOYSA-N 3-(difluoromethyl)-1-methyl-n-(1,1,3-trimethyl-2,3-dihydroinden-4-yl)pyrazole-4-carboxamide Chemical compound C=12C(C)CC(C)(C)C2=CC=CC=1NC(=O)C1=CN(C)N=C1C(F)F YTCIYOXHHQLDEI-UHFFFAOYSA-N 0.000 description 1
- XCGBHLLWJZOLEM-UHFFFAOYSA-N 3-(difluoromethyl)-N-(7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1-methyl-1H-pyrazole-4-carboxamide Chemical compound CC1CC(C)(C)C(C(=CC=2)F)=C1C=2NC(=O)C1=CN(C)N=C1C(F)F XCGBHLLWJZOLEM-UHFFFAOYSA-N 0.000 description 1
- CUTZZBQQGUIEGT-UHFFFAOYSA-N 3-[(3,4-dichloro-1,2-thiazol-5-yl)methoxy]-1,2-benzothiazole 1,1-dioxide Chemical compound ClC1=NSC(COC=2C3=CC=CC=C3S(=O)(=O)N=2)=C1Cl CUTZZBQQGUIEGT-UHFFFAOYSA-N 0.000 description 1
- UKPDFCZYKKAJTK-UHFFFAOYSA-N 3-[3-(4-fluorophenyl)-2,6-dimethylphenyl]-4-hydroxy-8-oxa-1-azaspiro[4.5]dec-3-en-2-one Chemical compound CC1=CC=C(C=2C=CC(F)=CC=2)C(C)=C1C(C(N1)=O)=C(O)C21CCOCC2 UKPDFCZYKKAJTK-UHFFFAOYSA-N 0.000 description 1
- DHTJFQWHCVTNRY-UHFFFAOYSA-N 3-[5-(4-chlorophenyl)-2,3-dimethyl-1,2-oxazolidin-3-yl]pyridine Chemical compound CN1OC(C=2C=CC(Cl)=CC=2)CC1(C)C1=CC=CN=C1 DHTJFQWHCVTNRY-UHFFFAOYSA-N 0.000 description 1
- SEADPLLEYCNNGA-UHFFFAOYSA-N 3-[benzoyl(methyl)amino]-n-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-iodo-6-(trifluoromethyl)phenyl]benzamide Chemical compound C=1C=CC(C(=O)NC=2C(=CC(=CC=2I)C(F)(C(F)(F)F)C(F)(F)F)C(F)(F)F)=CC=1N(C)C(=O)C1=CC=CC=C1 SEADPLLEYCNNGA-UHFFFAOYSA-N 0.000 description 1
- QZMQZUFFUNIGOE-LBPRGKRZSA-N 3-chloro-1-n-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-2-n-[(2s)-1-methylsulfonylpropan-2-yl]benzene-1,2-dicarboxamide Chemical compound CS(=O)(=O)C[C@H](C)NC(=O)C1=C(Cl)C=CC=C1C(=O)NC1=CC=C(C(F)(C(F)(F)F)C(F)(F)F)C=C1C QZMQZUFFUNIGOE-LBPRGKRZSA-N 0.000 description 1
- ZNBJSAAROMDHOX-UHFFFAOYSA-N 3-chloro-4-(2,6-difluorophenyl)-6-methyl-5-phenylpyridazine Chemical compound C=1C=CC=CC=1C=1C(C)=NN=C(Cl)C=1C1=C(F)C=CC=C1F ZNBJSAAROMDHOX-UHFFFAOYSA-N 0.000 description 1
- OMSQGGMSQNHEMG-UHFFFAOYSA-N 3-chloro-6-methyl-5-phenyl-4-(2,4,6-trifluorophenyl)pyridazine Chemical compound CC1=NN=C(Cl)C(C=2C(=CC(F)=CC=2F)F)=C1C1=CC=CC=C1 OMSQGGMSQNHEMG-UHFFFAOYSA-N 0.000 description 1
- HDKWFBCPLKNOCK-SFHVURJKSA-N 3-methyl-n-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-5-[(5s)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4h-1,2-oxazol-3-yl]thiophene-2-carboxamide Chemical compound S1C(C(=O)NCC(=O)NCC(F)(F)F)=C(C)C=C1C1=NO[C@](C(F)(F)F)(C=2C=C(Cl)C(Cl)=C(Cl)C=2)C1 HDKWFBCPLKNOCK-SFHVURJKSA-N 0.000 description 1
- IOPXHRCFWXPUIB-UHFFFAOYSA-N 3-pyridin-2-yl-1h-indazole Chemical class N1=CC=CC=C1C1=NNC2=CC=CC=C12 IOPXHRCFWXPUIB-UHFFFAOYSA-N 0.000 description 1
- HSRXLAJZZXXCNQ-UHFFFAOYSA-N 4,4,5-trifluoro-3,3-dimethyl-1-quinolin-3-ylisoquinoline Chemical compound C12=CC=CC(F)=C2C(F)(F)C(C)(C)N=C1C1=CN=C(C=CC=C2)C2=C1 HSRXLAJZZXXCNQ-UHFFFAOYSA-N 0.000 description 1
- SWTPIYGGSMJRTB-UHFFFAOYSA-N 4,4-difluoro-3,3-dimethyl-1-quinolin-3-ylisoquinoline Chemical compound C12=CC=CC=C2C(F)(F)C(C)(C)N=C1C1=CN=C(C=CC=C2)C2=C1 SWTPIYGGSMJRTB-UHFFFAOYSA-N 0.000 description 1
- ZXVONLUNISGICL-UHFFFAOYSA-N 4,6-dinitro-o-cresol Chemical compound CC1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1O ZXVONLUNISGICL-UHFFFAOYSA-N 0.000 description 1
- HTXMJCHSFOPGME-UHFFFAOYSA-N 4,7-dimethoxy-1,3-benzodioxole Chemical compound COC1=CC=C(OC)C2=C1OCO2 HTXMJCHSFOPGME-UHFFFAOYSA-N 0.000 description 1
- LBGMYUQCXJJLIR-UHFFFAOYSA-N 4-(2-bromo-4-fluorophenyl)-n-(2-chloro-6-fluorophenyl)-2,5-dimethylpyrazol-3-amine Chemical compound C=1C=C(F)C=C(Br)C=1C=1C(C)=NN(C)C=1NC1=C(F)C=CC=C1Cl LBGMYUQCXJJLIR-UHFFFAOYSA-N 0.000 description 1
- RQDJADAKIFFEKQ-UHFFFAOYSA-N 4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile Chemical compound C1=CC(Cl)=CC=C1CCC(C=1C=CC=CC=1)(C#N)CN1N=CN=C1 RQDJADAKIFFEKQ-UHFFFAOYSA-N 0.000 description 1
- CUSXUSVGOOSADT-UHFFFAOYSA-N 4-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide Chemical compound FC(C1=NN(C(=C1)C(F)F)CC(=O)N1CCC(CC1)C1=CC(=NC=C1)C(=O)NC1CCCC2=CC=CC=C12)F CUSXUSVGOOSADT-UHFFFAOYSA-N 0.000 description 1
- PNICFNRAKHFRHN-UHFFFAOYSA-N 4-[1-[2-[3,5-bis(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide Chemical compound FC(C1=NN(C(=C1)C(F)(F)F)CC(=O)N1CCC(CC1)C1=CC(=NC=C1)C(=O)NC1CCCC2=CC=CC=C12)(F)F PNICFNRAKHFRHN-UHFFFAOYSA-N 0.000 description 1
- NSLNLNXAEPBGRV-UHFFFAOYSA-N 4-[1-[2-[3-(difluoromethyl)-5-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide Chemical compound FC(C1=NN(C(=C1)C(F)(F)F)CC(=O)N1CCC(CC1)C1=CC(=NC=C1)C(=O)NC1CCCC2=CC=CC=C12)F NSLNLNXAEPBGRV-UHFFFAOYSA-N 0.000 description 1
- OEZNWKGNYIKMOI-UHFFFAOYSA-N 4-[1-[2-[3-(difluoromethyl)-5-methylpyrazol-1-yl]acetyl]piperidin-4-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide Chemical compound FC(C1=NN(C(=C1)C)CC(=O)N1CCC(CC1)C1=CC(=NC=C1)C(=O)NC1CCCC2=CC=CC=C12)F OEZNWKGNYIKMOI-UHFFFAOYSA-N 0.000 description 1
- SUDKTHLYEGJVKF-UHFFFAOYSA-N 4-[1-[2-[5-(difluoromethyl)-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide Chemical compound FC(C1=CC(=NN1CC(=O)N1CCC(CC1)C1=CC(=NC=C1)C(=O)NC1CCCC2=CC=CC=C12)C(F)(F)F)F SUDKTHLYEGJVKF-UHFFFAOYSA-N 0.000 description 1
- MLUYQAXGWMNECN-UHFFFAOYSA-N 4-[1-[2-[5-cyclopropyl-3-(difluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide Chemical compound C1(CC1)C1=CC(=NN1CC(=O)N1CCC(CC1)C1=CC(=NC=C1)C(=O)NC1CCCC2=CC=CC=C12)C(F)F MLUYQAXGWMNECN-UHFFFAOYSA-N 0.000 description 1
- SYTNGALGRYRILA-UHFFFAOYSA-N 4-[1-[2-[5-cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide Chemical compound C1(CC1)C1=CC(=NN1CC(=O)N1CCC(CC1)C1=CC(=NC=C1)C(=O)NC1CCCC2=CC=CC=C12)C(F)(F)F SYTNGALGRYRILA-UHFFFAOYSA-N 0.000 description 1
- GGCKILCJTFONPS-UHFFFAOYSA-N 4-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]piperidin-4-yl]-n-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2C=C(N=CC=2)C(=O)NC2C3=CC=CC=C3CCC2)CC1 GGCKILCJTFONPS-UHFFFAOYSA-N 0.000 description 1
- BPFUIWLQXNPZHI-UHFFFAOYSA-N 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-[(methoxyamino)methylidene]-2-methylbenzamide Chemical compound C1=C(C)C(C(=O)N\C=N/OC)=CC=C1C1=NOC(C(F)(F)F)(C=2C=C(Cl)C=C(Cl)C=2)C1 BPFUIWLQXNPZHI-UHFFFAOYSA-N 0.000 description 1
- ATCHXZDKOPPPST-UHFFFAOYSA-N 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4h-1,2-oxazol-3-yl]-2-methyl-n-(1-oxothietan-3-yl)benzamide Chemical compound CC1=CC(C=2CC(ON=2)(C=2C=C(Cl)C=C(Cl)C=2)C(F)(F)F)=CC=C1C(=O)NC1CS(=O)C1 ATCHXZDKOPPPST-UHFFFAOYSA-N 0.000 description 1
- OXDDDHGGRFRLEE-UHFFFAOYSA-N 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4h-1,2-oxazol-3-yl]-n-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide Chemical compound C12=CC=CC=C2C(C(=O)NCC(=O)NCC(F)(F)F)=CC=C1C(C1)=NOC1(C(F)(F)F)C1=CC(Cl)=CC(C(F)(F)F)=C1 OXDDDHGGRFRLEE-UHFFFAOYSA-N 0.000 description 1
- VFYIDGHLULLRBH-UHFFFAOYSA-N 4-cyano-3-[(4-cyano-2-methylbenzoyl)amino]-n-[2,6-dichloro-4-(1,1,1,2,3,3,4,4,4-nonafluorobutan-2-yl)phenyl]-2-fluorobenzamide Chemical compound CC1=CC(C#N)=CC=C1C(=O)NC1=C(F)C(C(=O)NC=2C(=CC(=CC=2Cl)C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)Cl)=CC=C1C#N VFYIDGHLULLRBH-UHFFFAOYSA-N 0.000 description 1
- CSJFAXFICOCFLH-UHFFFAOYSA-N 4-cyano-n-[2-cyano-5-[[2,6-dibromo-4-(1,1,1,2,3,3,4,4,4-nonafluorobutan-2-yl)phenyl]carbamoyl]phenyl]-2-methylbenzamide Chemical compound CC1=CC(C#N)=CC=C1C(=O)NC1=CC(C(=O)NC=2C(=CC(=CC=2Br)C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)Br)=CC=C1C#N CSJFAXFICOCFLH-UHFFFAOYSA-N 0.000 description 1
- REQCFOSCPFWLHT-UHFFFAOYSA-N 4-cyano-n-[2-cyano-5-[[2,6-dichloro-4-(1,1,1,2,3,3,4,4,4-nonafluorobutan-2-yl)phenyl]carbamoyl]phenyl]-2-methylbenzamide Chemical compound CC1=CC(C#N)=CC=C1C(=O)NC1=CC(C(=O)NC=2C(=CC(=CC=2Cl)C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)Cl)=CC=C1C#N REQCFOSCPFWLHT-UHFFFAOYSA-N 0.000 description 1
- PGYDGBCATBINCB-UHFFFAOYSA-N 4-diethoxyphosphoryl-n,n-dimethylaniline Chemical compound CCOP(=O)(OCC)C1=CC=C(N(C)C)C=C1 PGYDGBCATBINCB-UHFFFAOYSA-N 0.000 description 1
- SBUKOHLFHYSZNG-UHFFFAOYSA-N 4-dodecyl-2,6-dimethylmorpholine Chemical compound CCCCCCCCCCCCN1CC(C)OC(C)C1 SBUKOHLFHYSZNG-UHFFFAOYSA-N 0.000 description 1
- HQJIHVZTLDUUBP-UHFFFAOYSA-N 5-[6-(1,3-dioxan-2-yl)pyridin-2-yl]-2-pyridin-3-yl-1,3-thiazole Chemical compound O1CCCOC1C1=CC=CC(C=2SC(=NC=2)C=2C=NC=CC=2)=N1 HQJIHVZTLDUUBP-UHFFFAOYSA-N 0.000 description 1
- XJFIKRXIJXAJGH-UHFFFAOYSA-N 5-chloro-1,3-dihydroimidazo[4,5-b]pyridin-2-one Chemical group ClC1=CC=C2NC(=O)NC2=N1 XJFIKRXIJXAJGH-UHFFFAOYSA-N 0.000 description 1
- ZGBKIRCRHOIXAN-UHFFFAOYSA-N 5-chloro-1-(4,6-dimethoxypyrimidin-2-yl)-2-methylbenzimidazole Chemical compound COC1=CC(OC)=NC(N2C3=CC=C(Cl)C=C3N=C2C)=N1 ZGBKIRCRHOIXAN-UHFFFAOYSA-N 0.000 description 1
- NEKULYKCZPJMMJ-UHFFFAOYSA-N 5-chloro-N-{1-[4-(difluoromethoxy)phenyl]propyl}-6-methylpyrimidin-4-amine Chemical compound C=1C=C(OC(F)F)C=CC=1C(CC)NC1=NC=NC(C)=C1Cl NEKULYKCZPJMMJ-UHFFFAOYSA-N 0.000 description 1
- ZALZMUXMSIVXKA-UHFFFAOYSA-N 5-fluoro-2-[(4-fluorophenyl)methoxy]pyrimidin-4-amine Chemical compound C1=C(F)C(N)=NC(OCC=2C=CC(F)=CC=2)=N1 ZALZMUXMSIVXKA-UHFFFAOYSA-N 0.000 description 1
- CGRCPZUQMBYVPZ-UHFFFAOYSA-N 5-fluoro-2-[(4-methylphenyl)methoxy]pyrimidin-4-amine Chemical compound C1=CC(C)=CC=C1COC1=NC=C(F)C(N)=N1 CGRCPZUQMBYVPZ-UHFFFAOYSA-N 0.000 description 1
- GNUDLKJUYSXMNO-UHFFFAOYSA-N 5-fluoro-3,3,4,4-tetramethyl-1-quinolin-3-ylisoquinoline Chemical compound C12=CC=CC(F)=C2C(C)(C)C(C)(C)N=C1C1=CN=C(C=CC=C2)C2=C1 GNUDLKJUYSXMNO-UHFFFAOYSA-N 0.000 description 1
- 108010011619 6-Phytase Proteins 0.000 description 1
- SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 description 1
- JVGXNGXFTFLIGB-UHFFFAOYSA-N 9-fluoro-2,2-dimethyl-5-quinolin-3-yl-3h-1,4-benzoxazepine Chemical compound C12=CC=CC(F)=C2OC(C)(C)CN=C1C1=CN=C(C=CC=C2)C2=C1 JVGXNGXFTFLIGB-UHFFFAOYSA-N 0.000 description 1
- 241000916767 Acalymma vittatum Species 0.000 description 1
- 241001143309 Acanthoscelides obtectus Species 0.000 description 1
- 241000238876 Acari Species 0.000 description 1
- 241000132121 Acaridae Species 0.000 description 1
- 241000934064 Acarus siro Species 0.000 description 1
- 239000005651 Acequinocyl Substances 0.000 description 1
- 241001558864 Aceria Species 0.000 description 1
- 241000627745 Aceria anthocoptes Species 0.000 description 1
- 239000005875 Acetamiprid Substances 0.000 description 1
- 241000238818 Acheta domesticus Species 0.000 description 1
- 241001351288 Achroia grisella Species 0.000 description 1
- 239000005964 Acibenzolar-S-methyl Substances 0.000 description 1
- 241000526180 Acizzia Species 0.000 description 1
- 241001204086 Acleris Species 0.000 description 1
- 241000599456 Acleris fimbriana Species 0.000 description 1
- 241000495828 Acleris gloverana Species 0.000 description 1
- 241000834107 Acleris variana Species 0.000 description 1
- 239000005652 Acrinathrin Substances 0.000 description 1
- 241000580753 Acrolepiopsis assectella Species 0.000 description 1
- 241000819811 Acronicta major Species 0.000 description 1
- 241001014340 Acrosternum Species 0.000 description 1
- 241001506009 Aculops Species 0.000 description 1
- 241000079319 Aculops lycopersici Species 0.000 description 1
- 241001159389 Aculops pelekassi Species 0.000 description 1
- 241001506414 Aculus Species 0.000 description 1
- 241000253994 Acyrthosiphon pisum Species 0.000 description 1
- 241000917225 Adelges laricis Species 0.000 description 1
- 241001107053 Adelges tsugae Species 0.000 description 1
- 241000663326 Adelphocoris Species 0.000 description 1
- 241000693815 Adelphocoris rapidus Species 0.000 description 1
- 241001227264 Adoretus Species 0.000 description 1
- 241001672675 Adoxophyes Species 0.000 description 1
- 241000256111 Aedes <genus> Species 0.000 description 1
- 241000256118 Aedes aegypti Species 0.000 description 1
- 241000256173 Aedes albopictus Species 0.000 description 1
- 241000484420 Aedia leucomelas Species 0.000 description 1
- 241001164222 Aeneolamia Species 0.000 description 1
- 241000902874 Agelastica alni Species 0.000 description 1
- 241000902467 Agonoscena Species 0.000 description 1
- 241001470783 Agrilus Species 0.000 description 1
- 241000275062 Agrilus planipennis Species 0.000 description 1
- 241001470785 Agrilus sinuatus Species 0.000 description 1
- 241001136265 Agriotes Species 0.000 description 1
- 241000600972 Agriotes fuscicollis Species 0.000 description 1
- 241001136249 Agriotes lineatus Species 0.000 description 1
- 241000218473 Agrotis Species 0.000 description 1
- 241001586735 Agrotis exclamationis Species 0.000 description 1
- 241000566547 Agrotis ipsilon Species 0.000 description 1
- 241000449794 Alabama argillacea Species 0.000 description 1
- 241000308252 Aleurocanthus woglumi Species 0.000 description 1
- 241001414848 Aleurodicus Species 0.000 description 1
- 241000108084 Aleurodicus dispersus Species 0.000 description 1
- 241000549142 Aleurodicus floccissimus Species 0.000 description 1
- 241001155864 Aleurolobus barodensis Species 0.000 description 1
- 241001136547 Aleurothrixus Species 0.000 description 1
- 241001124203 Alphitobius diaperinus Species 0.000 description 1
- 241001149961 Alternaria brassicae Species 0.000 description 1
- 241000860757 Alternaria grossulariae Species 0.000 description 1
- 239000005952 Aluminium phosphide Substances 0.000 description 1
- 241000238679 Amblyomma Species 0.000 description 1
- 241000238682 Amblyomma americanum Species 0.000 description 1
- 241001480737 Amblyomma maculatum Species 0.000 description 1
- 241001480834 Amblyomma variegatum Species 0.000 description 1
- 239000005726 Ametoctradin Substances 0.000 description 1
- 239000005727 Amisulbrom Substances 0.000 description 1
- 241000673723 Ampelophaga Species 0.000 description 1
- 241000673721 Ampelophaga rubiginosa Species 0.000 description 1
- 241001354436 Amphipoea fucosa Species 0.000 description 1
- 241000839189 Amrasca Species 0.000 description 1
- 241001259789 Amyelois transitella Species 0.000 description 1
- 244000144725 Amygdalus communis Species 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 241000310247 Amyna axis Species 0.000 description 1
- 241001368096 Anacampsis Species 0.000 description 1
- 241001198505 Anarsia lineatella Species 0.000 description 1
- 241000663922 Anasa tristis Species 0.000 description 1
- 241001136525 Anastrepha ludens Species 0.000 description 1
- 241001147657 Ancylostoma Species 0.000 description 1
- 241000520197 Ancylostoma ceylanicum Species 0.000 description 1
- 241000498253 Ancylostoma duodenale Species 0.000 description 1
- 241000380490 Anguina Species 0.000 description 1
- 241000380499 Anguina funesta Species 0.000 description 1
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical class NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 1
- 241001256085 Anisandrus dispar Species 0.000 description 1
- 244000005213 Anisoptera costata Species 0.000 description 1
- 241000153204 Anisota senatoria Species 0.000 description 1
- 241000411449 Anobium punctatum Species 0.000 description 1
- 241000241395 Anomala corpulenta Species 0.000 description 1
- 241000519878 Anomala rufocuprea Species 0.000 description 1
- 241000256186 Anopheles <genus> Species 0.000 description 1
- 241000256187 Anopheles albimanus Species 0.000 description 1
- 241000060075 Anopheles crucians Species 0.000 description 1
- 241000256199 Anopheles freeborni Species 0.000 description 1
- 241000256182 Anopheles gambiae Species 0.000 description 1
- 241000680856 Anopheles leucosphyrus Species 0.000 description 1
- 241000132163 Anopheles maculipennis Species 0.000 description 1
- 241000256190 Anopheles quadrimaculatus Species 0.000 description 1
- 241000027431 Anoplophora Species 0.000 description 1
- 241001609695 Anoplophora glabripennis Species 0.000 description 1
- 241000693245 Antestiopsis Species 0.000 description 1
- 241000255974 Antheraea Species 0.000 description 1
- 241000254177 Anthonomus Species 0.000 description 1
- 241001156002 Anthonomus pomorum Species 0.000 description 1
- 241001640910 Anthrenus Species 0.000 description 1
- 241000797665 Anuraphis subterranea Species 0.000 description 1
- 241001414827 Aonidiella Species 0.000 description 1
- 241000368734 Apamea Species 0.000 description 1
- 241000294569 Aphelenchoides Species 0.000 description 1
- 241000134843 Aphelenchoides besseyi Species 0.000 description 1
- 241001600407 Aphis <genus> Species 0.000 description 1
- 241001151957 Aphis aurantii Species 0.000 description 1
- 241000952611 Aphis craccivora Species 0.000 description 1
- 241001425390 Aphis fabae Species 0.000 description 1
- 241000566651 Aphis forbesi Species 0.000 description 1
- 241001095118 Aphis pomi Species 0.000 description 1
- 241000496365 Aphis sambuci Species 0.000 description 1
- 241000726735 Aphis schneideri Species 0.000 description 1
- 241000273311 Aphis spiraecola Species 0.000 description 1
- 241001611610 Aphthona Species 0.000 description 1
- 241000533363 Apion Species 0.000 description 1
- 241001227591 Apogonia Species 0.000 description 1
- 241000511861 Aproaerema Species 0.000 description 1
- 101100301834 Arabidopsis thaliana RH44 gene Proteins 0.000 description 1
- 241000838579 Arboridia Species 0.000 description 1
- 241001002469 Archips Species 0.000 description 1
- 241001002470 Archips argyrospila Species 0.000 description 1
- 241001423665 Archips fuscocupreana Species 0.000 description 1
- 241001162025 Archips podana Species 0.000 description 1
- 241001423656 Archips rosana Species 0.000 description 1
- 241001480748 Argas Species 0.000 description 1
- 241001480752 Argas persicus Species 0.000 description 1
- 241000238888 Argasidae Species 0.000 description 1
- 241001203923 Argyresthia Species 0.000 description 1
- 241001574902 Argyroploce Species 0.000 description 1
- 241000384127 Argyrotaenia Species 0.000 description 1
- 241001525898 Argyrotaenia velutinana Species 0.000 description 1
- 241001250138 Arilus Species 0.000 description 1
- 241000237518 Arion Species 0.000 description 1
- 241000692821 Arion intermedius Species 0.000 description 1
- 241000722809 Armadillidium vulgare Species 0.000 description 1
- 240000005506 Artocarpus anisophyllus Species 0.000 description 1
- 241000244186 Ascaris Species 0.000 description 1
- 241000244185 Ascaris lumbricoides Species 0.000 description 1
- 240000006914 Aspalathus linearis Species 0.000 description 1
- 244000003416 Asparagus officinalis Species 0.000 description 1
- 235000005340 Asparagus officinalis Nutrition 0.000 description 1
- 241000668391 Aspidiella Species 0.000 description 1
- 241000387313 Aspidiotus Species 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 241001437124 Atanus Species 0.000 description 1
- 241001503477 Athalia rosae Species 0.000 description 1
- 241001243567 Atlanticus Species 0.000 description 1
- 241001174347 Atomaria Species 0.000 description 1
- 241000726103 Atta Species 0.000 description 1
- 241000281795 Atta capiguara Species 0.000 description 1
- 241000908426 Atta sexdens Species 0.000 description 1
- 241000131286 Attagenus Species 0.000 description 1
- 241000909014 Aulacaspis yasumatsui Species 0.000 description 1
- 241000902805 Aulacophora Species 0.000 description 1
- 241000322350 Austroasca viridigrisea Species 0.000 description 1
- 241001367053 Autographa gamma Species 0.000 description 1
- 241001367035 Autographa nigrisigna Species 0.000 description 1
- 239000005878 Azadirachtin Substances 0.000 description 1
- 239000005730 Azoxystrobin Substances 0.000 description 1
- 241000193363 Bacillus thuringiensis serovar aizawai Species 0.000 description 1
- 241000193365 Bacillus thuringiensis serovar israelensis Species 0.000 description 1
- 241001147758 Bacillus thuringiensis serovar kurstaki Species 0.000 description 1
- 241000193369 Bacillus thuringiensis serovar tenebrionis Species 0.000 description 1
- 241001124181 Bactrocera dorsalis Species 0.000 description 1
- 241001490249 Bactrocera oleae Species 0.000 description 1
- 241001579871 Bedellia Species 0.000 description 1
- 241000580217 Belonolaimus Species 0.000 description 1
- 239000005734 Benalaxyl Substances 0.000 description 1
- 239000005735 Benalaxyl-M Substances 0.000 description 1
- 239000005736 Benthiavalicarb Substances 0.000 description 1
- 239000005737 Benzovindiflupyr Substances 0.000 description 1
- 239000005884 Beta-Cyfluthrin Substances 0.000 description 1
- 241001142392 Bibio Species 0.000 description 1
- 239000005653 Bifenazate Substances 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- 241000237359 Biomphalaria Species 0.000 description 1
- 241001148506 Bitylenchus dubius Species 0.000 description 1
- 241000237519 Bivalvia Species 0.000 description 1
- 241001573716 Blaniulus guttulatus Species 0.000 description 1
- 241000238659 Blatta Species 0.000 description 1
- 241000238658 Blattella Species 0.000 description 1
- 241000238657 Blattella germanica Species 0.000 description 1
- 241001674044 Blattodea Species 0.000 description 1
- 241000929635 Blissus Species 0.000 description 1
- 241001629132 Blissus leucopterus Species 0.000 description 1
- 241001273385 Boeremia lycopersici Species 0.000 description 1
- 241001136816 Bombus <genus> Species 0.000 description 1
- 241001350395 Bonagota Species 0.000 description 1
- 241001622619 Borbo cinnara Species 0.000 description 1
- 239000005739 Bordeaux mixture Substances 0.000 description 1
- 241000322476 Bovicola bovis Species 0.000 description 1
- 241000273316 Brachycaudus Species 0.000 description 1
- 241000256422 Brachycaudus lateralis Species 0.000 description 1
- 241000272639 Brachycaudus mimeuri Species 0.000 description 1
- 241000256548 Brachycaudus prunicola Species 0.000 description 1
- 241001088081 Brachycolus Species 0.000 description 1
- 241001093996 Brachycorynella asparagi Species 0.000 description 1
- 241000204760 Brachymyrmex Species 0.000 description 1
- 235000003351 Brassica cretica Nutrition 0.000 description 1
- 235000003343 Brassica rupestris Nutrition 0.000 description 1
- 241000982105 Brevicoryne brassicae Species 0.000 description 1
- 241001643374 Brevipalpus Species 0.000 description 1
- 241001643371 Brevipalpus phoenicis Species 0.000 description 1
- 239000005741 Bromuconazole Substances 0.000 description 1
- LVDKZNITIUWNER-UHFFFAOYSA-N Bronopol Chemical compound OCC(Br)(CO)[N+]([O-])=O LVDKZNITIUWNER-UHFFFAOYSA-N 0.000 description 1
- 241001325378 Bruchus Species 0.000 description 1
- 241001414203 Bruchus lentis Species 0.000 description 1
- 241001414201 Bruchus pisorum Species 0.000 description 1
- 241001388466 Bruchus rufimanus Species 0.000 description 1
- 241000398201 Bryobia praetiosa Species 0.000 description 1
- 241001517925 Bucculatrix Species 0.000 description 1
- 241000041029 Bulinus Species 0.000 description 1
- 241000931178 Bunostomum Species 0.000 description 1
- 241001491790 Bupalus piniaria Species 0.000 description 1
- 239000005742 Bupirimate Substances 0.000 description 1
- 241000243770 Bursaphelenchus Species 0.000 description 1
- 241000661267 Busseola Species 0.000 description 1
- FIPWRIJSWJWJAI-UHFFFAOYSA-N Butyl carbitol 6-propylpiperonyl ether Chemical compound C1=C(CCC)C(COCCOCCOCCCC)=CC2=C1OCO2 FIPWRIJSWJWJAI-UHFFFAOYSA-N 0.000 description 1
- 101150111062 C gene Proteins 0.000 description 1
- LSGCKAKHASGTSY-QGOAFFKASA-N C(#N)C=1C=CC(=C(OCC2=C(C=CC=C2)/C(/C(=O)OC)=C\OC)C=1)C Chemical compound C(#N)C=1C=CC(=C(OCC2=C(C=CC=C2)/C(/C(=O)OC)=C\OC)C=1)C LSGCKAKHASGTSY-QGOAFFKASA-N 0.000 description 1
- QGTOTYJSCYHYFK-FWKSHIOASA-N CC(C(=O)OCOC=1C(=NC=CC1OC)C(NC1C(O[C@H]([C@@H]([C@H](C(OC1)=O)CC1=CC=CC=C1)OC(C(C)C)=O)C)=O)=O)C Chemical compound CC(C(=O)OCOC=1C(=NC=CC1OC)C(NC1C(O[C@H]([C@@H]([C@H](C(OC1)=O)CC1=CC=CC=C1)OC(C(C)C)=O)C)=O)=O)C QGTOTYJSCYHYFK-FWKSHIOASA-N 0.000 description 1
- CXHMHZIDRGJNSL-UHFFFAOYSA-N CC(F)(F)CNC(=O)c1ccc2nn(cc2c1)-c1cccnc1 Chemical compound CC(F)(F)CNC(=O)c1ccc2nn(cc2c1)-c1cccnc1 CXHMHZIDRGJNSL-UHFFFAOYSA-N 0.000 description 1
- 102100026049 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Human genes 0.000 description 1
- LGXIALVCQFVBBF-UHFFFAOYSA-N COC(=O)NNC(=O)c1ccc2nn(cc2c1)-c1cccnc1 Chemical compound COC(=O)NNC(=O)c1ccc2nn(cc2c1)-c1cccnc1 LGXIALVCQFVBBF-UHFFFAOYSA-N 0.000 description 1
- 241000710133 Cacao yellow mosaic virus Species 0.000 description 1
- 241001212014 Cacoecia Species 0.000 description 1
- 241000526185 Cacopsylla Species 0.000 description 1
- 241000599742 Cacopsylla fulguralis Species 0.000 description 1
- 241000608031 Cactoblastis cactorum Species 0.000 description 1
- 239000006009 Calcium phosphide Substances 0.000 description 1
- 241001630923 Callidiellum Species 0.000 description 1
- 241000356702 Calliptamus italicus Species 0.000 description 1
- 241001163610 Callopistria floridensis Species 0.000 description 1
- 241001313742 Callosobruchus chinensis Species 0.000 description 1
- 241000906761 Calocoris Species 0.000 description 1
- 241001521494 Cameraria ohridella Species 0.000 description 1
- 241000722666 Camponotus Species 0.000 description 1
- 241001491932 Camponotus atriceps Species 0.000 description 1
- 241000426451 Camponotus modoc Species 0.000 description 1
- 241001491934 Camponotus pennsylvanicus Species 0.000 description 1
- 241000613201 Campylomma livida Species 0.000 description 1
- 241000222120 Candida <Saccharomycetales> Species 0.000 description 1
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 description 1
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 description 1
- 241001094772 Capitophorus Species 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 239000005745 Captan Substances 0.000 description 1
- 239000005746 Carboxin Substances 0.000 description 1
- 241000076479 Cardiocondyla nuda Species 0.000 description 1
- 241000219173 Carica Species 0.000 description 1
- 241000219172 Caricaceae Species 0.000 description 1
- 241000260534 Carpoglyphidae Species 0.000 description 1
- 241000260547 Carpoglyphus Species 0.000 description 1
- 241001347512 Carposina Species 0.000 description 1
- 241001347511 Carposina sasakii Species 0.000 description 1
- 241001130355 Cassida nebulosa Species 0.000 description 1
- 241000252254 Catostomidae Species 0.000 description 1
- 241000781521 Cavelerius Species 0.000 description 1
- 241001427143 Cavelerius excavatus Species 0.000 description 1
- GYDLUVSMRCNDTQ-UHFFFAOYSA-N Cc1cc(ccc1OCc1c(cccc1-n1nnn(C)c1=O)C1CC1)-c1ccn(C)n1 Chemical compound Cc1cc(ccc1OCc1c(cccc1-n1nnn(C)c1=O)C1CC1)-c1ccn(C)n1 GYDLUVSMRCNDTQ-UHFFFAOYSA-N 0.000 description 1
- PYMSONKRELFQSE-UHFFFAOYSA-N Cc1cccc(c1COc1nc(cs1)-c1ccc(Cl)cc1)-n1nnn(C)c1=O Chemical compound Cc1cccc(c1COc1nc(cs1)-c1ccc(Cl)cc1)-n1nnn(C)c1=O PYMSONKRELFQSE-UHFFFAOYSA-N 0.000 description 1
- QYDSAKLKVOSFCL-UHFFFAOYSA-N Cc1cnc(CNC(=O)c2ccc3nn(cc3c2)-c2cccnc2)cn1 Chemical compound Cc1cnc(CNC(=O)c2ccc3nn(cc3c2)-c2cccnc2)cn1 QYDSAKLKVOSFCL-UHFFFAOYSA-N 0.000 description 1
- 241001552877 Cediopsylla Species 0.000 description 1
- 229940123982 Cell wall synthesis inhibitor Drugs 0.000 description 1
- 241000717851 Cephus Species 0.000 description 1
- 241000255579 Ceratitis capitata Species 0.000 description 1
- 241001098608 Ceratophyllus Species 0.000 description 1
- 241000134979 Ceratovacuna lanigera Species 0.000 description 1
- 240000005099 Cercis occidentalis Species 0.000 description 1
- 241001343163 Cercospora sorghicola Species 0.000 description 1
- 241000630083 Ceroplastes ceriferus Species 0.000 description 1
- 241000543463 Ceroplastes destructor Species 0.000 description 1
- 241001124201 Cerotoma trifurcata Species 0.000 description 1
- 241001121020 Cetonia aurata Species 0.000 description 1
- 241000896076 Ceuthophilus Species 0.000 description 1
- 241001399348 Ceutorhynchus napi Species 0.000 description 1
- 241000893172 Chabertia Species 0.000 description 1
- 241000260230 Chaetocnema aridula Species 0.000 description 1
- 241001087583 Chaetocnema tibialis Species 0.000 description 1
- 241001094951 Chaetosiphon Species 0.000 description 1
- 241000604356 Chamaepsila rosae Species 0.000 description 1
- 108091006146 Channels Proteins 0.000 description 1
- 241000426499 Chilo Species 0.000 description 1
- 241000661337 Chilo partellus Species 0.000 description 1
- 241000426497 Chilo suppressalis Species 0.000 description 1
- 241000258920 Chilopoda Species 0.000 description 1
- 241000668556 Chionaspis Species 0.000 description 1
- 239000005945 Chlorpyrifos-methyl Substances 0.000 description 1
- 241001340573 Choreutis pariana Species 0.000 description 1
- 241000255945 Choristoneura Species 0.000 description 1
- 241000967659 Choristoneura conflictana Species 0.000 description 1
- 241000255942 Choristoneura fumiferana Species 0.000 description 1
- 241001622943 Choristoneura longicellana Species 0.000 description 1
- 241001124562 Choristoneura rosaceana Species 0.000 description 1
- 241000756804 Chortoicetes terminifera Species 0.000 description 1
- 239000005887 Chromafenozide Substances 0.000 description 1
- 241000118402 Chromaphis juglandicola Species 0.000 description 1
- 241001364933 Chrysodeixis eriosoma Species 0.000 description 1
- 241000983417 Chrysomya bezziana Species 0.000 description 1
- 241001097338 Cicadulina Species 0.000 description 1
- 241001635683 Cimex hemipterus Species 0.000 description 1
- 241001327638 Cimex lectularius Species 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 241001672694 Citrus reticulata Species 0.000 description 1
- 240000000560 Citrus x paradisi Species 0.000 description 1
- BZSZIAPWBMBDHX-UHFFFAOYSA-N ClC1=C(C=CC(=C1)Cl)N1N=C(C=C1)OCC=C(/C(/C(=O)NC)=NOC)C Chemical compound ClC1=C(C=CC(=C1)Cl)N1N=C(C=C1)OCC=C(/C(/C(=O)NC)=NOC)C BZSZIAPWBMBDHX-UHFFFAOYSA-N 0.000 description 1
- GVUOBBKPMNKLHO-UHFFFAOYSA-N ClC=1C(=C(C=CC1)N1N=NN(C1=O)C)COC=1SC=C(N1)C1=CC=C(C=C1)C Chemical compound ClC=1C(=C(C=CC1)N1N=NN(C1=O)C)COC=1SC=C(N1)C1=CC=C(C=C1)C GVUOBBKPMNKLHO-UHFFFAOYSA-N 0.000 description 1
- NGHAOSCNUNCMLH-UHFFFAOYSA-N ClCC1(C(C(CC1)CC1=CC=C(C=C1)C)(O)CN1N=CN=C1)C Chemical compound ClCC1(C(C(CC1)CC1=CC=C(C=C1)C)(O)CN1N=CN=C1)C NGHAOSCNUNCMLH-UHFFFAOYSA-N 0.000 description 1
- 241001152840 Cleonus Species 0.000 description 1
- 239000005654 Clofentezine Substances 0.000 description 1
- JSPNFPTTXLDNGF-UHFFFAOYSA-N Cn1nnn(-c2cccc(F)c2COc2ccn(n2)-c2ccc(Cl)cc2Cl)c1=O Chemical compound Cn1nnn(-c2cccc(F)c2COc2ccn(n2)-c2ccc(Cl)cc2Cl)c1=O JSPNFPTTXLDNGF-UHFFFAOYSA-N 0.000 description 1
- 241001350387 Cnephasia Species 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 241001479453 Coccus pseudomagnoliarum Species 0.000 description 1
- 241000933851 Cochliomyia Species 0.000 description 1
- 241000933849 Cochliomyia macellaria Species 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 241000689390 Coleophora Species 0.000 description 1
- 241000143939 Colias eurytheme Species 0.000 description 1
- 241001427559 Collembola Species 0.000 description 1
- 241001001953 Colletotrichum pyricola Species 0.000 description 1
- 241000106022 Colomerus vitis Species 0.000 description 1
- 241000218631 Coniferophyta Species 0.000 description 1
- 241000683561 Conoderus Species 0.000 description 1
- 241001476526 Conopomorpha Species 0.000 description 1
- 241000532667 Conotrachelus Species 0.000 description 1
- 241000532642 Conotrachelus nenuphar Species 0.000 description 1
- 241001663470 Contarinia <gall midge> Species 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 241000582510 Copitarsia Species 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- JJLJMEJHUUYSSY-UHFFFAOYSA-L Copper hydroxide Chemical compound [OH-].[OH-].[Cu+2] JJLJMEJHUUYSSY-UHFFFAOYSA-L 0.000 description 1
- 239000005750 Copper hydroxide Substances 0.000 description 1
- 239000005752 Copper oxychloride Substances 0.000 description 1
- 241001509964 Coptotermes Species 0.000 description 1
- 241001250591 Coptotermes acinaciformis Species 0.000 description 1
- 241001509962 Coptotermes formosanus Species 0.000 description 1
- 241000616864 Coptotermes gestroi Species 0.000 description 1
- 235000011777 Corchorus aestuans Nutrition 0.000 description 1
- 240000004792 Corchorus capsularis Species 0.000 description 1
- 235000010862 Corchorus capsularis Nutrition 0.000 description 1
- 241000993412 Corcyra cephalonica Species 0.000 description 1
- 241000304165 Cordylobia anthropophaga Species 0.000 description 1
- 241000422839 Cornitermes cumulans Species 0.000 description 1
- 241001074773 Cortinarius vespertinus Species 0.000 description 1
- 241001565242 Corythucha arcuata Species 0.000 description 1
- 241001212536 Cosmopolites Species 0.000 description 1
- 241000500845 Costelytra zealandica Species 0.000 description 1
- 241001340508 Crambus Species 0.000 description 1
- 241001157797 Crematogaster <genus> Species 0.000 description 1
- 241000720930 Creontiades Species 0.000 description 1
- 241001255091 Criconema Species 0.000 description 1
- 241001267662 Criconemoides Species 0.000 description 1
- 241001267664 Criconemoides informis Species 0.000 description 1
- 241001574015 Crocidosema Species 0.000 description 1
- 241000592377 Cryptolestes ferrugineus Species 0.000 description 1
- 241001136984 Cryptophlebia Species 0.000 description 1
- 241001152743 Cryptorhynchus Species 0.000 description 1
- 241000866584 Cryptotermes Species 0.000 description 1
- 241001506147 Cryptotermes brevis Species 0.000 description 1
- 241001470534 Cryptotermes cavifrons Species 0.000 description 1
- 241000242268 Ctenicera Species 0.000 description 1
- 241000258922 Ctenocephalides Species 0.000 description 1
- 241000490513 Ctenocephalides canis Species 0.000 description 1
- 241001124552 Ctenolepisma Species 0.000 description 1
- 241001197102 Ctenotus Species 0.000 description 1
- 241000724252 Cucumber mosaic virus Species 0.000 description 1
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 1
- 241000219122 Cucurbita Species 0.000 description 1
- 240000004244 Cucurbita moschata Species 0.000 description 1
- 241000256054 Culex <genus> Species 0.000 description 1
- 241000144347 Culex nigripalpus Species 0.000 description 1
- 241000256059 Culex pipiens Species 0.000 description 1
- 241000256057 Culex quinquefasciatus Species 0.000 description 1
- 241000256061 Culex tarsalis Species 0.000 description 1
- 241000256060 Culex tritaeniorhynchus Species 0.000 description 1
- 241000208506 Culicoides furens Species 0.000 description 1
- 241000036151 Culiseta melanura Species 0.000 description 1
- 241000721021 Curculio Species 0.000 description 1
- 241000692095 Cuterebra Species 0.000 description 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 description 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 description 1
- 239000005754 Cyazofamid Substances 0.000 description 1
- 241001156075 Cyclocephala Species 0.000 description 1
- 241001573495 Cydalima Species 0.000 description 1
- 241001634817 Cydia Species 0.000 description 1
- 241001652531 Cydia latiferreana Species 0.000 description 1
- 241001635274 Cydia pomonella Species 0.000 description 1
- 239000005755 Cyflufenamid Substances 0.000 description 1
- 241001183634 Cylindrocopturus Species 0.000 description 1
- 239000005756 Cymoxanil Substances 0.000 description 1
- 239000005946 Cypermethrin Substances 0.000 description 1
- 239000005757 Cyproconazole Substances 0.000 description 1
- 239000005758 Cyprodinil Substances 0.000 description 1
- 239000005891 Cyromazine Substances 0.000 description 1
- 241001090151 Cyrtopeltis Species 0.000 description 1
- 206010011732 Cyst Diseases 0.000 description 1
- 201000003808 Cystic echinococcosis Diseases 0.000 description 1
- 241001161399 Dactylispa Species 0.000 description 1
- 244000033273 Dahlia variabilis Species 0.000 description 1
- 241000801939 Dalaca Species 0.000 description 1
- 241001260003 Dalbulus Species 0.000 description 1
- 241001259996 Dalbulus maidis Species 0.000 description 1
- 241000268912 Damalinia Species 0.000 description 1
- 241001201722 Dargida Species 0.000 description 1
- 241000969022 Dasineura Species 0.000 description 1
- 241001051735 Dasineura oxycoccana Species 0.000 description 1
- 241000394734 Dasychira pinicola Species 0.000 description 1
- 241000279989 Dasypterus intermedius Species 0.000 description 1
- 241001351082 Datana integerrima Species 0.000 description 1
- 239000005644 Dazomet Substances 0.000 description 1
- 241001161382 Dectes texanus Species 0.000 description 1
- 241000084475 Delia antiqua Species 0.000 description 1
- 241001585354 Delia coarctata Species 0.000 description 1
- 241001414892 Delia radicum Species 0.000 description 1
- 239000005892 Deltamethrin Substances 0.000 description 1
- 241001128004 Demodex Species 0.000 description 1
- 241001127981 Demodicidae Species 0.000 description 1
- 241000859566 Dendrobium suzukii Species 0.000 description 1
- 241001631715 Dendrolimus Species 0.000 description 1
- 241001631712 Dendrolimus pini Species 0.000 description 1
- 241001309417 Dendrolimus sibiricus Species 0.000 description 1
- 208000006558 Dental Calculus Diseases 0.000 description 1
- 241001480824 Dermacentor Species 0.000 description 1
- 241000119571 Dermacentor silvarum Species 0.000 description 1
- 241001481695 Dermanyssus gallinae Species 0.000 description 1
- 241001124144 Dermaptera Species 0.000 description 1
- 241000202828 Dermatobia hominis Species 0.000 description 1
- 241001641895 Dermestes Species 0.000 description 1
- 241001300085 Deroceras Species 0.000 description 1
- 241001641949 Desmia funeralis Species 0.000 description 1
- 241000489975 Diabrotica Species 0.000 description 1
- 241000916723 Diabrotica longicornis Species 0.000 description 1
- 241000916731 Diabrotica speciosa Species 0.000 description 1
- 241000489973 Diabrotica undecimpunctata Species 0.000 description 1
- 241000489977 Diabrotica virgifera Species 0.000 description 1
- 241000108082 Dialeurodes Species 0.000 description 1
- 241001000394 Diaphania hyalinata Species 0.000 description 1
- 241001012951 Diaphania nitidalis Species 0.000 description 1
- 241000526124 Diaphorina Species 0.000 description 1
- 241000721035 Diaprepes Species 0.000 description 1
- 241000586568 Diaspidiotus perniciosus Species 0.000 description 1
- 241000643949 Diaspis <angiosperm> Species 0.000 description 1
- 241000879145 Diatraea grandiosella Species 0.000 description 1
- 241000122106 Diatraea saccharalis Species 0.000 description 1
- 241001549096 Dichelops furcatus Species 0.000 description 1
- MDNWOSOZYLHTCG-UHFFFAOYSA-N Dichlorophen Chemical compound OC1=CC=C(Cl)C=C1CC1=CC(Cl)=CC=C1O MDNWOSOZYLHTCG-UHFFFAOYSA-N 0.000 description 1
- 241000508744 Dichromothrips Species 0.000 description 1
- 241000162400 Dicladispa armigera Species 0.000 description 1
- 241000577452 Dicrocoelium Species 0.000 description 1
- 241000180412 Dictyocaulus filaria Species 0.000 description 1
- 241001480349 Diestrammena asynamora Species 0.000 description 1
- 239000005759 Diethofencarb Substances 0.000 description 1
- 239000005760 Difenoconazole Substances 0.000 description 1
- LBGPXIPGGRQBJW-UHFFFAOYSA-N Difenzoquat Chemical compound C[N+]=1N(C)C(C=2C=CC=CC=2)=CC=1C1=CC=CC=C1 LBGPXIPGGRQBJW-UHFFFAOYSA-N 0.000 description 1
- 239000005893 Diflubenzuron Substances 0.000 description 1
- 239000005947 Dimethoate Substances 0.000 description 1
- 239000005762 Dimoxystrobin Substances 0.000 description 1
- HDWLUGYOLUHEMN-UHFFFAOYSA-N Dinobuton Chemical compound CCC(C)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1OC(=O)OC(C)C HDWLUGYOLUHEMN-UHFFFAOYSA-N 0.000 description 1
- 241001212653 Diocalandra Species 0.000 description 1
- 241001212652 Diocalandra frumenti Species 0.000 description 1
- 241001163650 Diphthera festiva Species 0.000 description 1
- 241000866683 Diphyllobothrium latum Species 0.000 description 1
- 241000258963 Diplopoda Species 0.000 description 1
- 241000511318 Diprion Species 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- 241000399934 Ditylenchus Species 0.000 description 1
- 241000399948 Ditylenchus destructor Species 0.000 description 1
- 241001080889 Dociostaurus maroccanus Species 0.000 description 1
- 239000005766 Dodine Substances 0.000 description 1
- 241000932610 Dolichodorus Species 0.000 description 1
- 241000256868 Dolichovespula maculata Species 0.000 description 1
- 241000520388 Dorymyrmex Species 0.000 description 1
- 241001319090 Dracunculus medinensis Species 0.000 description 1
- 241001465185 Drechslera avenae Species 0.000 description 1
- 241000193907 Dreissena Species 0.000 description 1
- 241001274799 Dreyfusia nordmannianae Species 0.000 description 1
- 241001274798 Dreyfusia piceae Species 0.000 description 1
- 241001595884 Drosicha Species 0.000 description 1
- 241000255581 Drosophila <fruit fly, genus> Species 0.000 description 1
- 241000255447 Drosophila bromeliae Species 0.000 description 1
- 241001220350 Dryocosmus kuriphilus Species 0.000 description 1
- 241001581005 Dysaphis Species 0.000 description 1
- 241001581006 Dysaphis plantaginea Species 0.000 description 1
- 241001088941 Dysaphis radicola Species 0.000 description 1
- 241001425477 Dysdercus Species 0.000 description 1
- 241001425472 Dysdercus cingulatus Species 0.000 description 1
- 241001516600 Dysmicoccus Species 0.000 description 1
- AIGRXSNSLVJMEA-UHFFFAOYSA-N EPN Chemical compound C=1C=CC=CC=1P(=S)(OCC)OC1=CC=C([N+]([O-])=O)C=C1 AIGRXSNSLVJMEA-UHFFFAOYSA-N 0.000 description 1
- 241000241133 Earias Species 0.000 description 1
- 241000353522 Earias insulana Species 0.000 description 1
- 241001572697 Earias vittella Species 0.000 description 1
- 241001575036 Ecdytolopha Species 0.000 description 1
- 241000244170 Echinococcus granulosus Species 0.000 description 1
- 241000244163 Echinococcus multilocularis Species 0.000 description 1
- 241001313316 Echinothrips americanus Species 0.000 description 1
- 241000051717 Edessa Species 0.000 description 1
- 241001585089 Egira Species 0.000 description 1
- 240000003133 Elaeis guineensis Species 0.000 description 1
- 244000127993 Elaeis melanococca Species 0.000 description 1
- 241000400698 Elasmopalpus lignosellus Species 0.000 description 1
- 241000661279 Eldana Species 0.000 description 1
- 240000002943 Elettaria cardamomum Species 0.000 description 1
- 241000125118 Elsinoe fawcettii Species 0.000 description 1
- YUGWDVYLFSETPE-JLHYYAGUSA-N Empenthrin Chemical compound CC\C=C(/C)C(C#C)OC(=O)C1C(C=C(C)C)C1(C)C YUGWDVYLFSETPE-JLHYYAGUSA-N 0.000 description 1
- 241000995023 Empoasca Species 0.000 description 1
- 241000995027 Empoasca fabae Species 0.000 description 1
- 241000143565 Enaphalodes rufulus Species 0.000 description 1
- 241001608224 Ennomos subsignaria Species 0.000 description 1
- 241000498255 Enterobius vermicularis Species 0.000 description 1
- 241000661281 Eoreuma Species 0.000 description 1
- 241000488562 Eotetranychus Species 0.000 description 1
- 241000630736 Ephestia Species 0.000 description 1
- 241001555556 Ephestia elutella Species 0.000 description 1
- 241000669047 Epidiaspis leperii Species 0.000 description 1
- 241001301805 Epilachna Species 0.000 description 1
- 241000462639 Epilachna varivestis Species 0.000 description 1
- 241001147395 Epinotia Species 0.000 description 1
- 241000098279 Epinotia aporema Species 0.000 description 1
- 241000918644 Epiphyas postvittana Species 0.000 description 1
- 241000079320 Epitrimerus Species 0.000 description 1
- 241000303278 Epitrix Species 0.000 description 1
- 241001183322 Epitrix hirtipennis Species 0.000 description 1
- 241001491690 Erannis defoliaria Species 0.000 description 1
- 241000473921 Erannis tiliaria Species 0.000 description 1
- 241001072257 Eratigena agrestis Species 0.000 description 1
- 244000042139 Eria javanica Species 0.000 description 1
- 241001251922 Erionota thrax Species 0.000 description 1
- 241001221110 Eriophyidae Species 0.000 description 1
- 241000917107 Eriosoma lanigerum Species 0.000 description 1
- 241001515686 Erythroneura Species 0.000 description 1
- 239000005895 Esfenvalerate Substances 0.000 description 1
- 108090000371 Esterases Proteins 0.000 description 1
- 239000005961 Ethoprophos Substances 0.000 description 1
- 241001486247 Etiella Species 0.000 description 1
- 239000005896 Etofenprox Substances 0.000 description 1
- 239000005769 Etridiazole Substances 0.000 description 1
- 241001201696 Eulia Species 0.000 description 1
- 241000903448 Eurycotis floridana Species 0.000 description 1
- 241000515838 Eurygaster Species 0.000 description 1
- 241000515837 Eurygaster integriceps Species 0.000 description 1
- 241000098297 Euschistus Species 0.000 description 1
- 241000098295 Euschistus heros Species 0.000 description 1
- 241001619920 Euschistus servus Species 0.000 description 1
- 241001034433 Eutetranychus Species 0.000 description 1
- 241001585293 Euxoa Species 0.000 description 1
- 101150013030 FAN1 gene Proteins 0.000 description 1
- UMZPRVJSFISKMD-UHFFFAOYSA-N FC(F)(F)CNC(=O)c1cccc2nn(cc12)-c1cccnc1 Chemical compound FC(F)(F)CNC(=O)c1cccc2nn(cc12)-c1cccnc1 UMZPRVJSFISKMD-UHFFFAOYSA-N 0.000 description 1
- OTDPWLGCOBLOJJ-UHFFFAOYSA-N FC(OC=1C(=C(C=CC1)N1N=NN(C1=O)C)COC1=C(C=C(C=C1)C1=NN(C=C1)C)C)F Chemical compound FC(OC=1C(=C(C=CC1)N1N=NN(C1=O)C)COC1=C(C=C(C=C1)C1=NN(C=C1)C)C)F OTDPWLGCOBLOJJ-UHFFFAOYSA-N 0.000 description 1
- SDLRQSZGJPTWPT-UHFFFAOYSA-N FC1(F)CC1CNC(=O)c1ccc2nn(cc2c1)-c1cccnc1 Chemical compound FC1(F)CC1CNC(=O)c1ccc2nn(cc2c1)-c1cccnc1 SDLRQSZGJPTWPT-UHFFFAOYSA-N 0.000 description 1
- 241000371383 Fannia Species 0.000 description 1
- 241000953886 Fannia canicularis Species 0.000 description 1
- 241000233488 Feltia Species 0.000 description 1
- 239000005774 Fenamidone Substances 0.000 description 1
- 239000005958 Fenamiphos (aka phenamiphos) Substances 0.000 description 1
- 239000005656 Fenazaquin Substances 0.000 description 1
- 239000005775 Fenbuconazole Substances 0.000 description 1
- 239000005776 Fenhexamid Substances 0.000 description 1
- AYBALPYBYZFKDS-OLZOCXBDSA-N Fenitropan Chemical compound CC(=O)OC[C@@H]([N+]([O-])=O)[C@@H](OC(C)=O)C1=CC=CC=C1 AYBALPYBYZFKDS-OLZOCXBDSA-N 0.000 description 1
- 239000005898 Fenoxycarb Substances 0.000 description 1
- 239000005777 Fenpropidin Substances 0.000 description 1
- 239000005779 Fenpyrazamine Substances 0.000 description 1
- 239000005657 Fenpyroximate Substances 0.000 description 1
- PNVJTZOFSHSLTO-UHFFFAOYSA-N Fenthion Chemical compound COP(=S)(OC)OC1=CC=C(SC)C(C)=C1 PNVJTZOFSHSLTO-UHFFFAOYSA-N 0.000 description 1
- 241000218218 Ficus <angiosperm> Species 0.000 description 1
- 244000235816 Fimbristylis cinnamometorum Species 0.000 description 1
- 239000005780 Fluazinam Substances 0.000 description 1
- 239000005901 Flubendiamide Substances 0.000 description 1
- 239000005781 Fludioxonil Substances 0.000 description 1
- 239000005782 Fluopicolide Substances 0.000 description 1
- 239000005902 Flupyradifurone Substances 0.000 description 1
- 239000005786 Flutolanil Substances 0.000 description 1
- 239000005789 Folpet Substances 0.000 description 1
- 241000720914 Forficula auricularia Species 0.000 description 1
- 239000005948 Formetanate Substances 0.000 description 1
- 241001251094 Formica Species 0.000 description 1
- 239000005790 Fosetyl Substances 0.000 description 1
- 239000005959 Fosthiazate Substances 0.000 description 1
- 240000009088 Fragaria x ananassa Species 0.000 description 1
- 241000189565 Frankliniella Species 0.000 description 1
- 241000927584 Frankliniella occidentalis Species 0.000 description 1
- 241000189591 Frankliniella tritici Species 0.000 description 1
- 239000005791 Fuberidazole Substances 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 108091006027 G proteins Proteins 0.000 description 1
- 102000030782 GTP binding Human genes 0.000 description 1
- 108091000058 GTP-Binding Proteins 0.000 description 1
- 241000585112 Galba Species 0.000 description 1
- 241000255896 Galleria mellonella Species 0.000 description 1
- 241000982383 Gametis jucunda Species 0.000 description 1
- 239000005903 Gamma-cyhalothrin Substances 0.000 description 1
- 241001057692 Geococcus coffeae Species 0.000 description 1
- 241000663951 Geocoris Species 0.000 description 1
- 241000938140 Geomyza Species 0.000 description 1
- 241000248126 Geophilus Species 0.000 description 1
- 241000224467 Giardia intestinalis Species 0.000 description 1
- 241001043186 Gibbium Species 0.000 description 1
- 241001125730 Globitermes Species 0.000 description 1
- 241001442498 Globodera Species 0.000 description 1
- 241001442497 Globodera rostochiensis Species 0.000 description 1
- 241000257324 Glossina <genus> Species 0.000 description 1
- 241000257326 Glossina fuscipes Species 0.000 description 1
- 241000257323 Glossina morsitans Species 0.000 description 1
- 241000257334 Glossina palpalis Species 0.000 description 1
- 241001502124 Glossina tachinoides Species 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 241000526126 Glycaspis Species 0.000 description 1
- 241001163576 Gnathocerus cornutus Species 0.000 description 1
- 240000000047 Gossypium barbadense Species 0.000 description 1
- 235000009429 Gossypium barbadense Nutrition 0.000 description 1
- 241001579964 Gracillaria Species 0.000 description 1
- 241001232715 Granaria Species 0.000 description 1
- 241001150406 Grapholita Species 0.000 description 1
- 241000923682 Grapholita funebrana Species 0.000 description 1
- 241001441330 Grapholita molesta Species 0.000 description 1
- 241001091440 Grossulariaceae Species 0.000 description 1
- 241001243091 Gryllotalpa Species 0.000 description 1
- 241000785585 Gryllotalpa africana Species 0.000 description 1
- 241000241125 Gryllotalpa gryllotalpa Species 0.000 description 1
- 241000238821 Gryllus Species 0.000 description 1
- 241000257232 Haematobia irritans Species 0.000 description 1
- 241000790933 Haematopinus Species 0.000 description 1
- 241000894055 Haematopinus eurysternus Species 0.000 description 1
- 241000670091 Haematopinus suis Species 0.000 description 1
- 241000243976 Haemonchus Species 0.000 description 1
- 241000243974 Haemonchus contortus Species 0.000 description 1
- 241000825557 Halyomorpha Species 0.000 description 1
- 241000825556 Halyomorpha halys Species 0.000 description 1
- 241001585276 Halysidota Species 0.000 description 1
- 241000730161 Haritalodes derogata Species 0.000 description 1
- 241001352371 Harrisina americana Species 0.000 description 1
- 244000020551 Helianthus annuus Species 0.000 description 1
- 241000510199 Helicoverpa assulta Species 0.000 description 1
- 241000256257 Heliothis Species 0.000 description 1
- 241001515776 Heliothis subflexa Species 0.000 description 1
- 241001351414 Hellula Species 0.000 description 1
- 241001148478 Hemicriconemoides Species 0.000 description 1
- 241001267658 Hemicycliophora Species 0.000 description 1
- 241001299252 Henosepilachna vigintioctomaculata Species 0.000 description 1
- 241001659688 Hercinothrips femoralis Species 0.000 description 1
- 241001000403 Herpetogramma licarsisalis Species 0.000 description 1
- 241000920462 Heterakis Species 0.000 description 1
- 241001480224 Heterodera Species 0.000 description 1
- 241000040487 Heterodera trifolii Species 0.000 description 1
- 241001176496 Heteronychus arator Species 0.000 description 1
- 241000590466 Heterotermes Species 0.000 description 1
- 241001387517 Heterotermes aureus Species 0.000 description 1
- 241000754671 Heterotermes longiceps Species 0.000 description 1
- 241001387505 Heterotermes tenuis Species 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 239000005661 Hexythiazox Substances 0.000 description 1
- 241000317608 Hieroglyphus Species 0.000 description 1
- 108010072039 Histidine kinase Proteins 0.000 description 1
- 241001288674 Holotrichia consanguinea Species 0.000 description 1
- 101000692362 Homo sapiens CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Proteins 0.000 description 1
- 101000615488 Homo sapiens Methyl-CpG-binding domain protein 2 Proteins 0.000 description 1
- 241000630740 Homoeosoma electellum Species 0.000 description 1
- 241000957299 Homona magnanima Species 0.000 description 1
- 241001417351 Hoplocampa Species 0.000 description 1
- 241000291719 Hoplocampa minuta Species 0.000 description 1
- 241000291732 Hoplocampa testudinea Species 0.000 description 1
- 241001032366 Hoplolaimus magnistylus Species 0.000 description 1
- 241001480803 Hyalomma Species 0.000 description 1
- 241001251778 Hyalomma truncatum Species 0.000 description 1
- 241001251909 Hyalopterus pruni Species 0.000 description 1
- 241000319560 Hydrellia Species 0.000 description 1
- 241000115042 Hylamorpha elegans Species 0.000 description 1
- 241001153231 Hylobius abietis Species 0.000 description 1
- 241000832180 Hylotrupes bajulus Species 0.000 description 1
- 241001464384 Hymenolepis nana Species 0.000 description 1
- 241001508558 Hypera Species 0.000 description 1
- 241001508570 Hypera brunneipennis Species 0.000 description 1
- 241001508566 Hypera postica Species 0.000 description 1
- 241000310291 Hyperomyzus lactucae Species 0.000 description 1
- 241001531327 Hyphantria cunea Species 0.000 description 1
- 241000257176 Hypoderma <fly> Species 0.000 description 1
- 241001095856 Hypomeces squamosus Species 0.000 description 1
- 241000577499 Hypothenemus Species 0.000 description 1
- 241001595209 Idiocerus Species 0.000 description 1
- 241000761334 Idioscopus Species 0.000 description 1
- 239000005795 Imazalil Substances 0.000 description 1
- 239000005566 Imazamox Substances 0.000 description 1
- PPCUNNLZTNMXFO-ACCUITESSA-N Imicyafos Chemical compound CCCSP(=O)(OCC)N1CCN(CC)\C1=N/C#N PPCUNNLZTNMXFO-ACCUITESSA-N 0.000 description 1
- FKWDSATZSMJRLC-UHFFFAOYSA-N Iminoctadine acetate Chemical compound CC([O-])=O.CC([O-])=O.CC([O-])=O.NC([NH3+])=NCCCCCCCC[NH2+]CCCCCCCCN=C(N)[NH3+] FKWDSATZSMJRLC-UHFFFAOYSA-N 0.000 description 1
- 241000204026 Incisitermes Species 0.000 description 1
- 239000005796 Ipconazole Substances 0.000 description 1
- 235000002678 Ipomoea batatas Nutrition 0.000 description 1
- 244000017020 Ipomoea batatas Species 0.000 description 1
- 239000005867 Iprodione Substances 0.000 description 1
- 239000005797 Iprovalicarb Substances 0.000 description 1
- 239000005798 Isofetamid Substances 0.000 description 1
- 241001149911 Isopoda Species 0.000 description 1
- 241000256602 Isoptera Species 0.000 description 1
- 244000045568 Ixeridium laevigatum Species 0.000 description 1
- 241000238681 Ixodes Species 0.000 description 1
- 241000922049 Ixodes holocyclus Species 0.000 description 1
- 241001569685 Ixodes minor Species 0.000 description 1
- 241001149946 Ixodes pacificus Species 0.000 description 1
- 241001480843 Ixodes ricinus Species 0.000 description 1
- 241000472347 Ixodes rubicundus Species 0.000 description 1
- 241000238703 Ixodes scapularis Species 0.000 description 1
- 241000238889 Ixodidae Species 0.000 description 1
- 241000397365 Javesella pellucida Species 0.000 description 1
- 241001002197 Juglans mollis Species 0.000 description 1
- 241000095517 Julus Species 0.000 description 1
- 241000896288 Kakothrips Species 0.000 description 1
- 241000400431 Keiferia lycopersicella Species 0.000 description 1
- 239000005800 Kresoxim-methyl Substances 0.000 description 1
- NWUWYYSKZYIQAE-ZBFHGGJFSA-N L-(R)-iprovalicarb Chemical compound CC(C)OC(=O)N[C@@H](C(C)C)C(=O)N[C@H](C)C1=CC=C(C)C=C1 NWUWYYSKZYIQAE-ZBFHGGJFSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 244000112675 Lablab purpureus Species 0.000 description 1
- 241000372024 Lacerta bilineata Species 0.000 description 1
- 241000208822 Lactuca Species 0.000 description 1
- 235000003228 Lactuca sativa Nutrition 0.000 description 1
- 241001658022 Lambdina fiscellaria fiscellaria Species 0.000 description 1
- 241001658020 Lambdina fiscellaria lugubrosa Species 0.000 description 1
- 241001470017 Laodelphax striatella Species 0.000 description 1
- 241001177160 Lasioderma Species 0.000 description 1
- 241000256686 Lasius <genus> Species 0.000 description 1
- 241000283797 Lasius interjectus Species 0.000 description 1
- 241001163604 Latheticus oryzae Species 0.000 description 1
- 241000416709 Lathyrus elongatus Species 0.000 description 1
- 241000041773 Latridius Species 0.000 description 1
- 241000238866 Latrodectus mactans Species 0.000 description 1
- 241000981121 Leguminivora glycinivorella Species 0.000 description 1
- 241001142635 Lema Species 0.000 description 1
- 241000219739 Lens Species 0.000 description 1
- 235000010666 Lens esculenta Nutrition 0.000 description 1
- 241000669027 Lepidosaphes Species 0.000 description 1
- 241000368289 Lepidosaphes ulmi Species 0.000 description 1
- 241000500881 Lepisma Species 0.000 description 1
- 241000258915 Leptinotarsa Species 0.000 description 1
- 241000258916 Leptinotarsa decemlineata Species 0.000 description 1
- 241000893124 Leptispa pygmaea Species 0.000 description 1
- 241001261797 Leptoconops Species 0.000 description 1
- 241000661345 Leptocorisa Species 0.000 description 1
- 241000629454 Leptocybe invasa Species 0.000 description 1
- 241000560153 Leptoglossus phyllopus Species 0.000 description 1
- 244000309549 Leptosphaeria pratensis Species 0.000 description 1
- 241001198950 Leptosphaerulina trifolii Species 0.000 description 1
- 241000016569 Lerodea eufala Species 0.000 description 1
- 241000086074 Leucinodes orbonalis Species 0.000 description 1
- 241001352367 Leucoma salicis Species 0.000 description 1
- 241000828880 Leucoptera <angiosperm> Species 0.000 description 1
- 241001578972 Leucoptera malifoliella Species 0.000 description 1
- 241001113970 Linognathus Species 0.000 description 1
- 241001113946 Linognathus vituli Species 0.000 description 1
- 241000403259 Liogenys Species 0.000 description 1
- 241000520391 Liometopum Species 0.000 description 1
- 241000272320 Lipaphis Species 0.000 description 1
- 241000594036 Liriomyza Species 0.000 description 1
- 241000594031 Liriomyza sativae Species 0.000 description 1
- 241000396080 Lissorhoptrus Species 0.000 description 1
- 241000004742 Lithophane antennata Species 0.000 description 1
- 241000532753 Lixus Species 0.000 description 1
- 241001261104 Lobesia botrana Species 0.000 description 1
- 241000254023 Locusta Species 0.000 description 1
- 241000254022 Locusta migratoria Species 0.000 description 1
- 241001220360 Longidorus Species 0.000 description 1
- 241001585360 Lophocampa Species 0.000 description 1
- 241000238865 Loxosceles reclusa Species 0.000 description 1
- 241000193982 Loxostege Species 0.000 description 1
- 241000363262 Loxostege cereralis Species 0.000 description 1
- 241000193981 Loxostege sticticalis Species 0.000 description 1
- 241000257166 Lucilia cuprina Species 0.000 description 1
- 241000736227 Lucilia sericata Species 0.000 description 1
- 239000005912 Lufenuron Substances 0.000 description 1
- 241000332820 Lycosa Species 0.000 description 1
- 241001177134 Lyctus Species 0.000 description 1
- 241001414826 Lygus Species 0.000 description 1
- 241001414823 Lygus hesperus Species 0.000 description 1
- 241000501345 Lygus lineolaris Species 0.000 description 1
- 241000721696 Lymantria Species 0.000 description 1
- 241001314285 Lymantria monacha Species 0.000 description 1
- 241000237354 Lymnaea Species 0.000 description 1
- 241001581015 Lyonetia clerkella Species 0.000 description 1
- 241001190650 Lyonetia prunifoliella Species 0.000 description 1
- 108091054455 MAP kinase family Proteins 0.000 description 1
- 241000766395 Maconellicoccus hirsutus Species 0.000 description 1
- 241001155765 Macrodactylus Species 0.000 description 1
- 241000273338 Macronyssidae Species 0.000 description 1
- 241000721715 Macrosiphum Species 0.000 description 1
- 241001094559 Macrosiphum californicum Species 0.000 description 1
- 241000721714 Macrosiphum euphorbiae Species 0.000 description 1
- 241000180172 Macrosiphum rosae Species 0.000 description 1
- 241001259998 Macrosteles quadrilineatus Species 0.000 description 1
- 241000927670 Mahanarva fimbriolata Species 0.000 description 1
- 241000255676 Malacosoma Species 0.000 description 1
- 241000255685 Malacosoma neustria Species 0.000 description 1
- 241001398048 Maladera Species 0.000 description 1
- 239000005949 Malathion Substances 0.000 description 1
- 244000081841 Malus domestica Species 0.000 description 1
- 244000113938 Malvastrum americanum Species 0.000 description 1
- 241000555300 Mamestra Species 0.000 description 1
- 241000555303 Mamestra brassicae Species 0.000 description 1
- 241000732113 Mamestra configurata Species 0.000 description 1
- 239000005803 Mandestrobin Substances 0.000 description 1
- 239000005804 Mandipropamid Substances 0.000 description 1
- 241000256010 Manduca Species 0.000 description 1
- 241000369513 Manduca quinquemaculata Species 0.000 description 1
- 241000255908 Manduca sexta Species 0.000 description 1
- 241001354481 Mansonia <mosquito genus> Species 0.000 description 1
- 241000114268 Marchalina hellenica Species 0.000 description 1
- 241000273029 Marginitermes Species 0.000 description 1
- 241000934359 Marmara Species 0.000 description 1
- 241001232130 Maruca testulalis Species 0.000 description 1
- 241000721710 Mastotermes Species 0.000 description 1
- 241000721708 Mastotermes darwiniensis Species 0.000 description 1
- 241001533428 Mayetiola Species 0.000 description 1
- 241001422926 Mayetiola hordei Species 0.000 description 1
- 241001223554 Megacopta cribraria Species 0.000 description 1
- 241001591816 Megalopyge Species 0.000 description 1
- 241001357070 Megaplatypus Species 0.000 description 1
- 241000171293 Megoura viciae Species 0.000 description 1
- 241000726778 Melanaphis Species 0.000 description 1
- 241001179564 Melanaphis sacchari Species 0.000 description 1
- 241001367645 Melanchra picta Species 0.000 description 1
- 229940127408 Melanin Synthesis Inhibitors Drugs 0.000 description 1
- 241000590505 Melanitis leda Species 0.000 description 1
- 206010027146 Melanoderma Diseases 0.000 description 1
- 241001415013 Melanoplus Species 0.000 description 1
- 241001478935 Melanoplus bivittatus Species 0.000 description 1
- 241001478965 Melanoplus femurrubrum Species 0.000 description 1
- 241001582344 Melanoplus mexicanus Species 0.000 description 1
- 241000922538 Melanoplus sanguinipes Species 0.000 description 1
- 241001051646 Melanoplus spretus Species 0.000 description 1
- 241001394950 Melanotus communis (Gyllenhal, 1817) Species 0.000 description 1
- 241000766511 Meligethes Species 0.000 description 1
- 241001143352 Meloidogyne Species 0.000 description 1
- 241000243787 Meloidogyne hapla Species 0.000 description 1
- 241000243786 Meloidogyne incognita Species 0.000 description 1
- 241000254071 Melolontha Species 0.000 description 1
- 241000828959 Melolontha hippocastani Species 0.000 description 1
- 241000254099 Melolontha melolontha Species 0.000 description 1
- 241000292449 Menacanthus stramineus Species 0.000 description 1
- 241000035435 Menopon gallinae Species 0.000 description 1
- 239000005805 Mepanipyrim Substances 0.000 description 1
- 241001540470 Mesocriconema Species 0.000 description 1
- 241001540472 Mesocriconema xenoplax Species 0.000 description 1
- 240000002624 Mespilus germanica Species 0.000 description 1
- 239000005808 Metalaxyl-M Substances 0.000 description 1
- 239000002169 Metam Substances 0.000 description 1
- 241001212755 Metamasius hemipterus Species 0.000 description 1
- 239000005951 Methiocarb Substances 0.000 description 1
- 239000005917 Methoxyfenozide Substances 0.000 description 1
- 102100021299 Methyl-CpG-binding domain protein 2 Human genes 0.000 description 1
- 241000168713 Metopolophium dirhodum Species 0.000 description 1
- LTMQQEMGRMBUSL-UHFFFAOYSA-N Metoxadiazone Chemical compound O=C1OC(OC)=NN1C1=CC=CC=C1OC LTMQQEMGRMBUSL-UHFFFAOYSA-N 0.000 description 1
- 241000665748 Microcephalothrips abdominalis Species 0.000 description 1
- 241001497122 Migdolus Species 0.000 description 1
- 241001497125 Migdolus fryanus Species 0.000 description 1
- 239000005918 Milbemectin Substances 0.000 description 1
- 102000013379 Mitochondrial Proton-Translocating ATPases Human genes 0.000 description 1
- 108010026155 Mitochondrial Proton-Translocating ATPases Proteins 0.000 description 1
- 241001653186 Mocis Species 0.000 description 1
- 241000108255 Modicella Species 0.000 description 1
- 241000237852 Mollusca Species 0.000 description 1
- 241001094463 Monellia Species 0.000 description 1
- 241001094800 Monelliopsis Species 0.000 description 1
- 241001442208 Monochamus Species 0.000 description 1
- 241000363274 Monochroa fragariae Species 0.000 description 1
- 241000952627 Monomorium pharaonis Species 0.000 description 1
- 241001343875 Moraea autumnalis Species 0.000 description 1
- 241001343744 Moraea miniata Species 0.000 description 1
- 241000032189 Morychus aeneus Species 0.000 description 1
- 241001101705 Murgantia Species 0.000 description 1
- 241000257229 Musca <genus> Species 0.000 description 1
- 244000082079 Muscari comosum Species 0.000 description 1
- 241000581981 Muscina stabulans Species 0.000 description 1
- 239000005811 Myclobutanil Substances 0.000 description 1
- 241001477928 Mythimna Species 0.000 description 1
- 241000409991 Mythimna separata Species 0.000 description 1
- 241001594248 Mythimna sequax Species 0.000 description 1
- 241000721623 Myzus Species 0.000 description 1
- 241000332345 Myzus cerasi Species 0.000 description 1
- 241000721621 Myzus persicae Species 0.000 description 1
- 241001140180 Myzus persicae nicotianae Species 0.000 description 1
- 241000332347 Myzus varians Species 0.000 description 1
- XSYIIGPTLDKNNH-UHFFFAOYSA-N N'-[5-bromo-2-methyl-6-(1-phenylethoxy)pyridin-3-yl]-N-ethyl-N-methylmethanimidamide Chemical compound BrC=1C=C(C(=NC=1OC(C)C1=CC=CC=C1)C)N=CN(C)CC XSYIIGPTLDKNNH-UHFFFAOYSA-N 0.000 description 1
- IQYZVFIDTOVZTN-UHFFFAOYSA-N N,2-dimethyl-N-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)butanethioamide Chemical compound CCC(C)C(=S)N(C)c1sc(nc1C)-c1cccnc1 IQYZVFIDTOVZTN-UHFFFAOYSA-N 0.000 description 1
- XMDNVMZGIIOPPG-UHFFFAOYSA-N N,5-dimethyl-1-(3-methylbutan-2-yl)-N-pyridazin-4-ylpyrazole-4-carboxamide Chemical compound CC(C(C)C)N1N=CC(=C1C)C(=O)N(C1=CN=NC=C1)C XMDNVMZGIIOPPG-UHFFFAOYSA-N 0.000 description 1
- DTHUVVADVUNYKW-UHFFFAOYSA-N N,5-dimethyl-N-pyridazin-4-yl-1-(1,1,1-trifluoropropan-2-yl)pyrazole-4-carboxamide Chemical compound CN(C(=O)C=1C=NN(C=1C)C(C(F)(F)F)C)C1=CN=NC=C1 DTHUVVADVUNYKW-UHFFFAOYSA-N 0.000 description 1
- IUOKJNROJISWRO-UHFFFAOYSA-N N-(2-cyano-3-methylbutan-2-yl)-2-(2,4-dichlorophenoxy)propanamide Chemical compound CC(C)C(C)(C#N)NC(=O)C(C)OC1=CC=C(Cl)C=C1Cl IUOKJNROJISWRO-UHFFFAOYSA-N 0.000 description 1
- PWBNQNHSOYLMMZ-UHFFFAOYSA-N N-(4-chloro-2-pyridin-3-yl-1,3-thiazol-5-yl)-N-ethyl-2-methylbutanethioamide Chemical compound CCC(C)C(=S)N(CC)c1sc(nc1Cl)-c1cccnc1 PWBNQNHSOYLMMZ-UHFFFAOYSA-N 0.000 description 1
- CKHSZGJSVMRZON-UHFFFAOYSA-N N-(4-chloro-2-pyridin-3-yl-1,3-thiazol-5-yl)-N-ethylbutanethioamide Chemical compound CCCC(=S)N(CC)c1sc(nc1Cl)-c1cccnc1 CKHSZGJSVMRZON-UHFFFAOYSA-N 0.000 description 1
- WGRLZWCRVKXSJW-UHFFFAOYSA-N N-(4-chloro-2-pyridin-3-yl-1,3-thiazol-5-yl)-N-methylbutanethioamide Chemical compound CCCC(=S)N(C)c1sc(nc1Cl)-c1cccnc1 WGRLZWCRVKXSJW-UHFFFAOYSA-N 0.000 description 1
- XFOXDUJCOHBXRC-UHFFFAOYSA-N N-Ethyl-N-methyl-4-(trifluoromethyl)-2-(3,4-dimethoxyphenyl)benzamide Chemical compound CCN(C)C(=O)C1=CC=C(C(F)(F)F)C=C1C1=CC=C(OC)C(OC)=C1 XFOXDUJCOHBXRC-UHFFFAOYSA-N 0.000 description 1
- QNMAHHJXYAMBNO-UHFFFAOYSA-N N-[2-bromo-4-(1,1,1,2,3,3,4,4,4-nonafluorobutan-2-yl)-6-(trifluoromethyl)phenyl]-2-fluoro-3-(phenacylamino)benzamide Chemical compound Fc1c(NCC(=O)c2ccccc2)cccc1C(=O)Nc1c(Br)cc(cc1C(F)(F)F)C(F)(C(F)(F)F)C(F)(F)C(F)(F)F QNMAHHJXYAMBNO-UHFFFAOYSA-N 0.000 description 1
- CCCGEKHKTPTUHJ-UHFFFAOYSA-N N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=CC2=C1C1CCC2C1=C(Cl)Cl CCCGEKHKTPTUHJ-UHFFFAOYSA-N 0.000 description 1
- NQRFDNJEBWAUBL-UHFFFAOYSA-N N-[cyano(2-thienyl)methyl]-4-ethyl-2-(ethylamino)-1,3-thiazole-5-carboxamide Chemical compound S1C(NCC)=NC(CC)=C1C(=O)NC(C#N)C1=CC=CS1 NQRFDNJEBWAUBL-UHFFFAOYSA-N 0.000 description 1
- ZQPIADKUNVJRFW-UHFFFAOYSA-N N-ethyl-1-(3-fluorobutan-2-yl)-5-methyl-N-pyridazin-4-ylpyrazole-4-carboxamide Chemical compound C(C)N(C(=O)C=1C=NN(C=1C)C(C(C)F)C)C1=CN=NC=C1 ZQPIADKUNVJRFW-UHFFFAOYSA-N 0.000 description 1
- JWTUIKPBGVTUGJ-UHFFFAOYSA-N N-ethyl-2-methyl-N-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)butanethioamide Chemical compound CCC(C)C(=S)N(CC)c1sc(nc1C)-c1cccnc1 JWTUIKPBGVTUGJ-UHFFFAOYSA-N 0.000 description 1
- NTYJVFXPSJKCPV-UHFFFAOYSA-N N-ethyl-N-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)butanethioamide Chemical compound CCCC(=S)N(CC)c1sc(nc1C)-c1cccnc1 NTYJVFXPSJKCPV-UHFFFAOYSA-N 0.000 description 1
- VZIWNVBCQBUIPR-UHFFFAOYSA-N N-methyl-N-(4-methyl-2-pyridin-3-yl-1,3-thiazol-5-yl)butanethioamide Chemical compound CCCC(=S)N(C)c1sc(nc1C)-c1cccnc1 VZIWNVBCQBUIPR-UHFFFAOYSA-N 0.000 description 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 description 1
- 150000001204 N-oxides Chemical class 0.000 description 1
- 241000201433 Nacobbus Species 0.000 description 1
- 241000583618 Nacobbus bolivianus Species 0.000 description 1
- 241000379990 Nakataea oryzae Species 0.000 description 1
- 241000595949 Narceus Species 0.000 description 1
- 241000133263 Nasonovia ribisnigri Species 0.000 description 1
- 241000196499 Naupactus xanthographus Species 0.000 description 1
- 241000540364 Nemapogon cloacella Species 0.000 description 1
- 241001137882 Nematodirus Species 0.000 description 1
- 241001125804 Neocapritermes Species 0.000 description 1
- 241000400685 Neoleucinodes elegantalis Species 0.000 description 1
- 241000192234 Neomegalotomus Species 0.000 description 1
- 241000204052 Neotermes Species 0.000 description 1
- 241001088173 Neotoxoptera formosana Species 0.000 description 1
- 241000359016 Nephotettix Species 0.000 description 1
- 241001551868 Nephotettix malayanus Species 0.000 description 1
- 241000615716 Nephotettix nigropictus Species 0.000 description 1
- 241001369136 Nepytia Species 0.000 description 1
- 101100172173 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) hcr-1 gene Proteins 0.000 description 1
- 241001671714 Nezara Species 0.000 description 1
- 241001671709 Nezara viridula Species 0.000 description 1
- 241001556089 Nilaparvata lugens Species 0.000 description 1
- 241001385056 Niptus hololeucus Species 0.000 description 1
- VJAWBEFMCIINFU-UHFFFAOYSA-N Nitrothal-isopropyl Chemical compound CC(C)OC(=O)C1=CC(C(=O)OC(C)C)=CC([N+]([O-])=O)=C1 VJAWBEFMCIINFU-UHFFFAOYSA-N 0.000 description 1
- 241000256259 Noctuidae Species 0.000 description 1
- 241000916006 Nomadacris septemfasciata Species 0.000 description 1
- 241001036422 Nosopsyllus fasciatus Species 0.000 description 1
- 241001338708 Nymphula Species 0.000 description 1
- 241000660989 Nysius Species 0.000 description 1
- DWWJBKSSHBITBL-UHFFFAOYSA-N O=C(NC1CC1)c1cccc2nn(cc12)-c1cccnc1 Chemical compound O=C(NC1CC1)c1cccc2nn(cc12)-c1cccnc1 DWWJBKSSHBITBL-UHFFFAOYSA-N 0.000 description 1
- DGGNOYAGSYOVOG-UHFFFAOYSA-N O=C(NC1CCCCC1)c1cccc2nn(cc12)-c1cccnc1 Chemical compound O=C(NC1CCCCC1)c1cccc2nn(cc12)-c1cccnc1 DGGNOYAGSYOVOG-UHFFFAOYSA-N 0.000 description 1
- IJZJNPCMROOUFU-UHFFFAOYSA-N O=C(NCC1CCCO1)c1ccc2nn(cc2c1)-c1cccnc1 Chemical compound O=C(NCC1CCCO1)c1ccc2nn(cc2c1)-c1cccnc1 IJZJNPCMROOUFU-UHFFFAOYSA-N 0.000 description 1
- FQZYJHRPNOHECR-UHFFFAOYSA-N O=C(NCc1ncccn1)c1ccc2nn(cc2c1)-c1cccnc1 Chemical compound O=C(NCc1ncccn1)c1ccc2nn(cc2c1)-c1cccnc1 FQZYJHRPNOHECR-UHFFFAOYSA-N 0.000 description 1
- 241000866537 Odontotermes Species 0.000 description 1
- 241001102020 Oebalus Species 0.000 description 1
- 241001446843 Oebalus pugnax Species 0.000 description 1
- 241000122522 Oedaleus senegalensis Species 0.000 description 1
- 241001397429 Oemona hirta Species 0.000 description 1
- 241000510960 Oesophagostomum Species 0.000 description 1
- 241001157094 Oiketicus Species 0.000 description 1
- 241000207836 Olea <angiosperm> Species 0.000 description 1
- 241000851137 Oligonychus perseae Species 0.000 description 1
- 241001000387 Omphisa anastomosalis Species 0.000 description 1
- 241000243985 Onchocerca volvulus Species 0.000 description 1
- 241000565675 Oncomelania Species 0.000 description 1
- 241000777573 Oncometopia Species 0.000 description 1
- 241000384103 Oniscus asellus Species 0.000 description 1
- 241000963706 Onychiurus Species 0.000 description 1
- 241000963703 Onychiurus armatus Species 0.000 description 1
- 241000242716 Opisthorchis Species 0.000 description 1
- 241001483209 Opomyza florum Species 0.000 description 1
- 241001465803 Orgyia pseudotsugata Species 0.000 description 1
- 241000238887 Ornithodoros Species 0.000 description 1
- 241000907873 Ornithodoros hermsi Species 0.000 description 1
- 241000238890 Ornithodoros moubata Species 0.000 description 1
- 241001481099 Ornithodoros turicata Species 0.000 description 1
- 241000176318 Ornithonyssus bacoti Species 0.000 description 1
- 241001465818 Orseolia oryzae Species 0.000 description 1
- 241001578834 Orthaga thyrisalis Species 0.000 description 1
- 241001446191 Orthezia Species 0.000 description 1
- 241000238814 Orthoptera Species 0.000 description 1
- 241001250072 Oryctes rhinoceros Species 0.000 description 1
- 241000131101 Oryzaephilus surinamensis Species 0.000 description 1
- 241001157806 Oscinella Species 0.000 description 1
- 241000975417 Oscinella frit Species 0.000 description 1
- 241000243795 Ostertagia Species 0.000 description 1
- 241001147397 Ostrinia Species 0.000 description 1
- 241000346285 Ostrinia furnacalis Species 0.000 description 1
- 241001147398 Ostrinia nubilalis Species 0.000 description 1
- 241001480756 Otobius megnini Species 0.000 description 1
- 241000604373 Ovatus Species 0.000 description 1
- 241000283903 Ovis aries Species 0.000 description 1
- 239000005950 Oxamyl Substances 0.000 description 1
- 239000005812 Oxathiapiprolin Substances 0.000 description 1
- KYGZCKSPAKDVKC-UHFFFAOYSA-N Oxolinic acid Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC2=C1OCO2 KYGZCKSPAKDVKC-UHFFFAOYSA-N 0.000 description 1
- 241001374759 Pachycondyla chinensis Species 0.000 description 1
- 241001585671 Paleacrita vernata Species 0.000 description 1
- 241001510262 Panchlora nivea Species 0.000 description 1
- 241000486438 Panolis flammea Species 0.000 description 1
- 241000488585 Panonychus Species 0.000 description 1
- 241000488583 Panonychus ulmi Species 0.000 description 1
- 241001657689 Papaipema nebris Species 0.000 description 1
- 241001480233 Paragonimus Species 0.000 description 1
- 241000497111 Paralobesia viteana Species 0.000 description 1
- 241001130173 Paralongidorus maximus Species 0.000 description 1
- 241000885974 Paranthrene Species 0.000 description 1
- 241000459456 Parapediasia teterrellus Species 0.000 description 1
- 241000188667 Parasteatoda tepidariorum Species 0.000 description 1
- 241000051771 Paratrechina longicornis Species 0.000 description 1
- 241001220391 Paratrichodorus Species 0.000 description 1
- 244000309691 Paratylenchus curvitatus Species 0.000 description 1
- 241001622647 Parnara Species 0.000 description 1
- 241001450659 Parthenolecanium Species 0.000 description 1
- 241000094111 Parthenolecanium persicae Species 0.000 description 1
- 244000290719 Paspalidium geminatum Species 0.000 description 1
- 241001580103 Paysandisia archon Species 0.000 description 1
- 241000721452 Pectinophora Species 0.000 description 1
- 241000721451 Pectinophora gossypiella Species 0.000 description 1
- 241000517325 Pediculus Species 0.000 description 1
- 241000517307 Pediculus humanus Species 0.000 description 1
- 241000562493 Pegomya Species 0.000 description 1
- 241000721454 Pemphigus Species 0.000 description 1
- 241000609952 Pemphigus bursarius Species 0.000 description 1
- 241000228555 Pemphigus populivenae Species 0.000 description 1
- 239000005813 Penconazole Substances 0.000 description 1
- 239000005814 Pencycuron Substances 0.000 description 1
- 241001177887 Penthaleidae Species 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- 241000256682 Peregrinus maidis Species 0.000 description 1
- 241001013804 Peridroma saucia Species 0.000 description 1
- 241000238661 Periplaneta Species 0.000 description 1
- 241001510004 Periplaneta australasiae Species 0.000 description 1
- 241001510001 Periplaneta brunnea Species 0.000 description 1
- 241001253326 Perkinsiella saccharicida Species 0.000 description 1
- 241000218196 Persea Species 0.000 description 1
- 235000008673 Persea americana Nutrition 0.000 description 1
- 241000316608 Petrobia latens Species 0.000 description 1
- 241000910062 Pezothrips kellyanus Species 0.000 description 1
- 241001608568 Phaedon Species 0.000 description 1
- 241001608567 Phaedon cochleariae Species 0.000 description 1
- 244000309618 Phakopsora gossypii Species 0.000 description 1
- 241001579681 Phalera bucephala Species 0.000 description 1
- 241001406390 Pheidole Species 0.000 description 1
- 241001564690 Pheidole dispar Species 0.000 description 1
- 241000868180 Pheidole megacephala Species 0.000 description 1
- 241001058119 Phenacoccus Species 0.000 description 1
- 241000549765 Phenacoccus aceris Species 0.000 description 1
- 241000358502 Phlebotomus argentipes Species 0.000 description 1
- 241000916811 Phloeomyzus Species 0.000 description 1
- 244000089933 Phoebe grandis Species 0.000 description 1
- 241001202231 Phoracantha recurva Species 0.000 description 1
- 241001401861 Phorodon humuli Species 0.000 description 1
- 239000005921 Phosmet Substances 0.000 description 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 description 1
- 241001190492 Phryganidia californica Species 0.000 description 1
- 241001674048 Phthiraptera Species 0.000 description 1
- 241001439020 Phthorimaea Species 0.000 description 1
- 241001439019 Phthorimaea operculella Species 0.000 description 1
- 241001168626 Phyllobius pyri Species 0.000 description 1
- 241001525654 Phyllocnistis citrella Species 0.000 description 1
- 241000497192 Phyllocoptruta oleivora Species 0.000 description 1
- 241000720470 Phyllonorycter Species 0.000 description 1
- 241001517955 Phyllonorycter blancardella Species 0.000 description 1
- 241000633354 Phyllonorycter crataegella Species 0.000 description 1
- 241000633168 Phyllonorycter issikii Species 0.000 description 1
- 241001190782 Phyllonorycter ringoniella Species 0.000 description 1
- 241001640279 Phyllophaga Species 0.000 description 1
- 241000275067 Phyllotreta Species 0.000 description 1
- 241000517946 Phyllotreta nemorum Species 0.000 description 1
- 241000426337 Phyllotreta vittula Species 0.000 description 1
- 241001516577 Phylloxera Species 0.000 description 1
- 241000645329 Phytomyza gymnostoma Species 0.000 description 1
- 241001396980 Phytonemus pallidus Species 0.000 description 1
- 241000255972 Pieris <butterfly> Species 0.000 description 1
- 241001313099 Pieris napi Species 0.000 description 1
- 241000907661 Pieris rapae Species 0.000 description 1
- 241000690748 Piesma Species 0.000 description 1
- 241000940371 Piezodorus Species 0.000 description 1
- 241000668987 Pinnaspis Species 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 240000003889 Piper guineense Species 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- 239000005923 Pirimicarb Substances 0.000 description 1
- 239000005924 Pirimiphos-methyl Substances 0.000 description 1
- 240000006711 Pistacia vera Species 0.000 description 1
- 241000193804 Planococcus <bacterium> Species 0.000 description 1
- 241001058004 Planococcus ficus Species 0.000 description 1
- 241001608845 Platynota Species 0.000 description 1
- 241001608848 Platynota idaeusalis Species 0.000 description 1
- 241001456328 Platynota stultana Species 0.000 description 1
- 241000988169 Plebejus argus Species 0.000 description 1
- 241000595629 Plodia interpunctella Species 0.000 description 1
- 241000723784 Plum pox virus Species 0.000 description 1
- 241001363501 Plusia Species 0.000 description 1
- 241001289556 Pogonomyrmex Species 0.000 description 1
- 241001289568 Pogonomyrmex barbatus Species 0.000 description 1
- 229930182764 Polyoxin Natural products 0.000 description 1
- 241000952063 Polyphagotarsonemus latus Species 0.000 description 1
- 241001251227 Pomacea Species 0.000 description 1
- 241000143946 Pontia Species 0.000 description 1
- 241000254101 Popillia japonica Species 0.000 description 1
- 241001600128 Populus tremula x Populus alba Species 0.000 description 1
- 241000908127 Porcellio scaber Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 241000193943 Pratylenchus Species 0.000 description 1
- 241000193978 Pratylenchus brachyurus Species 0.000 description 1
- 241000710336 Pratylenchus goodeyi Species 0.000 description 1
- 241000193960 Pratylenchus minyus Species 0.000 description 1
- 241000193940 Pratylenchus penetrans Species 0.000 description 1
- 241001201614 Prays Species 0.000 description 1
- 241000051775 Prenolepis Species 0.000 description 1
- 241000181848 Procornitermes Species 0.000 description 1
- 239000005821 Propamocarb Substances 0.000 description 1
- 239000005822 Propiconazole Substances 0.000 description 1
- 239000005823 Propineb Substances 0.000 description 1
- 241000994732 Prosapia bicincta Species 0.000 description 1
- 241000797772 Prosimulium mixtum Species 0.000 description 1
- 241001459657 Prostephanus Species 0.000 description 1
- 241000590524 Protaphis middletonii Species 0.000 description 1
- 229940123573 Protein synthesis inhibitor Drugs 0.000 description 1
- 241001582348 Proxenus Species 0.000 description 1
- 241001657916 Proxenus mindara Species 0.000 description 1
- 241001290151 Prunus avium subsp. avium Species 0.000 description 1
- 235000005805 Prunus cerasus Nutrition 0.000 description 1
- 244000141353 Prunus domestica Species 0.000 description 1
- 235000011435 Prunus domestica Nutrition 0.000 description 1
- 240000005809 Prunus persica Species 0.000 description 1
- 235000006029 Prunus persica var nucipersica Nutrition 0.000 description 1
- 235000006040 Prunus persica var persica Nutrition 0.000 description 1
- 244000017714 Prunus persica var. nucipersica Species 0.000 description 1
- 241001610009 Prunus texana Species 0.000 description 1
- 241000027515 Psacothea hilaris Species 0.000 description 1
- 241000914631 Psallus Species 0.000 description 1
- 241001274600 Pseudacysta Species 0.000 description 1
- 241000668989 Pseudaulacaspis Species 0.000 description 1
- 241000722234 Pseudococcus Species 0.000 description 1
- 241000596535 Pseudococcus comstocki Species 0.000 description 1
- 241001646398 Pseudomonas chlororaphis Species 0.000 description 1
- 241001484749 Pseudomonas helleri Species 0.000 description 1
- 241001638575 Pseudomyrmex gracilis Species 0.000 description 1
- 241000060092 Psorophora columbiae Species 0.000 description 1
- 241000991597 Psorophora discolor Species 0.000 description 1
- 241001649229 Psoroptes Species 0.000 description 1
- 241001649230 Psoroptes ovis Species 0.000 description 1
- 241001160824 Psylliodes Species 0.000 description 1
- 241001454908 Pteromalus Species 0.000 description 1
- 241000517304 Pthirus pubis Species 0.000 description 1
- 241001105129 Ptinus Species 0.000 description 1
- 241000718000 Pulex irritans Species 0.000 description 1
- 241000382353 Pupa Species 0.000 description 1
- 240000008377 Puya chilensis Species 0.000 description 1
- 241001510228 Pycnoscelus surinamensis Species 0.000 description 1
- 241000238709 Pyemotes tritici Species 0.000 description 1
- 241000238704 Pyemotidae Species 0.000 description 1
