UA93668C2 - N-(heteroaryl)-1h-indole-2-carboxamide derivatives and their use as vanilloid trpv1 receptor ligands - Google Patents
N-(heteroaryl)-1h-indole-2-carboxamide derivatives and their use as vanilloid trpv1 receptor ligandsInfo
- Publication number
- UA93668C2 UA93668C2 UAA200709046A UAA200709046A UA93668C2 UA 93668 C2 UA93668 C2 UA 93668C2 UA A200709046 A UAA200709046 A UA A200709046A UA A200709046 A UAA200709046 A UA A200709046A UA 93668 C2 UA93668 C2 UA 93668C2
- Authority
- UA
- Ukraine
- Prior art keywords
- indole
- heteroaryl
- receptor ligands
- carboxamide derivatives
- trpv1 receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0550068A FR2880625B1 (fr) | 2005-01-07 | 2005-01-07 | Derives de n-(heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
UA93668C2 true UA93668C2 (en) | 2011-03-10 |
Family
ID=34955041
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200709046A UA93668C2 (en) | 2005-01-07 | 2006-04-01 | N-(heteroaryl)-1h-indole-2-carboxamide derivatives and their use as vanilloid trpv1 receptor ligands |
Country Status (36)
Country | Link |
---|---|
US (2) | US7407950B2 (ru) |
EP (1) | EP1841737B1 (ru) |
JP (1) | JP5242167B2 (ru) |
KR (1) | KR101288698B1 (ru) |
CN (1) | CN101115718B (ru) |
AR (1) | AR052450A1 (ru) |
AT (1) | ATE460397T1 (ru) |
AU (1) | AU2006204405B2 (ru) |
BR (1) | BRPI0606472A2 (ru) |
CA (1) | CA2594418C (ru) |
CR (1) | CR9210A (ru) |
CY (1) | CY1110647T1 (ru) |
DE (1) | DE602006012802D1 (ru) |
DK (1) | DK1841737T3 (ru) |
EA (1) | EA013264B1 (ru) |
ES (1) | ES2342318T3 (ru) |
FR (1) | FR2880625B1 (ru) |
HK (1) | HK1117506A1 (ru) |
HR (1) | HRP20100297T1 (ru) |
IL (1) | IL184268A (ru) |
MA (1) | MA29239B1 (ru) |
MX (1) | MX2007008308A (ru) |
MY (1) | MY145932A (ru) |
NO (1) | NO20073811L (ru) |
NZ (1) | NZ556318A (ru) |
PE (1) | PE20061019A1 (ru) |
PL (1) | PL1841737T3 (ru) |
PT (1) | PT1841737E (ru) |
RS (1) | RS51358B (ru) |
SI (1) | SI1841737T1 (ru) |
TN (1) | TNSN07253A1 (ru) |
TW (1) | TWI367879B (ru) |
UA (1) | UA93668C2 (ru) |
UY (1) | UY29327A1 (ru) |
WO (1) | WO2006072736A1 (ru) |
ZA (1) | ZA200705548B (ru) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2874015B1 (fr) * | 2004-08-05 | 2006-09-15 | Sanofi Synthelabo | Derives de n-(1h-indolyl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique |
FR2888847B1 (fr) | 2005-07-22 | 2007-08-31 | Sanofi Aventis Sa | Derives de n-(heteriaryl)-1-heteorarylalkyl-1h-indole-2- carboxamides, leur preparation et application en therapeutique |
FR2903985B1 (fr) | 2006-07-24 | 2008-09-05 | Sanofi Aventis Sa | Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique |
FR2904316B1 (fr) | 2006-07-31 | 2008-09-05 | Sanofi Aventis Sa | Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique. |
AU2007333990A1 (en) * | 2006-12-15 | 2008-06-26 | Janssen Pharmaceutica N.V. | Benzimidazole TRPV1 inhibitors |
FR2911604B1 (fr) | 2007-01-19 | 2009-04-17 | Sanofi Aventis Sa | Derives de n-(heteroaryl-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique |
EP2185560A4 (en) * | 2007-08-10 | 2011-10-05 | Lundbeck & Co As H | HETEROARYLAMIDANALOGE |
WO2009089057A1 (en) * | 2008-01-09 | 2009-07-16 | Renovis, Ins. | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
FR2926556B1 (fr) * | 2008-01-22 | 2010-02-19 | Sanofi Aventis | Derives de carboxamides n-azabicycliques, leur preparation et leur application en therapeutique |
FR2926555B1 (fr) * | 2008-01-22 | 2010-02-19 | Sanofi Aventis | Derives bicycliques de carboxamides azabicycliques, leur preparation et leur application en therapeutique |
FR2926554B1 (fr) * | 2008-01-22 | 2010-03-12 | Sanofi Aventis | Derives de carboxamides azabicycliques, leur preparation et leur application en therapeutique |
