US20010049546A1 - Multi-purpose drug and heat therapy treatment system - Google Patents
Multi-purpose drug and heat therapy treatment system Download PDFInfo
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- US20010049546A1 US20010049546A1 US09/756,059 US75605901A US2001049546A1 US 20010049546 A1 US20010049546 A1 US 20010049546A1 US 75605901 A US75605901 A US 75605901A US 2001049546 A1 US2001049546 A1 US 2001049546A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0001—Body part
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0225—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0261—Compresses or poultices for effecting heating or cooling medicated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
- A61F7/032—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction using oxygen from the air, e.g. pocket-stoves
- A61F7/034—Flameless
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Definitions
- warts One of the prime examples of a medical condition that has recently been found to be treatable with heat therapy is warts.
- the present invention is not limited to warts, the efficacy of using heat for wart treatment is detailed herein as an example of the benefit of the present invention.
- Warts are very common viral induced growths (infectious process) and have long presented problems to individuals due to the pain, discomfort and the cosmetic problems associated therewith.
- various methods and treatments have been developed over the years for reducing or eliminating the undesirable effects associated with warts, these prior art applications, treatments and methods have been incapable of eliminating or curing warts or the problems associated with them.
- the skin is divided into three layers, the epidermis, the dermis, and the subcutaneous tissue.
- the outer layer of the skin is called the epidermis, and varies in thickness from about 0.3 mm on the eyelids and flexural areas to 1.55 mm on the palms and soles.
- the outermost layer of the epidermis is the stratum corneum (horny layer), which is comprised of completely keratinized dead cells. The thickness of the stratum corneum varies greatly on different parts of the body, being thickest on the palms and soles and totally absent on the oral mucosa.
- the bottommost layer of the epidermis rests upon the basement membrane separating the epidermis from the dermis.
- the basel cells are the epidermal cells that proliferate.
- the basal cells proliferate and, by cell division, form the keratinocytes (squamous cell layer, stratum spinosum, spinous layer).
- the keratinocytes synthesize insoluble protein which remains in the cells and will eventually become a major component of the outer layer (the stratum corneum, horny layer).
- the keratinocytes continue to divide and to migrate from the bottommost layer to the outermost layer, until the cells finally die. In this process of keratinization, the cells continue to flatten and their cytoplasm appears granular (stratum granulosum, granular layer) until they finally die as they reach the surface to form the stratum corneum (horny layer).
- Warts are known to be intra-epidermal tumors of the skin caused by infection with the human papilloma virus (HPV).
- HPV human papilloma virus
- the HPV induces an abnormal increase of cells in the skin tissue, commonly referred to as hyperplasia, with the hyperplasia being limited to the squamous epithelium.
- replication of the papilloma virus is confined to the nuclei of the upper layer of infected epidermal cells.
- warts Many different methods and application systems have been developed to treat warts. However, none of them are uniformly effective. The most common treatments for eliminating warts are surgery, such as conventional surgery, laser surgery, and cryosurgery, the application of different acidic or caustic chemicals in order to completely remove the affected area, and other topical substances, and immune response modifier, such as Interferon imiquimod, DNCB etc.
- these processes are as difficult or as uncomfortable as the wart condition itself.
- the warts may return, and patients may be left with pain and/or scar formation. Consequently, many individuals avoid these treatments and, instead, merely accept the discomfort associated with their warts. Unfortunately, when warts are left alone, they may also spread, as a viral infectious process.
- hot water baths are extremely difficult to employ since the entire body part, not only the wart, must be immersed into the hot water. This is particularly difficult since long time exposures are required, as well as repeated exposures several times a day. Furthermore, the hot water bath procedure is particularly hazardous to children due to the risk of severe burning.
- warts exemplify the numerous conditions that can be effectively treated if a dependable delivery system for providing heat therapy were available. Similarly, these numerous other medical problems are also effectively treated using a similar dependable delivery system which provides controlled heat therapy.
- Another object of the present invention is to provide a treatment system having the characteristic features described above which is capable of providing a constant level of heat for extended periods of time by controlling air flow and heat insulation.
- Another object of the present invention is to provide a treatment system having the characteristic features described above which is easily used by a consumer and enables the treatment system to be retained in any desired position or location for any desired length of time.
- a further object of the present invention is to provide a treatment system having the characteristic features described above which is capable of being constructed to be easily reused.
- Another object of the present invention is to provide a treatment system having the characteristic features described above which is capable of being constructed as a single-use system which is easily applied to the skin surface for attaining the desired heat benefits and then disposed after use.
- Another object of the present invention is to provide a treatment system having the characteristic features described above which is capable of providing consistent, repeatable, reproducible, and reliable temperature levels in a convenient, easily attained, safe manner.
- a treatment system which comprises, at a minimum, a fully integrated, easily employed holding or support member which is uniquely constructed for cooperating with a heat delivery patch or exothermic pad for optimizing the application of heat directly to a precisely desired location.
- an extremely novel, fully integrated treatment system which possesses broad applicability for a wide range of medical conditions.