- 241001590455 Pyrausta Species 0.000 description 1
- VQXSOUPNOZTNAI-UHFFFAOYSA-N Pyrethrin I Natural products CC(=CC1CC1C(=O)OC2CC(=O)C(=C2C)CC=C/C=C)C VQXSOUPNOZTNAI-UHFFFAOYSA-N 0.000 description 1
- 239000005663 Pyridaben Substances 0.000 description 1
- 239000005926 Pyridalyl Substances 0.000 description 1
- 241000932787 Pyrilla Species 0.000 description 1
- 239000005829 Pyriofenone Substances 0.000 description 1
- MWMQNVGAHVXSPE-UHFFFAOYSA-N Pyriprole Chemical compound ClC=1C=C(C(F)(F)F)C=C(Cl)C=1N1N=C(C#N)C(SC(F)F)=C1NCC1=CC=CC=N1 MWMQNVGAHVXSPE-UHFFFAOYSA-N 0.000 description 1
- 239000005927 Pyriproxyfen Substances 0.000 description 1
- 241000220324 Pyrus Species 0.000 description 1
- 244000184734 Pyrus japonica Species 0.000 description 1
- 241000944747 Quesada gigas Species 0.000 description 1
- 239000005831 Quinoxyfen Substances 0.000 description 1
- 241001456339 Rachiplusia nu Species 0.000 description 1
- 241000201377 Radopholus Species 0.000 description 1
- 241001019266 Raoiella indica Species 0.000 description 1
- 241000549289 Rastrococcus Species 0.000 description 1
- 241000351478 Reduvius Species 0.000 description 1
- 241001509970 Reticulitermes <genus> Species 0.000 description 1
- 241001509967 Reticulitermes flavipes Species 0.000 description 1
- 241000010212 Reticulitermes grassei Species 0.000 description 1
- 241001152954 Reticulitermes hesperus Species 0.000 description 1
- 241000590363 Reticulitermes lucifugus Species 0.000 description 1
- 241000590379 Reticulitermes santonensis Species 0.000 description 1
- 241000866500 Reticulitermes speratus Species 0.000 description 1
- 241001105413 Reticulitermes tibialis Species 0.000 description 1
- 241000577913 Reticulitermes virginicus Species 0.000 description 1
- 241001136852 Rhagoletis Species 0.000 description 1
- 241000157279 Rhagoletis cerasi Species 0.000 description 1
- 241000156912 Rhagoletis indifferens Species 0.000 description 1
- 241001465970 Rhagoletis mendax Species 0.000 description 1
- 241001136903 Rhagoletis pomonella Species 0.000 description 1
- 241001480837 Rhipicephalus annulatus Species 0.000 description 1
- 241001481704 Rhipicephalus appendiculatus Species 0.000 description 1
- 241000864246 Rhipicephalus decoloratus Species 0.000 description 1
- 241000864202 Rhipicephalus evertsi Species 0.000 description 1
- 241000238680 Rhipicephalus microplus Species 0.000 description 1
- 241001481696 Rhipicephalus sanguineus Species 0.000 description 1
- 241000298314 Rhipiphorothrips cruentatus Species 0.000 description 1
- 241001058123 Rhizoecus Species 0.000 description 1
- 241001617044 Rhizoglyphus Species 0.000 description 1
- ISRUGXGCCGIOQO-UHFFFAOYSA-N Rhoden Chemical compound CNC(=O)OC1=CC=CC=C1OC(C)C ISRUGXGCCGIOQO-UHFFFAOYSA-N 0.000 description 1
- 241000722251 Rhodnius Species 0.000 description 1
- 240000008199 Rhododendron molle Species 0.000 description 1
- 241000125162 Rhopalosiphum Species 0.000 description 1
- 241000426569 Rhopalosiphum insertum Species 0.000 description 1
- 241000167882 Rhopalosiphum maidis Species 0.000 description 1
- 241000125167 Rhopalosiphum padi Species 0.000 description 1
- 241001575051 Rhyacionia Species 0.000 description 1
- 241000344244 Rhynchophorus Species 0.000 description 1
- 241001078693 Rhynchophorus ferrugineus Species 0.000 description 1
- 241000344245 Rhynchophorus palmarum Species 0.000 description 1
- 241001212820 Rhynchophorus phoenicis Species 0.000 description 1
- 241001653790 Rhynchophorus vulneratus Species 0.000 description 1
- 241001510236 Rhyparobia maderae Species 0.000 description 1
- 241000752065 Rhyzobius Species 0.000 description 1
- 241000318997 Rhyzopertha dominica Species 0.000 description 1
- 235000002357 Ribes grossularia Nutrition 0.000 description 1
- 108010039491 Ricin Proteins 0.000 description 1
- 235000004443 Ricinus communis Nutrition 0.000 description 1
- 241001136823 Rivellia quadrifasciata Species 0.000 description 1
- 241000855013 Rotylenchus Species 0.000 description 1
- 241001132771 Rotylenchus buxophilus Species 0.000 description 1
- 241001092459 Rubus Species 0.000 description 1
- 240000007651 Rubus glaucus Species 0.000 description 1
- 241001274937 Rubus robustus Species 0.000 description 1
- 241000004261 Sabulodes Species 0.000 description 1
- 241000914334 Sahlbergella singularis Species 0.000 description 1
- 241001450655 Saissetia Species 0.000 description 1
- 241001161341 Saperda Species 0.000 description 1
- 241001402072 Sappaphis Species 0.000 description 1
- 241001402070 Sappaphis piri Species 0.000 description 1
- 241000257190 Sarcophaga <genus> Species 0.000 description 1
- 241000375532 Sarcophaga haemorrhoidalis Species 0.000 description 1
- 241000509416 Sarcoptes Species 0.000 description 1
- 241000509418 Sarcoptidae Species 0.000 description 1
- 241001243781 Scapteriscus Species 0.000 description 1
- 241000726726 Scaptocoris Species 0.000 description 1
- 241000254026 Schistocerca Species 0.000 description 1
- 241000253973 Schistocerca gregaria Species 0.000 description 1
- 241000722027 Schizaphis graminum Species 0.000 description 1
- 241001351292 Schizura concinna Species 0.000 description 1
- 241001579307 Schoenobius Species 0.000 description 1
- 241001340905 Schreckensteinia festaliella Species 0.000 description 1
- 241001249127 Scirpophaga Species 0.000 description 1
- 241001249129 Scirpophaga incertulas Species 0.000 description 1
- 241000098281 Scirpophaga innotata Species 0.000 description 1
- 241000365764 Scirtothrips dorsalis Species 0.000 description 1
- 241001615652 Scirtothrips perseae Species 0.000 description 1
- 241001476700 Scolytus schevyrewi Species 0.000 description 1
- 241001347878 Scrobipalpula Species 0.000 description 1
- 241000332476 Scutellonema Species 0.000 description 1
- 241000332477 Scutellonema bradys Species 0.000 description 1
- 241001157779 Scutigera Species 0.000 description 1
- 241001157780 Scutigera coleoptrata Species 0.000 description 1
- 241001313237 Scutigerella immaculata Species 0.000 description 1
- 241001212819 Scyphophorus acupunctatus Species 0.000 description 1
- 241001423858 Scytonematopsis Species 0.000 description 1
- 241000669326 Selenaspidus articulatus Species 0.000 description 1
- 241000931987 Sesamia Species 0.000 description 1
- 241000563489 Sesamia inferens Species 0.000 description 1
- CSPPKDPQLUUTND-NBVRZTHBSA-N Sethoxydim Chemical compound CCO\N=C(/CCC)C1=C(O)CC(CC(C)SCC)CC1=O CSPPKDPQLUUTND-NBVRZTHBSA-N 0.000 description 1
- 239000005835 Silthiofam Substances 0.000 description 1
- 241000256106 Simulium vittatum Species 0.000 description 1
- 241001041011 Sirex cyaneus Species 0.000 description 1
- 241000068648 Sitodiplosis mosellana Species 0.000 description 1
- 241001168723 Sitona lineatus Species 0.000 description 1
- 241000254181 Sitophilus Species 0.000 description 1
- 241000254154 Sitophilus zeamais Species 0.000 description 1
- 241000753145 Sitotroga cerealella Species 0.000 description 1
- 241000336929 Sogata Species 0.000 description 1
- 241000176086 Sogatella furcifera Species 0.000 description 1
- 241000044147 Solenopotes capillatus Species 0.000 description 1
- 241001492664 Solenopsis <angiosperm> Species 0.000 description 1
- 241000958652 Solenopsis molesta Species 0.000 description 1
- 241001415041 Solenopsis richteri Species 0.000 description 1
- 244000185830 Sorbus americana Species 0.000 description 1
- 241000950793 Sorbus vexans Species 0.000 description 1
- 235000015505 Sorghum bicolor subsp. bicolor Nutrition 0.000 description 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- 241000277984 Sparganothis pilleriana Species 0.000 description 1
- 241000256676 Sphecius speciosus Species 0.000 description 1
- 241000532885 Sphenophorus Species 0.000 description 1
- 241000339283 Sphex Species 0.000 description 1
- 241001201846 Spilonota ocellana Species 0.000 description 1
- 235000009337 Spinacia oleracea Nutrition 0.000 description 1
- 244000300264 Spinacia oleracea Species 0.000 description 1
- 239000005837 Spiroxamine Substances 0.000 description 1
- 241000256247 Spodoptera exigua Species 0.000 description 1
- 241000985245 Spodoptera litura Species 0.000 description 1
- 244000107946 Spondias cytherea Species 0.000 description 1
- 240000003949 Sporobolus virginicus Species 0.000 description 1
- 241001177161 Stegobium paniceum Species 0.000 description 1
- 241000514831 Stemphylium botryosum Species 0.000 description 1
- 241000298312 Stenchaetothrips Species 0.000 description 1
- 241000349647 Steneotarsonemus spinki Species 0.000 description 1
- 241000283614 Stephanitis nashi Species 0.000 description 1
- 241001508985 Stephanitis pyrioides Species 0.000 description 1
- 241000693392 Stephanitis takeyai Species 0.000 description 1
- 241000950030 Sternechus Species 0.000 description 1
- 241000950032 Sternechus subsignatus Species 0.000 description 1
- 235000006092 Stevia rebaudiana Nutrition 0.000 description 1
- 241000022611 Stigmella Species 0.000 description 1
- 241000063073 Stomopteryx Species 0.000 description 1
- 241001494139 Stomoxys Species 0.000 description 1
- 241001494115 Stomoxys calcitrans Species 0.000 description 1
- 241000187181 Streptomyces scabiei Species 0.000 description 1
- 229930182692 Strobilurin Natural products 0.000 description 1
- 241000244174 Strongyloides Species 0.000 description 1
- 241000244177 Strongyloides stercoralis Species 0.000 description 1
- 241000430160 Strophomorphus Species 0.000 description 1
- 241001470115 Strymon bazochii Species 0.000 description 1
- 241001301282 Succinea Species 0.000 description 1
- 229940100389 Sulfonylurea Drugs 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005935 Sulfuryl fluoride Substances 0.000 description 1
- 241001649251 Supella Species 0.000 description 1
- 241000883295 Symphyla Species 0.000 description 1
- 241001528589 Synanthedon Species 0.000 description 1
- 241001528590 Synanthedon exitiosa Species 0.000 description 1
- 241000255626 Tabanus <genus> Species 0.000 description 1
- 241000255632 Tabanus atratus Species 0.000 description 1
- 241000244159 Taenia saginata Species 0.000 description 1
- 241000244157 Taenia solium Species 0.000 description 1
- 241000189577 Taeniothrips inconsequens Species 0.000 description 1
- 240000004460 Tanacetum coccineum Species 0.000 description 1
- 241000532791 Tanymecus Species 0.000 description 1
- 241001157792 Tapinoma Species 0.000 description 1
- 241001638573 Tapinoma melanocephalum Species 0.000 description 1
- 241000916145 Tarsonemidae Species 0.000 description 1
- 239000005937 Tebufenozide Substances 0.000 description 1
- 239000005658 Tebufenpyrad Substances 0.000 description 1
- 241000913276 Tecia solanivora Species 0.000 description 1
- 241000055289 Tectocoris diophthalmus Species 0.000 description 1
- 239000005938 Teflubenzuron Substances 0.000 description 1
- 241000254109 Tenebrio molitor Species 0.000 description 1
- 241000488607 Tenuipalpidae Species 0.000 description 1
- 241000897276 Termes Species 0.000 description 1
- 239000005840 Tetraconazole Substances 0.000 description 1
- 241000925469 Tetraleurodes perseae Species 0.000 description 1
- 241001415043 Tetramorium Species 0.000 description 1
- 241001638572 Tetramorium bicarinatum Species 0.000 description 1
- 241001374808 Tetramorium caespitum Species 0.000 description 1
- 241001454295 Tetranychidae Species 0.000 description 1
- 241001454294 Tetranychus Species 0.000 description 1
- 241000344246 Tetranychus cinnabarinus Species 0.000 description 1
- 241000488589 Tetranychus kanzawai Species 0.000 description 1
- 241000489254 Tetranychus takafujii Species 0.000 description 1
- 241001136977 Thaumatotibia Species 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 241000030538 Thecla Species 0.000 description 1
- 241000275431 Thecodiplosis japonensis Species 0.000 description 1
- 235000009470 Theobroma cacao Nutrition 0.000 description 1
- 244000299461 Theobroma cacao Species 0.000 description 1
- 241000842537 Theresimima Species 0.000 description 1
- 241000530360 Therioaphis Species 0.000 description 1
- 241000028626 Thermobia domestica Species 0.000 description 1
- 241000339373 Thrips palmi Species 0.000 description 1
- 241000797592 Thrips parvispinus Species 0.000 description 1
- 241000339374 Thrips tabaci Species 0.000 description 1
- 241001101718 Thyanta Species 0.000 description 1
- 241000341890 Thyanta accerra Species 0.000 description 1
- 241000051707 Thyanta perditor Species 0.000 description 1
- 241001419230 Thyrinteina Species 0.000 description 1
- 241000946381 Timon Species 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000130771 Tinea pellionella Species 0.000 description 1
- 241000333690 Tineola bisselliella Species 0.000 description 1
- 241001519477 Tinocallis Species 0.000 description 1
- 241001240492 Tipula oleracea Species 0.000 description 1
- 241000511627 Tipula paludosa Species 0.000 description 1
- 241001161507 Titanus Species 0.000 description 1
- 239000005845 Tolclofos-methyl Substances 0.000 description 1
- 241001432111 Tomaspis Species 0.000 description 1
- 241001271990 Tomicus piniperda Species 0.000 description 1
- 241001238452 Tortrix Species 0.000 description 1
- 241001238451 Tortrix viridana Species 0.000 description 1
- 241000271862 Toxoptera Species 0.000 description 1
- 108700019146 Transgenes Proteins 0.000 description 1
- 239000005846 Triadimenol Substances 0.000 description 1
- 241000018135 Trialeurodes Species 0.000 description 1
- 241000750338 Trialeurodes abutilonea Species 0.000 description 1
- 241000018137 Trialeurodes vaporariorum Species 0.000 description 1
- 241001414833 Triatoma Species 0.000 description 1
- 239000005847 Triazoxide Substances 0.000 description 1
- 241000254086 Tribolium <beetle> Species 0.000 description 1
- 241000254113 Tribolium castaneum Species 0.000 description 1
- 241000243776 Trichinella nativa Species 0.000 description 1
- 241000243779 Trichinella nelsoni Species 0.000 description 1
- 241000243777 Trichinella spiralis Species 0.000 description 1
- 241001259047 Trichodectes Species 0.000 description 1
- 241001259048 Trichodectes canis Species 0.000 description 1
- 241001220308 Trichodorus Species 0.000 description 1
- 241000355095 Trichodorus obtusus Species 0.000 description 1
- 241001220305 Trichodorus primitivus Species 0.000 description 1
- 241000539634 Trichophaga tapetzella Species 0.000 description 1
- 241000255985 Trichoplusia Species 0.000 description 1
- 241001489145 Trichuris trichiura Species 0.000 description 1
- 239000005942 Triflumuron Substances 0.000 description 1
- 240000006482 Trillium sessile Species 0.000 description 1
- 241001414858 Trioza Species 0.000 description 1
- 235000019714 Triticale Nutrition 0.000 description 1
- 240000000359 Triticum dicoccon Species 0.000 description 1
- 241000267823 Trogoderma Species 0.000 description 1
- 241001584775 Tunga penetrans Species 0.000 description 1
- 241001389010 Tuta Species 0.000 description 1
- 241001168740 Tychius Species 0.000 description 1
- 241000855019 Tylenchorhynchus Species 0.000 description 1
- 241001267618 Tylenchulus Species 0.000 description 1
- 241000841223 Typhlocyba Species 0.000 description 1
- 241000611866 Tyrophagus putrescentiae Species 0.000 description 1
- 241001201507 Udea Species 0.000 description 1
- 241000669245 Unaspis Species 0.000 description 1
- 241000368303 Unaspis citri Species 0.000 description 1
- 241001630065 Unaspis yanonensis Species 0.000 description 1
- 229930195482 Validamycin Natural products 0.000 description 1
- 239000005860 Valifenalate Substances 0.000 description 1
- 101710175177 Very-long-chain 3-oxoacyl-CoA reductase Proteins 0.000 description 1
- 241000256862 Vespa crabro Species 0.000 description 1
- 241000256838 Vespula Species 0.000 description 1
- 241001274787 Viteus Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 241000908414 Wasmannia auropunctata Species 0.000 description 1
- 241000609108 Wohlfahrtia Species 0.000 description 1
- 241000244002 Wuchereria Species 0.000 description 1
- CVQODEWAPZVVBU-UHFFFAOYSA-N XMC Chemical compound CNC(=O)OC1=CC(C)=CC(C)=C1 CVQODEWAPZVVBU-UHFFFAOYSA-N 0.000 description 1
- 235000013447 Xanthosoma atrovirens Nutrition 0.000 description 1
- 240000001781 Xanthosoma sagittifolium Species 0.000 description 1
- 241000353223 Xenopsylla cheopis Species 0.000 description 1
- 241000201423 Xiphinema Species 0.000 description 1
- 241000201421 Xiphinema index Species 0.000 description 1
- 241000256654 Xylocopa <genus> Species 0.000 description 1
- 241001604425 Xylotrechus Species 0.000 description 1
- 241001182329 Xylotrechus pyrrhoderus Species 0.000 description 1
- 241001466337 Yponomeuta Species 0.000 description 1
- 241001466330 Yponomeuta malinellus Species 0.000 description 1
- 241000064240 Yponomeuta padellus Species 0.000 description 1
- 241001035865 Zabrus Species 0.000 description 1
- 241000424289 Zabrus tenebrioides Species 0.000 description 1
- 101000923931 Zea mays Amino-acid acetyltransferase Proteins 0.000 description 1
- 241000495395 Zeiraphera canadensis Species 0.000 description 1
- 241001633596 Zephyranthes Species 0.000 description 1
- 241001136529 Zeugodacus cucurbitae Species 0.000 description 1
- 239000006011 Zinc phosphide Substances 0.000 description 1
- 239000005870 Ziram Substances 0.000 description 1
- 241000258237 Zootermopsis Species 0.000 description 1
- 241000258236 Zootermopsis angusticollis Species 0.000 description 1
- 241000964233 Zootermopsis nevadensis Species 0.000 description 1
- 239000005863 Zoxamide Substances 0.000 description 1
- 241001414985 Zygentoma Species 0.000 description 1
- GBAWQJNHVWMTLU-RQJHMYQMSA-N [(1R,5S)-7-chloro-6-bicyclo[3.2.0]hepta-2,6-dienyl] dimethyl phosphate Chemical compound C1=CC[C@@H]2C(OP(=O)(OC)OC)=C(Cl)[C@@H]21 GBAWQJNHVWMTLU-RQJHMYQMSA-N 0.000 description 1
- BJEDIYIAIQSQPZ-BWOOEJRBSA-N [(6S,7R,8R)-8-benzyl-3-[[4-methoxy-3-(propanoyloxymethoxy)pyridine-2-carbonyl]amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylpropanoate Chemical compound CC(C(=O)O[C@H]1[C@@H](OC(C(COC([C@@H]1CC1=CC=CC=C1)=O)NC(=O)C1=NC=CC(=C1OCOC(CC)=O)OC)=O)C)C BJEDIYIAIQSQPZ-BWOOEJRBSA-N 0.000 description 1
- MLGCATYQZVMGBG-JJOTWVSXSA-N [(6s,7r,8r)-8-benzyl-3-[(3-hydroxy-4-methoxypyridine-2-carbonyl)amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylpropanoate Chemical compound COC1=CC=NC(C(=O)NC2C(O[C@@H](C)[C@H](OC(=O)C(C)C)[C@@H](CC=3C=CC=CC=3)C(=O)OC2)=O)=C1O MLGCATYQZVMGBG-JJOTWVSXSA-N 0.000 description 1
- QQODLKZGRKWIFG-RUTXASTPSA-N [(R)-cyano-(4-fluoro-3-phenoxyphenyl)methyl] (1S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Chemical compound CC1(C)C(C=C(Cl)Cl)[C@@H]1C(=O)O[C@@H](C#N)C1=CC=C(F)C(OC=2C=CC=CC=2)=C1 QQODLKZGRKWIFG-RUTXASTPSA-N 0.000 description 1
- FZSVSABTBYGOQH-XFFZJAGNSA-N [(e)-(3,3-dimethyl-1-methylsulfanylbutan-2-ylidene)amino] n-methylcarbamate Chemical compound CNC(=O)O\N=C(C(C)(C)C)\CSC FZSVSABTBYGOQH-XFFZJAGNSA-N 0.000 description 1
- CTJBHIROCMPUKL-WEVVVXLNSA-N [(e)-3-methylsulfonylbutan-2-ylideneamino] n-methylcarbamate Chemical compound CNC(=O)O\N=C(/C)C(C)S(C)(=O)=O CTJBHIROCMPUKL-WEVVVXLNSA-N 0.000 description 1
- BZMIHNKNQJJVRO-LVZFUZTISA-N [(e)-c-(3-chloro-2,6-dimethoxyphenyl)-n-ethoxycarbonimidoyl] benzoate Chemical compound COC=1C=CC(Cl)=C(OC)C=1C(=N/OCC)\OC(=O)C1=CC=CC=C1 BZMIHNKNQJJVRO-LVZFUZTISA-N 0.000 description 1
- KAATUXNTWXVJKI-QPIRBTGLSA-N [(s)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 KAATUXNTWXVJKI-QPIRBTGLSA-N 0.000 description 1
- FSAVDKDHPDSCTO-WQLSENKSSA-N [(z)-2-chloro-1-(2,4-dichlorophenyl)ethenyl] diethyl phosphate Chemical compound CCOP(=O)(OCC)O\C(=C/Cl)C1=CC=C(Cl)C=C1Cl FSAVDKDHPDSCTO-WQLSENKSSA-N 0.000 description 1
- QSGNQELHULIMSJ-POHAHGRESA-N [(z)-2-chloro-1-(2,4-dichlorophenyl)ethenyl] dimethyl phosphate Chemical compound COP(=O)(OC)O\C(=C/Cl)C1=CC=C(Cl)C=C1Cl QSGNQELHULIMSJ-POHAHGRESA-N 0.000 description 1
- KVIZNNVXXNFLMU-AIIUZBJTSA-N [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl (1r,3r)-2,2-dimethyl-3-[(e)-prop-1-enyl]cyclopropane-1-carboxylate Chemical compound FC1=C(F)C(COC)=C(F)C(F)=C1COC(=O)[C@H]1C(C)(C)[C@@H]1\C=C\C KVIZNNVXXNFLMU-AIIUZBJTSA-N 0.000 description 1
- DPJITPZADZSLBP-PIPQINALSA-N [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl (1r,3r)-3-[(e)-2-cyanoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate Chemical compound FC1=C(F)C(COC)=C(F)C(F)=C1COC(=O)[C@H]1C(C)(C)[C@@H]1\C=C(/C)C#N DPJITPZADZSLBP-PIPQINALSA-N 0.000 description 1
- MWFQAAWRPDRKDG-KOLCDFICSA-N [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl (1r,3s)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate Chemical compound FC1=C(F)C(COC)=C(F)C(F)=C1COC(=O)[C@H]1C(C)(C)[C@@H]1C=C(Cl)Cl MWFQAAWRPDRKDG-KOLCDFICSA-N 0.000 description 1
- APEPLROGLDYWBS-UHFFFAOYSA-N [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl 2,2,3,3-tetramethylcyclopropane-1-carboxylate Chemical compound FC1=C(F)C(COC)=C(F)C(F)=C1COC(=O)C1C(C)(C)C1(C)C APEPLROGLDYWBS-UHFFFAOYSA-N 0.000 description 1
- FMPFURNXXAKYNE-UHFFFAOYSA-N [2-ethyl-3,7-dimethyl-6-[4-(trifluoromethoxy)phenoxy]quinolin-4-yl] methyl carbonate Chemical compound C1=C2C(OC(=O)OC)=C(C)C(CC)=NC2=CC(C)=C1OC1=CC=C(OC(F)(F)F)C=C1 FMPFURNXXAKYNE-UHFFFAOYSA-N 0.000 description 1
- ROVGZAWFACYCSP-MQBLHHJJSA-N [2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OC1C(C)=C(C\C=C/C=C)C(=O)C1 ROVGZAWFACYCSP-MQBLHHJJSA-N 0.000 description 1
- YDHZUCLRCLIJRL-UHFFFAOYSA-N [3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl]-pyridin-3-ylmethanol Chemical compound C=1C=CN=CC=1C(O)C=1C(C=2C(=CC(Cl)=CC=2)F)=NOC=1C1=CC=C(F)C=C1F YDHZUCLRCLIJRL-UHFFFAOYSA-N 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- YXWCBRDRVXHABN-JCMHNJIXSA-N [cyano-(4-fluoro-3-phenoxyphenyl)methyl] 3-[(z)-2-chloro-2-(4-chlorophenyl)ethenyl]-2,2-dimethylcyclopropane-1-carboxylate Chemical compound C=1C=C(F)C(OC=2C=CC=CC=2)=CC=1C(C#N)OC(=O)C1C(C)(C)C1\C=C(/Cl)C1=CC=C(Cl)C=C1 YXWCBRDRVXHABN-JCMHNJIXSA-N 0.000 description 1
- QDRXWCAVUNHOGA-UHFFFAOYSA-N acequinocyl Chemical group C1=CC=C2C(=O)C(CCCCCCCCCCCC)=C(OC(C)=O)C(=O)C2=C1 QDRXWCAVUNHOGA-UHFFFAOYSA-N 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- YLJLLELGHSWIDU-OKZTUQRJSA-N acetic acid;(2s,6r)-4-cyclododecyl-2,6-dimethylmorpholine Chemical compound CC(O)=O.C1[C@@H](C)O[C@@H](C)CN1C1CCCCCCCCCCC1 YLJLLELGHSWIDU-OKZTUQRJSA-N 0.000 description 1
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 1
- 229960004373 acetylcholine Drugs 0.000 description 1
- UELITFHSCLAHKR-UHFFFAOYSA-N acibenzolar-S-methyl Chemical group CSC(=O)C1=CC=CC2=C1SN=N2 UELITFHSCLAHKR-UHFFFAOYSA-N 0.000 description 1
- YLFSVIMMRPNPFK-WEQBUNFVSA-N acrinathrin Chemical compound CC1(C)[C@@H](\C=C/C(=O)OC(C(F)(F)F)C(F)(F)F)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 YLFSVIMMRPNPFK-WEQBUNFVSA-N 0.000 description 1
- 239000008186 active pharmaceutical agent Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 125000004442 acylamino group Chemical group 0.000 description 1
- 229960000982 afoxolaner Drugs 0.000 description 1
- GMAUQNJOSOMMHI-JXAWBTAJSA-N alanycarb Chemical compound CSC(\C)=N/OC(=O)N(C)SN(CCC(=O)OCC)CC1=CC=CC=C1 GMAUQNJOSOMMHI-JXAWBTAJSA-N 0.000 description 1
- QGLZXHRNAYXIBU-WEVVVXLNSA-N aldicarb Chemical compound CNC(=O)O\N=C\C(C)(C)SC QGLZXHRNAYXIBU-WEVVVXLNSA-N 0.000 description 1
- 239000011717 all-trans-retinol Substances 0.000 description 1
- 235000019169 all-trans-retinol Nutrition 0.000 description 1
- ZCVAOQKBXKSDMS-UHFFFAOYSA-N allethrin Chemical compound CC1(C)C(C=C(C)C)C1C(=O)OC1C(C)=C(CC=C)C(=O)C1 ZCVAOQKBXKSDMS-UHFFFAOYSA-N 0.000 description 1
- 229940024113 allethrin Drugs 0.000 description 1
- 235000020224 almond Nutrition 0.000 description 1
- UPEZCKBFRMILAV-UHFFFAOYSA-N alpha-Ecdysone Natural products C1C(O)C(O)CC2(C)C(CCC3(C(C(C(O)CCC(C)(C)O)C)CCC33O)C)C3=CC(=O)C21 UPEZCKBFRMILAV-UHFFFAOYSA-N 0.000 description 1
- PPNXXZIBFHTHDM-UHFFFAOYSA-N aluminium phosphide Chemical compound P#[Al] PPNXXZIBFHTHDM-UHFFFAOYSA-N 0.000 description 1
- GGKQIOFASHYUJZ-UHFFFAOYSA-N ametoctradin Chemical compound NC1=C(CCCCCCCC)C(CC)=NC2=NC=NN21 GGKQIOFASHYUJZ-UHFFFAOYSA-N 0.000 description 1
- 125000002344 aminooxy group Chemical group [H]N([H])O[*] 0.000 description 1
- BREATYVWRHIPIY-UHFFFAOYSA-N amisulbrom Chemical compound CN(C)S(=O)(=O)N1C=NC(S(=O)(=O)N2C3=CC(F)=CC=C3C(Br)=C2C)=N1 BREATYVWRHIPIY-UHFFFAOYSA-N 0.000 description 1
- 229960002587 amitraz Drugs 0.000 description 1
- QXAITBQSYVNQDR-ZIOPAAQOSA-N amitraz Chemical compound C=1C=C(C)C=C(C)C=1/N=C/N(C)\C=N\C1=CC=C(C)C=C1C QXAITBQSYVNQDR-ZIOPAAQOSA-N 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- IMHBYKMAHXWHRP-UHFFFAOYSA-N anilazine Chemical compound ClC1=CC=CC=C1NC1=NC(Cl)=NC(Cl)=N1 IMHBYKMAHXWHRP-UHFFFAOYSA-N 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 229940053202 antiepileptics carboxamide derivative Drugs 0.000 description 1
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 description 1
- AKNQMEBLVAMSNZ-UHFFFAOYSA-N azaconazole Chemical compound ClC1=CC(Cl)=CC=C1C1(CN2N=CN=C2)OCCO1 AKNQMEBLVAMSNZ-UHFFFAOYSA-N 0.000 description 1
- 229950000294 azaconazole Drugs 0.000 description 1
- VEHPJKVTJQSSKL-UHFFFAOYSA-N azadirachtin Natural products O1C2(C)C(C3(C=COC3O3)O)CC3C21C1(C)C(O)C(OCC2(OC(C)=O)C(CC3OC(=O)C(C)=CC)OC(C)=O)C2C32COC(C(=O)OC)(O)C12 VEHPJKVTJQSSKL-UHFFFAOYSA-N 0.000 description 1
- FTNJWQUOZFUQQJ-NDAWSKJSSA-N azadirachtin A Chemical compound C([C@@H]([C@]1(C=CO[C@H]1O1)O)[C@]2(C)O3)[C@H]1[C@]23[C@]1(C)[C@H](O)[C@H](OC[C@@]2([C@@H](C[C@@H]3OC(=O)C(\C)=C\C)OC(C)=O)C(=O)OC)[C@@H]2[C@]32CO[C@@](C(=O)OC)(O)[C@@H]12 FTNJWQUOZFUQQJ-NDAWSKJSSA-N 0.000 description 1
- FTNJWQUOZFUQQJ-IRYYUVNJSA-N azadirachtin A Natural products C([C@@H]([C@]1(C=CO[C@H]1O1)O)[C@]2(C)O3)[C@H]1[C@]23[C@]1(C)[C@H](O)[C@H](OC[C@@]2([C@@H](C[C@@H]3OC(=O)C(\C)=C/C)OC(C)=O)C(=O)OC)[C@@H]2[C@]32CO[C@@](C(=O)OC)(O)[C@@H]12 FTNJWQUOZFUQQJ-IRYYUVNJSA-N 0.000 description 1
- VNKBTWQZTQIWDV-UHFFFAOYSA-N azamethiphos Chemical compound C1=C(Cl)C=C2OC(=O)N(CSP(=O)(OC)OC)C2=N1 VNKBTWQZTQIWDV-UHFFFAOYSA-N 0.000 description 1
- RQVGAIADHNPSME-UHFFFAOYSA-N azinphos-ethyl Chemical group C1=CC=C2C(=O)N(CSP(=S)(OCC)OCC)N=NC2=C1 RQVGAIADHNPSME-UHFFFAOYSA-N 0.000 description 1
- CJJOSEISRRTUQB-UHFFFAOYSA-N azinphos-methyl Chemical group C1=CC=C2C(=O)N(CSP(=S)(OC)OC)N=NC2=C1 CJJOSEISRRTUQB-UHFFFAOYSA-N 0.000 description 1
- ONHBDDJJTDTLIR-UHFFFAOYSA-N azocyclotin Chemical compound C1CCCCC1[Sn](N1N=CN=C1)(C1CCCCC1)C1CCCCC1 ONHBDDJJTDTLIR-UHFFFAOYSA-N 0.000 description 1
- 150000003851 azoles Chemical class 0.000 description 1
- WFDXOXNFNRHQEC-GHRIWEEISA-N azoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1OC1=CC(OC=2C(=CC=CC=2)C#N)=NC=N1 WFDXOXNFNRHQEC-GHRIWEEISA-N 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- XEGGRYVFLWGFHI-UHFFFAOYSA-N bendiocarb Chemical compound CNC(=O)OC1=CC=CC2=C1OC(C)(C)O2 XEGGRYVFLWGFHI-UHFFFAOYSA-N 0.000 description 1
- LJOZMWRYMKECFF-UHFFFAOYSA-N benodanil Chemical compound IC1=CC=CC=C1C(=O)NC1=CC=CC=C1 LJOZMWRYMKECFF-UHFFFAOYSA-N 0.000 description 1
- YFXPPSKYMBTNAV-UHFFFAOYSA-N bensultap Chemical compound C=1C=CC=CC=1S(=O)(=O)SCC(N(C)C)CSS(=O)(=O)C1=CC=CC=C1 YFXPPSKYMBTNAV-UHFFFAOYSA-N 0.000 description 1
- VVSLYIKSEBPRSN-PELKAZGASA-N benthiavalicarb Chemical compound C1=C(F)C=C2SC([C@@H](C)NC(=O)[C@@H](NC(O)=O)C(C)C)=NC2=C1 VVSLYIKSEBPRSN-PELKAZGASA-N 0.000 description 1
- 150000008047 benzoylureas Chemical class 0.000 description 1
- VHLKTXFWDRXILV-UHFFFAOYSA-N bifenazate Chemical compound C1=C(NNC(=O)OC(C)C)C(OC)=CC=C1C1=CC=CC=C1 VHLKTXFWDRXILV-UHFFFAOYSA-N 0.000 description 1
- 229950002373 bioresmethrin Drugs 0.000 description 1
- 230000004790 biotic stress Effects 0.000 description 1
- 235000010290 biphenyl Nutrition 0.000 description 1
- 239000004305 biphenyl Substances 0.000 description 1
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 1
- OIPMQULDKWSNGX-UHFFFAOYSA-N bis[[ethoxy(oxo)phosphaniumyl]oxy]alumanyloxy-ethoxy-oxophosphanium Chemical compound [Al+3].CCO[P+]([O-])=O.CCO[P+]([O-])=O.CCO[P+]([O-])=O OIPMQULDKWSNGX-UHFFFAOYSA-N 0.000 description 1
- 235000021029 blackberry Nutrition 0.000 description 1
- CXNPLSGKWMLZPZ-UHFFFAOYSA-N blasticidin-S Natural products O1C(C(O)=O)C(NC(=O)CC(N)CCN(C)C(N)=N)C=CC1N1C(=O)N=C(N)C=C1 CXNPLSGKWMLZPZ-UHFFFAOYSA-N 0.000 description 1
- 229910021538 borax Inorganic materials 0.000 description 1
- QSLZKWPYTWEWHC-UHFFFAOYSA-N broflanilide Chemical compound C=1C=CC(C(=O)NC=2C(=CC(=CC=2Br)C(F)(C(F)(F)F)C(F)(F)F)C(F)(F)F)=C(F)C=1N(C)C(=O)C1=CC=CC=C1 QSLZKWPYTWEWHC-UHFFFAOYSA-N 0.000 description 1
- FOANIXZHAMJWOI-UHFFFAOYSA-N bromopropylate Chemical compound C=1C=C(Br)C=CC=1C(O)(C(=O)OC(C)C)C1=CC=C(Br)C=C1 FOANIXZHAMJWOI-UHFFFAOYSA-N 0.000 description 1
- HJJVPARKXDDIQD-UHFFFAOYSA-N bromuconazole Chemical compound ClC1=CC(Cl)=CC=C1C1(CN2N=CN=C2)OCC(Br)C1 HJJVPARKXDDIQD-UHFFFAOYSA-N 0.000 description 1
- 229960003168 bronopol Drugs 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- DSKJPMWIHSOYEA-UHFFFAOYSA-N bupirimate Chemical compound CCCCC1=C(C)N=C(NCC)N=C1OS(=O)(=O)N(C)C DSKJPMWIHSOYEA-UHFFFAOYSA-N 0.000 description 1
- SFNPDDSJBGRXLW-UITAMQMPSA-N butocarboxim Chemical compound CNC(=O)O\N=C(\C)C(C)SC SFNPDDSJBGRXLW-UITAMQMPSA-N 0.000 description 1
- KXRPCFINVWWFHQ-UHFFFAOYSA-N cadusafos Chemical compound CCC(C)SP(=O)(OCC)SC(C)CC KXRPCFINVWWFHQ-UHFFFAOYSA-N 0.000 description 1
- 235000009120 camo Nutrition 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- 229930008380 camphor Natural products 0.000 description 1
- JHRWWRDRBPCWTF-OLQVQODUSA-N captafol Chemical compound C1C=CC[C@H]2C(=O)N(SC(Cl)(Cl)C(Cl)Cl)C(=O)[C@H]21 JHRWWRDRBPCWTF-OLQVQODUSA-N 0.000 description 1
- 229940117949 captan Drugs 0.000 description 1
- 229960005286 carbaryl Drugs 0.000 description 1
- CVXBEEMKQHEXEN-UHFFFAOYSA-N carbaryl Chemical compound C1=CC=C2C(OC(=O)NC)=CC=CC2=C1 CVXBEEMKQHEXEN-UHFFFAOYSA-N 0.000 description 1
- JLQUFIHWVLZVTJ-UHFFFAOYSA-N carbosulfan Chemical compound CCCCN(CCCC)SN(C)C(=O)OC1=CC=CC2=C1OC(C)(C)C2 JLQUFIHWVLZVTJ-UHFFFAOYSA-N 0.000 description 1
- GYSSRZJIHXQEHQ-UHFFFAOYSA-N carboxin Chemical compound S1CCOC(C)=C1C(=O)NC1=CC=CC=C1 GYSSRZJIHXQEHQ-UHFFFAOYSA-N 0.000 description 1
- 235000005300 cardamomo Nutrition 0.000 description 1
- RXDMAYSSBPYBFW-UHFFFAOYSA-N carpropamid Chemical compound C=1C=C(Cl)C=CC=1C(C)NC(=O)C1(CC)C(C)C1(Cl)Cl RXDMAYSSBPYBFW-UHFFFAOYSA-N 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 235000005607 chanvre indien Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000019693 cherries Nutrition 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- BIWJNBZANLAXMG-YQELWRJZSA-N chloordaan Chemical compound ClC1=C(Cl)[C@@]2(Cl)C3CC(Cl)C(Cl)C3[C@]1(Cl)C2(Cl)Cl BIWJNBZANLAXMG-YQELWRJZSA-N 0.000 description 1
- XFDJMIHUAHSGKG-UHFFFAOYSA-N chlorethoxyfos Chemical compound CCOP(=S)(OCC)OC(Cl)C(Cl)(Cl)Cl XFDJMIHUAHSGKG-UHFFFAOYSA-N 0.000 description 1
- UISUNVFOGSJSKD-UHFFFAOYSA-N chlorfluazuron Chemical compound FC1=CC=CC(F)=C1C(=O)NC(=O)NC(C=C1Cl)=CC(Cl)=C1OC1=NC=C(C(F)(F)F)C=C1Cl UISUNVFOGSJSKD-UHFFFAOYSA-N 0.000 description 1
- QGTYWWGEWOBMAK-UHFFFAOYSA-N chlormephos Chemical compound CCOP(=S)(OCC)SCCl QGTYWWGEWOBMAK-UHFFFAOYSA-N 0.000 description 1
- HKMOPYJWSFRURD-UHFFFAOYSA-N chloro hypochlorite;copper Chemical compound [Cu].ClOCl HKMOPYJWSFRURD-UHFFFAOYSA-N 0.000 description 1
- PFIADAMVCJPXSF-UHFFFAOYSA-N chloroneb Chemical compound COC1=CC(Cl)=C(OC)C=C1Cl PFIADAMVCJPXSF-UHFFFAOYSA-N 0.000 description 1
- LFHISGNCFUNFFM-UHFFFAOYSA-N chloropicrin Chemical compound [O-][N+](=O)C(Cl)(Cl)Cl LFHISGNCFUNFFM-UHFFFAOYSA-N 0.000 description 1
- HPNSNYBUADCFDR-UHFFFAOYSA-N chromafenozide Chemical compound CC1=CC(C)=CC(C(=O)N(NC(=O)C=2C(=C3CCCOC3=CC=2)C)C(C)(C)C)=C1 HPNSNYBUADCFDR-UHFFFAOYSA-N 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- UXADOQPNKNTIHB-UHFFFAOYSA-N clofentezine Chemical compound ClC1=CC=CC=C1C1=NN=C(C=2C(=CC=CC=2)Cl)N=N1 UXADOQPNKNTIHB-UHFFFAOYSA-N 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 229910001956 copper hydroxide Inorganic materials 0.000 description 1
- OPQARKPSCNTWTJ-UHFFFAOYSA-L copper(ii) acetate Chemical compound [Cu+2].CC([O-])=O.CC([O-])=O OPQARKPSCNTWTJ-UHFFFAOYSA-L 0.000 description 1
- BXNANOICGRISHX-UHFFFAOYSA-N coumaphos Chemical compound CC1=C(Cl)C(=O)OC2=CC(OP(=S)(OCC)OCC)=CC=C21 BXNANOICGRISHX-UHFFFAOYSA-N 0.000 description 1
- CWVRPJSBNHNJSI-XQNSMLJCSA-N coumoxystrobin Chemical compound C1=C2OC(=O)C(CCCC)=C(C)C2=CC=C1OCC1=CC=CC=C1\C(=C/OC)C(=O)OC CWVRPJSBNHNJSI-XQNSMLJCSA-N 0.000 description 1
- 229910001610 cryolite Inorganic materials 0.000 description 1
- SCKHCCSZFPSHGR-UHFFFAOYSA-N cyanophos Chemical compound COP(=S)(OC)OC1=CC=C(C#N)C=C1 SCKHCCSZFPSHGR-UHFFFAOYSA-N 0.000 description 1
- YXKMMRDKEKCERS-UHFFFAOYSA-N cyazofamid Chemical compound CN(C)S(=O)(=O)N1C(C#N)=NC(Cl)=C1C1=CC=C(C)C=C1 YXKMMRDKEKCERS-UHFFFAOYSA-N 0.000 description 1
- 125000004122 cyclic group Chemical class 0.000 description 1
- LSFUGNKKPMBOMG-UHFFFAOYSA-N cycloprothrin Chemical compound ClC1(Cl)CC1(C=1C=CC=CC=1)C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 LSFUGNKKPMBOMG-UHFFFAOYSA-N 0.000 description 1
- APJLTUBHYCOZJI-VZCXRCSSSA-N cyenopyrafen Chemical compound CC1=NN(C)C(\C(OC(=O)C(C)(C)C)=C(/C#N)C=2C=CC(=CC=2)C(C)(C)C)=C1C APJLTUBHYCOZJI-VZCXRCSSSA-N 0.000 description 1
- ACMXQHFNODYQAT-UHFFFAOYSA-N cyflufenamid Chemical compound FC1=CC=C(C(F)(F)F)C(C(NOCC2CC2)=NC(=O)CC=2C=CC=CC=2)=C1F ACMXQHFNODYQAT-UHFFFAOYSA-N 0.000 description 1
- 229960001591 cyfluthrin Drugs 0.000 description 1
- QQODLKZGRKWIFG-QSFXBCCZSA-N cyfluthrin Chemical compound CC1(C)[C@@H](C=C(Cl)Cl)[C@H]1C(=O)O[C@@H](C#N)C1=CC=C(F)C(OC=2C=CC=CC=2)=C1 QQODLKZGRKWIFG-QSFXBCCZSA-N 0.000 description 1
- WCMMILVIRZAPLE-UHFFFAOYSA-M cyhexatin Chemical compound C1CCCCC1[Sn](C1CCCCC1)(O)C1CCCCC1 WCMMILVIRZAPLE-UHFFFAOYSA-M 0.000 description 1
- KAATUXNTWXVJKI-UHFFFAOYSA-N cypermethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 KAATUXNTWXVJKI-UHFFFAOYSA-N 0.000 description 1
- 229960005424 cypermethrin Drugs 0.000 description 1
- HAORKNGNJCEJBX-UHFFFAOYSA-N cyprodinil Chemical compound N=1C(C)=CC(C2CC2)=NC=1NC1=CC=CC=C1 HAORKNGNJCEJBX-UHFFFAOYSA-N 0.000 description 1
- LVQDKIWDGQRHTE-UHFFFAOYSA-N cyromazine Chemical compound NC1=NC(N)=NC(NC2CC2)=N1 LVQDKIWDGQRHTE-UHFFFAOYSA-N 0.000 description 1
- 229950000775 cyromazine Drugs 0.000 description 1
- 208000031513 cyst Diseases 0.000 description 1
- 210000004292 cytoskeleton Anatomy 0.000 description 1
- 229940008203 d-transallethrin Drugs 0.000 description 1
- QAYICIQNSGETAS-UHFFFAOYSA-N dazomet Chemical compound CN1CSC(=S)N(C)C1 QAYICIQNSGETAS-UHFFFAOYSA-N 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 229960002483 decamethrin Drugs 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- OWZREIFADZCYQD-NSHGMRRFSA-N deltamethrin Chemical compound CC1(C)[C@@H](C=C(Br)Br)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 OWZREIFADZCYQD-NSHGMRRFSA-N 0.000 description 1
- WEBQKRLKWNIYKK-UHFFFAOYSA-N demeton-S-methyl Chemical compound CCSCCSP(=O)(OC)OC WEBQKRLKWNIYKK-UHFFFAOYSA-N 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 150000008037 diacylhydrazines Chemical class 0.000 description 1
- WOWBFOBYOAGEEA-UHFFFAOYSA-N diafenthiuron Chemical compound CC(C)C1=C(NC(=S)NC(C)(C)C)C(C(C)C)=CC(OC=2C=CC=CC=2)=C1 WOWBFOBYOAGEEA-UHFFFAOYSA-N 0.000 description 1
- 150000001470 diamides Chemical class 0.000 description 1
- FHIVAFMUCKRCQO-UHFFFAOYSA-N diazinon Chemical compound CCOP(=S)(OCC)OC1=CC(C)=NC(C(C)C)=N1 FHIVAFMUCKRCQO-UHFFFAOYSA-N 0.000 description 1
- WURGXGVFSMYFCG-UHFFFAOYSA-N dichlofluanid Chemical compound CN(C)S(=O)(=O)N(SC(F)(Cl)Cl)C1=CC=CC=C1 WURGXGVFSMYFCG-UHFFFAOYSA-N 0.000 description 1
- BIXZHMJUSMUDOQ-UHFFFAOYSA-N dichloran Chemical compound NC1=C(Cl)C=C([N+]([O-])=O)C=C1Cl BIXZHMJUSMUDOQ-UHFFFAOYSA-N 0.000 description 1
- 229960003887 dichlorophen Drugs 0.000 description 1
- 229950001327 dichlorvos Drugs 0.000 description 1
- YEJGPFZQLRMXOI-PKEIRNPWSA-N diclocymet Chemical compound N#CC(C(C)(C)C)C(=O)N[C@H](C)C1=CC=C(Cl)C=C1Cl YEJGPFZQLRMXOI-PKEIRNPWSA-N 0.000 description 1
- UWQMKVBQKFHLCE-UHFFFAOYSA-N diclomezine Chemical compound C1=C(Cl)C(C)=C(Cl)C=C1C1=NNC(=O)C=C1 UWQMKVBQKFHLCE-UHFFFAOYSA-N 0.000 description 1
- 229940004812 dicloran Drugs 0.000 description 1
- PVDQXPBKBSCNJZ-UHFFFAOYSA-N dicloromezotiaz Chemical compound CC1=CC=C[N+](C(C(C=2C=C(Cl)C=C(Cl)C=2)=C2[O-])=O)=C1N2CC1=CN=C(Cl)S1 PVDQXPBKBSCNJZ-UHFFFAOYSA-N 0.000 description 1
- UOAMTSKGCBMZTC-UHFFFAOYSA-N dicofol Chemical compound C=1C=C(Cl)C=CC=1C(C(Cl)(Cl)Cl)(O)C1=CC=C(Cl)C=C1 UOAMTSKGCBMZTC-UHFFFAOYSA-N 0.000 description 1
- VEENJGZXVHKXNB-VOTSOKGWSA-N dicrotophos Chemical compound COP(=O)(OC)O\C(C)=C\C(=O)N(C)C VEENJGZXVHKXNB-VOTSOKGWSA-N 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- LNJNFVJKDJYTEU-UHFFFAOYSA-N diethofencarb Chemical compound CCOC1=CC=C(NC(=O)OC(C)C)C=C1OCC LNJNFVJKDJYTEU-UHFFFAOYSA-N 0.000 description 1
- JXSJBGJIGXNWCI-UHFFFAOYSA-N diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate Chemical compound CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC JXSJBGJIGXNWCI-UHFFFAOYSA-N 0.000 description 1
- BQYJATMQXGBDHF-UHFFFAOYSA-N difenoconazole Chemical compound O1C(C)COC1(C=1C(=CC(OC=2C=CC(Cl)=CC=2)=CC=1)Cl)CN1N=CN=C1 BQYJATMQXGBDHF-UHFFFAOYSA-N 0.000 description 1
- 229940019503 diflubenzuron Drugs 0.000 description 1
- MCWXGJITAZMZEV-UHFFFAOYSA-N dimethoate Chemical compound CNC(=O)CSP(=S)(OC)OC MCWXGJITAZMZEV-UHFFFAOYSA-N 0.000 description 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- WXUZAHCNPWONDH-DYTRJAOYSA-N dimoxystrobin Chemical compound CNC(=O)C(=N\OC)\C1=CC=CC=C1COC1=CC(C)=CC=C1C WXUZAHCNPWONDH-DYTRJAOYSA-N 0.000 description 1
- DMBHHRLKUKUOEG-UHFFFAOYSA-N diphenylamine Chemical compound C=1C=CC=CC=1NC1=CC=CC=C1 DMBHHRLKUKUOEG-UHFFFAOYSA-N 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- FPKXBFWMIYHCID-UHFFFAOYSA-N dipymetitrone Chemical compound S1C=2C(=O)N(C)C(=O)C=2SC2=C1C(=O)N(C)C2=O FPKXBFWMIYHCID-UHFFFAOYSA-N 0.000 description 1
- DOFZAZXDOSGAJZ-UHFFFAOYSA-N disulfoton Chemical compound CCOP(=S)(OCC)SCCSCC DOFZAZXDOSGAJZ-UHFFFAOYSA-N 0.000 description 1
- 239000012990 dithiocarbamate Substances 0.000 description 1
- 150000004659 dithiocarbamates Chemical class 0.000 description 1
- 230000024346 drought recovery Effects 0.000 description 1
- AWZOLILCOUMRDG-UHFFFAOYSA-N edifenphos Chemical compound C=1C=CC=CC=1SP(=O)(OCC)SC1=CC=CC=C1 AWZOLILCOUMRDG-UHFFFAOYSA-N 0.000 description 1
- 230000000459 effect on growth Effects 0.000 description 1
- 239000002895 emetic Substances 0.000 description 1
- RDYMFSUJUZBWLH-SVWSLYAFSA-N endosulfan Chemical compound C([C@@H]12)OS(=O)OC[C@@H]1[C@]1(Cl)C(Cl)=C(Cl)[C@@]2(Cl)C1(Cl)Cl RDYMFSUJUZBWLH-SVWSLYAFSA-N 0.000 description 1
- 229960002125 enilconazole Drugs 0.000 description 1
- VMNULHCTRPXWFJ-UJSVPXBISA-N enoxastrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1CO\N=C(/C)\C=C\C1=CC=C(Cl)C=C1 VMNULHCTRPXWFJ-UJSVPXBISA-N 0.000 description 1
- NYPJDWWKZLNGGM-RPWUZVMVSA-N esfenvalerate Chemical compound C=1C([C@@H](C#N)OC(=O)[C@@H](C(C)C)C=2C=CC(Cl)=CC=2)=CC=CC=1OC1=CC=CC=C1 NYPJDWWKZLNGGM-RPWUZVMVSA-N 0.000 description 1
- 230000012173 estrus Effects 0.000 description 1
- HEZNVIYQEUHLNI-UHFFFAOYSA-N ethiofencarb Chemical compound CCSCC1=CC=CC=C1OC(=O)NC HEZNVIYQEUHLNI-UHFFFAOYSA-N 0.000 description 1
- RIZMRRKBZQXFOY-UHFFFAOYSA-N ethion Chemical compound CCOP(=S)(OCC)SCSP(=S)(OCC)OCC RIZMRRKBZQXFOY-UHFFFAOYSA-N 0.000 description 1
- VJYFKVYYMZPMAB-UHFFFAOYSA-N ethoprophos Chemical compound CCCSP(=O)(OCC)SCCC VJYFKVYYMZPMAB-UHFFFAOYSA-N 0.000 description 1
- YKRQBWKLHCEKQH-KHPPLWFESA-N ethyl (z)-3-amino-2-cyano-3-phenylprop-2-enoate Chemical compound CCOC(=O)C(\C#N)=C(/N)C1=CC=CC=C1 YKRQBWKLHCEKQH-KHPPLWFESA-N 0.000 description 1
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 description 1
- YREQHYQNNWYQCJ-UHFFFAOYSA-N etofenprox Chemical compound C1=CC(OCC)=CC=C1C(C)(C)COCC1=CC=CC(OC=2C=CC=CC=2)=C1 YREQHYQNNWYQCJ-UHFFFAOYSA-N 0.000 description 1
- 229950005085 etofenprox Drugs 0.000 description 1
- KQTVWCSONPJJPE-UHFFFAOYSA-N etridiazole Chemical compound CCOC1=NC(C(Cl)(Cl)Cl)=NS1 KQTVWCSONPJJPE-UHFFFAOYSA-N 0.000 description 1
- JISACBWYRJHSMG-UHFFFAOYSA-N famphur Chemical compound COP(=S)(OC)OC1=CC=C(S(=O)(=O)N(C)C)C=C1 JISACBWYRJHSMG-UHFFFAOYSA-N 0.000 description 1
- 125000005313 fatty acid group Chemical group 0.000 description 1
- LMVPQMGRYSRMIW-KRWDZBQOSA-N fenamidone Chemical compound O=C([C@@](C)(N=C1SC)C=2C=CC=CC=2)N1NC1=CC=CC=C1 LMVPQMGRYSRMIW-KRWDZBQOSA-N 0.000 description 1
- RBWGTZRSEOIHFD-UHUFKFKFSA-N fenaminstrobin Chemical compound CNC(=O)C(=N\OC)\C1=CC=CC=C1CO\N=C(/C)\C=C\C1=C(Cl)C=CC=C1Cl RBWGTZRSEOIHFD-UHUFKFKFSA-N 0.000 description 1
- ZCJPOPBZHLUFHF-UHFFFAOYSA-N fenamiphos Chemical compound CCOP(=O)(NC(C)C)OC1=CC=C(SC)C(C)=C1 ZCJPOPBZHLUFHF-UHFFFAOYSA-N 0.000 description 1
- DMYHGDXADUDKCQ-UHFFFAOYSA-N fenazaquin Chemical compound C1=CC(C(C)(C)C)=CC=C1CCOC1=NC=NC2=CC=CC=C12 DMYHGDXADUDKCQ-UHFFFAOYSA-N 0.000 description 1
- JFSPBVWPKOEZCB-UHFFFAOYSA-N fenfuram Chemical compound O1C=CC(C(=O)NC=2C=CC=CC=2)=C1C JFSPBVWPKOEZCB-UHFFFAOYSA-N 0.000 description 1
- VDLGAVXLJYLFDH-UHFFFAOYSA-N fenhexamid Chemical compound C=1C=C(O)C(Cl)=C(Cl)C=1NC(=O)C1(C)CCCCC1 VDLGAVXLJYLFDH-UHFFFAOYSA-N 0.000 description 1
- ZNOLGFHPUIJIMJ-UHFFFAOYSA-N fenitrothion Chemical compound COP(=S)(OC)OC1=CC=C([N+]([O-])=O)C(C)=C1 ZNOLGFHPUIJIMJ-UHFFFAOYSA-N 0.000 description 1
- DIRFUJHNVNOBMY-UHFFFAOYSA-N fenobucarb Chemical compound CCC(C)C1=CC=CC=C1OC(=O)NC DIRFUJHNVNOBMY-UHFFFAOYSA-N 0.000 description 1
- HJUFTIJOISQSKQ-UHFFFAOYSA-N fenoxycarb Chemical compound C1=CC(OCCNC(=O)OCC)=CC=C1OC1=CC=CC=C1 HJUFTIJOISQSKQ-UHFFFAOYSA-N 0.000 description 1
- XQUXKZZNEFRCAW-UHFFFAOYSA-N fenpropathrin Chemical compound CC1(C)C(C)(C)C1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 XQUXKZZNEFRCAW-UHFFFAOYSA-N 0.000 description 1
- UTOHZQYBSYOOGC-UHFFFAOYSA-N fenpyrazamine Chemical compound O=C1N(C(C)C)N(C(=O)SCC=C)C(N)=C1C1=CC=CC=C1C UTOHZQYBSYOOGC-UHFFFAOYSA-N 0.000 description 1
- WDQNIWFZKXZFAY-UHFFFAOYSA-M fentin acetate Chemical compound CC([O-])=O.C1=CC=CC=C1[Sn+](C=1C=CC=CC=1)C1=CC=CC=C1 WDQNIWFZKXZFAY-UHFFFAOYSA-M 0.000 description 1
- NJVOZLGKTAPUTQ-UHFFFAOYSA-M fentin chloride Chemical compound C=1C=CC=CC=1[Sn](C=1C=CC=CC=1)(Cl)C1=CC=CC=C1 NJVOZLGKTAPUTQ-UHFFFAOYSA-M 0.000 description 1
- WHDGWKAJBYRJJL-UHFFFAOYSA-K ferbam Chemical compound [Fe+3].CN(C)C([S-])=S.CN(C)C([S-])=S.CN(C)C([S-])=S WHDGWKAJBYRJJL-UHFFFAOYSA-K 0.000 description 1
- GOWLARCWZRESHU-AQTBWJFISA-N ferimzone Chemical compound C=1C=CC=C(C)C=1C(/C)=N\NC1=NC(C)=CC(C)=N1 GOWLARCWZRESHU-AQTBWJFISA-N 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 235000004426 flaxseed Nutrition 0.000 description 1
- MXWAGQASUDSFBG-RVDMUPIBSA-N fluacrypyrim Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1COC1=CC(C(F)(F)F)=NC(OC(C)C)=N1 MXWAGQASUDSFBG-RVDMUPIBSA-N 0.000 description 1
- PHCCDUCBMCYSNQ-UHFFFAOYSA-N fluazaindolizine Chemical compound COC1=CC=C(Cl)C(S(=O)(=O)NC(=O)C=2N=C3C(Cl)=CC(=CN3C=2)C(F)(F)F)=C1 PHCCDUCBMCYSNQ-UHFFFAOYSA-N 0.000 description 1
- UZCGKGPEKUCDTF-UHFFFAOYSA-N fluazinam Chemical compound [O-][N+](=O)C1=CC(C(F)(F)F)=C(Cl)C([N+]([O-])=O)=C1NC1=NC=C(C(F)(F)F)C=C1Cl UZCGKGPEKUCDTF-UHFFFAOYSA-N 0.000 description 1
- ZGNITFSDLCMLGI-UHFFFAOYSA-N flubendiamide Chemical compound CC1=CC(C(F)(C(F)(F)F)C(F)(F)F)=CC=C1NC(=O)C1=CC=CC(I)=C1C(=O)NC(C)(C)CS(C)(=O)=O ZGNITFSDLCMLGI-UHFFFAOYSA-N 0.000 description 1
- GBIHOLCMZGAKNG-CGAIIQECSA-N flucythrinate Chemical compound O=C([C@@H](C(C)C)C=1C=CC(OC(F)F)=CC=1)OC(C#N)C(C=1)=CC=CC=1OC1=CC=CC=C1 GBIHOLCMZGAKNG-CGAIIQECSA-N 0.000 description 1
- XRECTZIEBJDKEO-UHFFFAOYSA-N flucytosine Chemical compound NC1=NC(=O)NC=C1F XRECTZIEBJDKEO-UHFFFAOYSA-N 0.000 description 1
- 229960004413 flucytosine Drugs 0.000 description 1
- MUJOIMFVNIBMKC-UHFFFAOYSA-N fludioxonil Chemical compound C=12OC(F)(F)OC2=CC=CC=1C1=CNC=C1C#N MUJOIMFVNIBMKC-UHFFFAOYSA-N 0.000 description 1
- XSNMWAPKHUGZGQ-UHFFFAOYSA-N fluensulfone Chemical compound FC(F)=C(F)CCS(=O)(=O)C1=NC=C(Cl)S1 XSNMWAPKHUGZGQ-UHFFFAOYSA-N 0.000 description 1
- GJEREQYJIQASAW-UHFFFAOYSA-N flufenerim Chemical compound CC(F)C1=NC=NC(NCCC=2C=CC(OC(F)(F)F)=CC=2)=C1Cl GJEREQYJIQASAW-UHFFFAOYSA-N 0.000 description 1
- RYLHNOVXKPXDIP-UHFFFAOYSA-N flufenoxuron Chemical compound C=1C=C(NC(=O)NC(=O)C=2C(=CC=CC=2F)F)C(F)=CC=1OC1=CC=C(C(F)(F)F)C=C1Cl RYLHNOVXKPXDIP-UHFFFAOYSA-N 0.000 description 1
- MBHXIQDIVCJZTD-RVDMUPIBSA-N flufenoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1COC1=CC=C(C(F)(F)F)C=C1Cl MBHXIQDIVCJZTD-RVDMUPIBSA-N 0.000 description 1
- GBOYJIHYACSLGN-UHFFFAOYSA-N fluopicolide Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CNC(=O)C1=C(Cl)C=CC=C1Cl GBOYJIHYACSLGN-UHFFFAOYSA-N 0.000 description 1
- MLBZKOGAMRTSKP-UHFFFAOYSA-N fluralaner Chemical compound C1=C(C(=O)NCC(=O)NCC(F)(F)F)C(C)=CC(C=2CC(ON=2)(C=2C=C(Cl)C=C(Cl)C=2)C(F)(F)F)=C1 MLBZKOGAMRTSKP-UHFFFAOYSA-N 0.000 description 1
- 229960004498 fluralaner Drugs 0.000 description 1
- KGXUEPOHGFWQKF-ZCXUNETKSA-N flutianil Chemical compound COC1=CC=CC=C1N(CCS\1)C/1=C(C#N)/SC1=CC(C(F)(F)F)=CC=C1F KGXUEPOHGFWQKF-ZCXUNETKSA-N 0.000 description 1
- PTCGDEVVHUXTMP-UHFFFAOYSA-N flutolanil Chemical compound CC(C)OC1=CC=CC(NC(=O)C=2C(=CC=CC=2)C(F)(F)F)=C1 PTCGDEVVHUXTMP-UHFFFAOYSA-N 0.000 description 1
- HKIOYBQGHSTUDB-UHFFFAOYSA-N folpet Chemical compound C1=CC=C2C(=O)N(SC(Cl)(Cl)Cl)C(=O)C2=C1 HKIOYBQGHSTUDB-UHFFFAOYSA-N 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 238000005755 formation reaction Methods 0.000 description 1
- RMFNNCGOSPBBAD-MDWZMJQESA-N formetanate Chemical compound CNC(=O)OC1=CC=CC(\N=C\N(C)C)=C1 RMFNNCGOSPBBAD-MDWZMJQESA-N 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- VUERQRKTYBIULR-UHFFFAOYSA-N fosetyl Chemical compound CCOP(O)=O VUERQRKTYBIULR-UHFFFAOYSA-N 0.000 description 1
- DUFVKSUJRWYZQP-UHFFFAOYSA-N fosthiazate Chemical compound CCC(C)SP(=O)(OCC)N1CCSC1=O DUFVKSUJRWYZQP-UHFFFAOYSA-N 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- ZEYJIQLVKGBLEM-UHFFFAOYSA-N fuberidazole Chemical compound C1=COC(C=2N=C3[CH]C=CC=C3N=2)=C1 ZEYJIQLVKGBLEM-UHFFFAOYSA-N 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- HAWJXYBZNNRMNO-UHFFFAOYSA-N furathiocarb Chemical compound CCCCOC(=O)N(C)SN(C)C(=O)OC1=CC=CC2=C1OC(C)(C)C2 HAWJXYBZNNRMNO-UHFFFAOYSA-N 0.000 description 1
- ZXQYGBMAQZUVMI-GCMPRSNUSA-N gamma-cyhalothrin Chemical compound CC1(C)[C@@H](\C=C(/Cl)C(F)(F)F)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 ZXQYGBMAQZUVMI-GCMPRSNUSA-N 0.000 description 1
- 230000030279 gene silencing Effects 0.000 description 1
- 230000035784 germination Effects 0.000 description 1
- 235000019674 grape juice Nutrition 0.000 description 1
- 150000002357 guanidines Chemical class 0.000 description 1
- WIFXJBMOTMKRMM-UHFFFAOYSA-N halfenprox Chemical compound C=1C=C(OC(F)(F)Br)C=CC=1C(C)(C)COCC(C=1)=CC=CC=1OC1=CC=CC=C1 WIFXJBMOTMKRMM-UHFFFAOYSA-N 0.000 description 1
- CNKHSLKYRMDDNQ-UHFFFAOYSA-N halofenozide Chemical compound C=1C=CC=CC=1C(=O)N(C(C)(C)C)NC(=O)C1=CC=C(Cl)C=C1 CNKHSLKYRMDDNQ-UHFFFAOYSA-N 0.000 description 1
- 244000000013 helminth Species 0.000 description 1
- 239000011487 hemp Substances 0.000 description 1
- BKACAEJQMLLGAV-PLNGDYQASA-N heptafluthrin Chemical compound FC1=C(F)C(COC)=C(F)C(F)=C1COC(=O)C1C(C)(C)C1\C=C/C(F)(F)F BKACAEJQMLLGAV-PLNGDYQASA-N 0.000 description 1
- CKAPSXZOOQJIBF-UHFFFAOYSA-N hexachlorobenzene Chemical compound ClC1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl CKAPSXZOOQJIBF-UHFFFAOYSA-N 0.000 description 1
- RGNPBRKPHBKNKX-UHFFFAOYSA-N hexaflumuron Chemical compound C1=C(Cl)C(OC(F)(F)C(F)F)=C(Cl)C=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F RGNPBRKPHBKNKX-UHFFFAOYSA-N 0.000 description 1
- FYQGBXGJFWXIPP-UHFFFAOYSA-N hydroprene Chemical compound CCOC(=O)C=C(C)C=CCC(C)CCCC(C)C FYQGBXGJFWXIPP-UHFFFAOYSA-N 0.000 description 1
- 229930000073 hydroprene Natural products 0.000 description 1
- KGVPNLBXJKTABS-UHFFFAOYSA-N hymexazol Chemical compound CC1=CC(O)=NO1 KGVPNLBXJKTABS-UHFFFAOYSA-N 0.000 description 1
- HICUREFSAIZXFQ-JOWPUVSESA-N i9z29i000j Chemical compound C1C[C@H](C)[C@@H](CC)O[C@@]21O[C@H](C\C=C(C)\[C@H](OC(=O)C(=N/OC)\C=1C=CC=CC=1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 HICUREFSAIZXFQ-JOWPUVSESA-N 0.000 description 1
- AGKSTYPVMZODRV-UHFFFAOYSA-N imibenconazole Chemical compound C1=CC(Cl)=CC=C1CSC(CN1N=CN=C1)=NC1=CC=C(Cl)C=C1Cl AGKSTYPVMZODRV-UHFFFAOYSA-N 0.000 description 1
- 150000002460 imidazoles Chemical class 0.000 description 1
- VPRAQYXPZIFIOH-UHFFFAOYSA-N imiprothrin Chemical compound CC1(C)C(C=C(C)C)C1C(=O)OCN1C(=O)N(CC#C)CC1=O VPRAQYXPZIFIOH-UHFFFAOYSA-N 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000000411 inducer Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- QTYCMDBMOLSEAM-UHFFFAOYSA-N ipconazole Chemical compound C1=NC=NN1CC1(O)C(C(C)C)CCC1CC1=CC=C(Cl)C=C1 QTYCMDBMOLSEAM-UHFFFAOYSA-N 0.000 description 1
- FCOAHACKGGIURQ-UHFFFAOYSA-N iprobenfos Chemical compound CC(C)OP(=O)(OC(C)C)SCC1=CC=CC=C1 FCOAHACKGGIURQ-UHFFFAOYSA-N 0.000 description 1
- ONUFESLQCSAYKA-UHFFFAOYSA-N iprodione Chemical compound O=C1N(C(=O)NC(C)C)CC(=O)N1C1=CC(Cl)=CC(Cl)=C1 ONUFESLQCSAYKA-UHFFFAOYSA-N 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- YFVOXLJXJBQDEF-UHFFFAOYSA-N isocarbophos Chemical compound COP(N)(=S)OC1=CC=CC=C1C(=O)OC(C)C YFVOXLJXJBQDEF-UHFFFAOYSA-N 0.000 description 1
- HOQADATXFBOEGG-UHFFFAOYSA-N isofenphos Chemical compound CCOP(=S)(NC(C)C)OC1=CC=CC=C1C(=O)OC(C)C HOQADATXFBOEGG-UHFFFAOYSA-N 0.000 description 1
- WMKZDPFZIZQROT-UHFFFAOYSA-N isofetamid Chemical compound CC1=CC(OC(C)C)=CC=C1C(=O)C(C)(C)NC(=O)C1=C(C)C=CS1 WMKZDPFZIZQROT-UHFFFAOYSA-N 0.000 description 1
- QBSJMKIUCUGGNG-UHFFFAOYSA-N isoprocarb Chemical compound CNC(=O)OC1=CC=CC=C1C(C)C QBSJMKIUCUGGNG-UHFFFAOYSA-N 0.000 description 1
- UFHLMYOGRXOCSL-UHFFFAOYSA-N isoprothiolane Chemical compound CC(C)OC(=O)C(C(=O)OC(C)C)=C1SCCS1 UFHLMYOGRXOCSL-UHFFFAOYSA-N 0.000 description 1
- WLPCAERCXQSYLQ-UHFFFAOYSA-N isotianil Chemical compound ClC1=NSC(C(=O)NC=2C(=CC=CC=2)C#N)=C1Cl WLPCAERCXQSYLQ-UHFFFAOYSA-N 0.000 description 1
- SDMSCIWHRZJSRN-UHFFFAOYSA-N isoxathion Chemical compound O1N=C(OP(=S)(OCC)OCC)C=C1C1=CC=CC=C1 SDMSCIWHRZJSRN-UHFFFAOYSA-N 0.000 description 1
- 229960002418 ivermectin Drugs 0.000 description 1
- PVTHJAPFENJVNC-MHRBZPPQSA-N kasugamycin Chemical compound N[C@H]1C[C@H](NC(=N)C(O)=O)[C@@H](C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O PVTHJAPFENJVNC-MHRBZPPQSA-N 0.000 description 1
- 229940043355 kinase inhibitor Drugs 0.000 description 1
- 229930001540 kinoprene Natural products 0.000 description 1
- ZOTBXTZVPHCKPN-HTXNQAPBSA-N kresoxim-methyl Chemical compound CO\N=C(\C(=O)OC)C1=CC=CC=C1COC1=CC=CC=C1C ZOTBXTZVPHCKPN-HTXNQAPBSA-N 0.000 description 1
- 239000005910 lambda-Cyhalothrin Substances 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 230000003859 lipid peroxidation Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229950002303 lotilaner Drugs 0.000 description 1
- 229960000521 lufenuron Drugs 0.000 description 1
- PWPJGUXAGUPAHP-UHFFFAOYSA-N lufenuron Chemical compound C1=C(Cl)C(OC(F)(F)C(C(F)(F)F)F)=CC(Cl)=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F PWPJGUXAGUPAHP-UHFFFAOYSA-N 0.000 description 1
- 229960000453 malathion Drugs 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- KLGMSAOQDHLCOS-UHFFFAOYSA-N mecarbam Chemical compound CCOC(=O)N(C)C(=O)CSP(=S)(OCC)OCC KLGMSAOQDHLCOS-UHFFFAOYSA-N 0.000 description 1
- CIFWZNRJIBNXRE-UHFFFAOYSA-N mepanipyrim Chemical compound CC#CC1=CC(C)=NC(NC=2C=CC=CC=2)=N1 CIFWZNRJIBNXRE-UHFFFAOYSA-N 0.000 description 1
- BCTQJXQXJVLSIG-UHFFFAOYSA-N mepronil Chemical compound CC(C)OC1=CC=CC(NC(=O)C=2C(=CC=CC=2)C)=C1 BCTQJXQXJVLSIG-UHFFFAOYSA-N 0.000 description 1
- ZQEIXNIJLIKNTD-GFCCVEGCSA-N metalaxyl-M Chemical compound COCC(=O)N([C@H](C)C(=O)OC)C1=C(C)C=CC=C1C ZQEIXNIJLIKNTD-GFCCVEGCSA-N 0.000 description 1
- HYVVJDQGXFXBRZ-UHFFFAOYSA-N metam Chemical compound CNC(S)=S HYVVJDQGXFXBRZ-UHFFFAOYSA-N 0.000 description 1
- NNKVPIKMPCQWCG-UHFFFAOYSA-N methamidophos Chemical compound COP(N)(=O)SC NNKVPIKMPCQWCG-UHFFFAOYSA-N 0.000 description 1
- IXJOSTZEBSTPAG-UHFFFAOYSA-N methasulfocarb Chemical compound CNC(=O)SC1=CC=C(OS(C)(=O)=O)C=C1 IXJOSTZEBSTPAG-UHFFFAOYSA-N 0.000 description 1
- MEBQXILRKZHVCX-UHFFFAOYSA-N methidathion Chemical compound COC1=NN(CSP(=S)(OC)OC)C(=O)S1 MEBQXILRKZHVCX-UHFFFAOYSA-N 0.000 description 1
- YFBPRJGDJKVWAH-UHFFFAOYSA-N methiocarb Chemical compound CNC(=O)OC1=CC(C)=C(SC)C(C)=C1 YFBPRJGDJKVWAH-UHFFFAOYSA-N 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 229930002897 methoprene Natural products 0.000 description 1
- 229950003442 methoprene Drugs 0.000 description 1
- QCAWEPFNJXQPAN-UHFFFAOYSA-N methoxyfenozide Chemical compound COC1=CC=CC(C(=O)NN(C(=O)C=2C=C(C)C=C(C)C=2)C(C)(C)C)=C1C QCAWEPFNJXQPAN-UHFFFAOYSA-N 0.000 description 1
- SPTIHHXLKJKKNM-WQLSENKSSA-N methyl (Z)-3-(fluoromethoxy)-2-[2-[(3,5,6-trichloropyridin-2-yl)oxymethyl]phenyl]prop-2-enoate Chemical compound COC(=O)C(=C/OCF)\c1ccccc1COc1nc(Cl)c(Cl)cc1Cl SPTIHHXLKJKKNM-WQLSENKSSA-N 0.000 description 1
- GEPDYQSQVLXLEU-AATRIKPKSA-N methyl (e)-3-dimethoxyphosphoryloxybut-2-enoate Chemical compound COC(=O)\C=C(/C)OP(=O)(OC)OC GEPDYQSQVLXLEU-AATRIKPKSA-N 0.000 description 1
- KBHDSWIXRODKSZ-UHFFFAOYSA-N methyl 5-chloro-2-(trifluoromethylsulfonylamino)benzoate Chemical compound COC(=O)C1=CC(Cl)=CC=C1NS(=O)(=O)C(F)(F)F KBHDSWIXRODKSZ-UHFFFAOYSA-N 0.000 description 1
- CJPQIRJHIZUAQP-UHFFFAOYSA-N methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)alaninate Chemical compound CC=1C=CC=C(C)C=1N(C(C)C(=O)OC)C(=O)CC1=CC=CC=C1 CJPQIRJHIZUAQP-UHFFFAOYSA-N 0.000 description 1
- LZUDDIQLMGVFAA-UHFFFAOYSA-N methyl N-[2-[(1,4-dimethyl-5-phenylpyrazol-3-yl)oxymethyl]phenyl]-N-methoxycarbamate Chemical compound COC(N(OC)C1=C(C=CC=C1)COC1=NN(C(=C1C)C1=CC=CC=C1)C)=O LZUDDIQLMGVFAA-UHFFFAOYSA-N 0.000 description 1
- 229940102396 methyl bromide Drugs 0.000 description 1
- NJQMOZPWNXUSIL-UHFFFAOYSA-N methyl n-[[3,5-dibromo-2-[[5-bromo-2-(3-chloropyridin-2-yl)pyrazole-3-carbonyl]amino]benzoyl]-methylamino]-n-methylcarbamate Chemical compound COC(=O)N(C)N(C)C(=O)C1=CC(Br)=CC(Br)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl NJQMOZPWNXUSIL-UHFFFAOYSA-N 0.000 description 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 description 1
- VOEYXMAFNDNNED-UHFFFAOYSA-N metolcarb Chemical compound CNC(=O)OC1=CC=CC(C)=C1 VOEYXMAFNDNNED-UHFFFAOYSA-N 0.000 description 1
- 229960001952 metrifonate Drugs 0.000 description 1
- XUQQRGKFXLAPNV-UHFFFAOYSA-N metyltetraprole Chemical compound CC1=CC=CC(N2C(N(C)N=N2)=O)=C1COC(=N1)C=CN1C1=CC=C(Cl)C=C1 XUQQRGKFXLAPNV-UHFFFAOYSA-N 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 description 1
- KCIRYJNISRMYFI-UHFFFAOYSA-N mildiomycin Natural products NC(CO)C(=O)NC1C=CC(OC1C(O)(CC(O)CNC(=N)N)C(=O)O)N2CN=C(N)C(=C2)CO KCIRYJNISRMYFI-UHFFFAOYSA-N 0.000 description 1
- KRTSDMXIXPKRQR-AATRIKPKSA-N monocrotophos Chemical compound CNC(=O)\C=C(/C)OP(=O)(OC)OC KRTSDMXIXPKRQR-AATRIKPKSA-N 0.000 description 1
- 235000010460 mustard Nutrition 0.000 description 1
- GIPNVQZZSSKOQF-UHFFFAOYSA-N n'-(2,5-dimethyl-4-phenoxyphenyl)-n-ethyl-n-methylmethanimidamide Chemical compound C1=C(C)C(N=CN(C)CC)=CC(C)=C1OC1=CC=CC=C1 GIPNVQZZSSKOQF-UHFFFAOYSA-N 0.000 description 1
- RXFQELGMJUSBGP-UHFFFAOYSA-N n'-[4-[4-chloro-3-(trifluoromethyl)phenoxy]-2,5-dimethylphenyl]-n-ethyl-n-methylmethanimidamide Chemical compound C1=C(C)C(N=CN(C)CC)=CC(C)=C1OC1=CC=C(Cl)C(C(F)(F)F)=C1 RXFQELGMJUSBGP-UHFFFAOYSA-N 0.000 description 1
- PAGDTTPJSICKIZ-UHFFFAOYSA-N n'-[4-[[3-[(4-chlorophenyl)methyl]-1,2,4-thiadiazol-5-yl]oxy]-2,5-dimethylphenyl]-n-ethyl-n-methylmethanimidamide Chemical compound C1=C(C)C(N=CN(C)CC)=CC(C)=C1OC1=NC(CC=2C=CC(Cl)=CC=2)=NS1 PAGDTTPJSICKIZ-UHFFFAOYSA-N 0.000 description 1
- SURYGMYUVAMSRO-UHFFFAOYSA-N n'-[5-(difluoromethyl)-2-methyl-4-(3-trimethylsilylpropoxy)phenyl]-n-ethyl-n-methylmethanimidamide Chemical compound CCN(C)C=NC1=CC(C(F)F)=C(OCCC[Si](C)(C)C)C=C1C SURYGMYUVAMSRO-UHFFFAOYSA-N 0.000 description 1
- XMSYZKCBUKZYIU-UHFFFAOYSA-N n'-[5-bromo-2-methyl-6-(4-propan-2-ylcyclohexyl)oxypyridin-3-yl]-n-ethyl-n-methylmethanimidamide Chemical compound N1=C(C)C(N=CN(C)CC)=CC(Br)=C1OC1CCC(C(C)C)CC1 XMSYZKCBUKZYIU-UHFFFAOYSA-N 0.000 description 1
- QPWDBFQQYNCENC-UHFFFAOYSA-N n'-[5-bromo-6-(2,3-dihydro-1h-inden-2-yloxy)-2-methylpyridin-3-yl]-n-ethyl-n-methylmethanimidamide Chemical compound N1=C(C)C(N=CN(C)CC)=CC(Br)=C1OC1CC2=CC=CC=C2C1 QPWDBFQQYNCENC-UHFFFAOYSA-N 0.000 description 1
- QUBHBTSVQMARKX-UHFFFAOYSA-N n'-[5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl]-n-ethyl-n-methylmethanimidamide Chemical compound N1=C(C)C(N=CN(C)CC)=CC(Br)=C1OC(C)C1=CC(F)=CC(F)=C1 QUBHBTSVQMARKX-UHFFFAOYSA-N 0.000 description 1
- TUCSJFNYZJYLHE-UHFFFAOYSA-N n'-tert-butyl-n'-(3,5-dimethylbenzoyl)-2,7-dimethyl-2,3-dihydro-1-benzofuran-6-carbohydrazide Chemical compound CC1=C2OC(C)CC2=CC=C1C(=O)NN(C(C)(C)C)C(=O)C1=CC(C)=CC(C)=C1 TUCSJFNYZJYLHE-UHFFFAOYSA-N 0.000 description 1
- XDRDPGIDCNALCL-UHFFFAOYSA-N n,5-dimethyl-1-propan-2-yl-n-pyridazin-4-ylpyrazole-4-carboxamide Chemical compound CC(C)N1N=CC(C(=O)N(C)C=2C=NN=CC=2)=C1C XDRDPGIDCNALCL-UHFFFAOYSA-N 0.000 description 1
- CSEZGNNRHRGCMT-UHFFFAOYSA-N n-(3-chloro-1-pyridin-3-ylpyrazol-4-yl)-3-[(2,2-difluorocyclopropyl)methylsulfanyl]-n-ethylpropanamide Chemical compound C=1N(C=2C=NC=CC=2)N=C(Cl)C=1N(CC)C(=O)CCSCC1CC1(F)F CSEZGNNRHRGCMT-UHFFFAOYSA-N 0.000 description 1
- YEOYRODOIOPWQG-UHFFFAOYSA-N n-(3-chloro-1-pyridin-3-ylpyrazol-4-yl)-3-[(2,2-difluorocyclopropyl)methylsulfinyl]-n-ethylpropanamide Chemical compound C=1N(C=2C=NC=CC=2)N=C(Cl)C=1N(CC)C(=O)CCS(=O)CC1CC1(F)F YEOYRODOIOPWQG-UHFFFAOYSA-N 0.000 description 1
- BUTXJHNFXHLCIM-UHFFFAOYSA-N n-(3-chloro-1-pyridin-3-ylpyrazol-4-yl)-n-ethyl-3-(3,3,3-trifluoropropylsulfinyl)propanamide Chemical compound N1=C(Cl)C(N(C(=O)CCS(=O)CCC(F)(F)F)CC)=CN1C1=CC=CN=C1 BUTXJHNFXHLCIM-UHFFFAOYSA-N 0.000 description 1
- UDZVDQGVXXFQJI-UHFFFAOYSA-N n-[1-[(6-chloropyridin-3-yl)methyl]pyridin-2-ylidene]-2,2,2-trifluoro-n'-propan-2-ylethanimidamide Chemical compound CC(C)N=C(C(F)(F)F)N=C1C=CC=CN1CC1=CC=C(Cl)N=C1 UDZVDQGVXXFQJI-UHFFFAOYSA-N 0.000 description 1
- CRNGSNQWDMIZKH-UHFFFAOYSA-N n-[1-[(6-chloropyridin-3-yl)methyl]pyridin-2-ylidene]-2,2,2-trifluoroethanethioamide Chemical compound FC(F)(F)C(=S)N=C1C=CC=CN1CC1=CC=C(Cl)N=C1 CRNGSNQWDMIZKH-UHFFFAOYSA-N 0.000 description 1
- QATGFSXETMWYGK-UHFFFAOYSA-N n-[2-bromo-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl]-2-fluoro-3-[(4-fluorobenzoyl)-methylamino]benzamide Chemical compound C=1C=CC(C(=O)NC=2C(=CC(=CC=2Br)C(F)(C(F)(F)F)C(F)(F)F)C(F)(F)F)=C(F)C=1N(C)C(=O)C1=CC=C(F)C=C1 QATGFSXETMWYGK-UHFFFAOYSA-N 0.000 description 1
- TWBPBBYSUHJSBT-UHFFFAOYSA-N n-[5-[[2-bromo-6-chloro-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]carbamoyl]-2-cyanophenyl]-4-cyano-2-methylbenzamide Chemical compound CC1=CC(C#N)=CC=C1C(=O)NC1=CC(C(=O)NC=2C(=CC(=CC=2Cl)C(F)(C(F)(F)F)C(F)(F)F)Br)=CC=C1C#N TWBPBBYSUHJSBT-UHFFFAOYSA-N 0.000 description 1
- NXCYXIXOZZSUII-UHFFFAOYSA-N n-[5-[[2-bromo-6-chloro-4-(1,1,1,2,3,3,4,4,4-nonafluorobutan-2-yl)phenyl]carbamoyl]-2-cyanophenyl]-4-cyano-2-methylbenzamide Chemical compound CC1=CC(C#N)=CC=C1C(=O)NC1=CC(C(=O)NC=2C(=CC(=CC=2Cl)C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)Br)=CC=C1C#N NXCYXIXOZZSUII-UHFFFAOYSA-N 0.000 description 1
- PJDSTFBZLDPIQR-UHFFFAOYSA-N n-[5-[[2-bromo-6-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]carbamoyl]-2-cyanophenyl]-4-cyano-2-methylbenzamide Chemical compound CC1=CC(C#N)=CC=C1C(=O)NC1=CC(C(=O)NC=2C(=CC(=CC=2Cl)C(O)(C(F)(F)F)C(F)(F)F)Br)=CC=C1C#N PJDSTFBZLDPIQR-UHFFFAOYSA-N 0.000 description 1
- SCYMJHWKBOKMOQ-UHFFFAOYSA-N n-[5-[[2-chloro-6-cyano-4-(1,1,1,2,3,3,4,4,4-nonafluorobutan-2-yl)phenyl]carbamoyl]-2-cyanophenyl]-4-cyano-2-methylbenzamide Chemical compound CC1=CC(C#N)=CC=C1C(=O)NC1=CC(C(=O)NC=2C(=CC(=CC=2Cl)C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)C#N)=CC=C1C#N SCYMJHWKBOKMOQ-UHFFFAOYSA-N 0.000 description 1
- YNKFZRGTXAPYFD-UHFFFAOYSA-N n-[[2-chloro-3,5-bis(trifluoromethyl)phenyl]carbamoyl]-2,6-difluorobenzamide Chemical compound FC1=CC=CC(F)=C1C(=O)NC(=O)NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1Cl YNKFZRGTXAPYFD-UHFFFAOYSA-N 0.000 description 1
- FPBPNKLWFXIJCZ-UHFFFAOYSA-N n-ethyl-2-(3-ethynyl-8-methylquinolin-6-yl)oxybutanamide Chemical compound N1=CC(C#C)=CC2=CC(OC(CC)C(=O)NCC)=CC(C)=C21 FPBPNKLWFXIJCZ-UHFFFAOYSA-N 0.000 description 1
- NQPGZXOPMRKAGJ-UHFFFAOYSA-N n-ethyl-5-methyl-1-(3-methylbutan-2-yl)-n-pyridazin-4-ylpyrazole-4-carboxamide Chemical compound C=1C=NN=CC=1N(CC)C(=O)C=1C=NN(C(C)C(C)C)C=1C NQPGZXOPMRKAGJ-UHFFFAOYSA-N 0.000 description 1
- OKQXFDSPKIACRT-UHFFFAOYSA-N n-ethyl-n'-[4-[4-fluoro-3-(trifluoromethyl)phenoxy]-2,5-dimethylphenyl]-n-methylmethanimidamide Chemical compound C1=C(C)C(N=CN(C)CC)=CC(C)=C1OC1=CC=C(F)C(C(F)(F)F)=C1 OKQXFDSPKIACRT-UHFFFAOYSA-N 0.000 description 1
- SACHJKZWHBFWEL-UHFFFAOYSA-N n-ethyl-n-methyl-n'-[2-methyl-5-(trifluoromethyl)-4-(3-trimethylsilylpropoxy)phenyl]methanimidamide Chemical compound CCN(C)C=NC1=CC(C(F)(F)F)=C(OCCC[Si](C)(C)C)C=C1C SACHJKZWHBFWEL-UHFFFAOYSA-N 0.000 description 1
- FCDOWQOIVVEOJB-UHFFFAOYSA-N n-propan-2-yl-2-pyridin-3-ylindazole-4-carboxamide Chemical compound C1=C2C(C(=O)NC(C)C)=CC=CC2=NN1C1=CC=CN=C1 FCDOWQOIVVEOJB-UHFFFAOYSA-N 0.000 description 1
- BUYMVQAILCEWRR-UHFFFAOYSA-N naled Chemical compound COP(=O)(OC)OC(Br)C(Cl)(Cl)Br BUYMVQAILCEWRR-UHFFFAOYSA-N 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- DSOOGBGKEWZRIH-UHFFFAOYSA-N nereistoxin Chemical class CN(C)C1CSSC1 DSOOGBGKEWZRIH-UHFFFAOYSA-N 0.000 description 1
- 229960002715 nicotine Drugs 0.000 description 1
- 229940079888 nitenpyram Drugs 0.000 description 1
- DCUJJWWUNKIJPH-UHFFFAOYSA-N nitrapyrin Chemical compound ClC1=CC=CC(C(Cl)(Cl)Cl)=N1 DCUJJWWUNKIJPH-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 125000006501 nitrophenyl group Chemical group 0.000 description 1
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 1
- YTYGAJLZOJPJGH-UHFFFAOYSA-N noviflumuron Chemical compound FC1=C(Cl)C(OC(F)(F)C(C(F)(F)F)F)=C(Cl)C=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F YTYGAJLZOJPJGH-UHFFFAOYSA-N 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- QHGUCRYDKWKLMG-UHFFFAOYSA-N octopamine Chemical compound NCC(O)C1=CC=C(O)C=C1 QHGUCRYDKWKLMG-UHFFFAOYSA-N 0.000 description 1
- PZXOQEXFMJCDPG-UHFFFAOYSA-N omethoate Chemical compound CNC(=O)CSP(=O)(OC)OC PZXOQEXFMJCDPG-UHFFFAOYSA-N 0.000 description 1
- JHIPUJPTQJYEQK-ZLHHXESBSA-N orysastrobin Chemical compound CNC(=O)C(=N\OC)\C1=CC=CC=C1CO\N=C(/C)\C(=N\OC)\C(\C)=N\OC JHIPUJPTQJYEQK-ZLHHXESBSA-N 0.000 description 1
- UWVQIROCRJWDKL-UHFFFAOYSA-N oxadixyl Chemical compound CC=1C=CC=C(C)C=1N(C(=O)COC)N1CCOC1=O UWVQIROCRJWDKL-UHFFFAOYSA-N 0.000 description 1
- KZAUOCCYDRDERY-UHFFFAOYSA-N oxamyl Chemical compound CNC(=O)ON=C(SC)C(=O)N(C)C KZAUOCCYDRDERY-UHFFFAOYSA-N 0.000 description 1
- 229960000321 oxolinic acid Drugs 0.000 description 1
- AMEKQAFGQBKLKX-UHFFFAOYSA-N oxycarboxin Chemical compound O=S1(=O)CCOC(C)=C1C(=O)NC1=CC=CC=C1 AMEKQAFGQBKLKX-UHFFFAOYSA-N 0.000 description 1
- PMCVMORKVPSKHZ-UHFFFAOYSA-N oxydemeton-methyl Chemical compound CCS(=O)CCSP(=O)(OC)OC PMCVMORKVPSKHZ-UHFFFAOYSA-N 0.000 description 1
- 102000044160 oxysterol binding protein Human genes 0.000 description 1
- 108010040421 oxysterol binding protein Proteins 0.000 description 1
- IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 description 1
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 description 1
- LCCNCVORNKJIRZ-UHFFFAOYSA-N parathion Chemical compound CCOP(=S)(OCC)OC1=CC=C([N+]([O-])=O)C=C1 LCCNCVORNKJIRZ-UHFFFAOYSA-N 0.000 description 1
- RLBIQVVOMOPOHC-UHFFFAOYSA-N parathion-methyl Chemical group COP(=S)(OC)OC1=CC=C([N+]([O-])=O)C=C1 RLBIQVVOMOPOHC-UHFFFAOYSA-N 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- OGYFATSSENRIKG-UHFFFAOYSA-N pencycuron Chemical compound C1=CC(Cl)=CC=C1CN(C(=O)NC=1C=CC=CC=1)C1CCCC1 OGYFATSSENRIKG-UHFFFAOYSA-N 0.000 description 1
- WBTYBAGIHOISOQ-UHFFFAOYSA-N pent-4-en-1-yl 2-[(2-furylmethyl)(imidazol-1-ylcarbonyl)amino]butanoate Chemical compound C1=CN=CN1C(=O)N(C(CC)C(=O)OCCCC=C)CC1=CC=CO1 WBTYBAGIHOISOQ-UHFFFAOYSA-N 0.000 description 1
- LKPLKUMXSAEKID-UHFFFAOYSA-N pentachloronitrobenzene Chemical compound [O-][N+](=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl LKPLKUMXSAEKID-UHFFFAOYSA-N 0.000 description 1
- WPIFGDDVIKNHOC-PLRJNAJWSA-N pentyl n-[6-[[(z)-[(1-methyltetrazol-5-yl)-phenylmethylidene]amino]oxymethyl]pyridin-2-yl]carbamate Chemical compound CCCCCOC(=O)NC1=CC=CC(CO\N=C(/C=2N(N=NN=2)C)C=2C=CC=CC=2)=N1 WPIFGDDVIKNHOC-PLRJNAJWSA-N 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229960000490 permethrin Drugs 0.000 description 1
- RLLPVAHGXHCWKJ-UHFFFAOYSA-N permethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-UHFFFAOYSA-N 0.000 description 1
- 229960003536 phenothrin Drugs 0.000 description 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 description 1
- XAMUDJHXFNRLCY-UHFFFAOYSA-N phenthoate Chemical compound CCOC(=O)C(SP(=S)(OC)OC)C1=CC=CC=C1 XAMUDJHXFNRLCY-UHFFFAOYSA-N 0.000 description 1
- 150000008048 phenylpyrazoles Chemical class 0.000 description 1
- BULVZWIRKLYCBC-UHFFFAOYSA-N phorate Chemical compound CCOP(=S)(OCC)SCSCC BULVZWIRKLYCBC-UHFFFAOYSA-N 0.000 description 1
- IOUNQDKNJZEDEP-UHFFFAOYSA-N phosalone Chemical compound C1=C(Cl)C=C2OC(=O)N(CSP(=S)(OCC)OCC)C2=C1 IOUNQDKNJZEDEP-UHFFFAOYSA-N 0.000 description 1
- LMNZTLDVJIUSHT-UHFFFAOYSA-N phosmet Chemical compound C1=CC=C2C(=O)N(CSP(=S)(OC)OC)C(=O)C2=C1 LMNZTLDVJIUSHT-UHFFFAOYSA-N 0.000 description 1
- RGCLLPNLLBQHPF-HJWRWDBZSA-N phosphamidon Chemical compound CCN(CC)C(=O)C(\Cl)=C(/C)OP(=O)(OC)OC RGCLLPNLLBQHPF-HJWRWDBZSA-N 0.000 description 1
- HOKBIQDJCNTWST-UHFFFAOYSA-N phosphanylidenezinc;zinc Chemical compound [Zn].[Zn]=P.[Zn]=P HOKBIQDJCNTWST-UHFFFAOYSA-N 0.000 description 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 description 1
- ATROHALUCMTWTB-OWBHPGMISA-N phoxim Chemical compound CCOP(=S)(OCC)O\N=C(\C#N)C1=CC=CC=C1 ATROHALUCMTWTB-OWBHPGMISA-N 0.000 description 1
- 229950001664 phoxim Drugs 0.000 description 1
- 229940085127 phytase Drugs 0.000 description 1
- URHWNXDZOULUHC-ULJHMMPZSA-N picarbutrazox Chemical compound CN1N=NN=C1\C(C=1C=CC=CC=1)=N/OCC1=CC=CC(NC(=O)OC(C)(C)C)=N1 URHWNXDZOULUHC-ULJHMMPZSA-N 0.000 description 1
- 150000004885 piperazines Chemical class 0.000 description 1
- 229960005235 piperonyl butoxide Drugs 0.000 description 1
- YFGYUFNIOHWBOB-UHFFFAOYSA-N pirimicarb Chemical compound CN(C)C(=O)OC1=NC(N(C)C)=NC(C)=C1C YFGYUFNIOHWBOB-UHFFFAOYSA-N 0.000 description 1
- QHOQHJPRIBSPCY-UHFFFAOYSA-N pirimiphos-methyl Chemical group CCN(CC)C1=NC(C)=CC(OP(=S)(OC)OC)=N1 QHOQHJPRIBSPCY-UHFFFAOYSA-N 0.000 description 1
- 235000020233 pistachio Nutrition 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 239000005648 plant growth regulator Substances 0.000 description 1
- 235000021018 plums Nutrition 0.000 description 1
- YEBIHIICWDDQOL-YBHNRIQQSA-N polyoxin Polymers O[C@@H]1[C@H](O)[C@@H](C(C=O)N)O[C@H]1N1C(=O)NC(=O)C(C(O)=O)=C1 YEBIHIICWDDQOL-YBHNRIQQSA-N 0.000 description 1
- 235000021039 pomes Nutrition 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- SMKRKQBMYOFFMU-UHFFFAOYSA-N prallethrin Chemical compound CC1(C)C(C=C(C)C)C1C(=O)OC1C(C)=C(CC#C)C(=O)C1 SMKRKQBMYOFFMU-UHFFFAOYSA-N 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- WHHIPMZEDGBUCC-UHFFFAOYSA-N probenazole Chemical compound C1=CC=C2C(OCC=C)=NS(=O)(=O)C2=C1 WHHIPMZEDGBUCC-UHFFFAOYSA-N 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- QXJKBPAVAHBARF-BETUJISGSA-N procymidone Chemical compound O=C([C@]1(C)C[C@@]1(C1=O)C)N1C1=CC(Cl)=CC(Cl)=C1 QXJKBPAVAHBARF-BETUJISGSA-N 0.000 description 1
- QYMMJNLHFKGANY-UHFFFAOYSA-N profenofos Chemical compound CCCSP(=O)(OCC)OC1=CC=C(Br)C=C1Cl QYMMJNLHFKGANY-UHFFFAOYSA-N 0.000 description 1
- WZZLDXDUQPOXNW-UHFFFAOYSA-N propamocarb Chemical compound CCCOC(=O)NCCCN(C)C WZZLDXDUQPOXNW-UHFFFAOYSA-N 0.000 description 1
- ZYHMJXZULPZUED-UHFFFAOYSA-N propargite Chemical compound C1=CC(C(C)(C)C)=CC=C1OC1C(OS(=O)OCC#C)CCCC1 ZYHMJXZULPZUED-UHFFFAOYSA-N 0.000 description 1
- BZNDWPRGXNILMS-VQHVLOKHSA-N propetamphos Chemical compound CCNP(=S)(OC)O\C(C)=C\C(=O)OC(C)C BZNDWPRGXNILMS-VQHVLOKHSA-N 0.000 description 1
- STJLVHWMYQXCPB-UHFFFAOYSA-N propiconazole Chemical compound O1C(CCC)COC1(C=1C(=CC(Cl)=CC=1)Cl)CN1N=CN=C1 STJLVHWMYQXCPB-UHFFFAOYSA-N 0.000 description 1
- KKMLIVYBGSAJPM-UHFFFAOYSA-L propineb Chemical compound [Zn+2].[S-]C(=S)NC(C)CNC([S-])=S KKMLIVYBGSAJPM-UHFFFAOYSA-L 0.000 description 1
- 125000002572 propoxy group Chemical group [*]OC([H])([H])C(C([H])([H])[H])([H])[H] 0.000 description 1
- 239000012268 protein inhibitor Substances 0.000 description 1
- 229940121649 protein inhibitor Drugs 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 239000000007 protein synthesis inhibitor Substances 0.000 description 1
- FITIWKDOCAUBQD-UHFFFAOYSA-N prothiofos Chemical compound CCCSP(=S)(OCC)OC1=CC=C(Cl)C=C1Cl FITIWKDOCAUBQD-UHFFFAOYSA-N 0.000 description 1
- DZVWKNFPXMUIFA-UHFFFAOYSA-N pyflubumide Chemical compound C1=C(CC(C)C)C(C(OC)(C(F)(F)F)C(F)(F)F)=CC=C1N(C(=O)C(C)C)C(=O)C1=C(C)N(C)N=C1C DZVWKNFPXMUIFA-UHFFFAOYSA-N 0.000 description 1
- QHGVXILFMXYDRS-UHFFFAOYSA-N pyraclofos Chemical compound C1=C(OP(=O)(OCC)SCCC)C=NN1C1=CC=C(Cl)C=C1 QHGVXILFMXYDRS-UHFFFAOYSA-N 0.000 description 1
- DDIQWGKUSJOETH-UHFFFAOYSA-N pyrafluprole Chemical compound ClC=1C=C(C(F)(F)F)C=C(Cl)C=1N1N=C(C#N)C(SCF)=C1NCC1=CN=CC=N1 DDIQWGKUSJOETH-UHFFFAOYSA-N 0.000 description 1
- DWTVBEZBWMDXIY-UHFFFAOYSA-N pyrametostrobin Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=C(C)C(C=2C=CC=CC=2)=NN1C DWTVBEZBWMDXIY-UHFFFAOYSA-N 0.000 description 1
- URXNNPCNKVAQRA-XMHGGMMESA-N pyraoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1COC1=CC(C=2C=CC(Cl)=CC=2)=NN1C URXNNPCNKVAQRA-XMHGGMMESA-N 0.000 description 1
- JOOMJVFZQRQWKR-UHFFFAOYSA-N pyrazophos Chemical compound N1=C(C)C(C(=O)OCC)=CN2N=C(OP(=S)(OCC)OCC)C=C21 JOOMJVFZQRQWKR-UHFFFAOYSA-N 0.000 description 1
- HYJYGLGUBUDSLJ-UHFFFAOYSA-N pyrethrin Natural products CCC(=O)OC1CC(=C)C2CC3OC3(C)C2C2OC(=O)C(=C)C12 HYJYGLGUBUDSLJ-UHFFFAOYSA-N 0.000 description 1
- VJFUPGQZSXIULQ-XIGJTORUSA-N pyrethrin II Chemical compound CC1(C)[C@H](/C=C(\C)C(=O)OC)[C@H]1C(=O)O[C@@H]1C(C)=C(C\C=C/C=C)C(=O)C1 VJFUPGQZSXIULQ-XIGJTORUSA-N 0.000 description 1
- 229940015367 pyrethrum Drugs 0.000 description 1
- CRFYLQMIDWBKRT-LPYMAVHISA-N pyribencarb Chemical compound C1=C(Cl)C(CNC(=O)OC)=CC(C(\C)=N\OCC=2N=C(C)C=CC=2)=C1 CRFYLQMIDWBKRT-LPYMAVHISA-N 0.000 description 1
- DWFZBUWUXWZWKD-UHFFFAOYSA-N pyridaben Chemical compound C1=CC(C(C)(C)C)=CC=C1CSC1=C(Cl)C(=O)N(C(C)(C)C)N=C1 DWFZBUWUXWZWKD-UHFFFAOYSA-N 0.000 description 1
- AEHJMNVBLRLZKK-UHFFFAOYSA-N pyridalyl Chemical group N1=CC(C(F)(F)F)=CC=C1OCCCOC1=C(Cl)C=C(OCC=C(Cl)Cl)C=C1Cl AEHJMNVBLRLZKK-UHFFFAOYSA-N 0.000 description 1
- CXJSOEPQXUCJSA-UHFFFAOYSA-N pyridaphenthion Chemical compound N1=C(OP(=S)(OCC)OCC)C=CC(=O)N1C1=CC=CC=C1 CXJSOEPQXUCJSA-UHFFFAOYSA-N 0.000 description 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 1
- 150000003222 pyridines Chemical class 0.000 description 1
- ITKAIUGKVKDENI-UHFFFAOYSA-N pyrimidifen Chemical compound CC1=C(C)C(CCOCC)=CC=C1OCCNC1=NC=NC(CC)=C1Cl ITKAIUGKVKDENI-UHFFFAOYSA-N 0.000 description 1
- OYRRZWATULMEPF-UHFFFAOYSA-N pyrimidin-4-amine Chemical compound NC1=CC=NC=N1 OYRRZWATULMEPF-UHFFFAOYSA-N 0.000 description 1
- 150000003230 pyrimidines Chemical class 0.000 description 1
- YYXSCUSVVALMNW-FOWTUZBSSA-N pyriminostrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1COC1=CC(C(F)(F)F)=NC(NC=2C(=CC(Cl)=CC=2)Cl)=N1 YYXSCUSVVALMNW-FOWTUZBSSA-N 0.000 description 1
- BAUQXSYUDSNRHL-UHFFFAOYSA-N pyrimorph Chemical compound C1=CC(C(C)(C)C)=CC=C1C(C=1C=NC(Cl)=CC=1)=CC(=O)N1CCOCC1 BAUQXSYUDSNRHL-UHFFFAOYSA-N 0.000 description 1
- NMVCBWZLCXANER-UHFFFAOYSA-N pyriofenone Chemical compound COC1=C(OC)C(OC)=CC(C)=C1C(=O)C1=C(C)C(Cl)=CN=C1OC NMVCBWZLCXANER-UHFFFAOYSA-N 0.000 description 1
- NHDHVHZZCFYRSB-UHFFFAOYSA-N pyriproxyfen Chemical compound C=1C=CC=NC=1OC(C)COC(C=C1)=CC=C1OC1=CC=CC=C1 NHDHVHZZCFYRSB-UHFFFAOYSA-N 0.000 description 1
- DHTJFQWHCVTNRY-OEMAIJDKSA-N pyrisoxazole Chemical compound C1([C@@]2(C)CC(ON2C)C=2C=CC(Cl)=CC=2)=CC=CN=C1 DHTJFQWHCVTNRY-OEMAIJDKSA-N 0.000 description 1
- XRJLAOUDSILTFT-UHFFFAOYSA-N pyroquilon Chemical compound O=C1CCC2=CC=CC3=C2N1CC3 XRJLAOUDSILTFT-UHFFFAOYSA-N 0.000 description 1
- JYQUHIFYBATCCY-UHFFFAOYSA-N quinalphos Chemical compound C1=CC=CC2=NC(OP(=S)(OCC)OCC)=CN=C21 JYQUHIFYBATCCY-UHFFFAOYSA-N 0.000 description 1
- FBQQHUGEACOBDN-UHFFFAOYSA-N quinomethionate Chemical compound N1=C2SC(=O)SC2=NC2=CC(C)=CC=C21 FBQQHUGEACOBDN-UHFFFAOYSA-N 0.000 description 1
- WRPIRSINYZBGPK-UHFFFAOYSA-N quinoxyfen Chemical compound C1=CC(F)=CC=C1OC1=CC=NC2=CC(Cl)=CC(Cl)=C12 WRPIRSINYZBGPK-UHFFFAOYSA-N 0.000 description 1
- 235000021013 raspberries Nutrition 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 229940108410 resmethrin Drugs 0.000 description 1
- VEMKTZHHVJILDY-FIWHBWSRSA-N resmethrin Chemical compound CC1(C)[C@H](C=C(C)C)C1C(=O)OCC1=COC(CC=2C=CC=CC=2)=C1 VEMKTZHHVJILDY-FIWHBWSRSA-N 0.000 description 1
- 230000012865 response to insecticide Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 229940080817 rotenone Drugs 0.000 description 1
- JUVIOZPCNVVQFO-UHFFFAOYSA-N rotenone Natural products O1C2=C3CC(C(C)=C)OC3=CC=C2C(=O)C2C1COC1=C2C=C(OC)C(OC)=C1 JUVIOZPCNVVQFO-UHFFFAOYSA-N 0.000 description 1
- MSHXTAQSSIEBQS-UHFFFAOYSA-N s-[3-carbamoylsulfanyl-2-(dimethylamino)propyl] carbamothioate;hydron;chloride Chemical compound [Cl-].NC(=O)SCC([NH+](C)C)CSC(N)=O MSHXTAQSSIEBQS-UHFFFAOYSA-N 0.000 description 1
- 229960005393 sarolaner Drugs 0.000 description 1
- 239000003620 semiochemical Substances 0.000 description 1
- 238000009366 sericulture Methods 0.000 description 1
- 230000019491 signal transduction Effects 0.000 description 1
- HPYNBECUCCGGPA-UHFFFAOYSA-N silafluofen Chemical compound C1=CC(OCC)=CC=C1[Si](C)(C)CCCC1=CC=C(F)C(OC=2C=CC=CC=2)=C1 HPYNBECUCCGGPA-UHFFFAOYSA-N 0.000 description 1
- MXMXHPPIGKYTAR-UHFFFAOYSA-N silthiofam Chemical compound CC=1SC([Si](C)(C)C)=C(C(=O)NCC=C)C=1C MXMXHPPIGKYTAR-UHFFFAOYSA-N 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000004328 sodium tetraborate Substances 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 229930185156 spinosyn Natural products 0.000 description 1
- PUYXTUJWRLOUCW-UHFFFAOYSA-N spiroxamine Chemical compound O1C(CN(CC)CCC)COC11CCC(C(C)(C)C)CC1 PUYXTUJWRLOUCW-UHFFFAOYSA-N 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 235000021012 strawberries Nutrition 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- CCEKAJIANROZEO-UHFFFAOYSA-N sulfluramid Chemical compound CCNS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F CCEKAJIANROZEO-UHFFFAOYSA-N 0.000 description 1
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 description 1
- XIUROWKZWPIAIB-UHFFFAOYSA-N sulfotep Chemical compound CCOP(=S)(OCC)OP(=S)(OCC)OCC XIUROWKZWPIAIB-UHFFFAOYSA-N 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- OBTWBSRJZRCYQV-UHFFFAOYSA-N sulfuryl difluoride Chemical compound FS(F)(=O)=O OBTWBSRJZRCYQV-UHFFFAOYSA-N 0.000 description 1
- 239000005936 tau-Fluvalinate Substances 0.000 description 1
- INISTDXBRIBGOC-XMMISQBUSA-N tau-fluvalinate Chemical compound N([C@H](C(C)C)C(=O)OC(C#N)C=1C=C(OC=2C=CC=CC=2)C=CC=1)C1=CC=C(C(F)(F)F)C=C1Cl INISTDXBRIBGOC-XMMISQBUSA-N 0.000 description 1
- QYPNKSZPJQQLRK-UHFFFAOYSA-N tebufenozide Chemical compound C1=CC(CC)=CC=C1C(=O)NN(C(C)(C)C)C(=O)C1=CC(C)=CC(C)=C1 QYPNKSZPJQQLRK-UHFFFAOYSA-N 0.000 description 1
- ZZYSLNWGKKDOML-UHFFFAOYSA-N tebufenpyrad Chemical compound CCC1=NN(C)C(C(=O)NCC=2C=CC(=CC=2)C(C)(C)C)=C1Cl ZZYSLNWGKKDOML-UHFFFAOYSA-N 0.000 description 1
- LWLJEQHTPVPKSJ-UHFFFAOYSA-N tebufloquin Chemical compound C1=C(C(C)(C)C)C=C2C(OC(=O)C)=C(C)C(C)=NC2=C1F LWLJEQHTPVPKSJ-UHFFFAOYSA-N 0.000 description 1
- AWYOMXWDGWUJHS-UHFFFAOYSA-N tebupirimfos Chemical compound CCOP(=S)(OC(C)C)OC1=CN=C(C(C)(C)C)N=C1 AWYOMXWDGWUJHS-UHFFFAOYSA-N 0.000 description 1
- XQTLDIFVVHJORV-UHFFFAOYSA-N tecnazene Chemical compound [O-][N+](=O)C1=C(Cl)C(Cl)=CC(Cl)=C1Cl XQTLDIFVVHJORV-UHFFFAOYSA-N 0.000 description 1
- CJDWRQLODFKPEL-UHFFFAOYSA-N teflubenzuron Chemical compound FC1=CC=CC(F)=C1C(=O)NC(=O)NC1=CC(Cl)=C(F)C(Cl)=C1F CJDWRQLODFKPEL-UHFFFAOYSA-N 0.000 description 1
- WWJZWCUNLNYYAU-UHFFFAOYSA-N temephos Chemical compound C1=CC(OP(=S)(OC)OC)=CC=C1SC1=CC=C(OP(=S)(OC)OC)C=C1 WWJZWCUNLNYYAU-UHFFFAOYSA-N 0.000 description 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
- ISIJQEHRDSCQIU-UHFFFAOYSA-N tert-butyl 2,7-diazaspiro[4.5]decane-7-carboxylate Chemical compound C1N(C(=O)OC(C)(C)C)CCCC11CNCC1 ISIJQEHRDSCQIU-UHFFFAOYSA-N 0.000 description 1
- UBCKGWBNUIFUST-YHYXMXQVSA-N tetrachlorvinphos Chemical compound COP(=O)(OC)O\C(=C/Cl)C1=CC(Cl)=C(Cl)C=C1Cl UBCKGWBNUIFUST-YHYXMXQVSA-N 0.000 description 1
- LITQZINTSYBKIU-UHFFFAOYSA-F tetracopper;hexahydroxide;sulfate Chemical compound [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[Cu+2].[Cu+2].[Cu+2].[Cu+2].[O-]S([O-])(=O)=O LITQZINTSYBKIU-UHFFFAOYSA-F 0.000 description 1
- MLGCXEBRWGEOQX-UHFFFAOYSA-N tetradifon Chemical compound C1=CC(Cl)=CC=C1S(=O)(=O)C1=CC(Cl)=C(Cl)C=C1Cl MLGCXEBRWGEOQX-UHFFFAOYSA-N 0.000 description 1
- 229960005199 tetramethrin Drugs 0.000 description 1
- 239000004308 thiabendazole Substances 0.000 description 1
- 235000010296 thiabendazole Nutrition 0.000 description 1
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 description 1
- 229960004546 thiabendazole Drugs 0.000 description 1
- 125000004496 thiazol-5-yl group Chemical group S1C=NC=C1* 0.000 description 1
- WOSNCVAPUOFXEH-UHFFFAOYSA-N thifluzamide Chemical compound S1C(C)=NC(C(F)(F)F)=C1C(=O)NC1=C(Br)C=C(OC(F)(F)F)C=C1Br WOSNCVAPUOFXEH-UHFFFAOYSA-N 0.000 description 1
- 150000003558 thiocarbamic acid derivatives Chemical class 0.000 description 1
- DNVLJEWNNDHELH-UHFFFAOYSA-N thiocyclam Chemical compound CN(C)C1CSSSC1 DNVLJEWNNDHELH-UHFFFAOYSA-N 0.000 description 1
- BAKXBZPQTXCKRR-UHFFFAOYSA-N thiodicarb Chemical compound CSC(C)=NOC(=O)NSNC(=O)ON=C(C)SC BAKXBZPQTXCKRR-UHFFFAOYSA-N 0.000 description 1
- OPASCBHCTNRLRM-UHFFFAOYSA-N thiometon Chemical compound CCSCCSP(=S)(OC)OC OPASCBHCTNRLRM-UHFFFAOYSA-N 0.000 description 1
- QSOHVSNIQHGFJU-UHFFFAOYSA-L thiosultap disodium Chemical compound [Na+].[Na+].[O-]S(=O)(=O)SCC(N(C)C)CSS([O-])(=O)=O QSOHVSNIQHGFJU-UHFFFAOYSA-L 0.000 description 1
- VJQYLJSMBWXGDV-UHFFFAOYSA-N tiadinil Chemical compound N1=NSC(C(=O)NC=2C=C(Cl)C(C)=CC=2)=C1C VJQYLJSMBWXGDV-UHFFFAOYSA-N 0.000 description 1
- IHNSIFFSNUQGQN-UHFFFAOYSA-N tioxazafen Chemical compound C1=CSC(C=2ON=C(N=2)C=2C=CC=CC=2)=C1 IHNSIFFSNUQGQN-UHFFFAOYSA-N 0.000 description 1
- OBZIQQJJIKNWNO-UHFFFAOYSA-N tolclofos-methyl Chemical compound COP(=S)(OC)OC1=C(Cl)C=C(C)C=C1Cl OBZIQQJJIKNWNO-UHFFFAOYSA-N 0.000 description 1
- WPALTCMYPARVNV-UHFFFAOYSA-N tolfenpyrad Chemical compound CCC1=NN(C)C(C(=O)NCC=2C=CC(OC=3C=CC(C)=CC=3)=CC=2)=C1Cl WPALTCMYPARVNV-UHFFFAOYSA-N 0.000 description 1
- RSOBJVBYZCMJOS-CYBMUJFWSA-N tolprocarb Chemical compound FC(F)(F)COC(=O)N[C@@H](C(C)C)CNC(=O)C1=CC=C(C)C=C1 RSOBJVBYZCMJOS-CYBMUJFWSA-N 0.000 description 1
- HYVWIQDYBVKITD-UHFFFAOYSA-N tolylfluanid Chemical compound CN(C)S(=O)(=O)N(SC(F)(Cl)Cl)C1=CC=C(C)C=C1 HYVWIQDYBVKITD-UHFFFAOYSA-N 0.000 description 1
- YWSCPYYRJXKUDB-KAKFPZCNSA-N tralomethrin Chemical compound CC1(C)[C@@H](C(Br)C(Br)(Br)Br)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 YWSCPYYRJXKUDB-KAKFPZCNSA-N 0.000 description 1
- DDVNRFNDOPPVQJ-HQJQHLMTSA-N transfluthrin Chemical compound CC1(C)[C@H](C=C(Cl)Cl)[C@H]1C(=O)OCC1=C(F)C(F)=CC(F)=C1F DDVNRFNDOPPVQJ-HQJQHLMTSA-N 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- BAZVSMNPJJMILC-UHFFFAOYSA-N triadimenol Chemical compound C1=NC=NN1C(C(O)C(C)(C)C)OC1=CC=C(Cl)C=C1 BAZVSMNPJJMILC-UHFFFAOYSA-N 0.000 description 1
- NKNFWVNSBIXGLL-UHFFFAOYSA-N triazamate Chemical compound CCOC(=O)CSC1=NC(C(C)(C)C)=NN1C(=O)N(C)C NKNFWVNSBIXGLL-UHFFFAOYSA-N 0.000 description 1
- 150000003852 triazoles Chemical class 0.000 description 1
- AMFGTOFWMRQMEM-UHFFFAOYSA-N triazophos Chemical compound N1=C(OP(=S)(OCC)OCC)N=CN1C1=CC=CC=C1 AMFGTOFWMRQMEM-UHFFFAOYSA-N 0.000 description 1
- IQGKIPDJXCAMSM-UHFFFAOYSA-N triazoxide Chemical compound N=1C2=CC=C(Cl)C=C2[N+]([O-])=NC=1N1C=CN=C1 IQGKIPDJXCAMSM-UHFFFAOYSA-N 0.000 description 1
- 229940096911 trichinella spiralis Drugs 0.000 description 1
- NFACJZMKEDPNKN-UHFFFAOYSA-N trichlorfon Chemical compound COP(=O)(OC)C(O)C(Cl)(Cl)Cl NFACJZMKEDPNKN-UHFFFAOYSA-N 0.000 description 1
- QFNFRZHOXWNWAQ-UHFFFAOYSA-N triclopyricarb Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=NC(Cl)=C(Cl)C=C1Cl QFNFRZHOXWNWAQ-UHFFFAOYSA-N 0.000 description 1
- DQJCHOQLCLEDLL-UHFFFAOYSA-N tricyclazole Chemical compound CC1=CC=CC2=C1N1C=NN=C1S2 DQJCHOQLCLEDLL-UHFFFAOYSA-N 0.000 description 1
- HSMVPDGQOIQYSR-KGENOOAVSA-N triflumizole Chemical compound C1=CN=CN1C(/COCCC)=N/C1=CC=C(Cl)C=C1C(F)(F)F HSMVPDGQOIQYSR-KGENOOAVSA-N 0.000 description 1
- XAIPTRIXGHTTNT-UHFFFAOYSA-N triflumuron Chemical compound C1=CC(OC(F)(F)F)=CC=C1NC(=O)NC(=O)C1=CC=CC=C1Cl XAIPTRIXGHTTNT-UHFFFAOYSA-N 0.000 description 1
- RROQIUMZODEXOR-UHFFFAOYSA-N triforine Chemical compound O=CNC(C(Cl)(Cl)Cl)N1CCN(C(NC=O)C(Cl)(Cl)Cl)CC1 RROQIUMZODEXOR-UHFFFAOYSA-N 0.000 description 1
- 239000003744 tubulin modulator Substances 0.000 description 1
- DBHVHTPMRCXCIY-UHFFFAOYSA-N tyclopyrazoflor Chemical compound N1=C(Cl)C(N(C(=O)CCSCCC(F)(F)F)CC)=CN1C1=CC=CN=C1 DBHVHTPMRCXCIY-UHFFFAOYSA-N 0.000 description 1
- JARYYMUOCXVXNK-IMTORBKUSA-N validamycin Chemical compound N([C@H]1C[C@@H]([C@H]([C@H](O)[C@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)CO)[C@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O JARYYMUOCXVXNK-IMTORBKUSA-N 0.000 description 1
- DBXFMOWZRXXBRN-LWKPJOBUSA-N valifenalate Chemical compound CC(C)OC(=O)N[C@@H](C(C)C)C(=O)NC(CC(=O)OC)C1=CC=C(Cl)C=C1 DBXFMOWZRXXBRN-LWKPJOBUSA-N 0.000 description 1
- LESVOLZBIFDZGS-UHFFFAOYSA-N vamidothion Chemical compound CNC(=O)C(C)SCCSP(=O)(OC)OC LESVOLZBIFDZGS-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 241000228158 x Triticosecale Species 0.000 description 1
- WCJYTPVNMWIZCG-UHFFFAOYSA-N xylylcarb Chemical compound CNC(=O)OC1=CC=C(C)C(C)=C1 WCJYTPVNMWIZCG-UHFFFAOYSA-N 0.000 description 1
- 239000005943 zeta-Cypermethrin Substances 0.000 description 1
- 229940048462 zinc phosphide Drugs 0.000 description 1
- DUBNHZYBDBBJHD-UHFFFAOYSA-L ziram Chemical compound [Zn+2].CN(C)C([S-])=S.CN(C)C([S-])=S DUBNHZYBDBBJHD-UHFFFAOYSA-L 0.000 description 1
- FJBGIXKIXPUXBY-UHFFFAOYSA-N {2-[3-(4-chlorophenyl)propyl]-2,4,4-trimethyl-1,3-oxazolidin-3-yl}(imidazol-1-yl)methanone Chemical compound C1=CN=CN1C(=O)N1C(C)(C)COC1(C)CCCC1=CC=C(Cl)C=C1 FJBGIXKIXPUXBY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
Definitions
- the present invention relates to a method for controlling pests on and/or increasing the plant health of a cultivated plant with at least one modification (hereinafter abbreviated as “cultivated plant”) as compared to a respective non-modified control plant.