US20120027693A1 (en) | 2010-07-27 | 2012-02-02 | Bean Bruce P | Methods and compositions for preventing and relieving muscle cramps and for recovery from neuromuscular irritability and fatigue following exercise |
KR101293384B1 (ko) * | 2010-10-13 | 2013-08-05 | 주식회사 대웅제약 | 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도 |
EP3570861A4 (en) | 2017-01-23 | 2020-11-18 | Flex Pharma, Inc. | COMPOSITIONS AND PROCEDURES EFFECTING SPORTING PERFORMANCE |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5846990A (en) * | 1995-07-24 | 1998-12-08 | Bristol-Myers Squibb Co. | Substituted biphenyl isoxazole sulfonamides |
AU2262097A (en) * | 1996-02-13 | 1997-09-02 | Abbott Laboratories | Novel benzo-1,3-dioxolyl- and benzofuranyl substituted pyrrolidine derivat ives as endothelin antagonists |
ATE206701T1 (de) * | 1996-04-19 | 2001-10-15 | American Home Prod | Östrogene verbindungen |
TR200101234T2 (tr) * | 1997-08-04 | 2002-06-21 | Abbott Laboratories | Endotelin antagonistleri. |
UA68365C2 (en) * | 1997-11-06 | 2004-08-16 | Wyeth Corp | Peroral contraception by combination of anti-estrogen and progestin |
RU2225397C2 (ru) * | 1997-12-24 | 2004-03-10 | Авентис Фарма Дойчланд Гмбх | Производные индола как ингибиторы фактора Ха |
PT1076558E (pt) * | 1998-05-15 | 2003-11-28 | Wyeth Corp | 2-fenil-1-¬4-(2-aminoetoxi)-benzil|-indole em combinacao com estrogenios |
CO5180550A1 (es) * | 1999-04-19 | 2002-07-30 | Smithkline Beecham Corp | Inhibidores de fab i |
AR030064A1 (es) * | 2000-07-06 | 2003-08-13 | Wyeth Corp | Metodos para inhibir los efectos uterotroficos de los agentes estrogenicos |
EP1314733A1 (en) * | 2001-11-22 | 2003-05-28 | Aventis Pharma Deutschland GmbH | Indole-2-carboxamides as factor Xa inhibitors |
ES2316777T3 (es) * | 2002-02-15 | 2009-04-16 | Glaxo Group Limited | Moduladores de receptores vainilloides. |
CA2510811A1 (en) * | 2002-12-20 | 2004-07-08 | Bayer Healthcare Ag | Use of substituted 2,5-diamidoindoles for the treatment of urological diseases |
US7531558B2 (en) * | 2003-02-14 | 2009-05-12 | Glaxo Group Limited | Carboxamide derivatives |
AR045979A1 (es) * | 2003-04-28 | 2005-11-23 | Astrazeneca Ab | Amidas heterociclicas |
WO2004108133A2 (en) * | 2003-06-05 | 2004-12-16 | Vertex Pharmaceuticals Incorporated | Modulators of vr1 receptor |
US7544803B2 (en) * | 2004-01-23 | 2009-06-09 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
FR2874015B1 (fr) * | 2004-08-05 | 2006-09-15 | Sanofi Synthelabo | Derives de n-(1h-indolyl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique |
-
2005
- 2005-01-07 FR FR0550068A patent/FR2880625B1/fr not_active Expired - Fee Related
-
2006
- 2006-01-04 RS RSP-2010/0259A patent/RS51358B/en unknown
- 2006-01-04 PT PT06704665T patent/PT1841737E/pt unknown
- 2006-01-04 ZA ZA200705548A patent/ZA200705548B/xx unknown
- 2006-01-04 EA EA200701451A patent/EA013264B1/ru not_active IP Right Cessation
- 2006-01-04 JP JP2007549933A patent/JP5242167B2/ja not_active Expired - Fee Related
- 2006-01-04 PL PL06704665T patent/PL1841737T3/pl unknown
- 2006-01-04 WO PCT/FR2006/000008 patent/WO2006072736A1/fr active Application Filing
- 2006-01-04 DE DE602006012802T patent/DE602006012802D1/de active Active
- 2006-01-04 CN CN2006800042385A patent/CN101115718B/zh not_active Expired - Fee Related
- 2006-01-04 ES ES06704665T patent/ES2342318T3/es active Active
- 2006-01-04 NZ NZ556318A patent/NZ556318A/en not_active IP Right Cessation
- 2006-01-04 EP EP06704665A patent/EP1841737B1/fr active Active
- 2006-01-04 DK DK06704665.6T patent/DK1841737T3/da active
- 2006-01-04 AT AT06704665T patent/ATE460397T1/de active
- 2006-01-04 CA CA2594418A patent/CA2594418C/fr not_active Expired - Fee Related
- 2006-01-04 PE PE2006000037A patent/PE20061019A1/es not_active Application Discontinuation
- 2006-01-04 AR ARP060100023A patent/AR052450A1/es unknown
- 2006-01-04 AU AU2006204405A patent/AU2006204405B2/en not_active Ceased
- 2006-01-04 KR KR1020077018041A patent/KR101288698B1/ko not_active IP Right Cessation
- 2006-01-04 SI SI200630674T patent/SI1841737T1/sl unknown
- 2006-01-04 MX MX2007008308A patent/MX2007008308A/es active IP Right Grant
- 2006-01-04 BR BRPI0606472-8A patent/BRPI0606472A2/pt not_active Application Discontinuation
- 2006-01-04 MY MYPI20060030A patent/MY145932A/en unknown
- 2006-01-05 UY UY29327A patent/UY29327A1/es not_active Application Discontinuation
- 2006-01-06 TW TW095100688A patent/TWI367879B/zh not_active IP Right Cessation
- 2006-04-01 UA UAA200709046A patent/UA93668C2/ru unknown
-
2007
- 2007-06-20 US US11/765,687 patent/US7407950B2/en not_active Expired - Fee Related
- 2007-06-26 CR CR9210A patent/CR9210A/es unknown
- 2007-06-27 IL IL184268A patent/IL184268A/en not_active IP Right Cessation
- 2007-07-03 TN TNP2007000253A patent/TNSN07253A1/fr unknown
- 2007-07-20 NO NO20073811A patent/NO20073811L/no not_active Application Discontinuation
- 2007-07-26 MA MA30112A patent/MA29239B1/fr unknown
-
2008
- 2008-06-20 US US12/143,066 patent/US7557134B2/en not_active Expired - Fee Related
- 2008-07-17 HK HK08107936.4A patent/HK1117506A1/xx not_active IP Right Cessation
-
2010
- 2010-05-26 HR HR20100297T patent/HRP20100297T1/hr unknown
- 2010-06-01 CY CY20101100482T patent/CY1110647T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UA93668C2 (en) | N-(heteroaryl)-1h-indole-2-carboxamide derivatives and their use as vanilloid trpv1 receptor ligands | |
MXPA04002983A (es) | Derivados de quinuclidina, procedimientos para prepararlos y sus usos como inhibidores del receptor muscar??nico m2 y/o m3. | |
ATE438633T1 (de) | Benzo (d) isoxazol-3-yl-amin- verbindungen und deren verwendung als vanilloid-rezeptor liganden | |
ATE433447T1 (de) | Pyrimiidinverbindungen | |
ATE524433T1 (de) | Trpv1 agonisten , zubereitungen die diese enthalten und ihre anwendung | |
NO20066015L (no) | Fuserte heterosykliske forbindelser | |
NO20064763L (no) | Forbindelser og fremgangsmater for behandling av dyslipidemi | |
NO20075169L (no) | Nye imidazo (1,5-A)pyndindenvater, fremgangsmate for fremstilling og farmasoytiske sammensetninger som inneholder samme. | |
EA200700099A1 (ru) | Производные пиридина | |
TW200732339A (en) | Nitrogen-containing bicyclic heteroaryl compounds and methods of use | |
NO20075624L (no) | Nye histamin H3-reseptorligander og deres terapeutiske anvendelser | |
PL1877364T3 (pl) | Pochodne fenyloacetylenu o powinowactwie do receptora mGluR5 | |
PE20061436A1 (es) | Derivados de amida sustituida como inhibidores de proteina quinasa | |
EA200870360A1 (ru) | Бензимидазолы, обладающие активностью в отношении рецепторов м1, и их применение в медицине | |
BRPI0507495A (pt) | composto, composição farmacêutica, uso do composto método para o tratamento de distúrbios mediados por mglur5, e, método para inibir a ativação de receptores de mglur5 | |
DK1725536T3 (da) | Imidazolin-derivater med CB1-antagonistisk aktivitet | |
ATE445593T1 (de) | Acetylenderivate | |
GB0129476D0 (en) | Organic compounds | |
TW200638930A (en) | Acetylene derivatives | |
ATE541839T1 (de) | Pyrrolidiniumderivate als m3-muskarinische rezeptoren | |
EA201101566A1 (ru) | Производные имидазола и их применение в качестве модуляторов циклинзависимых киназ | |
MX2007007025A (es) | Nuevos derivados de hidantoina como inhibidores de metaloproteinasa. | |
WO2008079683A3 (en) | N- (5, 6, 7, 8-tetrahydronaphthalen-1-yl) urea derivatives and related compounds as trpv1 vanilloid receptor antagonists for the treatment of pain | |
ATE543803T1 (de) | 3-ä2-(3-azylamino-2-oxo-2h-pyridin-1- yl)acetylaminoü-4-oxopentansäurederivate und deren verwendung als caspase-inhibitoren | |
PL376324A1 (en) | Piperazinyl and diazapanyl benzamides and benzthioamides |