- medical conditions such as psoriasis, skin cancers, warts, leishmaniasis, mycobacteria, and granuloma annulare can be treated or improved by heat penetration into the skin, subcutaneous tissues, joints, muscles, blood streams, etc.
- the application of heat has been found to slow, inhibit, or reverse metabolic processes, immunological processes, or biological conditions or processes which depend upon heat or are affected by heat.
- numerous medical conditions are effectively treated by employing the integrated treatment system of the present invention.
- Exothermic pads or heat delivery patches have been previously developed and typically comprise a porous film or pad of woven or non-woven material incorporating chemicals which will react exothermically to generate heat in the presence of oxygen.
- exothermic pads or heat delivery patches typically contain moxa or a mixture of iron powder, activated charcoal, wood fibers, water and salt.
- a mixture of alkaline sulfides and iron carbide are employed with the chemicals stored in an inert, oxygen-free, chamber to prevent exposure to oxygen prior to use.
- the pores of the pad are of sufficient size to assure that the required air flow is achieved.
- the patch/pad Prior to use, the patch/pad is typically sealed within a pouch with an inert gas, such as nitrogen. As long as the patch/pad remains in the sealed container until use, no chemical reaction takes place. However, once the pouch is open, the presence of the oxygen in the air causes the chemicals to react and the desired exothermic reaction is produced.
- an inert gas such as nitrogen
- the exothermic pad or heat delivery patch is separately employed by having the user place the pad or patch on the desired site where heat treatment is being sought.
- the heat delivery patch or exothermic pad is separately secured to the desired site by adhesive means associated therewith.
- any desired securement method may be employed.
- the support or holding member of the treatment system of the present invention is affixed to the desired location, peripherally surrounding and securely maintaining the heating pad or exothermic patch in the desired location, assisting in regulating and controlling the heat level and air transmission to the exothermic pad or heat delivery patch.
- the desired, controlled heat delivery or heat gradient is realized, enabling a broad range of medical conditions to be effectively treated.
- the use of a heat gradient as provided by the fully integrated treatment system of the present invention is effective, improving and enhancing the penetration of systemic and topical medications such as corticosteroids, chemotherapeutic agents, anesthetics, antihistamines, anti-infectives, anti-bacterials, anti-parasitics, anti-viral agents, anti-oxidants, immunomodulators, keratolytics, and anti-neoplastics.
- systemic and topical medications such as corticosteroids, chemotherapeutic agents, anesthetics, antihistamines, anti-infectives, anti-bacterials, anti-parasitics, anti-viral agents, anti-oxidants, immunomodulators, keratolytics, and anti-neoplastics.
- systemic and topical medications such as corticosteroids, chemotherapeutic agents, anesthetics, antihistamines, anti-infectives, anti-bacterials, anti-parasitics, anti-viral agents,
- corticosteroids may comprise one or more selected from the group consisting of hydrocortisone, triamcinolone, betamethasone, and any other steroids commonly used in topical applications to the skin;
- chemotherapeutic agents may comprise one or more selected from the group consisting of 5FU, Bleomycin, cytotoxic agents;
- anesthetics may comprise one or more selected from the group consisting of lidocaine, prilocaine, and pramoxine;
- antihistamines may comprise one or more selected from the group consisting of diphenhydramine and its salts;
- anti-infectives, such as anti-fungals may comprise one or more selected from the group consisting of clotrimazole and ciclopirox;
- anti-bacterials may comprise one or more selected from the group consisting of gentamicin, tetracycline, erythromycin, and clindamycin;
- anti-parasitics may comprise one or more selected from the group consisting of metronidazole, permethrin
- skin penetration enhancing agents which benefit from the use of the present invention comprise one or more selected from the group consisting of solvents, surfactants, ethers, esters, fatty acid glycerides, urea, oleates, liposomes, retinoids, and occlusive compounds.
- this treatment system incorporates a heat delivery patch or exothermic pad in combination with a holding member which maintains the heat delivery patch or exothermic pad in a precisely desired location where the particular medical problem is manifested or where heat delivery or a heat gradient is desired.
- skin penetration enhancing agents and/or cosmetics may be integrated into the treatment system of this invention for further enhancement of its efficacy.
- the wart virus is inactivated or slowed in its development, thereby preventing further invasion of the virus to adjacent tissue.
- the normal reparative process of the skin takes effect, moving in the infected portion to a higher and higher level into the spinous layer of the epidermis, towards the surface of the skin, until the wart is shed in the normal process with the stratum corneum.
- the temperature of the skin is elevated and maintained between about 39° to 44° C., for periods of time ranging between about 1 and 10 hours.
- the heat level to which the skin is exposed is maintained in a small, controlled range, which represents the optimum heat exposure for killing and inactivating the wart virus. As a result, optimum performance and treatment is realized.
- keratolytic chemical agents may be incorporated with and/or into the exothermic pad to assist in reducing the thickness of the epidermis, particularly the stratum corneum.