- the method comprises the application of a pesticidal carboxamide compound (alone or in the form of a mixture comprising such pesticidal carboxamide compound) to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth.
- a pesticidal carboxamide compound (alone or in the form of a mixture comprising such pesticidal carboxamide compound)
- the present invention relates to a method for controlling pests and/or increasing the plant health of a cultivated plant with at least one modification as compared to the respective non-modified control plant, comprising the application of an pesticidal carboxamide compound (again, alone or in the form a mixture comprising such pesticidal carboxamide compound) to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth, wherein said cultivated plant is selected from a group of certain plants with specific modifications as defined further below.
- the methods of the invention relating to cultivated plants are particularly suitable for efficiently controlling arthropodal pests such as arachnids, myriapedes and insects as well as nematodes on cultivated plants.
- pests embrace animal pests (such as insects, acarids or nematodes). Relevant animal pests of different genera and species are provided further below.
- the present invention relates to the use of a pesticidal carboxamide compound alone or in the form of a pesticidal mixture comprising such pesticidal carboxamide compound for protecting a cultivated plant, modified plant propagation material, or its locus of growth, against the attack or infestation by pests.
- the present invention relates to the use of a pesticidal carboxamide compound in pesticidally effective amounts for protecting cultivated plants from row crops such as cotton, corn or soybean plants, the plant propagation material thereof or their locus of growth.
- the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of an pesticidal carboxamide compound to a row crop plant (such as corn, cotton or soybean plant), the plant propagation material thereof or at its locus of growth, also on the pests or their food supply, habitat or breeding grounds.
- a row crop plant such as corn, cotton or soybean plant
- the present invention relates to the method of application or the use of a pesticidal carboxamide compound in pesticidally effective amounts for protecting cultivated plants from row crops such as cotton, corn or soybean plants, the plant propagation material thereof or their locus of growth from the infestions by pests, wherein the pests are selected from the orders of Lepidoptera, Coleoptera or Thysanoptera, and combinations thereof.
- Pests in particular insects from the order of Lepidoptera, destroy growing and harvested crops and attack wooden dwelling and commercial structures, thereby causing large economic loss to the food supply and to property.
- soybean it has e.g. been found that, when the pods begin to form and fill out, any foliage loss greater than 20% will decrease the yield (G. Andrews et al., Insect control guides for cotton, soybeans, corn, grain sorghum, wheat, sweet potatoes and pastures, Mississippi State University Extension Service, Publication 2471, 64 pp. (2009)).
- Anticarsia gemmatalis, Pseudoplusia includens, Spodoptera frugiperda, Spodoptera eridania , and Spodoptera cosmioides for defoliation of soybean genotypes is analyzed by R. C. O. de Freitas Bueno et al. in Pest Manag. Sci. 2011; 67: 170-174.
- Anticarsia gemmatalis was originally the most important defoliator insect occurring on soybean crops, but that nowadays Pseudoplusia includens, Spodoptera frugiperda, Spodoptera eridania , and Spodoptera cosmioides are also considered to be key pests by Brazilian soybean growers.
- cry1F a combination of cry1F and cry1Ac (e.g. DAS 81419) for the reason that cry1F in many species interacts with the known receptor for cry1Ac indicating a similar insecticidal activity, which may contribute to cross-resistance to both toxins (Center for Environmental Risk Assessment, ILSI Research Foundation, Washington D.C., USA, 2013: “A Review of the Environmental Safety of the Cry1F Protein”).
- insect resistance refers to insect resistance against other pesticides and pesticidal mixtures or insect resistance against an insecticidal trait of a plant.
- plants selected from wheat, maize, rice, soybean, and cotton plants may effectively be protected against defoliation by these pests, and a decrease of the yields can thus be prevented.
- the method is also suitable for controlling the above mentioned pests, if they have become resistant against conventional pesticides or pesticidal mixtures, or against the insecticidal trait of a plant.
- the development of a resistance against the insecticidal trait of a plant can be prevented, if the plants are treated with the pesticidal carboxamide compound of the invention.
- the method according to the invention is suitable for controlling pests, against which the insecticidal trait of a plant is not effective, so that a complementary insecticidal activity can advantageously be used.
- cultivated plants with at least one modification are more susceptible to attack or infestation by pests than plants, which have not been modified.
- cultivación of cultivated plants with a modification, which provides insect resistance can be particularly susceptible to certain pests against which the produced toxin is not effective. Moreover, the pests can develop resistance against the toxin, which is produced by the plant.
- plant health comprises various sorts of improvements of plants that are not connected to the control of pests and which do not embrace the reduction of negative consequences of harmful insects.
- plant health is to be understood to denote a condition of the plant and/or its products which is determined by several indicators alone or in combination with each other such as yield (e.g. increased biomass and/or increased content of valuable ingredients), plant vigor (e.g. improved plant growth and/or greener leaves (“greening effect”), quality (e.g. improved content or composition of certain ingredients) and tolerance to abiotic and/or biotic stress.
- yield e.g. increased biomass and/or increased content of valuable ingredients
- plant vigor e.g. improved plant growth and/or greener leaves (“greening effect”)
- quality e.g. improved content or composition of certain ingredients
- tolerance to abiotic and/or biotic stress e.g. improved content or composition of certain ingredients
- Preferred methods and uses according to of this invention comprise compound i) of formula (I) as pesticidal active carboxamide compound I.
- Preferred embodiments of this invention are the methods or the use of the pesticidal active carboxamide compound i) of formula (I) or the tautomers, enantiomers, diastereomers or salts thereof, alone or in mixtures comprising such pesticidal active carboxamide compound.
- inventions of this invention are the methods or the use of the pesticidal active carboxamide compound ii) of formula (Ia) or the tautomers, enantiomers, diastereomers or salts thereof, alone or in mixtures comprising such pesticidal active carboxamide compound.
- Still other embodiments of this invention are the methods or the use of pesticidal active mixtures comprising the carboxamide compounds i) of formula (I) and ii) of formula (Ia) or the tautomers, enantiomers, diastereomers or salts thereof, alone or in mixtures comprising such pesticidal active carboxamide compound mixtures.
- the terms “compound i) of formula (I)”, “compound (ii) of formula (la), or “mixture comprising the carboxamide compounds (i) and (ii)” also include the respective salts, tautomers, stereoisomers, and N-oxides of the carboxamide compounds.
- the above objects may be achieved by the use or application of the pesticidal active carboxamide compound I, preferably compound i) of formula (I) alone.
- the application of the pesticidal active carboxamide compound I, preferably compound i) of formula (I) as only one active agent can be advantageous in terms of practicability and also in connection with insect resistance management.
- the application of a mixture comprising pesticidal active carboxamide compound I, preferably compound i) of formula (I), including the simultaneous, that is joint or separate, application of pesticidal active carboxamide compound I, preferably compound i) of formula (I) and the other pesticidal active ingredient or their successive application on cultivated plants may allow enhanced control of animal pests, compared to the control rates that are possible by application on non-cultivated plants.
- the mixture comprising pesticidal active carboxamide compound I, preferably compound i) of formula (I), and another pesticidal active compound may advantageously be used.
- the pesticidal active carboxamide compound I may be useful in methods of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth, wherein the plant has at least one insecticidal trait, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- Carboxamide derivatives showing generally pesticidal activity have been described previously.
- WO200573165 and WO2010018714 describe carboxamide compounds, their preparation and their use as pest control agents.
- WO2007013150, JP2011-157294, JP2011-157295 and JP2011-157296 describe mixtures of carboxamides with other active ingredients.
- Preparation of the pesticidal active carboxamide compound I can further be accomplished according to standard methods of organic chemistry, e.g. by the methods or working examples described in WO 2010/018857 without being limited to the routes given therein.
- the carboxamide compound I preferably the compound i) of formula (I), includes its tautomers, racemic mixtures, individual pure enantiomers and diasteroemers and the optically active mixtures.
- the carboxamide compound i) of formula (I) is especially suitable for efficiently combating animal pests such as arthropods, gastropods and nematodes including but not limited to: insects from the order of Lepidoptera, for example Achroia grisella, Acleris spp. such as A. fimbriana, A. gloverana, A. variana; Acrolepiopsis assectella, Acronicta major, Adoxophyes spp. such as A. cyrtosema, A. orana; Aedia leucomelas, Agrotis spp. such as A. exclamationis, A. fucosa, A. ipsilon, A. orthogoma, A. segetum, A.
- insects from the order of Lepidoptera for example Achroia grisella, Acleris spp. such as A. fimbriana, A. gloverana, A. variana; Acrolepiopsis assectella, Acronic
- Argyresthia conjugelia, Argyroploce spp., Argyrotaenia spp. such as A. velutinana; Athetis mindara, Austroasca viridigrisea, Autographa gamma, Autographa nigrisigna, Barathra brassicae, Bedellia spp., Bonagota salubricola, Borbo cinnara, Bucculatrix thurberiella, Bupalus piniarius, Busseola spp., Cacoecia spp. such as C. murinana, C.
- Cactoblastis cactorum Cadra cautella, Calingo braziliensis, Calopas theivora, Capua reticulana, Carposina spp. such as C. niponensis, C. sasald; Cephus spp., Chaetocnema aridula, Cheimatobia brumata, Chilo spp. such as C. lndicus, C. suppressalis, C. partellus; Choreutis pariana, Choristoneura spp. such as C. conflictana, C. fumiferana, C. longicellana, C. murinana, C. occidentalis, C.
- kuehniella kuehniella; Epinotia aporema, Epiphyas postvittana, Erannis tiliaria, Erionota thrax, Etiella spp., Eulia spp., Eupoecilia ambiguella, Euproct chrysorrhoea, Euxoa spp., Evetria bouliana, Faronta albilinea, Feltia spp. such as F. subterranean; Galleria mellonella, Gracillaria spp., Grapholita spp. such as G. funebrana, G. moiesta, G.
- H. armigera Heliothis armigera
- H. zea Heliothis zea
- Heliothis spp. such as H. assulta, H. subflexa, H. virescens
- Hellula spp. such as H. undalis, H.
- Mamestra spp. such as M. brassicae, M. configurata; Mamstra brassicae, Manduca spp. such as M. quinquemaculata, M. sexta; Marasmia spp, Marmara spp., Maruca testulalis, Megalopyge Janata, Melanchra picta, Melanitis leda, Mocis spp. such as M. lapites, M.
- operculella Phyllocnistis citrella, Phyllonorycter spp. such as P. blancardella, P. crataegella, P. issikii, P. ringoniella; Pieris spp. such as P. brassicae, P. rapae, P. napi; Pllocrocis tripunctata, Plathypena scabra, Platynota spp. such as P. flavedana, P. idaeusalis, P.
- Tecia solanivora Telehin licus
- Thecla spp. Theresimima ampelophaga, Thyrinteina spp, Tildenia inconspicuella, Tinea spp. such as T. cloacella, T. pellionella; Tineola bisselliella, Tortrix spp. such as T. viridana; Trichophaga tapetzella, Trichoplusia spp. such as T.
- insects from the order of Coleoptera for example Acalymma vittatum, Acanthoscehdes obtectus, Adoretus spp., Agelastica alni, Agrilus spp. such as A. anxius, A. planipennis, A. sinuatus; Agriotes spp. such as A. fuscicollis, A. lineatus, A. obscurus; Alphitobius diaperinus, Amphimallus solstitialis, Anisandrus dispar, AmSoplia austriaca, Anobium punctatum, Anomala diverenta, Anomala rufocuprea, Anoplophora spp. such as A.
- Anthonomus spp. such as A. eugenil, A. grandis, A. pomorum; Anthrenus spp., Aphthona euphoridae, Apion spp., Apogonia spp., Athous haemorrhoidalis, Atomaria spp. such as A. linearis; Attagenus spp., Aulacophora femoralis, Blastophagus piniperda, Blitophaga undata, Bruchidius obtectus, Bruchus spp. such as B. lentis, B. pisorum, B.
- vespertinus Conotrachelus nenuphar, Cosmopolites spp., Costelytra zealandica, Criocenis asparagi, Cryptolestes ferrugineus, Cryptorhynchus lapathl, Ctenicera spp. such as C. destructor; Curculio spp., Cylindrocopturus spp., Cyclocephala spp., Dactylispa balyi, Dectes texanus, Dermestes spp., Diabrotica spp. such as D. undecimpunctata, D. speciosa, D. longicornis, D. semipunctata, D.
- Diaprepes abbreviates, Dichocroais spp., Dicladispa armigera, Diloboderus abderus, Diocalandra frumenfi ( Diocalandra stigmaticollis ), Enaphalodes rufulus, Epilachna spp. such as E. varivestis, E. vigintioctomaculata; Epitrix spp. such as E. hirtipennis, E.
- hypomeces squamosus Hypothenemus spp., lps typographus, Lachnosterna consanguinea, Lasioderma serricome, Latheticus oryzae, Lathridius spp., Lema spp. such as L. bilineata, L. melanopus; Leptinotarsa spp. such as L. decem lineata; Leptispa pygmaea, Limonius californicus, Lissorhoptrus olyzophllus, Lixus spp., Luperodes spp., Lyctus spp. such as L.
- vulneratus Saperda candida, Scolytus schevyrewi, Scyphophorus acupunctatus, Sitona lineatus, Sitophilus spp. such as S. granaria, S. oryzae, S. zeamais; Sphenophorus spp. such as S. Levis; Stegobium paniceum, Sternechus spp. such as S. subsignatus; Strophomorphus ctenotus, Symphyletes spp., Tanymecus spp., Tenebrio molitor, Tenebrioides mauretanicus, Tribolium spp. such as T.
- Trogoderma spp. Tychius spp.
- Xylotrechus spp. such as X. pyrrhoderus
- Zabrus spp. such as Z. tenebrioides
- insects from the order of Diptera for example Aedes spp. such as A. aegypti, A. albopictus, A. vexans; Anastrepha ludens, Anopheles spp. such as A. albimanus, A. crucians, A. freeborni, A. gambiae, A. leucosphyrus, A. maculipennis, A. minimus, A. quadrimaculatus, A. sinensis; Bactrocera invadens, Bibio hortulanus, Calliphora erythrocephala, Calliphora vicina, Ceratitis capitata, Chrysomyia spp. such as C. bezziana, C.
- fuscipes G. morsitans, G. palpalis, G. tachinoides
- Haematobiairritans, Haplodiplosis equestris Hippelates spp., Hylemyia spp. such as H. platura
- Hypoderma spp. such as H. lineata
- Hyppobosca spp. Hydrellia philippina, Leptoconops torrens, Liriomyza spp. such as L. sativae, L. trifolii
- Lucllia spp. such as L. caprin, L. cuprina, L.
- insects from the order of Thysanoptera for example, Basothrips biformis, Dichromothnps corbetti, Dichromothrips ssp., Echinothrips americanus, Enneothrips flavens, Frankliniella spp. such as F. fusca, F. occidentalis, F. tritici; Heliothnps spp., Hercinothrips femoralis, Kakothrips spp., Microcephalothrips abdominalis, Neohydatothnps samayunkur, Pezothrips kellyanus, Rhipiphorothrips cruentatus, Scirtothnps spp. such as S.
- insects from the order of Hemiptera for example, Acizzia jamatonica, Acrosternum spp. such as A. Mare; Acyrthosipon spp. such as A. onoboichis, A. pisum; Adelges laricis, Adelges tsugae, Adelphocoris spp., such as A. rapidus, A.
- Idiocerus spp. Idioscopus spp., Laodelphax striatellus, Lecaniurn spp., Lecanoideus floccissimus, Lepidosaphes spp. such as L. ulmi; Leptocorisa spp., Leptoglossus phyllopus, Lipaphis Lygus spp. such as L. hesperus, L. lineolaris, L.
- Nezara spp. such as N. viridula; Nilaparvata lugens, Nysius huttoni, Oebalus spp. such as O.
- devastatrix Piesma quadrata, Piezodorus spp. such as P. gulldimi; Pinnaspis aspidlistrae, Planococcus spp. such as P. citri, P. ficus; Prosapia bicincta, Protopulvinana pyriformis, Psallus senatus, Pseudacysta persea, Pseudaulacaspis pentagon, Pseudococcus spp. such as P. comstocki; Psylla spp. such as P.
- Pteromalus spp. Pulvinana amygdali, Pyrilla spp., Quadraspidiotus spp., such as Q. perniciosus; Quesada gigas, Rastrococcus spp., Reduvius semils, Rhizoecus americanus, Rhodnius spp., Rhopalomyzus ascalonicus, Rhopalosiphum spp. such as R. pseudobrassicas, R. insertum, R. maidis, R.
- Sagalodes spp., Sahlbergella singularis, Saissetia spp., Sappaphis mala, Sappaphis mall, Scaptocoris spp., Scaphoides titanus, Schizaphis graminum, Schizoneura lanuginosa, Scotinophora spp., Selenaspidus articulatus, Sitobion avenae, Sogata spp., Sogatella furcifera, Solubea insularis, Spissistilus festinus ( Stictocephala festina ), Stephanitis nashi, Stephanitis pyrioides, Stephanitis takeyai, Tenalaphara malayensis, Tetraleurodes perseae, Therioaphis maculate, Thyanta spp.
- T. accerra, T. perditor Tibraca spp., Tomaspis spp., Toxoptera spp. such as T. aurantii; Trialeurodes spp. such as T. abutilonea, T. ricin, T. vaporariorum; Triatoma spp., Trioza spp., Typhlocyba spp., Unaspis spp. such as U. citri, U. yanonensis ; and Viteus vitifolil;
- Paravespula spp. such as P. germanica, P. pennsylvanica, P. vulgaris; Pheidole spp. such as P. megacephala; Pogonomyrmex spp. such as P. barbatus, P. californicus, Pollstes rubiginosa, Prenolepis impairs, Pseudomyrmex gracilis, Schelipron spp., Sirex cyaneus, Solenopsis spp. such as S. geminata, Sinvicta, S.
- Insects from the order Orthoptera for example Acheta domesticus, Calliptamus italicus, Chortoicetes terminifera, Ceuthophilus spp., Diastrammena asynamora, Dociostaurus maroccanus, Gryllotalpa spp. such as G. africana, G. gryllotalpa; Gryllus spp., Hieroglyphus daganensis, Kraussaria angulifera, Locusta spp. such as L. migratoria, L. pardalina; Melanoplus spp. such as M. bivittatus, M. femurrubrum, M. mexicanus, M. sanguinipes, M.
- Pests from the Class Arachnida for example Acari e.g. of the families Argasidae, Ixodidae and Sarcoptidae, such as Amblyomma spp. (e.g. A. americanum, A. variegatum, A. maculatum ), Argas spp. such as A. persicu ), Boophilus spp. such as B. annulatus, B. decoloratus, B. microplus, Dermacentor spp. such as D. silvarum, D. andersom, D. variabilis, Hyalomma spp. such as H. truncatum, Ixodes spp. such as I. ricinus, I.
- Amblyomma spp. e.g. A. americanum, A. variegatum, A. maculatum
- Argas spp. such as A. persicu
- Boophilus spp. such as B.
- rubicundus I. scapularis, I. holocyclus, I. pacificus, Rhipicephalus sanguineus, Ornithodorus spp. such as O. moubata, O. hermsi, O. turicata, Ornithonyssus bacoti, Otobius megnini, Dermanyssus gallinae, Psoroptes spp. such as P. ovis, Rhipicephalus spp. such as R. sanguineus, R. appendiculatus, Rhipicephalus evertsi, Rhizoglyphus spp., Sarcoptes spp. such as S.
- T. cinnabarinus such as Eriophyes sheldoni ; Family Tarsonemidae including Hemitarsonemus spp., Phytonemus pallidus and Polyphagotarsonemus latus, Stenotarsonemus spp. Steneotarsonemus spinki ; Family Tenuipalpidae including Brevipalpus spp. such as B. phoenicis ; Family Tetranychidae including Eotetranychus spp., Eutetranychus spp., Oligonychus spp., Petrobia latens, Tetranychus spp. such as T. cinnabarinus, T. evansi, T. kanzawai, T, pacificus, T.
- Halotydeus destructor Family Demodicidae with species such as Demodex spp.; Family Trombicidea including Trombicula spp.; Family Cellyssidae including Ornothonyssus spp.; Family Pyemotidae including Pyemotes tritici; Tyrophagus putrescentiae ; Family Acaridae including Acarus siro ; Family Araneida including Latrodectus mactans, Tegenaria agrestis, Chiracanthium sp, Lycosa sp Achaearanea tepidariorum and Loxosceles reclusa;
- Pests from the Phylum Nematoda for example, plant parasitic nematodes such as root-knot nematodes, Meloidogyne spp. such as M. hapla, M. incognita, M. Javanica ; cyst-forming nematodes, Globodera spp. such as G. rostochiensis; Heterodera spp. such as H. avenae, H. glycines, H. schachtil, H. trifolii ; Seed gall nematodes, Anguina spp.; Stem and foliar nematodes, Aphelenchoides spp. such as A.
- plant parasitic nematodes such as root-knot nematodes, Meloidogyne spp. such as M. hapla, M. incognita, M. Javanica ; cyst-forming nematodes, Globodera spp. such as G. ros
- Awl nematodes Dolichodorus spp.
- Spiral nematodes Hellocotylenchus multicinctus ; Sheath and sheathoid nematodes, Hemicycliophora spp. and Hemicriconemoides spp.; Hirshmanniella spp.; Lance nematodes, Hoploaimus spp.; False rootknot nematodes, Nacobbus spp.; Needle nematodes, Longidorus spp. such as L. elongatus ; Lesion nematodes, Pratylenchus spp. such as P.
- brachyurus P. neglectus, P. penetrans, P. curvitatus, P. goodeyi ; Burrowing nematodes, Radopholus spp. such as R. similis; Rhadopholus spp.; Rhodopholus spp.; Reniform nematodes, Rotylenchus spp. such as R. robustus, R. reniformis; Scutellonema spp.; Stubby-root nematode, Trichodorus spp. such as T. obtusus, T. primitivus; Paratrichodorus spp. such as P.
- Insects from the order Isoptera for example Calotermes flavicollis, Coptotermes spp. such as C. formosanus, C. gestroi, C. acinaciformis; Cornitermes cumulans, Cryptotermes spp. such as C. brevis, C. cavifrons; Globitermes sulfureus, Heterotermes spp. such as H. aureus, H. longiceps, H. tenuis; Leucotermes flavipes, Odontotermes spp., Incisitermes spp. such as I. minor, I. Snyder, Marginitermes hubbardi, Mastotermes spp. such as M. darwiniensiS Neocapritermes spp. such as N.
- Neotermes spp. Procornitermes spp., ZootermopsiS spp. such as Z. angusticollis, Z. nevadensis, Reticulitermes spp. such as R. hesperus, R. tibialis, R. speratus, R. flavipes, R. grassei, R. lucifugus, R. santonensis, R. virginicus; Termes natalensis,
- Insects from the order Siphonoptera for example Cediopsylla simples, Ceratophyllus spp., Ctenocephalides spp. such as C. fells, C. canis, Xenopsylla cheopis, Pulex irritans, Trichodectes canis, Tunga penetrans , and Nosopsyllus fasciatus,
- Thysanura for example Lepisma saccharin, Ctenolepisma urban , and Thermobia domestica
- Pests from the class Chilopoda for example Geophilus spp., Scutigera spp. such as Scutigera coleoptrata;
- Pests from the class Diplopoda for example Blaniulus guttulatus, Julus spp., Narceus spp.,
- Pests from the class Symphyla for example Scutigerella immaculata
- Onychiurus spp. such as Onychiurus armatus
- Pests from the order Isopoda for example, Armadillidium vulgare, Oniscus asellus, Porcellio scaber,
- Insects from the order Phthiraptera for example Damalinia spp., Pediculus spp. such as Pediculus humanus capitis, Pediculus humanus corporis, Pediculus humanus humanus; Pthirus pubis, Haematopinus spp. such as Haematopinus eurysternus, Haematopinus suis; Linognathus spp. such as Linognathus vituli; Bovicola bovis, Menopon gallinae, Menacanthus stramineus and Solenopotes capillatus, Trichodectes spp.,
- Examples of further pest species which may be controlled by the compound I, preferably compound i) of formula (I) include: from the Phylum Mollusca, class Bivalvia, for example, Dreissena spp.; class Gastropoda, for example, Arion spp., Biomphalaria spp., Bulinus spp., Deroceras spp., Galba spp., Lymnaea spp., Oncomelania spp., Pomacea canaliclata, Succinea spp.; from the class of the helminths, for example, Ancylostoma duodenale, Ancylostoma ceylanicum, Acylostoma braziliensis, Ancylostoma spp., Ascaris lumbricoides, Ascaris spp., Brugia malap, Brugia timon, Bunostomum spp., Chabertia spp., Cion
- carboxamide compound ii) of formula (Ia) and mixtures comprising compound i) of formula (I) and compound ii) of formula (Ia) are suitable for efficiently combating animal pests such as arthropods, gastropods and nematodes as set out above.
- Mixtures comprising the carboxamide compounds i) and ii) are mixtures comprising both compound i) of formula (I) and compound ii) of formula (Ia).
- the compounds I are suitable for use in protecting crops, plants, plant propagation materials, such as seeds, or its locus of growth, from attack or infestation by animal pests. Therefore, the present invention also relates to a plant protection method, which comprises contacting crops, plants, plant propagation materials, such as seeds, or its locus of growth, to be protected from attack or infestation by animal pests, with a pesticidally effective amount of the compound I, preferably compound i) of formula (I).
- the compound I preferably compound i) of formula (I), are also suitable for use in combating or controlling animal pests.
- the present invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, such as seeds, or soil, or the area, material or environment in which the animal pests are growing or may grow, with a pesticidally effective amount of the compound i) of formula (I).
- the present invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, such as seeds, or soil, or the area, material or environment in which the animal pests are growing or may grow, with a pesticidally effective amount of compound ii) of formula (Ia).
- the present invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, such as seeds, or soil, or the area, material or environment in which the animal pests are growing or may grow, with a pesticidally effective amount of mixtures comprising the carboxamide compounds i) and ii).
- the compounds I, preferably compound i) of formula (I), are effective through both contact and ingestion. Furthermore, the compounds I, preferably compound i) of formula (I), can be applied to any and all developmental stages, such as egg, larva, pupa, and adult.
- the compound I, preferably compound i) of formula (I), can be applied as such or in form of compositions comprising them as defined above. Furthermore, the compound I, preferably compound i) of formula (I), can be applied together with a mixing partner as defined above or in form of compositions comprising said mixtures as defined above.
- the components of said mixture can be applied simultaneously, jointly or separately, or in succession, that is immediately one after another and thereby creating the mixture “in situ” on the desired location, e.g. the plant, the sequence, in the case of separate application, generally not having any effect on the result of the control measures.
- the application can be carried out both before and after the infestation of the crops, plants, plant propagation materials, such as seeds, soil, or the area, material or environment by the pests.
- Suitable application methods include inter alia soil treatment, seed treatment, in furrow application, and foliar application.
- Soil treatment methods include drenching the soil, drip irrigation (drip application onto the soil), dipping roots, tubers or bulbs, or soil injection.
- Seed treatment techniques include seed dressing, seed coating, seed dusting, seed soaking, and seed pelleting.
- furrow applications typically include the steps of making a furrow in cultivated land, seeding the furrow with seeds, applying the pesticidally active compound I, preferably compound i) of formula (I), to the furrow, and closing the furrow.
- Foliar application refers to the application of the pesticidally active compound I, preferably compound i) of formula (I), to plant foliage, e.g. through spray equipment.
- pheromones for specific crops and pests are known to a skilled person and publicly available from databases of pheromones and semiochemicals, such as http://www.pherobase.com.
- the term “contacting” includes both direct contact (applying the compounds/mixtures/compositions directly on the animal pest or plant—typically to the foliage, stem or roots of the plant) and indirect contact (applying the compounds/mixtures/compositions to the locus, i.e. habitat, breeding ground, plant, seed, soil, area, material or environment in which a pest is growing or may grow, of the animal pest or plant).
- animal pest includes arthropods, gastropods, and nematodes.
- Preferred animal pests according to the invention are arthropods, preferably insects and arachnids, in particular insects.
- Insects, which are of particular relevance for crops, are typically referred to as crop insect pests.
- crop refers to both, growing and harvested crops.
- plant includes cereals, e.g. durum and other wheat, rye, barley, triticale, oats, rice, or maize (fodder maize and sugar maize/sweet and field corn); beet, e.g. sugar beet or fodder beet; fruits, such as pomes, stone fruits or soft fruits, e.g.
- iceberg lettuce chicory, cabbage, asparagus, cabbages, carrots, onions, garlic, leeks, tomatoes, potatoes, cucurbits or sweet peppers; lauraceous plants, such as avocados, cinnamon or camphor; energy and raw material plants, such as corn, soybean, rapeseed, sugar cane or oil palm; tobacco; nuts, e.g. walnuts; pistachios; coffee; tea; bananas; vines (table grapes and grape juice grape vines); hop; sweet leaf (also called Stevia ); natural rubber plants or ornamental and forestry plants, such as flowers (e.g.
- Preferred plants include potatoes sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rapeseed, legumes, sunflowers, coffee or sugar cane; fruits; vines; ornamentals; or vegetables, such as cucumbers, tomatoes, beans or squashes.
- plant is to be understood as including wild type plants and plants, which have been modified by either conventional breeding, or mutagenesis or genetic engineering, or by a combination thereof.
- Plants which have been modified by mutagenesis or genetic engineering, and are of particular commercial importance, include alfalfa, rapeseed (e.g. oilseed rape), bean, carnation, chicory, cotton, eggplant, eucalyptus, flax, lentil, maize, melon, papaya, petunia, plum, poplar, potato, rice, soybean, squash, sugar beet, sugarcane, sunflower, sweet pepper, tobacco, tomato, and cereals (e.g. wheat), in particular maize, soybean, cotton, wheat, and rice.
- rapeseed e.g. oilseed rape
- the one or more mutagenized or integrated genes are preferably selected from pat, epsps, cry1Ab, bar, cry1Fa2, cry1Ac, cry34Ab1, cry35AB1, cry3A, cryF, cry1F, mcry3a, cry2Ab2, cry3Bb1, cry1A.105, dfr, barnase, vip3Aa20, barstar, als, bxn, bp40, asn1, and ppo5.
- the mutagenesis or integration of the one or more genes is performed in order to improve certain properties of the plant. Such properties, also known as traits, include abiotic stress tolerance, altered growth/yield, disease resistance, herbicide tolerance, insect resistance, modified product quality, and pollination control.
- herbicide tolerance e.g. imidazolinone tolerance, glyphosate tolerance, or glufosinate tolerance
- Several plants have been rendered tolerant to herbicides by mutagenesis, for example Clearfield® oilseed rape being tolerant to imidazolinones, e.g. imazamox.
- genetic engineering methods have been used to render plants, such as soybean, cotton, corn, beets and oil seed rape, tolerant to herbicides, such as glyphosate and glufosinate, some of which are commercially available under the trade names RoundupReady® (glyphosate) and LibertyLink® (glufosinate).
- insect resistance is of importance, in particular lepidopteran insect resistance and coleopteran insect resistance.
- Insect resistance is typically achieved by modifying plants by integrating cry and/or vip genes, which were isolated from Bacillus thuringiensis (Bt), and code for the respective Bt toxins. Genetically modified plants with insect resistance are commercially available under trade names including WideStrike®, Bollgard®, Agrisure®, Herculex®, YieldGard®, Genuity®, and Intacta®. Plants may be modified by mutagenesis or genetic engineering either in terms of one property (singular traits) or in terms of a combination of properties (stacked traits). Stacked traits, e.g. the combination of herbicide tolerance and insect resistance, are of increasing importance.
- plant propagation material refers to all the generative parts of the plant such as seeds and vegetative plant material such as cuttings and tubers (e.g. potatoes), which can be used for the multiplication of the plant. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants. Seedlings and young plants, which are to be transplanted after germination or after emergence from soil, may also be included. These plant propagation materials may be treated prophylactically with a plant protection mixture either at or before planting or transplanting.
- seed embraces seeds and plant propagules of all kinds including but not limited to true seeds, seed pieces, suckers, corms, bulbs, fruit, tubers, grains, cuttings, cut shoots and the like, and means in a preferred embodiment true seeds.
- pesticidally effective amount means the amount of active ingredient needed to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target organism.
- the pesticidally effective amount can vary for the various compounds/mixtures/compositions used in the invention.
- a pesticidally effective amount of the compositions will also vary according to the prevailing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, and the like.
- the quantity of active ingredient ranges from 0.0001 to 500 g per 100 m 2 , preferably from 0.001 to 20 g per 100 m 2 .
- the rate of application of the active ingredients of this invention may be in the range of 0.0001 g to 4000 g per hectare, e.g. from 1 g to 2 kg per hectare or from 1 g to 750 g per hectare, desirably from 1 g to 100 g per hectare, more desirably from 10 g to 50 g per hectare, e.g., 10 to 20 g per hectare, 20 to 30 g per hectare, 30 to 40 g per hectare, or 40 to 50 g per hectare.
- the compounds I, preferably compound i) of formula (I), are particularly suitable for use in the treatment of seeds in order to protect the seeds from insect pests, in particular from soil-living insect pests, and the resulting seedling's roots and shoots against soil pests and foliar insects.
- the present invention therefore also relates to a method for the protection of seeds from insects, in particular from soil insects, and of the seedling's roots and shoots from insects, in particular from soil and foliar insects, said method comprising treating the seeds before sowing and/or after pregermination with the compound I, preferably compound i) of formula (I).
- the protection of the seedling's roots and shoots is preferred. More preferred is the protection of seedling's shoots from piercing and sucking insects, chewing insects and nematodes.
- seed treatment comprises all suitable seed treatment techniques known in the art, such as seed dressing, seed coating, seed dusting, seed soaking, seed pelleting, and in-furrow application methods.
- seed treatment application of the compound I, preferably compound i) of formula (I) is carried out by spraying or by dusting the seeds before sowing of the plants and before emergence of the plants.
- the present invention also comprises seeds coated with or containing the active compound I, preferably compound i) of formula (I).
- the term “coated with and/or containing” generally signifies that the active ingredient is for the most part on the surface of the propagation product at the time of application, although a greater or lesser part of the ingredient may penetrate into the propagation product, depending on the method of application. When the said propagation product is (re)planted, it may absorb the active ingredient.
- Suitable seed is for example seed of cereals, root crops, oil crops, vegetables, spices, ornamentals, for example seed of durum and other wheat, barley, oats, rye, maize (fodder maize and sugar maize/sweet and field corn), soybeans, oil crops, crucifers, cotton, sunflowers, bananas, rice, oilseed rape, turnip rape, sugarbeet, fodder beet, eggplants, potatoes, grass, lawn, turf, fodder grass, tomatoes, leeks, pumpkin/squash, cabbage, iceberg lettuce, pepper, cucumbers, melons, Brassica species, melons, beans, peas, garlic, onions, carrots, tuberous plants such as potatoes, sugar cane, tobacco, grapes, petunias, geranium/pelargoniums, pansies and impatiens.
- the active compound I preferably compound i) of formula (I)
- the present invention relates to the use of the carboxamide compound i) of formula (I) for protecting a cultivated plant, cultivated plant propagation material, or its locus of growth, against the attack or infestation by pests.
- the present invention relates to the use of the carboxamide compound ii) of formula (Ia) for protecting a cultivated plant, cultivated plant propagation material, or its locus of growth, against the attack or infestation by pests.
- the present invention relates to the use of mixtures comprising the carboxamide compounds i) and ii) for protecting a cultivated plant, cultivated plant propagation material, or its locus of growth, against the attack or infestation by pests.
- the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of the carboxamide compound compound i) of formula (I) to a cultivated plant, cultivated plant propagation material, or its locus of growth; the pests or their food supply, habitat or breeding grounds.
- the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of the carboxamide compound ii) of formula (Ia) to a cultivated plant, cultivated plant propagation material, or its locus of growth; the pests or their food supply, habitat or breeding grounds.
- the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of a mixture comprising the carboxamide compounds i) and ii) to a cultivated plant, cultivated plant propagation material, or its locus of growth; the pests or their food supply, habitat or breeding grounds.
- the application of the carboxamide compound I, preferably compound i) of formula (I) in connection with the above use or method includes both contact with the cultivated plant or cultivated plant propagation material and contact with its locus of growth.
- locus of growth is to be understood as the locus, where the plant is growing, in particular the soil or water, in which the plant is growing.
- the methods of the present invention relates in one embodiment to the application to the pests or their food supply, habitat or breeding grounds.
- the carboxamide compound i) of formula (I) is applied to the foliage of the plants, preferably in an amount of from 1 g to 100 g per hectare, more preferably in an amount of from 10 g to 50 g per hectare.
- the carboxamide compound ii) of formula (Ia) is applied to the foliage of the plants, preferably in an amount of from 1 g to 100 g per hectare, more preferably in an amount of from 10 g to 50 g per hectare.
- the mixture comprising the carboxamide compounds i) and ii) is applied to the foliage of the plants, preferably in an amount of from 1 g to 100 g per hectare, more preferably in an amount of from 10 g to 50 g per hectare.
- the carboxamide compound i) of formula (I) is applied to the plant propagation material, preferably the seeds of a plant.
- the carboxamide compound ii) of formula (Ia) is applied to the plant propagation material, preferably the seeds of a plant.
- the mixture comprising the carboxamide compounds i) and ii) is applied to the plant propagation material, preferably the seeds of a plant.
- the carboxamide compound i) of formula (I) is applied to the seeds of the plants, preferably in an amount of from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed.
- the carboxamide compound ii) of formula (Ia) is applied to the seeds of the plants, preferably in an amount of from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed.
- the mixture comprising the carboxamide compounds i) and ii) is applied to the seeds of the plants, preferably in an amount of from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed.
- the components of the mixture can be as mentioned above—applied simultaneously, jointly or separately, or in succession, that is immediately one after another and thereby creating the mixture “in situ” on the desired location, e.g. the plant, the sequence, in the case of separate application, generally not having any effect on the result of the control measures.
- the application methods, uses and mixtures of the present invention are particularly useful for controlling insects of the orders Lepidoptera, Coleoptera and Thysanoptera.
- the application methods, uses and mixtures of the present invention are especially suitable for efficiently combating pests like insects from the order of the lepidopterans (Lepidoptera), beetles (Coleoptera) and thrips (Thysanoptera).
- the pests are Anticarsia gemmatalis.
- the pests are Spodoptera frugiperda.
- the pests are Spodoptera eridania.
- the pests are Spodoptera cosmioides.
- the plant is a plant, which has been modified by conventional breeding, i.e. a plant, which has not been modified by mutagenesis or genetic engineering.
- the plant is a plant, which has been modified by conventional breeding, i.e. a plant, which has not been modified by mutagenesis or genetic engineering.
- the plant is a plant, which has been modified by conventional breeding, i.e. a plant, which has not been modified by mutagenesis or genetic engineering.
- the plant which has not been modified by mutagenesis or genetic engineering, is selected from the group consisting of wheat, maize, rice, soybean, and cotton, and is more preferably a soybean plant.
- the plant is a plant, which has been modified by mutagenesis or genetic engineering, preferably by genetic engineering.
- one or more genes have been mutagenized or integrated into the genetic material of the plant, which are selected from pat, epsps, cry1 Ab, bar, cry1 Fa2, cry1 Ac, cry34Ab1, cry35AB1, cry3A, cryF, cry1F, mcry3a, cry2Ab2, cry3Bb1, cry1A.105, dfr, barnase, vip3Aa20, barstar, als, bxn, bp40, asn1, and ppo5.
- the plant which has been modified by mutagenesis or genetic engineering, exhibits one or more traits selected from the group consisting of abiotic stress tolerance, altered growth/yield, disease resistance, herbicide tolerance, insect resistance, modified product quality, and pollination control.
- the plant exhibits herbicide tolerance, insect resistance or a combination thereof.
- the plant is a plant, which has been modified by mutagenesis or genetic engineering, and which corresponds to any one of rows A1 to A385 of table A.
- Dianthus caryophyllus ST (Color)/bp40 (f3′5′h) ST (Color)/sfl (f3′5′h) HT (SU)/surB A53 Carnation 25947 IFD-25947-1 Moonpearl TM ST (Color)/bp40 Suntory Ltd.
- Dianthus caryophyllus (f3′5′h) ST (Color)/dfr ST (Color)/dfr-diaca HT (SU)/surB A54 Carnation 25958 IFD-25958-3 Moonberry TM ST (Color)/bp40 Suntory Ltd.
- Dianthus caryophyllus (f3′5′h) ST (Color)/dfr ST (Color)/dfr-diaca HT (SU)/surB A55 Carnation 264 ⁇ 7 IFD-264 ⁇ 7-2 Moonvelvet TM ST (Color)/hfl Suntory Ltd.
- Dianthus caryophyllus (f3′5′h) ST (Color)/cytb5 HT (SU)/surB A56 Carnation 4 FLO- ⁇ 4-9 Moondust TM ST (Color)/dfr Florigene Dianthus caryophyllus ST (Color)/hfl Pty. Ltd.
- Perkebunan Nusantara XI (Persero) A362 Sugarcane NXI-4T NXI-4T not available Y&S (DT)/RmBetA PT Saccharum sp.
- Perkebunan Nusantara XI (Persero) A363 Sugarcane NXI-6T NXI-6T not available Y&S (DT)/RmBetA PT Saccharum sp.
- Herbicide Tolerance HT Gly) glyphosate tolerance HT (Glu) glufosinate tolerance HT (SU) sulfonylurea tolerance HT (Imi) imidazolinone tolerance HT (2,4-D) resistance against 2,4-D Choline HT (Dic) dicamba tolerance HT (Gly + Dicamba) glyphosate & dicamba tolerance HT (HPPD) HPPD inhibitor resistance HT (Ox) oxynil herbicide tolerance (e.g. bronnoxynil) HT (Cyc) cyclohexanone herbicide tolerance (e.g.
- IR Insect resistance including IR (BL) broad spectrum resistance against lepidopterans (above ground Nematodes) worms)
- SCN soybean Cyst Nematode resistance
- CB corn borer resistance
- IR (BRun) broad range resistance not further specified
- the plant which has been modified by mutagenesis or genetic engineering, is selected from the group consisting of wheat, maize, rice, soybean, and cotton, and is more preferably a soybean plant, particularly any one of the soybean plants according to rows A-325 to A355 of table A.
- the plant which has been modified by mutagenesis or genetic engineering, is a soybean plant exhibiting insect resistence, in particular Lepidopteran resistance, and optionally at least one further trait, preferably herbicide tolerance, e.g. glyphosate tolerance or glufosinate tolerance.
- herbicide tolerance e.g. glyphosate tolerance or glufosinate tolerance.
- Preferred soybean plants include the soybean plants according to one row of table B.
- the plant, which has been modified by mutagenesis or genetic engineering is a soybean plant, which has been modified by genetic engineering by integrating one or more genes into the genetic material of the soybean, wherein insect resistance is provided by one or more genes selected from the group consisting of cry1Ac, cry1F, cry1A.105, cry2Ab2, and combinations thereof, preferably by cry1Ac, cry1F, or a combination thereof, and more preferably by cry1Ac.
- herbicide tolerance is additionally provided by one or more genes selected from the group consisting of pat, bar, 2mepsps, cp4 epsps, and mepsps.
- Preferred soybean plants include soybean plants, which have been modified by integrating at least one gene or gene combination according to one row of Table C.
- the pests are Anticarsia gemmatalis and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- the pests are Spodoptera frugiperda and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- the pests are Spodoptera eridania and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- the pests are Spodoptera cosmioides and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- the present invention also relates to certain uses and methods comprising the application of the carboxamide compound I selected from compound i) of formula (I), compound ii) of formula (Ia) and mixtures comprising the carboxamide compounds i) and ii).
- the pests are Anticarsia gemmatalis.
- the pests are Spodoptera frugiperda.
- the pests are Spodoptera eridania.
- the pests are Spodoptera cosmioides.
- the soybean plant is a soybean plant, which has been modified by conventional breeding, i.e. a soybean plant, which has not been modified by mutagenesis or genetic engineering.
- the soybean plant is a soybean plant, which has been modified by conventional breeding, i.e. a soybean plant, which has not been modified by mutagenesis or genetic engineering.
- the soybean plant is a soybean plant, which has been modified by mutagenesis or genetic engineering.
- the soybean plant is a soybean plant, which has been modified by mutagenesis or genetic engineering.
- soybean plants which have been modified by mutagenesis or genetic engineering, have been defined above.
- the soybean plant has been modified by genetic engineering and exhibits insect resistance, in particular lepidopteran resistance, wherein insect resistance is provided by one or more genes selected from the group consisting of cry1Ac, cry1F, cry1A.105, cry2Ab2, and combinations thereof, preferably by cry1Ac, cry1F, or a combination thereof, and more preferably by cry1Ac.
- the soybean plant exhibits at least one further trait, preferably herbicide tolerance, e.g. glyphosate tolerance or glufosinate tolerance, wherein herbicide tolerance is preferably provided by one or more genes selected from the group consisting of pat, bar, 2mepsps, cp4 epsps, and mepsps.
- Particularly preferred soybean plants include soybean plants, which are selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84 as defined above.
- the plant is a soybean plant, which has been modified by mutagenesis or genetic
- the pests are Anticarsia gemmatalis and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- the pests are Spodoptera frugiperda and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- the pests are Spodoptera eridania and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- the pests are Spodoptera cosmioides and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- the mixture of the invention is a binary mixture, i.e. a mixture, which does not comprise any further pesticidal compounds apart from the carboxamide compound i) of formula (I) and one other pesticidal active ingredient.
- the mixture of the invention is a binary mixture, i.e. a mixture, which does not comprise any further pesticidal compounds apart from the carboxamide compound ii) of formula (Ia) and one other pesticidal active ingredient.
- the mixture of the invention is a mixture, which does not comprise any further pesticidal compounds apart from the mixture comprising the carboxamide compounds i) and ii) and one other pesticidal active ingredient.
- the mixture of the present invention comprises a ternary mixture comprising the carboxamide compound i) of formula (I), a second pesticidal compound as component II and a third pesticidal compound as component III, wherein the pesticidal compounds II and III are both an insecticide or both a fungicide or one an insecticide and the other a fungicide.
- the mixture of the present invention comprises a ternary mixture comprising the carboxamide compound ii) of formula (Ia), a second pesticidal compound as component II and a third pesticidal compound as component III, wherein the pesticidal compounds II and III are both an insecticide or both a fungicide or one an insecticide and the other a fungicide.
- the mixture of the present invention comprises a mixture comprising the carboxamides compounds i) and ii), another pesticidal compound as component II and still another pesticidal compound as component III, wherein the pesticidal compounds II and III are both an insecticide or both a fungicide or one an insecticide and the other a fungicide.
- the mixture of the present invention comprises a multinary mixture of the carboxamide compound i) of formula (I) and three or four or more other pesticidal compounds as components II, III, IV or V etc., wherein these further pesticidal compounds are insecticides and/or fungicides.
- the mixture of the present invention comprises a multinary mixture of the carboxamide compound ii) of formula (Ia) and three or four or more other pesticidal compounds as components II, III, IV or V etc., wherein these further pesticidal compounds are insecticides and/or fungicides.
- the mixture of the present invention comprises a multinary mixture of the carboxamide compounds i), ii) and three or four or more other pesticidal compounds as components II, III, IV or V etc., wherein these further pesticidal compounds are insecticides and/or fungicides.
- the present invention also relates to an agrochemical composition, which comprises a mixture according to the present invention and an auxiliary.
- Mixing partners can be selected from pesticides, in particular insecticides, nematicides, and acaricides, fungicides, herbicides, plant growth regulators, fertilizers, and the like.
- Preferred mixing partners are insecticides, nematicides and fungicides.
- M.1 Acetylcholine esterase (AChE) inhibitors from the class of: M.1A carbamates, for example aldicarb, alanycarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, trimethacarb, XMC, xylylcarb and triazamate; or from the class of M.1B organophosphates, for example acephate, azamethiphos, azinphos-ethyl, azinphosmethyl, cadusafos, chlorethoxyfos, chlorfenvin
- GABA-gated chloride channel antagonists such as: M.2A cyclodiene organochlorine compounds, as for example endosulfan or chlordane; or M.2B fiproles (phenylpyrazoles), as for example ethiprole, fipronil, flufiprole, pyrafluprole and pyriprole;
- M.3 Sodium channel modulators from the class of M.3A pyrethroids for example acrinathrin, allethrin, d-cis-trans allethrin, d-trans allethrin, bifenthrin, bioallethrin, bioallethrin S-cylclopentenyl, bioresmethrin, cycloprothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, empenthrin, esfenvalerate, etofenprox, fenpropathr
- M.4 Nicotinic acetylcholine receptor agonists from the class of M.4A neonicotinoids, for example acetamiprid, clothianidin, cycloxaprid, dinotefuran, imidacloprid, nitenpyram, thiacloprid and thiamethoxam; or the compounds M.4A.2: (2E+1-[(6-Chloropyridin-3-yl)methyl]-N′-nitro-2-pentylidenehydrazinecarboxinnidamide; or M4.A.3: 1-[(6-Chloropyridin-3-yl)methyl]-7-methyl-8-nitro-5-propoxy-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridine; or from the class M.4B nicotine;
- M.6 Chloride channel activators from the class of avermectins and milbemycins, for example abamectin, emamectin benzoate, ivermectin, lepimectin or milbemectin;
- M.7 Juvenile hormone mimics such as M.7A juvenile hormone analogues as hydroprene, kinoprene and methoprene; or others as M.7B fenoxycarb or M.7C pyriproxyfen;
- M.8 miscellaneous non-specific (multi-site) inhibitors for example M.8A alkyl halides as methyl bromide and other alkyl halides, or M.8B chloropicrin, or M.8C sulfuryl fluoride, or M.8D borax, or M.8E tartar emetic;
- M.9 Selective homopteran feeding blockers for example M.9B pymetrozine, or M.9C flonicamid;
- M.10 Mite growth inhibitors for example M.10A clofentezine, hexythiazox and diflovidazin, or M.10 B etoxazole;
- M.11 Microbial disruptors of insect midgut membranes for example bacillus thuringiensis or bacillus sphaericus and the insecticdal proteins they produce such as bacillus thuringiensis subsp. israelensis, bacillus sphaericus, bacillus thuringiensis subsp. aizawai, bacillus thuringiensis subsp. kurstaki and bacillus thuringiensis subsp. tenebrionis , or the Bt crop proteins: Cry1Ab, Cry1Ac, Cry1Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb and Cry34/35Ab1;
- M.12 Inhibitors of mitochondrial ATP synthase for example M.12A diafenthiuron, or M.12B organotin miticides such as azocyclotin, cyhexatin or fenbutatin oxide, or M.12C propargite, or M.12D tetradifon;
- Nicotinic acetylcholine receptor (nAChR) channel blockers for example nereistoxin analogues as bensultap, cartap hydrochloride, thiocyclam or thiosultap sodium;
- benzoylureas as for example bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, or triflumuron;
- Ecdyson receptor agonists such as diacylhydrazines, for example methoxyfenozide, tebufenozide, halofenozide, fufenozide or chromafenozide;
- Octopamin receptor agonists as for example amitraz
- M.20 Mitochondrial complex III electron transport inhibitors for example M.20A hydramethylnon, or M.206 acequinocyl, or M.20C fluacrypyrim;
- M.21 Mitochondrial complex I electron transport inhibitors for example M.21A METI acaricides and insecticides such as fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad or tolfenpyrad, or M.216 rotenone;
- M.22 Voltage-dependent sodium channel blockers for example M.22A indoxacarb, or M.22B metaflumizone, or M.22B.1: 2-[2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl] ⁇ ethylidene]-N-[4-(difluoromethoxy)phenyl]-hydrazinecarboxamide or M.22B.2: N-(3-Chloro-2-methylphenyl)-2-[(4-chlorophenyl)[4-[methyl(methylsulfonyl)amino]phenyl] ⁇ methylene]-hydrazinecarboxamide;
- M.23 Inhibitors of the of acetyl CoA carboxylase such as Tetronic and Tetramic acid derivatives, for example spirodiclofen, spiromesifen or spirotetramat;
- M.24 Mitochondrial complex IV electron transport inhibitors for example M.24A phosphine such as aluminium phosphide, calcium phosphide, phosphine or zinc phosphide, or M.246 cyanide;
- Mitochondrial complex II electron transport inhibitors such as beta-ketonitrile derivatives, for example cyenopyrafen or cyflumetofen;
- M.28 Ryanodine receptor-modulators from the class of diamides, as for example flubendiamide, chlorantraniliprole (Rynaxypyr®), cyantraniliprole (Cyazypyr®), tetraniliprole, or the phthalamide compounds M.28.1: (R)-3-Chlor-N1- ⁇ 2-methyl-4-[1,2,2,2 tetrafluor-1-(trifluormethyl)ethyl]phenyl ⁇ -N2-(1-methyl-2-methylsulfonylethyl)phthalannid and M.28.2: (S)-3-Chlor-N1- ⁇ 2-methyl-4-[1,2,2,2 tetrafluor-1-(trifluormethyl)ethyl]phenyl ⁇ -N2-(1-methyl-2-methylsulfonylethyl)phthalamid, or the compound M.28.3: 3-bromo-N- ⁇ 2-bromo-4-chloro-6-[(1-
- M.29 insecticidal active compounds of unknown or uncertain mode of action, as for example afidopyropen, afoxolaner, azadirachtin, amidoflumet, benzoximate, bifenazate, bromopropylate, chinomethionat, cryolite, dicloromezotiaz, dicofol, flufenerim, flometoquin, fluensulfone, fluhexafon, fluopyram, flupyradifurone, fluralaner, metoxadiazone, piperonyl butoxide, pyflubumide, pyridalyl, pyrifluquinazon, sulfoxaflor, tioxazafen, triflunnezopyrinn, or the compounds
- M.29.6a (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide
- M.29.6b (E/Z)—N-[1-[(6-chloro-5-fluoro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide
- M.29.6c (E/Z)-2,2,2-trifluoro-N-[1-[(6-fluoro-3-pyridyl)methyl]-2-pyridylidene]acetamide
- M.29.6d (E/Z)—N-[1-[(6-bromo-3-pyridyl)methyl]-2-pyridy
- M.29.9.a 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]-2-methyl-N-(1-oxothietan-3-yl)benzamide; or M.29.9.b): fluxametamide; or
- M.29.11 a compound selected from the group of M.29.11, wherein the compound is selected from M.29.11b) to M.29.11p): M.29.11.b) 3-(benzoylmethylamino)-N-[2-bromo-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]-6-(trifluoromethyl)phenyl]-2-fluoro-benzamide; M.29.11.c) 3-(benzoylmethylamino)-2-fluoro-N-[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]-benzamide; M.29.11.d) N-[3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl
- M.29.14a 1-[(6-Chloro-3-pyridinyl)methyl]-1,2,3,5,6,7-hexahydro-5-methoxy-7-methyl-8-nitro-imidazo[1,2-a]pyridine; or M.29.14b) 1-[(6-Chloropyridin-3-yl)methyl]-7-methyl-8-nitro-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridin-5-ol; or the compounds
- M.29.16a 1-isopropyl-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; or M.29.16b) 1-(1,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16c) N,5-dimethyl-N-pyridazin-4-yl-1-(2,2,2-trifluoro-1-methyl-ethyl)pyrazole-4-carboxamide; M.29.16d) 1-[1-(1-cyanocyclopropyl)ethyl]-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16e) N-ethyl-1-(2-fluoro-1-methyl-propyl)-5-methyl-N-pyridazin-4-yl-pyrazole-4
- M.29.17 a compound selected from the compounds M.29.17a) to M.29.17j): M.29.17a) N-(1-methylethyl)-2-(3-pyridinyl)-2H-indazole-4-carboxamide; M.29.17b) N-cyclopropyl-2-(3-pyridinyl)-2H-indazole-4-carboxamide; M.29.17c) N-cyclohexyl-2-(3-pyridinyl)-2H-indazole-4-carboxamide; M.29.17d) 2-(3-pyridinyl)-N-(2,2,2-trifluoroethyl)-2H-indazole-4-carboxamide; M.29.17e) 2-(3-pyridinyl)-N-[(tetrahydro-2-furanyl)methyl]-2H-indazole-5-carboxamide; M.29.17f) methyl 2-[[2-
- M.29.18 a compound selected from the compounds M.29.18a) to M.29.18d): M.29.18a) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropylsulfanyl)propanamide; M.29.18b) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropylsulfinyl)propanamide; M.29.18c) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-3-[(2,2-difluorocyclopropyl)methylsulfanyl]-N-ethyl-propanamide; M.29.18d) N-[3-chloro-1-(3-pyridyl
- the M.4 neonicotinoid cycloxaprid is known from WO2010/069266 and WO2011/069456
- the neonicotinoid M.4A.2 is known from WO2013/003977
- the neonicotinoid M.4A.3 (approved as paichongding in China) is known from WO2007/101369.
- the metaflumizone analogue M.22B.1 is described in CN10171577 and the analogue M.22B.2 in CN102126994.
- the phthalamides M.28.1 and M.28.2 are both known from WO2007/101540.
- the anthranilamide M.28.3 is described in WO2005/077934.
- the hydrazide compound M.28.4 is described in WO2007/043677.
- the anthranilamides M.28.5a) to M.28.5d) and M.28.5h) are described in WO 2007/006670, WO2013/024009 and WO2013/024010, the anthranilamide M.28.5i) is described in WO2011/085575, M.28.5j) in WO2008/134969, M.28.5k) in US2011/046186 and M.28.5l) in WO2012/034403.
- the diamide compound M.28.6 can be found in WO2012/034472.
- the spiroketal-substituted cyclic ketoenol derivative M.29.3 is known from WO2006/089633 and the biphenyl-substituted spirocyclic ketoenol derivative M.29.4 from WO2008/067911.
- the triazoylphenylsulfide M.29.5 is described in WO2006/043635, and biological control agents on the basis of bacillus firmus are described in WO2009/124707.
- the compounds M.29.6a) to M.29.6i) listed under M.29.6 are described in WO2012/029672, and M.29.6j) and M.29.6k) in WO2013/129688.
- the nematicide M.29.8 is known from WO2013/055584.
- the isoxazoline M.29.9.a) is described in WO2013/050317.
- the isoxazoline M.29.9.b) is described in WO2014/126208.
- the pyridalyl-type analogue M.29.10 is known from WO2010/060379.
- the carboxamides M.29.11.b) to M.29.11.h) are described in WO2010/018714, and the carboxamides M.29.11i) to M.29.11.p) in WO2010/127926.
- the pyridylthiazoles M.29.12.a) to M.29.12.c) are known from WO2010/006713, M.29.12.d) and M.29.12.e) are known from WO2012/000896, and M.29.12.f) to M.29.12.m) from WO2010/129497.
- the compounds M.29.14a) and M.29.14b) are known from WO2007/101369.
- the pyrazoles M.29.16.a) to M.29.16h) are described in WO2010/034737, WO2012/084670, and WO2012/143317, respectively, and the pyrazoles M.29.16i) and M.29.16j) are described in U.S.
- the pyridinylindazoles M.29.17a) to M.29.17.j) are described in WO2015/038503.
- the pyridylpyrazoles M.29.18a) to M.29.18d) are described in US2014/0213448.
- the isoxazoline M.29.19 is described in WO2014/036056.
- the isoxazoline M.29.20 is known from WO2014/090918.
- the carboxamide compound ii) of formula (Ia) and the pesticides of the above list M can be used together for the methods of the present invention.
- the mixture comprising the carboxamide compounds i) and ii) and the pesticides of the above list M can be used together for the methods of the present invention.
- fungicides described by common names, their preparation and their activity e.g. against harmful fungi is known (cf.: http://www.alanwood.net/pesticides/); these substances are commercially available.
- fungicides described by IUPAC nomenclature, their preparation and their pesticidal activity is also known (cf. Can. J. Plant Sci. 48(6), 587-94, 1968; EPA 141 317; EP-A 152 031; EP-A 226 917; EPA 243 970; EPA 256 503; EP-A 428 941; EP-A 532 022; EP-A 1 028 125; EP-A 1 035 122; EPA 1 201 648; EPA 1 122 244, JP 2002316902; DE 19650197; DE 10021412; DE 102005009458; U.S. Pat. No. 3,296,272; U.S. Pat. No.
- the carboxamide compound ii) of formula (Ia) and the fungicides of the above list with sections A) to K) can be used together for the methods of the present invention.
- the mixture comprising the carboxamide compounds i) and ii) and the fungicides of the above list with sections A) to K) can be used together for the methods of the present invention.
- carboxamide compound I preferably compound i) of formula (I), in mixtures together with one or more other active ingredients in the methods according to the present invention on cultivated plants, some combinations are especially preferred.
- a compound II selected from group of AChE-inhibitors as defined above is preferred, in particular selected from the group of carbamates, especially preferred carbofuran, benfuracarb or methomyl.
- a compound II selected from group of AChE-inhibitors as defined above is preferred, in particular selected from the group organophosphates, especially preferred chlorpyrifos and acephate.
- a compound II selected from group of GABA-gated chloride channel antagonists as defined above is preferred, in particular group fiproles, especially preferred ethiprole and fipronil.
- a compound II selected from group of Sodium channel modulators as defined above is preferred, in particular pyrethroids, especially preferred alpha-cypermethrin, bifenthrin, tefluthrin and cyhalothrin.
- a compound II selected from group of Neonicotinoids as defined above is preferred, in particular clothianidin, dinotefuran, imidacloprid, thiacloprid, or thiamethoxam.
- the compound II is selected from group of Nicotinic acetylcholine receptor allosteric activators and is preferably spinosad or spinetoram.
- the compound II is selected from group of Chloride channel activators and is preferably an avermectin.
- the compound II is selected from group of Selective homopteran feeding blockers and is preferably pymetrozine or flonicamid.
- the component II is selected from group of Mite growth inhibitors and is preferably etoxazole.
- the component II is selected from the group of Uncouplers of oxidative phosphorylation via disruption of the proton gradient and is preferably chlorfenapyr.
- the component II is selected from group of Inhibitors of the chitin biosynthesis type 1) and is preferably buprofezin.
- the component II is selected from group of Voltage-dependent sodium channel blockers) and is preferably metaflumizone or indoxacarb.
- the component II is selected from group of Inhibitors of the of acetyl CoA carboxylase and is preferably a Tetronic or Tetramic acid derivative, spirodiclofen, spiromesifen or spirotetramat.
- the compound II is selected from group of Mitochondrial complex II electron transport inhibitors and is preferably cyflumetofen.
- the compound II is selected from group of Ryanodine receptor-modulators and is preferably fubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole or cyantraniliprole.
- the compound II selected from group of Ryanodine receptor-modulators may also be selected from a compound listed in and coded as
- M.28.5a) to M.28.5d namely M.28.5a) N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5b) N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5c) N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyr
- carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro ⁇ methyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- a compound II selected from the group of the azoles is preferred, especially prochloraz, prothioconazole, tebuconazole and triticonazole, especially prothioconazole and triticonazole.
- a pesticidal mixture of the present invention preferred is a compound II selected from the group of benomyl, carbendazim, epoxiconazole, fluquinconazole, flutriafol, flusilazole, metconazole, prochloraz, prothioconazole, tebuconazole, triticonazole, pyraclostrobin, trifloxystrobin, boscalid, dimethomorph, penthiopyrad, dodemorph, famoxadone, fenpropimorph, proquinazid, pyrimethanil, tridemorph, maneb, mancozeb, metiram, thiram, chlorothalonil, dithianon, flusulfamide, metrafenone, fluxapyroxad (N-(3′,4′,5′ trifluorobiphenyl-2 yl)-3-difluoromethyl-1-methyl-1H-pyrazo
- metalaxyl, thiophanate-methyl, pyraclostrobin and fluxapyroxad is especially preferred.
- the mixture comprise as an additional component a compound against which the cultivated plant is resistant.
- carboxamide compound I preferably compound i) of formula (I
- the carboxamide compound I preferably compound i) of formula (I
- the use of mixtures of (1) the carboxamide compound I, preferably compound i) of formula (I), as component I, with (2) compounds II as defined herein as component II, in cultivated plants may display synergistic effects between the trait of the cultivated plant and the applied compounds.
- the present invention relates to methods for controlling pests of a cultivated plant, comprising the application of the carboxamide compound i) of formula (I), or a mixture of (1) the carboxamide compound i) of formula (I) as component I with (2) at least one compound II as component II as defined above to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth.
- the present invention further also relates to methods for controlling pests of a cultivated plant, comprising the application of the carboxamide compound ii) of formula (Ia), or a mixture of (1) the carboxamide compound ii) of formula (Ia) as component I with (2) at least one compound II as component II as defined above to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth.
- the present invention further also relates to methods for controlling pests of a cultivated plant, comprising the application of the mixture comprising the carboxamide compounds i) and ii), or a mixture of (1) the mixture comprising the carboxamide compounds i) and ii) as component I with (2) at least one compound II as component II as defined above to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth.
- health of a plant or “plant health” is defined as a condition of the plant and/or its products which is determined by several aspects alone or in combination with each other such as yield, plant vigor, quality and tolerance to abiotic and/or biotic stress.
- “increased yield” of a cultivated plant means that the yield of a product of the respective cultivated plant is increased via application of the carboxamide compound I, preferably compound i) of formula (I), or a mixture of the carboxamide compound I, preferably compound i) of formula (I) as component I with at least one compound II as component II by a measurable amount over the yield of the same product of the respective control plant produced under the same conditions and also under application of the carboxamide compound I, preferably compound i) of formula (I) or a mixture comprising the carboxamide compound I, preferably compound i) of formula (I) as component I with at least one compound II as component II.
- Increased yield can be characterized, among others, by the following improved properties of the cultivated plant: increased plant weight, increased plant height, increased biomass such as higher overall fresh weight (FW), increased number of flowers per plant, higher grain and/or fruit yield, more tillers or side shoots (branches), larger leaves, increased shoot growth, increased protein content, increased oil content, increased starch content, increased pigment content, increased chlorophyll content (chlorophyll content has a positive correlation with the plant's photosynthesis rate and accordingly, the higher the chlorophyll content the higher the yield of a plant)
- Gram and “fruit” are to be understood as any cultivated plant product which is further utilized after harvesting, e.g. fruits in the proper sense, vegetables, nuts, grains, seeds, wood (e.g. in the case of silviculture plants), flowers (e.g. in the case of gardening plants, ornamentals) etc., that is anything of economic value that is produced by the plant.
- the yield is increased by at least 4%, preferable by 5 to 10%, more preferable by 10 to 20%, or even 20 to 30%. In general, the yield increase may even be higher.
- the plant vigor becomes manifest in several aspects such as the general visual appearance.
- Improved plant vigor can be characterized, among others, by the following improved properties of the cultivated plant: improved vitality of the cultivated plant, improved plant growth, improved plant development, improved visual appearance, improved plant stand (less plant verse/lodging), improved emergence, enhanced root growth and/or more developed root system, enhanced nodulation, in particular rhizobial nodulation, bigger leaf blade, bigger size, increased plant height, increased tiller number, increased number of side shoots, increased number of flowers per plant, increased shoot growth, enhanced photosynthetic activity (e.g.
- Another indicator for the condition of the cultivated plant is the “quality” of a cultivated plant and/or its products.
- enhanced quality means that certain plant characteristics such as the content or composition of certain ingredients are increased or improved by a measurable or noticeable amount over the same factor of the control plant produced under the same conditions.
- Enhanced quality can be characterized, among others, by following improved properties of the cultivated plant or its product: increased nutrient content, increased protein content, increased content of fatty acids, increased metabolite content, increased carotenoid content, increased sugar content, increased amount of essential amino acids, improved nutrient composition, improved protein composition, improved composition of fatty acids, improved metabolite composition, improved carotenoid composition, improved sugar composition, improved amino acids composition, improved or optimal fruit color, improved leaf color, higher storage capacity, higher processability of the harvested products.
- Another indicator for the condition of the cultivated plant is the plants tolerance or resistance to biotic and/or abiotic stress factors.
- Biotic and abiotic stress can have harmful effects on cultivated plants. Biotic stress is caused by living organisms while abiotic stress is caused for example by environmental extremes.
- “enhanced tolerance or resistance to biotic and/or abiotic stress factors” means (1.) that certain negative factors caused by biotic and/or abiotic stress are diminished in a measurable or noticeable amount as compared to control plants exposed to the same conditions and (2.) that the negative effects are not diminished by a direct action of the carboxamide compound I, preferably compound i) of formula (I), or a mixture of (i) the carboxamide compound I, preferably compound i) of formula (I) as component I with (ii) at least one compound II as component II on the stress factors, e.g. by its insecticidal action, but rather by a stimulation of the cultivated plants' own defensive reactions against said stress factors.
- Biotic stress can be caused by living organisms, such as competing plants (for example weeds), microorganisms (such as phythopathogenic fungi and/or bacteria) and/or viruses.
- Negative factors caused by abiotic stress are also well-known and can often be observed as reduced plant vigor (see above), for example: dotted leaves, “burned leaves”, reduced growth, less flowers, less biomass, less crop yields, reduced nutritional value of the crops, later crop maturity, to give just a few examples.
- Abiotic stress can be caused for example by: extremes in temperature such as heat or cold (heat stress/cold stress), strong variations in temperature, temperatures unusual for the specific season, drought (drought stress), extreme wetness, high salinity (salt stress), radiation (for example by increased UV radiation due to the decreasing ozone layer), increased ozone levels (ozone stress), organic pollution (for example by phytho-toxic amounts of pesticides), inorganic pollution (for example by heavy metal contaminants).
- extremes in temperature such as heat or cold (heat stress/cold stress), strong variations in temperature, temperatures unusual for the specific season, drought (drought stress), extreme wetness, high salinity (salt stress), radiation (for example by increased UV radiation due to the decreasing ozone layer), increased ozone levels (ozone stress), organic pollution (for example by phytho-toxic amounts of pesticides), inorganic pollution (for example by heavy metal contaminants).
- Advantageous properties obtained especially from treated seeds, are e.g. improved germination and field establishment, better vigor and/or a more homogen field establishment.
- the above identified indicators for the health condition of a cultivated plant may be interdependent and may result from each other.
- an increased resistance to biotic and/or abiotic stress may lead to a better plant vigor, e.g. to better and bigger crops, and thus to an increased yield.
- a more developed root system may result in an increased resistance to biotic and/or abiotic stress.
- these interdependencies and interactions are neither all known nor fully understood and therefore the different indicators are described separately.
- the methods of the present invention effectuate an increased yield of a cultivated plant or its product.
- the methods of the present invention effectuate an increased vigor of a cultivated plant or its product.
- the methods of the present invention effectuate in an increased quality of a cultivated plant or its product.
- the methods of the present invention effectuate an increased tolerance and/or resistance of a cultivated plant or its product against biotic stress.
- the methods of the present invention effectuate an increased tolerance and/or resistance of a cultivated plant or its product against abiotic stress.
- the methods of the present invention increase the yield of cultivated plants.
- the methods of the present invention increase the yield of cultivated plants such as the plant weight and/or the plant biomass (e.g. overall fresh weight) and/or the grain yield and/or the number of tillers.
- the methods of the present invention increase the plant vigor of cultivated plants.
- the methods of the present invention increase the yield of cultivated plants.
- the methods of the present invention increase the yield of cultivated plants such as the plant weight and/or the plant biomass (e.g. overall fresh weight) and/or the grain yield and/or the number of tillers.
- the present invention also relates to methods increasing the plant health, in particular the yield of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound i) of formula (I), or a mixture of (1) the carboxamide compound i) of formula (I) as component I with (2) at least one compound II as component II to a cultivated plant, parts of such plant, its plant propagation material, or at its locus of growth.
- the present invention also relates to methods increasing the plant health, in particular the yield of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound ii) of formula (aI), or a mixture of (1) the carboxamide compound ii) of formula (Ia) as component I with (2) at least one compound II as component II to a cultivated plant, parts of such plant, its plant propagation material, or at its locus of growth.
- the present invention also relates to methods increasing the plant health, in particular the yield of a cultivated plant as compared to the respective non-modified control plant, comprising the application of a mixture comprising the carboxamide compounds i) and ii), or a mixture of (1) a mixture comprising the carboxamide compounds i) and ii) as component I with (2) at least one compound II as component II to a cultivated plant, parts of such plant, its plant propagation material, or at its locus of growth.
- the present invention also comprises plant propagation material, preferably seed, of a cultivated plant treated with the carboxamide compound i) of formula (I), or a mixture of the carboxamide compound i) of formula (I) as component I with at least one compound II as component
- the present invention further also comprises plant propagation material, preferably seed, of a cultivated plant treated with the carboxamide compound ii) of formula (Ia), or a mixture of the carboxamide compound ii) of formula (Ia) as component I with at least one compound II as component II.
- the present invention further also comprises plant propagation material, preferably seed, of a cultivated plant treated with a mixture comprising the carboxamide compounds i) and ii), or a mixture comprising the carboxamide compounds i) and ii) as component I together with at least one compound II as component II.
- cultivated plant(s) includes to “modified plant(s)” and “transgenic plant(s)”.
- the term “cultivated plants” refers to “modified plants”.
- the term “cultivated plants” refers to “transgenic plants”.
- “Modified plants” are those which have been modified by conventional breeding techniques.
- the term “modification” means in relation to modified plants a change in the genome, epigenome, transcriptome or proteome of the modified plant, as compared to the control, wild type, mother or parent plant whereby the modification confers a trait (or more than one trait) or confers the increase of a trait (or more than one trait) as listed below.
- the term “cultivated plant” refers to a plant, which has been modified by mutagenesis or genetic engineering.
- the modification may result in the modified plant to be a different, for example a new plant variety than the parental plant.
- Transgenic plants are those, which genetic material has been modified by the use of recombinant DNA techniques that under natural circumstances can not readily be obtained by cross breeding, mutations or natural recombination, whereby the modification confers a trait (or more than one trait) or confers the increase of a trait (or more than one trait) as listed below as compared to the wild-type plant.
- the term “transgenic plant” refers to a plant, which has been modified by genetic engineering.
- one or more genes have been integrated into the genetic material of a genetically modified plant in order to improve certain properties of the plant, preferably increase a trait as listed below as compared to the wild-type plant.
- Such genetic modifications also include but are not limited to targeted post-translational modification of protein(s), or to post-transcriptional modifications of oligo- or polypeptides e.g. by glycosylation or polymer additions such as prenylated, acetylated, phosphorylated or farnesylated moieties or PEG moieties.
- modification when referring to a transgenic plant or parts thereof is understood that the activity, expression level or amount of a gene product or the metabolite content is changed, e.g. increased or decreased, in a specific volume relative to a corresponding volume of a control, reference or wild-type plant or plant cell, including the de novo creation of the activity or expression.
- the activity of a polypeptide is increased or generated by expression or overexpresion of the gene coding for said polypeptide which confers a trait or confers the increase of a trait as listed below as compared to the control plant.
- expression or “gene expression” means the transcription of a specific gene or specific genes or specific genetic construct.
- expression or “gene expression” in particular means the transcription of a gene or genes or genetic construct into structural RNA (rRNA, tRNA), regulatory RNA (e.g. miRNA, RNAi, RNAa) or mRNA with or without subsequent translation of the latter into a protein.
- expression in particular means the transcription of a gene or genes or genetic construct into structural RNA (rRNA, tRNA) or mRNA with or without subsequent translation of the latter into a protein. In yet another embodiment it means the transcription of a gene or genes or genetic construct into mRNA.
- the process includes transcription of DNA and processing of the resulting mRNA product.
- increased expression or “overexpression” as used herein means any form of expression that is additional to the original wild-type expression level.
- polypeptide expression of a polypeptide is understood in one embodiment to mean the level of said protein or polypeptide, preferably in an active form, in a cell or organism.
- the activity of a polypeptide is decreased by decreased expression of the gene coding for said polypeptide which confers a trait or confers the increase of a trait as listed below as compared to the control plant.
- Reference herein to “decreased expression” or “reduction or substantial elimination” of expression is taken to mean a decrease in endogenous gene expression and/or polypeptide levels and/or polypeptide activity relative to control plants. It comprises further reducing, repressing, decreasing or deleting of an expression product of a nucleic acid molecule.
- reduction relate to a corresponding change of a property in an organism, a part of an organism such as a tissue, seed, root, tuber, fruit, leave, flower etc. or in a cell.
- change of a property it is understood that the activity, expression level or amount of a gene product or the metabolite content is changed in a specific volume or in a specific amount of protein relative to a corresponding volume or amount of protein of a control, reference or wild type.
- the overall activity in the volume is reduced, decreased or deleted in cases if the reduction, decrease or deletion is related to the reduction, decrease or deletion of an activity of a gene product, independent whether the amount of gene product or the specific activity of the gene product or both is reduced, decreased or deleted or whether the amount, stability or translation efficacy of the nucleic acid sequence or gene encoding for the gene product is reduced, decreased or deleted.
- reduction include the change of said property in only parts of the subject of the present invention, for example, the modification can be found in compartment of a cell, like an organelle, or in a part of a plant, like tissue, seed, root, leave, tuber, fruit, flower etc. but is not detectable if the overall subject, i.e. complete cell or plant, is tested.
- the “reduction”, “repression”, “decrease” or “deletion” is found cellular, thus the term “reduction, decrease or deletion of an activity” or “reduction, decrease or deletion of a metabolite content” relates to the cellular reduction, decrease or deletion compared to the wild type cell.
- the terms “reduction”, “repression”, “decrease” or “deletion” include the change of said property only during different growth phases of the organism used in the inventive process, for example the reduction, repression, decrease or deletion takes place only during the seed growth or during blooming.
- the terms include a transitional reduction, decrease or deletion for example because the used method, e.g. the antisense, RNAi, snRNA, dsRNA, siRNA, miRNA, ta-siRNA, cosuppression molecule, or ribozyme, is not stable integrated in the genome of the organism or the reduction, decrease, repression or deletion is under control of a regulatory or inducible element, e.g. a chemical or otherwise inducible promoter, and has therefore only a transient effect.
- a regulatory or inducible element e.g. a chemical or otherwise inducible promoter
- Reducing, repressing, decreasing or deleting of an expression product of a nucleic acid molecule in modified plants is known.
- Examples are canola i.e. double nill oilseed rape with reduced amounts of erucic acid and sinapins.
- Such a decrease can also be achieved for example by the use of recombinant DNA technology, such as antisense or regulatory RNA (e.g. miRNA, RNAi, RNAa) or siRNA approaches.
- antisense or regulatory RNA e.g. miRNA, RNAi, RNAa
- siRNA approaches e.g. RNAi, snRNA, dsRNA, siRNA, miRNA, ta-siRNA, cosuppression molecule, ribozyme, or antisense nucleic acid molecule
- a nucleic acid molecule conferring the expression of a dominant-negative mutant of a protein or a nucleic acid construct capable to recombine with and silence, inactivate, repress or reduces the activity of an endogenous gene may be used to decrease the activity of a polypeptide in a transgenic plant or parts thereof or a plant cell thereof used in one embodiment of the methods of the invention.
- transgenic plants with reduced, repressed, decreased or deleted expression product of a nucleic acid molecule are Carica papaya ( Papaya plants) with the event name X17-2 of the University of Florida, Prunus domestica (Plum) with the event name C5 of the United States Department of Agriculture—Agricultural Research Service, or those listed in rows T9-48 and T9-49 of table 9 below.
- plants with increased resistance to nematodes for example by reducing, repressing, decreasing or deleting of an expression product of a nucleic acid molecule, e.g. from the PCT publication WO 2008/095886.
- the reduction or substantial elimination is in increasing order of preference at least 10%, 20%, 30%, 40% or 50%, 60%, 70%, 80%, 85%, 90%, or 95%, 96%, 97%, 98%, 99% or more reduced compared to that of control plants.
- Reference herein to an “endogenous” gene not only refers to the gene in question as found in a plant in its natural form (i.e., without there being any human intervention), but also refers to that same gene (or a substantially homologous nucleic acid/gene) in an isolated form subsequently (re)introduced into a plant (a transgene).
- a transgenic plant containing such a transgene may encounter a substantial reduction of the transgene expression and/or substantial reduction of expression of the endogenous gene.
- control or “reference” are exchangeable and can be a cell or a part of a plant such as an organelle like a chloroplast or a tissue, in particular a plant, which was not modified or treated according to the herein described process according to the invention. Accordingly, the plant used as control or reference corresponds to the plant as much as possible and is as identical to the subject matter of the invention as possible. Thus, the control or reference is treated identically or as identical as possible, saying that only conditions or properties might be different which do not influence the quality of the tested property other than the treatment of the present invention.
- control or reference plants are wild-type plants.
- control or reference plants may refer to plants carrying at least one genetic modification, when the plants employed in the process of the present invention carry at least one genetic modification more than said control or reference plants.
- control or reference plants may be transgenic but differ from transgenic plants employed in the process of the present invention only by said modification contained in the transgenic plants employed in the process of the present invention.
- wild type or wild-type plants refers to a plant without said genetic modification. These terms can refer to a cell or a part of a plant such as an organelle like a chloroplast or a tissue, in particular a plant, which lacks said genetic modification but is otherwise as identical as possible to the plants with at least one genetic modification employed in the present invention. In a particular embodiment the “wild-type” plant is not transgenic.
- the wild type is identically treated according to the herein described process according to the invention.
- the person skilled in the art will recognize if wild-type plants will not require certain treatments in advance to the process of the present invention, e.g. non-transgenic wild-type plants will not need selection for transgenic plants for example by treatment with a selecting agent such as a herbicide.
- the control plant may also be a nullizygote of the plant to be assessed.
- nullizygote refers to a plant that has undergone the same production process as a transgenic, yet has lost the once acquired genetic modification (e.g. due to mendelian segregation) as the corresponding transgenic. If the starting material of said production process is transgenic, then nullizygotes are also transgenic but lack the additional genetic modification introduced by the production process.
- the purpose of wild-type and nullizygotes is the same as the one for control and reference or parts thereof. All of these serve as controls in any comparison to provide evidence of the advantageous effect of the present invention.
- any comparison is carried out under analogous conditions.
- analogous conditions means that all conditions such as, for example, culture or growing conditions, soil, nutrient, water content of the soil, temperature, humidity or surrounding air or soil, assay conditions (such as buffer composition, temperature, substrates, pathogen strain, concentrations and the like) are kept identical between the experiments to be compared.
- assay conditions such as buffer composition, temperature, substrates, pathogen strain, concentrations and the like.
- results can be normalized or standardized based on the control.
- the “reference”, “control”, or “wild type” is preferably a plant, which was not modified or treated according to the herein described process of the invention and is in any other property as similar to a plant, employed in the process of the present invention of the invention as possible.
- the reference, control or wild type is in its genome, transcriptome, proteome or metabolome as similar as possible to a plant, employed in the process of the present invention of the present invention.
- the term “reference-” “control-” or “wild-type-” plant relates to a plant, which is nearly genetically identical to the organelle, cell, tissue or organism, in particular plant, of the present invention or a part thereof preferably 90% or more, e.g.
- the “reference”, “control”, or “wild type” is a plant, which is genetically identical to the plant, cell, a tissue or organelle used according to the process of the invention except that the responsible or activity conferring nucleic acid molecules or the gene product encoded by them have been amended, manipulated, exchanged or introduced in the organelle, cell, tissue, plant, employed in the process of the present invention.
- the reference and the subject matter of the invention are compared after standardization and normalization, e.g. to the amount of total RNA, DNA, or protein or activity or expression of reference genes, like housekeeping genes, such as ubiquitin, actin or ribosomal proteins.
- the genetic modification carried in the organelle, cell, tissue, in particular plant used in the process of the present invention is in one embodiment stable e.g. due to a stable transgenic integration or to a stable mutation in the corresponding endogenous gene or to a modulation of the expression or of the behaviour of a gene, or transient, e.g. due to an transient transformation or temporary addition of a modulator such as an agonist or antagonist or inducible, e.g. after transformation with a inducible construct carrying a nucleic acid molecule under control of a inducible promoter and adding the inducer, e.g. tetracycline.
- a modulator such as an agonist or antagonist or inducible
- preferred plants from which “modified plants” and/or “transgenic plants” are be selected from the group consisting of cereals, such as maize (corn), wheat, barley sorghum, rice, rye, millet, triticale, oat, pseudocereals (such as buckwheat and quinoa), alfalfa, apples, banana, beet, broccoli, Brussels sprouts, cabbage, canola (rapeseed), carrot, cauliflower, cherries, chickpea, Chinese cabbage, Chinese mustard, collard, cotton, cranberries, creeping bentgrass, cucumber, eggplant, flax, grape, grapefruit, kale, kiwi, kohlrabi, melon, mizuna, mustard, papaya, peanut, pears, pepper, persimmons, pigeonpea, pineapple, plum, potato, raspberry, rutabaga, soybean, squash, strawberries, sugar beet, sugarcane, sunflower, sweet corn, tobacco, tomato, turnip, walnut, watermel
- alfalfa canola (rapeseed), cotton, rice, maize, cerals (such as wheat, barley, rye, oat), soybean, fruits and vegetables (such as potato, tomato, melon, papaya), pome fruits (such as apple and pear), vine, sugarbeet, sugarcane, rape, citrus fruits (such as citron, lime, orange, pomelo, grapefruit, and mandarin) and stone fruits (such as cherry, apricot and peach), most preferably from cotton, rice, maize, cerals (such as wheat, barley, rye, oat), sorghum, squash, soybean, potato, vine, pome fruits (such as apple), citrus fruits (such as citron and orange), sugarbeet, sugarcane, rape, oilseed rape and tomatoes utmost preferably from cotton, rice, maize, wheat, barley, rye, oat, soybean, potato, vine, apple, apple
- the cultivated plant is a gymnosperm plant, especially a spruce, pine or fir.
- the invention relates to methods and uses, wherein the carboxamide compound i) of formula (I) is applied in an application type which corresponds in each case to one row of Table AP-T.
- the invention relates to methods and uses, wherein the carboxamide compound i) of formula (I) as component I and at least one compound II as defined above as component II, are applied in an application type which corresponds in each case to one row of Table AP-T.
- the invention relates to methods and uses, wherein the carboxamide compound ii) of formula (Ia) is applied in an application type which corresponds in each case to one row of Table AP-T.
- the invention relates to methods and uses, wherein a mixture comprising the carboxamide compounds i) and ii) is applied in an application type which corresponds in each case to one row of Table AP-T.
- the cultivated plants are plants, which comprise at least one trait.
- the term “trait” refers to a property, which is present in the plant either by genetic engineering or by conventional breeding techniques. Each trait has to be assessed in relation to its respective control. Examples of traits are: herbicide tolerance, insect resistance by expression of bacterial toxins, fungal resistance or viral resistance or bacterial resistance, antibiotic resistance, stress tolerance, maturation alteration, content modification of chemicals present in the cultivated plant, preferably increasing the content of fine chemicals advantageous for applications in the field of the food and/or feed industry, the cosmetics industry and/or the pharmaceutical industry, modified nutrient uptake, preferably an increased nutrient use efficiency and/or resistance to conditions of nutrient deficiency, improved fiber quality, plant vigor, modified colour, fertility restoration, and male sterility.
- cultivadas plants may also comprise combinations of the aforementioned traits, e.g. they may be tolerant to the action of herbicides and express bacertial toxins.
- all cultivated plants may also provide combinations of the aforementioned properties, e.g. they may be tolerant to the action of herbicides and express bacertial toxins.
- plant refers to a cultivated plant.
- Tolerance to herbicides can be obtained by creating insensitivity at the site of action of the herbicide by expression of a target enzyme which is resistant to herbicide; rapid metabolism (conjugation or degradation) of the herbicide by expression of enzymes which inactivate herbicide; or poor uptake and translocation of the herbicide.
- Examples are the expression of enzymes which are tolerant to the herbicide in comparison to wild type enzymes, such as the expression of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), which is tolerant to glyphosate (see e.g. Heck et. al, Crop Sci. 45, 2005, 329-339; Funke et. al, PNAS 103, 2006, 13010-13015; U.S. Pat.
- EPSPS 5-enolpyruvylshikimate-3-phosphate synthase
- Gene constructs can be obtained, for example, from micro-organism or plants, which are tolerant to said herbicides, such as the Agrobacterium strain CP4 EPSPS which is resistant to glyphosate; Streptomyces bacteria which are resistance to glufosinate; Arabidopsis, Daucus carota, Pseudomonoas spp. or Zea grass with chimeric gene sequences coding for HDDP (see e.g. WO 1996/38567, WO 2004/55191); Arabidopsis thaliana which is resistant to protox inhibitors (see e.g. US 2002/0073443).
- said herbicides such as the Agrobacterium strain CP4 EPSPS which is resistant to glyphosate; Streptomyces bacteria which are resistance to glufosinate; Arabidopsis, Daucus carota, Pseudomonoas spp. or Zea grass with chimeric gene sequences coding for HD
- Tolerance to glyphosate can also be achieved by any one of the genes 2mepsps, epsps, gat4601, goxv247 or mepsps.
- Tolerance to glufosinate can be achieved by any one of the genes bar, pat or pat(syn).
- the herbicide tolerant plant can be selected from cereals such as wheat, barley, rye, oat; canola, sorghum, soybean, rice, oil seed rape, sugar beet, sugarcane, grapes, lentils, sunflowers, alfalfa, pome fruits; stone fruits; peanuts; coffee; tea; strawberries; turf; vegetables, such as tomatoes, potatoes, cucurbits and lettuce, more preferably, the plant is selected from soybean, maize (corn), rice, cotton, oilseed rape in particular canola, tomatoes, potatoes, sugarcane, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- cereals such as wheat, barley, rye, oat
- canola, sorghum soybean
- rice oil seed rape
- sugar beet sugarcane
- grapes lentils
- sunflowers alfalfa
- pome fruits stone fruits
- stone fruits peanuts
- coffee coffee
- the cultivated plant is selected from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize), Glycine max L. (soybean), Triticum aestivum (wheat), and Oryza sativa L. (rice), preferably from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize) and Glycine max L. (soybean).
- the cultivated plant is Glycine max L. (soybean).
- Examples of commercial available transgenic plants with tolerance to herbicides are the corn varieties “Roundup Ready Corn”, “Roundup Ready 2” (Monsanto), “Agrisure GT”, “Agrisure GT/CB/LL”, “Agrisure GT/RW”, “Agrisure 3000GT” (Syngenta), “YieldGard VT Rootworm/RR2” and “YieldGard VT Triple” (Monsanto) with tolerance to glyphosate; the corn varieties “Liberty Link” (Bayer), “Herculex I”, “Herculex RW”, “Herculex Xtra” (Dow, Pioneer), “Agrisure GT/CB/LL” and “Agrisure CB/LL/RW” (Syngenta) with tolerance to glufosinate; the soybean varieties “Roundup Ready Soybean” (Monsanto) and “Optimum GAT” (DuPont, Pioneer) with tolerance to glyphosate; the cotton varieties “Round
- transgenic plants with herbicide tolerance are commonly known, for instance alfalfa, apple, eucalyptus, flax, grape, lentils, oil seed rape, peas, potato, rice, sugar beet, sunflower, tobacco, tomatom turf grass and wheat with tolerance to glyphosate (see e.g. U.S. Pat. No. 5,188,642, U.S. Pat. No. 4,940,835, U.S. Pat. No. 5,633,435, U.S. Pat. No. 5,804,425, U.S. Pat. No. 5,627,061); beans, soybean, cotton, peas, potato, sunflower, tomato, tobacco, corn, sorghum and sugarcane with tolerance to dicamba (see e.g.
- Plants which are capable of synthesising one or more selectively acting bacterial toxins, comprise for example at least one toxin from toxin-producing bacteria, especially those of the genus Bacillus , in particular plants capable of synthesising one or more insecticidal proteins from Bacillus cereus or Bacillus popliae ; or insecticidal proteins from Bacillus thuringiensis , such as delta.-endotoxins, e.g. CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c, or vegetative insecticidal proteins (VIP), e.g.
- VIP vegetative insecticidal proteins
- toxins produced by animals such as scorpion toxins, arachnid toxins, wasp toxins and other insect-specific neurotoxins
- toxins produced by fungi such as Streptomycetes toxins, plant lectins, such as pea lectins, barley lectins or snowdrop lectins
- proteinase inhibitors such as trypsine inhibitors, serine protease inhibitors, patatin, cystatin, papain inhibitors
- steroid metabolism enzymes such as 3-hydroxysteroid
- a plant is capable of producing a toxin, lectin or inhibitor if it contains at least one cell comprising a nucleic acid sequence encoding said toxin, lectin, inhibitor or inhibitor producing enzyme, and said nucleic acid sequence is transcribed and translated and if appropriate the resulting protein processed and/or secreted in a constitutive manner or subject to developmental, inducible or tissue-specific regulation.
- delta.-endotoxins for example CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c, or vegetative insecticidal proteins (VIP), for example VIP1, VIP2, VIP3 or VIP3A, expressly also hybrid toxins, truncated toxins and modified toxins.
- Hybrid toxins are produced recombinantly by a new combination of different domains of those proteins (see, for example, WO 02/15701).
- a truncated toxin is a truncated Cry1A(b), which is expressed in the Bt11 maize from Syngenta Seed SAS, as described below.
- modified toxins one or more amino acids of the naturally occurring toxin are replaced.
- non-naturally present protease recognition sequences are inserted into the toxin, such as, for example, in the case of CryIIIA055, a cathepsin-D-recognition sequence is inserted into a CryIIIA toxin (see WO 2003/018810).
- Examples of such toxins or transgenic plants capable of synthesising such toxins are disclosed, for example, in EP-A-0 374 753, WO 93/07278, WO 95/34656, EP-A-0 427 529, EP-A451 878 and WO 2003/052073.
- genes conferring resistance to coleopteran insects include cry34Ab1, cry35 Ab1, cry3A, cry3Bb1, dvsnf7, and mcry3A.
- genes conferring resistance to lepidopteran insects include cry1A, cry1A.105, cry1Ab, cry1Ab-Ac, cry1Ac, cry1C, cry1F, cry1Fa2, cry2Ab2, cry2Ae, cry9c, mocry1F, pinII, vip3A(a), and vip3Aa20.
- Cry1-type deoxyribonucleic acids and their preparation are known, for example, from WO 95/34656, EP-A0 367 474, EP-A-0 401 979 and WO 1990/13651.
- the toxin contained in the transgenic plants imparts to the plants tolerance to harmful insects.
- insects can occur in any taxonomic group of insects, but are especially commonly found in the beetles (Coleoptera), two-winged insects (Diptera) and butterflies (Lepidoptera).
- the plant capable of expression of bacterial toxins is selected from cereals such as wheat, barley, rye, oat; canola, cotton, eggplant, lettuce, sorghum, soybean, rice, oil seed rape, sugar beet, sugarcane, grapes, lentils, sunflowers, alfalfa, pome fruits; stone fruits; peanuts;
- cereals such as wheat, barley, rye, oat; canola, cotton, eggplant, lettuce, sorghum, soybean, rice, oil seed rape, sugar beet, sugarcane, grapes, lentils, sunflowers, alfalfa, pome fruits; stone fruits; peanuts;
- the plant is selected from cotton, soybean, maize (corn), rice, tomatoes, potatoes, oilseed rape and cereals such as wheat, barley, rye and oat, most preferably from cotton, soybean, maize, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat. More preferably, the cultivated plant is selected from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize), Glycine max L. (soybean), Triticum aestivum (wheat), and Oryza sativa L.
- the cultivated plant is Glycine max L. (soybean).
- Examples of commercial available transgenic plants capable of expression of bacterial toxins are the corn varieties “YieldGard corn rootworm” (Monsanto), “YieldGard VT” (Monsanto), “Herculex RW” (Dow, Pioneer), “Herculex Rootworm” (Dow, Pioneer) and “Agrisure CRW” (Syngenta) with resistance against corn rootworm; the corn varieties “YieldGard corn borer” (Monsanto), “YieldGard VT Pro” (Monsanto), “Agrisure CB/LL” (Syngenta), “Agrisure 3000GT” (Syngenta), “Hercules I”, “Hercules II” (Dow, Pioneer), “KnockOut” (Novartis), “NatureGard” (Mycogen) and “StarLink” (Aventis) with resistance against corn borer, the corn varieties “Herculex I” (Dow, Pioneer) and “Herculex Xtra” (Dow,
- transgenic plants with insect resistance are commonly known, such as yellow stemborer resistant rice (see e.g. Molecular Breeding, Volume 18, 2006, Number 1), lepidopteran resistant lettuce (see e.g. U.S. Pat. No. 5,349,124), resistant soybean (see e.g. U.S. Pat. No. 7,432,421) and rice with resistance against Lepidopterans, such as rice stemborer, rice skipper, rice cutworm, rice caseworm, rice leaffolder and rice armyworm (see e.g. WO 2001021821).
- the methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
- plants which are capable of synthesising antipathogenic substances are selected from soybean, maize (corn), rice, tomatoes, potato, banana, papaya, tobacco, grape, plum and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, tomatoes, potato, banana, papaya, oil seed rape, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- Plants which are capable of synthesising antipathogenic substances having a selective action are for example plants expressing the so-called “pathogenesis-related proteins” (PRPs, see e.g. EP-A-0 392 225) or so-called “antifungal proteins” (AFPs, see e.g. U.S. Pat. No. 6,864,068).
- PRPs pathogenesis-related proteins
- AFPs antifungal proteins
- a wide range of antifungal proteins with activity against plant pathogenic fungi have been isolated from certain plant species and are common knowledge. Examples of such antipathogenic substances and transgenic plants capable of synthesising such antipathogenic substances are known, for example, from EP-A-0 392 225, WO 93/05153, WO 95/33818, and EP-A-0 353 191.
- Transgenic plants which are resistant against fungal, viral and bacterial pathogens are produced by introducing plant resistance genes.
- Numerous resistant genes have been identified, isolated and were used to improve plant resistant, such as the N gene which was introduced into tobacco lines that are susceptible to Tobacco Mosaic Virus (TMV) in order to produce TMV-resistant tobacco plants (see e.g. U.S. Pat. No. 5,571,706), the Prf gene, which was introduced into plants to obtain enhanced pathogen resistance (see e.g. WO 199802545) and the Rps2 gene from Arabidopsis thaliana , which was used to create resistance to bacterial pathogens including Pseudomonas syringae (see e.g. WO 199528423).
- Plants exhibiting systemic acquired resistance response were obtained by introducing a nucleic acid molecule encoding the TIR domain of the N gene (see e.g. U.S. Pat. No. 6,630,618).
- Further examples of known resistance genes are the Xa21 gene, which has been introduced into a number of rice cultivars (see e.g. U.S. Pat. No. 5,952,485, U.S. Pat. No. 5,977,434, WO 1999/09151, WO 1996/22375), the Rcg1 gene for colletotrichum resistance (see e.g. US 2006/225152), the prp1 gene (see e.g. U.S. Pat. No.
- the PIP gene to introduce a broad resistant to viruses, such as potato virus X (PVX), potato virus Y (PVY), potato leafroll virus (PLRV) (see e.g. EP 0707069) and genes such as Arabidopsis N116, ScaM4 and ScaM5 genes to obtain fungal resistance (see e.g. U.S. Pat. No. 6,706,952 and EP 1018553).
- viruses such as potato virus X (PVX), potato virus Y (PVY), potato leafroll virus (PLRV)
- PLRV potato leafroll virus
- genes such as Arabidopsis N116, ScaM4 and ScaM5 genes to obtain fungal resistance (see e.g. U.S. Pat. No. 6,706,952 and EP 1018553).
- the methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
- Antipathogenic substances which can be expressed by such transgenic plants include, for example, ion channel blockers, such as blockers for sodium and calcium channels, for example the viral KP1, KP4 or KP6 toxins; stilbene synthases; bibenzyl synthases; chitinases; glucanases; the so-called “pathogenesis-related proteins” (PRPs; see e.g. EP-A-0 392 225); antipathogenic substances produced by microorganisms, for example peptide antibiotics or heterocyclic antibiotics (see e.g. WO 1995/33818) or protein or polypeptide factors involved in plant pathogen defense (so-called “plant disease resistance genes”, as described in WO 2003/000906).
- ion channel blockers such as blockers for sodium and calcium channels, for example the viral KP1, KP4 or KP6 toxins
- stilbene synthases such as the viral KP1, KP4 or KP6 toxins
- bibenzyl synthases such as
- Antipathogenic substances produced by the plants are able to protect the plants against a variety of pathogens, such as fungi, viruses and bacteria.
- Useful plants of elevated interest in connection with present invention are cereals, such as wheat, barley, rye and oat; soybean; maize; rice; alfalfa, cotton, sugar beet, sugarcane, tobacco, potato, banana, oil seed rape; pome fruits; stone fruits; peanuts; coffee; tea; strawberries; turf; vines and vegetables, such as tomatoes, potatoes, cucurbits, papaya, melon, lenses and lettuce, more preferably selected from soybean, maize (corn), alfalfa, cotton, potato, banana, papaya, rice, tomatoes and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, potato, tomato, oilseed rape, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- Transgenic plants with resistance against fungal pathogens are, for examples, soybeans with resistance against Asian soybean rust (see e.g. WO 2008/017706); plants such as alfalfa, corn, cotton, sugar beet, oileed, rape, tomato, soybean, wheat, potato and tobacco with resistance against Phytophtora infestans (see e.g. U.S. Pat. No. 5,859,332, U.S. Pat. No.
- WO 1999064600 plants such as rice, wheat, barley, rye, corn, oats, potato, melon, soybean and sorghum with resistance against fusarium diseases, such as Fusarium graminearum, Fusarium sporotrichioides, Fusarium lateritium, Fusarium pseudograminearum Fusarium sambucinum, Fusarium culmorum, Fusarium poae, Fusarium acuminatum, Fusarium equiseti (see e.g. U.S. Pat. No.
- plants such as corn, soybean, cereals (in particular wheat, rye, barley, oats, rye, rice), tobacco, sorghum, sugarcane and potatoes with broad fungal resistance (see e.g. U.S. Pat. No. 5,689,046, U.S. Pat. No. 6,706,952, EP 1018553 and U.S. Pat. No. 6,020,129).
- Transgenic plants with resistance against bacterial pathogens and which are covered by the present invention are, for examples, rice with resistance against Xylella fastidiosa (see e.g. U.S. Pat. No. 6,232,528); plants, such as rice, cotton, soybean, potato, sorghum, corn, wheat, balrey, sugarcane, tomato and pepper, with resistance against bacterial blight (see e.g. WO 2006/42145, U.S. Pat. No. 5,952,485, U.S. Pat. No. 5,977,434, WO 1999/09151, WO 1996/22375); tomato with resistance against Pseudomonas syringae (see e.g. Can. J. Plant Path., 1983, 5: 251-255).
- Transgenic plants with resistance against viral pathogens are, for examples, stone fruits, such as plum, almond, apricot, cherry, peach, nectarine, with resistance against plum pox virus (PPV, see e.g. US PP15,154Ps, EP 0626449); potatoes with resistance against potato virus Y (see e.g. U.S. Pat. No. 5,968,828); plants such as potato, tomato, cucumber and leguminosaes which are resistant against tomato spotted wilt virus (TSWV, see e.g. EP 0626449, U.S. Pat. No. 5,973,135); corn with resistance against maize streak virus (see e.g. U.S. Pat. No.
- deregulated orcommercially available transgenic plants with modified genetic material capable of expression of antipathogenic substances are the following plants: Carica papaya (papaya), Event: 55-1/63-1; Georgia University, Carica papaya (Papaya); Event: (X17-2); University of Florida, Cucurbita pepo (Squash); Event: (CZW-3); Asgrow (USA); Seminis Vegetable Inc. (Canada), Cucurbita pepo (Squash); Event: (ZW20); Upjohn (USA); Seminis Vegetable Inc. (Canada), Prunus domestica (Plum); Event: (C5); United States Department of Agriculture—Agricultural Research Service, Solanum tuberosum L.
- Transgenic plants with resistance against nematodes and which may be used in the methods of the present invention are, for examples, soybean plants with resistance to soybean cyst nematodes.
- U.S. Pat. Nos. 5,589,622 and 5,824,876 are directed to the identification of plant genes expressed specifically in or adjacent to the feeding site of the plant after attachment by the nematode.
- transgenic plants with reduced feeding structures for parasitic nematodes e.g. plants resistant to herbicides except of those parts or those cells that are nematode feeding sites and treating such plant with a herbicide to prevent, reduce or limit nematode feeding by damaging or destroying feeding sites (e.g. U.S. Pat. No. 5,866,777).
- RNAi to target essential nematode genes has been proposed, for example, in PCT Publication WO 2001/96584, WO 2001/17654, US 2004/0098761, US 2005/0091713, US 2005/0188438, US 2006/0037101, US 2006/0080749, US 2007/0199100, and US 2007/0250947.
- Transgenic nematode resistant plants have been disclosed, for example in the PCT publications WO 2008/095886 and WO 2008/095889.
- the naturally occurring bacterial nptII gene expresses the enzyme that blocks the effects of the antibiotics kanamycin and neomycin.
- the ampicillin resistance gene ampR also known as blaTEM1
- ampR is derived from the bacterium Salmonella paratyphi and is used as a marker gene in the transformation of micro-organisms and plants. It is responsible for the synthesis of the enzyme beta-lactamase, which neutralises antibiotics in the penicillin group, including ampicillin.
- Transgenic plants with resistance against antibiotics are, for examples potato, tomato, flax, canola, oilseed rape and corn (see e.g.
- Plant Cell Reports 20, 2001, 610-615. Trends in Plant Science, 11, 2006, 317-319. Plant Molecular Biology, 37, 1998, 287-296. Mol Gen Genet., 257, 1998, 606-13.). Plant Cell Reports, 6, 1987, 333-336. Federal Register (USA), Vol. 60, No. 113, 1995, page 31139. Federal Register (USA), Vol. 67, No. 226, 2002, page 70392. Federal Register (USA), Vol. 63, No. 88, 1998, page 25194. Federal Register (USA), Vol. 60, No. 141, 1995, page 37870. Canadian Food Inspection Agency, FD/OFB-095-264-A, October 1999, FD/OFB-099-127-A, October 1999.
- the plant is selected from soybean, maize (corn), rice, cotton, oilseed rape, potato, sugarcane, alfalfa, tomatoes and cereals, such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, oilseed rape, tomato, potato, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- Plants which are tolerant to stress conditions are plants, which show increased tolerance to abiotic stress conditions such as drought, high salinity, high light intensities, high UV irradiation, chemical pollution (such as high heavy metal concentration), low or high temperatures, limited supply of nutrients (i.e. nitrogen, phosphorous) and population stress.
- abiotic stress conditions such as drought, high salinity, high light intensities, high UV irradiation, chemical pollution (such as high heavy metal concentration), low or high temperatures, limited supply of nutrients (i.e. nitrogen, phosphorous) and population stress.
- transgenic plants with resistance to stress conditions are selected from rice, corn, soybean, sugarcane, alfalfa, wheat, tomato, potato, barley, rapeseed, beans, oats, sorghum and cotton with tolerance to drought (see e.g.
- the plant is selected from soybean, maize (corn), rice, cotton, sugarcane, alfalfa, sugar beet, potato, oilseed rape, tomatoes and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, oilseed rape, tomato, potato, sugarcane, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- Altered maturation properties are for example delayed ripening, delayed softening and early maturity.
- transgenic plants with modified maturation properties are, selected from tomato, melon, raspberry, strawberry, muskmelon, pepper and papaya with delayed ripening (see e.g. U.S. Pat. No. 5,767,376, U.S. Pat. No. 7,084,321, U.S. Pat. No. 6,107,548, U.S. Pat. No. 5,981,831, WO 1995035387, U.S. Pat. No. 5,952,546, U.S. Pat. No. 5,512,466, WO 1997001952, WO 1992/008798, Plant Cell. 1989, 53-63. Plant Molecular Biology, 50, 2002).
- the plant is selected from fruits, such as tomato, vine, melon, papaya, banana, pepper, raspberry and strawberry; stone fruits, such as cherry, apricot and peach; pome fruits, such as apple and pear; and citrus fruits, such as citron, lime, orange, pomelo, grapefruit, and mandarin; more preferably from tomato, vine, apple, banana, orange and strawberry, most preferably tomatoes.
- fruits such as tomato, vine, melon, papaya, banana, pepper, raspberry and strawberry
- stone fruits such as cherry, apricot and peach
- pome fruits such as apple and pear
- citrus fruits such as citron, lime, orange, pomelo, grapefruit, and mandarin
- tomato, vine, apple, banana, orange and strawberry most preferably tomatoes.
- Content modification is synthesis of modified chemical compounds (if compared to the corresponding control plant) or synthesis of enhanced amounts of chemical (if compounds compared to the corresponding control plant) and corresponds to an increased or reduced amount of vitamins, amino acids, proteins and starch, different oils and a reduced amount of nicotine.
- soybean varieties “Vistive II” and “Visitive III” with low-linolenic/medium oleic content are the soybean varieties “Vistive II” and “Visitive III” with low-linolenic/medium oleic content; the corn variety “Mavera high-value corn” with increased lysine content; and the soybean variety “Mavera high value soybean” with yielding 5% more protein compared to conventional varieties when processed into soybean meal.
- Further transgenic plants with altered content are, for example, potato and corn with modified amylopectin content (see e.g. U.S. Pat. No. 6,784,338, US 20070261136); canola, corn, cotton, grape, catalpa, cattail, rice, soybean, wheat, sunflower, balsam pear and vernonia with a modified oil content (see e.g. U.S.
- EP 0929685, WO 1997041239) tomato with increased free amino acid contents, such as asparagine, aspartic acid, serine, threonine, alanine, histidine and glutamic acid (see e.g. U.S. Pat. No. 6,727,411); corn with enhanced amino acid content (see e.g. WO 05077117); potato, corn and rice with modified starch content (see e.g. WO 1997044471 and U.S. Pat. No. 7,317,146); tomato, corn, grape, alfalfa, apple, beans and peas with modified flavonoid content (see e.g.
- the plant is selected from soybean, maize (corn), rice, cotton, sugarcane, potato, tomato, oilseed rape, flax and cereals such as wheat, barley, rye and oat, most preferably soybean, maize (corn), rice, oilseed rape, potato, tomato, cotton, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- transgenic plants with enhanced nitrogen assimilatory and utilization capacities are selected from for example, canola, corn, wheat, sunflower, rice, tobacco, soybean, cotton, alfalfa, tomato, wheat, potato, sugar beet, sugar cane and rapeseed (see e.g. WO 1995/009911, WO 1997/030163, U.S. Pat. No. 6,084,153, U.S. Pat. No. 5,955,651 and U.S. Pat. No. 6,864,405). Plants with improved phosphorous uptake are, for example, tomato and potato (see e.g. U.S. Pat. No.
- the plant is selected from soybean, maize (corn), rice, cotton, sugarcane, alfalfa, potato, oilseed rape and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, oilseed rape, tomato, potato, vine, apple, pear, citron, orange and cereals such as wheat, barley.
- Transgenic plants with male sterility are preferably selected from canola, corn, tomato, rice, Indian mustard, wheat, soybean and sunflower (see e.g. U.S. Pat. No. 6,720,481, U.S. Pat. No. 6,281,348, U.S. Pat. No. 5,659,124, U.S. Pat. No. 6,399,856, U.S. Pat. No. 7,345,222, U.S. Pat. No. 7,230,168, U.S. Pat. No. 6,072,102, EP1 135982, WO 2001/092544 and WO 1996/040949).
- the methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
- the plant is selected from soybean, maize (corn), rice, cotton, oilseed rape, tomato, potato, vine, apple, pear, citron, orange and cereals such as wheat, barley.
- Plants, which produce higher quality fiber are e.g. transgenic cotton plants.
- the such improved quality of the fiber is related to improved micronaire of the fiber, increased strength, improved staple length, improved length unifomity and color of the fibers (see e.g. WO 1996/26639, U.S. Pat. No. 7,329,802, U.S. Pat. No. 6,472,588 and WO 2001/17333).
- the methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
- cultivadas plants may comprise one or more traits, e.g. selected from the group consisting of herbicide tolerance, insect resistance, fungal resistance, viral resistance, bacterial resistance, stress tolerance, maturation alteration, content modification, modified nutrient uptake and male sterility (see e.g. WO 2005033319 and U.S. Pat. No. 6,376,754).
- traits e.g. selected from the group consisting of herbicide tolerance, insect resistance, fungal resistance, viral resistance, bacterial resistance, stress tolerance, maturation alteration, content modification, modified nutrient uptake and male sterility (see e.g. WO 2005033319 and U.S. Pat. No. 6,376,754).
- Examples of commercial available transgenic plants with two combined properties are the corn varieties “YieldGard Roundup Ready” and YieldGard Roundup Ready 2′′ (Monsanto) with glyphosate tolerance and resistance to corn borer; the corn variety “Agrisure CB/LL” (Syntenta) with glufosinate tolerance and corn borer resistance; the corn variety “Yield Gard VT Rootworm/RR2” with glyphosate tolerance and corn rootworm resistance; the corn variety “Yield Gard VT Triple” with glyphosate tolerance and resistance against corn rootworm and corn borer; the corn variety “Herculex I” with glufosinate tolerance and lepidopteran resistance (Cry1F), i.e.
- Examples of commercial available transgenic plants with three traits are the corn variety “Herculex I/Roundup Ready 2” with glyphosate tolerance, gluphosinate tolerance and lepidopteran resistance (Cry1F), i.e. against western bean cutworm, corn borer, black cutworm and fall armyworm; the corn variety “YieldGard Plus/Roundup Ready 2” (Monsanto) with glyphosate tolerance, corn rootworm resistance and corn borer resistance; the corn variety “Agrisure GT/CB/LL” (Syngenta) with tolerance to glyphosate tolerance, tolerance to gluphosinate and corn borer resistance; the corn variety “Herculex Xtra” (Dow, Pioneer) with glufosinate tolerance and lepidopteran resistance (Cry1F+Cry34/35Ab1), i.e.
- the commercial transgenic plant is a soybean variety with glyphosate tolerance and lepidopteran resistance, preferably with one trait of glyphosate tolerance and two traits of lepidopteran resistance.
- the glyphosate tolerance is through expression of the EPSPS encoding gene from A. tumefaciens strain CP4, more preferably it is based on the transgenic event MON89788 (see A1-14, T1-100).
- the lepidopteran resistance is a resistance to lepidopteran pests of soybean, preferably through expression of the Cry1AC encoding gene from B. thuringiensis , preferably against velvetbean caterpillar ( Anticarsia gemmatalis ) and soybean looper ( Pseudoplusia includens ), more preferably it is based on the transgenic event MON87701.
- the glyphosate tolerance is based on the transgenic event MON89788 and the trait of lepidopteran resistance is achieved through expression of the Cry1AC encoding gene from B. thuringiensis , preferably against velvetbean caterpillar ( Anticarsia gemmatalis ) and soybean looper ( Pseudoplusia includens ), more preferably based on the transgenic event MON87701.
- the commercial transgenic plant is “Intacta RR2 PRO” soybean (Monsanto) which claims to offer tolerance to glyphosate herbicide and protection against major soybean pests (velvetbean caterpilar, soybean looper, soybean budborer, bean shoot borer, bollworm, corn stalk borer, Helicoverpa , e.g. Helicoverpa armigera ), along with increased yield potential.
- the commercial transgenic plant is a soybean variety selected from “Roundup Ready 2 Yield”, “Intacta RR2 Pro” and “Vistive Gold” (all Monsanto), or “Stearidonic Acid (SDA) Omega-3” (higher content of SDA in soybean, Monsanto).
- the trait is Bacillus thuringiensis Cry1A.105 and cry2Ab2 and Vector PV-GMIR13196, for Mon87751 soybean (Monsanto).
- the commercial transgenic plant is a corn variety which has aboveground insect protection from “Genuity VT Triple PRO” or “Herculex Xtra” or both of them, and herbicide tolerance from “Roundup Ready 2” and Liberty Link, preferably corn varieties selected from “Genuity SmartStax”, “Genuity VT Triple PRO” and “Genuity VT Double PRO” (all Monsanto), optionally as RIB (refuge-in-bag) solution.
- the commercial transgenic corn plant variety has a drought tolerance trait, preferably “Genuity DroughtGard”.
- the trait is double-stranded ribonucleic acid (dsRNA), Bacillus thuringiensis Cry3Bb1 protein and vector PV-ZMIR10871 for MON87411 corn.
- the commercial transgenic plant is a cotton variety selected from “Bollgard II” (insect protection), “Roundup Ready Flex” (herbicide tolerance) and “Bollgard II with Roundup Ready Flex” (both), all Monsanto.
- the cultivated plants are plants, which comprise at least one trait selected from herbicide tolerance, insect resistance by expression of bacertial toxins, fungal resistance or viral resistance or bacterial resistance by expression of antipathogenic substances, stress tolerance, content modification of chemicals present in the cultivated plant compared to the corresponding control plant.
- the cultivated plants are plants, which are tolerant to the action of herbicides and plants, which express bacterial toxins, which provides resistance against animal pests (such as insects or arachnids or nematodes), wherein the bacterial toxin is preferably a toxin from Bacillus thuriginensis .
- the plant is preferably selected from cotton, rice, maize, wheat, barley, rye, oat, soybean, potato, vine, apple, pear, citron and orange.
- the plant is soybean.
- the invention relates to a method for controlling pests and/or increasing the plant health of a cultivated plant with at least one modification as compared to the respective non-modified control plant, wherein the plant is soybean, which method comprises applying the carboxamide compound i) of formula (I), or a mixture of (1) the carboxamide compound i) of formula (I) as component I with (2) at least one compound II as component II.
- the invention relates to a method for controlling pests and/or increasing the plant health of a cultivated plant with at least one modification as compared to the respective non-modified control plant, wherein the plant is soybean, which method comprises applying the carboxamide compound ii) of formula (Ia), or a mixture of (1) the carboxamide compound ii) of formula (Ia) as component I with (2) at least one compound II as component II.
- the invention relates to a method for controlling pests and/or increasing the plant health of a cultivated plant with at least one modification as compared to the respective non-modified control plant, wherein the plant is soybean, which method comprises applying a mixture comprising the carboxamide compounds i) and ii), or a mixture of (1) a mixture comprising the carboxamide compounds i) and ii) as component I with (2) at least one compound II as component II.
- the cultivated plants are plants, which are tolerant to the action of herbicides. Further guidance for specific combinations within this utmost preferred embodiment can be found in tables 1, 2, 14 and tables A, B and C.
- the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise a herbicide III, to which the plant is tolerant.
- the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise a herbicide III, to which the plant is tolerant.
- the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) the mixture comprising the carboxide compounds i) and ii) with (2) at least one compound II may additionally comprise a herbicide III, to which the plant is tolerant.
- the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise glyphosate.
- the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise glyphosate.
- the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise glyphosate.
- the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (i) the carboxamide compound i) of formula (I) with (ii) at least one compound II may additionally comprise glufonisate.
- the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise glufonsinate.
- the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise glufonsinate.
- the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (i) the carboxamide compound i) of formula (I) with (ii) at least one compound II may additionally comprise at least one imidazolinone herbicide.
- the imidazolinone herbicide is selected from imazamox, imazethapyr, imazapic, imazapyr, imazamethabenz or imazaquin.
- the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise at least one imidazolinone herbicide.
- the imidazolinone herbicide is selected from imazamox, imazethapyr, imazapic, imazapyr, imazamethabenz or imazaquin.
- the cultivated plant is a cultivated plant tolerant to a imidazolinone herbicide
- the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise at least one imidazolinone herbicide.
- the imidazolinone herbicide is selected from imazamox, imazethapyr, imazapic, imazapyr, imazamethabenz or imazaquin.
- the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise dicamba.
- the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise dicamba.
- the cultivated plant is a cultivated plant tolerant to dicamba
- the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise dicamba.
- the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise sethoxidim.
- the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise sethoxidim.
- the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise sethoxidim.
- the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise cyloxidim.
- the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise cycloxidim.
- the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise cycloxidim.
- the present invention also relates to ternary mixtures, comprising the carboxamide compound i) of formula (I), an insecticide II and a herbicide III.
- the present invention also relates to ternary mixtures, comprising the carboxamide compound ii) of formula (Ia), an insecticide II and a herbicide III.
- the present invention also relates to ternary mixtures, comprising the mixture comprising the carboxamide compounds i) and ii), an insecticide II and a herbicide III.
- the present invention also relates to ternary mixtures comprising two insecticides and a fungicide.
- the present invention also relates to ternary mixtures comprising two fungicides and one insecticide.
- the present invention also relates to ternary mixtures comprising an insectide, a fungicide and a herbicide.
- mixture partners may be especially preferred.
- that compound II is preferably selected from teflubenzuron, chlorefenapyr or from the class of diamides
- mixtures wherein the at least one compound II is teflubenzuron can be preferred.
- mixtures, wherein the at least one compound II is chlorfenapyr can be preferred.
- mixtures wherein the at least one compound II is a ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-
- the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole
- the mixtures for seed treatment application comprising at least one other active compound II as component II, that compound II is preferably selected from thiamethoxam, fipronil or from the class of diamides
- mixtures wherein the at least one compound II is thiamethoxam can be preferred.
- mixtures, wherein the at least one compound II is fipronil can be preferred.
- mixtures wherein the at least one compound II is a ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-
- the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole
- the cultivated plants are plants, which comprise at least one trait selected from herbicide tolerance, insect resistance for example by expression of one or more bacterial toxins, fungal resistance or viral resistance or bacterial resistance by expression of one or more antipathogenic substances, stress tolerance, nutrient uptake, nutrient use efficiency, content modification of chemicals present in the cultivated plant compared to the corresponding control plant.
- the cultivated plants are plants, which comprise at least one trait selected from herbicide tolerance, insect resistance by expression of one or more bacterial toxins, fungal resistance or viral resistance or bacterial resistance by expression of one or more antipathogenic substances, stress tolerance, content modification of one or more chemicals present in the cultivated plant compared to the corresponding control plant.
- the cultivated plants are plants, which are tolerant to the action of herbicides and plants, which express one or more bacterial toxins, which provides resistance against one or more animal pests (such as insects or arachnids or nematodes), wherein the bacterial toxin is preferably a toxin from Bacillus thuriginensis .
- the cultivated plant is preferably selected from soybean, maize (corn), rice, cotton, sugarcane, alfalfa, potato, oilseed rape, tomatoes and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), cotton, rice and cereals such as wheat, barley, rye and oat.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant is a plant, which is rendered tolerant to herbicides, more preferably to herbicides such as glutamine synthetase inhibitors, 5-enol-pyrovyl-shikimate-3-phosphate-synthase inhibitors, acetolactate synthase (ALS) inhibitors, protoporphyrinogen oxidase (PPO) inhibitors, auxine type herbicides, most preferably to herbicides such as glyphosate, glufosinate, imazapyr, imazapic, imazamox, imazethapyr, imazaquin, imazamethabenz methyl, dicamba and 2,4-
- herbicides such
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a plant, which is rendered tolerant to herbicides, more preferably to herbicides such as glutamine synthetase inhibitors, 5-enol-pyrovyl-shikimate-3-phosphate-synthase inhibitors, acetolactate synthase (ALS) inhibitors, protoporphyrinogen oxidase (PPO) inhibitors, auxine type herbicides, most preferably to herbicides such as glyphosate, glufosinate, imazapyr, imazapic, imazamox, imazethapyr, imazaquin, imazamethabenz methyl, dicamba and 2,4-D
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant is a plant, which is rendered tolerant to herbicides, more preferably to herbicides such as glutamine synthetase inhibitors, 5-enol-pyrovyl-shikimate-3-phosphate-synthase inhibitors, acetolactate synthase (ALS) inhibitors, protoporphyrinogen oxidase (PPO) inhibitors, auxine type herbicides, most preferably to herbicides such as glyphosate, glufosinate, imazapyr, imazapic, imazamox, imazethapyr, imazaquin, imazamethabenz methyl, dic
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant is a plant, which express at least one insecticidal toxin, preferably a toxin from Bacillus species, more preferably from Bacillus thuringiensis.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a plant, which express at least one insecticidal toxin, preferably a toxin from Bacillus species, more preferably from Bacillus thuringiensis.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant is a plant, which express at least one insecticidal toxin, preferably a toxin from Bacillus species, more preferably from Bacillus thuringiensis.
- the cultivated plant has an arthropodicidal, preferably insecticidal, trait, it often occurs that the pest that should be combated becomes resistant to that trait.
- Resistance may be defined as ‘a heritable change in the sensitivity of a pest population that is reflected in the repeated failure of a product to achieve the expected level of control when used according to the label recommendation for that pest species’.
- IRAC Iron Resistance therefore means that the original activity of a pesticide against the target organisms (arthropods, insects) decreases or is even lost, due to genetic or metabolic adaptation of the target organism.
- “Resistant” to an insecticide is understood to mean resistant to at least one insecticide or insecticidal trait, i.e. the insect may be resistant to only one, but also to several insecticides or insecticidal traits.
- the resistance is against an insecticidal effect which is due to a genetic modification of a plant (modified or transgenic plant), which caused a resistance of the plant or crop to certain pests, especially insect pests, in susceptible insects.
- insecticidal proteins especially those mentioned herein, especially those known from the bacterial genus Bacillus , particularly from Bacillus thuringiensis , such as endotoxins, e. g. CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c; vegetative insecticidal proteins (VIP), e. g. VIP1, VIP2, VIP3 or VIP3A; insecticidal proteins of bacteria colonizing nematodes, for example Photorhabdus spp. or Xenorhabdus spp., and so on.
- endotoxins e. g. CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c
- VIP vegetative insecticidal proteins
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant has at least one insecticidal trait, and wherein the harmful insects are resistant to that at least one insecticidal trait of the plant.
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant has at least one insecticidal trait, and wherein the harmful insects are resistant to that at least one insecticidal trait of the plant.
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compound i) and ii), wherein the plant has at least one insecticidal trait, and wherein the harmful insects are resistant to that at least one insecticidal trait of the plant.
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant has at least one lepidopteran or coleopteran trait, and wherein the harmful insects are resistant to that lepidopteran or coleopteran insecticidal trait of the plant.
- the present invention also relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant has at least one lepidopteran or coleopteran trait, and wherein the harmful insects are resistant to that lepidopteran or coleopteran insecticidal trait of the plant.
- the present invention also relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant has at least one lepidopteran or coleopteran trait, and wherein the harmful insects are resistant to that lepidopteran or coleopteran insecticidal trait of the plant.
- Methods and uses of the invention as described herein may also involve a step of assessing whether insects are resistant to certain insecticides.
- This step will in general involve collecting a sample of insects from the area (e.g. crop, field, habitat) to be treated, before actually applying the carboxamide compound I, preferably compound i) of formula (I), and testing (for example using any suitable phenotypic, biochemical or molecular biological technique applicable) for resistance/sensitivity.
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant has at least one insecticidal trait, e.g. as listed in table A14 or B, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant has at least one insecticidal trait, e.g. as listed in table A14 or B, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant has at least one insecticidal trait, e.g. as listed in table A14 or B, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant is a plant, which shows increased resistance against fungal, viral and bacterial diseases, more preferably a plant, which expresses antipathogenic substances, such as antifungal proteins, or which has systemic acquired resistance properties.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a plant, which shows increased resistance against fungal, viral and bacterial diseases, more preferably a plant, which expresses antipathogenic substances, such as antifungal proteins, or which has systemic acquired resistance properties.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with a mixture comprising carboxamide compounds i) and ii) as component I and at least one compound II as component II, wherein the plant is a plant, which shows increased resistance against fungal, viral and bacterial diseases, more preferably a plant, which expresses antipathogenic substances, such as antifungal proteins, or which has systemic acquired resistance properties.
- the cultivated plants are plants, which are given in table A.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating plant propagation materials, preferably seeds with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating plant propagation materials, preferably seeds with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating plant propagation materials, preferably seeds with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- the cultivated plant is preferably selected from the group consisting of soybean, cotton and maize, wherein the plant has been made tolerant to the action of certain herbicides as described above. It is particularly preferred that the cultivated plant is selected from the group consisting of soybean, cotton and maize, wherein the plant has been made tolerant to the action of glyphosate herbicides.
- the cultivated plant is a plant, which has been made tolerant to the action of glyphosate herbicides.
- the plant may have been made tolerant to other herbicides and/or resistant to certain insects, and/or the plant may have been genetically modified otherwise, e.g. in terms of abiotic stress tolerance, altered growth/yield, disease resistance, modified product quality or pollination control system.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the mixture comprising the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the mixture comprising the carboxamide compound i) of formula
- component I as component I and at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant having the insecticidal trait corresponds to a row of table A14, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- Syngenta Glyphosate tolerance + MIR604 ⁇ Bt11 ⁇ (corn, maize) Agrisure ® Duracade TM Coleopteran resistance + TC1507 ⁇ 5222 Lepidopteran resistance + GA21 ⁇ Modified alpha amylase + MIR162 Mannose metabolism A14-26 Glufosinate tolerance + 59122 ⁇ GA21 Zea mays L.
- Syngenta Glyphosate tolerance + (corn, maize) Coleopteran resistance A14-27 Glufosinate tolerance + 59122 ⁇ Zea mays L.
- DuPont (Pioneer Hi- Glyphosate tolerance + MON810 ⁇ (corn, maize) Bred International Coleopteran resistance + NK603 Inc.) Lepidopteran resistance A14-30 Glufosinate tolerance + 59122 ⁇ Zea mays L. Monsanto Company Glyphosate tolerance + MON88017 (corn, maize) Coleopteran resistance A14-31 Glufosinate tolerance + 59122 ⁇ Zea mays L. Syngenta Glyphosate tolerance + TC1507 ⁇ (corn, maize) Coleopteran resistance + GA21 Lepidopteran resistance A14-32 Glufosinate tolerance + 98140 ⁇ 59122 Zea mays L.
- DuPont (Pioneer Hi- Coleopteran resistance + NK603 (corn, maize) Bred International Mannose metabolism Inc.) A14-50 Glyphosate tolerance + MON801 Zea mays L. Monsanto Company Lepidopteran resistance + (MON80100) (corn, maize) antibiotic resistance A14-51 Glyphosate tolerance + MON810 Zea mays L. available, Monsanto Lepidopteran resistance + (corn, maize) Company; Yield- antibiotic resistance Card TM, Maize- Gard TM A14-52 Glyphosate tolerance + MON87411 Zea mays L.
- DuPont Glyphosate tolerance + 59122 ⁇ (corn, maize) (Pioneer Hi-Bred Coleopteran resistance + MON810 ⁇ International Inc.); Lepidopteran resistance + MIR604 ⁇ Optimum TM Intrasect Mannose metabolism NK603 Xtrenne A14-70 Glufosinate tolerance + TC1507 ⁇ Zea mays L.
- DuPont (Pioneer Hi- Glyphosate tolerance + MON810 ⁇ (corn, maize) Bred International Coleopteran resistance + MIR604 ⁇ Inc.) Lepidopteran resistance + NK603 Antibiotic resistance + Mannose metabolism A14-71 Glufosinate tolerance + TC1507 ⁇ Zea mays L.
- DuPont Glyphosate tolerance + 59122 ⁇ (corn, maize) (Pioneer Hi-Bred Coleopteran resistance + MON810 ⁇ International Inc.); Lepidopteran resistance NK603 Optimum TM Intrasect XTRA A14-72 Glufosinate tolerance + TC1507 ⁇ Zea mays L.
- DuPont Glyphosate tolerance + MIR604 ⁇ (corn, maize) (Pioneer Hi-Bred Coleopteran resistance + NK603 International Inc.); Lepidopteran resistance + Optimum TM TRIsect Mannose metabolism A14-76 Glufosinate tolerance + TC1507 ⁇ Zea mays L.
- DuPont (Pioneer Hi- Glyphosate tolerance + MON810 ⁇ (corn, maize) Bred International Lepidopteran resistance + MIR162 ⁇ Inc.) Mannose metabolism NK603 A14-77 Glufosinate tolerance + TC1507 ⁇ Zea mays L.
- DuPont Glyphosate tolerance + MON810 ⁇ (corn, maize) (Pioneer Hi-Bred Lepidopteran resistance NK603 International Inc.); Optimum TM Intrasect A14-78 Glufosinate tolerance + TC1507 ⁇ Zea mays L. Monsanto Company Glyphosate tolerance + MON88017 (corn, maize) and Dow AgroSciences Coleopteran resistance + LLC Lepidopteran resistance A14-79 Glyphosate tolerance VCO- ⁇ 1981-5 Zea mays L. Genective S. A. (corn, maize)
- the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the mixture comprising the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the mixture comprising the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant having the insecticidal trait corresponds to a row of table A14, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the mixture comprising 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the mixture comprising 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant having the insecticidal trait corresponds to a row of table A14, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- Insect resistance in particular lepidopteran resistance is of growing importance in GMO crops. Furthermore, it has been found that insects often become resistant to the crops, which have been modified in terms of insect resistance. It has been found that the carboxamide compound I, preferably compound i) of formula (I) are particularly suitable for combating insects, which have become resistant to the crops, which have been modified in terms of insect resistance. In particular, the carboxamide compound I, preferably compound i) of formula (I) may advantageously be applied in soybeans, which have been made resistant to insects.
- the cultivated plant is soybean, which has been made resistant to lepidoperan insects.
- the soybean may have been made tolerant to certain herbicides and/or resistant to other insects, and/or the soybean may have been genetically modified otherwise, e.g. in terms of abiotic stress tolerance, altered growth/yield, disease resistance, modified product quality or pollination control system.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the carboxamide compound i) of formula (I), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the carboxamide compound I, preferably compound ii) of formula (Ia), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with a mixture comprising the carboxamide compounds i) and ii), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- Lepidopteran resistance of soybeans is typically achieved by introducing a gene selected from the group consisting of: cry1Ac (gene source: Bacillus thuringiensis subsp. Kurstaki strain H D73), cry1F (gene source: Bacillus thuringiensis var. aizawai ), cry1A.105 (gene source: Bacillus thuringiensis subsp. Kumamotoensis ), cry2Ab2 (gene source: Bacillus thuringiensis subsp. Kumamotoensis ), and combinations thereof.
- cry1Ac gene source: Bacillus thuringiensis subsp. Kurstaki strain H D73
- cry1F gene source: Bacillus thuringiensis var. aizawai
- cry1A.105 gene source: Bacillus thuringiensis subsp. Kumamotoensis
- cry2Ab2 gene source: Bacillus thuringiensis subsp. Kumamoto
- the soybeans are additionally modified in terms of glyphosate tolerance by introducing the gene cp4 epsps (aroA:CP4).
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the carboxamide compound i) of formula (I), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the carboxamide compound ii) of formula (Ia), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with a mixture comprising the carboxamide compounds i) and ii), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- the present invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound i) of formula (I), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is
- the invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound ii) of formula (Ia), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is
- the invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of a mixture comprising the carboxamide compounds i) and ii) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is
- present invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound i) of formula (I), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is modified by at least one gene according to one row of table D.
- the invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound ii) of formula (Ia), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is modified by at least one gene according to one row of table D.
- the invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of a mixture comprising the carboxamide compounds i) and ii) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is modified by at least one gene according to one row of table D.
- Further preferred embodiments of the invention are those methods of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or at their locus of growth with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- Further embodiments of the invention are those methods of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or at their locus of growth with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- Further embodiments of the invention are those methods of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or at their locus of growth with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is teflubenzuron and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is teflubenzuron and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is teflubenzuron and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is chlorfenapyr and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is chlorfenapyr and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is chlorfenapyr and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoy
- the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl
- the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)
- the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is thiamethoxam and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is thiamethoxam and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of 1) a mixture of the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is thiamethoxam and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is fipronil and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is fipronil and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of 1) a mixture of the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is fipronil and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-
- the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl
- the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole
- the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture 1) a mixture of the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]
- the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene) ⁇ carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole
- inventions of this invention are methods for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound ii) of formula (Ia), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth.
- inventions of this invention are e.g. methods for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of a mixture comprising the carboxamide compounds i) and ii) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth.
- the cultivated plant is a plant with at least one property selected from: herbicide tolerance, insect resistance, fungal resistance or viral resistance or bacterial resistance, stress tolerance, maturation alteration, content modification of chemicals present in the cultivated plant, modified nutrient uptake, antibiotic resistance and male sterility compared to the corresponding control plant respectively.
- a plant with at least one trait of the category herbicide tolerance a plant with at least one trait of the category insect resistance, or a plant with at least two traits, wherein at least one trait is of the category of herbicide tolerance and at least one trait is of the category of insect resistance.
- the herbicide resistance is preferably selected from the group consisting of glyphosate tolerance, glufosinate tolerance, and imidazolinone tolerance, and is particularly preferably glyphosate tolerance.
- the insect resistance is preferably selected from the group consisting of lepidoperan resistance and coleopteran resistance, and is particularly preferably lepidopteran resistance.
- the cultivated plant has at least one trait of the category insect resistance, preferably at least two genes confer insect resistance to the cultivated plant.
- cultivated plants wherein the cultivated plant is selected from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize), Glycine max L. (soybean), Triticum aestivum (wheat), and Oryza sativa L. (rice), preferably from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize) and Glycine max L. (soybean).
- the cultivated plant is selected from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize) and Glycine max L. (soybean).
- cultivated plants preferably are selected:
- (rice) and comprises at least one gene selected from the group consisting of cry34Ab1, cry35 Ab1, cry3A, cry3Bb1, dvsnf7, mcry3A, cry1A, cry1A.105, cry1Ab, cry1Ab-Ac, cry1Ac, cry1C, cry1F, cry1Fa2, cry2Ab2, cry2Ae, cry9c, mocry1F, pinII, vip3A(a), vip3Aa20.
- the modification is selected from the events provided in table A14.
- a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant comprising the application of the carboxamide compound i) of formula (I) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is a soybean variety with glyphosate tolerance and lepidopteran resistance, wherein the glyphosate tolerance is preferably through the expression of the cp4epsps gene, and more preferably based on the transgenic event MON89788, and wherein the lepidopteran resistance is preferably through expression of the Cry1AC encoding gene from B. thuringiensis , preferably against velvetbean caterpillar ( Anticarsia gemmatalis ) and soybean looper ( Pseudoplusia includens ), and more preferably based on the transgenic event MON87701.
- Another method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant comprising the application of the carboxamide compound ii) of formula (Ia) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is a soybean variety with glyphosate tolerance and lepidopteran resistance, wherein the glyphosate tolerance is preferably through the expression of the cp4epsps gene, and more preferably based on the transgenic event MON89788, and wherein the lepidopteran resistance is preferably through expression of the Cry1AC encoding gene from B. thuringiensis , preferably against velvetbean caterpillar ( Anticarsia gemmatalis ) and soybean looper ( Pseudoplusia includens), and more preferably based on the transgenic event MON87701.
- Still another method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant comprising the application of a mixture comprising the carboxamide compounds i) and ii) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is a soybean variety with glyphosate tolerance and lepidopteran resistance, wherein the glyphosate tolerance is preferably through the expression of the cp4epsps gene, and more preferably based on the transgenic event MON89788, and wherein the lepidopteran resistance is preferably through expression of the Cry1AC encoding gene from B. thuringiensis , preferably against velvetbean caterpillar ( Anticarsia gemmatalis ) and soybean looper ( Pseudoplusia includens ), and more preferably based on the transgenic event MON87701.
- the cultivated plant is “Intacta RR2 PRO” soybean (Monsanto), which claims to offer tolerance to glyphosate herbicide and protection against major soybean pests (velvetbean caterpilar, soybean looper, soybean budborer, bean shoot borer, bollworm, corn stalk borer, Helicoverpa , e.g. Helicoverpa armigera ), along with increased yield potential.
- Major soybean pests velvetbean caterpilar, soybean looper, soybean budborer, bean shoot borer, bollworm, corn stalk borer, Helicoverpa , e.g. Helicoverpa armigera , along with increased yield potential.
- the carboxamide compound i) of formula (I) is applied to the plant propagation material of the cultivated plant.
- the plant propagation material are the seeds.
- the carboxamide compound ii) of formula (Ia) is applied to the plant propagation material of the cultivated plant.
- the plant propagation material are the seeds.
- the mixture comprising the carboxamide compounds i) and ii) is applied to the plant propagation material of the cultivated plant.
- the plant propagation material are the seeds.
- the carboxamide compound i) of formula (I) is applied in a mixture of (1) the carboxamide compound i) of formula (I), and (2) at least one further pesticidal compound II as component II, wherein the pesiticdal compound II is an insecticide or a fungicide.
- the carboxamide compound ii) of formula (Ia) is applied in a mixture of (1) the carboxamide compound ii) of formula (Ia), and (2) at least one further pesticidal compound II as component II, wherein the pesiticdal compound II is an insecticide or a fungicide.
- the carboxamide compound i) of formula (I) is applied in a mixture of (1) a mixture comprising the carboxamide compounds i) and ii) and (2) at least one further pesticidal compound II as component II, wherein the pesiticdal compound II is an insecticide or a fungicide.
- the mixture of the invention or the carboxamide compound i) of formula (I) may be provided in the form of an agrochemical composition comprising the carboxamide compound i) of formula (I) together with one or more other pesticidal active ingredient(s) and an auxiliary.
- An agrochemical composition comprises a pesticidally effective amount the carboxamide compound i) of formula (I), a pesticidally effective amount of the carboxamide compound ii) of formula (Ia) or a pesticidally effective amount of the mixture comprising the carboxamide compounds i) and ii).
- the mixture of the invention or the carboxamide compound ii) of formula (Ia) may be provided in the form of an agrochemical composition comprising the carboxamide compound ii) of formula (Ia) together with one or more other pesticidal active ingredient(s) and an auxiliary.
- Still other embodiments relate (1) to the mixture of the invention comprising the mixture comprising the carboxamide compounds i) and ii) as well as uses and methods comprising the application of said mixture and (2) to uses and methods comprising the application of the mixture comprising the carboxamide compounds i) and ii) according to the invention.
- the mixture of the invention or the mixture comprising the carboxamide compounds i) and ii) may be provided in the form of an agrochemical composition comprising the mixture comprising the carboxamide compounds i) and ii) together with one or more other pesticidal active ingredient(s) and an auxiliary.
- An agrochemical composition comprises a pesticidally effective amount the carboxamide compound i) of formula (I), a pesticidally effective amount of the carboxamide compound ii) of formula (Ia) or a pesticidally effective amount of the mixture comprising the carboxamide compounds i) and ii).
- compositions comprising the carboxamide compound i) of formula (I), compound ii) of formula (la) or a mixture comprising the carboxamide compounds i) and ii) of the present invention can be converted into customary types of agrochemical compositions, e. g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof.
- agrochemical compositions e.g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof.
- composition types are suspensions (e.g. SC, OD, FS), emulsifiable concentrates (e.g. EC), emulsions (e.g. EW, EO, ES, ME), capsules (e.g.
- compositions types are defined in the “Catalogue of pesticide formulation types and international coding system”, Technical Mono-graph No. 2, 6th Ed. May 2008, CropLife International.
- compositions are prepared in a known manner, such as described by Mollet and Grubemann, Formulation technology, Wiley VCH, Weinheim, 2001; or Knowles, New developments in crop protection product formulation, Agrow Reports DS243, T&F Informa, London, 2005.
- auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfactants, dispersants, emulsifiers, wetters, adjuvants, solubilizers, penetration enhancers, protective colloids, adhesion agents, thickeners, humectants, repellents, attractants, feeding stimulants, compatibilizers, bactericides, anti-freezing agents, anti-foaming agents, colorants, tackifiers and binders.
- Suitable solvents and liquid carriers are water and organic solvents, such as mineral oil fractions of medium to high boiling point, e.g. kerosene, diesel oil; oils of vegetable or animal origin; aliphatic, cyclic and aromatic hydrocarbons, e. g. toluene, paraffin, tetrahydronaphthalene, alkylated naphthalenes; alcohols, e.g. ethanol, propanol, butanol, benzylalcohol, cyclo ⁇ hexanol; glycols; DMSO; ketones, e.g. cyclohexanone; esters, e.g.
- mineral oil fractions of medium to high boiling point e.g. kerosene, diesel oil
- oils of vegetable or animal origin oils of vegetable or animal origin
- aliphatic, cyclic and aromatic hydrocarbons e. g. toluene, paraffin, tetrahydronaphthalene, alkyl
- lactates carbonates, fatty acid esters, gamma-butyrolactone; fatty acids; phosphonates; amines; amides, e.g. N-methylpyrrolidone, fatty acid dimethylamides; and mixtures thereof.
- Suitable solid carriers or fillers are mineral earths, e.g. silicates, silica gels, talc, kaolins, limestone, lime, chalk, clays, dolomite, diatomaceous earth, bentonite, calcium sulfate, magnesium sulfate, magnesium oxide; polysaccharide powders, e.g. cellulose, starch; fertilizers, e.g. ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas; products of vegetable origin, e.g. cereal meal, tree bark meal, wood meal, nutshell meal, and mixtures thereof.
- mineral earths e.g. silicates, silica gels, talc, kaolins, limestone, lime, chalk, clays, dolomite, diatomaceous earth, bentonite, calcium sulfate, magnesium sulfate, magnesium oxide
- polysaccharide powders e.g. cellulose, starch
- Suitable surfactants are surface-active compounds, such as anionic, cationic, nonionic and amphoteric surfactants, block polymers, polyelectrolytes, and mixtures thereof. Such surfactants can be used as emulsifier, dispersant, solubilizer, wetter, penetration enhancer, protective colloid, or adjuvant. Examples of surfactants are listed in McCutcheon's, Vol. 1: Emulsifiers & Detergents, McCutcheon's Directories, Glen Rock, USA, 2008 (International Ed. or North American Ed.).
- Suitable anionic surfactants are alkali, alkaline earth or ammonium salts of sulfonates, sulfates, phosphates, carboxylates, and mixtures thereof.
- sulfonates are alkylarylsulfonates, diphenylsulfonates, alpha-olefin sulfonates, lignine sulfonates, sulfonates of fatty acids and oils, sulfonates of ethoxylated alkylphenols, sulfonates of alkoxylated arylphenols, sulfonates of condensed naphthalenes, sulfonates of dodecyl- and tridecylbenzenes, sulfonates of naphthalenes and alkyl ⁇ naphthalenes, sulfosuccinates or sulfosuccinamates.
- Examples of sulfates are sulfates of fatty acids and oils, of ethoxylated alkylphenols, of alcohols, of ethoxylated alcohols, or of fatty acid esters.
- Examples of phosphates are phosphate esters.
- Examples of carboxylates are alkyl carboxylates, and carboxylated alcohol or alkylphenol ethoxylates.
- Suitable nonionic surfactants are alkoxylates, N-substituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants, and mixtures thereof.
- alkoxylates are compounds such as alcohols, alkylphenols, amines, amides, arylphenols, fatty acids or fatty acid esters which have been alkoxylated with 1 to 50 equivalents.
- Ethylene oxide and/or propylene oxide may be employed for the alkoxylation, preferably ethylene oxide.
- N-substituted fatty acid amides are fatty acid glucamides or fatty acid alkanolamides.
- esters are fatty acid esters, glycerol esters or monoglycerides.
- sugar-based surfactants are sorbitans, ethoxylated sorbitans, sucrose and glucose esters or alkylpolyglucosides.
- polymeric surfactants are homo- or copolymers of vinylpyrrolidone, vinylalcohols, or vinylacetate.
- Suitable cationic surfactants are quaternary surfactants, for example quaternary ammonium compounds with one or two hydrophobic groups, or salts of long-chain primary amines.
- Suitable amphoteric surfactants are alkylbetains and imidazolines.
- Suitable block polymers are block polymers of the A-B or A-B-A type comprising blocks of polyethylene oxide and polypropylene oxide, or of the A-B—C type comprising alkanol, polyethylene oxide and polypropylene oxide.
- Suitable polyelectrolytes are polyacids or polybases. Examples of polyacids are alkali salts of polyacrylic acid or polyacid comb polymers. Examples of polybases are polyvinylamines or polyethyleneamines.
- Suitable adjuvants are compounds, which have a neglectable or even no pesticidal activity themselves, and which improve the biological performance of the active ingredients(s) on the target.
- examples are surfactants, mineral or vegetable oils, and other auxilaries. Further examples are listed by Knowles, Adjuvants and additives, Agrow Reports DS256, T&F Informa UK, 2006, chapter 5.
- Suitable thickeners are polysaccharides (e.g. xanthan gum, carboxymethylcellulose), anorganic clays (organically modified or unmodified), polycarboxylates, and silicates.
- Suitable bactericides are bronopol and isothiazolinone derivatives such as alkylisothiazolinones and benzisothiazolinones.
- Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.
- Suitable anti-foaming agents are silicones, long chain alcohols, and salts of fatty acids.
- Suitable colorants are pigments of low water solubility and water-soluble dyes.
- examples are inorganic colorants (e.g. iron oxide, titan oxide, iron hexacyanoferrate) and organic colorants (e.g. alizarin-, azo- and phthalocyanine colorants).
- Suitable tackifiers or binders are polyvinylpyrrolidons, polyvinylacetates, polyvinyl alcohols, polyacrylates, biological or synthetic waxes, and cellulose ethers.
- composition types and their preparation are:
- 10-60 wt % of the pesticidal active compound(s), and 5-15 wt % wetting agent e.g. alcohol alkoxylates
- a water-soluble solvent e.g. alcohols
- dispersant e. g. polyvinylpyrrolidone
- organic solvent e.g. cyclohexanone
- emulsifiers e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate
- water-insoluble organic solvent e.g. aromatic hydrocarbon
- Emulsions (EW, EO, ES)
- emulsifiers e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate
- 20-40 wt % water-insoluble organic solvent e.g. aromatic hydrocarbon
- 20-60 wt % of the pesticidal active compound(s) are comminuted with addition of 2-10 wt % dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate), 0.1-2 wt % thickener (e.g. xanthan gum) and up to 100 wt % water to give a fine active substance suspension. Dilution with water gives a stable suspension of the active substance.
- dispersants and wetting agents e.g. sodium lignosulfonate and alcohol ethoxylate
- 0.1-2 wt % thickener e.g. xanthan gum
- 50-80 wt % of the pesticidal active compound(s) are ground finely with addition of up to 100 wt % dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate) and prepared as water-dispersible or water-soluble granules by means of technical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substance.
- dispersants and wetting agents e.g. sodium lignosulfonate and alcohol ethoxylate
- 50-80 wt % of the pesticidal active compound(s) are ground in a rotor-stator mill with ad-dition of 1-5 wt % dispersants (e.g. sodium lignosulfonate), 1-3 wt % wetting agents (e.g. alcohol ethoxylate) and up to 100 wt % solid carrier, e.g. silica gel. Dilution with water gives a stable dispersion or solution of the active substance.
- dispersants e.g. sodium lignosulfonate
- wetting agents e.g. alcohol ethoxylate
- solid carrier e.g. silica gel
- the pesticidal active compound(s) are comminuted with addition of 3-10 wt % dispersants (e.g. sodium lignosulfonate), 1-5 wt % thickener (e.g. carboxymethylcellulose) and up to 100 wt % water to give a fine suspension of the active substance. Dilution with water gives a stable suspension of the active substance.
- dispersants e.g. sodium lignosulfonate
- 1-5 wt % thickener e.g. carboxymethylcellulose
- 5-20 wt % of the pesticidal active compound(s) are added to 5-30 wt % organic solvent blend (e.g. fatty acid dimethylamide and cyclohexanone), 10-25 wt % surfactant blend (e.g. alkohol ethoxylate and arylphenol ethoxylate), and water up to 100%. This mixture is stirred for 1 h to produce spontaneously a thermodynamically stable microemulsion.
- organic solvent blend e.g. fatty acid dimethylamide and cyclohexanone
- surfactant blend e.g. alkohol ethoxylate and arylphenol ethoxylate
- An oil phase comprising 5-50 wt % of the pesticidal active compound(s), 0-40 wt % water insoluble organic solvent (e.g. aromatic hydrocarbon), 2-15 wt % acrylic monomers (e.g. methylmethacrylate, methacrylic acid and a di- or triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization initiated by a radi-cal initiator results in the formation of poly(meth)acrylate microcapsules.
- an oil phase comprising 5-50 wt % of the pesticidal active compound(s), 0-40 wt % water insoluble organic solvent (e.g.
- an isocyanate monomer e.g. diphenylme-thene-4,4′-diisocyanatae
- a protective colloid e.g. polyvinyl alcohol
- the addition of a polyamine results in the for-mation of a polyurea microcapsule.
- the monomers amount to 1-10 wt %.
- the wt % relate to the total CS composition.
- Dustable powders (DP, DS)
- 1-10 wt % of pesticidal active compound(s), are ground finely and mixed intimately with up to 100 wt % solid carrier, e.g. finely divided kaolin.
- 0.5-30 wt % of v is ground finely and associated with up to 100 wt % solid carrier (e.g. silicate).
- Granulation is achieved by extrusion, spray-drying or the fluidized bed.
- 1-50 wt % of pesticidal active compound(s), are dissolved in up to 100 wt % organic solvent, e.g. aromatic hydrocarbon.
- compositions types i) to xi) may optionally comprise further auxiliaries, such as 0.1-1 wt % bactericides, 5-15 wt % anti-freezing agents, 0.1-1 wt % anti-foaming agents, and 0.1-1 wt % colorants.
- auxiliaries such as 0.1-1 wt % bactericides, 5-15 wt % anti-freezing agents, 0.1-1 wt % anti-foaming agents, and 0.1-1 wt % colorants.
- the agrochemical compositions generally comprise between 0.01 and 95%, preferably between 0.1 and 90%, and most preferably between 0.5 and 75%, by weight of active substance.
- the active substances are employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).
- oils, wetters, adjuvants, fertilizer, or micronutrients, and other pesticides may be added to the active substances or the compositions comprising them as premix or, if appropriate not until immediately prior to use (tank mix).
- pesticides e.g. herbicides, insecticides, fungicides, growth regulators, safeners
- These agents can be admixed with the compositions according to the invention in a weight ratio of 1:100 to 100:1, preferably 1:10 to 10:1.
- the user applies the composition according to the invention usually from a predosage de-vice, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system.
- the agrochemical composition is made up with water, buffer, and/or further auxiliaries to the desired application concentration and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained.
- 20 to 2000 liters, preferably 50 to 400 liters, of the ready-to-use spray liquor are applied per hectare of agricultural useful area.
- composition according to the invention such as parts of a kit or parts of a binary or ternary mixture may be mixed by the user himself in a spray tank and further auxiliaries may be added, if appropriate.
- either individual components of the composition according to the invention or partially premixed components, e.g. components comprising pesticidal active compound(s), may be mixed by the user in a spray tank and further auxiliaries and additives may be added, if appropriate.
- either individual components of the composition according to the invention or partially premixed components, e. g. components comprising pesticidal active compound(s), can be applied jointly (e.g. after tank mix) or consecutively.
- Conventional seed treatment formulations include for example flowable concentrates FS, solutions LS, suspoemulsions (SE), powders for dry treatment DS, water dispersible powders for slurry treatment WS, water-soluble powders SS and emulsion ES and EC and gel formulation GF. These formulations can be applied to the seed diluted or undiluted. Application to the seeds is carried out before sowing, either directly on the seeds or after having pregerminated the latter. Preferably, the formulations are applied such that germination is not included.
- the active substance concentrations in ready-to-use formulations are preferably from 0.01 to 60% by weight, more preferably from 0.1 to 40% by weight.
- a FS formulation is used for seed treatment.
- a FS formulation may comprise 1-800 g/l of active ingredient, 1-200 g/l Surfactant, 0 to 200 g/l antifreezing agent, 0 to 400 g/l of binder, 0 to 200 g/l of a pigment and up to 1 liter of a solvent, preferably water.
- Especially preferred FS formulations of the compound I, preferably compound i) of formula (I), for seed treatment usually comprise from 0.1 to 80% by weight (1 to 800 g/l) of the active ingredient, from 0.1 to 20% by weight (1 to 200 g/l) of at least one surfactant, e.g. 0.05 to 5% by weight of a wetter and from 0.5 to 15% by weight of a dispersing agent, up to 20% by weight, e.g. from 5 to 20% of an anti-freeze agent, from 0 to 15% by weight, e.g. 1 to 15% by weight of a pigment and/or a dye, from 0 to 40% by weight, e.g.
- a binder optionally up to 5% by weight, e.g. from 0.1 to 5% by weight of a thickener, optionally from 0.1 to 2% of an anti-foam agent, and optionally a preservative such as a biocide, antioxidant or the like, e.g. in an amount from 0.01 to 1% by weight and a filler/vehicle up to 100% by weight.
- the application rates of the carboxamide compound i) of formula (I), of the carboxamide compound ii) of formula (Ia) or of a mixture comprising the carboxamide compounds i) and ii), are generally from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, more preferably from 1 g to 1000 g per 100 kg of seed and in particular from 1 g to 200 g per 100 kg of seed, e.g. from 1 g to 100 g or from 5 g to 100 g per 100 kg of seed.
- the invention therefore also relates to seed comprising one of the carboxamide compound i) of formula (I), the carboxamide compound ii) of formula (Ia) or the mixture comprising the carboxamide compounds i) and ii).
- the amount of the carboxamide compound i) of formula (I), the carboxamide compound ii) of formula (Ia) or the mixture comprising the carboxamide compounds i) and ii) will in general vary from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed. For specific crops such as lettuce the rate can be higher.
- the present invention may be illustrated by the following example.
- the interaction between the carboxamide compound of the present invention (or compositions comprising it) and the cultivated plant may be evaluated in different test systems. As well for the comparison to non-cultivated plants or to mixtures (comprising the carboxamide compound) synergism may be shown.
- Synergism can be described as an interaction where the combined effect of two or more compounds is greater than the sum of the individual effects of each of the compounds.
- the presence of a synergistic effect in terms of percent control, between two mixing partners (X and Y) can be calculated using the Colby equation (Colby, S. R., 1967, Calculating Synergistic and Antagonistic Responses in Herbicide Combinations, Weeds, 15, 20-22):
- B1 Test on cultivated soybeans Trial is carried out under greenhouse conditions on soybean (genetically modified plant variety, e.g. roundup, growth stage 109). 12 treatments are compared in a complete randomized blocks (4 replications) with plot size of 1 m ⁇ 3 meters. Only selected plants are considered for artificial infestation and evaluations. Due to glyphosate timing for application on such cultivated soybeans, all treatments are applied in older plants (GS 109) otherwise a significant phytotoxicity is expected. Application is done, using 400 l/ha. All treatments are applied using a CO2 backpack (nozzle type TXVK-10). Temperature at the time of applications is around 25 to 30° C. and air humidity is between 30 and 100%. Soil condition is e.g.
- R4 (when ⁇ 75% of surface is dried up) and the moisture is moist (normal).
- Roundup Original® (Glyfosate-sal isopropilamina @360 g/L) is used in the rate of 867 g a.i./ha. Artificial infestation is done one day after the application.
- the species used is Anticarsia gemmatalis (Hübner) [ Thermesia elegantula (Herrich-Schaffer, 1869)], Noctuidae. 5 plants/plot are infested with 3 larvae (stage L2) using an entomological metallic tweezers, totaling 15 larvae per repetition. Larvae used in this trial are e.g.
Abstract
Description
- In a first aspect, the present invention relates to a method for controlling pests on and/or increasing the plant health of a cultivated plant with at least one modification (hereinafter abbreviated as “cultivated plant”) as compared to a respective non-modified control plant.
- The method comprises the application of a pesticidal carboxamide compound (alone or in the form of a mixture comprising such pesticidal carboxamide compound) to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth.
- In a further aspect, the present invention relates to a method for controlling pests and/or increasing the plant health of a cultivated plant with at least one modification as compared to the respective non-modified control plant, comprising the application of an pesticidal carboxamide compound (again, alone or in the form a mixture comprising such pesticidal carboxamide compound) to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth, wherein said cultivated plant is selected from a group of certain plants with specific modifications as defined further below.
- The methods of the invention relating to cultivated plants are particularly suitable for efficiently controlling arthropodal pests such as arachnids, myriapedes and insects as well as nematodes on cultivated plants. Preferably, the term pests embrace animal pests (such as insects, acarids or nematodes). Relevant animal pests of different genera and species are provided further below.
- In another aspect, the present invention relates to the use of a pesticidal carboxamide compound alone or in the form of a pesticidal mixture comprising such pesticidal carboxamide compound for protecting a cultivated plant, modified plant propagation material, or its locus of growth, against the attack or infestation by pests.
- In still another aspect, the present invention relates to the use of a pesticidal carboxamide compound in pesticidally effective amounts for protecting cultivated plants from row crops such as cotton, corn or soybean plants, the plant propagation material thereof or their locus of growth.
- In still another aspect, the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of an pesticidal carboxamide compound to a row crop plant (such as corn, cotton or soybean plant), the plant propagation material thereof or at its locus of growth, also on the pests or their food supply, habitat or breeding grounds.
- In still another aspect, the present invention relates to the method of application or the use of a pesticidal carboxamide compound in pesticidally effective amounts for protecting cultivated plants from row crops such as cotton, corn or soybean plants, the plant propagation material thereof or their locus of growth from the infestions by pests, wherein the pests are selected from the orders of Lepidoptera, Coleoptera or Thysanoptera, and combinations thereof.
- In yet another aspect, the present invention relates to the use of an pesticidal carboxamide compound in pesticidally effective amounts for protecting a soybean plant, the plant propagation material thereof, or its locus of growth, against the attack or infestation by pests selected from the group consisting of Anticarsia gemmatalis, Chlysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera eridania, Spodoptera frugiperda, and combinations thereof.
- In yet another aspect, the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of an pesticidal carboxamide compound to a soybean plant, the plant propagation material thereof or its locus of growth; the pests or their food supply, habitat or breeding grounds, wherein the pests are selected from the group consisting of Anticarsia gemmatalis, Chrysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera eridania, Spodoptera frugiperda, and combinations thereof.
- Pests, in particular insects from the order of Lepidoptera, destroy growing and harvested crops and attack wooden dwelling and commercial structures, thereby causing large economic loss to the food supply and to property. A particular important threat in connection with Lepidoptera, particular leaf eating caterpillars, is defoliation of the plants, which typically results in a decrease of the yield. In connection with soybean, it has e.g. been found that, when the pods begin to form and fill out, any foliage loss greater than 20% will decrease the yield (G. Andrews et al., Insect control guides for cotton, soybeans, corn, grain sorghum, wheat, sweet potatoes and pastures, Mississippi State University Extension Service, Publication 2471, 64 pp. (2009)).
- It is known in the art that row crops, such as wheat, maize, rice, soybean, and cotton, in particular soybean, are particularly vulnerable in terms of the attack or infestation by Lepidoptera selected from the group consisting of Anticarsia (=Thermesia) spp., Chrysodeixis (=Pseudoplusia) spp., Helicoverpa spp., and Spodoptera (=Lamphygma) spp. The most important species include Anticarsia gemmatalis, Chlysodeixis includens (=Pseudoplusia includens), Helicoverpa armigera (=Heliothis armigera), Spodoptera frugiperda, Spodoptera eridania, and Spodoptera cosmioides.
- The relevance of Anticarsia gemmatalis, Pseudoplusia includens, Spodoptera frugiperda, Spodoptera eridania, and Spodoptera cosmioides for defoliation of soybean genotypes is analyzed by R. C. O. de Freitas Bueno et al. in Pest Manag. Sci. 2011; 67: 170-174. It is said therein that Anticarsia gemmatalis was originally the most important defoliator insect occurring on soybean crops, but that nowadays Pseudoplusia includens, Spodoptera frugiperda, Spodoptera eridania, and Spodoptera cosmioides are also considered to be key pests by Brazilian soybean growers.
- In recent years, there were also numerous reports in the media regarding the growing threat of Helicoverpa armigera to Brazilian cotton, corn and soybean crops.
- According to O. Bernardi et al. (Crop Protection 2014; 58: 33-40), it has been observed that Spodoptera frugiperda, Spodoptera eridania, and Spodoptera cosmioides have caused significant damage on soybean in Brazil. It has been found that these Spodoptera species also have a low susceptibility to genetically modified soybeans expressing cry1Ac protein. It is concluded that the cry1Ac expressing soybeans show poor control of these Spodoptera species, and that, consequently, other control tactics must be used in combination with MON 87701 x MON 89788 soybean in the field for the efficient management of these Spodoptera species.
- Similar problems are to be expected in connection with genetically modified soybeans expressing cry1F or a combination of cry1F and cry1Ac (e.g. DAS 81419) for the reason that cry1F in many species interacts with the known receptor for cry1Ac indicating a similar insecticidal activity, which may contribute to cross-resistance to both toxins (Center for Environmental Risk Assessment, ILSI Research Foundation, Washington D.C., USA, 2013: “A Review of the Environmental Safety of the Cry1F Protein”).
- Accordingly, there is an acute need for pesticides and pesticidal mixtures for controlling the above mentioned pests on the above mentioned row crops, including plants, which have been modified by mutagenesis or genetic engineering, and plants, which have not been modified by mutagenesis or genetic engineering. In particular, there is a need for pesticides and pesticidal mixtures for controlling the above mentioned pests on row crops, which have been modified by mutagenesis or genetic engineering, in particular on soybean plants, which have been modified by mutagenesis or genetic engineering.
- It is therefore an object of the present invention to provide a pesticidal mixture, which is suitable for controlling pests, in particular from the orders of Lepidoptera, Coleoptera or Thysanoptera, preferably Lepidoptera and more preferably any one of the above mentioned Lepidoptera genera and species, or combinations thereof, which are of particular relevance in connection with wheat, maize, rice, soybean, and cotton plants. And in particular in connection with soybean plants, especially in connection with soybean plants, which have been modified by mutagenesis or genetic engineering, e.g. insect resistant soybeans expressing cry1Ac, cry1F, or a combination thereof.
- In this connection, it is also an object of the invention to provide a pesticidal compound or a pesticidal mixture, which overcome insect resistance problems in connection with the herein mentioned pests. As used herein, the term “insect resistance” refers to insect resistance against other pesticides and pesticidal mixtures or insect resistance against an insecticidal trait of a plant.
- Furthermore, it is an object of the invention to provide a pesticidal mixture, which can be applied in lower dosage rates compared to other pesticides and pesticidal mixtures in order to avoid unfavorable environmental or toxicological effects.
- With regard to the pests Anticarsia gemmatalis, Chlysodeixis includens (=Pseudoplusia includens), Helicoverpa armigera (=Heliothis armigera), Spodoptera cosmioides, Spodoptera eridania, and Spodoptera frugiperda, which are typically present on soybeans, it is another object of the present invention to provide pesticides, which are suitable for selective pest control, if infestation with one or more of these pests occurs.
- The above objects may be achieved by a pesticidal active carboxamide compound, and the uses and methods comprising the application of said compound as defined hereinafter.
- It has surprisingly been found that the pesticidal mixture according to the invention is suitable for controlling the above mentioned pests, in particular Anticarsia (=Thermesia) spp., Chrysodeixis (=Pseudoplusia) spp., Helicoverpa spp., and Spodoptera (=Lamphygma) spp., especially Anticarsia gemmatalis, Chlysodeixis includens (=Pseudoplusia includens), Helicoverpa armigera (=Heliothis armigera), Spodoptera frugiperda, Spodoptera eridania, and Spodoptera cosmioides. Accordingly, plants selected from wheat, maize, rice, soybean, and cotton plants, in particular soybean plants may effectively be protected against defoliation by these pests, and a decrease of the yields can thus be prevented. In this connection, it is an important advantage of the method according to the present invention that the method is also suitable for controlling the above mentioned pests, if they have become resistant against conventional pesticides or pesticidal mixtures, or against the insecticidal trait of a plant.
- Furthermore, it has been found that the development of a resistance against the insecticidal trait of a plant can be prevented, if the plants are treated with the pesticidal carboxamide compound of the invention. Moreover, the method according to the invention is suitable for controlling pests, against which the insecticidal trait of a plant is not effective, so that a complementary insecticidal activity can advantageously be used.
- It is another advantage of the pesticidal method according to the present invention that the carboxamide compound and its mixtures can be applied in lower dosage rates compared to other pesticides and pesticidal mixtures.
- Furthermore, there are special interests in connection with cultivated plants with at least one modification.
- It has been observed that cultivated plants with at least one modification, for example a modification providing herbicide tolerance, are more susceptible to attack or infestation by pests than plants, which have not been modified.
- Furthermore, it has been observed that cultivated plants with a modification, which provides insect resistance, can be particularly susceptible to certain pests against which the produced toxin is not effective. Moreover, the pests can develop resistance against the toxin, which is produced by the plant.
- Accordingly, there is a need for pesticides and pesticidal mixtures for controlling pests on cultivated plants with at least one or even more modifications.
- In this connection, it is also an object of the invention to provide a pesticide or pesticidal mixture, which is suitable for controlling pests, which are resistant to the insecticidal trait of the cultivated plant. It is another object of the invention to provide a pesticide or pesticidal mixture, which prevents pests to become resistant to the insecticidal trait of the cultivated plant.
- Furthermore, it is an object of the invention to provide a pesticide or pesticidal mixture, which can be applied in lower dosage rates compared to other pesticides and pesticidal mixtures in order to avoid unfavorable environmental or toxicological effects.
- It is yet another object of the invention to provide a pesticide or pesticidal mixture, which improves the health of a plant, a process which is commonly and hereinafter referred to as “plant health”. The term plant health comprises various sorts of improvements of plants that are not connected to the control of pests and which do not embrace the reduction of negative consequences of harmful insects. The term “plant health” is to be understood to denote a condition of the plant and/or its products which is determined by several indicators alone or in combination with each other such as yield (e.g. increased biomass and/or increased content of valuable ingredients), plant vigor (e.g. improved plant growth and/or greener leaves (“greening effect”), quality (e.g. improved content or composition of certain ingredients) and tolerance to abiotic and/or biotic stress. The above identified indicators for the health condition of a plant may be interdependent or may result from each other.
- It has been found that the above objects can be achieved by methods applying or the use of a pesticidal active carboxamide compound I selected from
- i) compound i) of formula (I)
- ii) compound ii) of formula (Ia)
- iii) mixtures comprising the carboxamide compounds i) and ii),
-
- or the tautomers, enantiomers, diastereomers or salts thereof,
- alone or in mixtures comprising such pesticidal active carboxamide compound.
- Preferred methods and uses according to of this invention comprise compound i) of formula (I) as pesticidal active carboxamide compound I. Preferred embodiments of this invention are the methods or the use of the pesticidal active carboxamide compound i) of formula (I) or the tautomers, enantiomers, diastereomers or salts thereof, alone or in mixtures comprising such pesticidal active carboxamide compound.
- Other embodiments of this invention are the methods or the use of the pesticidal active carboxamide compound ii) of formula (Ia) or the tautomers, enantiomers, diastereomers or salts thereof, alone or in mixtures comprising such pesticidal active carboxamide compound.
- Still other embodiments of this invention are the methods or the use of pesticidal active mixtures comprising the carboxamide compounds i) of formula (I) and ii) of formula (Ia) or the tautomers, enantiomers, diastereomers or salts thereof, alone or in mixtures comprising such pesticidal active carboxamide compound mixtures.
- Unless explicitly said otherwise, the terms “compound i) of formula (I)”, “compound (ii) of formula (la), or “mixture comprising the carboxamide compounds (i) and (ii)” also include the respective salts, tautomers, stereoisomers, and N-oxides of the carboxamide compounds.
- In case of certain cultivated plants, the above objects may be achieved by the use or application of the pesticidal active carboxamide compound I, preferably compound i) of formula (I) alone. The application of the pesticidal active carboxamide compound I, preferably compound i) of formula (I) as only one active agent can be advantageous in terms of practicability and also in connection with insect resistance management.
- It has furthermore been found that the above objects can be achieved by a pesticidal mixture comprising the pesticidal active carboxamide compound I, preferably compound i) of formula (I) and another pesticidal active ingredient, whereas the uses and methods comprising the application of said mixture as defined hereinafter.
- In case that the pesticidal effectiveness of the pesticidal mixture of the invention as well as of the pesticidal active carboxamide compound I, preferably compound i) of formula (I) alone can be enhanced by the insecticidal trait of the plant, this may be considered as a synergistic effect.
- The application of a mixture comprising pesticidal active carboxamide compound I, preferably compound i) of formula (I), including the simultaneous, that is joint or separate, application of pesticidal active carboxamide compound I, preferably compound i) of formula (I) and the other pesticidal active ingredient or their successive application on cultivated plants may allow enhanced control of animal pests, compared to the control rates that are possible by application on non-cultivated plants.
- For certain plants with specific modifications as described herein after, the use of the pesticidal active carboxamide compound I, preferably compound i) of formula (I), alone may also display a synergistic effect between the trait of the cultivated plant and the applied pesticidal active carboxamide compound I, preferably compound i) of formula (I). For these plants with specific modifications, also the mixture comprising pesticidal active carboxamide compound I, preferably compound i) of formula (I), and another pesticidal active compound may advantageously be used.
- As mentioned above, the pesticidal active carboxamide compound I, preferably compound i) of formula (I), or a mixture comprising such pesticidal active carboxamide compound I, preferably compound i) of formula (I), may be useful in methods of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth, wherein the plant has at least one insecticidal trait, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- The carboxamide compound I
- Carboxamide derivatives showing generally pesticidal activity have been described previously. WO200573165 and WO2010018714 describe carboxamide compounds, their preparation and their use as pest control agents. WO2007013150, JP2011-157294, JP2011-157295 and JP2011-157296 describe mixtures of carboxamides with other active ingredients.
