US20180162579A1 - Aseptic filling bottle - Google Patents

Aseptic filling bottle Download PDF

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Publication number
US20180162579A1
US20180162579A1 US15/574,923 US201615574923A US2018162579A1 US 20180162579 A1 US20180162579 A1 US 20180162579A1 US 201615574923 A US201615574923 A US 201615574923A US 2018162579 A1 US2018162579 A1 US 2018162579A1
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US
United States
Prior art keywords
bottle
center
ground contact
aseptic filling
dome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US15/574,923
Other languages
English (en)
Inventor
Tatsuki Kado
Shinya Ito
Naoya OGASAWARA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Holdings Ltd
Original Assignee
Suntory Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57320284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US20180162579(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Suntory Holdings Ltd filed Critical Suntory Holdings Ltd
Assigned to SUNTORY HOLDINGS LIMITED reassignment SUNTORY HOLDINGS LIMITED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ITO, SHINYA, KADO, TATSUKI, OGASAWARA, Naoya
Publication of US20180162579A1 publication Critical patent/US20180162579A1/en
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/02—Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0223—Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by shape
    • B65D1/0261—Bottom construction
    • B65D1/0284—Bottom construction having a discontinuous contact surface, e.g. discrete feet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/02—Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2501/00—Containers having bodies formed in one piece
    • B65D2501/0009—Bottles or similar containers with necks or like restricted apertures designed for pouring contents
    • B65D2501/0018—Ribs
    • B65D2501/0036—Hollow circonferential ribs

Definitions

  • the present invention relates to an aseptic filling bottle having a mouth portion, a shoulder portion, a body portion and a bottom portion.
  • an aseptic filling method of filing liquid in a bottle under a sterilized state As a method of filling liquid in a plastic bottle, there is known an aseptic (sterilized) filling method of filing liquid in a bottle under a sterilized state. With this aseptic filling method, it is possible to prevent the plastic bottle from being exposed to a high temperature. For this reason, an aseptic filling bottle filled by the aseptic filling method (to be referred to as an “aseptic filling bottle” hereinafter) may have only low heat resistance, thus allowing the bottle to be formed thin and light.
  • Patent Document 1 proposes a bottle capable of suppressing buckling of its bottom portion by providing a dome-shaped recess at the center of a center portion of the bottom portion, with the recess intruding the bottle interior.
  • a plastic bottle filled with contents is to be stored not only at a room temperature or a lowered temperature, but may also be stored under freezing in order to store its contents under its frozen state.
  • expansion of the contents occurs due to freezing, which may cause buckling of the bottom portion.
  • this problem appears conspicuously in an aseptic filing bottle which fails to take expansion/contraction of inside air into its designing consideration. In the worst case, not only occurrence of the buckling, but also rupture of the bottle is conceivable.
  • a force applied to the bottom portion due to expansion of contents is greater than a force applied to the bottom portion due to rise of inside pressure caused by carbonate bubbling.
  • the bottle of Patent Document 1 had a strength to such a degree to be able to suppress the buckling at the time of filling of carbonated drink, but not to such a degree as to suppress the buckling due to expansion of contents stored under frozen state.
  • the arrangement such as that of Patent Document 1 is implemented, there would arise also difficulty in consideration of aesthetic aspect and desirable weight reduction of the bottle.
  • an aseptic filling bottle has not been positively used for freeze storage.
  • an aseptic filling bottle having a mouth portion, a shoulder portion, a body portion and a bottom portion;
  • the bottom portion includes a ground contact portion that comes into contact with a mounting surface, a center portion that progressively intrudes interior of the bottle as it extends radially inwards from the ground contact portion, and a dome portion that is provided at a center of the center portion to intrude the interior of the bottle further than the center portion;
  • a circumferential edge of the dome portion side of the center portion has an intrusion height into the bottle interior, which height is higher than a half the height from the ground contact portion to a boundary between the body portion and the bottom portion.
  • the present inventors found that rather than forming only the center of the center portion in the dome-shape intruding the bottle interior, an arrangement of keeping such dome-shape portion and also configuring the whole center portion from the circumferential edge to the ground contact portion to progressively intrude the bottle interior as it extends radially inwards, can achieve further increase of the strength of the bottle bottom portion.
  • the present inventors further found that the strength increasing effect can be even enhanced by an arrangement of setting the maximal intrusion height of the center portion, i.e. the intrusion height of the circumferential edge of the dome portion side, into the bottle interior higher than a half the height of the bottom portion.
  • the strength of the bottom portion can be increased effectively.
  • a half the height of the bottom portion namely, the height up to the boundary between the body portion and the bottom portion
  • the center portion is formed arcuate.
  • the strength of the bottom portion can be further increased since the above arrangement can render the pressure to be applied to the center portion uniform.
  • the buckling phenomenon of the bottom portion under freeze storage can be suppressed in an even more effective manner.
  • a concave groove portion is formed radially from the center portion.
  • the concave groove portion extends from the dome portion to a circumferential edge portion located radially outwards of the ground contact portion.
  • the concave groove portion for bottom portion reinforcement is formed long from the dome portion to the circumferential edge portion, the strength of the bottom portion can be further increased.
  • the concave groove portion has a depth with respect to the ground contact portion which ranges from 2.5 mm to 5.0 mm.
  • the strength of the bottom portion can be further increased.
  • At the body portion at least one recess-like rib which extends circumferentially around its circumference is formed.
  • volumetric expansion of the contents under freeze storage can be absorbed to a certain extent by the recess-like rib provided in the body portion.
  • the force to be applied due to volumetric expansion can be reduced, so that the buckling phenomenon of the bottom portion under freeze storage can be suppressed even more effectively.
  • FIG. 1 is a front view of an aseptic filling bottle
  • FIG. 2 is a bottom view showing a bottom portion of the aseptic filling bottle
  • FIG. 3 is a perspective view showing the bottom portion of the aseptic filling bottle
  • FIG. 4 is a section taken along IV-IV in FIG. 2 .
  • FIG. 5 is a section taken along V-V in FIG. 2 .
  • An aseptic filling bottle 1 relating to this embodiment includes a mouth portion 2 , a shoulder portion 4 , a body portion 5 and a bottom portion 6 .
  • the bottom portion 6 includes a ground contact portion 10 that comes into contact with a mounting surface, a center portion 12 that progressively intrudes interior of the bottle as it extends radially inwards from the ground contact portion 10 toward the center of the bottom portion 6 , and a dome portion 13 that is provided at the center of the center portion 12 to intrude the interior of the bottle further than this center portion 12 .
  • the center portion 12 is configured such that a circumferential edge 12 a of the dome portion side of this center portion 12 has an intrusion height D 1 into the bottle interior, which height is higher than a half D 2 the height from the ground contact portion 10 to the boundary between the body portion 5 and the bottom portion 6 .
  • the aseptic filling bottle (to be referred to simply as “bottle” hereinafter) 1 relating to this embodiment includes, as shown in FIG. 1 , the mouth portion 2 acting as a spout for dispensing liquid and a bottle main portion 3 to be filled with the liquid.
  • the bottle main portion 3 includes the shoulder portion 4 , the body portion 5 and the bottom portion 6 .
  • the shoulder portion 4 designates a portion which is continuous with the mouth portion 2 and which has a progressively increasing diameter as it extends toward the bottom face. In particular, this shoulder portion 4 is comprised of a combination of polygonal “panels” of various shapes.
  • the body portion 4 designates a tubular portion continuous with the shoulder portion 3 .
  • the bottom portion 5 designates a part of the bottle main portion 3 where the circumferential face of this body main portion 3 is progressively decreased in its diameter toward the bottom face.
  • the position of the boundary between the body portion 5 and the bottom portion 6 corresponds to the height position where the diameter of the bottle main portion 3 begins to diminish toward the bottom face.
  • the bottle 1 relating to the present embodiment is a bottle for aseptic (sterilized) filling method of filling liquid in the bottle under a sterilized state.
  • the aseptic filling method it is possible to prevent a plastic bottle from being exposed to a high temperature, so that the bottle 1 may have a low heat resistance, thus allowing it to be configured as a thin and light bottle.
  • the bottle 1 can be formed by integral molding of such main material as polyethylene, polypropylene, polyethyleneterephthalate, etc. using specifically a stretch molding technique such as the biaxial stretch blow molding.
  • the bottle 1 relating to the instant embodiment, as will be described later, is configured to be able to withstand filed contents volumic expansion when liquid filled therein is stored under frozen state.
  • Preferred examples of the contents to be filled in the bottle 1 are non-carbonated drink, which can be stored under frozen state, such as mineral water, tea, soft drink, or fruit juices.
  • carbonated drink or a food product such as sauce can be employed suitably.
  • the body portion 5 consists essentially of a straight body portion 5 a as a “body upper portion”, a constricted portion 5 b and a cushioning portion 5 c as a “body lower portion”.
  • a straight body portion 5 there are formed a plurality of recess-like ribs 7 which extend around the circumferential face of the straight body portion 5 .
  • Each recess-like rib 7 has a shape which is concave on the inner side in the radial direction (the direction extending toward a center axis X of the bottle 1 and along the horizontal direction).
  • the width and depth of the respective recess-like rib 7 are set approximately constant around the entire circumference thereof.
  • These recess-like ribs 7 function as reinforcing ribs for increasing the strength of the lateral face of the bottle 1 and function also as portions for absorbing volumetric expansion of the contents at the time of freeze storage through stretching of the bottle 1 in the vertical upward direction.
  • the constricted portion 5 b is a portion configured to facilitate consumer's gripping of the bottle 1 .
  • the constricted portion 5 b has a shape comprised of combination of polygons having various shapes as seen in its front view. The diameter of the constricted portion 5 b progressively diminishes toward the vertical center position thereof.
  • the cushioning portion 5 c includes a V-shaped recess portion 8 and two small recess portions 9 a , 9 b acting respectively as the recess-like ribs 7 and has a three-stage spring-like arrangement. With this, the cushioning portion 5 c can be elastically deformed in the vertical direction. Therefore, even when a load is applied to the bottle 1 in the vertical direction, this load can be absorbed by elastic deformation of the cushioning portion 5 c , whereby buckling of the bottle 1 can be prevented. Further, the V-shaped recess portion 8 and the small recess portions 9 a , 9 b function also as portions for absorbing, through their deformation, volumetric expansion of the contents liquid at the time of freeze storage. Further, the lower small recess portion 9 b serves also as the boundary between the body portion 5 and the bottom portion 6 .
  • the body portion 5 is configured as described above and in this body portion 5 , the recess-like ribs 7 are formed in the upper portion (straight body portion 5 a ) and the lower portion (the constricted portion 5 b and the cushioning portion 5 c ) of the body portion, respectively.
  • the recess-like ribs 7 can be formed at least one in any chosen position in the body portion 5 .
  • two or more such recess-like ribs 7 will be formed in the body portion 5 .
  • at least one will be formed in the body lower portion and a plurality thereof will be formed in the body upper portion. In the instant embodiment, total of six recess-like ribs 7 are formed in the straight body portion 5 a as the body upper portion.
  • the recess-like rib 7 should have a shape which is concave on the inner side in the radial direction and which extends along the entire circumference.
  • the straight body portion 5 a (the body upper portion) is a portion where an unillustrated label is to be wound.
  • the bottom portion 6 includes the annular ground contact portion 10 which is to be placed in contact with a mounting surface such as that of a desk.
  • the bottom portion 6 further includes a circumferential edge portion 11 which is the portion on the radial outer side of the ground contact portion 10 , the center portion 12 which is the portion on the radial inner side relative to the ground contact portion 10 , and the dome portion 13 that intrudes the bottom interior further than the center portion 12 .
  • the center portion 12 has a shape that progressively intrudes the interior of the bottle 1 (upwards in FIG. 1 ) as it extends radially inwards from the ground contact portion 10 , so that the center portion 12 is formed arcuate from the ground contact portion 10 to the dome portion 13 .
  • circumferential edge 12 a of the dome portion side of the center portion 12 has an intrusion height D 1 into the bottle interior, which height is higher than a half D 2 the height from the ground contact portion 10 to a boundary 6 a between the body portion 5 and the bottom portion 6 .
  • the dome portion 13 has a trapezoidal shape as seen in its vertical section.
  • the bottom portion 6 there are formed, radially equidistantly from the dome portion 13 , a plurality (eight in this embodiment) of concave groove portions 14 that extend from the dome portion 13 to the circumferential edge portion 11 .
  • These concave groove portions 14 provide reinforcement of the strength of the bottom portion 6 .
  • the ground contact portion 10 , the circumferential edge portion 11 and the center portion 12 are sectioned from each other in the circumferential direction (the direction around the center axis X of the bottle 1 ). As shown in FIG.
  • a height position of a circumferential edge portion 11 side end portion 14 a of the respective concave groove portion 14 is set approximately same as a height position of a top portion 13 b of the dome portion 13 .
  • the respective concave groove portion 14 has a depth at its ground contact portion 10 , which depth ranges from 2.5 mm to 5.0 mm. If the depth were smaller than 2.5 mm, this would make it difficult to obtain sufficient strength reinforcement. Whereas, if the depth were greater than 5.0 mm, such excessive depth would impair the aesthetic appearance of the bottom 1 and/or could cause need for design change in the other portions.
  • the strength of the bottom portion 6 is further increased. With these, it has become possible to ensure sufficient strength for the bottom portion 6 to be able to suppress the buckling phenomenon thereof due to volumetric expansion of the contents under freeze storage.
  • the bottom portion 6 is configured to have 0.12 or more weight ratio of this bottom portion 6 relative to the total weight of the bottle 1 .
  • the wall thickness of this bottom portion 6 is positively increased, so that for the bottle as a whole, the strength of the bottom portion 6 can be increased positively or with emphasis.
  • Table 1 shows relationship between the weight ratio of the bottom portion 6 relative to the total bottle weight (bottom portion/total in FIG. 1 ) and presence/absence of rupture/deformation at the time of freeze storage (presence is denoted with X, absence is denoted with ⁇ ).
  • the capacity of the bottle 1 is not particularly limited, but can range from 200 ml (milliliter) to 2 l (litter), which are commonly employed commercially.
  • the bottle 1 is formed with a capacity for filling 550 ml of liquid.
  • its full filling capacity (the capacity for filling liquid up to the mouth portion 2 fully) is set 577 ml.
  • the ratio of weight (g) of the bottom 1 relative to the full filling capacity of the bottom 1 is set to from 0.017 to 0.040 (g/ml).
  • the weight is set to 14.9 g and the ratio of the weight relative to the full filling capacity is set to 0.26 approximately.
  • the aseptic filling bottle 1 if the ratio of the total weight relative to the full filling capacity (the capacity when liquid is filled fully to the mouth portion) exceeds 0.040 (g/ml), such bottle 1 can no longer be called a “thin light bottle” and there will result in less need for strength reinforcement of the bottom portion 6 by setting the weight ratio of the bottom portion relative to the total weight to 0.12 or higher. Conversely, if the weight ratio of the bottom portion relative to the total weight falls below 0.017 (g/ml), this will lead to excessive thinness of the other portion than the bottom portion, such as the body portion, so it will become impossible to secure strength sufficient to prevent rupture due to volumetric expansion.
  • the capacity ratio of the space not filled with the contents liquid (i.e. the margin portion not filled with the contents) relative to the full filling capacity should range 0.12 or less.
  • the capacity ratio of the space not filled with liquid relative to the full filling capacity is set to 0.05 approximately. Namely, when freeze storage situation is contemplated, the volumetric expansion of the contents liquid is to be taken into consideration, so that the space not filled with the contents liquid will be increased in order to absorb such volumetric expansion.
  • the bottle 1 relating to the present embodiment when the contents liquid is filled in the bottle 1 relating to the present embodiment which has the enhanced strength of the bottom portion 6 , there is no need to increase the space not filled with the contents liquid in order to suppress occurrence of buckling of the bottom portion 6 . So, the bottle 1 relating to the present embodiment is suitable for a case of sufficiently filling the contents liquid relative to the full filling capacity. For this reason, as a filled bottle sufficiently filled with contents liquid with the space not filled with the contents liquid relative to the full filling capacity being set to 0.12 or less, the bottle 1 relating to the present embodiment can be used suitably.
  • the body portion 5 is comprised of the straight body portion 5 a , the constricted portion 5 b and the cushioning portion 5 c .
  • the embodiment of the present invention is not limited thereto.
  • the body portion 5 can be comprised of the straight body portion 5 a only.
  • the body portion 5 can be comprised of the straight body portion 5 a , plus either the constricted portion 5 b or the cushioning portion 5 c.
  • the present invention is applicable to e.g. a plastic bottle filled with contents liquid by the aseptic filling method.

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  • Engineering & Computer Science (AREA)
  • Ceramic Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
US15/574,923 2015-05-20 2016-05-19 Aseptic filling bottle Abandoned US20180162579A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015-103127 2015-05-20
JP2015103127A JP7012417B2 (ja) 2015-05-20 2015-05-20 アセプティック充填用ボトル
PCT/JP2016/064848 WO2016186159A1 (ja) 2015-05-20 2016-05-19 アセプティック充填用ボトル

Publications (1)

Publication Number Publication Date
US20180162579A1 true US20180162579A1 (en) 2018-06-14

Family

ID=57320284

Family Applications (1)

Application Number Title Priority Date Filing Date
US15/574,923 Abandoned US20180162579A1 (en) 2015-05-20 2016-05-19 Aseptic filling bottle

Country Status (7)

Country Link
US (1) US20180162579A1 (zh)
EP (1) EP3299306B1 (zh)
JP (1) JP7012417B2 (zh)
CN (1) CN107709175A (zh)
AU (1) AU2016264086B2 (zh)
ES (1) ES2798300T3 (zh)
WO (1) WO2016186159A1 (zh)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210039825A1 (en) * 2018-04-26 2021-02-11 Graham Packaging Company, L.P. Pressurized refill container resistant to standing ring cracking
US10926911B2 (en) 2018-10-15 2021-02-23 Pepsico. Inc. Plastic bottle with base
US20210347102A1 (en) * 2020-05-08 2021-11-11 Orora Packaging Australia Pty Ltd Bottle, and an insert and a mould for making the bottle
US11459140B2 (en) * 2019-12-27 2022-10-04 Yoshino Kogyosho Co., Ltd. Bottle
US20220396408A1 (en) * 2017-08-25 2022-12-15 Graham Packaging Company, L.P. Variable displacement base and container and method of using the same
US20230166882A1 (en) * 2021-11-30 2023-06-01 Pepsico, Inc. Flexible base for aseptic-fill bottles

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7241456B2 (ja) * 2017-03-07 2023-03-17 サントリーホールディングス株式会社 アセプティック充填用ボトル
AU2018283342B2 (en) * 2017-06-12 2023-10-05 Societe Des Produits Nestle S.A. Container bottom base provided with a bi-concave arch
JP2019094128A (ja) * 2017-11-22 2019-06-20 三菱ケミカル株式会社 プラスチックボトル
JP7454914B2 (ja) * 2019-03-29 2024-03-25 サントリーホールディングス株式会社 プラスチックボトル
JP7400380B2 (ja) * 2019-11-18 2023-12-19 東洋製罐株式会社 合成樹脂製容器

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US9327861B2 (en) * 2012-11-27 2016-05-03 Krones Ag Plastic container with reinforced base

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US20090308835A1 (en) * 2008-06-13 2009-12-17 Sidel Participations Container, in particular a bottle, made of a thermoplastic material, provided with a reinforced base
JP2011116429A (ja) * 2009-12-07 2011-06-16 Kirin Brewery Co Ltd 飲料用プラスチック容器及びそれを用いた飲料製品
US9327861B2 (en) * 2012-11-27 2016-05-03 Krones Ag Plastic container with reinforced base

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220396408A1 (en) * 2017-08-25 2022-12-15 Graham Packaging Company, L.P. Variable displacement base and container and method of using the same
US11905095B2 (en) * 2017-08-25 2024-02-20 Co2Pac Limited Variable displacement base and container and method of using the same
US20210039825A1 (en) * 2018-04-26 2021-02-11 Graham Packaging Company, L.P. Pressurized refill container resistant to standing ring cracking
US10926911B2 (en) 2018-10-15 2021-02-23 Pepsico. Inc. Plastic bottle with base
US11459140B2 (en) * 2019-12-27 2022-10-04 Yoshino Kogyosho Co., Ltd. Bottle
US20210347102A1 (en) * 2020-05-08 2021-11-11 Orora Packaging Australia Pty Ltd Bottle, and an insert and a mould for making the bottle
US20230166882A1 (en) * 2021-11-30 2023-06-01 Pepsico, Inc. Flexible base for aseptic-fill bottles

Also Published As

Publication number Publication date
AU2016264086A1 (en) 2017-12-07
ES2798300T3 (es) 2020-12-10
EP3299306B1 (en) 2020-04-29
AU2016264086B2 (en) 2020-04-30
EP3299306A1 (en) 2018-03-28
JP2016216093A (ja) 2016-12-22
JP7012417B2 (ja) 2022-01-28
CN107709175A (zh) 2018-02-16
WO2016186159A1 (ja) 2016-11-24
EP3299306A4 (en) 2019-02-13

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