- stratum corneum any removal of the outermost horny layer technically eliminates a portion of the wart as well as the viral particles contained therein, destroying the viral particles by shedding.
- the thinning of the stratum corneum enables the heat to penetrate deeper within the wart lesion, thereby achieving greater efficacy from the application of the pad.
- keratolytic agents can be incorporated with and/or into the exothermic pad in order to reduce the upper layer of the epidermis, it has been found that salicylic acid or salicylic and lactic acid are preferable, since such chemicals may be incorporated with and/or into the exothermic pad to attain the desired beneficial results.
- the exothermic pad may operate more effectively, since the thickness of the epidermis is reduced, thereby allowing the heat generated by the exothermic pad to penetrate the wart to a greater extent.
- immune response modifiers such as interferon, imiquimod, DNCB, etc. may also be employed with equal efficacy.
- the support member is specifically designed for being quickly and easily mountable to any location on an individual where a wart is normally found and remain in the precisely desired location in cooperating association with the heat delivery patch or exothermic pad.
- the support member cooperates with the heat delivery patch or exothermic pad to securely maintain the patch/pad in direct association with the wart.
- the support member of the present invention is also specifically constructed from material particularly designed for cooperating with a heat delivery patch or exothermic pad to synergistically interact therewith for assuring that the precisely required temperature levels are maintained and optimum oxygen flow is realized for the precisely desired period of time.
- the support member forming the holding system of the present invention may be constructed in a variety of alternate configurations for providing the desired, quicky, easy, secure mounting thereof directly to any portion of the human anatomy where wart treatment is likely to be needed.
- warts are most typically found on the extremities, thereby enabling the holding system of the present invention to comprise a construction which is quickly and easily mounted to an individual's hands, feet, toes, fingers, arms, forearms, legs, thighs, elbows, knees, head, and torso.
- one preferred embodiment of the holding system of the present invention comprises a continuous, substantially cylindrically shaped tube member.
- the holding system of the present invention is able to be easily mounted onto the hands, feet, arms, legs, etc. of the user, peripherally surrounding the hands, feet, arms or legs, and securely maintaining and cooperating with the pre-mounted exothermic pad or heat delivery patch in the precisely desired location.
- a cylindrically shaped holding system is preferred for most applications, alternate constructions can also be employed. Such alternate constructions include cones, truncated cones, closed-end cylinders, and elongated strips of various sizes incorporating fastening means, such as snaps, velcro, adhesives, etc. mounted at opposed ends for securing the holding system in peripheral surrounding engagement with any desired area of the human anatomy.
- fastening means such as snaps, velcro, adhesives, etc. mounted at opposed ends for securing the holding system in peripheral surrounding engagement with any desired area of the human anatomy.
- tightening means preferably in the form of an elongated strip member mounted on the outside surface of the cylindrical holding system, can be employed in order to assure secure, snug, mounted engagement of the treatment system in the precisely desired location.
- One principal feature of the present invention is the material employed for forming the treatment system of this invention.
- most woven or non-woven materials are capable of being employed for forming the holding member.
- the preferred material comprises an elastomer with its entirety or formed therein, in order to provide flexibility in easily mounting and securing the holding system in place.
- the elastomer is integrally formed as a part of the material, such as a thermoplastic elastomer.
- the preferred thermoplastic material comprises a foamed thermoplastic elastomer selected from the group consisting of polyurethane, polyolefins, polybutylenes, polyethylenes, polyesters, ethylenepropylene rubbers, polypropylenes, silicones, and vinyl based resins.
- the temperature delivered directly to the wart by the exothermic pad or heat delivery patch is precisely controlled in a narrow range, for a determined length of time, due to the insulation provided by the holding system.
- oxygen is circulated continuously through the holding system to provide proper operation of the exothermic pad/patch as well as provide air circulation to the surface of the skin being treated.
- the invention accordingly comprises an article of manufacture possessing the features, properties, physical characteristics, qualities of the material being employed, and relation of elements which will be exemplified in the article hereinafter described and the scope of the invention will be indicated in the claims.
- FIG. 1 is a perspective view of one embodiment of the treatment system of the present invention with the holding member thereof mounted to a hand with an exothermic patch mounted to a finger of the hand;
- FIG. 2 is a perspective view of the holding member of FIG. 1;
- FIG. 3 is a perspective view of an alternate construction of the holding member of the treatment system of the present invention.
- FIG. 4 is a perspective view of a further alternate embodiment of the holding member of the treatment system of the present invention.
- FIG. 5 is a perspective view of a still further alternate embodiment of the holding member of the treatment system of the present invention.
- FIGS. 1 - 5 depict alternate preferred constructions for the treatment system of the present invention.
- the embodiments are disclosed for exemplary purposes only, and are not intended as a limitation of the present invention. Consequently, alternate constructions and configurations for the system of the present invention can be made and are intended to be within this scope of the present invention.
- treatment system 20 comprises a multi-component, fully integrated, easily employed construction for providing optimum delivery of heat therapy and/or a heat gradient to any desired location on the human anatomy for imparting medical benefits for a wide variety of various disorders and conditions.
- treatment system 20 comprises holding member 21 and exothermic pad or heat delivery patch 28 .
- any desired drugs, skin penetration enhancing agents and/or cosmetics may also be combined as part of treatment system 20 in order to attain desired enhanced medicinal benefits.
- the present invention achieves an extremely novel, fully integrated treatment system having broad applicability for a wide range of medical conditions.
- the application of heat has been found to slow, inhibit, or reverse metabolic processes, immunological processes, or biological conditions or processes, which depend upon heat or are affected by heat.
- broad applicability and extensive benefits are achieved by the present invention.
- FIGS. 2 - 3 alternate, exemplary embodiments of holding member 21 of treatment system 20 are depicted.
- one embodiment of treatment system 20 of the present invention is depicted as comprising a hollow, continuous, cylindrically shaped holding member 21 having an outer surface 22 and an inner surface 24 .
- holding member 21 may comprise any desired alternate size, shape, or configuration, and discussed herein.
- treatment system 20 of the present invention in a manner which will provide controlled heating of any desired site where treatment is being sought, reference should be made to FIG. 1.
- FIG. 1 the existence of a wart on finger 25 of hand 26 is depicted for exemplary purposes, with exothermic pad or heat delivery patch 28 mounted to finger 25 in overlying engagement with the wart formed thereon.
- treatment system 20 of the present invention is placed about the fingers of hand 26 , in overlying, secure, co-operative engagement with exothermic pad 28 .
- holding system 20 By securely mounting holding system 20 in overlying, cooperative engagement with heat delivery patch or exothermic pad 28 , holding system 20 provides the desired co-operative association with pad/patch 28 to assure controlled heat delivery and oxygen circulation directly to the desired location. In this way, protection of the desired site is provided, along with control of the temperature to which the skin surface is exposed. As a result, the precisely desired temperature is delivered to the wart, within a desired, narrow range and for the precise length of time needed for killing the wart virus.
- treatment system 20 of the present invention is also capable of treating other medical conditions such as psoriasis, skin cancers, leishmaniasis, mycobacteria, and granuloma annulare.
- Each of these conditions can be treated or improved by heat penetration into the skin, subcutaneous tissues, joints, muscles, blood streams, etc.
- the application of heat has been found to slow, inhibit, or reverse metabolic processes, immunological processes, or biological conditions or processes which depend upon heat or are affected by heat.
- numerous medical conditions are effectively treated by employing the integrated treatment system of the present invention.
- corticosteroids may comprise one or more selected from the group consisting of hydrocortisone, triamcinolone, and betamethasone and any other steroid commonly used in topical applications to the skin;
- chemotherapeutic agents may comprise one or more selected from the group consisting of 5FU, Bleomycin, cytotoxic agents;
- anesthetics may comprise one or more selected from the group consisting of lidocaine, prilocaine and pramoxine;
- antihistamines may comprise one or more selected from the group consisting of diphenhydramine and its salts;
- anti-infectives, such as anti-fungals may comprise one or more selected from the group consisting of clotrimazole and ciclopirox;
- anti-bacterials may comprise one or more selected from the group consisting of gentamicin, tetracycline, erythromycin, and clindamycin;
- anti-parasitics may comprise one or more selected from the group consisting of metronidazole, permethr
- skin penetration enhancing agents which benefit from the use of the present invention comprise one or more selected from the group consisting of solvents, surfactants, ethers, esters, fatty acid glycerides, urea, oleates, liposomes, retinoids, and occlusive compounds.
- solvents may comprise one or more selected from the group consisting of dimethyl sulfoxide, dimethyl acetamide, dimethyl formamide, diethyl-m-toluamide, and n-methyl pyrrolidone; alcohols may comprise one or more selected from the group consisting of ethanol and isopropanol; glycols may comprise one or more selected from the group consisting of propylene glycol, polyethylene glycols, and glycerin; ketones may comprise one or more selected from the group consisting of acetone; surfactants, including anionic surfactants, may comprise one or more selected from the group consisting of sodium lauryl sulfate; surfactants, including non-ionic surfactants, may comprise one or more selected from the group consist
- the present invention provides a treatment system for a wide variety of medical problems and conditions.
- controlled delivery of heat therapy and/or a heat gradient is provided to any desired location on the human anatomy for imparting medical benefits for a wide variety of various disorders and conditions.
- both medicinal benefits and drug delivery are substantially enhanced.
- the treatment system of the present invention comprises holding member 21 and exothermic pad or heat delivery patch 28 , along with any desired drug, skin penetration enhancing agent and/or cosmetic which may be desired for combination therewith, as a part of treatment system 20 .
- holding member 21 may be formed in virtually any desired size or configuration.
- FIGS. 1 - 5 depict preferred alternate configurations for holding member 21 of treatment system 20 .
- holding member 21 is depicted in FIGS. 1 and 2 as a hollow, continuous, cylindrically shaped member which is easily mountable to virtually any desired location on an extremity of an individual.
- holding member 21 By constructing holding member 21 from various flexible materials, an easy mounted construction is achieved, providing the precisely desired heat therapy and/or heat gradient in virtually any desired location. In this regard, it has been found that woven or nonwoven materials can be employed for forming holding member 21 . In addition, holding member 21 may be constructed with elastomeric materials in order to provide further enhanced flexibility and mounting and securing ease.
- holding member 21 is formed from thermoplastic elastomeric materials selected from the group consisting of polyurethanes, polyolefins, polybutylenes, polyethylenes, polyesters, ethylene-propylene rubbers, polypropylenes, silicones, and vinyl-based resins. Furthermore, by constructing holding member 21 from a foamed thermoplastic elastomer, any desired combination of closed cells and open cells is obtainable, with any desired ratio being provided. In this way, heat retention and/or insulation capabilities are achieved as an integral, inherent physical characteristic of holding member 21 . In addition, by employing this construction, holding member 21 is able to transmit oxygen from the surrounding, ambient air directly to the location where the heat delivery patch or exothermic pad 28 is mounted.
- FIG. 1 depicts holding member 21 mounted about the hand of a user, peripherally surrounding all four fingers, with exothermic pad or heat delivery patch 28 mounted to finger 25 in aligned, overlying relationship with the area to be treated.
- holding member 21 may comprise forwardly projecting portion 30 which extends forward of the fingertips of the user in order to allow the fingertips to be wrapped and enclosed, if desired.
- rearwardly extending portion 31 is also depicted in FIG. 1 for showing an elongated construction incorporating a thumb finger hole 32 formed therein for ease of application and mounting to the hand of an individual.
- cylindrically shaped holding member 21 is depicted incorporating an optional securing strap 35 mounted to outer surface 22 thereof.
- securing strap 35 may incorporate a wide variety of alternate constructions, in the preferred embodiment, strap 35 comprises a continuous, elongated member having opposed ends 36 and 37 , with end 36 integrally bonded to outer surface 22 of holding member 21 .
- opposed end 37 of strap 35 is constructed for being securable to surface 22 in a wide variety of alternate locations.
- fastening means are preferably formed adjacent end 37 of strap 35 , positioned for cooperative interengagement with surface 22 of holding member 21 .
- any desired fastening means may be employed, such as adhesives, hook/loop fasteners, and the like.
- strap 35 provides the desired securement of holding member 21 in the precisely desired location.
- holding member 21 is mounted about the desired area to which the heat therapy or heat gradient is to be delivered and end 37 of strap 35 is removed from its initial engagement with surface 22 and moved into an alternate engaged location engage with surface 22 which provides the desired secure positioning of holding member 21 in the precisely desired location.
- FIG. 3 an alternate embodiment of holding member 21 of treatment system 20 of the present invention is depicted.
- an elongated, substantially continuous sheet of material is employed which is easily wrapped about any desired location for peripherally surrounding an exothermic pad or heat delivery patch 28 mounted to the desired site.
- fastening means 40 are formed on outer surface 22 of holding member 21 , with cooperating fastening means 41 formed on inner surface 24 of holding member 21 .
- fastening means 40 and 41 are depicted as hook and loop fasteners, any alternate fastening means may be employed with equal efficacy.
- holding member 21 may be constructed in any desired size and shape for enabling holding member 21 to be mounted to virtually any locations on the human anatomy.
- treatment system 20 of the present invention can be effectively employed wherever needed for providing the desired heat therapy or heat gradient, as well as the enhanced delivery of any medicines, skin penetration enhancing agents, and/or cosmetics.
- holding member 21 of treatment system 20 of the present invention is depicted.
- holding member 21 is constructed in a substantially continuous, hollow, truncated conical shaped.
- this embodiment of holding member 21 may be constructed with securing strap 35 mounted to outer surface 22 thereof, as detailed above.
- this embodiment of holding member 21 may also be constructed with an elongated slit formed in the outer surface thereof, as depicted in FIG. 3, while also incorporating fastening means 40 and 41 formed on the surfaces thereof for enabling secure wrapped interengagement of holding member 21 to any desired location.
- FIG. 5 an alternate embodiment of holding member 21 of treatment system 20 of he present invention is depicted.
- an elongated, substantially continuous sheet of material is employed which is quickly and easily affixed to any desired surface location on an individual for securely maintaining an exothermic paid or heat delivery patch 28 on the desired site.
- adhesive means 45 are formed on inner surface 24 of holding member 21 , along at least two opposed edges. If desired, adhesive means 45 may be formed about the entire peripheral edge of surface 24 to assure secure affixation of holding member 21 to any surface of the body, without requiring peripheral surrounding of the body part.
- fastening means 40 and 41 are depicted as hook and loop fasteners, any alternate fastening means may be employed with equal efficacy.
- holding member 21 may be constructed in any desired size and shape for enabling holding member 21 to be mounted to virtually any location on the human anatomy.