- Preparation of the pesticidal active carboxamide compound I, preferably compound i) of formula (I), can further be accomplished according to standard methods of organic chemistry, e.g. by the methods or working examples described in WO 2010/018857 without being limited to the routes given therein.
- The carboxamide compound i) of formula (I), which has been provisionally approved under the common name broflanilide, has been described in combination with fungicidal active compounds in PCT/EP2014/072189 or with insecticidal active compounds in PCT/EP2014/072183.
- However, methods and uses applying the pesticidal carboxamide compound I, preferably compound i) of formula (I), on cultivated plant, alone or in combination with selected other pesticidal active ingredients, have not been described previously.
- The prior art does not disclose such methods and uses of the pesticidal carboxamide compound I, preferably compound i) of formula (I), or pesticidal mixtures comprising such selected carboxamide compound on cultivated plant showing unexpected results.
- The carboxamide compound I, preferably the compound i) of formula (I), includes its tautomers, racemic mixtures, individual pure enantiomers and diasteroemers and the optically active mixtures.
- Pests
- The carboxamide compound i) of formula (I) is especially suitable for efficiently combating animal pests such as arthropods, gastropods and nematodes including but not limited to: insects from the order of Lepidoptera, for example Achroia grisella, Acleris spp. such as A. fimbriana, A. gloverana, A. variana; Acrolepiopsis assectella, Acronicta major, Adoxophyes spp. such as A. cyrtosema, A. orana; Aedia leucomelas, Agrotis spp. such as A. exclamationis, A. fucosa, A. ipsilon, A. orthogoma, A. segetum, A. subterranea; Alabama argillacea, Aleurodicus dispersus, Alsophlla pometaria, Ampelophaga rubiginosa, Amyelolis transitella, Anacampsis sarcitella, Anagasta kuehniella, Anarsia lineatella, Anisota senatoria, Antheraea pemyi, Anticarsia (=Thermesia) spp. such as A. gemmatalis; Apamea spp., Aproaerema modicella, Archips spp. such as A. argyrospila, A. fuscocupreanus, A. rosana, A. xyloseanus; Argyresthia conjugelia, Argyroploce spp., Argyrotaenia spp. such as A. velutinana; Athetis mindara, Austroasca viridigrisea, Autographa gamma, Autographa nigrisigna, Barathra brassicae, Bedellia spp., Bonagota salubricola, Borbo cinnara, Bucculatrix thurberiella, Bupalus piniarius, Busseola spp., Cacoecia spp. such as C. murinana, C. podana; Cactoblastis cactorum, Cadra cautella, Calingo braziliensis, Calopas theivora, Capua reticulana, Carposina spp. such as C. niponensis, C. sasald; Cephus spp., Chaetocnema aridula, Cheimatobia brumata, Chilo spp. such as C. lndicus, C. suppressalis, C. partellus; Choreutis pariana, Choristoneura spp. such as C. conflictana, C. fumiferana, C. longicellana, C. murinana, C. occidentalis, C. rosaceana; Chrysodeixis (=Pseudoplusia) spp. such as C. eriosoma, C. includens; Cirphis unipuncta, Clysia ambiguella, Cnaphalocerus spp., Cnaphalocroclis medinalis, Cnephasia spp., Cochyllis hospes, Coleophora spp., Colias eurytheme, Conopomorpha spp., Conotrachelus spp., Copitarsia spp., Corcyra cephalonica, Crambus caliginosellus, Crambus teterrellus, Crocidosema (=Epinotia) aporema, Cydalima (=Diaphania) perspectalis, Cydia (=Carpocapsa) spp. such as C. pomonella, C. latiferreana; Dalaca noctuides, Datana integerrima, Dasychira pinicola, Dendrolimus spp. such as D. pini, D. spectabllis, D. sibiricus; Desmia funeralis, Diaphania spp. such as D. nitidalis, D. hyalinata; Diatraea grandiosella, Diatraea saccharalis, Diphthera festiva, Earias spp. such as E. insulana, E. vittella; Ecdytolopha aurantianu, Egira (=Xylomyges) curialis, Elasmopalpus lignosellus, Eldana saccharin, Endopiza viteana, Ennomos subsignaria, Eoreuma lofiini, Ephestia spp. such as E. cautella, E. elutella, E. kuehniella; Epinotia aporema, Epiphyas postvittana, Erannis tiliaria, Erionota thrax, Etiella spp., Eulia spp., Eupoecilia ambiguella, Euproct chrysorrhoea, Euxoa spp., Evetria bouliana, Faronta albilinea, Feltia spp. such as F. subterranean; Galleria mellonella, Gracillaria spp., Grapholita spp. such as G. funebrana, G. moiesta, G. inopinata; Halysidota spp., Harrisina americana, Hedylepta spp., Helicoverpa spp. such as H. armigera (=Heliothis armigera), H. zea (=Heliothis zea); Heliothis spp. such as H. assulta, H. subflexa, H. virescens; Hellula spp. such as H. undalis, H. rogatalis; Helocoverpa gelotopoeon, Hemlleuca oliviae, Herpetogramma licarsisalis, Hibernia defoliaria, Hofmannophlla pseudospretella, Homoeosoma electellum, Homona magnanima, Hypena scabra, Hyphantria cunea, Hyponomeuta padella, Hyponomeuta malinellus, Kakivoria flavofasciata, Keiferia lycopersicella, Lambdina fiscellaria fiscellaria, Lambdina fiscellaria lugubrosa, Lamprosema indicata, Laspeyresia molesta, Leguminivora glycinivorella, Lerodea eufala, Leucinodes orbonalis, Leucoma salicis, Leucoptera spp. such as L. coffeella, L. scitella; Leuminivora lycinivorella, LithocollenS blancardella, Lithophane antennata, Llattia octo (=Amyna axis), Lobesia botrana, Lophocampa spp., Loxagrotis albicosta, Loxostege spp. such as L. sticticalis, L. cereralis; Lymantria spp. such as L. dispar, L. monacha; Lyonetia clerkella, Lyonetia prunifoliella, Malacosoma spp. such as M. americanum, M. californicum, M. constrictum, M. neustria; Mamestra spp. such as M. brassicae, M. configurata; Mamstra brassicae, Manduca spp. such as M. quinquemaculata, M. sexta; Marasmia spp, Marmara spp., Maruca testulalis, Megalopyge Janata, Melanchra picta, Melanitis leda, Mocis spp. such as M. lapites, M. repanda; Mocis latipes, Monochroa fragariae, Mythimna separata, Nemapogon cloacella, Neoleucinodes elegantalis, Nepytia spp., Nymphula spp., Oiketicus spp., Omiodes indicata, Omphisa anastomosalis, Operophtera brumata, Orgyia pseudotsugata, Oria spp., Orthaga thyrisalis, Ostrinia spp. such as O. nubilalis; Oulema oryzae, Paleacrita vernata, Panolis flammea, Parnara spp., Papaipema nebris, Papllio cresphontes, Paramyelois transitella, Paranthrene regalis, Paysandisia archon, Pectinophora spp. such as P. gossypiella; Peridroma saucia, Perileucoptera spp., such as P. coffeella; Phalera bucephala, Phryganidia californica, Phthorimaea spp. such as P. operculella; Phyllocnistis citrella, Phyllonorycter spp. such as P. blancardella, P. crataegella, P. issikii, P. ringoniella; Pieris spp. such as P. brassicae, P. rapae, P. napi; Pllocrocis tripunctata, Plathypena scabra, Platynota spp. such as P. flavedana, P. idaeusalis, P. stultana; Platyptllia carduidactyla, Plebejus argus, Plodia interpunctella, Plusia spp, Plutella maculipennis, Plutella xylostella, Pontia protodica, Prays spp., Prodenia spp., Proxenus lepigone, Pseudaletia spp. such as P. sequax, P. unipuncta; Pyrausta nubllalis, Rachiplusia nu, Richia albicosta, Rhizobius ventrals, Rhyacionia frustrana, Sabulodes aegrotata, Schizura concinna, Schoenobius spp., Schreckensteinia festaliella, Scirpophaga spp. such as S. incertulas, S. innotata; Scotia segetum, Sesamia spp. such as S. inferens, Seudyra subflava, Sitotroga cerealella, Sparganothis pilleriana, Spllonota lechriaspis, S. ocellana, Spodoptera (=Lamphygma) spp. such as S. cosmoides, S. eridania, S. exigua, S. frugiperda, S. latisfascia, S. littoralis, S. litura, S. omithogalli; Stigmella spp., Stomopteryx subsecivella, Strymon bazochii, Sylepta derogata, Synanthedon spp. such as S. exitiosa, Tecia solanivora, Telehin licus, Thaumatopoea pityocampa, Thaumatotibia (=Cryptophlebia) leucotreta, Thaumetopoea pityocampa, Thecla spp., Theresimima ampelophaga, Thyrinteina spp, Tildenia inconspicuella, Tinea spp. such as T. cloacella, T. pellionella; Tineola bisselliella, Tortrix spp. such as T. viridana; Trichophaga tapetzella, Trichoplusia spp. such as T. ni; Tuta (=Scrobipalpula) absoluta, Udea spp. such as U. rubigalis, U. rubigalis; Virachola spp., Yponomeuta padella, and Zeiraphera canadensis;
- insects from the order of Coleoptera, for example Acalymma vittatum, Acanthoscehdes obtectus, Adoretus spp., Agelastica alni, Agrilus spp. such as A. anxius, A. planipennis, A. sinuatus; Agriotes spp. such as A. fuscicollis, A. lineatus, A. obscurus; Alphitobius diaperinus, Amphimallus solstitialis, Anisandrus dispar, AmSoplia austriaca, Anobium punctatum, Anomala corpulenta, Anomala rufocuprea, Anoplophora spp. such as A. glabripennis; Anthonomus spp. such as A. eugenil, A. grandis, A. pomorum; Anthrenus spp., Aphthona euphoridae, Apion spp., Apogonia spp., Athous haemorrhoidalis, Atomaria spp. such as A. linearis; Attagenus spp., Aulacophora femoralis, Blastophagus piniperda, Blitophaga undata, Bruchidius obtectus, Bruchus spp. such as B. lentis, B. pisorum, B. rufimanus; Bycfiscus betulae, Callidiellum rufipenne, Callopistria floridensis, Callosobruchus chinensis, Cameraria ohridella, Cassida nebulosa, Cerotoma trifurcata, Cetonia aurata, Ceuthorhynchus spp. such as C. assimllis, C. napi; Chaetocnema tibialis, Cleonus mendicus, Conoderus spp. such as C. vespertinus; Conotrachelus nenuphar, Cosmopolites spp., Costelytra zealandica, Criocenis asparagi, Cryptolestes ferrugineus, Cryptorhynchus lapathl, Ctenicera spp. such as C. destructor; Curculio spp., Cylindrocopturus spp., Cyclocephala spp., Dactylispa balyi, Dectes texanus, Dermestes spp., Diabrotica spp. such as D. undecimpunctata, D. speciosa, D. longicornis, D. semipunctata, D. virgifera; Diaprepes abbreviates, Dichocroais spp., Dicladispa armigera, Diloboderus abderus, Diocalandra frumenfi (Diocalandra stigmaticollis), Enaphalodes rufulus, Epilachna spp. such as E. varivestis, E. vigintioctomaculata; Epitrix spp. such as E. hirtipennis, E. simllaris; Eutheola humilis, Eutinobothrus brasiliensis, Faustinus cubae, Gibbium psylloides, Gnathocerus cornutus, Hellula undalis, Heteronychus arator, Hylamorpha elegans, Hylobius abietis, Hylotrupes bajulus, Hypera spp. such as H. brunneipennis, H. postica; Hypomeces squamosus, Hypothenemus spp., lps typographus, Lachnosterna consanguinea, Lasioderma serricome, Latheticus oryzae, Lathridius spp., Lema spp. such as L. bilineata, L. melanopus; Leptinotarsa spp. such as L. decem lineata; Leptispa pygmaea, Limonius californicus, Lissorhoptrus olyzophllus, Lixus spp., Luperodes spp., Lyctus spp. such as L. bruneus; Liogenys fuscus, Macrodactylus spp. such as M. subspinosus; Maladera matrida, Megaplatypus mutates, Megascells spp., Melanotus communis, Meligethes spp. such as M. aeneus; Melolontha spp. such as M. hippocastani, M. melolontha; Metamasius hemipterus, Microtheca spp., Migdolus spp. such as M. fryanus, Monochamus spp. such as M. altematus; Naupactus xanthographus, Niptus hololeucus, Oberia brevis, Oemona hirta, Oryctes rhinoceros, Oryzaephilus surinamensis, Oryzaphagus oryzae, Otiorrhynchus sulcatus, Otiorrhynchus ovatus, Otiorrhynchus sulcatus, Oulema melanopus, Oulema oryzae, Oxycetonia jucunda, Phaedon spp. such as P. brassicae, P. cochleariae; Phoracantha recurva, Phyllobius pyri, Phyllopertha horticola, Phyllophaga spp. such as P. helleri; Phyllotreta spp. such as P. chrysocephala, P. nemorum, P. striolata, P. vittula; Phyllopertha horticola, Popillia japonica, Premnotrypes spp., Psacothea hilaris, Psylliodes chrysocephala, Prostephanus truncates, Psylliodes spp., Ptinus spp., Pulga saltona, Rhizopertha dominica, Rhynchophorus spp. such as R. billineatus, R. ferrugineus, R. palmarum, R. phoenicis, R. vulneratus; Saperda candida, Scolytus schevyrewi, Scyphophorus acupunctatus, Sitona lineatus, Sitophilus spp. such as S. granaria, S. oryzae, S. zeamais; Sphenophorus spp. such as S. Levis; Stegobium paniceum, Sternechus spp. such as S. subsignatus; Strophomorphus ctenotus, Symphyletes spp., Tanymecus spp., Tenebrio molitor, Tenebrioides mauretanicus, Tribolium spp. such as T. castaneum; Trogoderma spp., Tychius spp., Xylotrechus spp. such as X. pyrrhoderus; and, Zabrus spp. such as Z. tenebrioides;
- insects from the order of Diptera for example Aedes spp. such as A. aegypti, A. albopictus, A. vexans; Anastrepha ludens, Anopheles spp. such as A. albimanus, A. crucians, A. freeborni, A. gambiae, A. leucosphyrus, A. maculipennis, A. minimus, A. quadrimaculatus, A. sinensis; Bactrocera invadens, Bibio hortulanus, Calliphora erythrocephala, Calliphora vicina, Ceratitis capitata, Chrysomyia spp. such as C. bezziana, C. hominivorax, C. macellaria; Chrysops atlanticus, Chrysops Chrysops sllacea, Cochliomyia spp. such as C. hominivorax; Contarinia spp. such as C. sorghicola; Cordylobia anthropophaga, Culex spp. such as C. nigripalpus, C. pipiens, C. quinquefasciatus, C. tarsalis, C. tritaeniorhynchus; Culicoides furens, Cuilseta inornata, Culiseta melanura, Cuterebra spp., Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Dasineura oxycoccana, Della spp. such as D. antique, D. coarctata, D. platura, D. radicum; Dermatobia hominis, Drosophila spp. such as D. suzukii, Fannia spp. such as F. canicularis; Gastraphllus spp. such as G. intestinalis; Geomyza tipunctata, Glossina spp. such as G. fuscipes, G. morsitans, G. palpalis, G. tachinoides; Haematobiairritans, Haplodiplosis equestris, Hippelates spp., Hylemyia spp. such as H. platura; Hypoderma spp. such as H. lineata; Hyppobosca spp., Hydrellia philippina, Leptoconops torrens, Liriomyza spp. such as L. sativae, L. trifolii; Lucllia spp. such as L. caprin, L. cuprina, L. sericata; Lycoria pectoralis, Mansonia titillanus, Mayetiola spp. such as M. destructor; Musca spp. such as M. autumnalis, M. domestica; Muscina stabulans, Oestrus spp. such as O. ovis; Opomyza florum, Oscinella spp. such as O. frit; Orseolia oryzae, Pegomya hysocyami, Phlebotomus argentipes, Phorbia spp. such as P. antiqua, P. brassicae, P. coarctata; Phytomyza gymnostoma, Prosimulium mixtum, Psila rosae, Psorophora columbiae, Psorophora discolor, Rhagoletis spp. such as R. cerasi, R. cingulate, R. indifferens, R. mendax, R. pomonella; Rivellia quadrifasciata, Sarcophaga spp. such as S. haemorrhoidalis; Simulium vittatum, Sitodiplosis mosellana, Stomoxys spp. such as S. calcitrans; Tabanus spp. such as T. atratus, T. bovinus, T. lineola, T. similis; Tannia spp., Thecodiplosis japonensis, Tipula oleracea, Tipula paludosa, and Wohlfahrtia spp;
- insects from the order of Thysanoptera for example, Baliothrips biformis, Dichromothnps corbetti, Dichromothrips ssp., Echinothrips americanus, Enneothrips flavens, Frankliniella spp. such as F. fusca, F. occidentalis, F. tritici; Heliothnps spp., Hercinothrips femoralis, Kakothrips spp., Microcephalothrips abdominalis, Neohydatothnps samayunkur, Pezothrips kellyanus, Rhipiphorothrips cruentatus, Scirtothnps spp. such as S. citri, S. dorsalis, S. perseae; Stenchaetothrips spp, Taeniothnps cardamom, Taeniothrips inconsequens, Thrips spp. such as T. imagines, T. hawallensis, T. oryzae, T. palmi, T. parvispinus, T. tabaci;
- insects from the order of Hemiptera for example, Acizzia jamatonica, Acrosternum spp. such as A. Mare; Acyrthosipon spp. such as A. onoboichis, A. pisum; Adelges laricis, Adelges tsugae, Adelphocoris spp., such as A. rapidus, A. superbus; Aeneolamia spp., Agonoscena spp., Aulacorthum solani, Aleurocanthus woglumi, Aleurodes spp., Aleurodicus disperses, Aleurolobus barodensis, Aleurothrixus spp., Amrasca spp., Anasa tristis, Antestiopsis spp., Anuraphis cardui, Aonidiella spp., Aphanostigma Aphidula nasturtil, Aphis spp. such as A. craccivora, A. fabae, A. forbesi, A. gossypil A. grossulariae, A. maidiradicis, A. pomi, A. sambuci, A. schneideri, A. spiraecola; Arboridia apicalis, Arilus critatus, Aspidiella spp., Aspidiotus spp., Atanus spp., Aulacaspis yasumatsui, Aulacorthum solani, Bactericera cockerelli (Paratrioza cockerelli), Bemisia spp. such as B. argentifolil, B. tabaci (Aleurodes tabaci); Blissus spp. such as B. leucopterus; Brachycaudus spp. such as B. cardui, B. helichlysi, B. persicae, B. prunicola; Brachycolus spp., Brachycorynella asparagi, Brevicoryne brassicae, Cacopsylla spp. such as C. fulguralis, C. pyricola (Psylla piri); Calligypona marginata, Calocoris spp., Campylomma livida, Capitophorus horni, Cameocephala fulgida, Cavelerius spp., Ceraplastes spp., Ceratovacuna lanigera, Ceroplastes ceriferus, Cerosipha gossypil, Chaetosiphon fragaefolil, Chionaspis tegalensis, Chlorita Chromaphis juglandicola, Chlysomphalus ficus, Cicadulina mbila, mex spp. such as C. hemipterus, C. lectularius; Coccomytilus Coccus spp. such as C. hespendum, C. pseudomagnoliarum; Corythucha arcuata, Creontiades Cryptomyzus nbis, Chlysomphalus aonidum, Cryptomyzus Ctenalytaina spatulata, Cyrtopeltis notatus, Dalbulus spp., Dasynus piperis, Dialeurodes spp. such as D. citrifolii; Dalbulus maidis, Diaphorina spp. such as D. citri; Diaspis spp. such as D. bromeliae; Dichelops furcatus, Diconocoris hewetti, Doralls spp., Dreyfusia nordmannianae, Dreyfusia piceae, Drosicha spp., Dysaphis spp. such as D. plantaginea, D. gyri, D. radicola; Dysaulacorthum pseudosolani, Dysdercus spp. such as D. cingulatus, D. intermedius; Dysmicoccus spp., Edessa spp., Geocoris spp., Empoasca spp. such as E. fabae, E. solana; Epidiaspis leperii, Enbsoma spp. such as E. lanigerum, E. pyricola; Erythroneura spp., Eurygaster spp. such as E. integriceps; Euscells bilobatus, Euschistus spp. such as E. heros, E. impictiventris, E. servus; Fionnia theae, Geococcus coffeae, Glycaspis brimblecombel, Halyomorpha spp. such as H. halys; Heliopeltis spp., Homalodisca vitripennis (=H. coagulata), Horcias nobllellus, Hyalopterus pruni, Hyperomyzus lactucae, Icelya spp. such as I. purchase; Idiocerus spp., Idioscopus spp., Laodelphax striatellus, Lecaniurn spp., Lecanoideus floccissimus, Lepidosaphes spp. such as L. ulmi; Leptocorisa spp., Leptoglossus phyllopus, Lipaphis Lygus spp. such as L. hesperus, L. lineolaris, L. pratensis; Maconellicoccus hirsutus, Marchalina hellenica, Macropes excavatus, Macrosiphum spp. such as M. rosae, M. avenae, M. euphorbiae; Macrosteles quadrilineatus, Mahanarva fimbriolata, Megacopta cribraria, Megoura viciae, Melanaphis pyrarius, Melanaphis sacchari, Melanocallis (=Tinocallis) coyaefoliae, Metcafiella spp., Metopolophium dirhodum, Monellia costalis, Monelliopsis pecanis, Myzocallls coryli, Murgantia spp., Myzus spp. such as M. ascalonicus, M. cerasi, M. nicotianae, M. persicae, M. varians; Nasonovia ribis nigri, Neotoxoptera formosana, Neomegalotomus spp, Nephotettix spp. such as N. malayanus, N. nigropictus, N. parvus, N. virescens; Nezara spp. such as N. viridula; Nilaparvata lugens, Nysius huttoni, Oebalus spp. such as O. pugnax; Oncometopia spp., Orthezia praelonga, Oxycaraenus hyalinipennis, Para bemisia myricae, Parlatona spp., Parthenolecanium spp. such as P. corm, P. persicae; Pemphigus spp. such as P. bursarius, P. populivenae; Peregrinus maidis, Perkinsiella saccharicida, Phenacoccus spp. such as P. aceris, P. gossypii; Phloeomyzus passerimi, Phorodon humuli, Phylloxera spp. such as P. devastatrix, Piesma quadrata, Piezodorus spp. such as P. gulldimi; Pinnaspis aspidlistrae, Planococcus spp. such as P. citri, P. ficus; Prosapia bicincta, Protopulvinana pyriformis, Psallus senatus, Pseudacysta persea, Pseudaulacaspis pentagon, Pseudococcus spp. such as P. comstocki; Psylla spp. such as P. mali; Pteromalus spp., Pulvinana amygdali, Pyrilla spp., Quadraspidiotus spp., such as Q. perniciosus; Quesada gigas, Rastrococcus spp., Reduvius semils, Rhizoecus americanus, Rhodnius spp., Rhopalomyzus ascalonicus, Rhopalosiphum spp. such as R. pseudobrassicas, R. insertum, R. maidis, R. padi; Sagalodes spp., Sahlbergella singularis, Saissetia spp., Sappaphis mala, Sappaphis mall, Scaptocoris spp., Scaphoides titanus, Schizaphis graminum, Schizoneura lanuginosa, Scotinophora spp., Selenaspidus articulatus, Sitobion avenae, Sogata spp., Sogatella furcifera, Solubea insularis, Spissistilus festinus (=Stictocephala festina), Stephanitis nashi, Stephanitis pyrioides, Stephanitis takeyai, Tenalaphara malayensis, Tetraleurodes perseae, Therioaphis maculate, Thyanta spp. such as T. accerra, T. perditor; Tibraca spp., Tomaspis spp., Toxoptera spp. such as T. aurantii; Trialeurodes spp. such as T. abutilonea, T. ricin, T. vaporariorum; Triatoma spp., Trioza spp., Typhlocyba spp., Unaspis spp. such as U. citri, U. yanonensis; and Viteus vitifolil;
- Insects from the order Hymenoptera for example Acanthomyops interjectus, Athalia rosae, Atta spp. such as A. capiguara, A. cephalotes, A. cephalotes, A. laevigata, A. robusta, A. sexdens, A. texana, Bombus spp., Brachymyrmex spp., Camponotus spp. such as C. floridanus, C. pennsylvanicus, C. modoc; Cardiocondyla nuda, Challbion sp, Crematogaster spp., Dasymutllla occidentalis, Diprion spp., Dolichovespula maculata, Dorymyrmex spp., Dryocosmus kuriphilus, Formica spp., Hoplocampa spp. such as H. minuta, H. testudinea; Iridomyrmex humilis, Lasius spp. such as L. niger, Linepithema humile, Liometopum spp., Leptocybe invasa, Monomorium spp. such as M. pharaonis, Monomorium, Nylandria fulva, Pachycondyla chinensis, Paratrechina longicornis, Paravespula spp., such as P. germanica, P. pennsylvanica, P. vulgaris; Pheidole spp. such as P. megacephala; Pogonomyrmex spp. such as P. barbatus, P. californicus, Pollstes rubiginosa, Prenolepis impairs, Pseudomyrmex gracilis, Schelipron spp., Sirex cyaneus, Solenopsis spp. such as S. geminata, Sinvicta, S. molesta, S. richteri, S. xylonl, Sphecius speciosus, Sphex spp., Tapinoma spp. such as T. melanocephalum, T. sessile; Tetramorium spp. such as T. caespitum, T. bicarinatum, Vespa spp. such as V. crabro; Vespula spp. such as V. squamosal; Wasmannia auropunctata, Xylocopa sp;
- Insects from the order Orthoptera for example Acheta domesticus, Calliptamus italicus, Chortoicetes terminifera, Ceuthophilus spp., Diastrammena asynamora, Dociostaurus maroccanus, Gryllotalpa spp. such as G. africana, G. gryllotalpa; Gryllus spp., Hieroglyphus daganensis, Kraussaria angulifera, Locusta spp. such as L. migratoria, L. pardalina; Melanoplus spp. such as M. bivittatus, M. femurrubrum, M. mexicanus, M. sanguinipes, M. spretus; Nomadacris septemfasciata, Oedaleus senegalensis, Scapteriscus spp., Schistocerca spp. such as S. Americana, S. gregaria, Stemopelmatus spp., Tachycines asynamorus, and Zonozerus variegatus;
- Pests from the Class Arachnida for example Acari, e.g. of the families Argasidae, Ixodidae and Sarcoptidae, such as Amblyomma spp. (e.g. A. americanum, A. variegatum, A. maculatum), Argas spp. such as A. persicu), Boophilus spp. such as B. annulatus, B. decoloratus, B. microplus, Dermacentor spp. such as D. silvarum, D. andersom, D. variabilis, Hyalomma spp. such as H. truncatum, Ixodes spp. such as I. ricinus, I. rubicundus, I. scapularis, I. holocyclus, I. pacificus, Rhipicephalus sanguineus, Ornithodorus spp. such as O. moubata, O. hermsi, O. turicata, Ornithonyssus bacoti, Otobius megnini, Dermanyssus gallinae, Psoroptes spp. such as P. ovis, Rhipicephalus spp. such as R. sanguineus, R. appendiculatus, Rhipicephalus evertsi, Rhizoglyphus spp., Sarcoptes spp. such as S. Scabiei; and Family Eriophyidae including Aceria spp. such as A. sheldoni, A. anthocoptes, Acallitus spp., Aculops spp. such as A. lycopersici, A. pelekassi; Aculus spp. such as A. schlechtendali; Colomerus vitis, Epitrimerus gyri, Phyllocoptruta oleivora; Eriophytes ribis and Eriophyes spp. such as Eriophyes sheldoni; Family Tarsonemidae including Hemitarsonemus spp., Phytonemus pallidus and Polyphagotarsonemus latus, Stenotarsonemus spp. Steneotarsonemus spinki; Family Tenuipalpidae including Brevipalpus spp. such as B. phoenicis; Family Tetranychidae including Eotetranychus spp., Eutetranychus spp., Oligonychus spp., Petrobia latens, Tetranychus spp. such as T. cinnabarinus, T. evansi, T. kanzawai, T, pacificus, T. phaseulus, T. telarius and T. urticae; Bryobia praetiosa; Panonychus spp. such as P. ulmi, P. citri; Metatetranychus spp. and Oligonychus spp. such as O. pratensis, O. perseae, Vasates lycopersici; Raoiella indica, Family Carpoglyphidae including Carpoglyphus spp.; Penthaleidae spp. such as Halotydeus destructor, Family Demodicidae with species such as Demodex spp.; Family Trombicidea including Trombicula spp.; Family Macronyssidae including Ornothonyssus spp.; Family Pyemotidae including Pyemotes tritici; Tyrophagus putrescentiae; Family Acaridae including Acarus siro; Family Araneida including Latrodectus mactans, Tegenaria agrestis, Chiracanthium sp, Lycosa sp Achaearanea tepidariorum and Loxosceles reclusa;
- Pests from the Phylum Nematoda, for example, plant parasitic nematodes such as root-knot nematodes, Meloidogyne spp. such as M. hapla, M. incognita, M. Javanica; cyst-forming nematodes, Globodera spp. such as G. rostochiensis; Heterodera spp. such as H. avenae, H. glycines, H. schachtil, H. trifolii; Seed gall nematodes, Anguina spp.; Stem and foliar nematodes, Aphelenchoides spp. such as A. besseyi; Sting nematodes, Belonolaimus spp. such as B. longicaudatus; Pine nematodes, Bursaphelenchus spp. such as B. lignicolus, B. xylophilus; Ring nematodes, Criconema spp., Criconemella spp. such as C. xenoplax and C. omata; and, Criconemoides spp. such as Criconemoides informis; Mesocriconema spp.; Stem and bulb nematodes, Ditylenchus spp. such as D. destructor, D. dipsaci; Awl nematodes, Dolichodorus spp.; Spiral nematodes, Hellocotylenchus multicinctus; Sheath and sheathoid nematodes, Hemicycliophora spp. and Hemicriconemoides spp.; Hirshmanniella spp.; Lance nematodes, Hoploaimus spp.; False rootknot nematodes, Nacobbus spp.; Needle nematodes, Longidorus spp. such as L. elongatus; Lesion nematodes, Pratylenchus spp. such as P. brachyurus, P. neglectus, P. penetrans, P. curvitatus, P. goodeyi; Burrowing nematodes, Radopholus spp. such as R. similis; Rhadopholus spp.; Rhodopholus spp.; Reniform nematodes, Rotylenchus spp. such as R. robustus, R. reniformis; Scutellonema spp.; Stubby-root nematode, Trichodorus spp. such as T. obtusus, T. primitivus; Paratrichodorus spp. such as P. minor; Stunt nematodes, Tylenchorhynchus spp. such as T. claytoni, T. dubius; Citrus nematodes, Tylenchulus spp. such as T. semipenetrans; Dagger nematodes, Xiphinema spp.; and other plant parasitic nematode species;
- Insects from the order Isoptera for example Calotermes flavicollis, Coptotermes spp. such as C. formosanus, C. gestroi, C. acinaciformis; Cornitermes cumulans, Cryptotermes spp. such as C. brevis, C. cavifrons; Globitermes sulfureus, Heterotermes spp. such as H. aureus, H. longiceps, H. tenuis; Leucotermes flavipes, Odontotermes spp., Incisitermes spp. such as I. minor, I. Snyder, Marginitermes hubbardi, Mastotermes spp. such as M. darwiniensiS Neocapritermes spp. such as N. opacus, N. parvus; Neotermes spp., Procornitermes spp., ZootermopsiS spp. such as Z. angusticollis, Z. nevadensis, Reticulitermes spp. such as R. hesperus, R. tibialis, R. speratus, R. flavipes, R. grassei, R. lucifugus, R. santonensis, R. virginicus; Termes natalensis,
- Insects from the order Blattaria for example Blatta spp. such as B. orientails, B. lateralis; Blattella spp. such as B. asahinae, B. germanica; Leucophaea maderae, Panchlora nivea, Periplaneta spp. such as P. americana, P. australasiae, P. brunnea, P. fuligginosa, P. japonica; Supella longipaipa, Parcoblatta pennsylvanica, Eurycotis floridana, Pycnoscelus surinamensis,
- Insects from the order Siphonoptera for example Cediopsylla simples, Ceratophyllus spp., Ctenocephalides spp. such as C. fells, C. canis, Xenopsylla cheopis, Pulex irritans, Trichodectes canis, Tunga penetrans, and Nosopsyllus fasciatus,
- Insects from the order Thysanura for example Lepisma saccharin, Ctenolepisma urban, and Thermobia domestica,
- Pests from the class Chilopoda for example Geophilus spp., Scutigera spp. such as Scutigera coleoptrata;
- Pests from the class Diplopoda for example Blaniulus guttulatus, Julus spp., Narceus spp.,
- Pests from the class Symphyla for example Scutigerella immaculata,
- Insects from the order Dermaptera, for example Forficula auricularia,
- Insects from the order Collembola, for example Onychiurus spp., such as Onychiurus armatus,
- Pests from the order Isopoda for example, Armadillidium vulgare, Oniscus asellus, Porcellio scaber,
- Insects from the order Phthiraptera, for example Damalinia spp., Pediculus spp. such as Pediculus humanus capitis, Pediculus humanus corporis, Pediculus humanus humanus; Pthirus pubis, Haematopinus spp. such as Haematopinus eurysternus, Haematopinus suis; Linognathus spp. such as Linognathus vituli; Bovicola bovis, Menopon gallinae, Menacanthus stramineus and Solenopotes capillatus, Trichodectes spp.,
- Examples of further pest species which may be controlled by the compound I, preferably compound i) of formula (I) include: from the Phylum Mollusca, class Bivalvia, for example, Dreissena spp.; class Gastropoda, for example, Arion spp., Biomphalaria spp., Bulinus spp., Deroceras spp., Galba spp., Lymnaea spp., Oncomelania spp., Pomacea canaliclata, Succinea spp.; from the class of the helminths, for example, Ancylostoma duodenale, Ancylostoma ceylanicum, Acylostoma braziliensis, Ancylostoma spp., Ascaris lumbricoides, Ascaris spp., Brugia malap, Brugia timon, Bunostomum spp., Chabertia spp., Cionorchis spp., Cooperia spp., Dicrocoelium spp., Dictyocaulus filaria, Diphyllobothrium latum, Dracunculus medinensis, Echinococcus granulosus, Echinococcus multilocularis, Enterobius vermicularis, Faciola spp., Haemonchus spp. such as Haemonchus contortus; Heterakis spp., Hymenolepis nana, Hyostrongulus spp., Loa Loa, Nematodirus spp., Oesophagostomum spp., Opisthorchis spp., Onchocerca volvulus, Ostertagia spp., Paragonimus spp., Schistosomen spp., Strongyloides fuelleborm, Strongyloides stercora lis, Stronyloides spp., Taenia saginata, Taenia solium, Trichinella spiralis, Trichinella nativa, Trichinella britow, Trichinella nelsoni, Trichinella pseudopsiralis, Trichostrongulus spp., Trichuris trichiura, Wuchereria bancrofii.
- Besides compound i) of formula (I) also the carboxamide compound ii) of formula (Ia) and mixtures comprising compound i) of formula (I) and compound ii) of formula (Ia) are suitable for efficiently combating animal pests such as arthropods, gastropods and nematodes as set out above.
- For the avoidance of doubt: Mixtures comprising the carboxamide compounds i) and ii) are mixtures comprising both compound i) of formula (I) and compound ii) of formula (Ia).
- Application Methods, Plants and Crops
- The compounds I, preferably compound i) of formula (I), are suitable for use in protecting crops, plants, plant propagation materials, such as seeds, or its locus of growth, from attack or infestation by animal pests. Therefore, the present invention also relates to a plant protection method, which comprises contacting crops, plants, plant propagation materials, such as seeds, or its locus of growth, to be protected from attack or infestation by animal pests, with a pesticidally effective amount of the compound I, preferably compound i) of formula (I).
- The compound I, preferably compound i) of formula (I), are also suitable for use in combating or controlling animal pests.
- Therefore, the present invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, such as seeds, or soil, or the area, material or environment in which the animal pests are growing or may grow, with a pesticidally effective amount of the compound i) of formula (I).
- The present invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, such as seeds, or soil, or the area, material or environment in which the animal pests are growing or may grow, with a pesticidally effective amount of compound ii) of formula (Ia).
- The present invention also relates to a method of combating or controlling animal pests, which comprises contacting the animal pests, their habitat, breeding ground, or food supply, or the crops, plants, plant propagation materials, such as seeds, or soil, or the area, material or environment in which the animal pests are growing or may grow, with a pesticidally effective amount of mixtures comprising the carboxamide compounds i) and ii).
- The compounds I, preferably compound i) of formula (I), are effective through both contact and ingestion. Furthermore, the compounds I, preferably compound i) of formula (I), can be applied to any and all developmental stages, such as egg, larva, pupa, and adult.
- The compound I, preferably compound i) of formula (I), can be applied as such or in form of compositions comprising them as defined above. Furthermore, the compound I, preferably compound i) of formula (I), can be applied together with a mixing partner as defined above or in form of compositions comprising said mixtures as defined above. The components of said mixture can be applied simultaneously, jointly or separately, or in succession, that is immediately one after another and thereby creating the mixture “in situ” on the desired location, e.g. the plant, the sequence, in the case of separate application, generally not having any effect on the result of the control measures.
- The application can be carried out both before and after the infestation of the crops, plants, plant propagation materials, such as seeds, soil, or the area, material or environment by the pests.
- Suitable application methods include inter alia soil treatment, seed treatment, in furrow application, and foliar application. Soil treatment methods include drenching the soil, drip irrigation (drip application onto the soil), dipping roots, tubers or bulbs, or soil injection. Seed treatment techniques include seed dressing, seed coating, seed dusting, seed soaking, and seed pelleting. In furrow applications typically include the steps of making a furrow in cultivated land, seeding the furrow with seeds, applying the pesticidally active compound I, preferably compound i) of formula (I), to the furrow, and closing the furrow. Foliar application refers to the application of the pesticidally active compound I, preferably compound i) of formula (I), to plant foliage, e.g. through spray equipment. For foliar applications, it can be advantageous to modify the behavior of the pests by use of pheromones in combination with the compound I, preferably compound i) of formula (I). Suitable pheromones for specific crops and pests are known to a skilled person and publicly available from databases of pheromones and semiochemicals, such as http://www.pherobase.com.
- As used herein, the term “contacting” includes both direct contact (applying the compounds/mixtures/compositions directly on the animal pest or plant—typically to the foliage, stem or roots of the plant) and indirect contact (applying the compounds/mixtures/compositions to the locus, i.e. habitat, breeding ground, plant, seed, soil, area, material or environment in which a pest is growing or may grow, of the animal pest or plant).
- The term “animal pest” includes arthropods, gastropods, and nematodes. Preferred animal pests according to the invention are arthropods, preferably insects and arachnids, in particular insects. Insects, which are of particular relevance for crops, are typically referred to as crop insect pests.
- The term “crop” refers to both, growing and harvested crops.
- The term “plant” includes cereals, e.g. durum and other wheat, rye, barley, triticale, oats, rice, or maize (fodder maize and sugar maize/sweet and field corn); beet, e.g. sugar beet or fodder beet; fruits, such as pomes, stone fruits or soft fruits, e.g. apples, pears, plums, peaches, nectarines, almonds, cherries, papayas, strawberries, raspberries, blackberries or gooseberries; leguminous plants, such as beans, lentils, peas, alfalfa or soybeans; oil plants, such as rapeseed (oilseed rape), turnip rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palms, ground nuts or soybeans; cucurbits, such as squashes, pumpkins, cucumber or melons; fiber plants, such as cotton, flax, hemp or jute; citrus fruit, such as oranges, lemons, grapefruits or mandarins; vegetables, such as eggplant, spinach, lettuce (e.g. iceberg lettuce), chicory, cabbage, asparagus, cabbages, carrots, onions, garlic, leeks, tomatoes, potatoes, cucurbits or sweet peppers; lauraceous plants, such as avocados, cinnamon or camphor; energy and raw material plants, such as corn, soybean, rapeseed, sugar cane or oil palm; tobacco; nuts, e.g. walnuts; pistachios; coffee; tea; bananas; vines (table grapes and grape juice grape vines); hop; sweet leaf (also called Stevia); natural rubber plants or ornamental and forestry plants, such as flowers (e.g. carnation, petunias, geranium/pelargoniums, pansies and impatiens), shrubs, broad-leaved trees (e.g. poplar) or evergreens, e.g. conifers; eucalyptus; turf; lawn; grass such as grass for animal feed or ornamental uses. Preferred plants include potatoes sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rapeseed, legumes, sunflowers, coffee or sugar cane; fruits; vines; ornamentals; or vegetables, such as cucumbers, tomatoes, beans or squashes.
- The term “plant” is to be understood as including wild type plants and plants, which have been modified by either conventional breeding, or mutagenesis or genetic engineering, or by a combination thereof.
- Plants, which have been modified by mutagenesis or genetic engineering, and are of particular commercial importance, include alfalfa, rapeseed (e.g. oilseed rape), bean, carnation, chicory, cotton, eggplant, eucalyptus, flax, lentil, maize, melon, papaya, petunia, plum, poplar, potato, rice, soybean, squash, sugar beet, sugarcane, sunflower, sweet pepper, tobacco, tomato, and cereals (e.g. wheat), in particular maize, soybean, cotton, wheat, and rice. In plants, which have been modified by mutagenesis or genetic engineering, one or more genes have been mutagenized or integrated into the genetic material of the plant. The one or more mutagenized or integrated genes are preferably selected from pat, epsps, cry1Ab, bar, cry1Fa2, cry1Ac, cry34Ab1, cry35AB1, cry3A, cryF, cry1F, mcry3a, cry2Ab2, cry3Bb1, cry1A.105, dfr, barnase, vip3Aa20, barstar, als, bxn, bp40, asn1, and ppo5. The mutagenesis or integration of the one or more genes is performed in order to improve certain properties of the plant. Such properties, also known as traits, include abiotic stress tolerance, altered growth/yield, disease resistance, herbicide tolerance, insect resistance, modified product quality, and pollination control. Of these properties, herbicide tolerance, e.g. imidazolinone tolerance, glyphosate tolerance, or glufosinate tolerance, is of particular importance. Several plants have been rendered tolerant to herbicides by mutagenesis, for example Clearfield® oilseed rape being tolerant to imidazolinones, e.g. imazamox. Alternatively, genetic engineering methods have been used to render plants, such as soybean, cotton, corn, beets and oil seed rape, tolerant to herbicides, such as glyphosate and glufosinate, some of which are commercially available under the trade names RoundupReady® (glyphosate) and LibertyLink® (glufosinate). Furthermore, insect resistance is of importance, in particular lepidopteran insect resistance and coleopteran insect resistance. Insect resistance is typically achieved by modifying plants by integrating cry and/or vip genes, which were isolated from Bacillus thuringiensis (Bt), and code for the respective Bt toxins. Genetically modified plants with insect resistance are commercially available under trade names including WideStrike®, Bollgard®, Agrisure®, Herculex®, YieldGard®, Genuity®, and Intacta®. Plants may be modified by mutagenesis or genetic engineering either in terms of one property (singular traits) or in terms of a combination of properties (stacked traits). Stacked traits, e.g. the combination of herbicide tolerance and insect resistance, are of increasing importance. In general, all relevant modified plants in connection with singular or stacked traits as well as detailed information as to the mutagenized or integrated genes and the respective events are available from websites of the organizations “International Service for the Acquisition of Agri-biotech Applications (ISAAA)” (http://www.isaaa.org/gmapprovaldatabase) and “Center for Environmental Risk Assessment (CERA)” (http://cera-grinc.org/GMCropDatabase).
- The term “plant propagation material” refers to all the generative parts of the plant such as seeds and vegetative plant material such as cuttings and tubers (e.g. potatoes), which can be used for the multiplication of the plant. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants. Seedlings and young plants, which are to be transplanted after germination or after emergence from soil, may also be included. These plant propagation materials may be treated prophylactically with a plant protection mixture either at or before planting or transplanting.
- The term “seed” embraces seeds and plant propagules of all kinds including but not limited to true seeds, seed pieces, suckers, corms, bulbs, fruit, tubers, grains, cuttings, cut shoots and the like, and means in a preferred embodiment true seeds.
- In general, “pesticidally effective amount” means the amount of active ingredient needed to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target organism. The pesticidally effective amount can vary for the various compounds/mixtures/compositions used in the invention. A pesticidally effective amount of the compositions will also vary according to the prevailing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, and the like.
- In the case of soil treatment, in furrow application or of application to the pests dwelling place or nest, the quantity of active ingredient ranges from 0.0001 to 500 g per 100 m2, preferably from 0.001 to 20 g per 100 m2.
- For use in treating crop plants, e.g. by foliar application, the rate of application of the active ingredients of this invention may be in the range of 0.0001 g to 4000 g per hectare, e.g. from 1 g to 2 kg per hectare or from 1 g to 750 g per hectare, desirably from 1 g to 100 g per hectare, more desirably from 10 g to 50 g per hectare, e.g., 10 to 20 g per hectare, 20 to 30 g per hectare, 30 to 40 g per hectare, or 40 to 50 g per hectare.
- The compounds I, preferably compound i) of formula (I), are particularly suitable for use in the treatment of seeds in order to protect the seeds from insect pests, in particular from soil-living insect pests, and the resulting seedling's roots and shoots against soil pests and foliar insects. The present invention therefore also relates to a method for the protection of seeds from insects, in particular from soil insects, and of the seedling's roots and shoots from insects, in particular from soil and foliar insects, said method comprising treating the seeds before sowing and/or after pregermination with the compound I, preferably compound i) of formula (I). The protection of the seedling's roots and shoots is preferred. More preferred is the protection of seedling's shoots from piercing and sucking insects, chewing insects and nematodes.
- The term “seed treatment” comprises all suitable seed treatment techniques known in the art, such as seed dressing, seed coating, seed dusting, seed soaking, seed pelleting, and in-furrow application methods. Preferably, the seed treatment application of the compound I, preferably compound i) of formula (I), is carried out by spraying or by dusting the seeds before sowing of the plants and before emergence of the plants.
- The present invention also comprises seeds coated with or containing the active compound I, preferably compound i) of formula (I). The term “coated with and/or containing” generally signifies that the active ingredient is for the most part on the surface of the propagation product at the time of application, although a greater or lesser part of the ingredient may penetrate into the propagation product, depending on the method of application. When the said propagation product is (re)planted, it may absorb the active ingredient.
- Suitable seed is for example seed of cereals, root crops, oil crops, vegetables, spices, ornamentals, for example seed of durum and other wheat, barley, oats, rye, maize (fodder maize and sugar maize/sweet and field corn), soybeans, oil crops, crucifers, cotton, sunflowers, bananas, rice, oilseed rape, turnip rape, sugarbeet, fodder beet, eggplants, potatoes, grass, lawn, turf, fodder grass, tomatoes, leeks, pumpkin/squash, cabbage, iceberg lettuce, pepper, cucumbers, melons, Brassica species, melons, beans, peas, garlic, onions, carrots, tuberous plants such as potatoes, sugar cane, tobacco, grapes, petunias, geranium/pelargoniums, pansies and impatiens.
- In addition, the active compound I, preferably compound i) of formula (I), may also be used for the treatment of seeds from plants, which have been modified by mutagenisis or genetic engineering, and which e.g. tolerate the action of herbicides or fungicides or insecticides. Such modified plants are described herein in detail elsewhere.
- Preferences
- Application methods, which are of particular relevance in connection with the mixture of the invention are described in detail further below. Preferences of particular importance are provided in the following.
- In one aspect, the present invention relates to the use of the carboxamide compound i) of formula (I) for protecting a cultivated plant, cultivated plant propagation material, or its locus of growth, against the attack or infestation by pests.
- In another aspect, the present invention relates to the use of the carboxamide compound ii) of formula (Ia) for protecting a cultivated plant, cultivated plant propagation material, or its locus of growth, against the attack or infestation by pests.
- In still another aspect, the present invention relates to the use of mixtures comprising the carboxamide compounds i) and ii) for protecting a cultivated plant, cultivated plant propagation material, or its locus of growth, against the attack or infestation by pests.
- In another aspect, the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of the carboxamide compound compound i) of formula (I) to a cultivated plant, cultivated plant propagation material, or its locus of growth; the pests or their food supply, habitat or breeding grounds.
- In another aspect, the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of the carboxamide compound ii) of formula (Ia) to a cultivated plant, cultivated plant propagation material, or its locus of growth; the pests or their food supply, habitat or breeding grounds.
- In another aspect, the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of a mixture comprising the carboxamide compounds i) and ii) to a cultivated plant, cultivated plant propagation material, or its locus of growth; the pests or their food supply, habitat or breeding grounds.
- The application of the carboxamide compound I, preferably compound i) of formula (I) in connection with the above use or method includes both contact with the cultivated plant or cultivated plant propagation material and contact with its locus of growth. The term “locus of growth” is to be understood as the locus, where the plant is growing, in particular the soil or water, in which the plant is growing.
- Furthermore, the methods of the present invention relates in one embodiment to the application to the pests or their food supply, habitat or breeding grounds.
- In a preferred embodiment of the above use or method comprising the application of the carboxamide compound i) of formula (I), it is applied to the plants, in particular parts of the plants such as the foliage.
- In another embodiment of the above use or method comprising the application of the carboxamide compound ii) of formula (Ia), it is applied to the plants, in particular parts of the plants such as the foliage.
- In another embodiment of the above use or method comprising the application of a mixture comprising the carboxamide compounds i) and ii), it is applied to the plants, in particular parts of the plants such as the foliage.
- In a particularly preferred embodiment of the above use or method, the carboxamide compound i) of formula (I) is applied to the foliage of the plants, preferably in an amount of from 1 g to 100 g per hectare, more preferably in an amount of from 10 g to 50 g per hectare.
- In another embodiment of the above use or method, the carboxamide compound ii) of formula (Ia) is applied to the foliage of the plants, preferably in an amount of from 1 g to 100 g per hectare, more preferably in an amount of from 10 g to 50 g per hectare.
- In still another embodiment of the above use or method, the mixture comprising the carboxamide compounds i) and ii) is applied to the foliage of the plants, preferably in an amount of from 1 g to 100 g per hectare, more preferably in an amount of from 10 g to 50 g per hectare.
- In an alternative preferred embodiment of the above use or method, the carboxamide compound i) of formula (I) is applied to the plant propagation material, preferably the seeds of a plant.
- In another embodiment of the above use or method, the carboxamide compound ii) of formula (Ia) is applied to the plant propagation material, preferably the seeds of a plant.
- In another embodiment of the above use or method, the mixture comprising the carboxamide compounds i) and ii) is applied to the plant propagation material, preferably the seeds of a plant.
- In a particularly preferred embodiment of the above use or method, the carboxamide compound i) of formula (I) is applied to the seeds of the plants, preferably in an amount of from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed.
- In another embodiment of the above use or method, the carboxamide compound ii) of formula (Ia) is applied to the seeds of the plants, preferably in an amount of from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed.
- In still another embodiment of the above use or method, the mixture comprising the carboxamide compounds i) and ii) is applied to the seeds of the plants, preferably in an amount of from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed.
- In case the carboxamide compound I, preferably compound i) of formula (I) is applied in a mixture with another agriculturally active ingredient, the components of the mixture can be as mentioned above—applied simultaneously, jointly or separately, or in succession, that is immediately one after another and thereby creating the mixture “in situ” on the desired location, e.g. the plant, the sequence, in the case of separate application, generally not having any effect on the result of the control measures.
- The application methods, uses and mixtures of the present invention are particularly useful for controlling insects of the orders Lepidoptera, Coleoptera and Thysanoptera.
- The application methods, uses and mixtures of the present invention are especially suitable for efficiently combating pests like insects from the order of the lepidopterans (Lepidoptera), beetles (Coleoptera) and thrips (Thysanoptera).
- In a preferred embodiment of the above use or method comprising the application of the mixture of the invention, the pests are selected from insects from the order of Lepidoptera, preferably from the group consisting of Anticarsia (=Thermesia) spp., Chrysodeixis (=Pseudoplusia) spp., Helicoverpa spp., Spodoptera (=Lamphygma) spp., and combinations thereof, more preferably from the group consisting of Helicoverpa spp., Spodoptera spp., and combinations thereof, most preferably from Helicoverpa armigera (=Heliothis armigera), Spodoptera spp., and combinations thereof, in particular from Helicoverpa armigera (=Heliothis armigera), Spodoptera frugiperda, Spodoptera cosmioides, and combinations thereof.
- In another preferred embodiment, the pests are selected from the group consisting of Anticarsia gemmatalis, Chlysodeixis includens (=Pseudoplusia includens), Helicoverpa armigera (=Heliothis armigera), Spodoptera frugiperda, Spodoptera eridania, Spodoptera cosmioides, and combinations thereof, and are preferably selected from Spodoptera eridania, Spodoptera cosmioides, or a combination thereof, and are particularly preferably Spodoptera cosmioides.
- In another preferred embodiment, the pests are Anticarsia gemmatalis.
- In another preferred embodiment, the pests are Chrysodeixis includens (=Pseudoplusiaincludens).
- In another preferred embodiment, the pests are Helicoverpa armigera (=Heliothis armigera).
- In another preferred embodiment, the pests are Spodoptera frugiperda.
- In another preferred embodiment, the pests are Spodoptera eridania.
- In another preferred embodiment, the pests are Spodoptera cosmioides.
- As outlined above, the above mentioned pests are of particular importance in connection with certain plants.
- In one embodiment of the above use or method comprising the application of the carboxamide compound i) of formula (I), the plant is a plant, which has been modified by conventional breeding, i.e. a plant, which has not been modified by mutagenesis or genetic engineering.
- In another embodiment of the above use or method comprising the application of the carboxamide compound ii) of formula (Ia), the plant is a plant, which has been modified by conventional breeding, i.e. a plant, which has not been modified by mutagenesis or genetic engineering.
- In another embodiment of the above use or method comprising the application of a mixture comprising the carboxamide compounds i) and ii), the plant is a plant, which has been modified by conventional breeding, i.e. a plant, which has not been modified by mutagenesis or genetic engineering.
- Preferably, the plant, which has not been modified by mutagenesis or genetic engineering, is selected from the group consisting of wheat, maize, rice, soybean, and cotton, and is more preferably a soybean plant.
- In another embodiment of the above use or method comprising the application of the mixture of the invention, the plant is a plant, which has been modified by mutagenesis or genetic engineering, preferably by genetic engineering.
- In a more preferred embodiment of such the embodiment, in the plant, which has been modified by mutagenesis or genetic engineering, one or more genes have been mutagenized or integrated into the genetic material of the plant, which are selected from pat, epsps, cry1 Ab, bar, cry1 Fa2, cry1 Ac, cry34Ab1, cry35AB1, cry3A, cryF, cry1F, mcry3a, cry2Ab2, cry3Bb1, cry1A.105, dfr, barnase, vip3Aa20, barstar, als, bxn, bp40, asn1, and ppo5.
- In another more preferred embodiment, the plant, which has been modified by mutagenesis or genetic engineering, exhibits one or more traits selected from the group consisting of abiotic stress tolerance, altered growth/yield, disease resistance, herbicide tolerance, insect resistance, modified product quality, and pollination control. Preferably, the plant exhibits herbicide tolerance, insect resistance or a combination thereof.
- In a preferred embodiment of the use or method as defined above, the plant is a plant, which has been modified by mutagenesis or genetic engineering, and which corresponds to any one of rows A1 to A385 of table A.
-
TABLE A Trait (Trait No. Crop, latin name Event Name Event Code Tradename type)/Gene Company A1 Alfalfa J101 MON-ØØ1Ø1-8 Roundup HT (Gly)/cp4 Monsanto Medicago sativa Ready ™ Alfalfa epsps (aroA:CP4) A2 Alfalfa J101 × J163 MON-ØØ1Ø1-8 × Roundup HT (Gly)/cp4 Monsanto Medicago sativa MON-ØØ163-7 Ready ™ Alfalfa epsps (aroA:CP4) HT (Gly)/cp4 epsps (aroA:CP4) A3 Alfalfa J163 MON-ØØ163-7 Roundup HT (Gly)/cp4 Monsanto Medicago sativa Ready ™ Alfalfa epsps (aroA:CP4) A4 Alfalfa KK179 MON-ØØ179-5 Not available ST (Lignin)/ccomt Monsanto Medicago sativa (inverted repeat) A5 Argentine Canola 23-18-17 CGN-89111-8 Laurical ™ ST (Oil)/te Monsanto Brassica napus (Event 18) Canola (thioesterase) A6 Argentine Canola 23-198 CGN-89465-2 Laurical ™ ST (Oil)/te Monsanto Brassica napus (Event 23) Canola (thioesterase) A7 Argentine Canola 61061 DP-Ø61Ø61-7 not available HT (Gly)/gat4621 Dupont Brassica napus A8 Argentine Canola 73496 DP-Ø73496-4 Optimum ® Gly HT (Gly)/gat4621 Dupont Brassica napus canola A9 Argentine Canola GT200 MON-89249-2 Roundup HT (Gly)/EPSPS Monsanto Brassica napus (RT200) Ready ™ Canola HT (Gly)/goxv247 A10 Argentine Canola GT73 MON-ØØØ73-7 Roundup HT (Gly)/EPSPS Monsanto Brassica napus (RT73) Ready ™ Canola HT (Gly)/goxv247 A11 Argentine Canola HCN10 not available Liberty Link ™ HT (Glu)/bar Bayer Crop Brassica napus (Topas 19/2) Independence ™ Science A12 Argentine Canola HCN28 ACS-BNØØ8-2 InVigor ™ Canola HT (Glu)/pat (syn) Bayer Crop Brassica napus (T45) Science A13 Argentine Canola HCN92 ACS-BNØØ7-1 Liberty Link ™ HT (Glu)/bar Bayer Crop Brassica napus (Topas 19/2) Innovator ™ Science A14 Argentine Canola MON88302 MON-883Ø2-9 TruFlex ™ HT (Gly)/cp4 Monsanto Brassica napus Roundup epsps (aroA:CP4) Ready ™ Canola A15 Argentine Canola MON88302 × MON-883Ø2-9 × not available HT (Gly)/cp4 Monsanto Brassica napus MS8 × RF3 ACS-BNØØ5-8 × epsps (aroA:CP4) ACS-BNØØ3-6 HT (Glu)/bar PC (MS)/barnase PC (FR)/barstar A16 Argentine Canola MON88302 × MON-883Ø2-9 × not available HT (Gly)/cp4 Monsanto Brassica napus RF3 ACS-BNØØ3-6 epsps (aroA:CP4) HT (Glu)/bar PC (FR)/barstar A17 Argentine Canola MPS961 not available Phytaseed ™ ST (P)/phyA BASF Brassica napus Canola A18 Argentine Canola MPS962 not available Phytaseed ™ ST (P)/phyA BASF Brassica napus Canola A19 Argentine Canola MPS963 not available Phytaseed ™ ST (P)/phyA BASF Brassica napus Canola A20 Argentine Canola MPS964 not available Phytaseed ™ ST (P)/phyA BASF Brassica napus Canola A21 Argentine Canola MPS965 not available Phytaseed ™ ST (P)/phyA BASF Brassica napus Canola A22 Argentine Canola MS1 (B91-4) ACS-BNØØ4-7 InVigor ™ Canola HT (Glu)/bar Bayer Crop Brassica napus PC (MS)/barnase Science A23 Argentine Canola MS1 × RF1 ACS-BNØØ4-7 × InVigor ™ Canola HT (Glu)/bar Bayer Crop Brassica napus (PGS1) ACS-BNØØ1-4 PC (MS)/barnase Science PC (FR)/barstar A24 Argentine Canola MS1 × RF2 ACS-BNØØ4-7 × InVigor ™ Canola HT (Glu)/bar Bayer Crop Brassica napus (PGS2) ACS-BNØØ2-5 PC (MS)/barnase Science PC (FR)/barstar A25 Argentine Canola MS1 × RF3 ACS-BNØØ4-7 × Invigor ™ Canola HT (Glu)/bar Bayer Crop Brassica napus ACS-BNØØ3-6 PC (MS)/barnase Science PC (FR)/barstar A26 Argentine Canola MS8 ACS-BNØØ5-8 InVigor ™ Canola HT (Glu)/bar Bayer Crop Brassica napus PC (MS)/barnase Science A27 Argentine Canola MS8 × RF3 ACS-BNØØ5-8 × InVigor ™ Canola HT (Glu)/bar Bayer Crop Brassica napus ACS-BNØØ3-6 PC (MS)/barnase Science PC (FR)/barstar A28 Argentine Canola MS8 × RF3 × ACS-BNØØ5-8 × not available HT (Glu)/bar Bayer Crop Brassica napus GT73 (RT73) ACS-BNØØ3-6 × PC (MS)/barnase Science MON-ØØØ73-7 PC (FR)/barstar HT (Gly)/EPSPS HT (Gly)/goxv247 A29 Argentine Canola OXY-235 ACS-BNØ11-5 Navigator ™ HT (Ox)/bxn Bayer Crop Brassica napus Canola Science A30 Argentine Canola PHY14 not available not available HT (Glu)/bar Bayer Crop Brassica napus PC (MS)/barnase Science PC (FR)/barstar A31 Argentine Canola PHY23 not available not available HT (Glu)/bar Bayer Crop Brassica napus PC (MS)/barnase Science PC (FR)/barstar A32 Argentine Canola PHY35 not available not available HT (Glu)/bar Bayer Crop Brassica napus PC (MS)/barnase Science PC (FR)/barstar A33 Argentine Canola PHY36 not available not available HT (Glu)/bar Bayer Crop Brassica napus PC (MS)/barnase Science PC (FR)/barstar A34 Argentine Canola RF1 (B93- ACS-BNØØ1-4 InVigor ™ Canola HT (Glu)/bar Bayer Crop Brassica napus 101) PC (FR)/barstar Science A35 Argentine Canola RF2 (B94-2) ACS-BNØØ2-5 InVigor ™ Canola HT (Glu)/bar Bayer Crop Brassica napus PC (FR)/barstar Science A36 Argentine Canola RF3 ACS-BNØØ3-6 InVigor ™ Canola HT (Glu)/bar Bayer Crop Brassica napus PC (FR)/barstar Science A37 Argentine Canola 45A37, 45A37, 46A40 not available ST (Oil)/fad2 Pioneer Brassica napus 46A40 (mutant) A38 Argentine Canola 46A12, 46A12, 46A16 not available ST (Oil)/fad2 Pioneer Brassica napus 46A16 (mutant) A39 Argentine Canola NS738, NS738, NS1471, Clearfield Canola HT (Imi)/als Pioneer Brassica napus NS1471, NS1473 (mutant) NS1473 A40 Bean EMB6X 5.1 EMB-PVØ51-1 not available VR (BGMV)/ac1 Embrapa Phaseolus vulgaris (sense and anti- sense) A41 Carnation 11 (7442) FLO-Ø7442-4 Moondust ™ ST (Color)/dfr Florigene Dianthus caryophyllus ST (Color)/hfl Pty. Ltd. (f3′5′h) A42 Carnation 11363 FLO-11363-1 Moonshadow ™ ST (Color)/dfr Florigene Dianthus caryophyllus (1363A) ST (Color)/bp40 Pty. Ltd. (f3′5′h) A43 Carnation 1226A FLO-11226-8 Moonshade ™ ST (Color)/dfr Florigene Dianthus caryophyllus (11226) ST (Color)/bp40 Pty. Ltd. (f3′5′h) A44 Carnation 123.2.2 FLO-4Ø619-7 Moonshade ™ ST (Color)/dfr Florigene Dianthus caryophyllus (40619) ST (Color)/hfl Pty. Ltd. (f3′5′h) A45 Carnation 123.2.38 FLO-4Ø644-4 Moonlite ™ ST (Color)/dfr Florigene Dianthus caryophyllus (40644) ST (Color)/hfl Pty. Ltd. (f3′5′h) A46 Carnation 123.8.12 FLO-4Ø689-6 Moonaqua ™ ST (Color)/dfr Florigene Dianthus caryophyllus ST (Color)/bp40 Pty. Ltd. (f3′5′h) A47 Carnation 123.8.8 FLO-4Ø685-1 Moonvista ™ ST (Color)/dfr Florigene Dianthus caryophyllus (40685) ST (Color)/bp40 Pty. Ltd. (f3′5′h) A48 Carnation 1351A FLO-11351-7 Moonshade ™ ST (Color)/dfr Florigene Dianthus caryophyllus (11351) ST (Color)/bp40 Pty. Ltd. (f3′5′h) A49 Carnation 1400A FLO-114ØØ-2 Moonshade ™ ST (Color)/dfr Florigene Dianthus caryophyllus (11400) ST (Color)/bp40 Pty. Ltd. (f3′5′h) A50 Carnation 15 FLO-ØØØ15-2 Moondust ™ ST (Color)/dfr Florigene Dianthus caryophyllus ST (Color)/hfl Pty. Ltd. (f3′5′h) A51 Carnation 16 FLO-ØØØ16-3 Moondust ™ ST (Color)/dfr Florigene Dianthus caryophyllus ST (Color)/hfl Pty. Ltd. (f3′5′h) A52 Carnation 199Ø7 IFD-199Ø7-9 Moonique ™ ST (Color)/dfr Suntory Ltd. Dianthus caryophyllus ST (Color)/bp40 (f3′5′h) ST (Color)/sfl (f3′5′h) HT (SU)/surB A53 Carnation 25947 IFD-25947-1 Moonpearl ™ ST (Color)/bp40 Suntory Ltd. Dianthus caryophyllus (f3′5′h) ST (Color)/dfr ST (Color)/dfr-diaca HT (SU)/surB A54 Carnation 25958 IFD-25958-3 Moonberry ™ ST (Color)/bp40 Suntory Ltd. Dianthus caryophyllus (f3′5′h) ST (Color)/dfr ST (Color)/dfr-diaca HT (SU)/surB A55 Carnation 264Ø7 IFD-264Ø7-2 Moonvelvet ™ ST (Color)/hfl Suntory Ltd. Dianthus caryophyllus (f3′5′h) ST (Color)/cytb5 HT (SU)/surB A56 Carnation 4 FLO-ØØØØ4-9 Moondust ™ ST (Color)/dfr Florigene Dianthus caryophyllus ST (Color)/hfl Pty. Ltd. (f3′5′h) A57 Carnation 66 FLO-ØØØ66-8 not available ST (Ripe)/acc Florigene Dianthus caryophyllus (truncated) Pty. Ltd. A58 Carnation 959A FLO-11959-3 Moonshade ™ ST (Color)/dfr Florigene Dianthus caryophyllus (11959) ST (Color)/bp40 Pty. Ltd. (f3′5′h) A59 Carnation 988A FLO-11988-7 Moonshade ™ ST (Color)/dfr Florigene Dianthus caryophyllus (11988) ST (Color)/bp40 Pty. Ltd. (f3′5′h) A60 Chicory RM3-3 not available Seed Link ™ HT (Glu)/bar Bejo Zaden Cichorium intybus PC (MS)/barnase BV A61 Chicory RM3-4 not available Seed Link ™ HT (Glu)/bar Bejo Zaden Cichorium intybus PC (MS)/barnase BV A62 Chicory RM3-6 not available Seed Link ™ HT (Glu)/bar Bejo Zaden Cichorium intybus PC (MS)/barnase BV A63 Cotton 19-51a DD-Ø1951A-7 not available HT (SU)/S4-hrA Dupont Gossypium hirsutum A64 Cotton 281-24-236 DAS-24236-5 not available IR (BL)/cry1F Dow Gossypium hirsutum A65 Cotton 281-24-236 × DAS-24236-5 × WideStrike ™ IR (BL)/cry1F Dow Gossypium hirsutum 3006-210-23 DAS-21Ø23-5 Cotton IR (BL)/cry1Ac (MXB-13) A66 Cotton 3006-210-23 DAS-21Ø23-5 not available IR (BL)/Cry1Ac Dow Gossypium hirsutum A67 Cotton 3006-210-23 × DAS-21Ø23-5 × WideStrike ™ HT (Gly)/cp4 Monsanto Gossypium hirsutum 281-24-236 × DAS-24236-5 × Roundup epsps (aroA:CP4) MON1445 MON-Ø1445-2 Ready ™ Cotton IR (BL)/cry1F IR (BL)/cry1Ac HT (Glu)/bar A68 Cotton 3006-210-23 × DAS-21Ø23-5 × Widestrike ™ HT (Gly)/cp4 Dow & Gossypium hirsutum 281-24-236 × DAS-24236-5 × Roundup Ready epsps (aroA:CP4) Monsanto MON88913 MON-88913-8 Flex ™ Cotton IR (BL)/cry1F IR (BL)/cry1Ac HT (Glu)/bar A69 Cotton 3006-210-23 × DAS-21Ø23-5 × Widestrike ™ × IR (BL)/cry1Ac Dow Gossypium hirsutum 281-24-236 × DAS-24236-5 × Roundup Ready IR (BL)/vip3A(a) MON88913 × MON-88913-8 × Flex ™ × VIP- IR (BL)/cry1F COT102 SYN-IR1Ø2-7 COT ™ Cotton HT (Gly)/cp4 epsps (aroA:CP4) HT (Glu)/pat A70 Cotton 31707 not available BXN ™ Plus HT (Ox)/bxn Monsanto Gossypium hirsutum Bollgard ™ IR (BL)/cry1Ac Cotton A71 Cotton 31803 not available BXN ™ Plus HT (Ox)/bxn Monsanto Gossypium hirsutum Bollgard ™ IR (BL)/cry1Ac Cotton A72 Cotton 31807 × 31808 not available not available 2HT (Ox)/bxn Monsanto Gossypium hirsutum 2IR (BL)/cry1Ac / / A73 Cotton 31807 not available BXN ™ Plus HT (Ox)/bxn Monsanto Gossypium hirsutum Bollgard ™ IR (BL)/cry1Ac Cotton A74 Cotton 31808 not available BXN ™ Plus HT (Ox)/bxn Monsanto Gossypium hirsutum Bollgard ™ IR (BL)/cry1Ac Cotton A75 Cotton 42317 not available BXN ™ Plus HT (Ox)/bxn Monsanto Gossypium hirsutum Bollgard ™ IR (BL)/cry1Ac Cotton A76 Cotton BNLA-601 not available not available IR (BL)/cry1Ac Central Insti- Gossypium hirsutum tute for Cotton Research and University of Agricultural Sciences Dharwad (India) A77 Cotton BXN10211 BXN-1Ø211-9 BXN ™ Cotton HT (Ox)/bxn Monsanto Gossypium hirsutum (10211) A78 Cotton BXN10215 BXN-1Ø215-4 BXN ™ Cotton HT (Ox)/bxn Monsanto Gossypium hirsutum (10215) A79 Cotton BXN10222 BXN-1Ø222-2 BXN ™ Cotton HT (Ox)/bxn Monsanto Gossypium hirsutum (10222) A80 Cotton BXN10224 BXN-1Ø224-4 BXN ™ Cotton HT (Ox)/bxn Monsanto Gossypium hirsutum (10224) A81 Cotton COT102 SYN-IR1Ø2-7 VIPCOT ™ IR (BL)/vip3A(a) Syngenta Gossypium hirsutum (IR102) Cotton A82 Cotton COT102 × SYN-IR1Ø2-7 × VIPCOT ™ IR (BL)/vip3A(a) Syngenta Gossypium hirsutum COT67B SYN-IR67B-1 Cotton IR (BL)/cry1Ab A83 Cotton COT102 × SYN-IR1Ø2-7 × VIPCOT ™ IR (BL)/vip3A(a) Syngenta Gossypium hirsutum COT67B × SYN-IR67B-1 × Roundup Ready IR (BL)/cry1Ab MON88913 MON-88913-8 Flex ™ Cotton A84 Cotton COT102 × SYN-IR1Ø2-7 × Bollgard ® III IR (BL)/vip3A(a) Monsanto Gossypium hirsutum MON15985 MON-15985-7 IR (BL)/cry1Ac IR (BL)/cry2Ab2 A85 Cotton COT102 × SYN-IR1Ø2-7 × Bollgard ® III × IR (BL)/vip3A(a) Monsanto Gossypium hirsutum MON15985 × MON-15985-7 × Roundup IR (BL)/cry1Ac MON88913 MON-88913-8 Ready ™ Flex ™ IR (BL)/cry2Ab2 HT (Gly)/cp4 epsps (aroA:CP4) A86 Cotton COT67B SYN-IR67B-1 not available IR (BL)/cry1Ab Syngenta Gossypium hirsutum (IR67B) A87 Cotton Event1 not available JK 1 IR (BL)/cry1Ac JK Agri Ge- Gossypium hirsutum netics Ltd. (India) A88 Cotton GFM Cry1A GTL-GFM311-7 not available IR (BL)/cry1Ab-Ac Nath Gossypium hirsutum Seeds/Global Transgenes Ltd (India) A89 Cotton GHB119 BCS-GHØØ5-8 not available HT (Glu)/bar Bayer Crop Gossypium hirsutum IR (BL)/cry2Ae Science A90 Cotton GHB614 BCS-GHØØ2-5 GlyTol ™ HT (Gly)/2mepsps Bayer Crop Gossypium hirsutum Science A91 Cotton GHB614 × BCS-GHØØ2-5 × GlyTol ™ Liberty HT (Gly)/2mepsps Bayer Crop Gossypium hirsutum LLCotton25 ACS-GHØØ1-3 Link ™ HT (Glu)/bar Science A92 Cotton GHB614 × BCS-GHØØ2-5 × not available HT (Gly)/2mepsps Bayer Crop Gossypium hirsutum LLCotton25 × ACS-GHØØ1-3 × HT (Glu)/bar Science MON15985 MON-15985-7 IR (BL)/cry1Ac IR (BL)/cry2Ab2 A93 Cotton GHB614 × BCS-GHØØ2-5 × not available HT (Gly)/2mepsps Bayer Crop Gossypium hirsutum MON15985 MON-15985-7 IR (BL)/cry1Ac Science IR (BL)/cry2Ab2 A94 Cotton GHB614 × BCS-GHØØ2-5 × Glytol ™ × HT (Gly)/2mepsps Bayer Crop Gossypium hirsutum T304-40 × BCS-GHØØ4-7 × Twinlink ™ HT (Glu)/bar Science GHB119 BCS-GHØØ5-8 IR (BL)/cry1Ab IR (BL)/cry2Ae A95 Cotton GK12 not available not available IR (BL)/cry1Ab-Ac Chinese Gossypium hirsutum Academy of Agricultural Sciences A96 Cotton LLCotton25 ACS-GHØØ1-3 Fibermax ™ HT (Glu)/bar Bayer Crop Gossypium hirsutum Liberty Link ™ Science A97 Cotton LLCotton25 × ACS-GHØØ1-3 × Fibermax ™ HT (Glu)/bar Gossypium hirsutum MON15985 MON-15985-7 Liberty Link ™ IR (BL)/cry1Ac Bollgard II ™ IR (BL)/cry2Ab2 A98 Cotton MLS 9124 not available not available IR (BL)/cry1C Metahelix Gossypium hirsutum Life Sciences Pvt. Ltd (India) A99 Cotton MON 887Ø1-3 MON88701 not available HT (Dic)/dmo Monsanto Gossypium hirsutum HT (Glu)/bar A100 Cotton MON1076 MON-89924-2 Bollgard ™ IR (BL)/cry1Ac Monsanto Gossypium hirsutum Cotton A101 Cotton MON1445 MON-Ø1445-2 Roundup HT (Gly)/cp4 Monsanto Gossypium hirsutum Ready ™ Cotton epsps (aroA:CP4) A102 Cotton MON15985 MON-15985-7 Bollgard II ™ IR (BL)/cry1Ac Monsanto Gossypium hirsutum Cotton IR (BL)/cry2Ab2 A103 Cotton MON15985 × MON-15985-7 × Roundup Ready ™ HT (Gly)/cp4 Monsanto Gossypium hirsutum MON1445 MON-Ø1445-2 Bollgard II ™ epsps (aroA:CP4) Cotton IR (BL)/cry1Ac IR (BL)/cry2Ab2 A104 Cotton MON1698 MON-89383-1 Roundup Ready ™ HT (Gly)/cp4 Monsanto Gossypium hirsutum Cotton epsps (aroA:CP4) A105 Cotton MON531 MON-ØØ531-6 Bollgard ™ IR (BL)/cry1Ac Monsanto Gossypium hirsutum Cotton, Ingard ™ A106 Cotton MON531 × MON-Ø531-6 × Roundup Ready ™ HT (Gly)/cp4 Monsanto Gossypium hirsutum MON1445 MON-Ø1445-2 Bollgard ™ epsps (aroA:CP4) Cotton IR (BL)/cry1Ac A107 Cotton MON757 MON-ØØ757-7 Bollgard ™ IR (BL)/cry1Ac Monsanto Gossypium hirsutum Cotton A108 Cotton MON88913 MON-88913-8 Roundup Ready ™ HT (Gly)/cp4 Monsanto Gossypium hirsutum Flex ™ epsps (aroA:CP4) Cotton A109 Cotton MON88913 × MON-88913-8 × Roundup Ready ™ HT (Gly)/cp4 Monsanto Gossypium hirsutum MON15985 MON-15985-7 Flex ™ epsps (aroA:CP4) Bollgard II ™ IR (BL)/cry1Ac Cotton IR (BL)/cry2Ab2 A110 Cotton Ngwe Chi 6 not available Ngwe Chi 6 Bt Cotton and Gossypium hirsutum Bt Sericulture Department (Myanmar) A111 Cotton SGK321 not available not available IR (BL)/cry1A Chinese Gossypium hirsutum IR (BRun)/CpTI Academy of Agricultural Sciences A112 Cotton T303-3 BCS-GHØØ3-6 not available IR (BL)/cry1Ab Bayer Crop Gossypium hirsutum HT (Glu)/bar Science A113 Cotton T304-40 BCS-GHØØ4-7 not available IR (BL)/cry1Ab Bayer Crop Gossypium hirsutum HT (Glu)/bar Science A114 Cotton T304-40 × BCS-GHØØ4-7 × TwinLink ™ IR (BL)/cry1Ab Bayer Crop Gossypium hirsutum GHB119 BCS-GHØØ5-8 Cotton HT (Glu)/bar Science A115 Cotton 81910 DAS-81910-7 not available HT (2,4-D)/aad-12 Dow Gossypium hirsutum HT (Glu)/pat A116 Creeping Bentgrass ASR368 SMG-368ØØ-2 Roundup Ready ™ HT (Gly)/cp4 Monsanto Agrostis stolonifera Creeping Bentgrass epsps (aroA:CP4) A117 Eggplant Bt Brinjal Bt Brinjal Event EE1 BARI Bt Begun- IR (BL)/cry1Ac Maharashtra Solanum melongena Event EE1 1, -2, -3 and -4 Hybrid Seed Company (MAHYCO) A118 Flax FP967 (CDC CDC-FLØØ1-2 CDC Triffid Flax HT (SU)/als University of Linum usitatissimum Triffid) Saskatchewan A119 Lentil RH44 RH44 not available HT (Imi)/als BASF Lens culinaris (mutant) A120 Maize 32138 DP-32138-1 32138 SPT PC (FR)/ms45 Dupont Zea mays maintainer PC (MS)/zm-aa1 A121 Maize 3272 SYN-E3272-5 Enogen ™ ST (CA)/amy797E Syngenta Zea mays A122 Maize 3272 × Bt11 SYN-E3272-5 × not available ST (CA)/amy797E Syngenta Zea mays SYN-BTØ11-1 IR (BL)/cry1Ab HT (Glu)/pat A123 Maize 3272 × Bt11 × SYN-E3272-5 × not available ST (CA)/amy797E Syngenta Zea mays GA21 SYN-BTØ11-1 × IR (BL)/cry1Ab MON-ØØØ21-9 HT (Glu)/pat HT (Gly)/mepsps A124 Maize 3272 × Bt11 × SYN-E3272-5 × not available ST (CA)/amy797E Syngenta Zea mays MIR604 SYN-BTØ11-1 × IR (BL)/cry1Ab SYN-IR6Ø4-5 HT (Glu)/pat IR (Col)/mcry3A A125 Maize 3272 × BT11 × SYN-E3272-5 × not available ST (CA)/amy797E Syngenta Zea mays MIR604 × GA21 SYN-BTØ11-1 × IR (BL)/cry1Ab SYN-IR6Ø4-5 × HT (Glu)/pat MON-ØØØ21-9 IR (Col)/mcry3A HT (Gly)/mepsps A126 Maize 3272 × GA21 SYN-E3272-5 × not available ST (CA)/amy797E Syngenta Zea mays MON-ØØØ21-9 HT (Gly)/mepsps A127 Maize 3272 × SYN-E3272-5 × not available ST (CA)/amy797E Syngenta Zea mays MIR604 SYN-IR6Ø4-5 IR (Col)/mcry3A A128 Maize 3272 × SYN-E3272-5 × not available ST (CA)/amy797E Syngenta Zea mays MIR604 × SYN-IR6Ø4-5 × IR (Col)/mcry3A GA21 MON-ØØØ21-9 HT (Gly)/mepsps A129 Maize 33121 DP-Ø33121-3 not available IR (BL)/cry2Ae Dupont Zea mays IR (BL)/cry1A IR (BL)/vip3Aa20 HT (Glu)/pat A130 Maize 4114 DP-ØØ4114-3 not available IR (BL)/cry1F Dupont Zea mays IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 HT (Glu)/pat A131 Maize 5307 SYN-Ø53Ø7-1 Agrisure ® IR (Col)/ecry3.1Ab Syngenta Zea mays Duracade ™ A132 Maize 5307 × SYN-Ø53Ø7-1 × Agrisure ® IR (Col)/ecry3.1Ab Syngenta Zea mays MIR604 × SYN-IR6Ø4-5 × Duracade ™ IR (Col)/mcry3A Bt11 × SYN-BTØ11-1 × 5122 IR (BL)/cry1Ab TC1507 × DAS-Ø15Ø7-1 × HT (Glu)/pat GA21 MON-ØØØ21-9 IR (BL)/cry1Fa2 HT (Gly)/mepsps A133 Maize 5307 × SYN-Ø53Ø7-1 × Agrisure ® IR (Col)/ecry3.1Ab Syngenta Zea mays MIR604 × SYN-IR6Ø4-5 × Duracade ™ IR (Col)/mcry3A Bt11 × SYN-BTØ11-1 × 5222 IR (BL)/cry1Ab TC1507 × DAS-Ø15Ø7-1 × HT (Glu)/pat GA21 × MON-ØØØ21-9 × IR (BL)/cry1Fa2 MIR162 SYN-IR162-4 HT (Gly)/mepsps IR (BL)/vip3Aa20 A134 Maize 59122 DAS-59122-7 Herculex ™ RW HT (Glu)/pat Dow Zea mays IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 A135 Maize 59122 × DAS-59122-7 × not available HT (Glu)/pat Syngenta Zea mays GA21 MON-ØØØ21-9 IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 HT (Gly)/mepsps A136 Maize 59122 × DAS-59122-7 × not available HT (Glu)/pat Syngenta Zea mays MIR604 SYN-IR6Ø4-5 IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 IR (Col)/mcry3A A137 Maize 59122 × DAS-59122-7 × not available HT (Glu)/pat Syngenta Zea mays MIR604 × SYN-IR6Ø4-5 × IR (Col)/cry34Ab1 GA21 MON-ØØØ21-9 IR (Col)/cry35Ab1 IR (Col)/mcry3A HT (Gly)/mepsps A138 Maize 59122 × DAS-59122-7 × not available HT (Glu)/pat Syngenta Zea mays MIR604 × SYN-IR6Ø4-5 × IR (Col)/cry34Ab1 TC1507 DAS-Ø15Ø7-1 IR (Col)/cry35Ab1 IR (Col)/mcry3A IR (BL)/cry1Fa2 A139 Maize 59122 × DAS-59122-7 × not available HT (Glu)/pat Syngenta Zea mays MIR604 × SYN-IR6Ø4-5 × IR (Col)/cry34Ab1 TC1507 × DAS-Ø15Ø7-1 × IR (Col)/cry35Ab1 GA21 MON-ØØØ21-9 IR (Col)/mcry3A IR (BL)/cry1Fa2 HT (Gly)/mepsps A140 Maize 59122 × DAS-59122-7 × not available HT (Glu)/pat Dupont Zea mays MON810 MON-ØØ81Ø-6 IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 IR (BL)/cry1Ab A141 Maize 59122 × DAS-59122-7 × not available HT (Glu)/pat Dupont Zea mays MON810 × MON-ØØ81Ø-6 × IR (Col)/cry34Ab1 NK603 MON-ØØ6Ø3-6 IR (Col)/cry35Ab1 IR (BL)/cry1Ab HT (Gly)/cp4 epsps (aroA:CP4) A142 Maize 59122 × DAS-59122-7 × not available HT (Glu)/pat Monsanto & Zea mays MON88017 MON-88Ø17-3 IR (Col)/cry34Ab1 Dow IR (Col)/cry35Ab1 IR (Col)/cry3Bb1 HT (Gly)/cp4 epsps (aroA:CP4) A143 Maize 59122 × DAS-59122-7 × Herculex ™ RW HT (Glu)/pat Dupont Zea mays NK603 MON-ØØ6Ø3-6 Roundup Ready ™ 2 IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 HT (Gly)/cp4 epsps (aroA:CP4) A144 Maize 59122 × DAS-59122-7 × not available HT (Glu)/pat Syngenta Zea mays TC1507 × DAS-Ø15Ø7-1 × IR (Col)/cry34Ab1 GA21 MON-ØØØ21-9 IR (Col)/cry35Ab1 IR (BL)/cry1Fa2 HT (Gly)/mepsps A145 Maize 676 PH-ØØØ676-7 not available HT (Glu)/pat Dupont Zea mays PC (MS)/dam A146 Maize 678 PH-ØØØ678-9 not available HT (Glu)/pat Dupont Zea mays PC (MS)/dam A147 Maize 680 PH-ØØØ68Ø-2 not available HT (Glu)/pat Dupont Zea mays PC (MS)/dam A148 Maize 98140 DP-Ø9814Ø-6 Optimum ™ HT (SU)/zm-hra Dupont Zea mays GAT ™ HT (Gly)/gat4621 A149 Maize 98140 × DP-Ø9814Ø-6 × not available HT (Glu)/pat Dow & Zea mays 59122 DAS-59122-7 IR (Col)/cry34Ab1 Dupont IR (Col)/cry35Ab1 HT (SU)/zm-hra HT (Gly)/gat4621 A150 Maize 98140 × DP-Ø9814Ø-6 × not available HT (SU)/zm-hra Dow & Zea mays TC1507 DAS-Ø15Ø7-1 HT (Gly)/gat4621 Dupont IR (BL)/cry1Fa2 HT (Glu)/pat A151 Maize 98140 × DP-Ø9814Ø-6 × not available HT (Glu)/pat Dow & Zea mays TC1507 × DAS-Ø15Ø7-1 × IR (Col)/cry34Ab1 Dupont 59122 DAS-59122-7 IR (Col)/cry35Ab1 HT (SU)/zm-hra HT (Gly)/gat4621 IR (BL)/cry1Fa2 A152 Maize Bt10 not available Bt10 IR (BL)/cry1Ab Syngenta Zea mays HT (Glu)/pat A153 Maize Bt11 SYN-BTØ11-1 Agrisure ™ IR (BL)/cry1Ab Syngenta Zea mays (X4334CBR, CB/LL HT (Glu)/pat X4734CBR) A154 Maize Bt11 × SYN-BTØ11-1 × not available HT (Glu)/pat Syngenta Zea mays 59122 DAS-59122-7 IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 IR (BL)/cry1Ab A155 Maize Bt11 × SYN-BTØ11-1 × not available HT (Glu)/pat Syngenta Zea mays 59122 × DAS-59122-7 × IR (Col)/cry34Ab1 GA21 MON-ØØØ21-9 IR (Col)/cry35Ab1 IR (BL)/cry1Ab HT (Gly)/mepsps A156 Maize Bt11 × SYN-BTØ11-1 × not available HT (Glu)/pat Syngenta Zea mays 59122 × DAS-59122-7 × IR (Col)/cry34Ab1 MIR604 SYN-IR6Ø4-5 IR (Col)/cry35Ab1 IR (BL)/cry1Ab IR (Col)/mcry3a A157 Maize Bt11 × SYN-BTØ11-1 × not available HT (Glu)/pat Syngenta Zea mays 59122 × DAS-59122-7 × IR (Col)/cry34Ab1 MIR604 × SYN-IR6Ø4-5 × IR (Col)/cry35Ab1 GA21 MON-ØØØ21-9 IR (BL)/cry1Ab IR (Col)/mcry3a HT (Gly)/mepsps A158 Maize Bt11 × SYN-BTØ11-1 × not available HT (Glu)/pat Syngenta Zea mays 59122 × DAS-59122-7 × IR (Col)/cry34Ab1 MIR604 × SYN-IR6Ø4-5 × IR (Col)/cry35Ab1 TC1507 DAS-Ø15Ø7-1 IR (BL)/cry1Ab IR (BL)/cry1Fa2 IR (Col)/mcry3a A159 Maize BT11 × SYN-BTØ11-1 × Agrisure ® 3122 HT (Glu)/pat Syngenta Zea mays 59122 × DAS-59122-7 × IR (Col)/cry34Ab1 MIR604 × SYN-IR6Ø4-5 × IR (Col)/cry35Ab1 TC1507 × DAS-Ø15Ø7-1 × IR (BL)/cry1Ab GA21 MON-ØØØ21-9 IR (BL)/cry1Fa2 IR (Col)/mcry3a HT (Gly)/mepsps A160 Maize Bt11 × SYN-BTØ11-1 × not available HT (Glu)/pat Syngenta Zea mays 59122 × DAS-59122-7 × IR (Col)/cry34Ab1 TC1507 DAS-Ø15Ø7-1 IR (Col)/cry35Ab1 IR (BL)/cry1Ab IR (BL)/cry1Fa2 A161 Maize Bt11 × SYN-BTØ11-1 × not available HT (Glu)/pat Syngenta Zea mays 59122 × DAS-59122-7 × IR (Col)/cry34Ab1 TC1507 × DAS-Ø15Ø7-1 × IR (Col)/cry35Ab1 GA21 MON-ØØØ21-9 IR (BL)/cry1Ab IR (BL)/cry1Fa2 HT (Gly)/mepsps A162 Maize Bt11 × SYN-BTØ11-1 × Agrisure ™ HT (Gly)/mepsps Syngenta Zea mays GA21 MON-ØØØ21-9 GT/CB/LL IR (BL)/cry1Ab HT (Glu)/pat A163 Maize Bt11 × SYN-BTØ11-1 × Agrisure ® IR (BL)/cry1Ab Syngenta Zea mays MIR162 SYN-IR162-4 Viptera ™ 2100 (truncated) HT (Glu)/pat IR (BL)/vip3Aa20 A164 Maize Bt11 × SYN-BTØ11-1 × Agrisure ® IR (BL)/cry1Ab Syngenta Zea mays MIR162 × SYN-IR162-4 × Viptera ™ 3110 HT (Glu)/pat GA21 MON-ØØØ21-9 IR (BL)/vip3Aa20 HT (Gly)/mepsps A165 Maize BT11 × SYN-BTØ11-1 × Agrisure ® IR (BL)/cry1Ab Syngenta Zea mays MIR162 × SYN-IR162-4 × Viptera ™ 3100 HT (Glu)/pat MIR604 SYN-IR6Ø4-5 IR (BL)/vip3Aa20 IR (Col)/mcry3a A166 Maize Bt11 × SYN-BTØ11-1 × Agrisure ® IR (BL)/cry1Ab Syngenta Zea mays MIR162 × SYN-IR162-4 × Viptera ™ 3111, HT (Glu)/pat MIR604 × SYN-IR6Ø4-5 × Agrisure ® IR (BL)/vip3Aa20 GA21 MON-ØØØ21-9 Viptera ™ 4 IR (Col)/mcry3a HT (Gly)/mepsps A167 Maize Bt11 × SYN-BTØ11-1 × not available IR (BL)/cry1Ab Syngenta Zea mays MIR162 × SYN-IR162-4 × HT (Glu)/pat TC1507 DAS-Ø15Ø7-1 IR (BL)/vip3Aa20 IR (BL)/cry1Fa2 A168 Maize Bt11 × SYN-BTØ11-1 × Agrisure ™ IR (BL)/cry1Ab Syngenta Zea mays MIR162 × SYN-IR162-4 × Viptera 3220 HT (Glu)/pat TC1507 × DAS-Ø15Ø7-1 × IR (BL)/vip3Aa20 GA21 MON-ØØØ21-9 IR (BL)/cry1Fa2 HT (Gly)/mepsps A169 Maize Bt11 × SYN-BTØ11-1 × Agrisure ™ IR (BL)/cry1Ab Syngenta Zea mays MIR604 SYN-IR6Ø4-5 CB/LL/RW HT (Glu)/pat IR (Col)/mcry3a A170 Maize BT11 × SYN-BTØ11-1 × Agrisure ™ IR (BL)/cry1Ab Syngenta Zea mays MIR604 × SYN-IR6Ø4-5 × 3000GT HT (Glu)/pat GA21 MON-ØØØ21-9 IR (Col)/mcry3a HT (Gly)/mepsps A171 Maize Bt11 × SYN-BTØ11-1 × not available IR (BL)/cry1Ab Syngenta Zea mays MIR604 × SYN-IR6Ø4-5 × HT (Glu)/pat TC1507 DAS-Ø15Ø7-1 IR (Col)/mcry3a IR (BL)/cry1Fa2 A172 Maize Bt11 × SYN-BTØ11-1 × not available IR (BL)/cry1Ab Syngenta Zea mays TC1507 DAS-Ø15Ø7-1 HT (Glu)/pat IR (BL)/cry1Fa2 A173 Maize Bt11 × SYN-BTØ11-1 × not available IR (BL)/cry1Ab Syngenta Zea mays TC1507 × DAS-Ø15Ø7-1 × HT (Glu)/pat GA21 MON-ØØØ21-9 IR (BL)/cry1Fa2 HT (Gly)/mepsps A174 Maize Bt176 (176) SYN-EV176-9 NaturGard IR (BL)/cry1Ab Syngenta Zea mays KnockOut ™, HT (Glu)/bar Maximizer ™ A175 Maize BVLA430101 not available not available ST (P)/phyA2 Origin Zea mays Agritech (China) A176 Maize CBH-351 ACS-ZMØØ4-3 Starlink ™ Maize IR (BL)/cry9c Bayer Crop Zea mays HT (Glu)/bar Sciences A177 Maize DAS40278 DAS-4Ø278-9 Enlist ™ Maize HT (2,4-D)/aad1 Dow Zea mays A178 Maize DAS40278 × DAS-4Ø278-9 × not available HT (2,4-D)/aad1 Dow Zea mays NK603 MON-ØØ6Ø3-6 HT (Gly)/cp4 epsps (aroA:CP4) A179 Maize DBT418 DKB-89614-9 Bt Xtra ™ Maize IR (BL)/Cry1Ac Monsanto Zea mays IR (BL)/pinII HT (Glu)/bar A180 Maize DLL25 (B16) DKB-8979Ø-5 not available HT (Glu)/bar Monsanto Zea mays A181 Maize GA21 MON-ØØØ21-9 Roundup HT (Gly)/mepsps Monsanto Zea mays Ready ™ Maize, Agrisure ™ GT A182 Maize GA21 × MON-ØØØ21-9 × Roundup IR (BL)/cry1Ab Monsanto Zea mays MON810 MON-ØØ81Ø-6 Ready ™ HT (Gly)/mepsps YieldGard ™ maize A183 Maize GA21 × T25 MON-ØØØ21-9 × not available HT (Gly)/mepsps Syngenta Zea mays ACS-ZMØØ3-2 HT (Glu)/pat (syn) A184 Maize HCEM485 HCEM485 not available HT (Gly)/2mepsps Stine Seed Zea mays Farm, Inc (USA) A185 Maize LY038 REN-ØØØ38-3 Mavera ™ Maize ST (AA)/cordapA Renessen LLC Zea mays (Netherlands) A186 Maize LY038 × REN-ØØØ38-3 × Mavera ™ ST (AA)/cordapA Renessen LLC Zea mays MON810 MON-ØØ81Ø-6 YieldGard ™ IR (BL)/cry1Ab (Netherlands) Maize & Monsanto A187 Maize MIR162 SYN-IR162-4 Agrisure ™ IR (BL)/vip3Aa20 Syngenta Zea mays Viptera A188 Maize MIR162 × SYN-IR162-4 × not available IR (BL)/vip3Aa20 Syngenta Zea mays GA21 MON-ØØØ21-9 HT (Gly)/mepsps A189 Maize MIR162 × SYN-IR162-4 × not available IR (BL)/vip3Aa20 Syngenta Zea mays MIR604 SYN-IR6Ø4-5 IR (Col)/mcry3a A190 Maize MIR162 × SYN-IR162-4 × not available IR (BL)/vip3Aa20 Syngenta Zea mays MIR604 × SYN-IR6Ø4-5 × IR (Col)/mcry3a GA21 MON-ØØØ21-9 HT (Gly)/mepsps A191 Maize MIR162 × SYN-IR162-4 × not available IR (BL)/vip3Aa20 Syngenta Zea mays TC1507 DAS-Ø15Ø7-1 IR (BL)/cry1Fa2 HT (Glu)/pat A192 Maize MIR162 × SYN-IR162-4 × not available IR (BL)/vip3Aa20 Syngenta Zea mays TC1507 × DAS-Ø15Ø7-1 × IR (BL)/cry1Fa2 GA21 MON-ØØØ21-9 HT (Glu)/pat HT (Gly)/mepsps A193 Maize MIR604 SYN-IR6Ø4-5 Agrisure ™ RW IR (Col)/mcry3a Syngenta Zea mays A194 Maize MIR604 × SYN-IR6Ø4-5 × Agrisure ™ IR (Col)/mcry3a Syngenta Zea mays GA21 MON-ØØØ21-9 GT/RW HT (Gly)/mepsps A195 Maize MIR604 × SYN-IR6Ø4-5 × not available IR (Col)/mcry3a Dupont Zea mays NK603 MON-ØØ6Ø3-6 HT (Gly)/cp4 epsps (aroA:CP4) A196 Maize MIR604 × SYN-IR6Ø4-5 × not available IR (Col)/mcry3a Syngenta Zea mays TC1507 DAS-Ø15Ø7-1 IR (BL)/cry1Fa2 HT (Glu)/pat A197 Maize MON801 MON801 not available IR (BL)/cry1Ab Monsanto Zea mays (MON80100) A198 Maize MON802 MON-8Ø2ØØ-7 not available IR (BL)/cry1Ab Monsanto Zea mays A199 Maize MON809 PH-MON-8Ø9-2 not available IR (BL)/cry1Ab Monsanto & Zea mays Dupont A200 Maize MON810 MON-ØØ81Ø-6 YieldGard ™, IR (BL)/cry1Ab Monsanto Zea mays MaizeGard ™ A201 Maize MON810 × MON-ØØ81Ø-6 × YieldGard ™ VT IR (BL)/cry1Ab Monsanto Zea mays MON88017 MON-88Ø17-3 Triple IR (Col)/cry3Bb1 HT (Gly)/cp4 epsps (aroA:CP4) A202 Maize MON832 not available Roundup HT (Gly)/gov247 Monsanto Zea mays Ready ™ Maize HT (Gly)/cp4 epsps (aroA:CP4) A203 Maize MON863 MON-ØØ863-5 YieldGard ™ IR (Col)/cry3Bb1 Monsanto Zea mays Rootworm RW, MaxGard ™ A204 Maize MON863 × MON-ØØ863-5 × YieldGard ™ Plus IR (BL)/cry1Ab Monsanto Zea mays MON810 MON-ØØ81Ø-6 IR (Col)/cry3Bb1 A205 Maize MON863 × MON-ØØ6Ø3-6 × YieldGard ™ Plus IR (BL)/cry1Ab Monsanto Zea mays MON810 × MON-ØØ81Ø-6 × with RR IR (Col)/cry3Bb1 NK603 MON-ØØ863-5 HT (Gly)/cp4 epsps (aroA:CP4) A206 Maize MON863 × MON-ØØ863-5 × YieldGard ™ IR (Col)/cry3Bb1 Monsanto Zea mays NK603 MON-ØØ6Ø3-6 RW + RR HT (Gly)/cp4 epsps (aroA:CP4) A207 Maize MON87411 MON-87411-9 Not available IR (Col)/cry3Bb1 Monsanto Zea mays HT (Gly)/cp4 epsps (aroA:CP4) IR (Rw)/dvsnf7 A208 Maize MON87427 MON-87427-7 Roundup HT (Gly)/cp4 Monsanto Zea mays Ready ™ Maize epsps (aroA:CP4) A209 Maize MON87427 × MON-87427-7 × not available HT (Gly)/cp4 Monsanto Zea mays MON89034 × MON-89Ø34-3 × epsps (aroA:CP4) MON88017 MON-88Ø17-3 IR (BL)/cry2Ab2 IR (BL)/cry1A.105 IR (Col)/cry3Bb1 A210 Maize MON87427 × MON-87427-7 × not available HT (Gly)/cp4 Monsanto Zea mays MON89034 × MON-89Ø34-3 × epsps (aroA:CP4) NK603 MON-ØØ6Ø3-6 IR (BL)/cry2Ab2 IR (BL)/cry1A.105 A211 Maize MON87427 × MON-87427-7 × not available HT (Gly)/cp4 Monsanto Zea mays MON89Ø34 × MON-89Ø34-3 × epsps (aroA:CP4) TC15Ø7 × DAS-Ø15Ø7-1 × IR (Col)/cry34Ab1 MON88Ø17 × MON-88Ø17-3 × IR (Col)/cry35Ab1 59122 DAS-59122-7 IR (BL)/cry1Fa2 HT (Glu)/pat IR (BL)/cry2Ab2 A212 Maize MON87460 MON-8746Ø-4 Genuity ® YS (DT)/cspB Monsanto & Zea mays DroughtGard ™ BASF A213 Maize MON87460 × MON-8746Ø-4 × not available YS (DT)/cspB Monsanto Zea mays MON89034 × MON-89Ø34-3 × IR (BL)/cry1A.105 MON88017 MON-88Ø17-3 IR (BL)/cry2Ab2 IR (Col)/cry3Bb1 HT (Gly)/cp4 epsps (aroA:CP4) A214 Maize MON87460 × MON-8746Ø-4 × not available YS (DT)/cspB Monsanto Zea mays MON89034 × MON-89Ø34-3 × IR (BL)/cry1A.105 NK603 MON-ØØ6Ø3-6 IR (BL)/cry2Ab2 HT (Gly)/cp4 epsps (aroA:CP4) A215 Maize MON87460 × MON-8746Ø-4 × not available YS (DT)/cspB Monsanto Zea mays NK603 MON-ØØ6Ø3-6 HT (Gly)/cp4 epsps (aroA:CP4) A216 Maize MON88017 MON-88Ø17-3 YieldGard ™ IR (Col)/cry3Bb1 Monsanto Zea mays VT ™ HT (Gly)/cp4 Rootworm ™ epsps (aroA:CP4) RR2 A217 Maize MON89034 MON-89Ø34-3 YieldGard ™ VT IR (BL)/cry1A.105 Monsanto Zea mays Pro ™ A218 Maize MON89034 × MON-89Ø34-3 × not available HT (Glu)/pat Monsanto Zea mays 59122 DAS-59122-7 IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 IR (BL)/cry1A.105 IR (BL)/cry2Ab2 A219 Maize MON89034 × MON-89Ø34-3 × not available HT (Glu)/pat Monsanto Zea mays 59122 × DAS-59122-7 × IR (Col)/cry34Ab1 MON88017 MON-88Ø17-3 IR (Col)/cry35Ab1 IR (Col)/cry3Bb1 HT (Gly)/cp4 epsps (aroA:CP4) IR (BL)/cry1A.105 IR (BL)/cry2Ab2 A220 Maize MON89034 × MON-89Ø34-3 × Genuity ® VT IR (BL)/cry1A.105 Monsanto Zea mays MON88017 MON-88Ø17-3 Triple Pro ™ IR (BL)/cry2Ab2 IR (Col)/cry3Bb1 HT (Gly)/cp4 epsps (aroA:CP4) A221 Maize MON89034 × MON-89Ø34-3 × Genuity ® VT IR (BL)/cry1A.105 Monsanto Zea mays NK603 MON-ØØ6Ø3-6 Double Pro ™ IR (BL)/cry2Ab2 HT (Gly)/cp4 epsps (aroA:CP4) A222 Maize MON89034 × MON-89Ø34-3 × not available IR (BL)/cry1A.105 Monsanto Zea mays TC1507 DAS-Ø15Ø7-1 IR (BL)/cry2Ab2 IR (BL)/cry1Fa2 HT (Glu)/pat A223 Maize MON89034 × MON-89Ø34-3 × not available HT (Glu)/pat Monsanto Zea mays TC1507 × DAS-Ø15Ø7-1 × IR (Col)/cry34Ab1 59122 DAS-59122-7 IR (Col)/cry35Ab1 IR (BL)/cry1A.105 IR (BL)/cry2Ab2 IR (BL)/cry1Fa2 A224 Maize MON89034 × MON-89Ø34-3 × not available IR (Col)/cry3Bb1 Monsanto & Zea mays TC1507 × DAS-Ø15Ø7-1 × HT (Gly)/cp4 Dow MON88017 MON-88Ø17-3 epsps (aroA:CP4) IR (BL)/cry1A.105 IR (BL)/cry2Ab2 IR (BL)/cry1Fa2 HT (Glu)/pat A225 Maize MON89034 × MON-89Ø34-3 × Genuity ® HT (Glu)/pat Monsanto & Zea mays TC1507 × DAS-Ø15Ø7-1 × SmartStax ™ IR (Col)/cry34Ab1 Dow MON88017 × MON-88Ø17-3 × IR (Col)/cry35Ab1 59122 DAS-59122-7 IR (Col)/cry3Bb1 HT (Gly)/cp4 epsps (aroA:CP4) IR (BL)/cry1A.105 IR (BL)/cry2Ab2 IR (BL)/cry1Fa2 A226 Maize MON89034 × MON-89Ø34-3 × not available HT (Glu)/pat Dow Zea mays TC1507 × DAS-Ø15Ø7-1 × IR (Col)/cry34Ab1 MON88017 × MON-88Ø17-3 × IR (Col)/cry35Ab1 59122 × DAS-59122-7 × IR (Col)/cry3Bb1 DAS40278 DAS-4Ø278-9 HT (Gly)/cp4 epsps (aroA:CP4) IR (BL)/cry1A.105 IR (BL)/cry2Ab2 IR (BL)/cry1Fa2 HT (2,4-D)/aad1 A227 Maize MON89034 × MON-89Ø34-3 × not available IR (Col)/cry3Bb1 Dow Zea mays TC1507 × DAS-Ø15Ø7-1 × HT (Gly)/cp4 MON88017 × MON-88Ø17-3 × epsps (aroA:CP4) DAS40278 DAS-59122-7 × IR (BL)/cry1A.105 DAS-4Ø278-9 IR (BL)/cry2Ab2 IR (BL)/cry1Fa2 HT (Glu)/pat HT (2,4-D)/aad1 A228 Maize MON89034 × MON-89Ø34-3 × Power Core ™ IR (BL)/cry1A.105 Monsanto & Zea mays TC1507 × DAS-Ø15Ø7-1 × IR (BL)/cry2Ab2 Dow NK603 MON-ØØ6Ø3-6 IR (BL)/cry1Fa2 HT (Gly)/cp4 epsps (aroA:CP4) HT (Glu)/pat A229 Maize MON89034 × MON-89Ø34-3 × not available IR (BL)/cry1A.105 Dow Zea mays TC1507 × DAS-Ø15Ø7-1 × IR (BL)/cry2Ab2 NK603 × MON-ØØ6Ø3-6 × IR (BL)/cry1Fa2 DAS40278 DAS-4Ø278-9 HT (Gly)/cp4 epsps (aroA:CP4) HT (Glu)/pat HT (2,4-D)/aad1 A230 Maize MS3 ACS-ZMØØ1-9 InVigor ™ Maize PC (MS)/barnase Bayer Crop Zea mays Science A231 Maize MS6 ACS-ZMØØ5-4 InVigor ™ Maize PC (MS)/barnase Bayer Crop Zea mays Science A232 Maize NK603 MON-ØØ6Ø3-6 Roundup HT (Gly)/cp4 Monsanto Zea mays Ready ™ 2 Maize epsps (aroA:CP4) A233 Maize NK603 × MON-00603-6 × Not available HT (Gly)/cp4 Syngenta & Zea mays MON810 × MON-00810-6 × epsps (aroA:CP4) Monsanto 4114 × DP004114-3 × IR (BL)/cry1Ab MIR 604 SYN-IR604-4 IR (BL)/cry1F IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 HT (Glu)/pat A234 Maize NK603 × MON-ØØ6Ø3-6 × YieldGard ™ IR (BL)/cry1Ab Monsanto Zea mays MON810 MON-ØØ81Ø-6 CB + RR HT (Gly)/cp4 epsps (aroA:CP4) A235 Maize NK603 × MON-ØØ6Ø3-6 × Roundup HT (Gly)/cp4 Monsanto Zea mays T25 ACS-ZMØØ3-2 Ready ™ Liberty epsps (aroA:CP4) Link ™ Maize HT (Glu)/pat (syn) A236 Maize T14 ACS-ZMØØ2-1 Liberty Link ™ HT (Glu)/pat (syn) Bayer Crop Zea mays Maize Science A237 Maize T25 ACS-ZMØØ3-2 Liberty Link ™ HT (Glu)/pat (syn) Bayer Crop Zea mays Maize Science A238 Maize T25 × ACS-ZMØØ3-2 × Liberty Link ™ IR (BL)/cry1Ab Bayer Crop Zea mays MON810 MON-ØØ81Ø-6 Yieldgard ™ HT (Glu)/pat (syn) Science & Maize Monsanto A239 Maize TC1507 DAS-Ø15Ø7-1 Herculex ™ I, IR (BL)/cry1Fa2 Dow & Zea mays Herculex ™ CB HT (Glu)/pat Dupont A240 Maize TC1507 × DAS-Ø15Ø7-1 × Optimum ™ IR (BL)/cry1Fa2 Dupont Zea mays 59122 × DAS-59122-7 × Intrasect Xtreme HT (Glu)/pat MON810 × MON-ØØ81Ø-6 × IR (Col)/cry34Ab1 MIR604 × SYN-IR6Ø4-5 × IR (Col)/cry35Ab1 NK603 MON-ØØ6Ø3-6 A241 Maize TC1507 × DAS-Ø15Ø7-1 × not available IR (Col)/mcry3A Dupont Zea mays MON810 × MON-ØØ81Ø-6 × IR (BL)/cry1Fa2 MIR604 × SYN-IR6Ø4-5 × HT (Glu)/pat NK603 MON-ØØ6Ø3-6 IR (BL)/cry1Ab HT (Gly)/cp4 epsps (aroA:CP4) A242 Maize TC1507 × DAS-Ø15Ø7-1 × Herculex IR (BL)/cry1Fa2 Dow & Zea mays 59122 DAS-59122-7 XTRA ™ HT (Glu)/pat Dupont IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 A243 Maize TC1507 × DAS-Ø15Ø7-1 × not available IR (BL)/cry1Fa2 Dupont Zea mays 59122 × DAS-59122-7 × HT (Glu)/pat MON810 MON-ØØ81Ø-6 IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 IR (BL)/cry1Ab A244 Maize TC1507 × DAS-Ø15Ø7-1 × Optimum ™ IR (BL)/cry1Fa2 Dupont Zea mays 59122 × DAS-59122-7 × Intrasect XTRA HT (Glu)/pat MON810 × MON-ØØ81Ø-6 × IR (Col)/cry34Ab1 NK603 MON-ØØ6Ø3-6 IR (Col)/cry35Ab1 HT (Gly)/cp4 epsps (aroA:CP4) IR (BL)/cry1Ab A245 Maize TC1507 × DAS-Ø15Ø7-1 × not available IR (BL)/cry1Fa2 Monsanto & Zea mays 59122 × DAS-59122-7 × HT (Glu)/pat Dow MON88017 MON-88Ø17-3 IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 IR (Col)/cry3Bb1 HT (Gly)/cp4 epsps (aroA:CP4) A246 Maize TC1507 × DAS-Ø15Ø7-1 × Herculex IR (BL)/cry1Fa2 Dow & Zea mays 59122 × DAS-59122-7 × XTRA ™ RR HT (Glu)/pat Dupont NK603 MON-ØØ6Ø3-6 IR (Col)/cry34Ab1 IR (Col)/cry35Ab1 HT (Gly)/cp4 epsps (aroA:CP4) A247 Maize TC1507 × DAS-Ø15Ø7-1 × not available IR (BL)/cry1Fa2 Dupont Zea mays GA21 MON-ØØØ21-9 HT (Glu)/pat HT (Gly)/mepsps A248 Maize TC1507 × DAS-Ø15Ø7-1 × Optimum ™ IR (BL)/cry1Fa2 Dupont Zea mays MIR604 × SYN-IR6Ø4-5 × TRIsect HT (Glu)/pat NK603 MON-ØØ6Ø3-6 HT (Gly)/cp4 epsps (aroA:CP4) IR (Col)/mcry3A A249 Maize TC1507 × DAS-Ø15Ø7-1 × not available IR (BL)/cry1Fa2 Dow & Zea mays MON810 MON-ØØ81Ø-6 HT (Glu)/pat Dupont IR (BL)/cry1Ab A250 Maize TC1507 × DAS-Ø15Ø7-1 × not available IR (BL)/cry1Fa2 Dupont Zea mays MON810 × MON-ØØ81Ø-6 × HT (Glu)/pat MIR162 × SYN-IR162-4 × IR (BL)/cry1Ab NK603 MON-ØØ6Ø3-6 HT (Gly)/cp4 epsps (aroA:CP4) IR (BL)/vip3Aa20 A251 Maize TC1507 × DAS-Ø15Ø7-1 × Optimum ™ IR (BL)/cry1Fa2 Dupont Zea mays MON810 × MON-ØØ81Ø-6 × Intrasect HT (Glu)/pat NK603 MON-ØØ6Ø3-6 IR (BL)/cry1Ab HT (Gly)/cp4 epsps (aroA:CP4) A252 Maize TC1507 × DAS-Ø15Ø7-1 × not available IR (BL)/cry1Fa2 Monsanto Zea mays MON88017 MON-88Ø17-3 HT (Glu)/pat IR (Col)/cry3Bb1 HT (Gly)/cp4 epsps (aroA:CP4) A253 Maize TC1507 × DAS-Ø15Ø7-1 × Herculex ™ I RR IR (BL)/cry1Fa2 Dow Zea mays NK603 MON-ØØ6Ø3-6 HT (Glu)/pat HT (Gly)/cp4 epsps (aroA:CP4) A254 Maize TC6275 DAS-Ø6275-8 not available IR (BL)/mocry1F Dow Zea mays HT (Glu)/bar A255 Maize VCO- VCO-Ø1981-5 not available HT (Gly)/epsps Genective Zea mays Ø1981-5 grg23ace5 S.A. A256 Maize DK404SR DK404SR not available HT (Cyc)/ACCase BASF Zea mays (mutant) A257 Maize EXP1910IT EXP1910IT not available HT (Imi)/als Syngenta Zea mays (mutant) A258 Melon Melon A not available not available ST (Ripe)/sam-k Agritope Inc. Cucumis melo (USA) A259 Melon Melon B not available not available ST (Ripe)/sam-k Agritope Inc. Cucumis melo (USA) A260 Papaya 55-1 CUH-CP551-8 Rainbow, SunUp VR (PRSV)/prsv-cp Cornell Uni- Carica papaya versity and University of Hawaii A261 Papaya 63-1 CUH-CP631-7 not available VR (PRSV)/prsv-cp Cornell Uni- Carica papaya versity and University of Hawaii A262 Papaya Huanong not available Huanong No. 1 VR (PRSV)/prsv-rep South China Carica papaya No. 1 Agricultural University A263 Papaya X17-2 UFL-X17CP-6 not available VR (PRSV)/prsv-cp University of Carica papaya Florida A264 Petunia Petunia- not available not available Beijing Petunia hybrida CHS University A265 Plum C-5 ARS-PLMC5-6 not available VR (PPV)/ppv-cp United Prunus domestica States De- partment of Agriculture - Agricultural Research Service A266 Polish canola HCR-1 not available not available HT (Glu)/pat Bayer Crop Brassica rapa Sciences A267 Polish canola ZSR500 not available Hysyn 101 RR HT (Gly)/cp4 University of Brassica rapa Roundup- epsps (aroA:CP4) Florida Ready ™ HT (Gly)/gov247 A268 Polish canola ZSR502 not available Hysyn 101 RR HT (Gly)/cp4 University of Brassica rapa Roundup- epsps (aroA:CP4) Florida Ready ™ HT (Gly)/gov247 A269 Polish canola ZSR503 not available Hysyn 101 RR HT (Gly)/cp4 University of Brassica rapa Roundup- epsps (aroA:CP4) Florida Ready ™ HT (Gly)/gov247 A270 Poplar Bt poplar, not available not available IR (BL)/cry1Ac Research Populus sp. poplar 12 Institute of (Populus Forestry nigra) (China) A271 Poplar Hybrid poplar not available not available IR (BL)/cry1Ac Research Populus sp. clone 741 IR (BRun)/API Institute of Forestry (China) A272 Potato 1210 amk not available Lugovskoi plus IR (Col)/cry3A Centre Bio- Solanum tuberosum engineering, Russian Academy of Sciences A273 Potato 2904/1 kgs not available Elizaveta plus IR (Col)/cry3A Centre Bio- Solanum tuberosum engineering, Russian Academy of Sciences A274 Potato ATBT04-27 NMK-89367-8 Atlantic IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ potato A275 Potato ATBT04-30 NMK-89613-2 Atlantic IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ potato A276 Potato ATBT04-31 NMK-8917Ø-9 Atlantic IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ potato A277 Potato ATBT04-36 NMK-89279-1 Atlantic IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ potato A278 Potato ATBT04-6 NMK-89761-6 Atlantic IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ potato A279 Potato BT06 NMK-89812-3 New Leaf ™ IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank potato A280 Potato BT10 NMK-89175-5 New Leaf ™ IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank potato A281 Potato BT12 NMK-896Ø1-8 New Leaf ™ IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank potato A282 Potato BT16 NMK-89167-6 New Leaf ™ IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank potato A283 Potato BT17 NMK-89593-9 New Leaf ™ IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank potato A284 Potato BT18 NMK-899Ø6-7 New Leaf ™ IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank potato A285 Potato BT23 NMK-89675-1 New Leaf ™ IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank potato A286 Potato EH92-527-1 BPS-25271-9 Amflora ™ ST (Starch)/gbss BASF Solanum tuberosum (antisense- fragment) A287 Potato HLMT15-15 not available Hi-Lite IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ Y VR (PVY)/pvy-cp potato A288 Potato HLMT15-3 not available Hi-Lite IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ Y VR (PVY)/pvy-cp potato A289 Potato HLMT15-46 not available Hi-Lite IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ Y VR (PVY)/pvy-cp potato A290 Potato RBMT15-101 NMK-89653-6 New Leaf ™ Y IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank VR (PVY)/pvy-cp potato A291 Potato RBMT21-129 NMK-89684-1 New Leaf ™ Plus IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank VR (PLRV)/plrv-orf1 potato VR (PLRV)/plrv-orf2 A292 Potato RBMT21-152 not available New Leaf ™ Plus IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank VR (PLRV)/plrv-orf1 potato VR (PLRV)/plrv-orf2 A293 Potato RBMT21-350 NMK-89185-6 New Leaf ™ Plus IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank VR (PLRV)/plrv-orf1 potato VR (PLRV)/plrv-orf2 A294 Potato RBMT22-082 NMK-89896-6 New Leaf ™ Plus IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank HT (Gly)/cp4 potato epsps (aroA:CP4) VR (PLRV)/plrv-orf1 VR (PLRV)/plrv-orf2 A295 Potato RBMT22-186 not available New Leaf ™ Plus IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank HT (Gly)/cp4 potato epsps (aroA:CP4) VR (PLRV)/plrv-orf1 VR (PLRV)/plrv-orf2 A296 Potato RBMT22-238 not available New Leaf ™ Plus IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank HT (Gly)/cp4 potato epsps (aroA:CP4) VR (PLRV)/plrv-orf1 VR (PLRV)/plrv-orf2 A297 Potato RBMT22-262 not available New Leaf ™ Plus IR (Col)/cry3A Monsanto Solanum tuberosum Russet Burbank HT (Gly)/cp4 potato epsps (aroA:CP4) VR (PLRV)/plrv-orf1 VR (PLRV)/plrv-orf2 A298 Potato SEMT15-02 NMK-89935-9 Shepody IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ Y VR (PVY)/pvy-cp potato A299 Potato SEMT15-07 not available Shepody IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ Y VR (PVY)/pvy-cp potato A300 Potato SEMT15-15 NMK-8993Ø-4 Shepody IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ Y VR (PVY)/pvy-cp potato A301 Potato SPBT02-5 NMK-89576-1 Superior IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ potato A302 Potato SPBT02-7 NMK-89724-5 Superior IR (Col)/cry3A Monsanto Solanum tuberosum NewLeaf ™ potato A303 Potato E12 SPS-ØØE12-8 Innate ™ Russet ST (AA)/asn1 J.R. Simplot Solanum tuberosum Burbank Potato ST (Starch)/pPhL Co. ST (BSB)/ppo5 ST (Starch)/pR1 A304 Potato E24 SPS-ØØE24-2 Innate ™ Russet ST (AA)/asn1 J.R. Simplot Solanum tuberosum Burbank Potato ST (Starch)/pPhL Co. ST (BSB)/ppo5 ST (Starch)/pR1 A305 Potato F10 SPS-ØØF10-7 Innate ™ Ranger ST (AA)/asn1 J.R. Simplot Solanum tuberosum Russet Potato ST (Starch)/pPhL Co. ST (BSB)/ppo5 ST (Starch)/pR1 A306 Potato F37 SPS-ØØF37-7 Innate ™ Ranger ST (AA)/asn1 J.R. Simplot Solanum tuberosum Russet Potato ST (Starch)/pPhL Co. ST (BSB)/ppo5 ST (Starch)/pR1 A307 Potato G11 SPS-ØØG11-9 Innate ™ G ST (AA)/asn1 J.R. Simplot Solanum tuberosum Potato ST (BSB)/ppo5 Co. A308 Potato H37 SPS-ØØH37-9 Innate ™ H ST (AA)/asn1 J.R. Simplot Solanum tuberosum Potato ST (Starch)/pPhL Co. ST (BSB)/ppo5 ST (Starch)/pR1 A309 Potato H50 SPS-ØØH50-4 Innate ™ H ST (AA)/asn1 J.R. Simplot Solanum tuberosum Potato ST (Starch)/pPhL Co. ST (BSB)/ppo5 ST (Starch)/pR1 A310 Potato J3 SPS-ØØØJ3-4 Innate ™ Atlantic ST (AA)/asn1 J.R. Simplot Solanum tuberosum Potato ST (Starch)/pPhL Co. ST (BSB)/ppo5 ST (Starch)/pR1 A311 Potato J55 SPS-ØØJ55-2 Innate ™ Atlantic ST (AA)/asn1 J.R. Simplot Solanum tuberosum Potato ST (Starch)/pPhL Co. ST (BSB)/ppo5 ST (Starch)/pR1 A312 Potato J78 SPS-ØØJ78-7 Innate ™ Atlantic ST (AA)/asn1 J.R. Simplot Solanum tuberosum Potato ST (BSB)/ppo5 Co. A313 Rice 7Crp#10 not available not available ST (All)/7crp National Oryza sativa Institute of Agrobiolog- ical Sciences (Japan) A314 Rice GM not available BT Shanyou 63 IR (BL)/cry1Ab Huazhong Oryza sativa Shanyou 63 IR (BL)/cry1Ac Agricultural University (China) A315 Rice Huahui-1/ not available Huahui-1 IR (BL)/cry1Ab Huazhong Oryza sativa TT51-1 IR (BL)/cry1Ac Agricultural University (China) A316 Rice LLRICE06 ACS-OSØØ1-4 Liberty Link ™ HT (Glu)/bar Bayer Crop Oryza sativa rice Science A317 Rice LLRICE601 BCS-OSØØ3-7 Liberty Link ™ HT (Glu)/bar Bayer Crop Oryza sativa rice Science A318 Rice LLRICE62 ACS-OSØØ2-5 Liberty Link ™ HT (Glu)/bar Bayer Crop Oryza sativa rice Science A319 Rice Tarom molaii + not available not available IR (BL)/cry1Ab Agricultural Oryza sativa cry1Ab (truncated) Biotech Re- search Insti- tute (Iran) A320 Rice CL121, CL141, CL121, CL141, CFX51 Clearfield Rice HT (Imi)/als BASF Oryza sativa CFX51 (mutant) A321 Rice IMINTA-1, IMINTA-1, IMINTA-4 Clearfield Rice HT (Imi)/als BASF Oryza sativa IMINTA-4 (mutant) A322 Rice PWC16 PWC16 not available HT (Imi)/als BASF Oryza sativa (mutant) A323 Rose WKS82/130-4-1 IFD-524Ø1-4 not available ST (Color)/5AT Suntory Rosa hybrida ST (Color)/bp40 Limited (f3′5′h) (Japan) A324 Rose WKS92/130-9-1 IFD-529Ø1-9 not available ST (Color)/5AT Suntory Rosa hybrida ST (Color)/bp40 Limited (f3′5′h) (Japan) A325 Soybean 260-05 (G94-1, DD-Ø26ØØ5-3 not available ST (Oil)/gm-fad2-1 Dupont Glycine max G94-19, G168) (silencing locus) A326 Soybean A2704-12 ACS-GMØØ5-3 Liberty Link ™ HT (Glu)/pat Bayer Crop Glycine max soybean Science A327 Soybean A2704-21 ACS-GMØØ4-2 Liberty Link ™ HT (Glu)/pat Bayer Crop Glycine max soybean Science A328 Soybean A5547-127 ACS-GMØØ6-4 Liberty Link ™ HT (Glu)/pat Bayer Crop Glycine max soybean Science A329 Soybean A5547-35 ACS-GMØØ8-6 Liberty Link ™ HT (Glu)/pat Bayer Crop Glycine max soybean Science A330 Soybean CV127 BPS-CV127-9 Cultivance HT (Imi)/csr1-2 BASF Glycine max A331 Soybean DAS44406-6 DAS-444Ø6-6 not available HT (2,4-D)/aad-12 Dow Glycine max HT (Gly)/2mepsps HT (Glu)/pat A332 Soybean DAS68416-4 DAS-68416-4 Enlist ™ Soybean HT (2,4-D)/aad-12 Dow Glycine max HT (Glu)/pat A333 Soybean DAS68416-4 × DAS-68416-4 × not available HT (2,4-D)/aad-12 Dow Glycine max MON89788 MON-89788-1 HT (Glu)/pat HT (Gly)/cp4 epsps (aroA:CP4) A334 Soybean DAS81419 DAS-81419-2 not available IR (BL)/cry1Ac Dow Glycine max IR (BL)/cry1F HT (Glu)/pat A335 Soybean DP305423 DP-3Ø5423-1 Treus ™, ST (Oil)/gm-fad2-1 Dupont Glycine max Plenish ™ (partial sequence) A336 Soybean DP305423 × DP-3Ø5423-1 × not available ST (Oil)/gm-fad2-1 Dupont Glycine max GTS 40-3-2 MON-Ø4Ø32-6 (partial sequence) HT (Gly)/cp4 epsps (aroA:CP4) A337 Soybean DP356043 DP-356Ø43-5 Optimum GAT ™ HT (Gly)/gat4601 Dupont Glycine max HT (SU)/gm-hra A338 Soybean FG72 MST-FGØ72-3 not available HT (Gly)/2mepsps Bayer Crop- Glycine max (FGØ72-2, HT (HPPD)/hppdPF Science and FGØ72-3) W336 MS Tech- nologies LLC A339 Soybean GTS 40-3-2 MON-Ø4Ø32-6 Roundup HT (Gly)/cp4 Monsanto Glycine max (40-3-2) Ready ™ epsps (aroA:CP4) soybean A340 Soybean GU262 ACS-GMØØ3-1 Liberty Link ™ HT (Glu)/pat Bayer Crop Glycine max soybean Science A341 Soybean MON 87712 MON-87712-4 Not available Y&S (Y)/bbx32 Monsanto Glycine max A342 Soybean MON87701 MON-877Ø1-2 not available IR (BL)/cry1Ac Monsanto Glycine max A343 Soybean MON87701 × MON-877Ø1-2 × Intacta ™ IR (BL)/cry1Ac Monsanto Glycine max MON89788 MON-89788-1 Roundup HT (Gly)/cp4 Ready ™ 2 Pro epsps (aroA:CP4) A344 Soybean MON87705 MON-877Ø5-6 Vistive Gold ™ ST (Oil)/fatb1-A Monsanto Glycine max (sense and anti- sense segments) ST (Oil)/fatb2-1-A (sense and anti- sense) HT (Gly)/cp4 epsps (aroA:CP4) A345 Soybean MON87705 × MON-877Ø5-6 × not available ST (Oil)/fatb1-A Monsanto Glycine max MON89788 MON-89788-1 (sense and anti- sense segments) ST (Oil)/fatb2-1-A (sense and anti- sense) HT (Gly)/cp4 epsps (aroA:CP4) A346 Soybean MON87708 MON-877Ø8-9 Genuity ® HT (Dic)/dmo Monsanto Glycine max Roundup Ready ™ 2 Xtend ™ A347 Soybean MON87708 × MON-877Ø8-9 × not available HT (Dic)/dmo Monsanto Glycine max MON89788 MON-89788-1 HT (Gly)/cp4 epsps (aroA:CP4) A348 Soybean MON87751 MON-87751-7 not available IR (BL)/cry1A.105 Monsanto Glycine max IR (BL)/cry2Ab2 A349 Soybean MON87769 MON87769-7 not available ST (Oil)/Pj.D6D Monsanto Glycine max ST (Oil)/Nc.fad3 A350 Soybean MON87769 × MON-87769-7 × not available ST (Oil)/Pj.D6D Monsanto Glycine max MON89788 MON-89788-1 ST (Oil)/Nc.fad3 HT (Gly)/cp4 epsps (aroA:CP4) A351 Soybean MON89788 MON-89788-1 Genuity ® HT (Gly)/cp4 Monsanto Glycine max Roundup Ready epsps (aroA:CP4) 2 Yield ™ A352 Soybean SYHTØH2 SYN-ØØØH2-5 Herbicide- HT (Glu)/pat Bayer Crop Glycine max tolerant Soybean HT (HPPD)/avhppd-03 Science & line Syngenta A353 Soybean W62 ACS-GMØØ2-9 Liberty Link ™ HT (Glu)/bar Bayer Crop Glycine max soybean Science A354 Soybean W98 ACS-GMØØ1-8 Liberty Link ™ HT (Glu)/bar Bayer Crop Glycine max soybean Science A355 Soybean OT96-15 OT96-15 not available ST (Oil)/fan1 (mutant) Agriculture & Glycine max Agri-Food Canada A356 Squash CZW3 SEM-ØCZW3-2 not available VR (CMV)/cmv-cp Seminis Cucurbita pepo VR (zymv)/zymv-cp Vegetable VR (wmv)/wmv-cp Seeds (Canada) and Monsanto Company (As-grow) A357 Squash ZW20 SEM-ØZW2Ø-7 not available VR (CYMV)/zymv-cp Seminis Cucurbita pepo VR (WMV)/wmv-cp Vegetable Seeds (Canada) and Monsanto Company (As-grow) A358 Sugar beet GTSB77 SY-GTSB77-8 InVigor ™ HT (Gly)/cp4 Novartis Beta vulgaris (T9100152) sugarbeet epsps (aroA:CP4) Seeds and HT (Gly)/gov247 Monsanto Company A359 Sugar beet H7-1 KM-ØØØH71-4 Roundup HT (Gly)/cp4 Monsanto Beta vulgaris Ready ™ sugar epsps (aroA:CP4) beet A360 Sugar beet T120-7 ACS-BVØØ1-3 Liberty Link ™ HT (Glu)/pat Bayer Crop Beta vulgaris sugarbeet Science A361 Sugarcane NXI-1T NXI-1T not available Y&S (DT)/EcBetA PT Saccharum sp. Perkebunan Nusantara XI (Persero) A362 Sugarcane NXI-4T NXI-4T not available Y&S (DT)/RmBetA PT Saccharum sp. Perkebunan Nusantara XI (Persero) A363 Sugarcane NXI-6T NXI-6T not available Y&S (DT)/RmBetA PT Saccharum sp. Perkebunan Nusantara XI (Persero) A364 Sunflower X81359 X81359 Clearfield HT (Imi)/als BASF Helianthus annuus Sunflower (mutant) A365 Sweet pepper PK-SP01 not available not available VR (CMV)/cmv-cp Beijing Capsicum annuum University A366 Tobacco C/F/93/08-02 not available not available HT (Ox)/bxn SEITA S.A. Nicotiana tabacum (France) A367 Tobacco Vector 21-41 not available not available ST (Nic)/NtQPT1 Vector Nicotiana tabacum (antisense) Tobacco Inc. (USA) A368 Tomato 1345-4 not available not available ST (Ripe)/acc DNA Plant Lycopersicon (truncated) Technology esculentum Corporation (USA) A369 Tomato 35-1-N not available not available ST (Ripe)/sam-k Agritope Inc. Lycopersicon (USA) esculentum A370 Tomato 5345 not available not available IR (BL)/cry1Ac Monsanto Lycopersicon esculentum A371 Tomato 8338 CGN-89322-3 not available ST (Ripe)/accd Monsanto Lycopersicon esculentum A372 Tomato B SYN-ØØØØB-6 not available ST (Ripe)/pg Zeneca Lycopersicon (sense or antisense) Plant Sci- esculentum ence and Petoseed Company A373 Tomato Da SYN-ØØØDA-9 not available ST (Ripe)/pg Zeneca Lycopersicon (sense or antisense) Plant Sci- esculentum ence and Petoseed Company A374 Tomato Da Dong No 9 not available not available Institute of Lycopersicon Microbiolo- esculentum gy, CAS (China) A375 Tomato F (1401F, SYN-ØØØØF-1 not available ST (Ripe)/pg Zeneca Lycopersicon h38F, 11013F, (sense or antisense) Plant Sci- esculentum 7913F) ence and Petoseed Company A376 Tomato FLAVR CGN-89564-2 FLAVR SAVR ST (Ripe)/pg Monsanto Lycopersicon SAVR ™ (sense or antisense) esculentum A377 Tomato Huafan No 1 not available not available ST (Ripe)/anti-efe Huazhong Lycopersicon Agricultural esculentum University (China) A378 Tomato PK-TM8805R not available not available VR (CMV)/cmv-cp Beijing Lycopersicon (8805R) University esculentum A379 Wheat MON71800 MON-718ØØ-3 Roundup HT (Gly)/cp4 Monsanto Triticum aestivum Ready ™ wheat epsps (aroA:CP4) A380 Wheat AP205CL AP205CL Clearfield Wheat HT (Imi)/als BASF Triticum aestivum (mutant) A381 Wheat AP602CL AP602CL Clearfield Wheat HT (Imi)/als BASF Triticum aestivum (mutant) A382 Wheat BW255-2, BW255-2, BW238-3 Clearfield Wheat HT (Imi)/als BASF Triticum aestivum BW238-3 (mutant) A383 Wheat BW7 BW7 Clearfield Wheat HT (Imi)/als BASF Triticum aestivum (mutant) A384 Wheat Teal 11A Teal 11A Clearfield Wheat HT (Imi)/als BASF Triticum aestivum (mutant) A385 Wheat SWP965001 SWP965001 not available HT (Imi)/als American Triticum aestivum (mutant) Cyanamid -
-
TRAIT TRAIT - full name TRAIT TYPE TRAIT TYPE - full name HT Herbicide Tolerance HT (Gly) glyphosate tolerance HT (Glu) glufosinate tolerance HT (SU) sulfonylurea tolerance HT (Imi) imidazolinone tolerance HT (2,4-D) resistance against 2,4-D Choline HT (Dic) dicamba tolerance HT (Gly + Dicamba) glyphosate & dicamba tolerance HT (HPPD) HPPD inhibitor resistance HT (Ox) oxynil herbicide tolerance (e.g. bronnoxynil) HT (Cyc) cyclohexanone herbicide tolerance (e.g. sethoxydim) 2HT two genes for same HT-trait IR Insect resistance (including IR (BL) broad spectrum resistance against lepidopterans (above ground Nematodes) worms) IR (Col) resistance against Coleopterans (beetles) IR (SCN) soybean Cyst Nematode resistance IR (CB) corn borer resistance IR (BRun) broad range resistance, not further specified IR (Rw) resistance against root worm PC Pollination control and PC (FR) fertility restoration male sterility systems PC (MS) male sterility FR Fungal resistance FR (SR) stalk rot resistance VR Viral resistance VR (BGMV) resistance to Bean Golden Mosaic Virus VR (PRSV) resistance to papaya ringspot virus VR (PPV) resistance to plum pox virus VR (PVY) resistance to potato virus Y VR (PLRV) resistance to potato leafroll virus VR (CMV) resistance to cucumber mosaic cucumovirus VR (ZYMV) resistance to zucchini yellow mosaic potyvirus VR (WMV) resistance to watermelon mosaic potyvirus 2 Y&S Yield and Stress Y&S (DT) drought tolerance Y&S (Y) yield increase Y&S (NUE) nitrogen use efficiency ST Specialty Trait (includes Feed, ST (Lignin) altered lignin production Food, Quality) ST (OIL) altered oil content ST (starch) altered starch content ST (CA) corn amylase ST (P) phytase production ST (Color) modified color ST (Ripe) delayed/altered ripening ST (AA) altered amino-acid content ST (All) anti-allergy ST (Nic) altered nicotin content ST (BSB) reduced black spot bruise formation SM Selectable marker - Preferably, the plant, which has been modified by mutagenesis or genetic engineering, is selected from the group consisting of wheat, maize, rice, soybean, and cotton, and is more preferably a soybean plant, particularly any one of the soybean plants according to rows A-325 to A355 of table A.
- In a preferred embodiment of the use or method as defined above, the plant, which has been modified by mutagenesis or genetic engineering, is a soybean plant exhibiting insect resistence, in particular Lepidopteran resistance, and optionally at least one further trait, preferably herbicide tolerance, e.g. glyphosate tolerance or glufosinate tolerance.
- Preferred soybean plants include the soybean plants according to one row of table B.
-
TABLE B Developer/ No Trait(s) Event name commercial plants B-1 Glufosinate tolerance + DAS81419 Dow AgroSciences Lepidopteran resistance LLC B-2 Lepidopteran resistance MON87701 Monsanto Company B-3 Glyphosate tolerance + MON87701 × available, Monsanto Company; Intacta ™ Lepidopteran resistance MON89788 Roundup Ready ™ 2 Pro B-4 Lepidopteran resistance MON87751 Monsanto Company - In another preferred embodiment of the use or method as defined above, the plant, which has been modified by mutagenesis or genetic engineering, is a soybean plant, which has been modified by genetic engineering by integrating one or more genes into the genetic material of the soybean, wherein insect resistance is provided by one or more genes selected from the group consisting of cry1Ac, cry1F, cry1A.105, cry2Ab2, and combinations thereof, preferably by cry1Ac, cry1F, or a combination thereof, and more preferably by cry1Ac. Optionally, herbicide tolerance is additionally provided by one or more genes selected from the group consisting of pat, bar, 2mepsps, cp4 epsps, and mepsps.
- Preferred soybean plants include soybean plants, which have been modified by integrating at least one gene or gene combination according to one row of Table C.
-
TABLE C Gene for Gene for Gene for Gene for lepidopteran lepidopteran lepidopteran herbicide No resistance resistance resistance tolerance C-1 cry1Ac C-2 cry1A.105 C-3 cry2Ab2 C-4 cry1F C-5 cry1Ac cry1A.105 C-6 cry1Ac cry2Ab2 C-7 cry1Ac cry1F C-8 cry1A.105 cry2Ab2 C-9 cry1A.105 cry1F C-10 cry2Ab2 cry1F C-11 cry1Ac cry1A.105 cry2Ab2 C-12 cry1F cry1A.105 cry2Ab2 C-13 cry1Ac cry1F cry2Ab2 C-14 cry1Ac cry1A.105 cry1F C-15 cry1Ac pat C-16 cry1A.105 pat C-17 cry2Ab2 pat C-18 cry1F pat C-19 cry1Ac cry1A.105 pat C-20 cry1Ac cry2Ab2 pat C-21 cry1Ac cry1F pat C-22 cry1A.105 cry2Ab2 pat C-23 cry1A.105 cry1F pat C-24 cry2Ab2 cry1F pat C-25 cry1Ac cry1A.105 cry2Ab2 pat C-26 cry1F cry1A.105 cry2Ab2 pat C-27 cry1Ac cry1F cry2Ab2 pat C-28 cry1Ac cry1A.105 cry1F pat C-29 cry1Ac bar C-30 cry1A.105 bar C-31 cry2Ab2 bar C-32 cry1F bar C-33 cry1Ac cry1A.105 bar C-34 cry1Ac cry2Ab2 bar C-35 cry1Ac cry1F bar C-36 cry1A.105 cry2Ab2 bar C-37 cry1A.105 cry1F bar C-38 cry2Ab2 cry1F bar C-39 cry1Ac cry1A.105 cry2Ab2 bar C-40 cry1F cry1A.105 cry2Ab2 bar C-41 cry1Ac cry1F cry2Ab2 bar C-42 cry1Ac cry1A.105 cry1F bar C-43 cry1Ac 2mepsps C-44 cry1A.105 2mepsps C-45 cry2Ab2 2mepsps C-46 cry1F 2mepsps C-47 cry1Ac cry1A.105 2mepsps C-48 cry1Ac cry2Ab2 2mepsps C-49 cry1Ac cry1F 2mepsps C-50 cry1A.105 cry2Ab2 2mepsps C-51 cry1A.105 cry1F 2mepsps C-52 cry2Ab2 cry1F 2mepsps C-53 cry1Ac cry1A.105 cry2Ab2 2mepsps C-54 cry1F cry1A.105 cry2Ab2 2mepsps C-55 cry1Ac cry1F cry2Ab2 2mepsps C-56 cry1Ac cry1A.105 cry1F 2mepsps C-57 cry1Ac cp4 epsps C-58 cry1A.105 cp4 epsps C-59 cry2Ab2 cp4 epsps C-60 cry1F cp4 epsps C-61 cry1Ac cry1A.105 cp4 epsps C-62 cry1Ac cry2Ab2 cp4 epsps C-63 cry1Ac cry1F cp4 epsps C-64 cry1A.105 cry2Ab2 cp4 epsps C-65 cry1A.105 cry1F cp4 epsps C-66 cry2Ab2 cry1F cp4 epsps C-67 cry1Ac cry1A.105 cry2Ab2 cp4 epsps C-68 cry1F cry1A.105 cry2Ab2 cp4 epsps C-69 cry1Ac cry1F cry2Ab2 cp4 epsps C-70 cry1Ac cry1A.105 cry1F cp4 epsps C-71 cry1Ac mepsps C-72 cry1A.105 mepsps C-73 cry2Ab2 mepsps C-74 cry1F mepsps C-75 cry1Ac cry1A.105 mepsps C-76 cry1Ac cry2Ab2 mepsps C-77 cry1Ac cry1F mepsps C-78 cry1A.105 cry2Ab2 mepsps C-79 cry1A.105 cry1F mepsps C-80 cry2Ab2 cry1F mepsps C-81 cry1Ac cry1A.105 cry2Ab2 mepsps C-82 cry1F cry1A.105 cry2Ab2 mepsps C-83 cry1Ac cry1F cry2Ab2 mepsps C-84 cry1Ac cry1A.105 cry1F mepsps - In view of the above preferences regarding pests and plants, the following embodiments of the use or method of the invention comprising the application of the mixture of the invention are particularly preferred.
- In one preferred embodiment of the invention, the present invention relates to the use or method comprising the application of the mixture of the invention as defined above, wherein the pests are selected from the group consisting of Anticarsia gemmatalis, Chrysodeixis includens (=Pseudoplusia includens), Helicoverpa armigera (=Heliothis armigera), Spodoptera frugiperda, Spodoptera eridania, Spodoptera cosmioides, and combinations thereof, and the plant is a soybean plant, which has been modified by mutagenesis or genetic engineering, and is preferably selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Anticarsia gemmatalis and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Chrysodeixis includens (=Pseudoplusia includens) and the plant is a soybean plant selected from the soybean plants A325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Helicoverpa armigera (=Heliothis armigera) and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Spodoptera frugiperda and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Spodoptera eridania and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Spodoptera cosmioides and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- As already indicated above, the present invention also relates to certain uses and methods comprising the application of the carboxamide compound I selected from compound i) of formula (I), compound ii) of formula (Ia) and mixtures comprising the carboxamide compounds i) and ii).
- The following remarks as to preferred embodiments of these uses or methods are to be understood as preferred on their own as well as preferably in combination with each other.
- In one aspect, the present invention relates to the use of the carboxamide compound i) of formula (I) in pesticidally effective amounts for protecting a soybean plant, the plant propagation material thereof, or its locus of growth, against the attack or infestation by pests selected from the group consisting of Anticarsia gemmatalis, Chrysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera eridania, Spodoptera frugiperda, and combinations thereof.
- In another aspect, the present invention relates to the use of the carboxamide compound ii) of formula (Ia) in pesticidally effective amounts for protecting a soybean plant, the plant propagation material thereof, or its locus of growth, against the attack or infestation by pests selected from the group consisting of Anticarsia gemmatalis, Chrysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera eridania, Spodoptera frugiperda, and combinations thereof.
- In another aspect, the present invention relates to the use of pesticidally effective amounts of mixtures comprising the carboxamide compounds i) and ii) for protecting a soybean plant, the plant propagation material thereof, or its locus of growth, against the attack or infestation by pests selected from the group consisting of Anticarsia gemmatalis, Chlysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera eridania, Spodoptera frugiperda, and combinations thereof.
- In another aspect, the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of the carboxamide compound i) of formula (I) to a soybean plant, the plant propagation material thereof, or its locus of growth; the pests or their food supply, habitat or breeding grounds, wherein the pests are selected from the group consisting of Anticarsia gemmatalis, Chlysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera eridania, Spodoptera frugiperda, and combinations thereof.
- In still another aspect, the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of the carboxamide compound ii) of formula (Ia) to a soybean plant, the plant propagation material thereof, or its locus of growth; the pests or their food supply, habitat or breeding grounds, wherein the pests are selected from the group consisting of Anticarsia gemmatalis, Chrysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera eridania, Spodoptera frugiperda, and combinations thereof.
- In still another aspect, the present invention relates to a method for controlling pests, which method comprises the application of a pesticidally effective amount of a mixture comprising the carboxamide compounds i) and ii) to a soybean plant, the plant propagation material thereof, or its locus of growth; the pests or their food supply, habitat or breeding grounds, wherein the pests are selected from the group consisting of Anticarsia gemmatalis, Chrysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera eridania, Spodoptera frugiperda, and combinations thereof.
- In a preferred embodiment of the above use or method comprising the application of the carboxamide compound i) of formula (I) the pests are selected from the group consisting of Anticarsia gemmatalis, Chrysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera frugiperda, and combinations thereof.
- For example, the use or method comprising the application of the carboxamide compound I, preferably compound i) of formula (I) may be preferred for pests, which are selected from the group consisting of Anticarsia gemmatalis, Chlysodeixis includens (=Pseudoplusia includens), and a combination thereof.
- In another preferred embodiment, the pests are Anticarsia gemmatalis.
- In another preferred embodiment, the pests are Chrysodeixis includens (=Pseudoplusia includens).
- In another preferred embodiment, the pests are Spodoptera frugiperda.
- In another preferred embodiment, the pests are Spodoptera eridania.
- In another preferred embodiment, the pests are Spodoptera cosmioides.
- In another embodiment of the above use or method comprising the application of the carboxamide compound ii) of formula (Ia) or of a mixture comprising the carboxamide compounds i) and ii), the pests are selected from the group consisting of Anticarsia gemmatalis, Chrysodeixis includens (=Pseudoplusia includens), Spodoptera cosmioides, Spodoptera frugiperda, and combinations thereof.
- As outlined above, the above mentioned pests are of particular relevance in connection with soybean plants.
- In one preferred embodiment of the above use or method comprising the application of the carboxamide compound i) of formula (I), the soybean plant is a soybean plant, which has been modified by conventional breeding, i.e. a soybean plant, which has not been modified by mutagenesis or genetic engineering.
- In another embodiment of the above use or method comprising the application of the carboxamide compound ii) of formula (Ia) or of a mixture comprising the carboxamide compounds i) and ii), the soybean plant is a soybean plant, which has been modified by conventional breeding, i.e. a soybean plant, which has not been modified by mutagenesis or genetic engineering.
- In another preferred embodiment of the above use or method comprising the application of the carboxamide compound i) of formula (I), the soybean plant is a soybean plant, which has been modified by mutagenesis or genetic engineering.
- In another embodiment of the above use or method comprising the application of the carboxamide compound ii) of formula (Ia) or of a mixture comprising the carboxamide compounds i) and ii), the soybean plant is a soybean plant, which has been modified by mutagenesis or genetic engineering.
- Preferred soybean plants, which have been modified by mutagenesis or genetic engineering, have been defined above.
- Preferably, the soybean plant has been modified by genetic engineering and exhibits insect resistance, in particular lepidopteran resistance, wherein insect resistance is provided by one or more genes selected from the group consisting of cry1Ac, cry1F, cry1A.105, cry2Ab2, and combinations thereof, preferably by cry1Ac, cry1F, or a combination thereof, and more preferably by cry1Ac. Optionally, the soybean plant exhibits at least one further trait, preferably herbicide tolerance, e.g. glyphosate tolerance or glufosinate tolerance, wherein herbicide tolerance is preferably provided by one or more genes selected from the group consisting of pat, bar, 2mepsps, cp4 epsps, and mepsps.
- Particularly preferred soybean plants include soybean plants, which are selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84 as defined above.
- In view of the above preferences regarding pests and plants, the following embodiments of the use or method of the invention comprising the application of the carboxamide compound I, preferably compound i) of formula (I) are particularly preferred.
- In a preferred embodiment of the invention, the present invention relates to a use or method as defined above, wherein the pests are selected from the group consisting of Anticarsia gemmatalis, Chrysodeixis includens (=Pseudoplusia includens), Spodoptera frugiperda, Spodoptera eridania, Spodoptera cosmioides, and combinations thereof, and the plant is a soybean plant, which has been modified by mutagenesis or genetic engineering, and is preferably selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Anticarsia gemmatalis and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Chrysodeixis includens (=Pseudoplusia includens) and the plant is a soybean plant selected from the soybean plants A325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Spodoptera frugiperda and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Spodoptera eridania and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- In one particularly preferred embodiment, the pests are Spodoptera cosmioides and the plant is a soybean plant selected from the soybean plants A-325 to A-355, B-1 to B-4, or C-1 to C-84.
- Mixtures
- The remarks as to preferred embodiments of the carboxamide compound I, preferably compound i) of formula (I) are to be understood as preferred on their own as well as in combination with other pesticidal active ingredients and also in combination with the preferred embodiments regarding uses and methods comprising the application of the carboxamide compound I, preferably compound i) of formula (I) as defined herein, and in combination with preferred embodiments regarding the agrochemical composition as defined herein.
- In one embodiment, the mixture of the invention is a binary mixture, i.e. a mixture, which does not comprise any further pesticidal compounds apart from the carboxamide compound i) of formula (I) and one other pesticidal active ingredient.
- In another embodiment, the mixture of the invention is a binary mixture, i.e. a mixture, which does not comprise any further pesticidal compounds apart from the carboxamide compound ii) of formula (Ia) and one other pesticidal active ingredient.
- In one embodiment, the mixture of the invention is a mixture, which does not comprise any further pesticidal compounds apart from the mixture comprising the carboxamide compounds i) and ii) and one other pesticidal active ingredient.
- In another embodiment, the mixture of the present invention comprises a ternary mixture comprising the carboxamide compound i) of formula (I), a second pesticidal compound as component II and a third pesticidal compound as component III, wherein the pesticidal compounds II and III are both an insecticide or both a fungicide or one an insecticide and the other a fungicide.
- In another embodiment, the mixture of the present invention comprises a ternary mixture comprising the carboxamide compound ii) of formula (Ia), a second pesticidal compound as component II and a third pesticidal compound as component III, wherein the pesticidal compounds II and III are both an insecticide or both a fungicide or one an insecticide and the other a fungicide.
- In still another embodiment, the mixture of the present invention comprises a mixture comprising the carboxamides compounds i) and ii), another pesticidal compound as component II and still another pesticidal compound as component III, wherein the pesticidal compounds II and III are both an insecticide or both a fungicide or one an insecticide and the other a fungicide. In a further embodiment, the mixture of the present invention comprises a multinary mixture of the carboxamide compound i) of formula (I) and three or four or more other pesticidal compounds as components II, III, IV or V etc., wherein these further pesticidal compounds are insecticides and/or fungicides.
- In a further embodiment, the mixture of the present invention comprises a multinary mixture of the carboxamide compound ii) of formula (Ia) and three or four or more other pesticidal compounds as components II, III, IV or V etc., wherein these further pesticidal compounds are insecticides and/or fungicides.
- In a further embodiment, the mixture of the present invention comprises a multinary mixture of the carboxamide compounds i), ii) and three or four or more other pesticidal compounds as components II, III, IV or V etc., wherein these further pesticidal compounds are insecticides and/or fungicides.
- The present invention also relates to an agrochemical composition, which comprises a mixture according to the present invention and an auxiliary.
- Suitable formulations and auxiliaries are defined further below.
- Mixing partners can be selected from pesticides, in particular insecticides, nematicides, and acaricides, fungicides, herbicides, plant growth regulators, fertilizers, and the like.
- Preferred mixing partners are insecticides, nematicides and fungicides.
- The following list M of pesticides, grouped and numbered according the Mode of Action Classification of the Insecticide Resistance Action Committee (IRAC), together with which the carboxamide compound i) of formula (I) can be used for the methods of the present invention, and with which potential synergistic effects might be produced between the combination of the active ingredients or with the active ingredients and the cultivated plants, is intended to illustrate the possible combinations, but not to impose any limitation:
- M.1 Acetylcholine esterase (AChE) inhibitors from the class of: M.1A carbamates, for example aldicarb, alanycarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, trimethacarb, XMC, xylylcarb and triazamate; or from the class of M.1B organophosphates, for example acephate, azamethiphos, azinphos-ethyl, azinphosmethyl, cadusafos, chlorethoxyfos, chlorfenvinphos, chlormephos, chlorpyrifos, chlorpyrifos-methyl, coumaphos, cyanophos, demeton-S-methyl, diazinon, dichlorvos/DDVP, dicrotophos, dimethoate, dimethylvinphos, disulfoton, EPN, ethion, ethoprophos, famphur, fenamiphos, fenitrothion, fenthion, fosthiazate, heptenophos, imicyafos, isofenphos, isopropyl O-(methoxyaminothio-phosphoryl) salicylate, isoxathion, malathion, mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion, parathion-methyl, phenthoate, phorate, phosalone, phosmet, phosphamidon, phoxim, pirimiphos-methyl, profenofos, propetamphos, prothiofos, pyraclofos, pyridaphenthion, quinalphos, sulfotep, tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon and vamidothion;
- M.2. GABA-gated chloride channel antagonists such as: M.2A cyclodiene organochlorine compounds, as for example endosulfan or chlordane; or M.2B fiproles (phenylpyrazoles), as for example ethiprole, fipronil, flufiprole, pyrafluprole and pyriprole;
- M.3 Sodium channel modulators from the class of M.3A pyrethroids, for example acrinathrin, allethrin, d-cis-trans allethrin, d-trans allethrin, bifenthrin, bioallethrin, bioallethrin S-cylclopentenyl, bioresmethrin, cycloprothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, empenthrin, esfenvalerate, etofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, tau-fluvalinate, halfenprox, heptafluthrin, imiprothrin, meperfluthrin, metofluthrin, momfluorothrin, permethrin, phenothrin, prallethrin, profluthrin, pyrethrin (pyrethrum), resmethrin, silafluofen, tefluthrin, tetramethylfluthrin, tetramethrin, tralomethrin and transfluthrin; or M.3B sodium channel modulators such as DDT or methoxychlor;
- M.4 Nicotinic acetylcholine receptor agonists (nAChR) from the class of M.4A neonicotinoids, for example acetamiprid, clothianidin, cycloxaprid, dinotefuran, imidacloprid, nitenpyram, thiacloprid and thiamethoxam; or the compounds M.4A.2: (2E+1-[(6-Chloropyridin-3-yl)methyl]-N′-nitro-2-pentylidenehydrazinecarboxinnidamide; or M4.A.3: 1-[(6-Chloropyridin-3-yl)methyl]-7-methyl-8-nitro-5-propoxy-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridine; or from the class M.4B nicotine;
- M.5 Nicotinic acetylcholine receptor allosteric activators from the class of spinosyns, for example spinosad or spinetoram;
- M.6 Chloride channel activators from the class of avermectins and milbemycins, for example abamectin, emamectin benzoate, ivermectin, lepimectin or milbemectin;
- M.7 Juvenile hormone mimics, such as M.7A juvenile hormone analogues as hydroprene, kinoprene and methoprene; or others as M.7B fenoxycarb or M.7C pyriproxyfen;
- M.8 miscellaneous non-specific (multi-site) inhibitors, for example M.8A alkyl halides as methyl bromide and other alkyl halides, or M.8B chloropicrin, or M.8C sulfuryl fluoride, or M.8D borax, or M.8E tartar emetic;
- M.9 Selective homopteran feeding blockers, for example M.9B pymetrozine, or M.9C flonicamid;
- M.10 Mite growth inhibitors, for example M.10A clofentezine, hexythiazox and diflovidazin, or M.10 B etoxazole;
- M.11 Microbial disruptors of insect midgut membranes, for example bacillus thuringiensis or bacillus sphaericus and the insecticdal proteins they produce such as bacillus thuringiensis subsp. israelensis, bacillus sphaericus, bacillus thuringiensis subsp. aizawai, bacillus thuringiensis subsp. kurstaki and bacillus thuringiensis subsp. tenebrionis, or the Bt crop proteins: Cry1Ab, Cry1Ac, Cry1Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb and Cry34/35Ab1;
- M.12 Inhibitors of mitochondrial ATP synthase, for example M.12A diafenthiuron, or M.12B organotin miticides such as azocyclotin, cyhexatin or fenbutatin oxide, or M.12C propargite, or M.12D tetradifon;
- M.13 Uncouplers of oxidative phosphorylation via disruption of the proton gradient, for example chlorfenapyr, DNOC or sulfluramid;
- M.14 Nicotinic acetylcholine receptor (nAChR) channel blockers, for example nereistoxin analogues as bensultap, cartap hydrochloride, thiocyclam or thiosultap sodium;
- M.15 Inhibitors of the chitin biosynthesis type 0, such as benzoylureas as for example bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, or triflumuron;
- M.16 Inhibitors of the chitin biosynthesis type 1, as for example buprofezin;
- M.17 Moulting disruptors, Dipteran, as for example cyromazine;
- M.18 Ecdyson receptor agonists such as diacylhydrazines, for example methoxyfenozide, tebufenozide, halofenozide, fufenozide or chromafenozide;
- M.19 Octopamin receptor agonists, as for example amitraz;
- M.20 Mitochondrial complex III electron transport inhibitors, for example M.20A hydramethylnon, or M.206 acequinocyl, or M.20C fluacrypyrim;
- M.21 Mitochondrial complex I electron transport inhibitors, for example M.21A METI acaricides and insecticides such as fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad or tolfenpyrad, or M.216 rotenone;
- M.22 Voltage-dependent sodium channel blockers, for example M.22A indoxacarb, or M.22B metaflumizone, or M.22B.1: 2-[2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]¬ethylidene]-N-[4-(difluoromethoxy)phenyl]-hydrazinecarboxamide or M.22B.2: N-(3-Chloro-2-methylphenyl)-2-[(4-chlorophenyl)[4-[methyl(methylsulfonyl)amino]phenyl]¬methylene]-hydrazinecarboxamide;
- M.23 Inhibitors of the of acetyl CoA carboxylase, such as Tetronic and Tetramic acid derivatives, for example spirodiclofen, spiromesifen or spirotetramat;
- M.24 Mitochondrial complex IV electron transport inhibitors, for example M.24A phosphine such as aluminium phosphide, calcium phosphide, phosphine or zinc phosphide, or M.246 cyanide;
- M.25 Mitochondrial complex II electron transport inhibitors, such as beta-ketonitrile derivatives, for example cyenopyrafen or cyflumetofen;
- M.28 Ryanodine receptor-modulators from the class of diamides, as for example flubendiamide, chlorantraniliprole (Rynaxypyr®), cyantraniliprole (Cyazypyr®), tetraniliprole, or the phthalamide compounds M.28.1: (R)-3-Chlor-N1-{2-methyl-4-[1,2,2,2 tetrafluor-1-(trifluormethyl)ethyl]phenyl}-N2-(1-methyl-2-methylsulfonylethyl)phthalannid and M.28.2: (S)-3-Chlor-N1-{2-methyl-4-[1,2,2,2 tetrafluor-1-(trifluormethyl)ethyl]phenyl}-N2-(1-methyl-2-methylsulfonylethyl)phthalamid, or the compound M.28.3: 3-bromo-N-{2-bromo-4-chloro-6-[(1-cyclopropylethyl)carbamoyl]phenyl}-1-(3-chlorpyridin-2-yl)-1H-pyrazole-5-carboxamide (proposed ISO name: cyclaniliprole), or the compound M.28.4: methyl-2-[3,5-dibromo-2-({[3-bromo-1-(3-chlorpyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)benzoyl]-1,2-dimethylhydrazinecarboxylate; or a compound selected from M.28.5a) to M.28.5d) and M.28.5h) to M.28.5l): M.28.5a) N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5b) N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5c) N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5d) N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5h) N-[4,6-dibromo-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5i) N-[2-(5-Amino-1,3,4-thiadiazol-2-yl)-4-chloro-6-methylphenyl]-3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide; M.28.5j) 3-Chloro-1-(3-chloro-2-pyridinyl)-N-[2,4-dichloro-6-[[(1-cyano-1-methylethyl)amino]carbonyl]phenyl]-1H-pyrazole-5-carboxamide; M.28.5k) 3-Bromo-N-[2,4-dichloro-6-(methylcarbamoyl)phenyl]-1-(3,5-dichloro-2-pyridyl)-1H-pyrazole-5-carboxamide; M.28.5l) N-[4-Chloro-2-[[(1,1-dimethylethyl)amino]carbonyl]-6-methylphenyl]-1-(3-chloro-2-pyridinyl)-3-(fluoromethoxy)-1H-pyrazole-5-carboxamide;
- or M.28.6: cyhalodiamide; or
- M.29: insecticidal active compounds of unknown or uncertain mode of action, as for example afidopyropen, afoxolaner, azadirachtin, amidoflumet, benzoximate, bifenazate, bromopropylate, chinomethionat, cryolite, dicloromezotiaz, dicofol, flufenerim, flometoquin, fluensulfone, fluhexafon, fluopyram, flupyradifurone, fluralaner, metoxadiazone, piperonyl butoxide, pyflubumide, pyridalyl, pyrifluquinazon, sulfoxaflor, tioxazafen, triflunnezopyrinn, or the compounds
- M.29.3: 11-(4-chloro-2,6-dimethylphenyl)-12-hydroxy-1,4-dioxa-9-azadispiro[4.2.4.2]-tetradec-11-en-10-one, or the compound
- M.29.4: 3-(4′-fluoro-2,4-dimethylbiphenyl-3-yl)-4-hydroxy-8-oxa-1-azaspiro[4.5]dec-3-en-2-one, or the compound
- M.29.5: 1-[2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-amine, or actives on basis of bacillus firmus (Votivo, 1-1582); or
- a compound selected from the group of M.29.6, wherein the compound is selected from M.29.6a) to M.29.6k): M.29.6a) (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6b) (E/Z)—N-[1-[(6-chloro-5-fluoro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6c) (E/Z)-2,2,2-trifluoro-N-[1-[(6-fluoro-3-pyridyl)methyl]-2-pyridylidene]acetamide; M.29.6d) (E/Z)—N-[1-[(6-bromo-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6e) (E/Z)—N-[1-[1-(6-chloro-3-pyridyl)ethyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6f) (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2-difluoroacetamide; M.29.6g) (E/Z)-2-chloro-N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2-difluoroacetamide; M.29.6h) (E/Z)—N-[1-[(2-chloropyrimidin-5-yl)methyl]-2-pyridylidene]-2,2,2-trifluoro-acetamide; M.29.6i) (E/Z)—N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,3,3,3-pentafluoro-propanamide); M.29.6j) N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-thioacetamide; or M.29.6k) N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoro-N′-isopropyl-acetamidine; or the compounds
- M.29.8: fluazaindolizine; or the compounds
- M.29.9.a): 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]-2-methyl-N-(1-oxothietan-3-yl)benzamide; or M.29.9.b): fluxametamide; or
- M.29.10: 5-[3-[2,6-dichloro-4-(3,3-dichloroallyloxy)phenoxy]propoxy]-1H-pyrazole; or
- a compound selected from the group of M.29.11, wherein the compound is selected from M.29.11b) to M.29.11p): M.29.11.b) 3-(benzoylmethylamino)-N-[2-bromo-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]-6-(trifluoromethyl)phenyl]-2-fluoro-benzamide; M.29.11.c) 3-(benzoylmethylamino)-2-fluoro-N-[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]-benzamide; M.29.11.d) N-[3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-N-methyl-benzamide; M.29.11.e) N-[3-[[[2-bromo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]-2-fluorophenyl]-4-fluoro-N-methyl-benzamide; M.29.11.f) 4-fluoro-N-[2-fluoro-3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)¬ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-N-methyl-benzamide; M.29.11.g) 3-fluoro-N-[2-fluoro-3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)¬ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-N-methyl-benzamide; M.29.11.h) 2-chloro-N-[3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-3-pyridinecarboxamide; M.29.11.i) 4-cyano-N-[2-cyano-5-[[2,6-dibromo-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]carbamoyl]phenyl]-2-methyl-benzamide; M.29.11.j) 4-cyano-3-[(4-cyano-2-methylbenzoyl)amino]-N-[2,6-dichloro-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)-propyl]phenyl]-2-fluoro-benzamide; M.29.11.k) N-[5-[[2-chloro-6-cyano-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide; M.29.11.l) N-[5-[[2-bromo-6-chloro-4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide; M.29.11.m) N-[5-[[2-bromo-6-chloro-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide; M.29.11.n) 4-cyano-N-[2-cyano-5-[[2,6-dichloro-4-[1,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]carbamoyl]phenyl]-2-methyl-benzamide; M.29.11.o) 4-cyano-N-[2-cyano-5-[[2,6-dichloro-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]carbamoyl]¬phenyl]-2-methyl-benzamide; M.29.11.p) N-[5-[[2-bromo-6-chloro-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide; or
- a compound selected from the group of M.29.12, wherein the compound is selected from M.29.12a) to M.29.12m): M.29.12.a) 2-(1,3-Dioxan-2-yl)-6-[2-(3-pyridinyl)-5-thiazolyl]-pyridine; M.29.12.b) 2-[6-[2-(5-Fluoro-3-pyridinyl)-5-thiazolyl]-2-pyridinyl]-pyrimidine; M.29.12.c) 2-[6-[2-(3-Pyridinyl)-5-thiazolyl]-2-pyridinyl]-pyrimidine; M.29.12.d) N-Methylsulfonyl-6-[2-(3-pyridyl)thiazol-5-yl]pyridine-2-carboxamide; M.29.12.e) N-Methylsulfonyl-6-[2-(3-pyridyl)thiazol-5-yl]pyridine-2-carboxamide; M.29.12.f) N-Ethyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide; M.29.12.g) N-Methyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide; M.29.12.h) N,2-Dimethyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide; M.29.12.i) N-Ethyl-2-methyl-N-[4-methyl-2-(3-pyridyl)thiazol-5-yl]-3-methylthio-propanamide; M.29.12.j) N-[4-Chloro-2-(3-pyridyl)thiazol-5-yl]-N-ethyl-2-methyl-3-methylthio-propanamide; M.29.12.k) N-[4-Chloro-2-(3-pyridyl)thiazol-5-yl]-N,2-dimethyl-3-M.29.12.1) N-[4-Chloro-2-(3-pyridyl)thiazol-5-yl]-N-methyl-3-methylthio-propanamide; M.29.12.m) N-[4-Chloro-2-(3-pyridyl)thiazol-5-yl]-N-ethyl-3-methylthio-propanamide; or the compounds
- M.29.14a) 1-[(6-Chloro-3-pyridinyl)methyl]-1,2,3,5,6,7-hexahydro-5-methoxy-7-methyl-8-nitro-imidazo[1,2-a]pyridine; or M.29.14b) 1-[(6-Chloropyridin-3-yl)methyl]-7-methyl-8-nitro-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridin-5-ol; or the compounds
- M.29.16a) 1-isopropyl-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; or M.29.16b) 1-(1,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16c) N,5-dimethyl-N-pyridazin-4-yl-1-(2,2,2-trifluoro-1-methyl-ethyl)pyrazole-4-carboxamide; M.29.16d) 1-[1-(1-cyanocyclopropyl)ethyl]-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16e) N-ethyl-1-(2-fluoro-1-methyl-propyl)-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16f) 1-(1,2-dimethylpropyl)-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16g) 1-[1-(1-cyanocyclopropyl)ethyl]-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16h) N-methyl-1-(2-fluoro-1-methyl-propyl]-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M.29.16i) 1-(4,4-difluorocyclohexyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; or M.29.16j) 1-(4,4-difluorocyclohexyl)-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide, or
- M.29.17 a compound selected from the compounds M.29.17a) to M.29.17j): M.29.17a) N-(1-methylethyl)-2-(3-pyridinyl)-2H-indazole-4-carboxamide; M.29.17b) N-cyclopropyl-2-(3-pyridinyl)-2H-indazole-4-carboxamide; M.29.17c) N-cyclohexyl-2-(3-pyridinyl)-2H-indazole-4-carboxamide; M.29.17d) 2-(3-pyridinyl)-N-(2,2,2-trifluoroethyl)-2H-indazole-4-carboxamide; M.29.17e) 2-(3-pyridinyl)-N-[(tetrahydro-2-furanyl)methyl]-2H-indazole-5-carboxamide; M.29.17f) methyl 2-[[2-(3-pyridinyl)-2H-indazol-5-yl]carbonyl]hydrazinecarboxylate; M.29.17g) N-[(2,2-difluorocyclopropyl)methyl]-2-(3-pyridinyl)-2H-indazole-5-carboxamide; M.29.17h) N-(2,2-difluoropropyl)-2-(3-pyridinyl)-2H-indazole-5-carboxamide; M.29.17i) 2-(3-pyridinyl)-N-(2-pyrimidinylmethyl)-2H-indazole-5-carboxamide; M.29.17j) N-[(5-methyl-2-pyrazinyl)methyl]-2-(3-pyridinyl)-2H-indazole-5-carboxamide, or
- M.29.18 a compound selected from the compounds M.29.18a) to M.29.18d): M.29.18a) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropylsulfanyl)propanamide; M.29.18b) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropylsulfinyl)propanamide; M.29.18c) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-3-[(2,2-difluorocyclopropyl)methylsulfanyl]-N-ethyl-propanamide; M.29.18d) N-[3-chloro-1-(3-pyridyl)pyrazol-4-yl]-3-[(2,2-difluorocyclopropyl)methylsulfinyl]-N-ethyl-propanamide; or the compound
- M.29.19 sarolaner, or the compound
- M.29.20 lotilaner.
- The commercially available compounds of the group M listed above may be found in The Pesticide Manual, 16th Edition, C. MacBean, British Crop Protection Council (2013) among other publications. The online Pesticide Manual is updated regularly and is accessible through http://bcpcdata.conn/pesticide-manual.html.
- Another online data base for pesticides providing the ISO common names is http://www.alanwood.net/pesticides.
- The M.4 neonicotinoid cycloxaprid is known from WO2010/069266 and WO2011/069456, the neonicotinoid M.4A.2, sometimes also to be named as guadipyr, is known from WO2013/003977, and the neonicotinoid M.4A.3 (approved as paichongding in China) is known from WO2007/101369. The metaflumizone analogue M.22B.1 is described in CN10171577 and the analogue M.22B.2 in CN102126994. The phthalamides M.28.1 and M.28.2 are both known from WO2007/101540. The anthranilamide M.28.3 is described in WO2005/077934. The hydrazide compound M.28.4 is described in WO2007/043677. The anthranilamides M.28.5a) to M.28.5d) and M.28.5h) are described in WO 2007/006670, WO2013/024009 and WO2013/024010, the anthranilamide M.28.5i) is described in WO2011/085575, M.28.5j) in WO2008/134969, M.28.5k) in US2011/046186 and M.28.5l) in WO2012/034403. The diamide compound M.28.6 can be found in WO2012/034472. The spiroketal-substituted cyclic ketoenol derivative M.29.3 is known from WO2006/089633 and the biphenyl-substituted spirocyclic ketoenol derivative M.29.4 from WO2008/067911. The triazoylphenylsulfide M.29.5 is described in WO2006/043635, and biological control agents on the basis of bacillus firmus are described in WO2009/124707. The compounds M.29.6a) to M.29.6i) listed under M.29.6 are described in WO2012/029672, and M.29.6j) and M.29.6k) in WO2013/129688. The nematicide M.29.8 is known from WO2013/055584. The isoxazoline M.29.9.a) is described in WO2013/050317. The isoxazoline M.29.9.b) is described in WO2014/126208. The pyridalyl-type analogue M.29.10 is known from WO2010/060379. The carboxamides M.29.11.b) to M.29.11.h) are described in WO2010/018714, and the carboxamides M.29.11i) to M.29.11.p) in WO2010/127926. The pyridylthiazoles M.29.12.a) to M.29.12.c) are known from WO2010/006713, M.29.12.d) and M.29.12.e) are known from WO2012/000896, and M.29.12.f) to M.29.12.m) from WO2010/129497. The compounds M.29.14a) and M.29.14b) are known from WO2007/101369. The pyrazoles M.29.16.a) to M.29.16h) are described in WO2010/034737, WO2012/084670, and WO2012/143317, respectively, and the pyrazoles M.29.16i) and M.29.16j) are described in U.S. 61/891,437. The pyridinylindazoles M.29.17a) to M.29.17.j) are described in WO2015/038503. The pyridylpyrazoles M.29.18a) to M.29.18d) are described in US2014/0213448. The isoxazoline M.29.19 is described in WO2014/036056. The isoxazoline M.29.20 is known from WO2014/090918.
- In another embodiment of the invention, the carboxamide compound ii) of formula (Ia) and the pesticides of the above list M can be used together for the methods of the present invention.
- In still another embodiment of the invention, the mixture comprising the carboxamide compounds i) and ii) and the pesticides of the above list M can be used together for the methods of the present invention.
- The following list of fungicides, in conjunction with which the carboxamide compound i) of formula (I) can be used, is intended to illustrate the possible combinations but does not limit them:
- A) Respiration Inhibitors
-
- Inhibitors of complex III at Qo site (e. g. strobilurins): azoxystrobin (A.1.1), coumeth¬oxystrobin (A.1.2), coumoxystrobin (A.1.3), dimoxystrobin (A.1.4), enestroburin (A.1.5), fenaminstrobin (A.1.6), fenoxy¬strobin/flufenoxystrobin (A.1.7), fluoxastro¬bin (A.1.8), kresoxim-methyl (A.1.9), mandestrobin (A.1.10), meto¬minostrobin (A.1.11), orysastrobin (A.1.12), picoxy¬.strobin (A.1.13), pyraclostrobin (A.1.14), pyrametostrobin (A.1.15), pyraoxystrobin (A.1.16), tri-floxystrobin (A.1.17), 2 (2-(3-(2,6-di¬ichlorophenyl)-1-methyl-allylidene≳aminooxy¬methyl)-phenyl)-2-methoxyimino-N methyl-acetamide (A.1.18), pyribencarb (A.1.19), triclopyricarb/chlorodin¬carb (A.1.20), famoxadone (A.1.21), fenamidone (A.1.21), methyl-N-[2-[(1,4-dimethyl-5-phenyl-pyrazol-3-yl)oxylmethyl]phenyl]-N-methoxy-carbamate (A.1.22), 1-[3-chloro-2-[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxymethyl]phenyl]-4-methyl-tetrazol-5-one (A.1.23), 1-[3-bromo-2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-4-methyl-tetrazol-5-one (A.1.24), 1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-methyl-phenyl]-4-methyl-tetrazol-5-one (A.1.25), 1-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]-3-fluoro-phenyl]-4-methyl-tetrazol-5-one (A.1.26), 1-[2-[[1-(2,4-dichlorophenyl)pyrazol-3-yl]oxymethyl]-3-fluoro-phenyl]-4-methyl-tetrazol-5-one (A.1.27), 1-[2-[[4-(4-chlorophenyl)thiazol-2-yl]oxymethyl]-3-methyl-phenyl]-4-methyl-tetrazol-5-one (A.1.28), 1-[3-chloro-2-[[4-(p-tolyl)thiazol-2-yl]-oxymethyl]phenyl]-4-methyl-tetrazol-5-one (A.1.29), 1-[3-cyclopropyl-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]methyl]phenyl]-4-methyl-tetrazol-5-one (A.1.30), 1-[3-(difluoromethoxy)-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]methyl]phenyl]-4-methyl-tetrazol-5-one (A.1.31), 1-methyl-4-[3-methyl-2-[[2-methyl-4-(1-methylpyrazol-3-yl)phenoxy]methyl]phenyl]tetrazol-5-one (A.1.32), 1-methyl-4-[3-methyl-2-[[1-[3-(trifluoromethyl)phenyl]-ethylideneamino]oxymethyl]phenyl]tetrazol-5-one (A.1.33), (Z,2E)-5-[1-(2,4-dichloro-phenyl)pyrazol-3-yl]-oxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide (A.1.34), (Z,2E)-5-[1-(4-chlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino-N,3-dimethyl-pent-3-enamide (A.1.35), pyriminostrobin (A.1.36), bifujunzhi (A.1.37), 2-(ortho-((2,5-dimethylphenyl-oxymethylen)phenyl)-3-methoxy-acrylic acid methylester (A.1.38);
- inhibitors of complex III at Qi site: cyazofamid (A.2.1), amisulbrom (A.2.2) [(6S,7R,8R)-8-benzyl-3-[(3-hydroxy-4-methoxy-pyridine-2-carbonyl)amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylpropanoate (A.2.3), [2-[[(7R,8R,9S)-7-benzyl-9-methyl-8-(2-methylpropanoyloxy)-2,6-dioxo-1,5-dioxonan-3-yl]carbamoyl]-4-methoxy-3-pyridyl]oxymethyl 2-methylpropanoate (A.2.4), [(6S,7R,8R)-8-benzyl-3-[[4-methoxy-3-(propanoyloxymethoxy)pyridine-2-carbonyl]amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl] 2-methylpropanoate (A.2.5);
- inhibitors of complex II: benodanil (A.3.1), benzovindiflupyr (A.3.2), bixafen (A.3.3), boscalid (A.3.4), carboxin (A.3.5), fenfuram (A.3.6), fluopyram (A.3.7), flutolanil (A.3.8), fluxapyroxad (A.3.9), furannetpyr (A.3.10), isofetamid (A.3.11), isopyrazam (A.3.12), mepronil (A.3.13), oxycarboxin (A.3.14), penflufen (A.3.15), penthiopyrad (A.3.16), sedaxane (A.3.19), tecloftalam (A.3.20), thifluzamide (A.3.21), 3-(difluoromethyl)-1-methyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.22), 3-(trifluoromethyl)-1-methyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.23), 1,3-dimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.24), 3-(trifluoromethyl)-1,5-dimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.25), 1,3,5-trimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.26), 3-(difluoromethyl)-1,5-dimethyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide (A.3.27), 3-(difluoromethyl)-N-(7-fluoro-1,1,3-trimethyl-indan-4-yl)-1-methyl-pyrazole-4-carboxamide (A.3.28), methyl (E)-2-[2-[(5-cyano-2-methyl-phenoxy)methyl]phenyl]-3-methoxyprop-2-enoate (A.3.30);
- other respiration inhibitors: diflumetorim (A.4.1); nitrophenyl derivates: binapacryl (A.4.2), dinobuton (A.4.3), dinocap (A.4.4), fluazinam (A.4.5), ferimzone (A.4.7); organometal compounds: fentin salts, e. g. fentin-acetate (A.4.8), fentin chloride (A.4.9) or fentin hydroxide (A.4.10); ametoctradin (A.4.11); silthiofam (A.4.12);
- B) Sterol Biosynthesis Inhibitors (SBI Fungicides)
-
- C14 demethylase inhibitors: triazoles: azaconazole (B.1.1), bitertanol (B.1.2), bromuconazole (B.1.3), cyproconazole (B.1.4), difenoconazole (B.1.5), diniconazole (B.1.6), diniconazole-M (B.1.7), epoxiconazole (B.1.8), fenbuconazole (B.1.9), fluquinconazole (B.1.10), flusilazole (B.1.11), flutriafol (B.1.12), hexaconazole (B.1.13), imibenconazole (B.1.14), ipconazole (B.1.15), metconazole (B.1.17), myclobutanil (B.1.18), oxpoconazole (B.1.19), paclobutrazole (B.1.20), penconazole (B.1.21), propiconazole (B.1.22), prothioconazole (B.1.23), simeconazole (B.1.24), tebuconazole (B.1.25), tetraconazole (B.1.26), triadimefon (B.1.27), triadimenol (B.1.28), triticonazole (B.1.29), uniconazole (B.1.30), 1-[rel-(2S,3A)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)-oxiranylmethyl]-5-thiocyanato-1H-[1,2,4]triazole (B.1.31), 2-[rel-(2S;3A)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)-oxiranylmethyl]-2H-[1,2,4]triazole-3-thiol (B.1.32), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)pentan-2-ol (B.1.33), 1-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-cyclopropyl-2-(1,2,4-triazol-1-yl)ethanol (B.1.34), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)butan-2-ol (B.1.35), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)butan-2-ol (B.1.36), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-3-methyl-1-(1,2,4-triazol-1-yl)butan-2-ol (B.1.37), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (B.1.38), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-3-methyl-1-(1,2,4-triazol-1-yl)butan-2-ol (B.1.39), 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)pentan-2-ol (B.1.40), 2-[4-(4-fluorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol (B.1.41), 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)pent-3-yn-2-ol (B.1.42), 2-(chloromethyl)-2-methyl-5-(p-tolylmethyl)-1-(1,2,4-triazol-1-ylmethyl)cyclopentanol (B.1.43); imidazoles: imazalil (B.1.44), pefurazoate (B.1.45), prochloraz (B.1.46), triflumizol (B.1.47); pyrimidines, pyridines and piperazines: fenarimol (B.1.49), pyrifenox (B.1.50), triforine (B.1.51), [3-(4-chloro-2-fluoro-phenyl)-5-(2,4-difluorophenyl)isoxazol-4-yl]-(3-pyridyl)methanol (B.1.52);
- Delta14-reductase inhibitors: aldimorph (B.2.1), dodemorph (B.2.2), dodemorph-acetate (B.2.3), fenpropimorph (B.2.4), tridemorph (B.2.5), fenpropidin (B.2.6), piperalin (B.2.7), spiroxamine (B.2.8);
- Inhibitors of 3-keto reductase: fenhexamid (B.3.1);
- Other Sterol biosynthesis inhibitors: chlorphenonnizole (B.4.1);
- C) Nucleic Acid Synthesis Inhibitors
-
- phenylamides or acyl amino acid fungicides: benalaxyl (C.1.1), benalaxyl-M (C.1.2), kiralaxyl (C.1.3), metalaxyl (C.1.4), metalaxyl-M (C.1.5), ofurace (C.1.6), oxadixyl (C.1.7);
- other nucleic acid synthesis inhibitors: hymexazole (C.2.1), octhilinone (C.2.2), oxolinic acid (C.2.3), bupirimate (C.2.4), 5-fluorocytosine (C.2.5), 5-fluoro-2-(p-tolylmethoxy)pyrimidin-4-amine (C.2.6), 5-fluoro-2-(4-fluorophenylmethoxy)pyrimidin-4-amine (C.2.7), 5-fluoro-2-(4-chlorophenylmethoxy)pyrimidin-4 amine (C.2.8);
- D) Inhibitors of Cell Division and Cytoskeleton
-
- tubulin inhibitors: benomyl (D.1.1), carbendazim (D.1.2), fuberidazole (D1.3), thiabendazole (D.1.4), thiophanate-methyl (D.1.5), 3-chloro-4-(2,6-difluorophenyl)-6-methyl-5-phenyl-pyridazine (D.1.6), 3-chloro-6-methyl-5-phenyl-4-(2,4,6-trifluorophenyl)pyridazine (D.1.7), N-ethyl-2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]butanamide (D.1.8), N-ethyl-2-[(3-ethynyl-8-methyl-6-guinolyl)oxy]-2-methylsulfanyl-acetamide (D.1.9), 2-[(3-ethynyl-8-methyl-6-guinolyl)oxy]-N-(2-fluoroethyl)butanamide (D.1.10), 2-[(3-ethynyl-8-methyl-6-guinolyl)oxy]-N-(2-fluoroethyl)-2-methoxy-acetamide (D.1.11), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-propyl-butanamide (D.1.12), 2-[(3-ethynyl-8-methyl-6-guinolypoxy]-2-methoxy-N-propyl-acetamide (D.1.13), 2-[(3-ethynyl-8-methyl-6-guinolyl)oxy]-2-methylsulfanyl-N-propyl-acetamide (D.1.14), 2-[(3-ethynyl-8-methyl-6-guinolyl)oxy]-N-(2-fluoroethyl)-2-methylsulfanyl-acetamide (D.1.15), 4-(2-bromo-4-fluoro-phenyl)-N-(2-chloro-6-fluoro-phenyl)-2,5-dimethyl-pyrazol-3-amine (D.1.16);
- other cell division inhibitors: diethofencarb (D.2.1), ethaboxam (D.2.2), pencycuron (D.2.3), fluopicolide (D.2.4), zoxamide (D.2.5), metrafenone (D.2.6), pyriofenone (D.2.7); E) Inhibitors of amino acid and protein synthesis
- methionine synthesis inhibitors: cyprodinil (E.1.1), mepanipyrim (E.1.2), pyrimethanil (E.1.3);
- protein synthesis inhibitors: blasticidin-S(E.2.1), kasugamycin (E.2.2), kasugamycin hydrochloride-hydrate (E.2.3), mildiomycin (E.2.4), streptomycin (E.2.5), oxytetracyclin (E.2.6);
- F) Signal Transduction Inhibitors
-
- MAP/histidine kinase inhibitors: fluoroimid (F.1.1), iprodione (F.1.2), procymidone (F.1.3), vinclozolin (F.1.4), fludioxonil (F.1.5);
- G protein inhibitors: quinoxyfen (F.2.1);
- G) Lipid and Membrane Synthesis Inhibitors
-
- Phospholipid biosynthesis inhibitors: edifenphos (G.1.1), iprobenfos (G.1.2), pyrazophos (G.1.3), isoprothiolane (G.1.4);
- lipid peroxidation: dicloran (G.2.1), quintozene (G.2.2), tecnazene (G.2.3), tolclofos-methyl (G.2.4), biphenyl (G.2.5), chloroneb (G.2.6), etridiazole (G.2.7);
- phospholipid biosynthesis and cell wall deposition: dimethomorph (G.3.1), flumorph (G.3.2), mandipropamid (G.3.3), pyrimorph (G.3.4), benthiavalicarb (G.3.5), iprovalicarb (G.3.6), valifenalate (G.3.7);
- compounds affecting cell membrane permeability and fatty acides: propamocarb (G.4.1);
- inhibitors of oxysterol binding protein: oxathiapiprolin (G.5.1), 2-{3-[2-(1-{[3,5-bis(difluoromethyl-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-phenyl methanesulfonate (G.5.2), 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-acetyl}piperidin-4-yl) 1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate (G.5.3), 4-[1-[2-[3-(difluoromethyl)-5-methyl-pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.4), 4-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.5), 4-[1-[2-[3-(difluoromethyl)-5-(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.6), 4-[1-[2-[5-cyclopropyl-3-(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.7), 4-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.8), 4-[1-[2-[5-(difluoromethyl)-3-(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.9), 4-[1-[2-[3,5-bis(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.10), (4-[1-[2-[5-cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-N-tetralin-1-yl-pyridine-2-carboxamide (G.5.11);
- H) Inhibitors with Multi Site Action
-
- inorganic active substances: Bordeaux mixture (H.1.1), copper (H.1.2), copper acetate (H.1.3), copper hydroxide (H.1.4), copper oxychloride (H.1.5), basic copper sulfate (H.1.6), sulfur (H.1.7);
- thio- and dithiocarbamates: ferbam (H.2.1), mancozeb (H.2.2), maneb (H.2.3), metam (H.2.4), metiram (H.2.5), propineb (H.2.6), thiram (H.2.7), zineb (H.2.8), ziram (H.2.9);
- organochlorine compounds: anilazine (H.3.1), chlorothalonil (H.3.2), captafol (H.3.3), captan (H.3.4), folpet (H.3.5), dichlofluanid (H.3.6), dichlorophen (H.3.7), hexachlorobenzene (H.3.8), pentachlorphenole (H.3.9) and its salts, phthalide (H.3.10), tolylfluanid (H.3.11);
- guanidines and others: guanidine (H.4.1), dodine (H.4.2), dodine free base (H.4.3), guazatine (H.4.4), guazatine-acetate (H.4.5), iminoctadine (H.4.6), iminoctadine-triacetate (H.4.7), iminoctadine-tris(albesilate) (H.4.8), dithianon (H.4.9), 2,6-dimethyl-1H,5H[1,4]dithiino[2,3-c:5,6-c′]dipyrrole-1,3,5,7(2H,6H)-tetraone (H.4.10);
- I) Cell Wall Synthesis Inhibitors
-
- inhibitors of glucan synthesis: validamycin (1.1.1), polyoxin B (1.1.2);
- melanin synthesis inhibitors: pyroquilon (1.2.1), tricyclazole (1.2.2), carpropamid (1.2.3), dicyclomet (1.2.4), fenoxanil (1.2.5);
- J) Plant Defence Inducers
-
- acibenzolar-S-methyl (J.1.1), probenazole (J.1.2), isotianil (J.1.3), tiadinil (J.1.4), prohexadione-calcium (J.1.5); phosphonates: fosetyl (J.1.6), fosetyl-aluminum (J.1.7), phosphorous acid and its salts (J.1.8), potassium or sodium bicarbonate (J.1.9);
- K) Unknown Mode of Action
-
- bronopol (K.1.1), chinonnethionat (K.1.2), cyflufenamid (K.1.3), cymoxanil (K.1.4), dazomet (K.1.5), debacarb (K.1.6), diclocymet (K.1.7), diclomezine (K.1.8), difenzoquat (K.1.9), difenzoquat-methylsulfate (K.1.10), diphenylamin (K.1.11), fenitropan (K.1.12), fenpyrazamine (K.1.13), flumetover (K.1.14), flusulfamide (K.1.15), flutianil (K.1.16), harpin (K.1.17), methasulfocarb (K.1.18), nitrapyrin (K.1.19), nitrothal-isopropyl (K.1.20), tolprocarb (K.1.21), oxincopper (K.1.22), proquinazid (K.1.23), tebufloquin (K.1.24), tecloftalam (K.1.25), triazoxide (K.1.26), N′-(4-(4-chloro-3-trifluoromethyl-phenoxy)-2,5-dimethyl-phenyl)-N-ethyl-N-methyl formamidine (K.1.27), N′-(4-(4-fluoro-3-trifluoromethyl-phenoxy)-2,5-dimethyl-phenyl)-N-ethyl-N-methyl formamidine (K.1.28), N′-[4-[[3-[(4-chlorophenyl)methyl]-1,2,4-thiadiazol-5-yl]oxy]-2,5-dimethyl-phenyl]-N-ethyl-N-methyl-formamidine (K.1.29), N′-(5-bromo-6-indan-2-yloxy-2-methyl-3-pyridyl)-N-ethyl-N-methyl-formamidine (K.1.30), N′-[5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methyl-3-pyridyl]-N-ethyl-N-methyl-formamidine (K.1.31), N′-[5-bromo-6-(4-isopropylcyclohexoxy)-2-methyl-3-pyridyl]-N-ethyl-N-methyl-formamidine (K.1.32), N′-[5-bromo-2-methyl-6-(1-phenylethoxy)-3-pyridyl]-N-ethyl-N-methyl-formamidine (K.1.33), N′-(2-methyl-5-trifluoromethyl-4-(3-trimethylsilanyl-propoxy)-phenyl)-N-ethyl-N-methyl formamidine (K.1.34), N′-(5-difluoromethyl-2-methyl-4-(3-trimethylsilanyl-propoxy)-phenyl)-N-ethyl-N-methyl formamidine (K.1.35), 2-(4-chloro-phenyl)-N-[4-(3,4-dimethoxy-phenyl)-isoxazol-5-yl]-2-prop-2-ynyloxy-acetamide (K.1.36), 3-[5-(4-chloro-phenyl)-2,3-dimethyl-isoxazolidin-3-yl]pyridine (pyrisoxazole) (K.1.37), 3-[5-(4-methylphenyl)-2,3-dimethyl-isoxazolidin-3 yl]-pyridine (K.1.38), 5-chloro-1-(4,6-dimethoxy-pyrimidin-2-yl)-2-methyl-1H-benzoimidazole (K.1.39), ethyl (Z)-3-amino-2-cyano-3-phenyl-prop-2-enoate (K.1.40), picarbutrazox (K.1.41), pentyl N-[6-[[(Z)-[(1-methyltetrazol-5-yl)phenyl-methylene]amino]oxymethyl]-2-pyridyl]carbamate (K.1.42), 2-[2-[(7,8-difluoro-2-methyl-3-quinolyloxy]-6-fluoro-phenyl]propan-2-ol (K.1.44), 2-[2-fluoro-6-[(8-fluoro-2-methyl-3-quinolyloxy]phen-yl]propan-2-ol (K.1.45), 3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinolin-1-yl)quinoline (K.1.46), 3-(4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline (K.1.47), 3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline (K.1.48), 9-fluoro-2,2-dimethyl-5-(3-quinolyl)-3H-1,4-benzoxazepine (K.1.49), 2-(6-benzyl-2-pyridyl)quinazoline (K.1.50), 2-[6-(3-fluoro-4-methoxy-phenyl)-5-methyl-2-pyridyl]quinazoline (K.1.51), 3-[(3,4-dichloroisothiazol-5-yl)methoxy]-1,2-benzothiazole 1,1-dioxide (K.1.52), N′-(2,5-dimethyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamidine (K.1.53);
- The fungicides described by common names, their preparation and their activity e.g. against harmful fungi is known (cf.: http://www.alanwood.net/pesticides/); these substances are commercially available.
- The fungicides described by IUPAC nomenclature, their preparation and their pesticidal activity is also known (cf. Can. J. Plant Sci. 48(6), 587-94, 1968; EPA 141 317; EP-A 152 031; EP-A 226 917; EPA 243 970; EPA 256 503; EP-A 428 941; EP-A 532 022; EP-A 1 028 125; EP-A 1 035 122; EPA 1 201 648; EPA 1 122 244, JP 2002316902; DE 19650197; DE 10021412; DE 102005009458; U.S. Pat. No. 3,296,272; U.S. Pat. No. 3,325,503; WO 98/46608; WO 99/14187; WO 99/24413; WO 99/27783; WO 00/29404; WO 00/46148; WO 00/65913; WO 01/54501; WO 01/56358; WO 02/22583; WO 02/40431; WO 03/10149; WO 03/11853; WO 03/14103; WO 03/16286; WO 03/53145; WO 03/61388; WO 03/66609; WO 03/74491; WO 04/49804; WO 04/83193; WO 05/120234; WO 05/123689; WO 05/123690; WO 05/63721; WO 05/87772; WO 05/87773; WO 06/15866; WO 06/87325; WO 06/87343; WO 07/82098; WO 07/90624, WO 11/028657, WO2012/168188, WO 2007/006670, WO 2011/77514; WO13/047749, WO 10/069882, WO 13/047441, WO 03/16303, WO 09/90181, WO13/007767, WO 13/010862, WO 13/127704, WO 13/024009, WO 13/024010 and WO 13/047441, WO 13/162072, WO 13/092224, WO 11/135833).
- In another embodiment of the invention, the carboxamide compound ii) of formula (Ia) and the fungicides of the above list with sections A) to K) can be used together for the methods of the present invention.
- In still another embodiment of the invention, the mixture comprising the carboxamide compounds i) and ii) and the fungicides of the above list with sections A) to K) can be used together for the methods of the present invention.
- With regard the use of the carboxamide compound I, preferably compound i) of formula (I), in mixtures together with one or more other active ingredients in the methods according to the present invention on cultivated plants, some combinations are especially preferred.
- With regard to the use in a pesticidal mixture of the present invention, a compound II selected from group of AChE-inhibitors as defined above is preferred, in particular selected from the group of carbamates, especially preferred carbofuran, benfuracarb or methomyl.
- Mixtures of the carboxamide compound i) of formula (I) as component I with carbofuran as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with carbofuran as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with carbofuran as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, a compound II selected from group of AChE-inhibitors as defined above is preferred, in particular selected from the group organophosphates, especially preferred chlorpyrifos and acephate.
- Mixtures of the carboxamide compound i) of formula (I) as component I with acephate as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with acephate as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with acephate as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with chlorpyrifos as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with chlorpyrifos as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with chlorpyrifos as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, a compound II selected from group of GABA-gated chloride channel antagonists as defined above is preferred, in particular group fiproles, especially preferred ethiprole and fipronil.
- Mixtures of the carboxamide compound i) of formula (I) as component I with fipronil as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with fipronil as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with fipronil as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, a compound II selected from group of Sodium channel modulators as defined above is preferred, in particular pyrethroids, especially preferred alpha-cypermethrin, bifenthrin, tefluthrin and cyhalothrin.
- Mixtures of the carboxamide compound i) of formula (I) as component I with alpha-cypermethrin as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with alpha-cypermethrin as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with alpha-cypermethrin as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with bifenthrin as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with bifenthrin as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with bifenthrin as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with tefluthrin as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with tefluthrin as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with tefluthrin as component II are another embodiment of this invention.
- Mixtures of the carboxamide preferably compound i) of formula (I) as component I with cyhalothrin as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with cyhalothrin as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with cyhalothrin as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, a compound II selected from group of Neonicotinoids as defined above is preferred, in particular clothianidin, dinotefuran, imidacloprid, thiacloprid, or thiamethoxam.
- Mixtures of the carboxamide compound i) of formula (I) as component I with thiamethoxam as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with thiamethoxam as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with thiamethoxam as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with clothianidin as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with clothianidin as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with clothianidin as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with dinotefuran as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with dinotefuran as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with dinotefuran as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with imidacloprid as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with imidacloprid as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with imidacloprid as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with thiacloprid as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with thiacloprid as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with thiacloprid as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the compound II is selected from group of Nicotinic acetylcholine receptor allosteric activators and is preferably spinosad or spinetoram.
- Mixtures of the carboxamide compound i) of formula (I) as component I with spinosad as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with spinosad as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with spinosad as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with spinetoram as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with spinetoram as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with spinetoram as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the compound II is selected from group of Chloride channel activators and is preferably an avermectin.
- Mixtures of the carboxamide compound i) of formula (I) as component I with emamectin as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with emamectin as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with emamectin as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with abamectin as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with abamectin as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with abamectin as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the compound II is selected from group of Selective homopteran feeding blockers and is preferably pymetrozine or flonicamid.
- Mixtures of the carboxamide compound i) of formula (I) as component I with pymetrozine as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with pymetrozine as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with pymetrozine as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with flonicamid as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with flonicamid as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with flonicamid as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the component II is selected from group of Mite growth inhibitors and is preferably etoxazole.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the component II is selected from the group of Uncouplers of oxidative phosphorylation via disruption of the proton gradient and is preferably chlorfenapyr.
- Mixtures of the carboxamide compound i) of formula (I) as component I with chlorfenapyr as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with chlorfenapyr as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with chlorfenapyr as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the component II is selected from group of Inhibitors of the chitin biosynthesis type 1) and is preferably buprofezin.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the component II is selected from group of Voltage-dependent sodium channel blockers) and is preferably metaflumizone or indoxacarb.
- Mixtures of the carboxamide compound i) of formula (I) as component I with metaflumizone as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with metaflumizone as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with metaflumizone as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the component II is selected from group of Inhibitors of the of acetyl CoA carboxylase and is preferably a Tetronic or Tetramic acid derivative, spirodiclofen, spiromesifen or spirotetramat.
- Mixtures of the carboxamide compound i) of formula (I) as component I with Tetronic Acid as component II are preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with Tetronic Acid as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with Tetronic Acid as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with Tetramic Acid as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with Tetramic Acid as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with Tetramic Acid as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with spirodiclofen as component II are also preferred
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with spirodiclofen as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with spirodiclofen as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with spiromesifen as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with spiromesifen as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with spiromesifen as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with spirotetramat as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with spirotetramat as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with spirotetramat as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the compound II is selected from group of Mitochondrial complex II electron transport inhibitors and is preferably cyflumetofen.
- With regard to the use in a pesticidal mixture of the present invention, in an embodiment of the invention, the compound II is selected from group of Ryanodine receptor-modulators and is preferably fubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole or cyantraniliprole.
- With regard to the use in a pesticidal mixture of the present invention, in another embodiment of the invention, the compound II selected from group of Ryanodine receptor-modulators may also be selected from a compound listed in and coded as
- M.28.5a) to M.28.5d), namely M.28.5a) N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5b) N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5c) N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5d) N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide;
- M.28.5h) to M.28.5l): M.28.5a) N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5b) N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5c) N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5d) N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5h) N-[4,6-dibromo-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide; M.28.5i) N-[2-(5-Amino-1,3,4-thiadiazol-2-yl)-4-chloro-6-methylphenyl]-3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide; M.28.5j) 3-Chloro-1-(3-chloro-2-pyridinyl)-N-[2,4-dichloro-6-[[(1-cyano-1-methylethyl)amino]carbonyl]phenyl]-1H-pyrazole-5-carboxamide; M.28.5k) 3-Bromo-N-[2,4-dichloro-6-(methylcarbamoyl)phenyl]-1-(3,5-dichloro-2-pyridyl)-1H-pyrazole-5-carboxamide; M.28.5l) N-[4-Chloro-2-[[(1,1-dimethylethyl)amino]carbonyl]-6-methylphenyl]-1-(3-chloro-2-pyridinyl)-3-(fluoromethoxy)-1H-pyrazole-5-carboxamide; or
- M.28.6: cyhalodiamide.
- Mixtures of the carboxamide compound i) of formula (I) as component I with flubendiamid as component 11 are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component 1 with flubendiamid as component 11 are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with flubendiamid as component 11 are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with chlorantraniliprole as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with chlorantraniliprole as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with chlorantraniliprole as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with cyantraniliprole as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with cyantraniliprole as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with cyantraniliprole as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with cyclaniliprole as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with cyclaniliprole as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with cyclaniliprole as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with tetraniliprole as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with tetraniliprole as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with tetraniliprole as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with triflumezopyrim as component II are especially preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with triflumezopyrim as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with triflumezopyrim as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with sulfoxaflor as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with sulfoxaflor as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with sulfoxaflor as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with afidopyropen as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with afidopyropen as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with afidopyropen as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with pyrifluquinazon as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with pyrifluquinazon as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with pyrifluquinazon as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with flupyradifuron as component II are also preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with flupyradifuron as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with flupyradifuron as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, a compound II selected from the group of the azoles is preferred, especially prochloraz, prothioconazole, tebuconazole and triticonazole, especially prothioconazole and triticonazole.
- Mixtures of the carboxamide compound i) of formula (I) as component I, with triticonazole as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with triticonazole as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with triticonazole as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I, with prothioconazole as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with prothioconazole as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with prothioconazole as component II are another embodiment of this invention.
- With regard to the use in a pesticidal mixture of the present invention, preferred is a compound II selected from the group of benomyl, carbendazim, epoxiconazole, fluquinconazole, flutriafol, flusilazole, metconazole, prochloraz, prothioconazole, tebuconazole, triticonazole, pyraclostrobin, trifloxystrobin, boscalid, dimethomorph, penthiopyrad, dodemorph, famoxadone, fenpropimorph, proquinazid, pyrimethanil, tridemorph, maneb, mancozeb, metiram, thiram, chlorothalonil, dithianon, flusulfamide, metrafenone, fluxapyroxad (N-(3′,4′,5′ trifluorobiphenyl-2 yl)-3-difluoromethyl-1-methyl-1H-pyrazole-4 carboxamide), bixafen, penflufen, sedaxane, isopyrazam, metalaxyl, thiophanate-methyl.
- Especially preferred is metalaxyl, thiophanate-methyl, pyraclostrobin and fluxapyroxad.
- Mixtures of the carboxamide compound i) of formula (I) as component I, with metalaxyl as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with metalaxyl as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with metalaxyl as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with thiophanate-methyl as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with thiophanate-methyl as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with thiophanate-methyl as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with pyraclostrobin as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with pyraclostrobin as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with pyraclostrobin as component II are another embodiment of this invention.
- Mixtures of the carboxamide compound i) of formula (I) as component I with fluxapyroxad as component II are particularly preferred.
- Mixtures of the carboxamide compound ii) of formula (Ia) as component I with fluxapyroxad as component II are another embodiment of this invention.
- Mixtures of carboxamide mixtures comprising the carboxamide compounds i) and ii) as component I with fluxapyroxad as component II are another embodiment of this invention.
- In a particular preferred embodiment, the mixture comprise as an additional component a compound against which the cultivated plant is resistant.
- Cultivated Plants
- Not only the use of the carboxamide compound I, preferably compound i) of formula (I), alone may display a synergistic effect between the trait of the cultivated plant and the applied compound, but also the use of mixtures of (1) the carboxamide compound I, preferably compound i) of formula (I), as component I, with (2) compounds II as defined herein as component II, in cultivated plants may display synergistic effects between the trait of the cultivated plant and the applied compounds.
- Thus, the present invention relates to methods for controlling pests of a cultivated plant, comprising the application of the carboxamide compound i) of formula (I), or a mixture of (1) the carboxamide compound i) of formula (I) as component I with (2) at least one compound II as component II as defined above to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth.
- The present invention further also relates to methods for controlling pests of a cultivated plant, comprising the application of the carboxamide compound ii) of formula (Ia), or a mixture of (1) the carboxamide compound ii) of formula (Ia) as component I with (2) at least one compound II as component II as defined above to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth.
- The present invention further also relates to methods for controlling pests of a cultivated plant, comprising the application of the mixture comprising the carboxamide compounds i) and ii), or a mixture of (1) the mixture comprising the carboxamide compounds i) and ii) as component I with (2) at least one compound II as component II as defined above to a cultivated plant, parts of such plant, plant propagation material, or at its locus of growth.
- It has also been found that the application of the carboxamide compound i) of formula (I) as defined above on cultivated plants provides enhanced plant health effects, compared to the plant health effects that are possible by application of the carboxamide compound i) of formula (I) on non-cultivated plants.
- It has further also been found that the application of the carboxamide compound ii) of formula (Ia) as defined above on cultivated plants provides enhanced plant health effects, compared to the plant health effects that are possible by application of the carboxamide compound ii) of formula (Ia) on non-cultivated plants.
- It has still further also been found that the application of the mixture comprising the carboxamide compounds i) and ii) as defined above on cultivated plants provides enhanced plant health effects, compared to the plant health effects that are possible by application of the mixture comprising the carboxamide compounds i) and ii) on non-cultivated plants.
- It has also been found that the application of a mixture of (1) the carboxamide compound i) of formula (I) as component I with (2) at least one compound II as defined above as component II on cultivated plants provides enhanced plant health effects, compared to the plant health effects that are possible by application of a mixture of (1) the carboxamide compound i) of formula (I) as component I with (2) at least one compound II as component II on non-cultivated plants.
- It has further also been found that the application of a mixture of (1) the carboxamide compound ii) of formula (Ia) as component I with (2) at least one compound II as defined above as component II on cultivated plants provides enhanced plant health effects, compared to the plant health effects that are possible by application of a mixture of (1) the carboxamide compound ii) of formula (Ia) as component I with (2) at least one compound II as component II on non-cultivated plants.
- It has further also been found that the application of a mixture of (1) the mixture comprising the carboxamide compounds i) and ii) as component I with (2) at least one compound II as defined above as component II on cultivated plants provides enhanced plant health effects, compared to the plant health effects that are possible by application of a mixture of (1) the mixture comprising the carboxamide compounds i) and ii) as component I with (2) at least one compound II as component II on non-cultivated plants.
- The term “health of a plant” or “plant health” is defined as a condition of the plant and/or its products which is determined by several aspects alone or in combination with each other such as yield, plant vigor, quality and tolerance to abiotic and/or biotic stress.
- It has to be emphasized that the above mentioned plant health effects are also present when the cultivated plant is not under biotic stress and in particular when the cultivated plant is not under pest pressure. It is evident that a cultivated plant suffering from fungal or insecticidal attack produces a smaller biomass and leads to a reduced yield as compared to a cultivated plant which has been subjected to curative or preventive treatment against the pathogenic fungus or any other relevant pest and which can grow without the damage caused by the biotic stress factor. However, the methods according to the invention lead to an enhanced plant health even in the absence of any biotic stress. This means that increased plant health cannot be explained just by the insecticidal (or herbicidal) activities of the carboxamide compound I, preferably compound i) of formula (I), or a mixture comprising the carboxamide compound I, preferably compound i) of formula (I) as component I with at least one compound II as component II, but are based on further activity profiles. Thus, the method of the present invention also be carried out in the absence of pest pressure.
- Each listed plant health indicator listed below, and which is selected from the groups consisting of yield, plant vigor, quality and tolerance to abiotic and/or biotic stress, is to be understood as a preferred embodiment of the present invention either each on its own or preferably in combination with each other.
- According to the present invention, “increased yield” of a cultivated plant means that the yield of a product of the respective cultivated plant is increased via application of the carboxamide compound I, preferably compound i) of formula (I), or a mixture of the carboxamide compound I, preferably compound i) of formula (I) as component I with at least one compound II as component II by a measurable amount over the yield of the same product of the respective control plant produced under the same conditions and also under application of the carboxamide compound I, preferably compound i) of formula (I) or a mixture comprising the carboxamide compound I, preferably compound i) of formula (I) as component I with at least one compound II as component II.
- Increased yield can be characterized, among others, by the following improved properties of the cultivated plant: increased plant weight, increased plant height, increased biomass such as higher overall fresh weight (FW), increased number of flowers per plant, higher grain and/or fruit yield, more tillers or side shoots (branches), larger leaves, increased shoot growth, increased protein content, increased oil content, increased starch content, increased pigment content, increased chlorophyll content (chlorophyll content has a positive correlation with the plant's photosynthesis rate and accordingly, the higher the chlorophyll content the higher the yield of a plant)
- “Grain” and “fruit” are to be understood as any cultivated plant product which is further utilized after harvesting, e.g. fruits in the proper sense, vegetables, nuts, grains, seeds, wood (e.g. in the case of silviculture plants), flowers (e.g. in the case of gardening plants, ornamentals) etc., that is anything of economic value that is produced by the plant.
- According to the present invention, the yield is increased by at least 4%, preferable by 5 to 10%, more preferable by 10 to 20%, or even 20 to 30%. In general, the yield increase may even be higher.
- Another indicator for the condition of the cultivated plant is the plant vigor. The plant vigor becomes manifest in several aspects such as the general visual appearance.
- Improved plant vigor can be characterized, among others, by the following improved properties of the cultivated plant: improved vitality of the cultivated plant, improved plant growth, improved plant development, improved visual appearance, improved plant stand (less plant verse/lodging), improved emergence, enhanced root growth and/or more developed root system, enhanced nodulation, in particular rhizobial nodulation, bigger leaf blade, bigger size, increased plant height, increased tiller number, increased number of side shoots, increased number of flowers per plant, increased shoot growth, enhanced photosynthetic activity (e.g. based on increased stomatal conductance and/or increased CO2 assimilation rate), enhanced pigment content-, earlier flowering, earlier fruiting, earlier and improved germination, earlier grain maturity, less non-productive tillers, less dead basal leaves, less input needed (such as fertilizers or water), greener leaves, complete maturation under shortened vegetation periods, less seeds needed, easier harvesting, faster and more uniform ripening, longer shelf-life, longer panicles, delay of senescence, stronger and/or more productive tillers, better extractability of ingredients, improved quality of seeds (for being seeded in the following seasons for seed production) and/or reduced production of ethylene and/or the inhibition of its reception by the cultivated plant.
- Another indicator for the condition of the cultivated plant is the “quality” of a cultivated plant and/or its products. According to the present invention, enhanced quality means that certain plant characteristics such as the content or composition of certain ingredients are increased or improved by a measurable or noticeable amount over the same factor of the control plant produced under the same conditions. Enhanced quality can be characterized, among others, by following improved properties of the cultivated plant or its product: increased nutrient content, increased protein content, increased content of fatty acids, increased metabolite content, increased carotenoid content, increased sugar content, increased amount of essential amino acids, improved nutrient composition, improved protein composition, improved composition of fatty acids, improved metabolite composition, improved carotenoid composition, improved sugar composition, improved amino acids composition, improved or optimal fruit color, improved leaf color, higher storage capacity, higher processability of the harvested products.
- Another indicator for the condition of the cultivated plant is the plants tolerance or resistance to biotic and/or abiotic stress factors. Biotic and abiotic stress, especially over longer terms, can have harmful effects on cultivated plants. Biotic stress is caused by living organisms while abiotic stress is caused for example by environmental extremes. According to the present invention, “enhanced tolerance or resistance to biotic and/or abiotic stress factors” means (1.) that certain negative factors caused by biotic and/or abiotic stress are diminished in a measurable or noticeable amount as compared to control plants exposed to the same conditions and (2.) that the negative effects are not diminished by a direct action of the carboxamide compound I, preferably compound i) of formula (I), or a mixture of (i) the carboxamide compound I, preferably compound i) of formula (I) as component I with (ii) at least one compound II as component II on the stress factors, e.g. by its insecticidal action, but rather by a stimulation of the cultivated plants' own defensive reactions against said stress factors.
- Negative factors caused by biotic stress such as pathogens and pests are widely known and range from dotted leaves to total destruction of the cultivated plant. Biotic stress can be caused by living organisms, such as competing plants (for example weeds), microorganisms (such as phythopathogenic fungi and/or bacteria) and/or viruses.
- Negative factors caused by abiotic stress are also well-known and can often be observed as reduced plant vigor (see above), for example: dotted leaves, “burned leaves”, reduced growth, less flowers, less biomass, less crop yields, reduced nutritional value of the crops, later crop maturity, to give just a few examples. Abiotic stress can be caused for example by: extremes in temperature such as heat or cold (heat stress/cold stress), strong variations in temperature, temperatures unusual for the specific season, drought (drought stress), extreme wetness, high salinity (salt stress), radiation (for example by increased UV radiation due to the decreasing ozone layer), increased ozone levels (ozone stress), organic pollution (for example by phytho-toxic amounts of pesticides), inorganic pollution (for example by heavy metal contaminants).
- As a result of biotic and/or abiotic stress factors, the quantity and the quality of the stressed cultivated plants, their crops and fruits decrease. As far as quality is concerned, reproductive development is usually severely affected with consequences on the crops which are important for fruits or seeds. Synthesis, accumulation and storage of proteins are mostly affected by temperature; growth is slowed by almost all types of stress; polysaccharide synthesis, both structural and storage is reduced or modified: these effects result in a decrease in biomass (yield) and in changes in the nutritional value of the product.
- Advantageous properties, obtained especially from treated seeds, are e.g. improved germination and field establishment, better vigor and/or a more homogen field establishment.
- As pointed out above, the above identified indicators for the health condition of a cultivated plant may be interdependent and may result from each other. For example, an increased resistance to biotic and/or abiotic stress may lead to a better plant vigor, e.g. to better and bigger crops, and thus to an increased yield. Inversely, a more developed root system may result in an increased resistance to biotic and/or abiotic stress. However, these interdependencies and interactions are neither all known nor fully understood and therefore the different indicators are described separately.
- In one embodiment the methods of the present invention effectuate an increased yield of a cultivated plant or its product.
- In another embodiment the methods of the present invention effectuate an increased vigor of a cultivated plant or its product.
- In another embodiment the methods of the present invention effectuate in an increased quality of a cultivated plant or its product.
- In yet another embodiment the methods of the present invention effectuate an increased tolerance and/or resistance of a cultivated plant or its product against biotic stress.
- In yet another embodiment the methods of the present invention effectuate an increased tolerance and/or resistance of a cultivated plant or its product against abiotic stress.
- In a preferred embodiment of the invention, the methods of the present invention increase the yield of cultivated plants.
- In a preferred embodiment of the invention, embodiment of the invention, the methods of the present invention increase the yield of cultivated plants such as the plant weight and/or the plant biomass (e.g. overall fresh weight) and/or the grain yield and/or the number of tillers.
- In another preferred embodiment of the invention, embodiment of the invention, the methods of the present invention increase the plant vigor of cultivated plants.
- In a more preferred embodiment of the invention, the methods of the present invention increase the yield of cultivated plants.
- In a most preferred embodiment of the invention, the methods of the present invention increase the yield of cultivated plants such as the plant weight and/or the plant biomass (e.g. overall fresh weight) and/or the grain yield and/or the number of tillers.
- Thus, the present invention also relates to methods increasing the plant health, in particular the yield of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound i) of formula (I), or a mixture of (1) the carboxamide compound i) of formula (I) as component I with (2) at least one compound II as component II to a cultivated plant, parts of such plant, its plant propagation material, or at its locus of growth.
- Thus, the present invention also relates to methods increasing the plant health, in particular the yield of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound ii) of formula (aI), or a mixture of (1) the carboxamide compound ii) of formula (Ia) as component I with (2) at least one compound II as component II to a cultivated plant, parts of such plant, its plant propagation material, or at its locus of growth.
- Thus, the present invention also relates to methods increasing the plant health, in particular the yield of a cultivated plant as compared to the respective non-modified control plant, comprising the application of a mixture comprising the carboxamide compounds i) and ii), or a mixture of (1) a mixture comprising the carboxamide compounds i) and ii) as component I with (2) at least one compound II as component II to a cultivated plant, parts of such plant, its plant propagation material, or at its locus of growth.
- The present invention also comprises plant propagation material, preferably seed, of a cultivated plant treated with the carboxamide compound i) of formula (I), or a mixture of the carboxamide compound i) of formula (I) as component I with at least one compound II as component
- The present invention further also comprises plant propagation material, preferably seed, of a cultivated plant treated with the carboxamide compound ii) of formula (Ia), or a mixture of the carboxamide compound ii) of formula (Ia) as component I with at least one compound II as component II.
- The present invention further also comprises plant propagation material, preferably seed, of a cultivated plant treated with a mixture comprising the carboxamide compounds i) and ii), or a mixture comprising the carboxamide compounds i) and ii) as component I together with at least one compound II as component II.
- The term cultivated plant(s) includes to “modified plant(s)” and “transgenic plant(s)”. In one embodiment of the invention, the term “cultivated plants” refers to “modified plants”. In one embodiment of the invention, the term “cultivated plants” refers to “transgenic plants”. “Modified plants” are those which have been modified by conventional breeding techniques. The term “modification” means in relation to modified plants a change in the genome, epigenome, transcriptome or proteome of the modified plant, as compared to the control, wild type, mother or parent plant whereby the modification confers a trait (or more than one trait) or confers the increase of a trait (or more than one trait) as listed below. Preferably, the term “cultivated plant” refers to a plant, which has been modified by mutagenesis or genetic engineering.
- The modification may result in the modified plant to be a different, for example a new plant variety than the parental plant.
- “Transgenic plants” are those, which genetic material has been modified by the use of recombinant DNA techniques that under natural circumstances can not readily be obtained by cross breeding, mutations or natural recombination, whereby the modification confers a trait (or more than one trait) or confers the increase of a trait (or more than one trait) as listed below as compared to the wild-type plant. Preferably, the term “transgenic plant” refers to a plant, which has been modified by genetic engineering.
- In one embodiment, one or more genes have been integrated into the genetic material of a genetically modified plant in order to improve certain properties of the plant, preferably increase a trait as listed below as compared to the wild-type plant. Such genetic modifications also include but are not limited to targeted post-translational modification of protein(s), or to post-transcriptional modifications of oligo- or polypeptides e.g. by glycosylation or polymer additions such as prenylated, acetylated, phosphorylated or farnesylated moieties or PEG moieties.
- In one embodiment under the term “modification” when referring to a transgenic plant or parts thereof is understood that the activity, expression level or amount of a gene product or the metabolite content is changed, e.g. increased or decreased, in a specific volume relative to a corresponding volume of a control, reference or wild-type plant or plant cell, including the de novo creation of the activity or expression.
- In one embodiment the activity of a polypeptide is increased or generated by expression or overexpresion of the gene coding for said polypeptide which confers a trait or confers the increase of a trait as listed below as compared to the control plant. The term “expression” or “gene expression” means the transcription of a specific gene or specific genes or specific genetic construct. The term “expression” or “gene expression” in particular means the transcription of a gene or genes or genetic construct into structural RNA (rRNA, tRNA), regulatory RNA (e.g. miRNA, RNAi, RNAa) or mRNA with or without subsequent translation of the latter into a protein. In another embodiment the term “expression” or “gene expression” in particular means the transcription of a gene or genes or genetic construct into structural RNA (rRNA, tRNA) or mRNA with or without subsequent translation of the latter into a protein. In yet another embodiment it means the transcription of a gene or genes or genetic construct into mRNA.
- The process includes transcription of DNA and processing of the resulting mRNA product. The term “increased expression” or “overexpression” as used herein means any form of expression that is additional to the original wild-type expression level.
- The term “expression of a polypeptide” is understood in one embodiment to mean the level of said protein or polypeptide, preferably in an active form, in a cell or organism.
- In one embodiment the activity of a polypeptide is decreased by decreased expression of the gene coding for said polypeptide which confers a trait or confers the increase of a trait as listed below as compared to the control plant. Reference herein to “decreased expression” or “reduction or substantial elimination” of expression is taken to mean a decrease in endogenous gene expression and/or polypeptide levels and/or polypeptide activity relative to control plants. It comprises further reducing, repressing, decreasing or deleting of an expression product of a nucleic acid molecule.
- The terms “reduction”, “repression”, “decrease” or “deletion” relate to a corresponding change of a property in an organism, a part of an organism such as a tissue, seed, root, tuber, fruit, leave, flower etc. or in a cell. Under “change of a property” it is understood that the activity, expression level or amount of a gene product or the metabolite content is changed in a specific volume or in a specific amount of protein relative to a corresponding volume or amount of protein of a control, reference or wild type. Preferably, the overall activity in the volume is reduced, decreased or deleted in cases if the reduction, decrease or deletion is related to the reduction, decrease or deletion of an activity of a gene product, independent whether the amount of gene product or the specific activity of the gene product or both is reduced, decreased or deleted or whether the amount, stability or translation efficacy of the nucleic acid sequence or gene encoding for the gene product is reduced, decreased or deleted.
- The terms “reduction”, “repression”, “decrease” or “deletion” include the change of said property in only parts of the subject of the present invention, for example, the modification can be found in compartment of a cell, like an organelle, or in a part of a plant, like tissue, seed, root, leave, tuber, fruit, flower etc. but is not detectable if the overall subject, i.e. complete cell or plant, is tested. Preferably, the “reduction”, “repression”, “decrease” or “deletion” is found cellular, thus the term “reduction, decrease or deletion of an activity” or “reduction, decrease or deletion of a metabolite content” relates to the cellular reduction, decrease or deletion compared to the wild type cell. In addition the terms “reduction”, “repression”, “decrease” or “deletion” include the change of said property only during different growth phases of the organism used in the inventive process, for example the reduction, repression, decrease or deletion takes place only during the seed growth or during blooming. Furthermore the terms include a transitional reduction, decrease or deletion for example because the used method, e.g. the antisense, RNAi, snRNA, dsRNA, siRNA, miRNA, ta-siRNA, cosuppression molecule, or ribozyme, is not stable integrated in the genome of the organism or the reduction, decrease, repression or deletion is under control of a regulatory or inducible element, e.g. a chemical or otherwise inducible promoter, and has therefore only a transient effect.
- Methods to achieve said reduction, decrease or deletion in an expression product are known in the art, for example from the international patent application WO 2008/034648, particularly in paragraphs [0020.1.1.1], [0040.1.1.1], [0040.2.1.1] and [0041.1.1.1].
- Reducing, repressing, decreasing or deleting of an expression product of a nucleic acid molecule in modified plants is known. Examples are canola i.e. double nill oilseed rape with reduced amounts of erucic acid and sinapins.
- Such a decrease can also be achieved for example by the use of recombinant DNA technology, such as antisense or regulatory RNA (e.g. miRNA, RNAi, RNAa) or siRNA approaches. In particular RNAi, snRNA, dsRNA, siRNA, miRNA, ta-siRNA, cosuppression molecule, ribozyme, or antisense nucleic acid molecule, a nucleic acid molecule conferring the expression of a dominant-negative mutant of a protein or a nucleic acid construct capable to recombine with and silence, inactivate, repress or reduces the activity of an endogenous gene may be used to decrease the activity of a polypeptide in a transgenic plant or parts thereof or a plant cell thereof used in one embodiment of the methods of the invention. Examples of transgenic plants with reduced, repressed, decreased or deleted expression product of a nucleic acid molecule are Carica papaya (Papaya plants) with the event name X17-2 of the University of Florida, Prunus domestica (Plum) with the event name C5 of the United States Department of Agriculture—Agricultural Research Service, or those listed in rows T9-48 and T9-49 of table 9 below. Also known are plants with increased resistance to nematodes for example by reducing, repressing, decreasing or deleting of an expression product of a nucleic acid molecule, e.g. from the PCT publication WO 2008/095886.
- The reduction or substantial elimination is in increasing order of preference at least 10%, 20%, 30%, 40% or 50%, 60%, 70%, 80%, 85%, 90%, or 95%, 96%, 97%, 98%, 99% or more reduced compared to that of control plants. Reference herein to an “endogenous” gene not only refers to the gene in question as found in a plant in its natural form (i.e., without there being any human intervention), but also refers to that same gene (or a substantially homologous nucleic acid/gene) in an isolated form subsequently (re)introduced into a plant (a transgene). For example, a transgenic plant containing such a transgene may encounter a substantial reduction of the transgene expression and/or substantial reduction of expression of the endogenous gene.
- The terms “control” or “reference” are exchangeable and can be a cell or a part of a plant such as an organelle like a chloroplast or a tissue, in particular a plant, which was not modified or treated according to the herein described process according to the invention. Accordingly, the plant used as control or reference corresponds to the plant as much as possible and is as identical to the subject matter of the invention as possible. Thus, the control or reference is treated identically or as identical as possible, saying that only conditions or properties might be different which do not influence the quality of the tested property other than the treatment of the present invention.
- It is possible that control or reference plants are wild-type plants. However, “control” or “reference” may refer to plants carrying at least one genetic modification, when the plants employed in the process of the present invention carry at least one genetic modification more than said control or reference plants. In one embodiment control or reference plants may be transgenic but differ from transgenic plants employed in the process of the present invention only by said modification contained in the transgenic plants employed in the process of the present invention.
- The term “wild type” or “wild-type plants” refers to a plant without said genetic modification. These terms can refer to a cell or a part of a plant such as an organelle like a chloroplast or a tissue, in particular a plant, which lacks said genetic modification but is otherwise as identical as possible to the plants with at least one genetic modification employed in the present invention. In a particular embodiment the “wild-type” plant is not transgenic.
- Preferably, the wild type is identically treated according to the herein described process according to the invention. The person skilled in the art will recognize if wild-type plants will not require certain treatments in advance to the process of the present invention, e.g. non-transgenic wild-type plants will not need selection for transgenic plants for example by treatment with a selecting agent such as a herbicide.
- The control plant may also be a nullizygote of the plant to be assessed. The term “nullizygotes” refers to a plant that has undergone the same production process as a transgenic, yet has lost the once acquired genetic modification (e.g. due to mendelian segregation) as the corresponding transgenic. If the starting material of said production process is transgenic, then nullizygotes are also transgenic but lack the additional genetic modification introduced by the production process. In the process of the present invention the purpose of wild-type and nullizygotes is the same as the one for control and reference or parts thereof. All of these serve as controls in any comparison to provide evidence of the advantageous effect of the present invention.
- Preferably, any comparison is carried out under analogous conditions. The term “analogous conditions” means that all conditions such as, for example, culture or growing conditions, soil, nutrient, water content of the soil, temperature, humidity or surrounding air or soil, assay conditions (such as buffer composition, temperature, substrates, pathogen strain, concentrations and the like) are kept identical between the experiments to be compared. The person skilled in the art will recognize if wild-type, control or reference plants will not require certain treatments in advance to the process of the present invention, e.g. non-transgenic wild-type plants will not need selection for transgenic plants for example by treatment with herbicide.
- In case that the conditions are not analogous the results can be normalized or standardized based on the control.
- The “reference”, “control”, or “wild type” is preferably a plant, which was not modified or treated according to the herein described process of the invention and is in any other property as similar to a plant, employed in the process of the present invention of the invention as possible. The reference, control or wild type is in its genome, transcriptome, proteome or metabolome as similar as possible to a plant, employed in the process of the present invention of the present invention. Preferably, the term “reference-” “control-” or “wild-type-” plant, relates to a plant, which is nearly genetically identical to the organelle, cell, tissue or organism, in particular plant, of the present invention or a part thereof preferably 90% or more, e.g. 95%, more preferred are 98%, even more preferred are 99.00%, in particular 99.10%, 99.30%, 99.50%, 99.70%, 99.90%, 99.99%, 99.999% or more. Most preferable the “reference”, “control”, or “wild type” is a plant, which is genetically identical to the plant, cell, a tissue or organelle used according to the process of the invention except that the responsible or activity conferring nucleic acid molecules or the gene product encoded by them have been amended, manipulated, exchanged or introduced in the organelle, cell, tissue, plant, employed in the process of the present invention.
- Preferably, the reference and the subject matter of the invention are compared after standardization and normalization, e.g. to the amount of total RNA, DNA, or protein or activity or expression of reference genes, like housekeeping genes, such as ubiquitin, actin or ribosomal proteins.
- The genetic modification carried in the organelle, cell, tissue, in particular plant used in the process of the present invention is in one embodiment stable e.g. due to a stable transgenic integration or to a stable mutation in the corresponding endogenous gene or to a modulation of the expression or of the behaviour of a gene, or transient, e.g. due to an transient transformation or temporary addition of a modulator such as an agonist or antagonist or inducible, e.g. after transformation with a inducible construct carrying a nucleic acid molecule under control of a inducible promoter and adding the inducer, e.g. tetracycline.
- In one embodiment preferred plants, from which “modified plants” and/or “transgenic plants” are be selected from the group consisting of cereals, such as maize (corn), wheat, barley sorghum, rice, rye, millet, triticale, oat, pseudocereals (such as buckwheat and quinoa), alfalfa, apples, banana, beet, broccoli, Brussels sprouts, cabbage, canola (rapeseed), carrot, cauliflower, cherries, chickpea, Chinese cabbage, Chinese mustard, collard, cotton, cranberries, creeping bentgrass, cucumber, eggplant, flax, grape, grapefruit, kale, kiwi, kohlrabi, melon, mizuna, mustard, papaya, peanut, pears, pepper, persimmons, pigeonpea, pineapple, plum, potato, raspberry, rutabaga, soybean, squash, strawberries, sugar beet, sugarcane, sunflower, sweet corn, tobacco, tomato, turnip, walnut, watermelon and winter squash,
- more preferably from the group consisting of alfalfa, canola (rapeseed), cotton, rice, maize, cerals (such as wheat, barley, rye, oat), soybean, fruits and vegetables (such as potato, tomato, melon, papaya), pome fruits (such as apple and pear), vine, sugarbeet, sugarcane, rape, citrus fruits (such as citron, lime, orange, pomelo, grapefruit, and mandarin) and stone fruits (such as cherry, apricot and peach), most preferably from cotton, rice, maize, cerals (such as wheat, barley, rye, oat), sorghum, squash, soybean, potato, vine, pome fruits (such as apple), citrus fruits (such as citron and orange), sugarbeet, sugarcane, rape, oilseed rape and tomatoes utmost preferably from cotton, rice, maize, wheat, barley, rye, oat, soybean, potato, vine, apple, pear, citron and orange.
- In another embodiment of the invention the cultivated plant is a gymnosperm plant, especially a spruce, pine or fir.
- In some preferred embodiments, the invention relates to methods and uses, wherein the carboxamide compound i) of formula (I) is applied in an application type which corresponds in each case to one row of Table AP-T.
- In some preferred embodiments, the invention relates to methods and uses, wherein the carboxamide compound i) of formula (I) as component I and at least one compound II as defined above as component II, are applied in an application type which corresponds in each case to one row of Table AP-T.
- In some other embodiments, the invention relates to methods and uses, wherein the carboxamide compound ii) of formula (Ia) is applied in an application type which corresponds in each case to one row of Table AP-T.
- In still some other embodiments, the invention relates to methods and uses, wherein a mixture comprising the carboxamide compounds i) and ii) is applied in an application type which corresponds in each case to one row of Table AP-T.
-
TABLE AP-T Appl. type Crop Pest AP-T-1 Soybeans Spodoptera littoralis AP-T-2 Soybeans Anticarsia gemmatalis AP-T-3 Soybeans Spodoptera exigua AP-T-4 Soybeans Stinkbug AP-T-5 Soybeans Helicoverpa sp. AP-T-6 Soybeans Spodoptera eridania AP-T-7 Corn Spodoptera Frugiperta AP-T-8 Corn Spodoptera exigua AP-T-9 Rice Sesamia inferens AP-T-10 Rice Cnaphalocerus medinalis AP-T-11 Rice Chilo suppressalis AP-T-12 Rice Leptocorisa oratorius AP-T-13 Rice Brown plant hopper AP-T-14 Cotton Spodoptera littoralis AP-T-15 Cotton Thrips spp. AP-T-16 Cotton Spodoptera eridania AP-T-17 Cotton Helicoverpa sp. - The cultivated plants are plants, which comprise at least one trait. The term “trait” refers to a property, which is present in the plant either by genetic engineering or by conventional breeding techniques. Each trait has to be assessed in relation to its respective control. Examples of traits are: herbicide tolerance, insect resistance by expression of bacterial toxins, fungal resistance or viral resistance or bacterial resistance, antibiotic resistance, stress tolerance, maturation alteration, content modification of chemicals present in the cultivated plant, preferably increasing the content of fine chemicals advantageous for applications in the field of the food and/or feed industry, the cosmetics industry and/or the pharmaceutical industry, modified nutrient uptake, preferably an increased nutrient use efficiency and/or resistance to conditions of nutrient deficiency, improved fiber quality, plant vigor, modified colour, fertility restoration, and male sterility.
- Principally, cultivated plants may also comprise combinations of the aforementioned traits, e.g. they may be tolerant to the action of herbicides and express bacertial toxins.
- Principally, all cultivated plants may also provide combinations of the aforementioned properties, e.g. they may be tolerant to the action of herbicides and express bacertial toxins.
- In the detailed description below, the term “plant” refers to a cultivated plant.
- Tolerance to herbicides can be obtained by creating insensitivity at the site of action of the herbicide by expression of a target enzyme which is resistant to herbicide; rapid metabolism (conjugation or degradation) of the herbicide by expression of enzymes which inactivate herbicide; or poor uptake and translocation of the herbicide. Examples are the expression of enzymes which are tolerant to the herbicide in comparison to wild type enzymes, such as the expression of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), which is tolerant to glyphosate (see e.g. Heck et. al, Crop Sci. 45, 2005, 329-339; Funke et. al, PNAS 103, 2006, 13010-13015; U.S. Pat. No. 5,188,642, U.S. Pat. No. 4,940,835, U.S. Pat. No. 5,633,435, U.S. Pat. No. 5,804,425, U.S. Pat. No. 5,627,061), the expression of glutamine synthase which is tolerant to glufosinate and bialaphos (see e.g. U.S. Pat. No. 5,646,024, U.S. Pat. No. 5,561,236) and DNA constructs coding for dicamba-degrading enzymes (see e.g. U.S. Pat. No. 7,105,724). Gene constructs can be obtained, for example, from micro-organism or plants, which are tolerant to said herbicides, such as the Agrobacterium strain CP4 EPSPS which is resistant to glyphosate; Streptomyces bacteria which are resistance to glufosinate; Arabidopsis, Daucus carota, Pseudomonoas spp. or Zea mais with chimeric gene sequences coding for HDDP (see e.g. WO 1996/38567, WO 2004/55191); Arabidopsis thaliana which is resistant to protox inhibitors (see e.g. US 2002/0073443).
- Tolerance to glyphosate can also be achieved by any one of the genes 2mepsps, epsps, gat4601, goxv247 or mepsps.
- Tolerance to glufosinate can be achieved by any one of the genes bar, pat or pat(syn).
- Preferably, the herbicide tolerant plant can be selected from cereals such as wheat, barley, rye, oat; canola, sorghum, soybean, rice, oil seed rape, sugar beet, sugarcane, grapes, lentils, sunflowers, alfalfa, pome fruits; stone fruits; peanuts; coffee; tea; strawberries; turf; vegetables, such as tomatoes, potatoes, cucurbits and lettuce, more preferably, the plant is selected from soybean, maize (corn), rice, cotton, oilseed rape in particular canola, tomatoes, potatoes, sugarcane, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat. More preferably, the cultivated plant is selected from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize), Glycine max L. (soybean), Triticum aestivum (wheat), and Oryza sativa L. (rice), preferably from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize) and Glycine max L. (soybean). Particularly preferably, the cultivated plant is Glycine max L. (soybean).
- Examples of commercial available transgenic plants with tolerance to herbicides, are the corn varieties “Roundup Ready Corn”, “Roundup Ready 2” (Monsanto), “Agrisure GT”, “Agrisure GT/CB/LL”, “Agrisure GT/RW”, “Agrisure 3000GT” (Syngenta), “YieldGard VT Rootworm/RR2” and “YieldGard VT Triple” (Monsanto) with tolerance to glyphosate; the corn varieties “Liberty Link” (Bayer), “Herculex I”, “Herculex RW”, “Herculex Xtra” (Dow, Pioneer), “Agrisure GT/CB/LL” and “Agrisure CB/LL/RW” (Syngenta) with tolerance to glufosinate; the soybean varieties “Roundup Ready Soybean” (Monsanto) and “Optimum GAT” (DuPont, Pioneer) with tolerance to glyphosate; the cotton varieties “Roundup Ready Cotton” and “Roundup Ready Flex” (Monsanto) with tolerance to glyphosate; the cotton variety “FiberMax Liberty Link” (Bayer) with tolerance to glufosinate; the cotton variety “BXN” (Calgene) with tolerance to bromoxynil; the canola varieties “Navigator” and “Compass” (Rhone-Poulenc) with bromoxynil tolerance; the canola variety “Roundup Ready Canola” (Monsanto) with glyphosate tolerance; the canola variety “InVigor” (Bayer) with glufosinate tolerance; the rice variety “Liberty Link Rice” (Bayer) with glulfosinate tolerance and the alfalfa variety “Roundup Ready Alfalfa” with glyphosate tolerance. Further transgenic plants with herbicide tolerance are commonly known, for instance alfalfa, apple, eucalyptus, flax, grape, lentils, oil seed rape, peas, potato, rice, sugar beet, sunflower, tobacco, tomatom turf grass and wheat with tolerance to glyphosate (see e.g. U.S. Pat. No. 5,188,642, U.S. Pat. No. 4,940,835, U.S. Pat. No. 5,633,435, U.S. Pat. No. 5,804,425, U.S. Pat. No. 5,627,061); beans, soybean, cotton, peas, potato, sunflower, tomato, tobacco, corn, sorghum and sugarcane with tolerance to dicamba (see e.g. U.S. Pat. No. 7,105,724 and U.S. Pat. No. 5,670,454); pepper, apple, tomato, millet, sunflower, tobacco, potato, corn, cucumber, wheat and sorghum with tolerance to 2,4-D (see e.g. U.S. Pat. No. 6,153,401, U.S. Pat. No. 6,100,446, WO 2005107437, U.S. Pat. No. 5,608,147 and U.S. Pat. No. 5,670,454); sugarbeet, potato, tomato and tobacco with tolerance to glufosinate (see e.g. U.S. Pat. No. 5,646,024, U.S. Pat. No. 5,561,236); canola, barley, cotton, lettuce, melon, millet, oats, potato, rice, rye, sorghum, soybean, sugarbeet, sunflower, tobacco, tomato and wheat with tolerance to acetolactate synthase (ALS) inhibiting herbicides, such as triazolopyrimidine sulfonamides, sulfonylureas and imidazolinones (see e.g. U.S. Pat. No. 5,013,659, WO 2006060634, U.S. Pat. No. 4,761,373, U.S. Pat. No. 5,304,732, U.S. Pat. No. 6,211,438, U.S. Pat. No. 6,211,439 and U.S. Pat. No. 6,222,100); cereals, sugar cane, rice, corn, tobacco, soybean, cotton, rapeseed, sugar beet and potato with tolerance to HPPD inhibitor herbicides (see e.g. WO 2004/055191, WO 199638567, WO 1997049816 and U.S. Pat. No. 6,791,014); wheat, soybean, cotton, sugar beet, rape, rice, sorghum and sugar cane with tolerance to protoporphyrinogen oxidase (PPO) inhibitor herbicides (see e.g. US 2002/0073443, US 20080052798, Pest Management Science, 61, 2005, 277-285). The methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
- Plants, which are capable of synthesising one or more selectively acting bacterial toxins, comprise for example at least one toxin from toxin-producing bacteria, especially those of the genus Bacillus, in particular plants capable of synthesising one or more insecticidal proteins from Bacillus cereus or Bacillus popliae; or insecticidal proteins from Bacillus thuringiensis, such as delta.-endotoxins, e.g. CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c, or vegetative insecticidal proteins (VIP), e.g. VIP1, VIP2, VIP3 or VIP3A; or insecticidal proteins of bacteria colonising nematodes, for example Photorhabdus spp. or Xenorhabdus spp., such as Photorhabdus luminescens, Xenorhabdus nematophilus; toxins produced by animals, such as scorpion toxins, arachnid toxins, wasp toxins and other insect-specific neurotoxins; toxins produced by fungi, such as Streptomycetes toxins, plant lectins, such as pea lectins, barley lectins or snowdrop lectins; agglutinins; proteinase inhibitors, such as trypsine inhibitors, serine protease inhibitors, patatin, cystatin, papain inhibitors; ribosome-inactivating proteins (RIP), such as ricin, maize-RIP, abrin, luffin, saporin or bryodin; steroid metabolism enzymes, such as 3-hydroxysteroidoxidase, ecdysteroid-UDP-glycosyl-transferase, cholesterol oxidases, ecdysone inhibitors, HMG-COA-reductase, ion channel blockers, such as blockers of sodium or calcium channels, juvenile hormone esterase, diuretic hormone receptors, stilbene synthase, bibenzyl synthase, chitinases and glucanases.
- In one embodiment a plant is capable of producing a toxin, lectin or inhibitor if it contains at least one cell comprising a nucleic acid sequence encoding said toxin, lectin, inhibitor or inhibitor producing enzyme, and said nucleic acid sequence is transcribed and translated and if appropriate the resulting protein processed and/or secreted in a constitutive manner or subject to developmental, inducible or tissue-specific regulation.
- In the context of the present invention there are to be understood delta.-endotoxins, for example CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c, or vegetative insecticidal proteins (VIP), for example VIP1, VIP2, VIP3 or VIP3A, expressly also hybrid toxins, truncated toxins and modified toxins. Hybrid toxins are produced recombinantly by a new combination of different domains of those proteins (see, for example, WO 02/15701). An example for a truncated toxin is a truncated Cry1A(b), which is expressed in the Bt11 maize from Syngenta Seed SAS, as described below. In the case of modified toxins, one or more amino acids of the naturally occurring toxin are replaced. In such amino acid replacements, preferably non-naturally present protease recognition sequences are inserted into the toxin, such as, for example, in the case of CryIIIA055, a cathepsin-D-recognition sequence is inserted into a CryIIIA toxin (see WO 2003/018810).
- Examples of such toxins or transgenic plants capable of synthesising such toxins are disclosed, for example, in EP-A-0 374 753, WO 93/07278, WO 95/34656, EP-A-0 427 529, EP-A451 878 and WO 2003/052073.
- Examples of genes conferring resistance to coleopteran insects include cry34Ab1, cry35 Ab1, cry3A, cry3Bb1, dvsnf7, and mcry3A.
- Examples of genes conferring resistance to lepidopteran insects include cry1A, cry1A.105, cry1Ab, cry1Ab-Ac, cry1Ac, cry1C, cry1F, cry1Fa2, cry2Ab2, cry2Ae, cry9c, mocry1F, pinII, vip3A(a), and vip3Aa20.
- The processes for the preparation of such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above. Cry1-type deoxyribonucleic acids and their preparation are known, for example, from WO 95/34656, EP-A0 367 474, EP-A-0 401 979 and WO 1990/13651.
- The toxin contained in the transgenic plants imparts to the plants tolerance to harmful insects. Such insects can occur in any taxonomic group of insects, but are especially commonly found in the beetles (Coleoptera), two-winged insects (Diptera) and butterflies (Lepidoptera).
- Preferably, the plant capable of expression of bacterial toxins is selected from cereals such as wheat, barley, rye, oat; canola, cotton, eggplant, lettuce, sorghum, soybean, rice, oil seed rape, sugar beet, sugarcane, grapes, lentils, sunflowers, alfalfa, pome fruits; stone fruits; peanuts;
- coffee; tea; strawberries; turf; vegetables, such as tomatoes, potatoes, cucurbits and lettuce, more preferably, the plant is selected from cotton, soybean, maize (corn), rice, tomatoes, potatoes, oilseed rape and cereals such as wheat, barley, rye and oat, most preferably from cotton, soybean, maize, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat. More preferably, the cultivated plant is selected from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize), Glycine max L. (soybean), Triticum aestivum (wheat), and Oryza sativa L. (rice), preferably from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize) and Glycine max L. (soybean). Particularly preferably, the cultivated plant is Glycine max L. (soybean).
- Examples of commercial available transgenic plants capable of expression of bacterial toxins are the corn varieties “YieldGard corn rootworm” (Monsanto), “YieldGard VT” (Monsanto), “Herculex RW” (Dow, Pioneer), “Herculex Rootworm” (Dow, Pioneer) and “Agrisure CRW” (Syngenta) with resistance against corn rootworm; the corn varieties “YieldGard corn borer” (Monsanto), “YieldGard VT Pro” (Monsanto), “Agrisure CB/LL” (Syngenta), “Agrisure 3000GT” (Syngenta), “Hercules I”, “Hercules II” (Dow, Pioneer), “KnockOut” (Novartis), “NatureGard” (Mycogen) and “StarLink” (Aventis) with resistance against corn borer, the corn varieties “Herculex I” (Dow, Pioneer) and “Herculex Xtra” (Dow, Pioneer) with resistance against western bean cutworm, corn borer, black cutworm and fall armyworm; the corn variety “YieldGard Plus” (Monsanto) with resistance against corn borer and corn rootworm; the cotton variety “Bollgard I“ ” (Monsanto) with resistance against tobacco budworm; the cotton varieties “Bollgard II” (Monsanto), WideStrike” (Dow) and “VipCot” (Syngenta) with resistance against tobacco budworm, cotton bollworm, fall armyworm, beet armyworm, cabbage looper, soybean lopper and pink bollworm; the potato varieties “NewLeaf”, “NewLeaf Y” and “NewLeaf Plus” (Monsanto) with tobacco hornworm resistance and the eggplant varieties “Bt brinjal”, “Dumaguete Long Purple”, “Mara” with resistance against brinjal fruit and shoot borer, bruit borer and cotton bollworm (see e.g. U.S. Pat. No. 5,128,130). Further transgenic plants with insect resistance are commonly known, such as yellow stemborer resistant rice (see e.g. Molecular Breeding, Volume 18, 2006, Number 1), lepidopteran resistant lettuce (see e.g. U.S. Pat. No. 5,349,124), resistant soybean (see e.g. U.S. Pat. No. 7,432,421) and rice with resistance against Lepidopterans, such as rice stemborer, rice skipper, rice cutworm, rice caseworm, rice leaffolder and rice armyworm (see e.g. WO 2001021821). The methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
- Preferably, plants, which are capable of synthesising antipathogenic substances are selected from soybean, maize (corn), rice, tomatoes, potato, banana, papaya, tobacco, grape, plum and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, tomatoes, potato, banana, papaya, oil seed rape, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- Plants, which are capable of synthesising antipathogenic substances having a selective action are for example plants expressing the so-called “pathogenesis-related proteins” (PRPs, see e.g. EP-A-0 392 225) or so-called “antifungal proteins” (AFPs, see e.g. U.S. Pat. No. 6,864,068). A wide range of antifungal proteins with activity against plant pathogenic fungi have been isolated from certain plant species and are common knowledge. Examples of such antipathogenic substances and transgenic plants capable of synthesising such antipathogenic substances are known, for example, from EP-A-0 392 225, WO 93/05153, WO 95/33818, and EP-A-0 353 191. Transgenic plants which are resistant against fungal, viral and bacterial pathogens are produced by introducing plant resistance genes. Numerous resistant genes have been identified, isolated and were used to improve plant resistant, such as the N gene which was introduced into tobacco lines that are susceptible to Tobacco Mosaic Virus (TMV) in order to produce TMV-resistant tobacco plants (see e.g. U.S. Pat. No. 5,571,706), the Prf gene, which was introduced into plants to obtain enhanced pathogen resistance (see e.g. WO 199802545) and the Rps2 gene from Arabidopsis thaliana, which was used to create resistance to bacterial pathogens including Pseudomonas syringae (see e.g. WO 199528423). Plants exhibiting systemic acquired resistance response were obtained by introducing a nucleic acid molecule encoding the TIR domain of the N gene (see e.g. U.S. Pat. No. 6,630,618). Further examples of known resistance genes are the Xa21 gene, which has been introduced into a number of rice cultivars (see e.g. U.S. Pat. No. 5,952,485, U.S. Pat. No. 5,977,434, WO 1999/09151, WO 1996/22375), the Rcg1 gene for colletotrichum resistance (see e.g. US 2006/225152), the prp1 gene (see e.g. U.S. Pat. No. 5,859,332, WO 2008/017706), the ppv-cp gene to introduce resistance against plum pox virus (see e.g. US PP15,154Ps), the P1 gene (see e.g. U.S. Pat. No. 5,968,828), genes such as Blb1, Blb2, Blb3 and RB2 to introduce resistance against Phytophthora infestans in potato (see e.g. U.S. Pat. No. 7,148,397), the LRPKml gene (see e.g. WO1999064600), the P1 gene for potato virus Y resistance (see e.g. U.S. Pat. No. 5,968,828), the HA5-1 gene (see e.g. U.S. Pat. No. 5,877,403 and U.S. Pat. No. 6,046,384), the PIP gene to introduce a broad resistant to viruses, such as potato virus X (PVX), potato virus Y (PVY), potato leafroll virus (PLRV) (see e.g. EP 0707069) and genes such as Arabidopsis N116, ScaM4 and ScaM5 genes to obtain fungal resistance (see e.g. U.S. Pat. No. 6,706,952 and EP 1018553). The methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
- Antipathogenic substances which can be expressed by such transgenic plants include, for example, ion channel blockers, such as blockers for sodium and calcium channels, for example the viral KP1, KP4 or KP6 toxins; stilbene synthases; bibenzyl synthases; chitinases; glucanases; the so-called “pathogenesis-related proteins”” (PRPs; see e.g. EP-A-0 392 225); antipathogenic substances produced by microorganisms, for example peptide antibiotics or heterocyclic antibiotics (see e.g. WO 1995/33818) or protein or polypeptide factors involved in plant pathogen defense (so-called “plant disease resistance genes”, as described in WO 2003/000906).
- Antipathogenic substances produced by the plants are able to protect the plants against a variety of pathogens, such as fungi, viruses and bacteria. Useful plants of elevated interest in connection with present invention are cereals, such as wheat, barley, rye and oat; soybean; maize; rice; alfalfa, cotton, sugar beet, sugarcane, tobacco, potato, banana, oil seed rape; pome fruits; stone fruits; peanuts; coffee; tea; strawberries; turf; vines and vegetables, such as tomatoes, potatoes, cucurbits, papaya, melon, lenses and lettuce, more preferably selected from soybean, maize (corn), alfalfa, cotton, potato, banana, papaya, rice, tomatoes and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, potato, tomato, oilseed rape, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- Transgenic plants with resistance against fungal pathogens, are, for examples, soybeans with resistance against Asian soybean rust (see e.g. WO 2008/017706); plants such as alfalfa, corn, cotton, sugar beet, oileed, rape, tomato, soybean, wheat, potato and tobacco with resistance against Phytophtora infestans (see e.g. U.S. Pat. No. 5,859,332, U.S. Pat. No. 7,148,397, EP 1334979); corn with resistance against leaf blights, ear rots and stalk rots (such as anthracnose leaf bligh, anthracnose stalk rot, diplodia ear rot, Fusarium verticilioides, Gibberella zeae and top dieback, see e.g. US 2006/225152); apples with resistance against apple scab (Venturia inaequalis, see e.g. WO 1999064600); plants such as rice, wheat, barley, rye, corn, oats, potato, melon, soybean and sorghum with resistance against fusarium diseases, such as Fusarium graminearum, Fusarium sporotrichioides, Fusarium lateritium, Fusarium pseudograminearum Fusarium sambucinum, Fusarium culmorum, Fusarium poae, Fusarium acuminatum, Fusarium equiseti (see e.g. U.S. Pat. No. 6,646,184, EP 1477557); plants, such as corn, soybean, cereals (in particular wheat, rye, barley, oats, rye, rice), tobacco, sorghum, sugarcane and potatoes with broad fungal resistance (see e.g. U.S. Pat. No. 5,689,046, U.S. Pat. No. 6,706,952, EP 1018553 and U.S. Pat. No. 6,020,129).
- Transgenic plants with resistance against bacterial pathogens and which are covered by the present invention, are, for examples, rice with resistance against Xylella fastidiosa (see e.g. U.S. Pat. No. 6,232,528); plants, such as rice, cotton, soybean, potato, sorghum, corn, wheat, balrey, sugarcane, tomato and pepper, with resistance against bacterial blight (see e.g. WO 2006/42145, U.S. Pat. No. 5,952,485, U.S. Pat. No. 5,977,434, WO 1999/09151, WO 1996/22375); tomato with resistance against Pseudomonas syringae (see e.g. Can. J. Plant Path., 1983, 5: 251-255).
- Transgenic plants with resistance against viral pathogens, are, for examples, stone fruits, such as plum, almond, apricot, cherry, peach, nectarine, with resistance against plum pox virus (PPV, see e.g. US PP15,154Ps, EP 0626449); potatoes with resistance against potato virus Y (see e.g. U.S. Pat. No. 5,968,828); plants such as potato, tomato, cucumber and leguminosaes which are resistant against tomato spotted wilt virus (TSWV, see e.g. EP 0626449, U.S. Pat. No. 5,973,135); corn with resistance against maize streak virus (see e.g. U.S. Pat. No. 6,040,496); papaya with resistance against papaya ring spot virus (PRSV, see e.g. U.S. Pat. No. 5,877,403, U.S. Pat. No. 6,046,384); cucurbitaceae, such as cucumber, melon, watermelon and pumpkin, and solanaceae, such as potato, tobacco, tomato, eggplant, paprika and pepper, with resistance against cucumber mosaic virus (CMV, see e.g. U.S. Pat. No. 6,849,780); cucurbitaceae, such as cucumber, melon, watermelon and pumkin, with resistance against watermelon mosaic virus and zucchini yellow mosaic virus (see e.g. U.S. Pat. No. 6,015,942); potatoes with resistance against potato leafroll virus (PLRV, see e.g. U.S. Pat. No. 5,576,202); potatoes with a broad resistance to viruses, such as potato virus X (PVX), potato virus Y (PVY), potato leafroll virus (PLRV) (see e.g. EP 0707069).
- Further examples of deregulated orcommercially available transgenic plants with modified genetic material capable of expression of antipathogenic substances are the following plants: Carica papaya (papaya), Event: 55-1/63-1; Cornell University, Carica papaya (Papaya); Event: (X17-2); University of Florida, Cucurbita pepo (Squash); Event: (CZW-3); Asgrow (USA); Seminis Vegetable Inc. (Canada), Cucurbita pepo (Squash); Event: (ZW20); Upjohn (USA); Seminis Vegetable Inc. (Canada), Prunus domestica (Plum); Event: (C5); United States Department of Agriculture—Agricultural Research Service, Solanum tuberosum L. (Potato); Event: (RBMT15-101, SEMT15-02, SEMT15-15); Monsanto Company and Solanum tuberosum L. (Potato); Event: (RBMT21-129, RBMT21-350, RBMT22-082); Monsanto Company.
- Transgenic plants with resistance against nematodes and which may be used in the methods of the present invention are, for examples, soybean plants with resistance to soybean cyst nematodes.
- Methods have been proposed for the genetic transformation of plants in order to confer increased resistance to plant parasitic nematodes. U.S. Pat. Nos. 5,589,622 and 5,824,876 are directed to the identification of plant genes expressed specifically in or adjacent to the feeding site of the plant after attachment by the nematode.
- Also known in the art are transgenic plants with reduced feeding structures for parasitic nematodes, e.g. plants resistant to herbicides except of those parts or those cells that are nematode feeding sites and treating such plant with a herbicide to prevent, reduce or limit nematode feeding by damaging or destroying feeding sites (e.g. U.S. Pat. No. 5,866,777).
- Use of RNAi to target essential nematode genes has been proposed, for example, in PCT Publication WO 2001/96584, WO 2001/17654, US 2004/0098761, US 2005/0091713, US 2005/0188438, US 2006/0037101, US 2006/0080749, US 2007/0199100, and US 2007/0250947.
- Transgenic nematode resistant plants have been disclosed, for example in the PCT publications WO 2008/095886 and WO 2008/095889.
- Plants which are resistant to antibiotics, such as kanamycin, neomycin and ampicillin. The naturally occurring bacterial nptII gene expresses the enzyme that blocks the effects of the antibiotics kanamycin and neomycin. The ampicillin resistance gene ampR (also known as blaTEM1) is derived from the bacterium Salmonella paratyphi and is used as a marker gene in the transformation of micro-organisms and plants. It is responsible for the synthesis of the enzyme beta-lactamase, which neutralises antibiotics in the penicillin group, including ampicillin. Transgenic plants with resistance against antibiotics, are, for examples potato, tomato, flax, canola, oilseed rape and corn (see e.g. Plant Cell Reports, 20, 2001, 610-615. Trends in Plant Science, 11, 2006, 317-319. Plant Molecular Biology, 37, 1998, 287-296. Mol Gen Genet., 257, 1998, 606-13.). Plant Cell Reports, 6, 1987, 333-336. Federal Register (USA), Vol. 60, No. 113, 1995, page 31139. Federal Register (USA), Vol. 67, No. 226, 2002, page 70392. Federal Register (USA), Vol. 63, No. 88, 1998, page 25194. Federal Register (USA), Vol. 60, No. 141, 1995, page 37870. Canadian Food Inspection Agency, FD/OFB-095-264-A, October 1999, FD/OFB-099-127-A, October 1999. Preferably, the plant is selected from soybean, maize (corn), rice, cotton, oilseed rape, potato, sugarcane, alfalfa, tomatoes and cereals, such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, oilseed rape, tomato, potato, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- Plants which are tolerant to stress conditions (see e.g. WO 2000/04173, WO 2007/131699, CA 2521729 and US 2008/0229448) are plants, which show increased tolerance to abiotic stress conditions such as drought, high salinity, high light intensities, high UV irradiation, chemical pollution (such as high heavy metal concentration), low or high temperatures, limited supply of nutrients (i.e. nitrogen, phosphorous) and population stress. Preferably, transgenic plants with resistance to stress conditions, are selected from rice, corn, soybean, sugarcane, alfalfa, wheat, tomato, potato, barley, rapeseed, beans, oats, sorghum and cotton with tolerance to drought (see e.g. WO 2005/048693, WO 2008/002480 and WO 2007/030001); corn, soybean, wheat, cotton, rice, rapeseed and alfalfa with tolerance to low temperatures (see e.g. U.S. Pat. No. 4,731,499 and WO 2007/112122); rice, cotton, potato, soybean, wheat, barley, rye, sorghum, alfalfa, grape, tomato, sunflower and tobacco with tolerance to high salinity (see e.g. U.S. Pat. No. 7,256,326, U.S. Pat. No. 7,034,139, WO 2001/030990). The methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above. Preferably, the plant is selected from soybean, maize (corn), rice, cotton, sugarcane, alfalfa, sugar beet, potato, oilseed rape, tomatoes and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, oilseed rape, tomato, potato, sugarcane, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- Altered maturation properties, are for example delayed ripening, delayed softening and early maturity. Preferably, transgenic plants with modified maturation properties, are, selected from tomato, melon, raspberry, strawberry, muskmelon, pepper and papaya with delayed ripening (see e.g. U.S. Pat. No. 5,767,376, U.S. Pat. No. 7,084,321, U.S. Pat. No. 6,107,548, U.S. Pat. No. 5,981,831, WO 1995035387, U.S. Pat. No. 5,952,546, U.S. Pat. No. 5,512,466, WO 1997001952, WO 1992/008798, Plant Cell. 1989, 53-63. Plant Molecular Biology, 50, 2002). The methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above. Preferably, the plant is selected from fruits, such as tomato, vine, melon, papaya, banana, pepper, raspberry and strawberry; stone fruits, such as cherry, apricot and peach; pome fruits, such as apple and pear; and citrus fruits, such as citron, lime, orange, pomelo, grapefruit, and mandarin; more preferably from tomato, vine, apple, banana, orange and strawberry, most preferably tomatoes.
- Content modification is synthesis of modified chemical compounds (if compared to the corresponding control plant) or synthesis of enhanced amounts of chemical (if compounds compared to the corresponding control plant) and corresponds to an increased or reduced amount of vitamins, amino acids, proteins and starch, different oils and a reduced amount of nicotine.
- Commercial examples are the soybean varieties “Vistive II” and “Visitive III” with low-linolenic/medium oleic content; the corn variety “Mavera high-value corn” with increased lysine content; and the soybean variety “Mavera high value soybean” with yielding 5% more protein compared to conventional varieties when processed into soybean meal. Further transgenic plants with altered content are, for example, potato and corn with modified amylopectin content (see e.g. U.S. Pat. No. 6,784,338, US 20070261136); canola, corn, cotton, grape, catalpa, cattail, rice, soybean, wheat, sunflower, balsam pear and vernonia with a modified oil content (see e.g. U.S. Pat. No. 7,294,759, U.S. Pat. No. 7,157,621, U.S. Pat. No. 5,850,026, U.S. Pat. No. 6,441,278, U.S. Pat. No. 6,380,462, U.S. Pat. No. 6,365,802, U.S. Pat. No. 6,974,898, WO 2001/079499, US 2006/0075515 and U.S. Pat. No. 7,294,759); sunflower with increased fatty acid content (see e.g. U.S. Pat. No. 6,084,164); soybeans with modified allergens content (so called “hypoallergenic soybean, see e.g. U.S. Pat. No. 6,864,362); tobacco with reduced nicotine content (see e.g. US 20060185684, WO 2005000352 and WO 2007064636); canola and soybean with increased lysine content (see e.g. Bio/Technology 13, 1995, 577-582); corn and soybean with altered composition of methionine, leucine, isoleucine and valine (see e.g. U.S. Pat. No. 6,946,589, U.S. Pat. No. 6,905,877); soybean with enhanced sulfur amino acid content (see e.g. EP 0929685, WO 1997041239); tomato with increased free amino acid contents, such as asparagine, aspartic acid, serine, threonine, alanine, histidine and glutamic acid (see e.g. U.S. Pat. No. 6,727,411); corn with enhanced amino acid content (see e.g. WO 05077117); potato, corn and rice with modified starch content (see e.g. WO 1997044471 and U.S. Pat. No. 7,317,146); tomato, corn, grape, alfalfa, apple, beans and peas with modified flavonoid content (see e.g. WO 2000/04175); corn, rice, sorghum, cotton, soybeans with altered content of phenolic compounds (see e.g. US 20080235829). The methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above. Preferably, the plant is selected from soybean, maize (corn), rice, cotton, sugarcane, potato, tomato, oilseed rape, flax and cereals such as wheat, barley, rye and oat, most preferably soybean, maize (corn), rice, oilseed rape, potato, tomato, cotton, vine, apple, pear, citron, orange and cereals such as wheat, barley, rye and oat.
- Enhanced nutrient utilization is e.g. assimilation or metabolism of nitrogen or phosphorous. Preferably, transgenic plants with enhanced nitrogen assimilatory and utilization capacities are selected from for example, canola, corn, wheat, sunflower, rice, tobacco, soybean, cotton, alfalfa, tomato, wheat, potato, sugar beet, sugar cane and rapeseed (see e.g. WO 1995/009911, WO 1997/030163, U.S. Pat. No. 6,084,153, U.S. Pat. No. 5,955,651 and U.S. Pat. No. 6,864,405). Plants with improved phosphorous uptake are, for example, tomato and potato (see e.g. U.S. Pat. No. 7,417,181). The methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above. Preferably, the plant is selected from soybean, maize (corn), rice, cotton, sugarcane, alfalfa, potato, oilseed rape and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), rice, cotton, oilseed rape, tomato, potato, vine, apple, pear, citron, orange and cereals such as wheat, barley.
- Transgenic plants with male sterility are preferably selected from canola, corn, tomato, rice, Indian mustard, wheat, soybean and sunflower (see e.g. U.S. Pat. No. 6,720,481, U.S. Pat. No. 6,281,348, U.S. Pat. No. 5,659,124, U.S. Pat. No. 6,399,856, U.S. Pat. No. 7,345,222, U.S. Pat. No. 7,230,168, U.S. Pat. No. 6,072,102, EP1 135982, WO 2001/092544 and WO 1996/040949). The methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above. Preferably, the plant is selected from soybean, maize (corn), rice, cotton, oilseed rape, tomato, potato, vine, apple, pear, citron, orange and cereals such as wheat, barley.
- Further examples of deregulated or commercially available transgenic plants with modified genetic material being male sterile are
- Brassica napus (Argentine Canola: (Event: MS1, RF1=>PGS1; Bayer CropScience (formerly Plant Genetic Systems); Brassica napus (Event: MS1, RF2=>PGS2; Bayer CropScience (formerly Plant Genetic Systems); Brassica napus (Event: MS8xRF3; Bayer CropScience (Aventis CropScience (AgrEvo)); Brassica napus (Event: PHY14, PHY35; Bayer CropScience (formerly Plant Genetic Systems); Brassica napus (Event: PHY36; Bayer CropScience (formerly Plant Genetic Systems); Cichorium intybus (Chicory: (Event: RM3-3, RM3-4, RM3-6; Bejo Zaden BV; Zea mays L. (Maize: (Event: 676, 678, 680; Pioneer Hi-Bred International Inc.; Zea mays L. (Event: MS3; Bayer CropScience (Aventis CropScience (AgrEvo)) and Zea mays L. (Event: MS6; Bayer CropScience (Aventis CropScience (AgrEvo)).
- Plants, which produce higher quality fiber are e.g. transgenic cotton plants. The such improved quality of the fiber is related to improved micronaire of the fiber, increased strength, improved staple length, improved length unifomity and color of the fibers (see e.g. WO 1996/26639, U.S. Pat. No. 7,329,802, U.S. Pat. No. 6,472,588 and WO 2001/17333). The methods of producing such transgenic plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
- As set forth above, cultivated plants may comprise one or more traits, e.g. selected from the group consisting of herbicide tolerance, insect resistance, fungal resistance, viral resistance, bacterial resistance, stress tolerance, maturation alteration, content modification, modified nutrient uptake and male sterility (see e.g. WO 2005033319 and U.S. Pat. No. 6,376,754).
- Examples of commercial available transgenic plants with two combined properties are the corn varieties “YieldGard Roundup Ready” and YieldGard Roundup Ready 2″ (Monsanto) with glyphosate tolerance and resistance to corn borer; the corn variety “Agrisure CB/LL” (Syntenta) with glufosinate tolerance and corn borer resistance; the corn variety “Yield Gard VT Rootworm/RR2” with glyphosate tolerance and corn rootworm resistance; the corn variety “Yield Gard VT Triple” with glyphosate tolerance and resistance against corn rootworm and corn borer; the corn variety “Herculex I” with glufosinate tolerance and lepidopteran resistance (Cry1F), i.e. against western bean cutworm, corn borer, black cutworm and fall armyworm; the corn variety “YieldGard Corn Rootworm/Roundup Ready 2” (Monsanto) with glyphosate tolerance and corn rootworm resistance; the corn variety “Agrisure GT/RW” (Syngenta) with gluphosinate tolerance and lepidopteran resistance (Cry3A), i.e. against western corn rootworm, northern corn rootworm and Mexican corn rootworm; the corn variety “Herculex RW” (Dow, Pioneer) with glufosinate tolerance and lepidopteran resistance (Cry34/35Ab1), i.e. against western corn rootworm, northern corn rootworm and Mexican corn rootworm; the corn variety “Yield Gard VT Rootworm/RR2” with glyphosate tolerance and corn rootworm resistance; the soybean variety “Optimum GAT” (DuPont, Pioneer) with glyphosate tolerance and ALS herbicide tolerance; the corn variety “Mavera high-value corn” with glyphosate tolerance, resistance to corn rootworm and European corn borer and high lysine trait.
- Examples of commercial available transgenic plants with three traits are the corn variety “Herculex I/Roundup Ready 2” with glyphosate tolerance, gluphosinate tolerance and lepidopteran resistance (Cry1F), i.e. against western bean cutworm, corn borer, black cutworm and fall armyworm; the corn variety “YieldGard Plus/Roundup Ready 2” (Monsanto) with glyphosate tolerance, corn rootworm resistance and corn borer resistance; the corn variety “Agrisure GT/CB/LL” (Syngenta) with tolerance to glyphosate tolerance, tolerance to gluphosinate and corn borer resistance; the corn variety “Herculex Xtra” (Dow, Pioneer) with glufosinate tolerance and lepidopteran resistance (Cry1F+Cry34/35Ab1), i.e. against western corn rootworm, northern corn rootworm, Mexican corn rootworm, western bean cutworm, corn borer, black cutworm and fall armyworm; the corn varieties “Agrisure CB/LL/RW” (Syngenta) with glufosinate tolerance, corn borer resistance (Cry1Ab) and lepidopteran resistance (Cry3A), i.e. against western corn rootworm, northern corn rootworm and Mexican corn rootworm; the corn variety “Agrisure 3000GT” (Syngenta) with glyphosate tolerance+corn borer resistance (Cry1Ab) and lepidopteran resistance (Cry3A), i.e. against western corn rootworm, northern corn rootworm and Mexican corn rootworm. The methods of producing such transgenic plants are generally known to the person skilled in the art.
- An example of a commercial available transgenic plant with four traits is “Hercules QuadStack” with glyphosate tolerance, glufosinate tolerance, corn borer resistance and corn rootworm resistance.
- In one embodiment of the invention, the commercial transgenic plant is a soybean variety with glyphosate tolerance and lepidopteran resistance, preferably with one trait of glyphosate tolerance and two traits of lepidopteran resistance. Preferably, the glyphosate tolerance is through expression of the EPSPS encoding gene from A. tumefaciens strain CP4, more preferably it is based on the transgenic event MON89788 (see A1-14, T1-100). Also preferably, the lepidopteran resistance is a resistance to lepidopteran pests of soybean, preferably through expression of the Cry1AC encoding gene from B. thuringiensis, preferably against velvetbean caterpillar (Anticarsia gemmatalis) and soybean looper (Pseudoplusia includens), more preferably it is based on the transgenic event MON87701.
- More preferably, the glyphosate tolerance is based on the transgenic event MON89788 and the trait of lepidopteran resistance is achieved through expression of the Cry1AC encoding gene from B. thuringiensis, preferably against velvetbean caterpillar (Anticarsia gemmatalis) and soybean looper (Pseudoplusia includens), more preferably based on the transgenic event MON87701.
- Most preferably, the commercial transgenic plant is “Intacta RR2 PRO” soybean (Monsanto) which claims to offer tolerance to glyphosate herbicide and protection against major soybean pests (velvetbean caterpilar, soybean looper, soybean budborer, bean shoot borer, bollworm, corn stalk borer, Helicoverpa, e.g. Helicoverpa armigera), along with increased yield potential.
- In another embodiment, the commercial transgenic plant is a soybean variety selected from “Roundup Ready 2 Yield”, “Intacta RR2 Pro” and “Vistive Gold” (all Monsanto), or “Stearidonic Acid (SDA) Omega-3” (higher content of SDA in soybean, Monsanto). In another embodiment, the trait is Bacillus thuringiensis Cry1A.105 and cry2Ab2 and Vector PV-GMIR13196, for Mon87751 soybean (Monsanto).
- In a further embodiment, the commercial transgenic plant is a corn variety which has aboveground insect protection from “Genuity VT Triple PRO” or “Herculex Xtra” or both of them, and herbicide tolerance from “Roundup Ready 2” and Liberty Link, preferably corn varieties selected from “Genuity SmartStax”, “Genuity VT Triple PRO” and “Genuity VT Double PRO” (all Monsanto), optionally as RIB (refuge-in-bag) solution. In a further embodiment, the commercial transgenic corn plant variety has a drought tolerance trait, preferably “Genuity DroughtGard”. In another embodiment, the trait is double-stranded ribonucleic acid (dsRNA), Bacillus thuringiensis Cry3Bb1 protein and vector PV-ZMIR10871 for MON87411 corn.
- In a further embodiment, the commercial transgenic plant is a cotton variety selected from “Bollgard II” (insect protection), “Roundup Ready Flex” (herbicide tolerance) and “Bollgard II with Roundup Ready Flex” (both), all Monsanto.
- Preferably, the cultivated plants are plants, which comprise at least one trait selected from herbicide tolerance, insect resistance by expression of bacertial toxins, fungal resistance or viral resistance or bacterial resistance by expression of antipathogenic substances, stress tolerance, content modification of chemicals present in the cultivated plant compared to the corresponding control plant.
- Most preferably, the cultivated plants are plants, which are tolerant to the action of herbicides and plants, which express bacterial toxins, which provides resistance against animal pests (such as insects or arachnids or nematodes), wherein the bacterial toxin is preferably a toxin from Bacillus thuriginensis. Herein, the plant is preferably selected from cotton, rice, maize, wheat, barley, rye, oat, soybean, potato, vine, apple, pear, citron and orange.
- In one embodiment, the plant is soybean.
- In one embodiment, the invention relates to a method for controlling pests and/or increasing the plant health of a cultivated plant with at least one modification as compared to the respective non-modified control plant, wherein the plant is soybean, which method comprises applying the carboxamide compound i) of formula (I), or a mixture of (1) the carboxamide compound i) of formula (I) as component I with (2) at least one compound II as component II.
- In another embodiment, the invention relates to a method for controlling pests and/or increasing the plant health of a cultivated plant with at least one modification as compared to the respective non-modified control plant, wherein the plant is soybean, which method comprises applying the carboxamide compound ii) of formula (Ia), or a mixture of (1) the carboxamide compound ii) of formula (Ia) as component I with (2) at least one compound II as component II.
- In another embodiment, the invention relates to a method for controlling pests and/or increasing the plant health of a cultivated plant with at least one modification as compared to the respective non-modified control plant, wherein the plant is soybean, which method comprises applying a mixture comprising the carboxamide compounds i) and ii), or a mixture of (1) a mixture comprising the carboxamide compounds i) and ii) as component I with (2) at least one compound II as component II.
- In an utmost preferred embodiment, the cultivated plants are plants, which are tolerant to the action of herbicides. Further guidance for specific combinations within this utmost preferred embodiment can be found in tables 1, 2, 14 and tables A, B and C.
- If such plants are used in the methods according to the present invention, the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise a herbicide III, to which the plant is tolerant.
- If such plants are used in the methods according to the present invention, the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise a herbicide III, to which the plant is tolerant.
- If such plants are used in the methods according to the present invention, the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) the mixture comprising the carboxide compounds i) and ii) with (2) at least one compound II may additionally comprise a herbicide III, to which the plant is tolerant.
- For example, if the cultivated plant is a cultivated plant tolerant to glyphosate, the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise glyphosate.
- For example, if the cultivated plant is a cultivated plant tolerant to glyphosate, the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise glyphosate.
- For example, if the cultivated plant is a cultivated plant tolerant to glyphosate, the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise glyphosate.
- For example, if the cultivated plant is a cultivated plant tolerant to glufonsinate, the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (i) the carboxamide compound i) of formula (I) with (ii) at least one compound II may additionally comprise glufonisate.
- For example, if the cultivated plant is a cultivated plant tolerant to glufonsinate, the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise glufonsinate.
- For example, if the cultivated plant is a cultivated plant tolerant to glufonsinate, the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise glufonsinate.
- For example, if the cultivated plant is a cultivated plant tolerant to a imidazolinone herbicide, the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (i) the carboxamide compound i) of formula (I) with (ii) at least one compound II may additionally comprise at least one imidazolinone herbicide. Herein, the imidazolinone herbicide is selected from imazamox, imazethapyr, imazapic, imazapyr, imazamethabenz or imazaquin.
- For example, if the cultivated plant is a cultivated plant tolerant to a imidazolinone herbicide, the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise at least one imidazolinone herbicide. Herein, the imidazolinone herbicide is selected from imazamox, imazethapyr, imazapic, imazapyr, imazamethabenz or imazaquin.
- For example, if the cultivated plant is a cultivated plant tolerant to a imidazolinone herbicide, the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise at least one imidazolinone herbicide. Herein, the imidazolinone herbicide is selected from imazamox, imazethapyr, imazapic, imazapyr, imazamethabenz or imazaquin.
- For example, if the cultivated plant is a cultivated plant tolerant to dicamba, the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise dicamba.
- For example, if the cultivated plant is a cultivated plant tolerant to dicamba, the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise dicamba.
- For example, if the cultivated plant is a cultivated plant tolerant to dicamba, the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise dicamba.
- For example, if the cultivated plant is a cultivated plant tolerant to sethoxidim, the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise sethoxidim.
- For example, if the cultivated plant is a cultivated plant tolerant to sethoxidim, the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise sethoxidim.
- For example, if the cultivated plant is a cultivated plant tolerant to sethoxidim, the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise sethoxidim.
- For example, if the cultivated plant is a cultivated plant tolerant to cycloxidim, the mixture comprising the carboxamide compound i) of formula (I), or the mixture of (1) the carboxamide compound i) of formula (I) with (2) at least one compound II may additionally comprise cyloxidim.
- For example, if the cultivated plant is a cultivated plant tolerant to cycloxidim, the mixture comprising the carboxamide compound ii) of formula (Ia), or the mixture of (1) the carboxamide compound ii) of formula (Ia) with (2) at least one compound II may additionally comprise cycloxidim.
- For example, if the cultivated plant is a cultivated plant tolerant to cycloxidim, the mixture comprising a mixture comprising the carboxamide compounds i) and ii), or the mixture of (1) a mixture comprising the carboxamide compounds i) and ii) with (2) at least one compound II may additionally comprise cycloxidim.
- Thus, the present invention also relates to ternary mixtures, comprising the carboxamide compound i) of formula (I), an insecticide II and a herbicide III. The present invention also relates to ternary mixtures, comprising the carboxamide compound ii) of formula (Ia), an insecticide II and a herbicide III. The present invention also relates to ternary mixtures, comprising the mixture comprising the carboxamide compounds i) and ii), an insecticide II and a herbicide III.
- In particular, the present invention also relates to ternary mixtures comprising two insecticides and a fungicide.
- In another particular embodiment, the present invention also relates to ternary mixtures comprising two fungicides and one insecticide.
- In another particular embodiment, the present invention also relates to ternary mixtures comprising an insectide, a fungicide and a herbicide.
- In dependence to the application methods of the present inventions, some mixture partners may be especially preferred.
- For example, in the mixtures for foliar application comprising at least one other active compound II as component II, that compound II is preferably selected from teflubenzuron, chlorefenapyr or from the class of diamides
- Thus for foliar application, mixtures, wherein the at least one compound II is teflubenzuron can be preferred.
- Alternatively or additionally, mixtures, wherein the at least one compound II is chlorfenapyr can be preferred.
- Alternatively or additionally, mixtures, wherein the at least one compound II is a ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide. Most preferably the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide.
- For example regarding other application methods, in the mixtures for seed treatment application comprising at least one other active compound II as component II, that compound II is preferably selected from thiamethoxam, fipronil or from the class of diamides
- Thus for foliar application, mixtures, wherein the at least one compound II is thiamethoxam can be preferred.
- Alternatively or additionally, mixtures, wherein the at least one compound II is fipronil can be preferred.
- Alternatively or additionally, mixtures, wherein the at least one compound II is a ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide. Most preferably the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide.
- Preferably, the cultivated plants are plants, which comprise at least one trait selected from herbicide tolerance, insect resistance for example by expression of one or more bacterial toxins, fungal resistance or viral resistance or bacterial resistance by expression of one or more antipathogenic substances, stress tolerance, nutrient uptake, nutrient use efficiency, content modification of chemicals present in the cultivated plant compared to the corresponding control plant.
- More preferably, the cultivated plants are plants, which comprise at least one trait selected from herbicide tolerance, insect resistance by expression of one or more bacterial toxins, fungal resistance or viral resistance or bacterial resistance by expression of one or more antipathogenic substances, stress tolerance, content modification of one or more chemicals present in the cultivated plant compared to the corresponding control plant.
- Most preferably, the cultivated plants are plants, which are tolerant to the action of herbicides and plants, which express one or more bacterial toxins, which provides resistance against one or more animal pests (such as insects or arachnids or nematodes), wherein the bacterial toxin is preferably a toxin from Bacillus thuriginensis. Herein, the cultivated plant is preferably selected from soybean, maize (corn), rice, cotton, sugarcane, alfalfa, potato, oilseed rape, tomatoes and cereals such as wheat, barley, rye and oat, most preferably from soybean, maize (corn), cotton, rice and cereals such as wheat, barley, rye and oat.
- Preference is given to cultivated plants, which are tolerant to the action of herbicides.
- Thus, in one preferred embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant is a plant, which is rendered tolerant to herbicides, more preferably to herbicides such as glutamine synthetase inhibitors, 5-enol-pyrovyl-shikimate-3-phosphate-synthase inhibitors, acetolactate synthase (ALS) inhibitors, protoporphyrinogen oxidase (PPO) inhibitors, auxine type herbicides, most preferably to herbicides such as glyphosate, glufosinate, imazapyr, imazapic, imazamox, imazethapyr, imazaquin, imazamethabenz methyl, dicamba and 2,4-D.
- In another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a plant, which is rendered tolerant to herbicides, more preferably to herbicides such as glutamine synthetase inhibitors, 5-enol-pyrovyl-shikimate-3-phosphate-synthase inhibitors, acetolactate synthase (ALS) inhibitors, protoporphyrinogen oxidase (PPO) inhibitors, auxine type herbicides, most preferably to herbicides such as glyphosate, glufosinate, imazapyr, imazapic, imazamox, imazethapyr, imazaquin, imazamethabenz methyl, dicamba and 2,4-D.
- In still another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant is a plant, which is rendered tolerant to herbicides, more preferably to herbicides such as glutamine synthetase inhibitors, 5-enol-pyrovyl-shikimate-3-phosphate-synthase inhibitors, acetolactate synthase (ALS) inhibitors, protoporphyrinogen oxidase (PPO) inhibitors, auxine type herbicides, most preferably to herbicides such as glyphosate, glufosinate, imazapyr, imazapic, imazamox, imazethapyr, imazaquin, imazamethabenz methyl, dicamba and 2,4-D.
- In a further one preferred embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant is a plant, which express at least one insecticidal toxin, preferably a toxin from Bacillus species, more preferably from Bacillus thuringiensis.
- In another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a plant, which express at least one insecticidal toxin, preferably a toxin from Bacillus species, more preferably from Bacillus thuringiensis.
- In still another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant is a plant, which express at least one insecticidal toxin, preferably a toxin from Bacillus species, more preferably from Bacillus thuringiensis.
- In the cases, where the cultivated plant has an arthropodicidal, preferably insecticidal, trait, it often occurs that the pest that should be combated becomes resistant to that trait.
- Resistance may be defined as ‘a heritable change in the sensitivity of a pest population that is reflected in the repeated failure of a product to achieve the expected level of control when used according to the label recommendation for that pest species’. (IRAC) Resistance therefore means that the original activity of a pesticide against the target organisms (arthropods, insects) decreases or is even lost, due to genetic or metabolic adaptation of the target organism.
- “Resistant” to an insecticide is understood to mean resistant to at least one insecticide or insecticidal trait, i.e. the insect may be resistant to only one, but also to several insecticides or insecticidal traits.
- In the present context of cultivated plants with at least one insecticidal trait, the resistance is against an insecticidal effect which is due to a genetic modification of a plant (modified or transgenic plant), which caused a resistance of the plant or crop to certain pests, especially insect pests, in susceptible insects.
- This is to be understood to include plants that are by the use of recombinant DNA techniques capable to synthesize one or more insecticidal proteins, especially those mentioned herein, especially those known from the bacterial genus Bacillus, particularly from Bacillus thuringiensis, such as endotoxins, e. g. CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c; vegetative insecticidal proteins (VIP), e. g. VIP1, VIP2, VIP3 or VIP3A; insecticidal proteins of bacteria colonizing nematodes, for example Photorhabdus spp. or Xenorhabdus spp., and so on.
- Therefore, in a most preferred embodiment, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant has at least one insecticidal trait, and wherein the harmful insects are resistant to that at least one insecticidal trait of the plant.
- In another embodiment, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant has at least one insecticidal trait, and wherein the harmful insects are resistant to that at least one insecticidal trait of the plant.
- In still another embodiment, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compound i) and ii), wherein the plant has at least one insecticidal trait, and wherein the harmful insects are resistant to that at least one insecticidal trait of the plant.
- Preferably, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant has at least one lepidopteran or coleopteran trait, and wherein the harmful insects are resistant to that lepidopteran or coleopteran insecticidal trait of the plant.
- The present invention also relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant has at least one lepidopteran or coleopteran trait, and wherein the harmful insects are resistant to that lepidopteran or coleopteran insecticidal trait of the plant.
- The present invention also relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant has at least one lepidopteran or coleopteran trait, and wherein the harmful insects are resistant to that lepidopteran or coleopteran insecticidal trait of the plant.
- Methods and uses of the invention as described herein may also involve a step of assessing whether insects are resistant to certain insecticides.
- This step will in general involve collecting a sample of insects from the area (e.g. crop, field, habitat) to be treated, before actually applying the carboxamide compound I, preferably compound i) of formula (I), and testing (for example using any suitable phenotypic, biochemical or molecular biological technique applicable) for resistance/sensitivity.
- In one embodiment, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant has at least one insecticidal trait, e.g. as listed in table A14 or B, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- In another embodiment, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant has at least one insecticidal trait, e.g. as listed in table A14 or B, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- In still another embodiment, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant has at least one insecticidal trait, e.g. as listed in table A14 or B, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- In a further preferred embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant is a plant, which shows increased resistance against fungal, viral and bacterial diseases, more preferably a plant, which expresses antipathogenic substances, such as antifungal proteins, or which has systemic acquired resistance properties.
- In another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a plant, which shows increased resistance against fungal, viral and bacterial diseases, more preferably a plant, which expresses antipathogenic substances, such as antifungal proteins, or which has systemic acquired resistance properties.
- In still another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with a mixture comprising carboxamide compounds i) and ii) as component I and at least one compound II as component II, wherein the plant is a plant, which shows increased resistance against fungal, viral and bacterial diseases, more preferably a plant, which expresses antipathogenic substances, such as antifungal proteins, or which has systemic acquired resistance properties.
- In another utmost preference, the cultivated plants are plants, which are given in table A.
- In a more preferred embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- In a more preferred embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating plant propagation materials, preferably seeds with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- In another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- In another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating plant propagation materials, preferably seeds with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- In another embodiment more preferred embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating cultivated plants, parts of such plants, plant propagation materials, or at their locus of growth with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- In another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of cultivated plants by treating plant propagation materials, preferably seeds with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant corresponds to a row of table A as defined above.
- For the purpose of the present invention, the cultivated plant is preferably selected from the group consisting of soybean, cotton and maize, wherein the plant has been made tolerant to the action of certain herbicides as described above. It is particularly preferred that the cultivated plant is selected from the group consisting of soybean, cotton and maize, wherein the plant has been made tolerant to the action of glyphosate herbicides.
- In one embodiment, the cultivated plant is a plant, which has been made tolerant to the action of glyphosate herbicides. In addition to the tolerance to glyphosate herbicides, the plant may have been made tolerant to other herbicides and/or resistant to certain insects, and/or the plant may have been genetically modified otherwise, e.g. in terms of abiotic stress tolerance, altered growth/yield, disease resistance, modified product quality or pollination control system.
- In a particularly preferred embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the mixture comprising the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- In a particularly preferred embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the mixture comprising the carboxamide compound i) of formula
- (I) as component I and at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- In particular, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant having the insecticidal trait corresponds to a row of table A14, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
-
TABLE A14 Developer/commercial No traits event crop plants A14-1 Glufosinate tolerance + DAS44406-6 Glycine max L. Dow AgroSciences Glyphosate tolerance + (soybean) LLC 2,4-D herbicide tolerance A14-2 Glufosinate tolerance + DAS68416-4 × Glycine max L. Dow AgroSciences Glyphosate tolerance + MON89788 (soybean) LLC 2,4-D herbicide tolerance A14-3 Glyphosate tolerance + FG72 (FGØ72- Glycine max L. Bayer CropScience Isoxaflutole tolerance 2, FGØ72-3) (soybean) and MS Technologies LLC A14-4 Glyphosate tolerance + MON 87712 Glycine max L. Monsanto Company Enhanced Photosynthesis/ (soybean) Yield A14-5 Glyphosate tolerance + MON87701 × Glycine max L. available, Monsanto Lepidopteran resistance MON89788 (soybean) Company; Intacta ™ Roundup Ready ™ 2 Pro A14-6 Glyphosate tolerance + MON87705 Glycine max L. available, Monsanto Modified oil/fatty acid (soybean) Company; Vistive Gold ™ A14-7 Glyphosate tolerance + MON87705 × Glycine max L. Monsanto Company Modified oil/fatty acid MON89788 (soybean) A14-8 Glyphosate tolerance + MON87708 Glycine max L. available, Monsanto Dicamba tolerance (soybean) Company, Genuity ® Roundup Ready ™ 2 Xtend ™ A14-9 Glyphosate tolerance + MON87708 × Glycine max L. Monsanto Company Dicamba tolerance MON89788 (soybean) A14-10 Glyphosate tolerance + MON87769 Glycine max L. Monsanto Company Modified oil/fatty acid (soybean) A14-11 Glyphosate tolerance + MON87769 × Glycine max L. Monsanto Company Modified oil/fatty acid MON89788 (soybean) A14-12 Glyphosate tolerance + COT102 × Gossypium hirsutum L. available, Monsanto Lepidopteran resistance + MON15985 × (cotton) Company; Antibiotic resistance + MON88913 Bollgard ® III × Visual marker Roundup Ready ™ Flex ™ A14-13 Glufosinate tolerance + 3006-210-23 × Gossypium hirsutum L. available, Dow Glyphosate tolerance + 281-24-236 × (cotton) AgroSciences LLC; Lepidopteran resistance + MON88913 × Widestrike ™ × Antibiotic resistance COT102 Roundup Ready Flex ™ × VIPCOT ™ Cotton A14-14 Glyphosate tolerance + COT102 × Gossypium hirsutum L. available, Syngenta Lepidopteran resistance + COT67B × (cotton) and Monsanto Company; Antibiotic resistance MON88913 VIPCOT ™ Roundup Ready Flex ™ Cotton A14-15 Glufosinate tolerance + GHB614 × Gossypium hirsutum L. available, Bayer Glyphosate tolerance LLCotton25 (cotton) CropScience; GlyTol ™ Liberty Link ™ A14-16 Glufosinate tolerance + GHB614 × Gossypium hirsutum L. Bayer CropScience Glyphosate tolerance + LLCotton25 × (cotton) Lepidopteran resistance + MON15985 Antibiotic resistance + Visual marker A14-17 Glyphosate tolerance + GHB614 × Gossypium hirsutum L. Bayer CropScience Lepidopteran resistance MON15985 (cotton) A14-18 Glufosinate tolerance + GHB614 × Gossypium hirsutum L. available, Bayer Glyphosate tolerance + T304-40 × (cotton) CropScience; Lepidopteran resistance GHB119 GlyTol ™ Liberty Link ™ A14-19 Glyphosate tolerance + MON1698 Gossypium hirsutum L. available, Monsanto Antibiotic resistance (cotton) Company; Roundup Ready ™ Cotton A14-20 Glufosinate tolerance + 3272 × Bt11 × Zea mays L. Syngenta Glyphosate tolerance + GA21 (corn, maize) Lepidopteran resistance + Modified alpha amylase + Mannose metabolism A14-21 Glufosinate tolerance + 3272 × BT11 × Zea mays L. Syngenta Glyphosate tolerance + MIR604 × (corn, maize) Coleopteran resistance + GA21 Lepidopteran resistance + Modified alpha amylase + Mannose metabolism A14-22 Glyphosate tolerance + 3272 × GA21 Zea mays L. Syngenta Modified alpha amylase + (corn, maize) Mannose metabolism A14-23 Glyphosate tolerance + 3272 × Zea mays L. Syngenta Coleopteran resistance + MIR604 × (corn, maize) Modified alpha amylase + GA21 Mannose metabolism A14-24 Glufosinate tolerance + 5307 × Zea mays L. available, Syngenta; Glyphosate tolerance + MIR604 × Bt11 × (corn, maize) Agrisure ® Duracade ™ Coleopteran resistance + TC1507 × 5122 Lepidopteran resistance + GA21 Modified alpha amylase + Mannose metabolism A14-25 Glufosinate tolerance + 5307 × Zea mays L. available, Syngenta; Glyphosate tolerance + MIR604 × Bt11 × (corn, maize) Agrisure ® Duracade ™ Coleopteran resistance + TC1507 × 5222 Lepidopteran resistance + GA21 × Modified alpha amylase + MIR162 Mannose metabolism A14-26 Glufosinate tolerance + 59122 × GA21 Zea mays L. Syngenta Glyphosate tolerance + (corn, maize) Coleopteran resistance A14-27 Glufosinate tolerance + 59122 × Zea mays L. Syngenta Glyphosate tolerance + MIR604 × (corn, maize) Coleopteran resistance + GA21 Mannose metabolism A14-28 Glufosinate tolerance + 59122 × Zea mays L. Syngenta Glyphosate tolerance + MIR604 × (corn, maize) Coleopteran resistance + TC1507 × Lepidopteran resistance + GA21 Mannose metabolism A14-29 Glufosinate tolerance + 59122 × Zea mays L. DuPont (Pioneer Hi- Glyphosate tolerance + MON810 × (corn, maize) Bred International Coleopteran resistance + NK603 Inc.) Lepidopteran resistance A14-30 Glufosinate tolerance + 59122 × Zea mays L. Monsanto Company Glyphosate tolerance + MON88017 (corn, maize) Coleopteran resistance A14-31 Glufosinate tolerance + 59122 × Zea mays L. Syngenta Glyphosate tolerance + TC1507 × (corn, maize) Coleopteran resistance + GA21 Lepidopteran resistance A14-32 Glufosinate tolerance + 98140 × 59122 Zea mays L. Dow AgroSciences Glyphosate tolerance + (corn, maize) LLC and DuPont Sulfonylurea tolerance + (Pioneer Hi-Bred Coleopteran resistance International Inc.) A14-33 Glufosinate tolerance + 98140 × Zea mays L. Dow AgroSciences Glyphosate tolerance + TC1507 (corn, maize) LLC and DuPont Sulfonylurea tolerance + (Pioneer Hi-Bred Lepidopteran resistance International Inc.) A14-34 Glufosinate tolerance + 98140 × Zea mays L. Dow AgroSciences Glyphosate tolerance + TC1507 × (corn, maize) LLC and DuPont Sulfonylurea tolerance + 59122 (Pioneer Hi-Bred Coleopteran resistance + International Inc.) Lepidopteran resistance A14-35 Glufosinate tolerance + Bt11 × 59122 × Zea mays L. Syngenta Glyphosate tolerance + GA21 (corn, maize) Coleopteran resistance + Lepidopteran resistance A14-36 Glufosinate tolerance + Bt11 × 59122 × Zea mays L. Syngenta Glyphosate tolerance + MIR604 × (corn, maize) Coleopteran resistance + GA21 Lepidopteran resistance + Mannose metabolism A14-37 Glufosinate tolerance + BT11 × 59122 × Zea mays L. available, Syngenta; Glyphosate tolerance + MIR604 × (corn, maize) Agrisure ® 3122 Coleopteran resistance + TC1507 × Lepidopteran resistance + GA21 Mannose metabolism A14-38 Glufosinate tolerance + Bt11 × 59122 × Zea mays L. Syngenta Glyphosate tolerance + TC1507 × (corn, maize) Coleopteran resistance + GA21 Lepidopteran resistance A14-39 Glufosinate tolerance + Bt11 × MIR162 × Zea mays L. available, Syngenta; Glyphosate tolerance + GA21 (corn, maize) Agrisure ® Viptera ™ Lepidopteran resistance + 3110 Mannose metabolism resistance A14-40 Glufosinate tolerance + Bt11 × MIR162 × Zea mays L. available, Syngenta; Glyphosate tolerance + MIR604 × (corn, maize) Agrisure ® Viptera ™ Coleopteran resistance + GA21 3111, Agrisure ® Lepidopteran resistance + Viptera ™ 4 Mannose metabolism A14-41 Glufosinate tolerance + Bt11 × MIR162 × Zea mays L. available, Syngenta; Glyphosate tolerance + TC1507 × (corn, maize) Agrisure ™ Viptera Lepidopteran resistance + GA21 3220 Mannose metabolism A14-42 Glufosinate tolerance + Bt11 × TC1507 × Zea mays L. Syngenta Glyphosate tolerance + GA21 (corn, maize) Lepidopteran resistance A14-43 Glyphosate tolerance + DAS40278 × Zea mays L. Dow AgroSciences 2,4-D herbicide tolerance NK603 (corn, maize) LLC A14-44 Glyphosate tolerance HCEM485 Zea mays L. Stine Seed Farm, (corn, maize) Inc (USA) A14-45 Glyphosate tolerance + MIR162 × Zea mays L. Syngenta Lepidopteran resistance + GA21 (corn, maize) Mannose metabolism A14-46 Glyphosate tolerance + MIR162 × Zea mays L. Syngenta Coleopteran resistance + MIR604 × (corn, maize) Lepidopteran resistance + GA21 Mannose metabolism A14-47 Glyphosate tolerance + MIR162 × Zea mays L. Syngenta Coleopteran resistance + TC1507 × (corn, maize) Lepidopteran resistance + GA21 Mannose metabolism A14-48 Glyphosate tolerance + MIR604 × Zea mays L. available, Syngenta; Coleopteran resistance + GA21 (corn, maize) Agrisure ™ GT/RW Mannose metabolism A14-49 Glyphosate tolerance + MIR604 × Zea mays L. DuPont (Pioneer Hi- Coleopteran resistance + NK603 (corn, maize) Bred International Mannose metabolism Inc.) A14-50 Glyphosate tolerance + MON801 Zea mays L. Monsanto Company Lepidopteran resistance + (MON80100) (corn, maize) antibiotic resistance A14-51 Glyphosate tolerance + MON810 Zea mays L. available, Monsanto Lepidopteran resistance + (corn, maize) Company; Yield- antibiotic resistance Card ™, Maize- Gard ™ A14-52 Glyphosate tolerance + MON87411 Zea mays L. Monsanto Company Coleopteran resistance (corn, maize) A14-53 Glyphosate tolerance MON87427 Zea mays L. available, Monsanto (corn, maize) Company; Roundup Ready ™ Maize A14-54 Glyphosate tolerance + MON87427 × Zea mays L. Monsanto Company Coleopteran resistance + MON89034 × (corn, maize) Lepidopteran resistance MON88017 A14-55 Glyphosate tolerance + + MON87427 × Zea mays L. Monsanto Company Lepidopteran resistance MON89034 × (corn, maize) NK603 A14-56 Glufosinate tolerance + MON87427 × Zea mays L. Monsanto Company Glyphosate tolerance + MON89Ø34 × (corn, maize) Coleopteran resistance + TC15Ø7 × Lepidopteran resistance MON88Ø17 × 59122 A14-57 Glyphosate tolerance + MON87460 × Zea mays L. Monsanto Company Coleopteran resistance + MON89034 × (corn, maize) Lepidopteran resistance + MON88017 Drought stress tolerance + Antibiotic resistance A14-58 Glyphosate tolerance + + MON87460 × Zea mays L. Monsanto Company Lepidopteran resistance + MON89034 × (corn, maize) Drought stress tolerance + NK603 Antibiotic resistance A14-59 Glyphosate tolerance + MON87460 × Zea mays L. Monsanto Company Drought stress tolerance + NK603 (corn, maize) Antibiotic resistance A14-60 Glufosinate tolerance + MON89034 × Zea mays L. Monsanto Company Glyphosate tolerance + 59122 × (corn, maize) Coleopteran resistance + MON88017 Lepidopteran resistance A14-61 Glufosinate tolerance + MON89034 × Zea mays L. Monsanto Company Glyphosate tolerance + TC1507 × (corn, maize) Coleopteran resistance + MON88017 Lepidopteran resistance A14-62 Glufosinate tolerance + MON89034 × Zea mays L. available, Monsanto Glyphosate tolerance + TC1507 × (corn, maize) Company; Genuity ® Coleopteran resistance + MON88017 × SmartStax ™ Lepidopteran resistance 59122 A14-63 Glufosinate tolerance + MON89034 × Zea mays L. Dow AgroSciences Glyphosate tolerance + TC1507 × (corn, maize) LLC Coleopteran resistance + MON88017 × Lepidopteran resistance + 59122 × 2,4-D herbicide tolerance DAS40278 A14-64 Glufosinate tolerance + MON89034 × Zea mays L. Dow AgroSciences Glyphosate tolerance + TC1507 × (corn, maize) LLC Coleopteran resistance + MON88017 × Lepidopteran resistance + DAS40278 2,4-D herbicide tolerance A14-65 Glufosinate tolerance + MON89034 × Zea mays L. available, Monsanto Glyphosate tolerance + TC1507 × (corn, maize) Company and Dow Lepidopteran resistance NK603 AgroSciences LLC; Power Core ™ A14-66 Glufosinate tolerance + MON89034 × Zea mays L. Dow AgroSciences Glyphosate tolerance + TC1507 × (corn, maize) LLC Lepidopteran resistance + NK603 × 2,4-D herbicide tolerance DAS40278 A14-67 Glufosinate tolerance + NK603 × Zea mays L. Syngenta and Monsanto Glyphosate tolerance + MON810 × (corn, maize) Company Coleopteran resistance + 4114 × MIR604 Lepidopteran resistance + Antibiotic resistance + Mannose metabolism A14-68 Glufosinate tolerance + NK603 × T25 Zea mays L. available, Monsanto Glyphosate tolerance + (corn, maize) Company; Roundup Antibiotic resistance Ready ™ Liberty Link ™ Maize A14-69 Glufosinate tolerance + TC1507 × Zea mays L. available, DuPont Glyphosate tolerance + 59122 × (corn, maize) (Pioneer Hi-Bred Coleopteran resistance + MON810 × International Inc.); Lepidopteran resistance + MIR604 × Optimum ™ Intrasect Mannose metabolism NK603 Xtrenne A14-70 Glufosinate tolerance + TC1507 × Zea mays L. DuPont (Pioneer Hi- Glyphosate tolerance + MON810 × (corn, maize) Bred International Coleopteran resistance + MIR604 × Inc.) Lepidopteran resistance + NK603 Antibiotic resistance + Mannose metabolism A14-71 Glufosinate tolerance + TC1507 × Zea mays L. available, DuPont Glyphosate tolerance + 59122 × (corn, maize) (Pioneer Hi-Bred Coleopteran resistance + MON810 × International Inc.); Lepidopteran resistance NK603 Optimum ™ Intrasect XTRA A14-72 Glufosinate tolerance + TC1507 × Zea mays L. Monsanto Company Glyphosate tolerance + 59122 × (corn, maize) and Dow AgroSciences Coleopteran resistance + MON88017 LLC Lepidopteran resistance A14-73 Glufosinate tolerance + TC1507 × Zea mays L. available, Dow Glyphosate tolerance + 59122 × (corn, maize) AgroSciences LLC Coleopteran resistance + NK603 and DuPont (Pioneer Lepidopteran resistance Hi-Bred International Inc.); Herculex XTRA ™ RR A14-74 Glufosinate tolerance + TC1507 × Zea mays L. DuPont (Pioneer Hi- Glyphosate tolerance + GA21 (corn, maize) Bred International Lepidopteran resistance Inc.) A14-75 Glufosinate tolerance + TC1507 × Zea mays L. available, DuPont Glyphosate tolerance + MIR604 × (corn, maize) (Pioneer Hi-Bred Coleopteran resistance + NK603 International Inc.); Lepidopteran resistance + Optimum ™ TRIsect Mannose metabolism A14-76 Glufosinate tolerance + TC1507 × Zea mays L. DuPont (Pioneer Hi- Glyphosate tolerance + MON810 × (corn, maize) Bred International Lepidopteran resistance + MIR162 × Inc.) Mannose metabolism NK603 A14-77 Glufosinate tolerance + TC1507 × Zea mays L. available, DuPont Glyphosate tolerance + MON810 × (corn, maize) (Pioneer Hi-Bred Lepidopteran resistance NK603 International Inc.); Optimum ™ Intrasect A14-78 Glufosinate tolerance + TC1507 × Zea mays L. Monsanto Company Glyphosate tolerance + MON88017 (corn, maize) and Dow AgroSciences Coleopteran resistance + LLC Lepidopteran resistance A14-79 Glyphosate tolerance VCO-Ø1981-5 Zea mays L. Genective S. A. (corn, maize) - In another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the mixture comprising the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- In a particularly preferred embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the mixture comprising the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- In particular, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant having the insecticidal trait corresponds to a row of table A14, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- In still another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the mixture comprising 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- In a particularly preferred embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the mixture comprising 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant is a glyphosate herbicide tolerant plant and corresponds to a row of table A14.
- In particular, the present invention relates to a method of controlling harmful insects by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant having the insecticidal trait corresponds to a row of table A14, and wherein the harmful insects are resistant to an insecticidal trait of the plant.
- Insect resistance, in particular lepidopteran resistance is of growing importance in GMO crops. Furthermore, it has been found that insects often become resistant to the crops, which have been modified in terms of insect resistance. It has been found that the carboxamide compound I, preferably compound i) of formula (I) are particularly suitable for combating insects, which have become resistant to the crops, which have been modified in terms of insect resistance. In particular, the carboxamide compound I, preferably compound i) of formula (I) may advantageously be applied in soybeans, which have been made resistant to insects.
- In one embodiment, the cultivated plant is soybean, which has been made resistant to lepidoperan insects. In addition to the resistance to lepidoperan insects, the soybean may have been made tolerant to certain herbicides and/or resistant to other insects, and/or the soybean may have been genetically modified otherwise, e.g. in terms of abiotic stress tolerance, altered growth/yield, disease resistance, modified product quality or pollination control system.
- In a particularly preferred embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- In a particularly preferred embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the carboxamide compound i) of formula (I), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- In another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- In another embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the carboxamide compound I, preferably compound ii) of formula (Ia), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- In another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- In another embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with a mixture comprising the carboxamide compounds i) and ii), wherein the plant is a lepidopteran insect resistant soybean and corresponds to a row of table B as provided above.
- Lepidopteran resistance of soybeans is typically achieved by introducing a gene selected from the group consisting of: cry1Ac (gene source: Bacillus thuringiensis subsp. Kurstaki strain H D73), cry1F (gene source: Bacillus thuringiensis var. aizawai), cry1A.105 (gene source: Bacillus thuringiensis subsp. Kumamotoensis), cry2Ab2 (gene source: Bacillus thuringiensis subsp. Kumamotoensis), and combinations thereof. In addition, the soybeans may be modified e.g. in terms of herbicide tolerance by introducing a suitable gene such as pat (gene source: Streptomyces viridochromogenes), which provides glufosinate tolerance or cp4 epsps (aroA:CP4) (gene source: Agrobacterium tumefaciens strain CP4), which provides glyphosate tolerance. Preferably, the soybeans are additionally modified in terms of glyphosate tolerance by introducing the gene cp4 epsps (aroA:CP4).
- In a particularly preferred embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound i) of formula (I), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- In a particularly preferred embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the carboxamide compound i) of formula (I), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- of formula
- In another embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with the carboxamide compound ii) of formula (Ia), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- In another embodiment, the present invention therefore relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with the carboxamide compound ii) of formula (Ia), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- In still another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or their locus of growth with a mixture comprising the carboxamide compounds i) and ii), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- In still another embodiment, the present invention relates to a method of controlling harmful insects and/or increasing the health of plants by treating plant propagation material, preferably seeds with a mixture comprising the carboxamide compounds i) and ii), wherein the plant is a lepidopteran insect resistant soybean, which has been modified by introducing at least one gene or at least one gene combination, which corresponds to a row of table C as provided above.
- The present invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound i) of formula (I), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is
-
- (i) Gossypium hirsutum L. (cotton) or Zea mays L. (maize) and comprises at least one gene selected from the group consisting of dvsnf7, cry1A, cry1Ab-Ac, cry1C, cry2Ab2, cry2Ae, mocry1F; or
- (ii) Glycine max L. (soybean), Triticum aestivum (wheat) or Oryza sativa L. (rice) and comprises at least one gene selected from the group consisting of cry34Ab1, cry35 Ab1, cry3A, cry3Bb1, dvsnf7, mcry3A, cry1A, cry1A.105, cry1Ab, cry1Ab-Ac, cry1Ac, cry1C, cry1F, cry1Fa2, cry2Ab2, cry2Ae, cry9c, mocry1F, pinII, vip3A(a), vip3Aa20.
- The invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound ii) of formula (Ia), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is
-
- (i) Gossypium hirsutum L. (cotton) or Zea mays L. (maize) and comprises at least one gene selected from the group consisting of dvsnf7, cry1A, cry1Ab-Ac, cry1C, cry2Ab2, cry2Ae, mocry1F; or
- (ii) Glycine max L. (soybean), Triticum aestivum (wheat) or Oryza sativa L. (rice) and comprises at least one gene selected from the group consisting of cry34Ab1, cry35 Ab1, cry3A, cry3Bb1, dvsnf7, mcry3A, cry1A, cry1A.105, cry1Ab, cry1Ab-Ac, cry1Ac, cry1C, cry1F, cry1Fa2, cry2Ab2, cry2Ae, cry9c, mocry1F, pinII, vip3A(a), vip3Aa20.
- The invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of a mixture comprising the carboxamide compounds i) and ii) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is
-
- (i) Gossypium hirsutum L. (cotton) or Zea mays L. (maize) and comprises at least one gene selected from the group consisting of dvsnf7, cry1A, cry1Ab-Ac, cry1C, cry2Ab2, cry2Ae, mocry1F; or
- (ii) Glycine max L. (soybean), Triticum aestivum (wheat) or Oryza sativa L. (rice) and comprises at least one gene selected from the group consisting of cry34Ab1, cry35 Ab1, cry3A, cry3Bb1, dvsnf7, mcry3A, cry1A, cry1A.105, cry1Ab, cry1Ab-Ac, cry1Ac, cry1C, cry1F, cry1Fa2, cry2Ab2, cry2Ae, cry9c, mocry1F, pinII, vip3A(a), vip3Aa20.
- Preferably, present invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound i) of formula (I), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is modified by at least one gene according to one row of table D.
-
TABLE D No. crop gene D-1 cotton dvsnf7 D-2 cotton cry1A D-3 cotton cry1Ab-Ac D-4 cotton cry1C D-5 cotton cry2Ab2 D-6 cotton cry2Ae D-7 cotton mocry1F D-8 maize dvsnf7 D-9 maize cry1A D-10 maize cry1Ab-Ac D-11 maize cry1C D-12 maize cry2Ab2 D-13 maize cry2Ae D-14 maize mocry1F D-15 soybean cry34Ab1 D-16 soybean cry35 Ab1 D-17 soybean cry3A D-18 soybean cry3Bb1 D-19 soybean dvsnf7 D-20 soybean mcry3A D-21 soybean cry1A D-22 soybean cry1A.105 D-23 soybean cry1Ab D-24 soybean cry1Ab-Ac D-25 soybean cry1Ac D-26 soybean cry1C D-27 soybean cry1F D-28 soybean cry1Fa2 D-29 soybean cry2Ab2 D-30 soybean cry2Ae D-31 soybean cry9c D-32 soybean mocry1F D-33 soybean pinII D-34 soybean vip3A(a) D-35 soybean vip3Aa20 D-36 wheat cry34Ab1 D-37 wheat cry35 Ab1 D-38 wheat cry3A D-39 wheat cry3Bb1 D-40 wheat dvsnf7 D-41 wheat mcry3A D-42 wheat cry1A D-43 wheat cry1A.105 D-44 wheat cry1Ab D-45 wheat cry1Ab-Ac D-46 wheat cry1Ac D-47 wheat cry1C D-48 wheat cry1F D-49 wheat cry1Fa2 D-50 wheat cry2Ab2 D-51 wheat cry2Ae D-52 wheat cry9c D-53 wheat mocry1F D-54 wheat pinII D-55 wheat vip3A(a) D-56 wheat vip3Aa20 D-57 rice cry34Ab1 D-58 rice cry35 Ab1 D-59 rice cry3A D-60 rice cry3Bb1 D-61 rice dvsnf7 D-62 rice mcry3A D-63 rice cry1A D-64 rice cry1A.105 D-65 rice cry1Ab D-66 rice cry1Ab-Ac D-67 rice cry1Ac D-68 rice cry1C D-69 rice cry1F D-70 rice cry1Fa2 D-71 rice cry2Ab2 D-72 rice cry2Ae D-73 rice cry9c D-74 rice mocry1F D-75 rice pinII D-76 rice vip3A(a) D-77 rice vip3Aa20 - In another embodiment, the invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound ii) of formula (Ia), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is modified by at least one gene according to one row of table D.
- In another embodiment, the invention also relates to a method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of a mixture comprising the carboxamide compounds i) and ii) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is modified by at least one gene according to one row of table D.
- Further preferred embodiments of the invention are those methods of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or at their locus of growth with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein the plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- Further embodiments of the invention are those methods of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or at their locus of growth with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein the plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- Further embodiments of the invention are those methods of controlling harmful insects and/or increasing the health of plants by treating cultivated plants, parts of such plants or at their locus of growth with the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein the plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In a more preferred embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is teflubenzuron and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is teflubenzuron and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is teflubenzuron and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In a more preferred embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is chlorfenapyr and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is chlorfenapyr and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is chlorfenapyr and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In a more preferred embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1. Most preferably the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide.
- In another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1. Most preferably the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide.
- In still another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by foliar application on cultivated plants or on foliar parts of such plants of the mixture of 1) a mixture comprising the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1. Most preferably the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide.
- In a more preferred embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is thiamethoxam and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is thiamethoxam and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In still another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of 1) a mixture of the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is thiamethoxam and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In a more preferred embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is fipronil and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is fipronil and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In still another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of 1) a mixture of the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is fipronil and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1.
- In a more preferred embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound i) of formula (I) as component I and at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1. Most preferably the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide.
- In another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture of the carboxamide compound ii) of formula (Ia) as component I and at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1. Most preferably the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide.
- In another embodiment, the present invention relates of methods of controlling harmful insects and/or increasing the health of plants by treating plant propagation material of cultivated plants, especially seeds, with the mixture 1) a mixture of the carboxamide compounds i) and ii) as component I and 2) at least one compound II as component II, wherein component II is ryanodine receptor-modulator selected from flubendiamid, chlorantraniliprole, cyclaniliprole, tetraniliprole, cyantraniliprole or from a group consisting of N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide and the cultivated plant expresses one or more genes selected from CP4 epsps, pat, bar, Cry1Ab, Cry1Ac, Cry3Bb1, Cry2Ab, Cry1F, Cry34Ab1 and Cry35Ab1. Most preferably the ryanodine receptor-modulator is N-[4,6-dichloro-2-[(diethyl-lambda-4-sulfanylidene)¬carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, N-[4-chloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxamide or N-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoro¬methyl)pyrazole-3-carboxamide.
- In view of the above, some following embodiments are particularly preferred in connection with the methods of the invention relating to cultivated pants.
- Preferred are e.g. methods for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound i) of formula (I), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth.
- Other embodiments of this invention are methods for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound ii) of formula (Ia), to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth.
- Other embodiments of this invention are e.g. methods for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of a mixture comprising the carboxamide compounds i) and ii) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth.
- Especially preferred are those methods, wherein the cultivated plant is a plant with at least one property selected from: herbicide tolerance, insect resistance, fungal resistance or viral resistance or bacterial resistance, stress tolerance, maturation alteration, content modification of chemicals present in the cultivated plant, modified nutrient uptake, antibiotic resistance and male sterility compared to the corresponding control plant respectively.
- Especially more preferred are those methods, wherein the yield of the cultivated plant is increased.
- In particular preferred are those methods, wherein the cultivated plant is
- a plant with at least one trait of the category herbicide tolerance,
a plant with at least one trait of the category insect resistance, or
a plant with at least two traits, wherein at least one trait is of the category of herbicide tolerance and at least one trait is of the category of insect resistance. - In case the cultivated plant has at least one trait of the category herbicide tolerance, the herbicide resistance is preferably selected from the group consisting of glyphosate tolerance, glufosinate tolerance, and imidazolinone tolerance, and is particularly preferably glyphosate tolerance.
- In case the cultivated plant has at least one trait of the category insect resistance, the insect resistance is preferably selected from the group consisting of lepidoperan resistance and coleopteran resistance, and is particularly preferably lepidopteran resistance.
- In case the cultivated plant has at least one trait of the category insect resistance, preferably at least two genes confer insect resistance to the cultivated plant.
- Furthermore those methods are preferably applied to cultivated plants, wherein the cultivated plant is selected from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize), Glycine max L. (soybean), Triticum aestivum (wheat), and Oryza sativa L. (rice), preferably from the group consisting of Gossypium hirsutum L. (cotton), Zea mays L. (maize) and Glycine max L. (soybean).
- Among these cultivated plants preferably are selected:
- Gossypium hirsutum L. (cotton) or Zea mays L. (maize) and comprises at least one gene selected from the group consisting of dvsnf7, cry1A, cry1Ab-Ac, cry1C, cry2Ab2, cry2Ae, mocry1F; or
Glycine max L. (soybean), Triticum aestivum (wheat) or Oryza sativa L. (rice) and comprises at least one gene selected from the group consisting of cry34Ab1, cry35 Ab1, cry3A, cry3Bb1, dvsnf7, mcry3A, cry1A, cry1A.105, cry1Ab, cry1Ab-Ac, cry1Ac, cry1C, cry1F, cry1Fa2, cry2Ab2, cry2Ae, cry9c, mocry1F, pinII, vip3A(a), vip3Aa20. - Regarding the modification of the preferred treated cultivated plants in the methods mentioned above, the modification is selected from the events provided in table A14.
- A method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound i) of formula (I) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is a soybean variety with glyphosate tolerance and lepidopteran resistance, wherein the glyphosate tolerance is preferably through the expression of the cp4epsps gene, and more preferably based on the transgenic event MON89788, and wherein the lepidopteran resistance is preferably through expression of the Cry1AC encoding gene from B. thuringiensis, preferably against velvetbean caterpillar (Anticarsia gemmatalis) and soybean looper (Pseudoplusia includens), and more preferably based on the transgenic event MON87701.
- Another method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of the carboxamide compound ii) of formula (Ia) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is a soybean variety with glyphosate tolerance and lepidopteran resistance, wherein the glyphosate tolerance is preferably through the expression of the cp4epsps gene, and more preferably based on the transgenic event MON89788, and wherein the lepidopteran resistance is preferably through expression of the Cry1AC encoding gene from B. thuringiensis, preferably against velvetbean caterpillar (Anticarsia gemmatalis) and soybean looper (Pseudoplusia includens), and more preferably based on the transgenic event MON87701.
- Still another method for controlling pests and/or increasing the plant health of a cultivated plant as compared to the respective non-modified control plant, comprising the application of a mixture comprising the carboxamide compounds i) and ii) to a plant with at least one modification, parts of such plant, plant propagation material, or at its locus of growth, wherein the cultivated plant is a soybean variety with glyphosate tolerance and lepidopteran resistance, wherein the glyphosate tolerance is preferably through the expression of the cp4epsps gene, and more preferably based on the transgenic event MON89788, and wherein the lepidopteran resistance is preferably through expression of the Cry1AC encoding gene from B. thuringiensis, preferably against velvetbean caterpillar (Anticarsia gemmatalis) and soybean looper (Pseudoplusia includens), and more preferably based on the transgenic event MON87701.
- Preferably the cultivated plant is “Intacta RR2 PRO” soybean (Monsanto), which claims to offer tolerance to glyphosate herbicide and protection against major soybean pests (velvetbean caterpilar, soybean looper, soybean budborer, bean shoot borer, bollworm, corn stalk borer, Helicoverpa, e.g. Helicoverpa armigera), along with increased yield potential.
- Regarding the application of the carboxamide compound i) of formula (I) in those methods, the carboxamide compound i) of formula (I) is applied to the plant propagation material of the cultivated plant. Preferably the plant propagation material are the seeds.
- Regarding the application of the carboxamide compound ii) of formula (Ia) in those methods, the carboxamide compound ii) of formula (Ia) is applied to the plant propagation material of the cultivated plant. Preferably the plant propagation material are the seeds.
- Regarding the application of a mixture comprising the carboxamide compounds i) and ii) in those methods, the mixture comprising the carboxamide compounds i) and ii) is applied to the plant propagation material of the cultivated plant. Preferably the plant propagation material are the seeds.
- In those methods described above, the carboxamide compound i) of formula (I) is applied in a mixture of (1) the carboxamide compound i) of formula (I), and (2) at least one further pesticidal compound II as component II, wherein the pesiticdal compound II is an insecticide or a fungicide.
- those methods described above, the carboxamide compound ii) of formula (Ia) is applied in a mixture of (1) the carboxamide compound ii) of formula (Ia), and (2) at least one further pesticidal compound II as component II, wherein the pesiticdal compound II is an insecticide or a fungicide.
those methods described above, the carboxamide compound i) of formula (I) is applied in a mixture of (1) a mixture comprising the carboxamide compounds i) and ii) and (2) at least one further pesticidal compound II as component II, wherein the pesiticdal compound II is an insecticide or a fungicide. - Formulations
- In the following, suitable formulations and applications in connection with the present application are disclosed. These preferred embodiments relate (1) to the mixture of the invention comprising the carboxamide compound i) of formula (I) as well as uses and methods comprising the application of said mixture and (2) to uses and methods comprising the application of the carboxamide compound i) of formula (I) according to the invention.
- When it is in the following referred to “the compound i) of formula (I)”, to “the compound of the present invention” or “the mixture of the invention”, it is to be understood that the embodiments are disclosed in combination with (1) the mixture of the invention as well as uses and methods comprising the application of said mixture and (2) uses and methods comprising the application of the carboxamide compound i) of formula (I) according to the invention, respectively.
- The mixture of the invention or the carboxamide compound i) of formula (I) may be provided in the form of an agrochemical composition comprising the carboxamide compound i) of formula (I) together with one or more other pesticidal active ingredient(s) and an auxiliary.
- An agrochemical composition comprises a pesticidally effective amount the carboxamide compound i) of formula (I), a pesticidally effective amount of the carboxamide compound ii) of formula (Ia) or a pesticidally effective amount of the mixture comprising the carboxamide compounds i) and ii).
- Other embodiments relate (1) to the mixture of the invention comprising the carboxamide compound ii) of formula (Ia) as well as uses and methods comprising the application of said mixture and (2) to uses and methods comprising the application of the carboxamide compound ii) of formula (Ia) according to the invention.
- When it is in the following referred to “the compound ii) of formula (Ia)”, to “the compound of the present invention” or “the mixture of the invention”, it is to be understood that the embodiments are disclosed in combination with (1) the mixture of the invention as well as uses and methods comprising the application of said mixture and (2) uses and methods comprising the application of the carboxamide compound ii) of formula (Ia) according to the invention, respectively.
- The mixture of the invention or the carboxamide compound ii) of formula (Ia) may be provided in the form of an agrochemical composition comprising the carboxamide compound ii) of formula (Ia) together with one or more other pesticidal active ingredient(s) and an auxiliary.
- Still other embodiments relate (1) to the mixture of the invention comprising the mixture comprising the carboxamide compounds i) and ii) as well as uses and methods comprising the application of said mixture and (2) to uses and methods comprising the application of the mixture comprising the carboxamide compounds i) and ii) according to the invention.
- When it is in the following referred to “mixture comprising the carboxamide compounds i) and ii)”, to “the compound of the present invention” or “the mixture of the invention”, it is to be understood that those embodiments are disclosed in combination with (1) the mixture of the invention as well as uses and methods comprising the application of said mixture and (2) uses and methods comprising the application of a mixture comprising the carboxamide compounds i) and ii) according to the invention, respectively.
- The mixture of the invention or the mixture comprising the carboxamide compounds i) and ii) may be provided in the form of an agrochemical composition comprising the mixture comprising the carboxamide compounds i) and ii) together with one or more other pesticidal active ingredient(s) and an auxiliary.
- An agrochemical composition comprises a pesticidally effective amount the carboxamide compound i) of formula (I), a pesticidally effective amount of the carboxamide compound ii) of formula (Ia) or a pesticidally effective amount of the mixture comprising the carboxamide compounds i) and ii).
- The term “pesticidally effective amount” is defined below.
- The formulations comprising the carboxamide compound i) of formula (I), compound ii) of formula (la) or a mixture comprising the carboxamide compounds i) and ii) of the present invention can be converted into customary types of agrochemical compositions, e. g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof. Examples for composition types are suspensions (e.g. SC, OD, FS), emulsifiable concentrates (e.g. EC), emulsions (e.g. EW, EO, ES, ME), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS, DP, DS), pressings (e.g. BR, TB, DT), granules (e.g. WG, SG, GR, FG, GG, MG), insecticidal articles (e.g. LN), as well as gel formulations for the treatment of plant propagation materials such as seeds (e.g. GF). These and further compositions types are defined in the “Catalogue of pesticide formulation types and international coding system”, Technical Mono-graph No. 2, 6th Ed. May 2008, CropLife International.
- The compositions are prepared in a known manner, such as described by Mollet and Grubemann, Formulation technology, Wiley VCH, Weinheim, 2001; or Knowles, New developments in crop protection product formulation, Agrow Reports DS243, T&F Informa, London, 2005.
- Examples for suitable auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfactants, dispersants, emulsifiers, wetters, adjuvants, solubilizers, penetration enhancers, protective colloids, adhesion agents, thickeners, humectants, repellents, attractants, feeding stimulants, compatibilizers, bactericides, anti-freezing agents, anti-foaming agents, colorants, tackifiers and binders.
- Suitable solvents and liquid carriers are water and organic solvents, such as mineral oil fractions of medium to high boiling point, e.g. kerosene, diesel oil; oils of vegetable or animal origin; aliphatic, cyclic and aromatic hydrocarbons, e. g. toluene, paraffin, tetrahydronaphthalene, alkylated naphthalenes; alcohols, e.g. ethanol, propanol, butanol, benzylalcohol, cyclo¬hexanol; glycols; DMSO; ketones, e.g. cyclohexanone; esters, e.g. lactates, carbonates, fatty acid esters, gamma-butyrolactone; fatty acids; phosphonates; amines; amides, e.g. N-methylpyrrolidone, fatty acid dimethylamides; and mixtures thereof.
- Suitable solid carriers or fillers are mineral earths, e.g. silicates, silica gels, talc, kaolins, limestone, lime, chalk, clays, dolomite, diatomaceous earth, bentonite, calcium sulfate, magnesium sulfate, magnesium oxide; polysaccharide powders, e.g. cellulose, starch; fertilizers, e.g. ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas; products of vegetable origin, e.g. cereal meal, tree bark meal, wood meal, nutshell meal, and mixtures thereof.
- Suitable surfactants are surface-active compounds, such as anionic, cationic, nonionic and amphoteric surfactants, block polymers, polyelectrolytes, and mixtures thereof. Such surfactants can be used as emulsifier, dispersant, solubilizer, wetter, penetration enhancer, protective colloid, or adjuvant. Examples of surfactants are listed in McCutcheon's, Vol. 1: Emulsifiers & Detergents, McCutcheon's Directories, Glen Rock, USA, 2008 (International Ed. or North American Ed.).
- Suitable anionic surfactants are alkali, alkaline earth or ammonium salts of sulfonates, sulfates, phosphates, carboxylates, and mixtures thereof. Examples of sulfonates are alkylarylsulfonates, diphenylsulfonates, alpha-olefin sulfonates, lignine sulfonates, sulfonates of fatty acids and oils, sulfonates of ethoxylated alkylphenols, sulfonates of alkoxylated arylphenols, sulfonates of condensed naphthalenes, sulfonates of dodecyl- and tridecylbenzenes, sulfonates of naphthalenes and alkyl¬naphthalenes, sulfosuccinates or sulfosuccinamates. Examples of sulfates are sulfates of fatty acids and oils, of ethoxylated alkylphenols, of alcohols, of ethoxylated alcohols, or of fatty acid esters. Examples of phosphates are phosphate esters. Examples of carboxylates are alkyl carboxylates, and carboxylated alcohol or alkylphenol ethoxylates.
- Suitable nonionic surfactants are alkoxylates, N-substituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants, and mixtures thereof. Examples of alkoxylates are compounds such as alcohols, alkylphenols, amines, amides, arylphenols, fatty acids or fatty acid esters which have been alkoxylated with 1 to 50 equivalents. Ethylene oxide and/or propylene oxide may be employed for the alkoxylation, preferably ethylene oxide. Examples of N-substituted fatty acid amides are fatty acid glucamides or fatty acid alkanolamides. Examples of esters are fatty acid esters, glycerol esters or monoglycerides. Examples of sugar-based surfactants are sorbitans, ethoxylated sorbitans, sucrose and glucose esters or alkylpolyglucosides. Examples of polymeric surfactants are homo- or copolymers of vinylpyrrolidone, vinylalcohols, or vinylacetate.
- Suitable cationic surfactants are quaternary surfactants, for example quaternary ammonium compounds with one or two hydrophobic groups, or salts of long-chain primary amines. Suitable amphoteric surfactants are alkylbetains and imidazolines. Suitable block polymers are block polymers of the A-B or A-B-A type comprising blocks of polyethylene oxide and polypropylene oxide, or of the A-B—C type comprising alkanol, polyethylene oxide and polypropylene oxide. Suitable polyelectrolytes are polyacids or polybases. Examples of polyacids are alkali salts of polyacrylic acid or polyacid comb polymers. Examples of polybases are polyvinylamines or polyethyleneamines.
- Suitable adjuvants are compounds, which have a neglectable or even no pesticidal activity themselves, and which improve the biological performance of the active ingredients(s) on the target. Examples are surfactants, mineral or vegetable oils, and other auxilaries. Further examples are listed by Knowles, Adjuvants and additives, Agrow Reports DS256, T&F Informa UK, 2006, chapter 5.
- Suitable thickeners are polysaccharides (e.g. xanthan gum, carboxymethylcellulose), anorganic clays (organically modified or unmodified), polycarboxylates, and silicates.
- Suitable bactericides are bronopol and isothiazolinone derivatives such as alkylisothiazolinones and benzisothiazolinones.
- Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.
- Suitable anti-foaming agents are silicones, long chain alcohols, and salts of fatty acids.
- Suitable colorants (e.g. in red, blue, or green) are pigments of low water solubility and water-soluble dyes. Examples are inorganic colorants (e.g. iron oxide, titan oxide, iron hexacyanoferrate) and organic colorants (e.g. alizarin-, azo- and phthalocyanine colorants).
- Suitable tackifiers or binders are polyvinylpyrrolidons, polyvinylacetates, polyvinyl alcohols, polyacrylates, biological or synthetic waxes, and cellulose ethers.
- Examples for composition types and their preparation are:
- i) Water-soluble concentrates (SL, LS)
- 10-60 wt % of the pesticidal active compound(s), and 5-15 wt % wetting agent (e.g. alcohol alkoxylates) are dissolved in water and/or in a water-soluble solvent (e.g. alcohols) up to 100 wt %. The active substance dissolves upon dilution with water.
- ii) Dispersible concentrates (DC)
- 5-25 wt % of the pesticidal active compound(s), and 1-10 wt % dispersant (e. g. polyvinylpyrrolidone) are dissolved in up to 100 wt % organic solvent (e.g. cyclohexanone). Dilution with water gives a dispersion.
- iii) Emulsifiable concentrates (EC)
- 15-70 wt % of the pesticidal active compound(s), and 5-10 wt % emulsifiers (e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate) are dissolved in up to 100 wt % water-insoluble organic solvent (e.g. aromatic hydrocarbon). Dilution with water gives an emulsion.
- iv) Emulsions (EW, EO, ES)
- 5-40 wt % of the pesticidal active compound(s), and 1-10 wt % emulsifiers (e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate) are dissolved in 20-40 wt % water-insoluble organic solvent (e.g. aromatic hydrocarbon). This mixture is introduced into up to 100 wt % water by means of an emulsifying machine and made into a homogeneous emulsion. Dilution with water gives an emulsion.
- v) Suspensions (SC, OD, FS)
- In an agitated ball mill, 20-60 wt % of the pesticidal active compound(s), are comminuted with addition of 2-10 wt % dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate), 0.1-2 wt % thickener (e.g. xanthan gum) and up to 100 wt % water to give a fine active substance suspension. Dilution with water gives a stable suspension of the active substance. For FS type composition up to 40 wt % binder (e.g. polyvinylalcohol) is added.
- vi) Water-dispersible granules and water-soluble granules (WG, SG)
- 50-80 wt % of the pesticidal active compound(s), are ground finely with addition of up to 100 wt % dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate) and prepared as water-dispersible or water-soluble granules by means of technical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substance.
- vii) Water-dispersible powders and water-soluble powders (WP, SP, WS)
- 50-80 wt % of the pesticidal active compound(s), are ground in a rotor-stator mill with ad-dition of 1-5 wt % dispersants (e.g. sodium lignosulfonate), 1-3 wt % wetting agents (e.g. alcohol ethoxylate) and up to 100 wt % solid carrier, e.g. silica gel. Dilution with water gives a stable dispersion or solution of the active substance.
- viii) Gel (GW, GF)
- In an agitated ball mill, 5-25 wt % of the pesticidal active compound(s), are comminuted with addition of 3-10 wt % dispersants (e.g. sodium lignosulfonate), 1-5 wt % thickener (e.g. carboxymethylcellulose) and up to 100 wt % water to give a fine suspension of the active substance. Dilution with water gives a stable suspension of the active substance.
- ix) Microemulsion (ME)
- 5-20 wt % of the pesticidal active compound(s), are added to 5-30 wt % organic solvent blend (e.g. fatty acid dimethylamide and cyclohexanone), 10-25 wt % surfactant blend (e.g. alkohol ethoxylate and arylphenol ethoxylate), and water up to 100%. This mixture is stirred for 1 h to produce spontaneously a thermodynamically stable microemulsion.
- x) Microcapsules (CS)
- An oil phase comprising 5-50 wt % of the pesticidal active compound(s), 0-40 wt % water insoluble organic solvent (e.g. aromatic hydrocarbon), 2-15 wt % acrylic monomers (e.g. methylmethacrylate, methacrylic acid and a di- or triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization initiated by a radi-cal initiator results in the formation of poly(meth)acrylate microcapsules. Alternatively, an oil phase comprising 5-50 wt % of the pesticidal active compound(s), 0-40 wt % water insoluble organic solvent (e.g. aromatic hydrocarbon), and an isocyanate monomer (e.g. diphenylme-thene-4,4′-diisocyanatae) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). The addition of a polyamine (e.g. hexamethylenediamine) results in the for-mation of a polyurea microcapsule. The monomers amount to 1-10 wt %. The wt % relate to the total CS composition.
- xi) Dustable powders (DP, DS)
- 1-10 wt % of pesticidal active compound(s), are ground finely and mixed intimately with up to 100 wt % solid carrier, e.g. finely divided kaolin.
- xii) Granules (GR, FG)
- 0.5-30 wt % of v, is ground finely and associated with up to 100 wt % solid carrier (e.g. silicate). Granulation is achieved by extrusion, spray-drying or the fluidized bed.
- xiii) Ultra-low volume liquids (UL)
- 1-50 wt % of pesticidal active compound(s), are dissolved in up to 100 wt % organic solvent, e.g. aromatic hydrocarbon.
- The compositions types i) to xi) may optionally comprise further auxiliaries, such as 0.1-1 wt % bactericides, 5-15 wt % anti-freezing agents, 0.1-1 wt % anti-foaming agents, and 0.1-1 wt % colorants.
- The agrochemical compositions generally comprise between 0.01 and 95%, preferably between 0.1 and 90%, and most preferably between 0.5 and 75%, by weight of active substance. The active substances are employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).
- Various types of oils, wetters, adjuvants, fertilizer, or micronutrients, and other pesticides (e.g. herbicides, insecticides, fungicides, growth regulators, safeners) may be added to the active substances or the compositions comprising them as premix or, if appropriate not until immediately prior to use (tank mix). These agents can be admixed with the compositions according to the invention in a weight ratio of 1:100 to 100:1, preferably 1:10 to 10:1.
- The user applies the composition according to the invention usually from a predosage de-vice, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system. Usually, the agrochemical composition is made up with water, buffer, and/or further auxiliaries to the desired application concentration and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained. Usually, 20 to 2000 liters, preferably 50 to 400 liters, of the ready-to-use spray liquor are applied per hectare of agricultural useful area.
- According to one embodiment, individual components of the composition according to the invention such as parts of a kit or parts of a binary or ternary mixture may be mixed by the user himself in a spray tank and further auxiliaries may be added, if appropriate.
- In a further embodiment, either individual components of the composition according to the invention or partially premixed components, e.g. components comprising pesticidal active compound(s), may be mixed by the user in a spray tank and further auxiliaries and additives may be added, if appropriate.
- In a further embodiment, either individual components of the composition according to the invention or partially premixed components, e. g. components comprising pesticidal active compound(s), can be applied jointly (e.g. after tank mix) or consecutively.
- Conventional seed treatment formulations include for example flowable concentrates FS, solutions LS, suspoemulsions (SE), powders for dry treatment DS, water dispersible powders for slurry treatment WS, water-soluble powders SS and emulsion ES and EC and gel formulation GF. These formulations can be applied to the seed diluted or undiluted. Application to the seeds is carried out before sowing, either directly on the seeds or after having pregerminated the latter. Preferably, the formulations are applied such that germination is not included.
- The active substance concentrations in ready-to-use formulations, which may be obtained after two-to-tenfold dilution, are preferably from 0.01 to 60% by weight, more preferably from 0.1 to 40% by weight.
- In a preferred embodiment a FS formulation is used for seed treatment. Typically, a FS formulation may comprise 1-800 g/l of active ingredient, 1-200 g/l Surfactant, 0 to 200 g/l antifreezing agent, 0 to 400 g/l of binder, 0 to 200 g/l of a pigment and up to 1 liter of a solvent, preferably water.
- Especially preferred FS formulations of the compound I, preferably compound i) of formula (I), for seed treatment usually comprise from 0.1 to 80% by weight (1 to 800 g/l) of the active ingredient, from 0.1 to 20% by weight (1 to 200 g/l) of at least one surfactant, e.g. 0.05 to 5% by weight of a wetter and from 0.5 to 15% by weight of a dispersing agent, up to 20% by weight, e.g. from 5 to 20% of an anti-freeze agent, from 0 to 15% by weight, e.g. 1 to 15% by weight of a pigment and/or a dye, from 0 to 40% by weight, e.g. 1 to 40% by weight of a binder (sticker/adhesion agent), optionally up to 5% by weight, e.g. from 0.1 to 5% by weight of a thickener, optionally from 0.1 to 2% of an anti-foam agent, and optionally a preservative such as a biocide, antioxidant or the like, e.g. in an amount from 0.01 to 1% by weight and a filler/vehicle up to 100% by weight.
- In the treatment of seed, the application rates of the carboxamide compound i) of formula (I), of the carboxamide compound ii) of formula (Ia) or of a mixture comprising the carboxamide compounds i) and ii), are generally from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, more preferably from 1 g to 1000 g per 100 kg of seed and in particular from 1 g to 200 g per 100 kg of seed, e.g. from 1 g to 100 g or from 5 g to 100 g per 100 kg of seed.
- The invention therefore also relates to seed comprising one of the carboxamide compound i) of formula (I), the carboxamide compound ii) of formula (Ia) or the mixture comprising the carboxamide compounds i) and ii). The amount of the carboxamide compound i) of formula (I), the carboxamide compound ii) of formula (Ia) or the mixture comprising the carboxamide compounds i) and ii) will in general vary from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed. For specific crops such as lettuce the rate can be higher.
- The present invention may be illustrated by the following example.
- The interaction between the carboxamide compound of the present invention (or compositions comprising it) and the cultivated plant may be evaluated in different test systems. As well for the comparison to non-cultivated plants or to mixtures (comprising the carboxamide compound) synergism may be shown.
- Synergism can be described as an interaction where the combined effect of two or more compounds is greater than the sum of the individual effects of each of the compounds. The presence of a synergistic effect in terms of percent control, between two mixing partners (X and Y) can be calculated using the Colby equation (Colby, S. R., 1967, Calculating Synergistic and Antagonistic Responses in Herbicide Combinations, Weeds, 15, 20-22):
- When the observed combined control effect is greater than the expected combined control effect (E), then the combined effect is synergistic.
- The following tests can demonstrate the control efficacy of compounds, mixtures or compositions of this invention on specific pests. However, the pest control protection afforded by the compounds, mixtures or compositions is not limited to the species described. In certain instances, combinations of a compound of this invention with other invertebrate pest control compounds or agents are found to exhibit synergistic effects against certain important invertebrate pests.
- The analysis of synergism or antagonism between the mixtures or compositions is determined using Colby's equation.
- B1: Test on cultivated soybeans
Trial is carried out under greenhouse conditions on soybean (genetically modified plant variety, e.g. roundup, growth stage 109). 12 treatments are compared in a complete randomized blocks (4 replications) with plot size of 1 m×3 meters. Only selected plants are considered for artificial infestation and evaluations.
Due to glyphosate timing for application on such cultivated soybeans, all treatments are applied in older plants (GS 109) otherwise a significant phytotoxicity is expected. Application is done, using 400 l/ha. All treatments are applied using a CO2 backpack (nozzle type TXVK-10). Temperature at the time of applications is around 25 to 30° C. and air humidity is between 30 and 100%. Soil condition is e.g. R4 (when <75% of surface is dried up) and the moisture is moist (normal).
Roundup Original® (Glyfosate-sal isopropilamina @360 g/L) is used in the rate of 867 g a.i./ha. Artificial infestation is done one day after the application. The species used is Anticarsia gemmatalis (Hübner) [Thermesia elegantula (Herrich-Schaffer, 1869)], Noctuidae. 5 plants/plot are infested with 3 larvae (stage L2) using an entomological metallic tweezers, totaling 15 larvae per repetition. Larvae used in this trial are e.g. provided by BASF in-house rearing laboratory, Campinas, Brazil.
A second infestation is held seven days after application in the same plants and using the same larval numbers. A third infestation might be done if necessary in order to observe residual activity.
The mortality (number) and eating damage (%) are evaluated with 01, 02, 05, 07, 14 and 21 DAA (days after application), comparing to untreated control plants.
Increased mortalities in combination with the application of roundup can be observed when compared to the untreated control plants:
Additionally, after 5 days after application at 12.5 g a.i./ha a reduction of feeding damage compared to the untreated controls can be observed. In another test, a non-cultivated (non-GM) soybean variety is treated with 12.5 g a.i./ha and showed less reduction in feeding damage compared to the untreated controls.
Claims (26)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15/563,120 US11064696B2 (en) | 2015-04-07 | 2016-04-06 | Use of an insecticidal carboxamide compound against pests on cultivated plants |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562143847P | 2015-04-07 | 2015-04-07 | |
EP15201358 | 2015-12-18 | ||
EP15201358 | 2015-12-18 | ||
EP15201358.7 | 2015-12-18 | ||
PCT/EP2016/057502 WO2016162371A1 (en) | 2015-04-07 | 2016-04-06 | Use of an insecticidal carboxamide compound against pests on cultivated plants |
US15/563,120 US11064696B2 (en) | 2015-04-07 | 2016-04-06 | Use of an insecticidal carboxamide compound against pests on cultivated plants |
Publications (3)
Publication Number | Publication Date |
---|---|
US20180199570A1 US20180199570A1 (en) | 2018-07-19 |
US20190021322A9 true US20190021322A9 (en) | 2019-01-24 |
US11064696B2 US11064696B2 (en) | 2021-07-20 |
Family
ID=54979486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US15/563,120 Active 2036-07-16 US11064696B2 (en) | 2015-04-07 | 2016-04-06 | Use of an insecticidal carboxamide compound against pests on cultivated plants |
Country Status (3)
Country | Link |
---|---|
US (1) | US11064696B2 (en) |
CA (1) | CA2980505A1 (en) |
WO (1) | WO2016162371A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102310373B1 (en) * | 2013-10-18 | 2021-10-08 | 바스프아그로케미칼 프로덕츠 비.브이. | Agricultural mixtures comprising carboxamide compound |
US11219211B2 (en) | 2015-03-11 | 2022-01-11 | Basf Agrochemical Products B.V. | Pesticidal mixture comprising a carboxamide compound and a biopesticide |
US11297837B2 (en) | 2016-02-19 | 2022-04-12 | Basf Se | Pesticidally activi mixtures comprising anthranilamide compounds |
MX2019015881A (en) * | 2017-06-23 | 2020-02-07 | Basf Se | Pesticidal mixtures comprising a pyrazole compound. |
WO2019086678A1 (en) | 2017-11-06 | 2019-05-09 | Basf Se | Indicating soil additives for improving soil water infiltration and/or modulating soil water repellence |
CN111770686A (en) * | 2018-03-07 | 2020-10-13 | 巴斯夫农业化学品有限公司 | Method for increasing resistance of cereal plants |
CN113980990B (en) * | 2021-11-26 | 2022-07-26 | 中国农业科学院生物技术研究所 | Transgenic insect-resistant herbicide-resistant corn and cultivation method thereof |
Family Cites Families (273)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3325503A (en) | 1965-02-18 | 1967-06-13 | Diamond Alkali Co | Polychloro derivatives of mono- and dicyano pyridines and a method for their preparation |
US3296272A (en) | 1965-04-01 | 1967-01-03 | Dow Chemical Co | Sulfinyl- and sulfonylpyridines |
DE3338292A1 (en) | 1983-10-21 | 1985-05-02 | Basf Ag, 6700 Ludwigshafen | 7-AMINO-AZOLO (1,5-A) -PYRIMIDINE AND FUNGICIDES CONTAINING THEM |
CA1249832A (en) | 1984-02-03 | 1989-02-07 | Shionogi & Co., Ltd. | Azolyl cycloalkanol derivatives and agricultural fungicides |
US4761373A (en) | 1984-03-06 | 1988-08-02 | Molecular Genetics, Inc. | Herbicide resistance in plants |
US5304732A (en) | 1984-03-06 | 1994-04-19 | Mgi Pharma, Inc. | Herbicide resistance in plants |
US6211439B1 (en) | 1984-08-10 | 2001-04-03 | Mgi Pharma, Inc | Herbicide resistance in plants |
BR8600161A (en) | 1985-01-18 | 1986-09-23 | Plant Genetic Systems Nv | CHEMICAL GENE, HYBRID, INTERMEDIATE PLASMIDIO VECTORS, PROCESS TO CONTROL INSECTS IN AGRICULTURE OR HORTICULTURE, INSECTICIDE COMPOSITION, PROCESS TO TRANSFORM PLANT CELLS TO EXPRESS A PLANTINIDE TOXIN, PRODUCED BY CULTURES, UNITED BY BACILLA |
NZ217113A (en) | 1985-08-07 | 1988-06-30 | Monsanto Co | Production of eucaryotic plants which are glyphosate resistant, vectors (transformation and expression), chimeric gene and plant cells |
US4940835A (en) | 1985-10-29 | 1990-07-10 | Monsanto Company | Glyphosate-resistant plants |
DE3545319A1 (en) | 1985-12-20 | 1987-06-25 | Basf Ag | ACRYLIC ACID ESTERS AND FUNGICIDES THAT CONTAIN THESE COMPOUNDS |
ES2018274T5 (en) | 1986-03-11 | 1996-12-16 | Plant Genetic Systems Nv | VEGETABLE CELLS RESISTANT TO GLUTAMINE SYNTHETASE INHIBITORS, PREPARED BY GENETIC ENGINEERING. |
CN1050538A (en) | 1986-05-02 | 1991-04-10 | 施托福化学公司 | Fungicidal pyridyl imines composition and Fungicidal method |
EP0256503B1 (en) | 1986-08-12 | 1992-12-02 | Mitsubishi Kasei Corporation | Pyridinecarboxamide derivatives and their use as fungicide |
US5013659A (en) | 1987-07-27 | 1991-05-07 | E. I. Du Pont De Nemours And Company | Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase |
DE3629890A1 (en) | 1986-08-29 | 1988-03-10 | Schering Ag | MICROORGANISMS AND PLASMIDES FOR THE 2,4-DICHLORPHENOXYACETIC ACID (2,4-D) MONOOXIGENASE - FORMATION AND METHOD FOR PRODUCING THIS PLASMIDE AND STEM |
US4731499A (en) | 1987-01-29 | 1988-03-15 | Pioneer Hi-Bred International, Inc. | Hybrid corn plant and seed |
US5689046A (en) | 1987-09-30 | 1997-11-18 | Bayer Aktiengesellschaft | Stilbene synthase gene |
US5128130A (en) | 1988-01-22 | 1992-07-07 | Mycogen Corporation | Hybrid Bacillus thuringiensis gene, plasmid and transformed Pseudomonas fluorescens |
DE68923728T2 (en) | 1988-04-25 | 1996-02-22 | Monsanto Co | Insect-resistant lettuce plants. |
CA1340685C (en) | 1988-07-29 | 1999-07-27 | Frederick Meins | Dna sequences encoding polypeptides having beta-1,3-glucanase activity |
US5169629A (en) | 1988-11-01 | 1992-12-08 | Mycogen Corporation | Process of controlling lepidopteran pests, using bacillus thuringiensis isolate denoted b.t ps81gg |
CA2005658A1 (en) | 1988-12-19 | 1990-06-19 | Eliahu Zlotkin | Insecticidal toxins, genes encoding these toxins, antibodies binding to them and transgenic plant cells and plants expressing these toxins |
DE69034081T2 (en) | 1989-03-24 | 2004-02-12 | Syngenta Participations Ag | Disease resistant transgenic plant |
US5955651A (en) | 1989-05-03 | 1999-09-21 | New York University | Transgenic plants that exhibit enhanced nitrogen assimilation |
GB8910624D0 (en) | 1989-05-09 | 1989-06-21 | Ici Plc | Bacterial strains |
CA2015951A1 (en) | 1989-05-18 | 1990-11-18 | Mycogen Corporation | Novel bacillus thuringiensis isolates active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins |
US6329570B1 (en) | 1989-07-19 | 2001-12-11 | Calgene, Llc | Cotton modification using ovary-tissue transcriptional factors |
ATE121267T1 (en) | 1989-11-07 | 1995-05-15 | Pioneer Hi Bred Int | LARVAE-KILLING LECTINS AND BASED PLANT RESISTANCE AGAINST INSECTS. |
AU628229B2 (en) | 1989-11-10 | 1992-09-10 | Agro-Kanesho Co. Ltd. | Hexahydrotriazine compounds and insecticides |
US5750864A (en) | 1994-06-17 | 1998-05-12 | Epitope, Inc. | Regulated expression of heterologous genes in plants |
US5639949A (en) | 1990-08-20 | 1997-06-17 | Ciba-Geigy Corporation | Genes for the synthesis of antipathogenic substances |
US5633435A (en) | 1990-08-31 | 1997-05-27 | Monsanto Company | Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases |
GB9019736D0 (en) | 1990-09-10 | 1990-10-24 | Univ Leeds Ind Service Ltd | Plant parasitic nematode control |
GB9024323D0 (en) | 1990-11-08 | 1990-12-19 | Ici Plc | Regulation of gene expression |
SE467358B (en) | 1990-12-21 | 1992-07-06 | Amylogene Hb | GENETIC CHANGE OF POTATISE BEFORE EDUCATION OF AMYLOPECT TYPE STARCH |
US5512466A (en) | 1990-12-26 | 1996-04-30 | Monsanto Company | Control of fruit ripening and senescence in plants |
NZ244091A (en) | 1991-08-29 | 1994-10-26 | Zeneca Ltd | Biocidal proteins derived from plants, their manufacture, coding sequences and uses |
JP2828186B2 (en) | 1991-09-13 | 1998-11-25 | 宇部興産株式会社 | Acrylate-based compounds, their preparation and fungicides |
UA48104C2 (en) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Dna fragment including sequence that codes an insecticide protein with optimization for corn, dna fragment providing directed preferable for the stem core expression of the structural gene of the plant related to it, dna fragment providing specific for the pollen expression of related to it structural gene in the plant, recombinant dna molecule, method for obtaining a coding sequence of the insecticide protein optimized for corn, method of corn plants protection at least against one pest insect |
AU2928492A (en) | 1991-11-20 | 1993-06-15 | Mogen International N.V. | A method for obtaining plants with reduced susceptibility to plant-parasitic nematodes |
EP0631629B1 (en) | 1992-03-20 | 2003-12-03 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Fungus-responsive chimaeric gene |
US5409823A (en) | 1992-09-24 | 1995-04-25 | Ciba-Geigy Corporation | Methods for the production of hybrid seed |
DE4317845A1 (en) | 1993-05-28 | 1994-12-01 | Bayer Ag | Deoxyribonucleic acids |
US5824876A (en) | 1993-06-28 | 1998-10-20 | Advanced Technologies (Cambridge) Limited | Plant parasitic nematode control |
ES2093578T1 (en) | 1993-10-06 | 1997-01-01 | Univ New York | TRANSGENIC PLANTS THAT PRESENT IMPROVED ASSIMILATION OF NITROGEN. |
US6864405B1 (en) | 1993-10-06 | 2005-03-08 | New York University | Transgenic plants that exhibit enhanced nitrogen assimilation |
US5608147A (en) | 1994-01-11 | 1997-03-04 | Kaphammer; Bryan J. | tfdA gene selectable markers in plants and the use thereof |
GB9403423D0 (en) | 1994-02-23 | 1994-04-13 | Unilever Plc | Novel exo-(1-4)- beta-D galactanase |
US5859351A (en) | 1994-04-13 | 1999-01-12 | The Regents Of The University Of California | Prf protein and nucleic acid sequences: compositions and methods for plant pathogen resistance |
US5981730A (en) | 1994-04-13 | 1999-11-09 | The General Hospital Corporation | RPS gene family, primers, probes, and detection methods |
US5968828A (en) | 1994-05-19 | 1999-10-19 | Helsinki University Licensing Ltd. Oy | Virus-resistant transgenic plants comprising cells transformed with a polynucleotide encoding a potyviridae P1 protein or P1 protein fragment |
US5576202A (en) | 1994-05-19 | 1996-11-19 | Helsinki University Licensing, Ltd. | Virus-resistant transgenic plants |
US5530195A (en) | 1994-06-10 | 1996-06-25 | Ciba-Geigy Corporation | Bacillus thuringiensis gene encoding a toxin active against insects |
US5571706A (en) | 1994-06-17 | 1996-11-05 | The United States Of America As Represented By The Secretary Of Agriculture | Plant virus resistance gene and methods |
KR970007864B1 (en) | 1994-07-21 | 1997-05-17 | 진로 주식회사 | Process of plant which expressing pip of phytolacca insularis nakai |
US5795753A (en) | 1994-12-08 | 1998-08-18 | Pioneer Hi-Bred International Inc. | Reversible nuclear genetic system for male sterility in transgenic plants |
US5750868A (en) | 1994-12-08 | 1998-05-12 | Pioneer Hi-Bred International, Inc. | Reversible nuclear genetic system for male sterility in transgenic plants |
DE4444708A1 (en) | 1994-12-15 | 1996-06-20 | Basf Ag | Use of auxin-type herbicides for the treatment of transgenic crop plants |
WO1996021032A1 (en) | 1994-12-30 | 1996-07-11 | Asgrow Seed Company | Transgenic plants exhibiting heterologous virus resistance |
US5877403A (en) | 1994-12-30 | 1999-03-02 | Seminis Vegetable Seeds, Inc. | Papaya ringspot virus protease gene |
EP0871739A1 (en) | 1994-12-30 | 1998-10-21 | Seminis Vegetable Seeds, Inc. | Plants resistant to c strains of cucumber mosaic virus |
AU710145B2 (en) | 1995-01-17 | 1999-09-16 | Regents Of The University Of California, The | Procedures and materials for conferring disease resistance in plants |
US5977434A (en) | 1995-01-17 | 1999-11-02 | The Regents Of The University Of California | Procedures and materials for conferring disease resistance in plants |
US5952485A (en) | 1995-01-17 | 1999-09-14 | The Regents Of The University Of California | Procedures and materials for conferring disease resistance in plants |
FR2734842B1 (en) | 1995-06-02 | 1998-02-27 | Rhone Poulenc Agrochimie | DNA SEQUENCE OF A HYDROXY-PHENYL PYRUVATE DIOXYGENASE GENE AND OBTAINING PLANTS CONTAINING A HYDROXY-PHENYL PYRUVATE DIOXYGENASE GENE, TOLERANT TO CERTAIN HERBICIDES |
US5767376A (en) | 1995-06-07 | 1998-06-16 | University Of Hawaii At Manoa | Nucleic acids encoding a papaya ACC synthase gene |
CN1192784A (en) | 1995-06-07 | 1998-09-09 | 先锋高级育种国际公司 | Induction of male sterility in plants by expression of high levels of avidin |
US6046384A (en) | 1995-06-07 | 2000-04-04 | Seminis Vegetable Seeds, Inc. | Papaya ringspot virus NIa protease gene |
US6040496A (en) | 1995-06-30 | 2000-03-21 | Novartis Finance Corporation | Use of translationally altered RNA to confer resistance to maize dwarf mosaic virus and other monocotyledonous plant viruses |
AU710874B2 (en) | 1995-06-30 | 1999-09-30 | Dna Plant Technology Corporation | Delayed ripening tomato plants |
GB9525474D0 (en) | 1995-12-13 | 1996-02-14 | Zeneca Ltd | Antifungal proteins |
WO1997030163A1 (en) | 1996-02-14 | 1997-08-21 | The Governors Of The University Of Alberta | Plants having enhanced nitrogen assimilation/metabolism |
US6084153A (en) | 1996-02-14 | 2000-07-04 | The Governors Of The University Of Alberta | Plants having enhanced nitrogen assimilation/metabolism |
US20020073443A1 (en) | 1996-02-28 | 2002-06-13 | Heifetz Peter B. | Herbicide tolerance achieved through plastid transformation |
US6084164A (en) | 1996-03-25 | 2000-07-04 | Pioneer Hi-Bred International, Inc. | Sunflower seeds with enhanced saturated fatty acid contents |
GB9606906D0 (en) | 1996-04-02 | 1996-06-05 | Zeneca Ltd | Ripening-related dna from melon |
GB9607517D0 (en) | 1996-04-11 | 1996-06-12 | Gene Shears Pty Ltd | The use of DNA Sequences |
HUP0202676A2 (en) | 1996-04-30 | 2002-12-28 | Pioneer Hi-Bred International Inc. | Transgenic plants with enhanced sulfur amino acid content |
DE19619917A1 (en) | 1996-05-17 | 1997-11-20 | Max Planck Gesellschaft | Potato plants with a reduced activity of the cytosolic starch phosphorylase and a changed germination behavior |
US6232528B1 (en) | 1996-06-26 | 2001-05-15 | University Of Florida Research Foundation Incorporated | Disease resistance in vitis |
PL330847A1 (en) | 1996-06-27 | 1999-06-07 | Du Pont | Plant gene of p-hydroxyphenylpyrogronianic dioxygenase |
US5952546A (en) | 1996-06-27 | 1999-09-14 | Dna Plant Technology Corporation | Delayed ripening tomato plants with T-DNA bearing a truncated ACC2 synthase gene |
US5850026A (en) | 1996-07-03 | 1998-12-15 | Cargill, Incorporated | Canola oil having increased oleic acid and decreased linolenic acid content |
DE19650197A1 (en) | 1996-12-04 | 1998-06-10 | Bayer Ag | 3-thiocarbamoylpyrazole derivatives |
US6376754B1 (en) | 1997-03-07 | 2002-04-23 | Asgrow Seed Company | Plants having resistance to multiple herbicides and its use |
US7105724B2 (en) | 1997-04-04 | 2006-09-12 | Board Of Regents Of University Of Nebraska | Methods and materials for making and using transgenic dicamba-degrading organisms |
TW460476B (en) | 1997-04-14 | 2001-10-21 | American Cyanamid Co | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
US20020092041A1 (en) | 1997-08-13 | 2002-07-11 | Pamela C. Ronald | Procedures and materials for conferring disease resistance in plants |
SK284626B6 (en) | 1997-09-18 | 2005-08-04 | Basf Aktiengesellschaft | Benzamidoxim derivatives, intermediate products for preparing them, fungicide compounds containing them and using them as fungicides |
DE19750012A1 (en) | 1997-11-12 | 1999-05-20 | Bayer Ag | Isothiazole carboxamides |
AU1621799A (en) | 1997-12-04 | 1999-06-16 | Dow Agrosciences Llc | Fungicidal compositions and methods, and compounds and methods for the preparation thereof |
AR017831A1 (en) | 1997-12-10 | 2001-10-24 | Pioneer Hi Bred Int | METHOD FOR ALTERING THE COMPOSITION OF AMINO ACIDS OF A NATIVE PROTEIN OF INTEREST, PREPARED PROTEIN, AND POLINUCLEOTIDE |
US7329802B1 (en) | 1998-02-17 | 2008-02-12 | Henry Daniell | Genetic engineering of cotton to increase fiber strength, water absorption and dye binding |
US7041875B1 (en) | 1998-03-18 | 2006-05-09 | Eduardo Blumwald | Genetic engineering salt tolerance in crop plants |
IT1299184B1 (en) | 1998-06-08 | 2000-02-29 | Istituto Agrario Di San Michel | NUCLEOTIDE SEQUENCES OF THE APPLE LRPKM1 GENE, AMINO ACID SEQUENCES AND THEIR USES. |
WO2000004175A1 (en) | 1998-07-14 | 2000-01-27 | Unilever Plc | Methods and composition for modulating flavonoid content |
US6693185B2 (en) | 1998-07-17 | 2004-02-17 | Bayer Bioscience N.V. | Methods and means to modulate programmed cell death in eukaryotic cells |
US6365802B2 (en) | 1998-08-14 | 2002-04-02 | Calgene Llc | Methods for increasing stearate content in soybean oil |
CN1243002C (en) | 1998-11-17 | 2006-02-22 | 组合化学工业株式会社 | Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural bactericides |
IT1303800B1 (en) | 1998-11-30 | 2001-02-23 | Isagro Ricerca Srl | DIPEPTID COMPOUNDS HAVING HIGH FUNGICIDE AND AGRICULTURAL USE. |
EP1018553B1 (en) | 1999-01-08 | 2005-03-30 | Korea Kumho Petrochemical Co. Ltd. | Transgenic plants with divergent SCaM4 or SCaM5 gene to achieve multiple disease resistance |
JP3417862B2 (en) | 1999-02-02 | 2003-06-16 | 新東工業株式会社 | Silica gel highly loaded with titanium oxide photocatalyst and method for producing the same |
AU770077B2 (en) | 1999-03-11 | 2004-02-12 | Dow Agrosciences Llc | Heterocyclic substituted isoxazolidines and their use as fungicides |
WO2000060061A2 (en) | 1999-03-31 | 2000-10-12 | Syngenta Participations Ag | Transgenic plant resistant to mycotoxins and methods |
US6346655B1 (en) | 1999-03-31 | 2002-02-12 | Syngenta Participations Ag | Trichothecne-Resistant transgenic plants |
US6586617B1 (en) | 1999-04-28 | 2003-07-01 | Sumitomo Chemical Takeda Agro Company, Limited | Sulfonamide derivatives |
UA73307C2 (en) | 1999-08-05 | 2005-07-15 | Куміаі Кемікал Індастрі Ко., Лтд. | Carbamate derivative and fungicide of agricultural/horticultural destination |
US6579455B1 (en) | 1999-09-09 | 2003-06-17 | Pti Advanced Filtration | Filter and valve apparatus |
US6472588B1 (en) | 1999-09-10 | 2002-10-29 | Texas Tech University | Transgenic cotton plants with altered fiber characteristics transformed with a sucrose phosphate synthase nucleic acid |
WO2001021821A2 (en) | 1999-09-17 | 2001-03-29 | Aventis Cropscience N.V. | Insect-resistant rice plants |
JP2001095406A (en) | 1999-09-30 | 2001-04-10 | Japan Tobacco Inc | Creation of male sterile plants |
AU3596701A (en) | 1999-10-13 | 2001-05-08 | Avestha Gengraine Technologies Private Limited | Isolated nucleic acid sequence conferring salt tolerance in rice plant |
US6727411B2 (en) | 1999-12-13 | 2004-04-27 | Ajinomoto Co., Inc. | Method of producing transgenic plants having improved amino acid composition |
DE10021412A1 (en) | 1999-12-13 | 2001-06-21 | Bayer Ag | Fungicidal active ingredient combinations |
US6706952B1 (en) | 1999-12-15 | 2004-03-16 | Syngenta Participations Ag | Arabidopsis gene encoding a protein involved in the regulation of SAR gene expression in plants |
ATE290785T1 (en) | 2000-01-25 | 2005-04-15 | Syngenta Participations Ag | HERBICIDAL COMPOSITION |
US6376548B1 (en) | 2000-01-28 | 2002-04-23 | Rohm And Haas Company | Enhanced propertied pesticides |
IL167958A (en) | 2000-02-04 | 2010-11-30 | Sumitomo Chemical Co | 2-thio 3-hydroxypyridine derivatives |
US6864362B2 (en) | 2000-03-16 | 2005-03-08 | E. I. Du Pont De Nemours And Company | Hypoallergenic transgenic soybeans |
US6630618B2 (en) | 2000-03-21 | 2003-10-07 | The United States Of America As Represented By The Secretary Of Agriculture | Transgenic plants having non-pathogen induced systemic acquired resistance (SAR) |
ATE476514T1 (en) | 2000-04-18 | 2010-08-15 | Commw Scient Ind Res Org | METHOD FOR MODIFYING COTTON OIL CONTENT |
WO2001092544A1 (en) | 2000-05-30 | 2001-12-06 | University Of Delhi | Regulation of lethal gene expression in plants |
WO2001096584A2 (en) | 2000-06-12 | 2001-12-20 | Akkadix Corporation | Materials and methods for the control of nematodes |
FR2812883B1 (en) | 2000-08-11 | 2002-10-18 | Aventis Cropscience Sa | USE OF HPPD INHIBITORS AS SELECTING AGENTS IN PLANT TRANSFORMATION |
AR030576A1 (en) | 2000-08-25 | 2003-08-27 | Syngenta Participations Ag | INSECTICIDE TOXINS AND NUCLEIC ACID SEQUENCES CODING THEM |
RU2003110962A (en) | 2000-09-18 | 2004-10-20 | Е.И.Дюпон де Немур энд Компани (US) | Pyridinyl amides and imides for use as fungicides |
AU2864002A (en) | 2000-11-17 | 2002-05-27 | Dow Agrosciences Llc | Compounds having fungicidal activity and processes to make and use same |
US6720481B1 (en) | 2001-02-27 | 2004-04-13 | Pioneer Hi-Bred International, Inc. | Canola cultivar 46A42 |
US7154023B2 (en) | 2001-03-08 | 2006-12-26 | The Ohio State University Research Foundation | Transgenic plants with altered levels of phenolic compounds |
MXPA03009323A (en) | 2001-04-11 | 2004-04-18 | Cornell Res Foundation Inc | Nucleic acid molecules relating to papaya ripening. |
JP5034142B2 (en) | 2001-04-20 | 2012-09-26 | 住友化学株式会社 | Plant disease control composition |
US20060157072A1 (en) | 2001-06-08 | 2006-07-20 | Anthony Albino | Method of reducing the harmful effects of orally or transdermally delivered nicotine |
WO2003000906A2 (en) | 2001-06-22 | 2003-01-03 | Syngenta Participations Ag | Plant disease resistance genes |
US7294759B2 (en) | 2001-06-29 | 2007-11-13 | E. I. Du Pont De Nemours And Company | Alteration of oil traits in plants |
DE10136065A1 (en) | 2001-07-25 | 2003-02-13 | Bayer Cropscience Ag | pyrazolylcarboxanilides |
AR037228A1 (en) | 2001-07-30 | 2004-11-03 | Dow Agrosciences Llc | ACID COMPOUNDS 6- (ARIL OR HETEROARIL) -4-AMYNOPYCOLINIC, HERBICIDE COMPOSITION THAT UNDERSTANDS AND METHOD TO CONTROL UNWANTED VEGETATION |
FR2828196A1 (en) | 2001-08-03 | 2003-02-07 | Aventis Cropscience Sa | New iodochromone derivatives, useful for the prevention or cure of plant fungal disorders, especially in cereals, vines, fruits, legumes or ornamental plants |
JP3668736B2 (en) | 2001-08-07 | 2005-07-06 | 独立行政法人農業生物資源研究所 | A novel rice gene that regulates salt stress tolerance |
KR100879693B1 (en) | 2001-08-17 | 2009-01-21 | 상꾜 아그로 가부시키가이샤 | 2-Cyclopropyl-6-methylphenol |
NZ531160A (en) | 2001-08-20 | 2005-12-23 | Nippon Soda Co | Tetrazoyl oxime derivative as active ingredient in agricultural chemical to control plant disease |
US7230167B2 (en) | 2001-08-31 | 2007-06-12 | Syngenta Participations Ag | Modified Cry3A toxins and nucleic acid sequences coding therefor |
AU2002361696A1 (en) | 2001-12-17 | 2003-06-30 | Syngenta Participations Ag | Novel corn event |
GB0130199D0 (en) | 2001-12-17 | 2002-02-06 | Syngenta Mogen Bv | New nematode feeding assay |
US7230168B2 (en) | 2001-12-20 | 2007-06-12 | The Curators Of The University Of Missouri | Reversible male sterility in transgenic plants by expression of cytokinin oxidase |
AU2002354251A1 (en) | 2001-12-21 | 2003-07-09 | Nissan Chemical Industries, Ltd. | Bactericidal composition |
TWI327462B (en) | 2002-01-18 | 2010-07-21 | Sumitomo Chemical Co | Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same |
DE10204390A1 (en) | 2002-02-04 | 2003-08-14 | Bayer Cropscience Ag | Disubstituted thiazolylcarboxanilides |
EP1334979A1 (en) | 2002-02-08 | 2003-08-13 | Kweek-en Researchbedrijf Agrico B.V. | Gene conferring resistance to Phytophthera infestans (late-blight) in Solanaceae |
DE60314600T2 (en) | 2002-03-05 | 2007-12-27 | Syngenta Participations Ag | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES |
WO2004005485A2 (en) | 2002-07-10 | 2004-01-15 | Kansas State University Research Foundation | Compositions and methods for controlling parasitic nematodes |
US7148397B2 (en) | 2002-08-29 | 2006-12-12 | The United States Of America As Represented By The Secretary Of Agriculture | Solanum bulbocastanum late blight resistance gene and use thereof |
GB0227966D0 (en) | 2002-11-29 | 2003-01-08 | Syngenta Participations Ag | Organic Compounds |
FR2848568B1 (en) | 2002-12-17 | 2005-04-15 | Rhobio | CHIMERIC GENE FOR THE EXPRESSION OF HYDROXY-PHENYL PYRUVATE DIOXYGENASE IN TRANSPLASTOMIC PLASTS AND PLANTS COMPRISING SUCH A GENE HERBICIDE TOLERANT |
WO2004083193A1 (en) | 2003-03-17 | 2004-09-30 | Sumitomo Chemical Company, Limited | Amide compound and bactericide composition containing the same |
CN1784495B (en) | 2003-04-09 | 2011-01-12 | 拜尔生物科学公司 | Methods and means for increasing the tolerance of plants to stress conditions |
CN1812811A (en) | 2003-06-04 | 2006-08-02 | 维克多烟草公司 | Method of reducing the harmful effects of orally or transdermally delivered nicotine |
IL157538A0 (en) | 2003-08-21 | 2004-03-28 | Bar Ilan Res & Dev Company Ltd | Plant resistant to cytoplasm-feeding parasites |
DE602004029089D1 (en) | 2003-10-02 | 2010-10-21 | Monsanto Technology Llc | STACKING CHARACTERISTICS TO IMPROVE COMMERCIAL PLANTS IN TRANSGENIC PLANTS |
HUP0303778A2 (en) | 2003-11-19 | 2007-06-28 | Mezoegazdasagi Biotechnologiai | Plant with increased drought resistance |
TWI355894B (en) | 2003-12-19 | 2012-01-11 | Du Pont | Herbicidal pyrimidines |
US7317146B2 (en) | 2003-12-31 | 2008-01-08 | Pioneer Hi-Bred International, Inc. | Production of cereal grain with reduced starch granule size and uses thereof |
WO2005073165A1 (en) | 2004-01-28 | 2005-08-11 | Mitsui Chemicals, Inc. | Amide derivatives, process for production of the same, and method for application thereof as insecticide |
AR047598A1 (en) | 2004-02-10 | 2006-01-25 | Monsanto Technology Llc | TRANSGENIZED CORN SEED WITH GREATER AMINO ACID CONTENT |
CA2553715C (en) | 2004-02-18 | 2012-08-28 | Ishihara Sangyo Kaisha, Ltd. | Anthranilamide compounds, process for their production and pesticides containing them |
US7622301B2 (en) | 2004-02-24 | 2009-11-24 | Basf Plant Science Gmbh | Compositions and methods using RNA interference for control of nematodes |
BRPI0508337A (en) | 2004-03-10 | 2007-07-24 | Basf Ag | compounds, processes for their preparation, fungicidal agent, seed, and process for combating phytopathogenic harmful fungi |
BRPI0508281B1 (en) | 2004-03-10 | 2015-04-14 | Basf Ag | Compounds, process for their preparation, fungicidal agent, seed, and process for combating phytopathogenic harmful fungi |
US7838733B2 (en) | 2004-04-30 | 2010-11-23 | Dow Agrosciences Llc | Herbicide resistance genes |
US20080020999A1 (en) | 2004-06-03 | 2008-01-24 | Klapproth Michael C | Fungicidal Mixtures Of Amidinylphenyl Compounds |
BRPI0512118A (en) | 2004-06-18 | 2008-02-06 | Basf Ag | compound, process to combat harmful fungi, and fungicidal agent |
BRPI0512121A (en) | 2004-06-18 | 2008-02-06 | Basf Ag | compound, process for combating harmful fungi, fungicidal agent, and use of compounds |
CN101128588A (en) | 2004-08-11 | 2008-02-20 | 孟山都技术有限公司 | Enhanced zein reduction in transgenic corn seed |
GB0418048D0 (en) | 2004-08-12 | 2004-09-15 | Syngenta Participations Ag | Method for protecting useful plants or plant propagation material |
US7659444B2 (en) | 2004-08-13 | 2010-02-09 | Basf Plant Science Gmbh | Compositions and methods using RNA interference for control of nematodes |
WO2006042145A2 (en) | 2004-10-07 | 2006-04-20 | Cornell Research Foundation, Inc. | THE RICE BACTERIAL BLIGHT DISEASE RESISTANCE GENE xa5 |
CN101056534B (en) | 2004-10-13 | 2012-10-10 | 乔治亚大学研究基金会公司 | Nematode resistant transgenic plants |
AU2005296529B2 (en) | 2004-10-20 | 2011-03-24 | Ihara Chemical Industry Co., Ltd. | 3-triazolylphenyl sulfide derivative and insecticide/acaricide/nematicide containing the same as active ingredient |
AR051690A1 (en) | 2004-12-01 | 2007-01-31 | Basf Agrochemical Products Bv | MUTATION INVOLVED IN THE INCREASE OF TOLERANCE TO IMIDAZOLINONE HERBICIDES IN PLANTS |
US20080229448A1 (en) | 2004-12-20 | 2008-09-18 | Mendel Biotechnology, Inc. | Plant Stress Tolerance from Modified Ap2 Transcription Factors |
DE502006001074D1 (en) | 2005-02-16 | 2008-08-21 | Basf Se | 5-ALKOXYALKYL-6-ALKYL-7-AMINO-AZOLOPYRIMIDINE, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE FOR THE CONTROL OF HARMFUL FUNGI AND THE MEDIUM CONTAINING THE SAME |
DE102005007160A1 (en) | 2005-02-16 | 2006-08-24 | Basf Ag | Pyrazolecarboxylic acid anilides, process for their preparation and compositions containing them for controlling harmful fungi |
DE102005008021A1 (en) | 2005-02-22 | 2006-08-24 | Bayer Cropscience Ag | New spiroketal-substituted cyclic ketoenol compounds used for combating animal parasites, undesired plant growth and/or undesired microorganisms |
DE102005009458A1 (en) | 2005-03-02 | 2006-09-07 | Bayer Cropscience Ag | pyrazolylcarboxanilides |
US20060225152A1 (en) | 2005-04-04 | 2006-10-05 | E.I. Du Pont De Nemours And Company | Polynucleotides and methods for making plants resistant to fungal pathogens |
US7417181B2 (en) | 2005-04-07 | 2008-08-26 | The Samuel Roberts Noble Foundation | Plants with increased phosphorous uptake |
AP2344A (en) | 2005-07-07 | 2011-12-28 | Basf Ag | N-Thio-anthranilamid compounds and their use as pesticides. |
WO2007013150A1 (en) | 2005-07-27 | 2007-02-01 | Mitsui Chemicals, Inc. | Pest control composition |
AU2005336142B2 (en) | 2005-09-06 | 2011-09-01 | Stichting Wageningen Research | A transgenic plant having enhanced drought tolerance |
EP2251336A1 (en) | 2005-10-14 | 2010-11-17 | Sumitomo Chemical Company, Limited | Hydrazide compounds as intermediates of pesticides |
TWI396682B (en) | 2006-01-13 | 2013-05-21 | Dow Agrosciences Llc | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides |
WO2007090624A2 (en) | 2006-02-09 | 2007-08-16 | Syngenta Participations Ag | A method of protecting a plant propagation material, a plant, and/or plant organs |
AR059433A1 (en) | 2006-02-10 | 2008-04-09 | Monsanto Technology Llc | IDENTIFICATION AND USE OF WHITE GENES FOR THE CONTROL OF PARASITE PLANT NEMATODES |
DE102006015197A1 (en) | 2006-03-06 | 2007-09-13 | Bayer Cropscience Ag | Active ingredient combination with insecticidal properties |
US20070214515A1 (en) | 2006-03-09 | 2007-09-13 | E.I.Du Pont De Nemours And Company | Polynucleotide encoding a maize herbicide resistance gene and methods for use |
WO2007101369A1 (en) | 2006-03-09 | 2007-09-13 | East China University Of Science And Technology | Preparation method and use of compounds having high biocidal activities |
US20080092255A1 (en) | 2006-03-27 | 2008-04-17 | Edgerton Michael D | Methods of producing and using cold temperature tolerant plants, seeds, and crops |
WO2008034648A1 (en) | 2006-04-05 | 2008-03-27 | Metanomics Gmbh | Process for the production of a fine chemical |
US20070261136A1 (en) | 2006-05-02 | 2007-11-08 | Pioneer Hi-Bred International, Inc. | High Amylopectin Maize |
WO2007131699A2 (en) | 2006-05-12 | 2007-11-22 | Bayer Bioscience N.V. | Novel stress-related microrna molecules and uses thereof |
US7632982B2 (en) | 2006-06-23 | 2009-12-15 | Monsanto Technology Llc | Drought responsive promoters HVA22e and PLDδ identified from Arabidopsis thaliana |
CN101511865A (en) | 2006-08-10 | 2009-08-19 | 巴斯福植物科学有限公司 | Method of increasing resistance against soybean rust in transgenic plants |
DE102006057036A1 (en) | 2006-12-04 | 2008-06-05 | Bayer Cropscience Ag | New biphenyl substituted spirocyclic ketoenol derivatives useful for the manufacture of herbicides and for combating parasites |
CA2674499A1 (en) | 2007-02-06 | 2008-08-14 | Basf Plant Science Gmbh | Use of alanine racemase genes to confer nematode resistance to plants |
MX2009007608A (en) | 2007-02-06 | 2009-07-27 | Basf Plant Science Gmbh | Compositions and methods using rna interference for control of nematodes. |
US7432421B2 (en) | 2007-02-28 | 2008-10-07 | Pioneer Hi-Bred International, Inc. | Soybean variety XB30E07 |
WO2008134969A1 (en) | 2007-04-30 | 2008-11-13 | Sinochem Corporation | Benzamide compounds and applications thereof |
HUE035062T2 (en) | 2008-01-15 | 2018-05-02 | Bayer Ip Gmbh | Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance |
TW201002208A (en) | 2008-04-07 | 2010-01-16 | Bayer Cropscience Ag | Combinations of biological control agents and insecticides or fungicides |
CN101333213B (en) | 2008-07-07 | 2011-04-13 | 中国中化股份有限公司 | 1-substituted pyridyl-pyrazol acid amide compounds and use thereof |
BRPI0916218B1 (en) | 2008-07-17 | 2018-11-27 | Bayer Cropscience Ag | heterocyclic compounds as pesticides compositions |
US8853440B2 (en) * | 2008-08-13 | 2014-10-07 | Mitsui Chemicals Agro, Inc. | Method for producing amide derivative |
US8686044B2 (en) * | 2008-08-13 | 2014-04-01 | Mitsui Chemicals Agro, Inc. | Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative |
CN102119143B (en) | 2008-08-13 | 2017-07-21 | 三井化学Agro株式会社 | Amide derivatives, the noxious organism control agent containing the amide derivatives and its application method |
TWI607996B (en) | 2008-09-24 | 2017-12-11 | 巴地斯顏料化工廠 | Pyrazole compounds for controlling invertebrate pests |
CN101715774A (en) | 2008-10-09 | 2010-06-02 | 浙江化工科技集团有限公司 | Preparation and use of compound having insecticidal activity |
BRPI0914500A2 (en) * | 2008-10-21 | 2015-08-11 | Basf Se | "pest control method, method of increasing plant health of a cultivated plant, seed of a cultivated plant, composition, method of producing an agricultural product, use of a composition and uses of a pesticide" |
AR075467A1 (en) * | 2008-10-22 | 2011-04-06 | Basf Se | USE OF OXIDASE PROTOPORPHYRINOGEN INHIBITORS IN CULTIVATED PLANTS |
WO2010046463A1 (en) | 2008-10-23 | 2010-04-29 | Basf Se | Use of selected insecticides on cultivated plants |
CN101747276B (en) | 2008-11-28 | 2011-09-07 | 中国中化股份有限公司 | Ether compound with nitrogenous quinary alloy and application thereof |
GB0823002D0 (en) | 2008-12-17 | 2009-01-28 | Syngenta Participations Ag | Isoxazoles derivatives with plant growth regulating properties |
CN101747320B (en) | 2008-12-19 | 2013-10-16 | 华东理工大学 | Dialdehyde-built nitrogen or oxygen-containing heterocyclic compound with insect-killing activity and preparation method |
UA107791C2 (en) | 2009-05-05 | 2015-02-25 | Dow Agrosciences Llc | Pesticidal compositions |
MA33331B1 (en) | 2009-05-06 | 2012-06-01 | Syngenta Participations Ag | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN COMBATING PESTS |
WO2011028657A1 (en) | 2009-09-01 | 2011-03-10 | Dow Agrosciences Llc | Synergistic fungicidal compositions containing a 5-fluoropyrimidine derivative for fungal control in cereals |
CN102093389B (en) | 2009-12-09 | 2014-11-19 | 华东理工大学 | Duplex and oxygen bridge heterlcyclic ring anabasine compound and preparation method thereof |
KR101719854B1 (en) | 2009-12-22 | 2017-03-24 | 미쓰이가가쿠 아그로 가부시키가이샤 | Plant disease control composition and method for controlling plant diseases by applying the composition |
WO2011085575A1 (en) | 2010-01-15 | 2011-07-21 | 江苏省农药研究所股份有限公司 | Ortho-heterocyclyl formanilide compounds, their synthesis methods and use |
CN102126994B (en) | 2010-01-19 | 2014-07-09 | 中化蓝天集团有限公司 | Benzophenone hydrazone derivative and preparation method and application thereof |
CN102740695B (en) | 2010-01-29 | 2015-04-22 | 三井化学Agro株式会社 | Composition for control of animal parasites, and method for control of animal parasites |
JP2011157296A (en) | 2010-01-29 | 2011-08-18 | Mitsui Chemicals Agro Inc | Pest-controlling composition |
JP2011157295A (en) | 2010-01-29 | 2011-08-18 | Mitsui Chemicals Agro Inc | Insect damage-controlling composition for plant seed, and method for preventing insect damage |
JP2011157294A (en) | 2010-01-29 | 2011-08-18 | Mitsui Chemicals Agro Inc | Pest-controlling composition |
MY162552A (en) | 2010-04-28 | 2017-06-15 | Sumitomo Chemical Co | Plant disease control composition and its use |
CA2800369C (en) | 2010-05-31 | 2018-07-10 | Basf Se | Method for increasing the health of a plant |
CN103119036B (en) | 2010-06-28 | 2018-05-08 | 拜耳知识产权有限责任公司 | Heterocyclic compound as insecticide |
CA2808144C (en) | 2010-08-31 | 2019-01-22 | Meiji Seika Pharma Co., Ltd. | Amine derivatives as pest control agents |
CN101935291B (en) | 2010-09-13 | 2013-05-01 | 中化蓝天集团有限公司 | Cyano phthalic diamide compounds, preparation method thereof and use thereof as agricultural chemical pesticide |
CN101967139B (en) | 2010-09-14 | 2013-06-05 | 中化蓝天集团有限公司 | Fluoro methoxylpyrazole-containing o-formylaminobenzamide compound, synthesis method and application thereof |
BR112013014913A2 (en) | 2010-12-20 | 2016-07-19 | Basf Se | pesticide mixtures, pesticidal or parasiticidal composition, method to protect vegetables from insect attack or infestation, to control insects, to control harmful phytopathogenic fungi, to protect vegetables from harmful phytopathogenic fungi, to protect material propagation of plants, for the protection of animals against parasitic infestation or infection, for the treatment of parasites infected or infected with |
RS54848B1 (en) | 2011-04-21 | 2016-10-31 | Basf Se | Novel pesticidal pyrazole compounds |
EP2532233A1 (en) | 2011-06-07 | 2012-12-12 | Bayer CropScience AG | Active compound combinations |
WO2013003977A1 (en) | 2011-07-01 | 2013-01-10 | 合肥星宇化学有限责任公司 | Compound of 2,5-disubstituted-3-nitroimino-1,2,4-triazoline and preparation method and use as pesticide thereof |
KR101641800B1 (en) | 2011-07-13 | 2016-07-21 | 바스프 아그로 비.브이. | Fungicidal substituted 2-[2-halogenalkyl-4-(phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds |
WO2013010862A1 (en) | 2011-07-15 | 2013-01-24 | Basf Se | Fungicidal alkyl-substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds |
AR087516A1 (en) | 2011-08-12 | 2014-03-26 | Basf Se | N-TIO-ANTRANILAMIDE COMPOUNDS AND THEIR USES AS PESTICIDES |
CN103827103A (en) | 2011-08-12 | 2014-05-28 | 巴斯夫欧洲公司 | N-thio-anthranilamide compounds and their use as pesticides |
JP6005652B2 (en) | 2011-09-26 | 2016-10-12 | 日本曹達株式会社 | Agricultural / horticultural fungicide composition |
AU2012317415B2 (en) | 2011-09-29 | 2016-08-25 | Mitsui Chemicals Crop & Life Solutions, Inc. | Production method for 4, 4-difluoro-3,4-dihydroisoquinoline derivative |
WO2013050317A1 (en) | 2011-10-03 | 2013-04-11 | Syngenta Limited | Polymorphs of an isoxazoline derivative |
TWI577286B (en) | 2011-10-13 | 2017-04-11 | 杜邦股份有限公司 | Solid forms of nematocidal sulfonamides |
ES2590466T7 (en) | 2011-12-21 | 2018-05-22 | Basf Se | Use of strobilurin-type compounds to combat phytopathogenic fungi resistant to Qo inhibitors |
PE20190346A1 (en) | 2012-02-27 | 2019-03-07 | Bayer Ip Gmbh | ACTIVE COMPOUND COMBINATIONS |
CA2864993C (en) | 2012-02-29 | 2020-03-24 | Meiji Seika Pharma Co., Ltd. | Pest control composition including novel iminopyridine derivative |
US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
JP6107377B2 (en) | 2012-04-27 | 2017-04-05 | 住友化学株式会社 | Tetrazolinone compounds and uses thereof |
MX351463B (en) | 2012-08-31 | 2017-10-16 | Zoetis Services Llc | Crystalline forms of 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(tr ifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'h-spiro[azetidine-3,1 '-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone. |
US20150250174A1 (en) * | 2012-10-01 | 2015-09-10 | Basf Se | Use of n-thio-anthranilamide compounds on cultivated plants |
WO2014090918A1 (en) | 2012-12-13 | 2014-06-19 | Novartis Ag | Process for the enantiomeric enrichment of diaryloxazoline derivatives |
WO2014119752A1 (en) * | 2013-01-31 | 2014-08-07 | 三井化学アグロ株式会社 | Condensed cyclic pyrimidine compound, and noxious organism control agent comprising same |
CN105121416B (en) | 2013-02-14 | 2018-12-04 | 日产化学工业株式会社 | The crystalline polymorphic form and its manufacturing method of isoxazoline substituted benzamide compound |
TWI652014B (en) | 2013-09-13 | 2019-03-01 | 美商艾佛艾姆希公司 | Heterocyclic substituted bicycloazole insecticide |
EA201600326A1 (en) | 2013-10-18 | 2016-10-31 | Басф Агрокемикэл Продактс Б.В. | APPLICATION OF PESTICIDAL ACTIVE DERIVATIVE CARBOXAMIDE IN METHODS OF APPLICATION AND TREATMENT OF SEEDS AND SOIL |
MX2016005028A (en) | 2013-10-18 | 2016-10-26 | Basf Agrochemical Products Bv | Insecticidal active mixtures comprising carboxamide compound. |
KR102310373B1 (en) | 2013-10-18 | 2021-10-08 | 바스프아그로케미칼 프로덕츠 비.브이. | Agricultural mixtures comprising carboxamide compound |
CR20160397A (en) * | 2014-01-31 | 2016-10-27 | Basf Se | PIRAZOLES FOR THE CONTROL OF INVERTEBRATE PESTS |
AR099677A1 (en) * | 2014-03-07 | 2016-08-10 | Sumitomo Chemical Co | FUSION HETEROCYCLIC COMPOUND AND ITS USE FOR PEST CONTROL |
WO2016059240A1 (en) * | 2014-10-16 | 2016-04-21 | Basf Se | Method and pesticidal mixtures for controlling pentatomidae pests |
JP2015131815A (en) * | 2015-02-07 | 2015-07-23 | 住友化学株式会社 | Plant disease control composition and use thereof |
AU2016231152A1 (en) | 2015-03-11 | 2017-09-28 | Basf Agrochemical Products B.V. | Pesticidal mixture comprising a carboxamide compound and a biopesticide |
MX2017013395A (en) | 2015-04-17 | 2018-06-13 | Basf Agrochemical Products Bv | Method for controlling non-crop pests. |
JP2015166386A (en) | 2015-06-05 | 2015-09-24 | 住友化学株式会社 | Pest control method in soybean |
JP2015199758A (en) * | 2015-06-15 | 2015-11-12 | 住友化学株式会社 | Composition for agricultural chemicals and method for promoting plant growth |
-
2016
- 2016-04-06 WO PCT/EP2016/057502 patent/WO2016162371A1/en active Application Filing
- 2016-04-06 US US15/563,120 patent/US11064696B2/en active Active
- 2016-04-06 CA CA2980505A patent/CA2980505A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US11064696B2 (en) | 2021-07-20 |
CA2980505A1 (en) | 2016-10-13 |
WO2016162371A1 (en) | 2016-10-13 |
US20180199570A1 (en) | 2018-07-19 |
BR112017021450A2 (en) | 2018-07-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP3601298B1 (en) | Process for preparing chiral 2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium compounds | |
US11064696B2 (en) | Use of an insecticidal carboxamide compound against pests on cultivated plants | |
CN108779121A (en) | Dicyclic compound | |
WO2016038067A1 (en) | Use of afidopyropene in genetically modified plants | |
CN106795178A (en) | Substituted pyrimidines compound for preventing and treating animal pest | |
CN107428741A (en) | The cyclic compound substituted by fused ring system | |
CN105939999A (en) | Pyrazoles for controlling invertebrate pests | |
CN107108493A (en) | The oxazoline compound replaced by carbocyclic fused member ring systems | |
US20190082696A1 (en) | Method for controlling pests of plants | |
US11076600B2 (en) | Mixtures of cis-jasmone and bacillus amyloliquefaciens | |
JP7433244B2 (en) | Mixtures containing benzpyrimoxane and oxazosulfil and methods of use and application thereof | |
WO2016091674A1 (en) | Use of cyclaniliprole on cultivated plants | |
EP3628157A1 (en) | Method of controlling insecticide resistant insects and virus transmission to plants | |
CN108699075A (en) | Spirocyclic derivatives | |
CN108137537A (en) | The imino-compound with 2- chlorine pyrimidine -5- base substituent groups as nuisance control agent | |
US11297837B2 (en) | Pesticidally activi mixtures comprising anthranilamide compounds | |
ES2812779T3 (en) | Compositions containing cis-jasmone and Bacillus amyloliquefaciens | |
CN115443267A (en) | Pesticidal compounds | |
CN116234444A (en) | Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof | |
WO2016030108A1 (en) | Use of chlorfenapyr and teflubenzuron on genetically modified plants | |
TW202012418A (en) | Pyrimidinium compounds and their mixtures for combating animal pests | |
WO2018055479A1 (en) | Use of pyripyropene compounds for reducing viral transmission | |
WO2016034352A1 (en) | Use of n-thio-anthranilamide compounds on cultivated plants | |
WO2016146586A1 (en) | Use of cyclaniliprole on cultivated plants | |
BR112017021450B1 (en) | PEST CONTROL METHODS, PLANT HEALTH IMPROVEMENT METHOD AND COATED SEED |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FEPP | Fee payment procedure |
Free format text: ENTITY STATUS SET TO UNDISCOUNTED (ORIGINAL EVENT CODE: BIG.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
|
AS | Assignment |
Owner name: BASF SE, GERMANY Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SIKULJAK, TATJANA;REINHARD, ROBERT;DAESCHNER, KLAUS;SIGNING DATES FROM 20170802 TO 20170808;REEL/FRAME:043838/0890 Owner name: BASF CORPORATION, NEW JERSEY Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:AREVALO, ALEJANDRO;REEL/FRAME:043839/0004 Effective date: 20170807 |
|
AS | Assignment |
Owner name: BASF AGROCHEMICAL PRODUCTS B.V., NETHERLANDS Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BASF SE;REEL/FRAME:044147/0877 Effective date: 20171113 Owner name: BASF AGROCHEMICAL PRODUCTS B.V., NETHERLANDS Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BASF CORPORATION;REEL/FRAME:044146/0960 Effective date: 20171106 |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: NON FINAL ACTION MAILED |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: RESPONSE TO NON-FINAL OFFICE ACTION ENTERED AND FORWARDED TO EXAMINER |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: FINAL REJECTION MAILED |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: RESPONSE AFTER FINAL ACTION FORWARDED TO EXAMINER |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: DOCKETED NEW CASE - READY FOR EXAMINATION |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: RESPONSE TO EX PARTE QUAYLE ACTION ENTERED AND FORWARDED TO EXAMINER |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: NOTICE OF ALLOWANCE MAILED -- APPLICATION RECEIVED IN OFFICE OF PUBLICATIONS |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: PUBLICATIONS -- ISSUE FEE PAYMENT RECEIVED |
|
STPP | Information on status: patent application and granting procedure in general |
Free format text: PUBLICATIONS -- ISSUE FEE PAYMENT VERIFIED |
|
STCF | Information on status: patent grant |
Free format text: PATENTED CASE |