US20030012685A1 - Microbicidal agents - Google Patents

Microbicidal agents Download PDF

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Publication number
US20030012685A1
US20030012685A1 US10/204,821 US20482102A US2003012685A1 US 20030012685 A1 US20030012685 A1 US 20030012685A1 US 20482102 A US20482102 A US 20482102A US 2003012685 A1 US2003012685 A1 US 2003012685A1
Authority
US
United States
Prior art keywords
opp
active compound
mit
active
phenylphenol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/204,821
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English (en)
Inventor
Peter Wachtler
Martin Kugler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lanxess Deutschland GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7632145&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US20030012685(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Assigned to BAYER AKTIENGESELLSCHAFT reassignment BAYER AKTIENGESELLSCHAFT ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KUGLER, MARTIN, WACHTLER, PETER
Publication of US20030012685A1 publication Critical patent/US20030012685A1/en
Assigned to LANXESS DEUTSCHLAND GMBH reassignment LANXESS DEUTSCHLAND GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BAYER AG
Priority to US12/469,344 priority Critical patent/US20100093815A1/en
Priority to US13/037,444 priority patent/US8246942B2/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system

Definitions

  • the present invention provides microbicidal compositions having improved bactericidal activity.
  • the invention relates to synergistic mixtures of o-phenylphenol (OPP) with other microbicidally active compounds, such as, for example, bronopol (2-bromo-2-nitro-1,3-propanediol), MIT (2-methyl-2H-isothiazol-3-one), Tektamer 38 (1 ,2-dibromo-2,4-dicyanobutane).
  • OPP o-phenylphenol
  • OPP o-Phenylphenol
  • active compound mixtures of OPP and at least one further bactericide have an unexpectedly high, synergistically enhanced activity.
  • the amounts of active compound to be employed for protecting industrial products can be reduced, resulting in more economical use or in a contribution to increased preservation quality.
  • the mixtures according to the invention are an improvement compared to the prior art, i.e. the use of the individual active compounds.
  • the novel active compound mixtures are preferably used to preserve functional liquids and water-containing industrial products susceptible to attack by microorganisms.
  • the active compound mixtures according to the invention can be used, for example, for protecting the following industrial products:
  • starch solutions, dispersions or slurries or other starch-based products such as, for example, thickeners used in printing
  • slurries of other raw materials such as color pigments (for example, iron oxide pigments, carbon black pigments, titanium dioxide pigments) or slurries of fillers such as kaolin or calcium carbonate
  • concrete additives for example those based on molasses or ligninosulfonates
  • bitumen emulsions [0009] bitumen emulsions
  • mineral oils or mineral oil products such as, for example diesel fuels
  • auxiliaries for the leather, textile or photochemical industry are auxiliaries for the leather, textile or photochemical industry.
  • Tektamer 38 (1,2-dibromo-2,4-dicyanobutane).
  • the mixing ratio of o-phenylphenol (OPP) to the other bactericidally active component can be varied within a wide range, the optimum depending, for example, on the bactericidal mixing partner used, but also on the application in question.
  • the weight ratio of o-phenylphenol (OPP) to the mixing partner should be from 99.9:0.1 to 50:50, preferably from 99:1 to 70:30, particularly preferably from 80:20 to 60:40.
  • the active compound combinations according to the invention are highly active against microorganisms.
  • the active compound combinations according to the invention are used in the protection of materials for protecting industrial materials, in particular for protecting aqueous functional liquids; they act against bacteria and molds, and also against yeast and slime organisms.
  • the following microorganisms may be mentioned by way of example, without imposing any limitations:
  • Alternaria such as Alternana tenuis, Aspergillus, such as Aspergillus niger, Chaetomium, such as Chaetomium globosum, Fusarium, such as Fusarium solani, Lentinus, such as Lentinus tigrinus, Penicillium, such as Penicillium glaucum;
  • Alcaligenes such as Alcaligenes faecalis, Bacillus, such as Bacillus subtilis, Escherichia, such as Escherichia coli, Pseudomonas, such as Pseudomonas aueruginosa or Pseudomonas fluorescens, Staphylococcus, such as Staphylococcus aureus;
  • Candida such as Candida albicans, Geotrichum, such as Geotrichum candidum;
  • the active compound combinations according to the invention can be added either separately, in the form of the individual active compounds, where it is possible, depending on the present preservation problem, to adjust the concentration ratio individually, or they can be converted into customary formulations, such as solutions, emulsions, suspensions, powders, foams, pastes, granules, aerosols or microencapsulations in polymeric substances.
  • formulations are prepared in a manner known per se, for example by mixing the active compounds with extenders, i.e. liquid solvents, liquefied gases under pressure and/or solid carriers, if appropriate with the use of surfactants, i.e. emulsifiers and/or dispersants and/or foam formers.
  • extenders i.e. liquid solvents, liquefied gases under pressure and/or solid carriers, if appropriate with the use of surfactants, i.e. emulsifiers and/or dispersants and/or foam formers.
  • surfactants i.e. emulsifiers and/or dispersants and/or foam formers.
  • the extender used is water, it is also possible to use, for example, organic solvents as auxiliary solvents.
  • suitable liquid solvents include: aromatic compounds, such as xylene, toluene, alkylnaphthalenes, chlorinated aromatic compounds or chlorinated aliphatic hydrocarbons, such as chlorobenzenes, chloroethylenes, or methylene chloride, aliphatic hydrocarbons, such as cyclohexane or paraffins, for example mineral oil fractions, alcohols, such as butanol or glycol or ethers and esters thereof, ketones, such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents, such as dimethylformamide or dimethyl sulfoxide, and also water; liquefied gaseous extenders or carriers are to be understood as meaning liquids which are gaseous at ambient temperature and under atmospheric pressure, for example aerosol propellants, such as halogenated hydrocarbons and also butane, propane, nitrogen and carbon dioxide; suitable solid carriers are: for example aero
  • Tackifiers such as carboxymethylcellulose and natural and synthetic polymers in the form of powders, granules or latices, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, and also natural phospholipids, such as cephalins and lecithins and synthetic phospholipids can be used in the formulations.
  • Other possible additives are mineral and vegetable oils.
  • microbicidal compositions or concentrates used for protecting the industrial materials comprise the active compound combination in a concentration of from 0.1 to 95% by weight, and in particular from 5 to 50% by weight.
  • the use concentrations of the active compound combinations to be used according to the invention depend on the nature and the occurrence of the microorganisms to be controlled and on the composition of the material to be protected.
  • the optimum amount for use can be determined by test series.
  • the use concentrations are in the range from 0.01 to 5% by weight, preferably from 0.05 to 2.0% by weight, based on the material to be protected.
  • the active compound combinations according to the invention show synergistic effects, i.e. the activity of the mixture is greater than the activity of the individual components.
  • Q a the amount of component A in the active compound mixture which achieves the desired effect, i.e. no microbial growth.
  • Q A the amount of component A which, when used on its own, suppresses the growth of the microorganisms.
  • Q b the amount of component B in the active compound mixture which suppresses the growth of the microorganisms.
  • Q b the amount of component B which, when used on its own, suppresses the growth of the microorganisms.
  • a synergistic index of ⁇ 1 indicates a synergistic effect for the active compound mixture.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
US10/204,821 2000-02-24 2001-02-12 Microbicidal agents Abandoned US20030012685A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/469,344 US20100093815A1 (en) 2000-02-24 2009-05-20 Microbicidal compositions
US13/037,444 US8246942B2 (en) 2000-02-24 2011-03-01 Microbicidal compositions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10008507A DE10008507A1 (de) 2000-02-24 2000-02-24 Mikrobizide Mittel
DE10008507.5 2000-02-24