- treatment system 20 of the present invention can be effectively employed whenever needed for providing the desired heat therapy or heat gradient, as well as the enhanced delivery of any medicines, skin penetration enhancing agents, and/or cosmetics.
- holding member 21 of treatment system 20 of the present invention may be configured in a wide variety of alternate constructions without departing from the scope of the present invention.
- holding member 21 peripherally surrounds a pre-positioned exothermic pad or heat delivery patch 28 which has been mounted to the particular site where medicinal benefits are desired.
- by also placing drugs, skin penetration enhancing agents and/or cosmetics on the site being treated further enhanced medicinal benefits may be achieved with treatment system 20 of this invention.
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- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Control Of Heat Treatment Processes (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/756,059 US20010049546A1 (en) | 2000-02-08 | 2001-01-08 | Multi-purpose drug and heat therapy treatment system |
DE60112248T DE60112248T2 (de) | 2000-02-08 | 2001-02-02 | Allzweck -medikament und -wärmebehandlungssystem |
EP01908795A EP1255519B1 (fr) | 2000-02-08 | 2001-02-02 | Medicament et systeme de thermotherapie polyvalent |
ES01908795T ES2247064T3 (es) | 2000-02-08 | 2001-02-02 | Farmaco de multiples aplicaciones y sistema de tratamiento de terapia por calor. |
CA002398543A CA2398543A1 (fr) | 2000-02-08 | 2001-02-02 | Medicament polyvalent et systeme de thermotherapie |
AU36627/01A AU778280B2 (en) | 2000-02-08 | 2001-02-02 | Multi-purpose drug and heat therapy treatment system |
PCT/US2001/003432 WO2001058408A2 (fr) | 2000-02-08 | 2001-02-02 | Medicament polyvalent et systeme de thermotherapie |
AT01908795T ATE300262T1 (de) | 2000-02-08 | 2001-02-02 | Allzweck -medikament und -wärmebehandlungssystem |
US10/612,102 US20040097864A1 (en) | 2000-02-08 | 2003-07-01 | Multi-purpose drug and heat therapy treatment system |
US11/087,492 US20050208115A1 (en) | 2000-02-08 | 2005-03-22 | Multi-purpose combined drug delivery and heat therapy treatment system |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18104800P | 2000-02-08 | 2000-02-08 | |
US09/756,059 US20010049546A1 (en) | 2000-02-08 | 2001-01-08 | Multi-purpose drug and heat therapy treatment system |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/612,102 Continuation US20040097864A1 (en) | 2000-02-08 | 2003-07-01 | Multi-purpose drug and heat therapy treatment system |
Publications (1)
Publication Number | Publication Date |
---|---|
US20010049546A1 true US20010049546A1 (en) | 2001-12-06 |
Family
ID=26876845
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/756,059 Abandoned US20010049546A1 (en) | 2000-02-08 | 2001-01-08 | Multi-purpose drug and heat therapy treatment system |
US10/612,102 Abandoned US20040097864A1 (en) | 2000-02-08 | 2003-07-01 | Multi-purpose drug and heat therapy treatment system |
US11/087,492 Abandoned US20050208115A1 (en) | 2000-02-08 | 2005-03-22 | Multi-purpose combined drug delivery and heat therapy treatment system |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/612,102 Abandoned US20040097864A1 (en) | 2000-02-08 | 2003-07-01 | Multi-purpose drug and heat therapy treatment system |
US11/087,492 Abandoned US20050208115A1 (en) | 2000-02-08 | 2005-03-22 | Multi-purpose combined drug delivery and heat therapy treatment system |
Country Status (8)
Country | Link |
---|---|
US (3) | US20010049546A1 (fr) |
EP (1) | EP1255519B1 (fr) |
AT (1) | ATE300262T1 (fr) |
AU (1) | AU778280B2 (fr) |
CA (1) | CA2398543A1 (fr) |
DE (1) | DE60112248T2 (fr) |
ES (1) | ES2247064T3 (fr) |
WO (1) | WO2001058408A2 (fr) |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060276863A1 (en) * | 2003-05-09 | 2006-12-07 | Kao Corporation | Warming tool |
US20070123960A1 (en) * | 2001-09-17 | 2007-05-31 | Rousmaniere Sharon O | Product and method for reduction of skin itch discomfort, and disease |
US20090287280A1 (en) * | 2008-05-15 | 2009-11-19 | Wyeth | Portable moist heat system |
US20100191314A1 (en) * | 2009-01-23 | 2010-07-29 | Young Daniel L | Temperature controlled facial mask with area-specific treatments |
US20110040235A1 (en) * | 2009-08-11 | 2011-02-17 | Castel J Chris | Multi-Modal Drug Delivery System |
US20120191022A1 (en) * | 2010-07-23 | 2012-07-26 | Muehlbauer Thomas G | Methods and apparatus for therapeutic application of thermal energy |
US20130006337A1 (en) * | 2010-02-04 | 2013-01-03 | Americo Fernandes | Chemical warming device and method for the treatment of viruses such as herpes |
US9192509B2 (en) | 2013-03-11 | 2015-11-24 | Avacen, Inc. | Methods and apparatus for therapeutic application of thermal energy including blood viscosity adjustment |
US20160242958A1 (en) * | 2015-02-20 | 2016-08-25 | Jamie Flora | Thermotherapy devices for the ear |
US9687385B2 (en) | 2013-03-11 | 2017-06-27 | Avacen, Inc. | Methods and apparatus for therapeutic application of thermal energy including blood viscosity adjustment |
US9730832B2 (en) | 2009-07-26 | 2017-08-15 | Forever Young International, Inc. | Self-heated consumer spa products and applications thereof |
US20180014969A1 (en) * | 2016-07-15 | 2018-01-18 | Raymond K. Wurapa | Assistive device for remediating inflammation, swelling and pain |
US20180168855A1 (en) * | 2016-12-15 | 2018-06-21 | Penguin Fingers, Llc | Joint compress cold pack |
US11684282B2 (en) | 2017-02-03 | 2023-06-27 | Avacen, Inc. | Systems and methods for evaluating blood circulation and early detection of cardiovascular issues |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1839705A1 (fr) | 2006-03-27 | 2007-10-03 | Universidad de Alcala | Emplâtre cutané de thérapie laser |
KR101962658B1 (ko) | 2010-11-04 | 2019-07-31 | 442 벤쳐스 엘엘씨 | 피부 상태를 치료하기 위한 조성물 및 방법 |
EP3381419A1 (fr) | 2017-03-30 | 2018-10-03 | Trimb Healthcare AB | Dispositif pour une thérapie thermique de troubles cutanés |
KR101953156B1 (ko) * | 2018-11-15 | 2019-02-28 | 임하리 | 홍채를 이용한 건강 관리 방법 및 시스템 |
CN109453460A (zh) * | 2018-12-18 | 2019-03-12 | 河北鹊神生物科技有限公司 | 药石热敷灸基质、含有其的中药组合物及制备方法 |
WO2023072861A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
WO2024084038A1 (fr) * | 2022-10-20 | 2024-04-25 | Ellennbe Gmbh | Technologie de plateforme pour le traitement de maladies inflammatoires, immunologiques et/ou auto-immunologiques |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4230105A (en) * | 1978-11-13 | 1980-10-28 | Merck & Co., Inc. | Transdermal delivery of drugs |
CA1149252A (fr) * | 1980-04-09 | 1983-07-05 | Anthony J. Last | Bandage absorbeur de vibrations pour l'avant-bras |
JPH01122037U (fr) * | 1988-02-12 | 1989-08-18 | ||
US5986163A (en) * | 1992-06-19 | 1999-11-16 | Augustine Medical, Inc. | Normothermic heater wound covering |
US5534021A (en) * | 1994-09-01 | 1996-07-09 | Dvoretzky; Israel | Heating pad for providing heat therapy |
US5817145A (en) * | 1994-11-21 | 1998-10-06 | Augustine Medical, Inc. | Wound treatment device |
US5601839A (en) * | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
ES2167572T3 (es) * | 1995-06-29 | 2002-05-16 | Procter & Gamble | Celulas de calor. |
US5662096A (en) * | 1995-07-03 | 1997-09-02 | Omni Therm, Inc. | Trigger to activate supercooled aqueous salt solution for use in a heat pack |
US6245347B1 (en) * | 1995-07-28 | 2001-06-12 | Zars, Inc. | Methods and apparatus for improved administration of pharmaceutically active compounds |
US5697962A (en) * | 1995-09-29 | 1997-12-16 | Dura-Kold Corporation | Therapeutic wrap |
DK0855888T3 (da) * | 1995-10-03 | 2003-02-17 | Tru Fit Marketing Corp | Terapeutisk elastisk kropsstøtte |
US5935157A (en) * | 1997-09-18 | 1999-08-10 | Harmon; Susan | Therapeutic cold pack for hand, wrist and forearm |
DE69908027T2 (de) * | 1998-07-10 | 2004-04-08 | Becton, Dickinson And Co. | Ellbogenstütze mit bewegbarer Lasche |
-
2001
- 2001-01-08 US US09/756,059 patent/US20010049546A1/en not_active Abandoned
- 2001-02-02 CA CA002398543A patent/CA2398543A1/fr not_active Abandoned
- 2001-02-02 EP EP01908795A patent/EP1255519B1/fr not_active Expired - Lifetime
- 2001-02-02 AU AU36627/01A patent/AU778280B2/en not_active Ceased
- 2001-02-02 DE DE60112248T patent/DE60112248T2/de not_active Expired - Fee Related
- 2001-02-02 AT AT01908795T patent/ATE300262T1/de not_active IP Right Cessation
- 2001-02-02 ES ES01908795T patent/ES2247064T3/es not_active Expired - Lifetime
- 2001-02-02 WO PCT/US2001/003432 patent/WO2001058408A2/fr active IP Right Grant
-
2003
- 2003-07-01 US US10/612,102 patent/US20040097864A1/en not_active Abandoned
-
2005
- 2005-03-22 US US11/087,492 patent/US20050208115A1/en not_active Abandoned
Cited By (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070123960A1 (en) * | 2001-09-17 | 2007-05-31 | Rousmaniere Sharon O | Product and method for reduction of skin itch discomfort, and disease |
US20060276863A1 (en) * | 2003-05-09 | 2006-12-07 | Kao Corporation | Warming tool |
US8197526B2 (en) * | 2003-05-09 | 2012-06-12 | Kao Corporation | Warming tool |
US20090287280A1 (en) * | 2008-05-15 | 2009-11-19 | Wyeth | Portable moist heat system |
US9566186B2 (en) | 2008-05-15 | 2017-02-14 | Wyeth Llc | Portable moist heat system |
US8430921B2 (en) * | 2008-05-15 | 2013-04-30 | Wyeth | Portable moist heat system |
US9060850B2 (en) | 2009-01-23 | 2015-06-23 | Forever Young International, Inc. | Method and system for making an apparatus for individualized area-specific skin treatments for a subject |
US8372130B2 (en) * | 2009-01-23 | 2013-02-12 | Forever Young International, Inc. | Temperature controlled facial mask with area-specific treatments |
US20100191314A1 (en) * | 2009-01-23 | 2010-07-29 | Young Daniel L | Temperature controlled facial mask with area-specific treatments |
US10064751B2 (en) | 2009-01-23 | 2018-09-04 | Forever Young International, Inc. | Method and system for making an apparatus for individualized area-specific skin treatments for a subject |
US9351870B2 (en) | 2009-01-23 | 2016-05-31 | Forever Young International, Inc. | Method and system for making an apparatus for individualized area-specific skin treatments for a subject |
US10596028B2 (en) | 2009-07-26 | 2020-03-24 | Forever Young International, Inc. | Self-heated consumer spa products and applications thereof |
US9730832B2 (en) | 2009-07-26 | 2017-08-15 | Forever Young International, Inc. | Self-heated consumer spa products and applications thereof |
US20110040235A1 (en) * | 2009-08-11 | 2011-02-17 | Castel J Chris | Multi-Modal Drug Delivery System |
US8523791B2 (en) | 2009-08-11 | 2013-09-03 | Laboratoire Naturel Paris, Llc | Multi-modal drug delivery system |
US20130006337A1 (en) * | 2010-02-04 | 2013-01-03 | Americo Fernandes | Chemical warming device and method for the treatment of viruses such as herpes |
US20120191022A1 (en) * | 2010-07-23 | 2012-07-26 | Muehlbauer Thomas G | Methods and apparatus for therapeutic application of thermal energy |
US9066781B2 (en) | 2010-07-23 | 2015-06-30 | Avacen, Inc. | Methods and apparatus for therapeutic application of thermal energy |
US8679170B2 (en) * | 2010-07-23 | 2014-03-25 | Avacen, Inc. | Methods and apparatus for therapeutic application of thermal energy |
US9687385B2 (en) | 2013-03-11 | 2017-06-27 | Avacen, Inc. | Methods and apparatus for therapeutic application of thermal energy including blood viscosity adjustment |
US9192509B2 (en) | 2013-03-11 | 2015-11-24 | Avacen, Inc. | Methods and apparatus for therapeutic application of thermal energy including blood viscosity adjustment |
US10537464B2 (en) | 2013-03-11 | 2020-01-21 | Avacen Medical, Inc. | Methods and apparatus for therapeutic application of thermal energy including blood viscosity adjustment |
US20160242958A1 (en) * | 2015-02-20 | 2016-08-25 | Jamie Flora | Thermotherapy devices for the ear |
US20180014969A1 (en) * | 2016-07-15 | 2018-01-18 | Raymond K. Wurapa | Assistive device for remediating inflammation, swelling and pain |
US20180168855A1 (en) * | 2016-12-15 | 2018-06-21 | Penguin Fingers, Llc | Joint compress cold pack |
US11684282B2 (en) | 2017-02-03 | 2023-06-27 | Avacen, Inc. | Systems and methods for evaluating blood circulation and early detection of cardiovascular issues |
Also Published As
Publication number | Publication date |
---|---|
ES2247064T3 (es) | 2006-03-01 |
CA2398543A1 (fr) | 2001-08-16 |
EP1255519A4 (fr) | 2004-03-31 |
EP1255519B1 (fr) | 2005-07-27 |
ATE300262T1 (de) | 2005-08-15 |
US20040097864A1 (en) | 2004-05-20 |
AU3662701A (en) | 2001-08-20 |
WO2001058408A2 (fr) | 2001-08-16 |
EP1255519A2 (fr) | 2002-11-13 |
DE60112248D1 (de) | 2005-09-01 |
US20050208115A1 (en) | 2005-09-22 |
WO2001058408A3 (fr) | 2002-03-07 |
DE60112248T2 (de) | 2006-05-24 |
AU778280B2 (en) | 2004-11-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |