US20120024862A1 - Before-use mixing container - Google Patents

Before-use mixing container Download PDF

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Publication number
US20120024862A1
US20120024862A1 US13/260,496 US201013260496A US2012024862A1 US 20120024862 A1 US20120024862 A1 US 20120024862A1 US 201013260496 A US201013260496 A US 201013260496A US 2012024862 A1 US2012024862 A1 US 2012024862A1
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United States
Prior art keywords
tube section
movable body
fit
section
opening portion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US13/260,496
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English (en)
Inventor
Tadashi Otsuka
Takashi Fujimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Hanshin Kasei Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd, Hanshin Kasei Kogyo Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Assigned to SENJU PHARMACEUTICAL CO., LTD. reassignment SENJU PHARMACEUTICAL CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: FUJIMOTO, TAKASHI, OTSUKA, TADASHI
Assigned to HANSHIN KASEI CO., LTD., SENJU PHARMACEUTICAL CO., LTD. reassignment HANSHIN KASEI CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: FUJIMOTO, TAKASHI, OTSUKA, TADASHI
Publication of US20120024862A1 publication Critical patent/US20120024862A1/en
Assigned to SENJU PHARMACEUTICAL CO., LTD. reassignment SENJU PHARMACEUTICAL CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HANSHIN KASEI CO., LTD.
Abandoned legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces
    • B65D81/3211—Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/28—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
    • B65D51/2807—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container
    • B65D51/2857—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by displacing or removing an element enclosing it
    • B65D51/2892—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by displacing or removing an element enclosing it the element, e.g. a valve, opening an aperture of the auxiliary container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A61J1/1418—Threaded type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2031—Separating means having openings brought into alignment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093—Containers having several compartments for products to be mixed

Definitions

  • the present invention relates to a before-use mixing container in which two types of medicinal solutions are stored in a separated state in one container, and these are mixed inside the container in use, and extracted for use.
  • a before-use mixing container as a container in which two types of medicinal solutions are stored in a separated state, and these are mixed in the container in use, and extracted for use.
  • a container adopting a system that one medicinal solution and another medicinal solution are respectively contained in a first container body and a second container body in a separated state by use of isolation members in which one member having an opening portion and the other member having an opening portion are slidably fit into each other so that their opening portions do not face each other, and the both opening portions are made to face each other by a sliding operation of the isolation members, to mix the two types of medicinal solutions (refer to Patent Document 1).
  • the present invention has been achieved in consideration of the above-described circumstances. It is a primary object of the present invention to provide a before-use mixing container in which it is possible to perform a mixing operation for two types of medicinal solutions in the container independently of an uncovering operation for a cap or the like.
  • a before-use mixing container including
  • a movable body which has a bottomed cylindrical tube section, a cylindricalled cylindrical inner tube which is consecutively installed upright on an inner side in a circumferential direction from an inner surface of the tube section, that partitions an internal space of the tube section into two upper and lower chambers, and a first opening portion drilled in a ceiling plane of the inner tube, and in which a first medicinal solution is contained in the lower chamber,
  • an adapter which has a hollow cylindrical fit-in tube section which is tightly fit into the upper chamber of the movable body to be assembled so as to be rotatable with respect to the movable body, a partition wall surface which is provided on an inner surface of the fit-in tube section, and is tightly attached to the ceiling plane of the inner tube of the movable body in a state in which the partition wall is assembled to the movable body, and a second opening portion which is drilled in the partition wall surface so as not to overlap the first opening portion, and
  • a container main body which has a lower mouth tube section which is tightly fit into the upper chamber surrounded by an upper surface of the partition wall surface of the adapter and the inner surface of the fit-in tube section, to be assembled so as not to be rotatable with respect to the adapter, and in which a second medicinal solution is contained, and in the container,
  • the container main body when the movable body is relatively rotated with respect to the container main body, the first opening portion of the movable body and the second opening portion of the adapter are overlapped, and the container is capable of mixing the first medicinal solution and the second medicinal solution before use.
  • the fit-in tube section of the adapter is provided with a large diameter section and a small diameter section having circular arc shapes in plan view, and in a state in which the fit-in tube section of the adapter is assembled to the upper chamber of the movable body, the large diameter section and the small diameter section of the fit-in tube section are respectively spaced from the inner surface of the tube section of the movable body to generate gaps, and
  • a vertical line with a height exceeding a spaced distance between the inner surface of the tube section and the large diameter section, and with a height which does not exceed a spaced distance between the inner surface of the tube section and the small diameter section is provided on the inner surface of the tube section of the movable body, and the longitudinal vertical line faces the small diameter section.
  • the container main body and the adapter are assembled so as not to be relatively rotatable, the adapter and the movable body are assembled so as to be relatively rotatable, and the two types of medicinal solutions are mixed by merely relatively rotating the movable body with respect to the container main body, it is possible to perform a mixing operation for the two types of medicinal solutions in the container independently of an uncovering operation for a cap or the like.
  • FIG. 1 is an exploded perspective view of a before-use mixing container showing an embodiment of the present invention.
  • FIG. 2 is a cross-sectional view for explanation of the embodiment shown in FIG. 1 .
  • FIG. 3A is a plan view of a movable body of FIG. 1
  • FIG. 3B is a cross-sectional view taken along line A-A thereof
  • FIG. 3C is a bottom view thereof.
  • FIG. 4A is a plan view of an adapter of FIG. 1
  • FIG. 4B is a front view thereof
  • FIG. 4C is a bottom view thereof
  • FIG. 4D is a cross-sectional view taken along line B-B thereof.
  • FIG. 5A is a front view of a container main body of FIG. 1
  • FIG. 5B is a cross-sectional view taken along line C-C thereof.
  • FIG. 6 are views for explanation in a mixing operation.
  • FIG. 6A is a view showing a state before the mixing operation
  • FIG. 6B is a view showing a state after the mixing operation.
  • FIGS. 1 to 6 show the embodiment of the present invention.
  • a before-use mixing container of the present invention is configured so that a bottom cover, a movable body, an adapter, a container main body, a nozzle, and a cap are integrally assembled.
  • a movable body 1 is an injection-molded part made of synthetic resin. As shown in FIGS. 1 to 3 , the movable body 1 has a cylindrical tube section 11 , an inner ledge 12 installed around so as to be inclined upward to a certain extent, and a Truled short cylindrical inner tube 13 which is consecutively installed upright from the inner ledge 12 , on an inner side in a circumferential direction from an inner surface of the tube section 11 , and a first opening portion 13 b is drilled in a ceiling plane 13 a of the inner tube 13 and a locking groove line 14 is installed around in the inner surface of the lower end opening portion of the tube section 11 .
  • a bottom cover 2 is an injection-molded part made of synthetic resin. As shown in FIGS.
  • a bottom plate 22 blocking up the lower end opening portion of the fit-into tube section 21 is provided at the lower end of a short cylindrical fit-into tube section 21 , and an outer ledge 23 is formed so as to protrude outward in its radial direction from the peripheral edge of the bottom plate 22 .
  • the inner ledge 12 and the inner tube 13 of the movable body 1 compose a partition section that partitions the internal space of the tube section 11 into two upper and lower chambers, and four locking protruding lines 15 are consecutively installed along its circumferential direction, and positioning protruding lines 16 ( 16 a and 16 b ) are provided so as to protrude upward from substantially the central portion of the two locking protruding lines 15 facing each other on the inner surface of the tube section 11 composing the upper chamber above the partition section. Then, a first medicinal solution A is contained in the lower chamber under the partition section.
  • the adapter 3 is an inj ection-molded part made of synthetic resin. As shown in FIGS. 1 , 2 , and 4 , a hollow cylindrical fit-in tube section 31 is a primary member thereof, and the outer diameter of the fit-in tube section 31 is designed in size to have a diameter smaller to a certain extent than the inner diameter of the tube section 11 composing the upper chamber of the movable body 1 .
  • Two locking protruding lines 32 with a length which is approximately the half circle of the fit-in tube section 31 are consecutively installed so as to go around the fit-in tube section 31 on the outer surface of the fit-in tube section 31 , and in the case in which the adapter 3 is tightly fit into the upper chamber of the movable body 1 , these locking protruding lines 32 are locked with the locking protruding lines 15 of the movable body 1 in the axial line direction, thereby making the adapter 3 be assembled so as not to be allowed to be fit and removed and to be rotatable with respect to the movable body 1 .
  • groove portions 32 a and 32 b as gaps between the two locking protruding lines 32 and 32 be respectively fit into the positioning protruding lines 16 a and 16 b of the movable body 1 , and the adapter 3 be pushed downward along the positioning protruding lines 16 a and 16 b.
  • a large number of longitudinal locking vertical lines 33 are provided so as to protrude at regular intervals along the circumferential direction starting from the upper end opening portion on the inner surface of the fit-in tube section 31 , and locking protrusions 34 for locking are provided so as to protrude on the distal ends of the respective longitudinal locking vertical lines 33 .
  • a partition wall surface 35 that partitions the internal space of the fit-in tube section 31 into two upper and lower chambers is provided on the lower side of the locking protrusions 34 , and a short cylindrical airtight cap tube section 36 with a diameter shorter than that of the fit-in tube section 31 is provided upright on the peripheral edge of the partition wall surface 35 , and a second opening portion 35 a is drilled in the inner side of the airtight cap tube section 36 in the partition wall surface 35 .
  • the second opening portion 35 a is disposed so as not to overlap the first opening portion 13 b of the movable body 1 in a state in which the adapter 3 is assembled to the movable body 1 , and is provided at a position at which the second opening portion 35 a overlaps the first opening portion 13 b when the movable body 1 is made to slide with respect to the adapter 3 to rotate around the center of axis. Then, as shown in FIG. 2 , the adapter 3 and the movable body 1 are assembled in a state in which the partition wall surface 35 of the adapter 3 and the fit-in tube section 31 on the side lower than the partition wall surface 35 are fit at the outside of the inner tube 13 of the movable body 1 to be tightly attached in a liquid-tight manner.
  • a container main body 4 is a blow molded article made of synthetic resin. As shown in FIGS. 1 , 2 , and 5 , a second medicinal solution B is contained in the container main body 4 , and a lower mouth tube section 42 is consecutively installed upright via its shoulder portion on the lower end of a cylindrical body section 41 , and an upper mouth tube section 43 on which a screw portion 43 a is carved is consecutively installed upright via the shoulder portion on the upper end of the body section 41 .
  • Four longitudinal locking vertical lines 42 a are provided so as to protrude at regular intervals in the circumferential direction on the outer surface of the lower mouth tube section 42 , and a peripheral protrusion line 42 b is installed around on the outer surface of the lower end of the lower mouth tube section 42 .
  • the nozzle 5 is an injection-molded part made of synthetic resin. As shown in FIGS. 1 and 2 , the nozzle 5 is provided with a short cylindrical airtight cap tube section 51 which is tightly fit into the inner surface of the upper end opening portion of the upper mouth tube section 43 of the container main body 4 , a ceiling plane 52 having an outer ledge 52 a that blocks up the upper end opening portion of the airtight cap tube section 51 , and which is formed so as to protrude outward in a radial direction of the airtight cap tube section, and tightly touches the end face of the upper end opening portion of the upper mouth tube section 43 of the container main body 4 in a liquid-tight manner, and a nozzle section 53 which is formed so as to swell out on the central portion of the ceiling plane 52 .
  • An extracting orifice 53 a is provided in the apical portion of the nozzle section 53 , and the extracting orifice 53 a is configured to have a depressed orifice wall in an inverted circular truncated cone shape from the apical portion of the nozzle section 53 up to the ceiling plane 52 , and is configured to be communicated with the internal space of the airtight cap tube section 51 through an extracting hole 53 b drilled in the lower end of the extracting orifice 53 a of the nozzle section 53 .
  • the cap 6 is an injection-molded part made of synthetic resin. As shown in FIGS. 1 and 2 , the cap 6 is composed of a ceiling plane 61 , an upper tube body 62 in a tapered cylindrical shape whose diameter is extended gently downward from the peripheral edge of the ceiling plane 61 , and a lower tube body 63 in a tapered cylindrical shape whose diameter is extended gently downward via the shoulder portion from the upper tube body 62 .
  • a screw portion 63 a screwed in the screw portion 43 a provided on the upper mouth tube section 43 of the container main body 4 is provided on the inner surface of the lower tube body 63 , and a convex portion 61 a which is tightly attached to the opening edge of the extracting orifice 53 a is provided on the lower surface of the ceiling plane 61 in a liquid-tight manner. Further, an antislip knurl 64 is formed on the outer surface of the lower tube body 63 .
  • the before-use mixing container of the present invention is configured so that the bottom cover 2 , the movable body 1 , the adapter 3 , the container main body 4 , the nozzle 5 , and the cap 6 are integrally assembled, and by use of the ceiling plane 13 a of the inner tube 13 of the movable body 1 and the partition wall surface 35 of the adapter 3 as partition walls, the first medicinal solution A is contained in the lower chamber of the movable body 1 and the second medicinal solution B is contained in the container main body 4 .
  • the movable body 1 and the adapter 3 are assembled so as to be relatively rotatable with respect to each other, and the adapter 3 and the container main body 4 are assembled so as not to be relatively rotatable with respect to each other.
  • a mixing operation for the first medicinal solution A and the second medicinal solution B, and an extraction operation for the mixed liquid are required.
  • the former operation as shown in FIG. 6A , the movable body 1 is rotated in a counterclockwise direction until the first opening portion 13 b overlaps the second opening portion 35 a in a state in which the container is turned upside down while grasping the container main body 4 . Then, as shown in FIG. 6B , the first medicinal solution A contained in the movable body 1 falls into the container main body 4 , thereby achieving mixing of the first medicinal solution A and the second medicinal solution B.
  • the mixed liquid passes through the extracting hole 53 b to be extracted from the extracting orifice 53 a . That is, it is possible to perform a mixing operation for the first medicinal solution A and the second medicinal solution B independently of an extraction operation in the present invention.
  • a large diameter section 31 a and a small diameter section 31 b which are in substantially circular arc shapes in plan view are formed under the locking protruding lines 32 on the outer surface of the fit-in tube section 31 of the adapter 3 , and in a state in which the fit-in tube section 31 of the adapter 3 is assembled to the upper chamber of the movable body 1 , the large diameter section 31 a and the small diameter section 31 b of the fit-in tube section 31 are respectively spaced from the inner surface of the tube section 11 of the movable body 1 to generate gaps. Further, as shown in FIGS.
  • a longitudinal vertical line 17 with a height exceeding a spaced distance between the inner surface of the tube section 11 and the large diameter section 31 a , and with a height which does not exceed a spaced distance between the inner surface of the tube section 11 and small diameter section 31 b is provided so as to protrude on the inner surface of the tube section 11 of the movable body 1 , and this vertical line 17 faces the small diameter section 31 b .
  • protrusion lines 31 c and 31 d are respectively provided in a longitudinal direction in the vicinity of one end side and in the vicinity of the other end side in the circumferential direction of the small diameter section 31 b of the adapter 3
  • locking groove lines 31 e and 31 f are respectively formed between the protrusion line 31 c in the vicinity of the one end side in the circumferential direction of the small diameter section 31 b and the other end side in the circumferential direction of the large diameter section 31 a (the right end portion of the large diameter section in FIG.
  • the movable body 1 is no longer able to be rotated, which terminates the rotation operation. That is, the locking groove lines 31 e and 31 f function as positioning respectively indicating the start and the end of rotation. Moreover, in the present embodiment, since the container is configured so that the first opening portion 13 b and the second opening portion 35 a are overlapped at the end of rotation, it is possible for a user to reliably perform a mixing operation.
  • the synthetic resins used for the above-described respective members are not particularly limited in type.
  • low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), high-density polyethylene (HDPE), polypropylene (PP), and the like may be appropriately combined for use.
  • LDPE or LLDPE is used for the bottom cover 2 and HDPE is used for the movable body 1 in order to improve the liquid-tight performance between the bottom cover 2 and the movable body 1 .
  • HDPE is used for the movable body 1 and PP is used for the adapter 3 in order to improve the liquid-tight performance between the movable body 1 and the adapter 3 .
  • a combination of synthetic resins in which the liquid-tight performance between the respective members is maximized is, from a comprehensive point of view, in the case in which LLDPE is used for the bottom cover, HDPE is used for the movable body, PP is used for the adapter, PP is used for the container main body, LDPE is used for the nozzle, and PP is used for the cap.
  • the ceiling plane 13 a and the partition wall surface 35 are used as partition walls for the first medicinal solution A and the second medicinal solution B, and the first opening portion 13 b and the second opening portion 35 a are respectively provided therein.
  • a plurality of opening portions in the upper and lower partition walls may be provided.
  • test samples (A to D) in which the movable bodies and the container main bodies filled with medicinal solutions were assembled into products were prepared, and the liquid-tight performance between the respective components of these test samples were evaluated.
  • the evaluations of the liquid-tight performance were carried out so that the test samples were overturned to be left in a state in which normal pressure was reduced by 70 kPa, and after the pressure was returned to normal pressure ten minutes later, it was visually confirmed whether or not there was liquid leakage from the gaps between the fitting portions of the respective components.
  • the test samples having shapes according to those in FIGS. 1 to 6 , and in which its total height is 100 mm and the diameter of the tube section of the movable body is 22 mm were used. The results are shown in Table 2.
  • the present invention may have broad applicability as a before-use mixing container in which it is possible to perform a mixing operation for two types of medicinal solutions in its container independently of an uncovering operation for a cap or the like.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Package Specialized In Special Use (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
US13/260,496 2009-04-23 2010-04-19 Before-use mixing container Abandoned US20120024862A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009104780 2009-04-23
JP2009-104780 2009-04-23
PCT/JP2010/056937 WO2010122981A1 (fr) 2009-04-23 2010-04-19 Récipient pour mélange avant l'utilisation

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US20120024862A1 true US20120024862A1 (en) 2012-02-02

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US13/260,496 Abandoned US20120024862A1 (en) 2009-04-23 2010-04-19 Before-use mixing container

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US (1) US20120024862A1 (fr)
EP (1) EP2423124A4 (fr)
JP (1) JPWO2010122981A1 (fr)
KR (1) KR20120009424A (fr)
CN (1) CN102421683A (fr)
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KR20120009424A (ko) 2012-01-31
TW201106942A (en) 2011-03-01
WO2010122981A1 (fr) 2010-10-28
JPWO2010122981A1 (ja) 2012-10-25
EP2423124A4 (fr) 2013-05-29
CA2757355A1 (fr) 2010-10-28
CN102421683A (zh) 2012-04-18

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