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/469,344 Continuation US20100093815A1 (en) 2000-02-24 2009-05-20 Microbicidal compositions

Publications (1)

Publication Number Publication Date
US20030012685A1 true US20030012685A1 (en) 2003-01-16

Family

ID=7632145

Family Applications (3)

Application Number Title Priority Date Filing Date
US10/204,821 Abandoned US20030012685A1 (en) 2000-02-24 2001-02-12 Microbicidal agents
US12/469,344 Abandoned US20100093815A1 (en) 2000-02-24 2009-05-20 Microbicidal compositions
US13/037,444 Expired - Lifetime US8246942B2 (en) 2000-02-24 2011-03-01 Microbicidal compositions

Family Applications After (2)

Application Number Title Priority Date Filing Date
US12/469,344 Abandoned US20100093815A1 (en) 2000-02-24 2009-05-20 Microbicidal compositions
US13/037,444 Expired - Lifetime US8246942B2 (en) 2000-02-24 2011-03-01 Microbicidal compositions

Country Status (12)

Country Link
US (3) US20030012685A1 (fr)
EP (3) EP1502505B1 (fr)
JP (2) JP2003523367A (fr)
AT (3) ATE556590T1 (fr)
AU (1) AU2001240613A1 (fr)
BR (2) BR0108692B1 (fr)
DE (3) DE10008507A1 (fr)
DK (1) DK1259110T3 (fr)
ES (3) ES2240424T3 (fr)
NO (2) NO330035B1 (fr)
PT (1) PT1259110E (fr)
WO (1) WO2001062081A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080234387A1 (en) * 2005-10-13 2008-09-25 Lanxess Deutschland Gmbh Active Substance Mixtures Comprising Opp and Amines, Microbicidal Agents
US20090120327A1 (en) * 2005-01-26 2009-05-14 Matthias Buri Method for Controlling Microbial Contamination, Mineral Suspensions Obtained and Uses Thereof
EP2687092A1 (fr) * 2009-09-25 2014-01-22 Dow Global Technologies LLC Composition antimicrobienne synergique contenant d'ortho-phenylphenol et de tris(hydroxymethyl)nitromethane

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10042894A1 (de) * 2000-08-31 2002-03-14 Thor Chemie Gmbh Synergistische Biozidzusammensetzung mit 2-Methylisothiazolin-3-on
EP1502508B1 (fr) * 2002-01-31 2011-02-23 Rohm And Haas Company Associations microbicides synergiques
KR102103214B1 (ko) * 2012-05-24 2020-04-22 다우 글로벌 테크놀로지스 엘엘씨 살미생물 조성물
WO2016196116A1 (fr) * 2015-05-31 2016-12-08 Dow Global Technologies Llc Composition microbicide contenant de l'ortophénylphénol et de l'isothiazolinone

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592893A (en) * 1967-04-26 1971-07-13 Henkel & Cie Gmbh Nitro alcohols in synergistic antimicrobic compositions
US3833731A (en) * 1970-12-28 1974-09-03 Merck & Co Inc Dihalomethylglutaronitriles used as antibacterial and antifungal agents
US4800196A (en) * 1985-08-06 1989-01-24 Earth Chemical Co., Ltd. Phenyl salicylate and benzyl salicylate as acaricidal agents
US5464851A (en) * 1990-04-27 1995-11-07 Zeneca Limited Biocide composition and use
US5622546A (en) * 1993-08-20 1997-04-22 Bayer Aktiengesellschaft Mould-resistant emulsion paints
US5681852A (en) * 1993-11-12 1997-10-28 The Procter & Gamble Company Desquamation compositions
US5767137A (en) * 1994-02-08 1998-06-16 Bayer Aktiengesellschaft 1,3,2-benzodithiazol-1-oxides as microbiocides
US6217642B1 (en) * 1995-09-20 2001-04-17 Bayer Aktiengesellschaft Benzothiophene-2-carboxamide s,s-dioxides for use in anti-fouling applications
US6291549B1 (en) * 1996-10-24 2001-09-18 Bayer Aktiengesellschaft Antifouling paints

Family Cites Families (15)

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US3829305A (en) * 1971-07-06 1974-08-13 Betz Laboratories Slime control compositions containing phenolic compounds and their use
GB1505069A (en) * 1974-06-07 1978-03-22 Exxon Research Engineering Co Oil-in-water emulsions with bacteriaresistance
US4939266A (en) 1982-06-01 1990-07-03 Rohm And Haas Company Nitrosamine-free 3-isothiazolone
CA1189514A (fr) * 1982-06-01 1985-06-25 Horst O. Bayer 3-isothiazolones exempts de nitrosamine et methode de preparation
GB8334422D0 (en) * 1983-12-23 1984-02-01 Sterwin Ag Composition
JPH03130758A (ja) * 1989-10-16 1991-06-04 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
ATE106183T1 (de) * 1990-04-27 1994-06-15 Zeneca Ltd Biozide zusammensetzung und ihre verwendung.
JPH0683720B2 (ja) * 1990-06-19 1994-10-26 日本曹達株式会社 循環式トイレ処理剤
IT1247918B (it) * 1991-05-10 1995-01-05 Germo Spa Composizioni disinfettanti polivalenti
JPH08253404A (ja) * 1995-03-17 1996-10-01 Katayama Chem Works Co Ltd 工業用殺菌組成物
US5641808A (en) * 1995-09-01 1997-06-24 Calgon Corporation Synergistic antimicrobial composition of 1,2-dibromo-2,4-dicyanobutane and esters of parahydroxybenzoic acid
JP3855569B2 (ja) * 1998-12-04 2006-12-13 コニカミノルタホールディングス株式会社 インクジェット用インク
AU6898500A (en) * 1999-08-09 2001-03-05 David A. Kist Tape stripping system and method
US7354423B2 (en) 1999-08-09 2008-04-08 J&J Consumer Co., Inc. Skin abrasion system and method
GB2354771A (en) 1999-10-01 2001-04-04 Mcbride Ltd Robert Bactericide combinations in detergents

