UA93868C2 - Лекарственное средство для перорального введения, kotopoe содержит ингибитор циклооксигеназы-2, и способ его получения - Google Patents

Лекарственное средство для перорального введения, kotopoe содержит ингибитор циклооксигеназы-2, и способ его получения

Info

Publication number
UA93868C2
UA93868C2 UAA200709319A UAA200709319A UA93868C2 UA 93868 C2 UA93868 C2 UA 93868C2 UA A200709319 A UAA200709319 A UA A200709319A UA A200709319 A UAA200709319 A UA A200709319A UA 93868 C2 UA93868 C2 UA 93868C2
Authority
UA
Ukraine
Prior art keywords
agglomerate
inhibitor
medicament
cyclooxygenase
preparation
Prior art date
Application number
UAA200709319A
Other languages
English (en)
Ukrainian (uk)
Inventor
Марине Mopea
Никола Ости
Original Assignee
Ветоквинол
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ветоквинол filed Critical Ветоквинол
Publication of UA93868C2 publication Critical patent/UA93868C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение касается лекарственного средства, предназначенного для перорального введения, которое содержит ингибитор циклооксигеназы-2 и имеет повышенную биодоступность, а также способа получения такого лекарственного средства.Лекарственное средство по изобретению содержит агломерат на базе инертных твердых частиц, состав которых базируется как минимум на одном вспомогательном веществе, причем указанный агломерат содержит ингибитор циклооксигеназы-2 и как минимум один гидрофильный полимер.Согласно изобретению, агломерат содержит аэрозоль, нанесенный �
UAA200709319A 2005-01-24 2006-01-23 Лекарственное средство для перорального введения, kotopoe содержит ингибитор циклооксигеназы-2, и способ его получения UA93868C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0500708A FR2881049B1 (fr) 2005-01-24 2005-01-24 Medicament destine a etre administre par voie orale comprenant un inhibiteur de la cyclo-oxygenase-2, et son procede de preparation

Publications (1)

Publication Number Publication Date
UA93868C2 true UA93868C2 (ru) 2011-03-25

Family

ID=34954944

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200709319A UA93868C2 (ru) 2005-01-24 2006-01-23 Лекарственное средство для перорального введения, kotopoe содержит ингибитор циклооксигеназы-2, и способ его получения

Country Status (17)

Country Link
US (1) US20080213376A1 (ru)
EP (1) EP1845959B1 (ru)
JP (1) JP5106119B2 (ru)
KR (2) KR20080007543A (ru)
CN (1) CN101119712B (ru)
AU (1) AU2006207396B2 (ru)
BR (1) BRPI0607372B8 (ru)
CA (1) CA2595496C (ru)
FR (1) FR2881049B1 (ru)
IL (1) IL184759A (ru)
MX (1) MX2007008878A (ru)
NZ (1) NZ556707A (ru)
PL (1) PL1845959T3 (ru)
RU (1) RU2391099C2 (ru)
UA (1) UA93868C2 (ru)
WO (1) WO2006077334A2 (ru)
ZA (1) ZA200705996B (ru)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU670567B2 (en) * 1992-03-05 1996-07-25 American Home Products Corporation Pharmaceutical coated cores
AR024222A1 (es) * 1998-10-16 2002-09-25 Palau Pharma Sa Imidazoles con actividad antiinflamatoria un procedimiento para su preparacion y composiciones farmaceuticas que lo contienen
AU784572B2 (en) * 1999-12-08 2006-05-04 Pharmacia Corporation Solid-state form of celecoxib having enhanced bioavailability
KR100717549B1 (ko) * 1999-12-22 2007-05-11 파마시아 코포레이션 시클로옥시게나제-2 억제제의 이중-방출 조성물
IL150352A0 (en) * 1999-12-22 2002-12-01 Pharmacia Corp Sustained-release formulation of a cyclooxygenase-2 inhibitor
AU2002221273A1 (en) * 2000-10-26 2002-05-06 Atul M. Mehta Delayed and sustained release formulations and method of use thereof

Also Published As

Publication number Publication date
FR2881049B1 (fr) 2008-12-26
JP5106119B2 (ja) 2012-12-26
US20080213376A1 (en) 2008-09-04
KR20080007543A (ko) 2008-01-22
RU2007132017A (ru) 2009-02-27
CA2595496C (fr) 2014-06-03
CN101119712A (zh) 2008-02-06
BRPI0607372B1 (pt) 2019-04-30
RU2391099C2 (ru) 2010-06-10
PL1845959T3 (pl) 2015-10-30
IL184759A (en) 2012-10-31
ZA200705996B (en) 2009-03-25
WO2006077334A3 (fr) 2007-04-12
EP1845959B1 (fr) 2015-04-15
KR20130128019A (ko) 2013-11-25
BRPI0607372A2 (pt) 2009-09-01
FR2881049A1 (fr) 2006-07-28
CN101119712B (zh) 2013-05-01
AU2006207396B2 (en) 2011-05-19
JP2008528462A (ja) 2008-07-31
EP1845959A2 (fr) 2007-10-24
CA2595496A1 (fr) 2006-07-27
MX2007008878A (es) 2007-10-11
BRPI0607372B8 (pt) 2021-05-25
WO2006077334A2 (fr) 2006-07-27
AU2006207396A1 (en) 2006-07-27
NZ556707A (en) 2010-05-28
IL184759A0 (en) 2007-12-03

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