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592893A (en) * 1967-04-26 1971-07-13 Henkel & Cie Gmbh Nitro alcohols in synergistic antimicrobic compositions
US3833731A (en) * 1970-12-28 1974-09-03 Merck & Co Inc Dihalomethylglutaronitriles used as antibacterial and antifungal agents
US4800196A (en) * 1985-08-06 1989-01-24 Earth Chemical Co., Ltd. Phenyl salicylate and benzyl salicylate as acaricidal agents
US5464851A (en) * 1990-04-27 1995-11-07 Zeneca Limited Biocide composition and use
US5622546A (en) * 1993-08-20 1997-04-22 Bayer Aktiengesellschaft Mould-resistant emulsion paints
US5681852A (en) * 1993-11-12 1997-10-28 The Procter & Gamble Company Desquamation compositions
US5767137A (en) * 1994-02-08 1998-06-16 Bayer Aktiengesellschaft 1,3,2-benzodithiazol-1-oxides as microbiocides
US6217642B1 (en) * 1995-09-20 2001-04-17 Bayer Aktiengesellschaft Benzothiophene-2-carboxamide s,s-dioxides for use in anti-fouling applications
US6291549B1 (en) * 1996-10-24 2001-09-18 Bayer Aktiengesellschaft Antifouling paints

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090120327A1 (en) * 2005-01-26 2009-05-14 Matthias Buri Method for Controlling Microbial Contamination, Mineral Suspensions Obtained and Uses Thereof
US8877127B2 (en) 2005-01-26 2014-11-04 Omya International Ag Process for control of microbial contamination, mineral suspensions obtained and their uses
US8889068B2 (en) * 2005-01-26 2014-11-18 Omya International Ag Method for controlling microbial contamination, mineral suspensions obtained and uses thereof
TWI465265B (zh) * 2005-01-26 2014-12-21 Omya Int Ag 用於控制微生物污染的方法，所得的無機物懸浮液及其用途
US20080234387A1 (en) * 2005-10-13 2008-09-25 Lanxess Deutschland Gmbh Active Substance Mixtures Comprising Opp and Amines, Microbicidal Agents
US9119395B2 (en) 2005-10-13 2015-09-01 Lanxess Deutschland Gmbh Active substance mixtures comprising OPP and amines, microbicidal agents
EP2687092A1 (fr) * 2009-09-25 2014-01-22 Dow Global Technologies LLC Composition antimicrobienne synergique contenant d'ortho-phenylphenol et de tris(hydroxymethyl)nitromethane
CN103518716A (zh) * 2009-09-25 2014-01-22 陶氏环球技术有限公司 协同抗微生物组合物
CN103518716B (zh) * 2009-09-25 2015-05-27 陶氏环球技术有限公司 协同抗微生物组合物

Also Published As

Publication number Publication date
ES2384169T3 (es) 2012-07-02
ES2240424T3 (es) 2005-10-16
BR0108692A (pt) 2002-12-10
EP1502505A2 (fr) 2005-02-02
DE10008507A1 (de) 2001-08-30
DE50106035D1 (de) 2005-06-02
BR122012016624B1 (pt) 2015-04-14
ATE556590T1 (de) 2012-05-15
WO2001062081A2 (fr) 2001-08-30
JP2003523367A (ja) 2003-08-05
EP1502505B1 (fr) 2006-08-23
DE50110837D1 (de) 2006-10-05
ATE293884T1 (de) 2005-05-15
EP1259110B1 (fr) 2005-04-27
BR0108692B1 (pt) 2013-02-05
PT1259110E (pt) 2005-08-31
EP1502506A3 (fr) 2005-02-16
WO2001062081A3 (fr) 2002-06-20
EP1502506B1 (fr) 2012-05-09
US20100093815A1 (en) 2010-04-15
EP1502505A3 (fr) 2005-02-16
NO20023972L (no) 2002-08-21
ATE336894T1 (de) 2006-09-15
ES2271760T3 (es) 2007-04-16
DK1259110T3 (da) 2005-08-01
EP1502506A2 (fr) 2005-02-02
US8246942B2 (en) 2012-08-21
NO333350B1 (no) 2013-05-13
NO20023972D0 (no) 2002-08-21
JP2011251993A (ja) 2011-12-15
NO20110006L (no) 2002-08-21
NO330035B1 (no) 2011-02-07
AU2001240613A1 (en) 2001-09-03
EP1259110A2 (fr) 2002-11-27
US20120035228A1 (en) 2012-02-09

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Legal Events

Date Code Title Description
AS Assignment

Owner name: BAYER AKTIENGESELLSCHAFT, GERMANY

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:WACHTLER, PETER;KUGLER, MARTIN;REEL/FRAME:013374/0425;SIGNING DATES FROM 20020716 TO 20020717

AS Assignment

Owner name: LANXESS DEUTSCHLAND GMBH, GERMANY

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BAYER AG;REEL/FRAME:018584/0319

Effective date: 20061122

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION