UA88910C2 - Гетероциклические соединения для предотвращения или ослабления симптомов заболеваний, которые лечатся коноплей, и способы их получения - Google Patents

Гетероциклические соединения для предотвращения или ослабления симптомов заболеваний, которые лечатся коноплей, и способы их получения

Info

Publication number
UA88910C2
UA88910C2 UAA200700981A UAA200700981A UA88910C2 UA 88910 C2 UA88910 C2 UA 88910C2 UA A200700981 A UAA200700981 A UA A200700981A UA A200700981 A UAA200700981 A UA A200700981A UA 88910 C2 UA88910 C2 UA 88910C2
Authority
UA
Ukraine
Prior art keywords
processes
reduction
preparation
treatment
diseases associated
Prior art date
Application number
UAA200700981A
Other languages
English (en)
Ukrainian (uk)
Inventor
Брей Бхушан Лохрей
Видья Бхушан Лохрей
Брайджеш Шривастава
Original Assignee
Кадила Хелткере Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кадила Хелткере Лимитед filed Critical Кадила Хелткере Лимитед
Publication of UA88910C2 publication Critical patent/UA88910C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Это изобретение касается новых соединений общей формулы (), а также их региоизомеров, таутомерных форм и новых промежуточных продуктов, которые принимают участие в их синтезе. Это изобретение касается также способа получения соединений общей формулы (), их региоизомеров, таутомерных форм, фармацевтически приемлемых солей, фармацевтических композиций, которые содержат такие соединения, и новых промежуточных продуктов, которые принимают участие в их синтезе.()
UAA200700981A 2004-07-12 2005-07-08 Гетероциклические соединения для предотвращения или ослабления симптомов заболеваний, которые лечатся коноплей, и способы их получения UA88910C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN745MU2004 2004-07-12

Publications (1)

Publication Number Publication Date
UA88910C2 true UA88910C2 (ru) 2009-12-10

Family

ID=35636669

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200700981A UA88910C2 (ru) 2004-07-12 2005-07-08 Гетероциклические соединения для предотвращения или ослабления симптомов заболеваний, которые лечатся коноплей, и способы их получения

Country Status (20)

Country Link
US (2) US8030345B2 (ru)
EP (2) EP2343302A1 (ru)
JP (1) JP2008505965A (ru)
KR (1) KR20070041717A (ru)
CN (1) CN101014605A (ru)
AP (1) AP2228A (ru)
AU (1) AU2005278781B2 (ru)
BR (1) BRPI0513104A (ru)
CA (1) CA2586011C (ru)
EA (1) EA011307B1 (ru)
EC (1) ECSP077167A (ru)
GE (1) GEP20094682B (ru)
IL (1) IL180637A0 (ru)
MX (1) MX2007000491A (ru)
NO (1) NO20070299L (ru)
NZ (2) NZ552670A (ru)
TN (1) TNSN07006A1 (ru)
UA (1) UA88910C2 (ru)
WO (1) WO2006025069A2 (ru)
ZA (1) ZA200700162B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ552670A (en) * 2004-07-12 2010-02-26 Cadila Healthcare Ltd Tricyclic pyrazole derivatives as cannabinoid receptor modulators
SG178907A1 (en) 2009-08-28 2012-04-27 Arena Pharm Inc Cannabinoid receptor modulators
EP4166552A1 (en) 2011-02-25 2023-04-19 Arena Pharmaceuticals, Inc. Crystalline forms and processes for the preparation of condensed azacycles (cannabinoid receptor modulators)
US9597340B2 (en) 2011-02-25 2017-03-21 Arena Pharmaceuticals, Inc. Cannabinoid receptor modulators
ES2929977T3 (es) * 2011-02-25 2022-12-05 Arena Pharm Inc Moduladores del receptor cannabinoide
JP6691552B2 (ja) * 2015-04-30 2020-04-28 ノバルティス アーゲー ファルネソイドｘ受容体をモジュレートするのに有用である縮合三環式ピラゾール誘導体
EP3402780A1 (en) 2016-01-14 2018-11-21 Beth Israel Deaconess Medical Center, Inc. Mast-cell modulators and uses thereof
WO2019145919A1 (en) * 2018-01-29 2019-08-01 Cadila Healthcare Limited Heterocyclic compounds useful as antibacterial agents

Family Cites Families (26)

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US3260721A (en) * 1962-04-10 1966-07-12 American Cyanamid Co Heterocyclic derivatives of yohimbe alkaloids
DK7779A (da) * 1978-01-16 1979-07-17 Sandoz Ag Fremgangsmaade til fremstilling af pnenicilliner eller cephalosporiner
EP0122952B1 (en) 1983-04-22 1987-10-28 Mitsubishi Rayon Co., Ltd. Apparatus for measuring gas partial pressure in living body
FR2692575B1 (fr) 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2713225B1 (fr) 1993-12-02 1996-03-01 Sanofi Sa N-pipéridino-3-pyrazolecarboxamide substitué.
CA2106642C (en) * 1992-10-14 2005-08-16 Peter Bod Carbazolone derivatives and process for preparing the same
FR2714057B1 (fr) 1993-12-17 1996-03-08 Sanofi Elf Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
US5547975A (en) 1994-09-20 1996-08-20 Talley; John J. Benzopyranopyrazolyl derivatives for the treatment of inflammation
FR2741621B1 (fr) 1995-11-23 1998-02-13 Sanofi Sa Nouveaux derives de pyrazole, procede pour leur preparation et compositions pharmaceutiques en contenant
FR2742148B1 (fr) 1995-12-08 1999-10-22 Sanofi Sa Nouveaux derives du pyrazole-3-carboxamide, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2758723B1 (fr) 1997-01-28 1999-04-23 Sanofi Sa Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments
FR2761266B1 (fr) 1997-03-28 1999-07-02 Sanofi Sa Composition pharmaceutique formee par granulation humide pour l'administration orale d'un derive du n-piperidino-3- pyrazolecarboxamide, de ses sels et de leurs solvates
FR2789079B3 (fr) 1999-02-01 2001-03-02 Sanofi Synthelabo Derive d'acide pyrazolecarboxylique, sa preparation, les compositions pharmaceutiques en contenant
FR2800372B1 (fr) * 1999-11-03 2001-12-07 Sanofi Synthelabo Derives tricycliques d'acide 1-benzylpyrazole-3- carboxylique, leur preparation, les medicaments en contenant
FR2800375B1 (fr) 1999-11-03 2004-07-23 Sanofi Synthelabo Derives tricycliques d'acide pyrazolecarboxylique, leur preparation, les compositions pharmaceutiques en contenant
FR2804604B1 (fr) 2000-02-09 2005-05-27 Sanofi Synthelabo Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles pour faciliter l'arret de la consommation de tabac
FR2809621B1 (fr) 2000-05-12 2002-09-06 Sanofi Synthelabo Utilisation d'un antagoniste des recepteurs aux cannabinoides centraux pour la preparation de medicaments utiles comme antidiarrheiques
FR2816938B1 (fr) 2000-11-22 2003-01-03 Sanofi Synthelabo Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant
AU2002331766A1 (en) 2001-08-31 2003-03-18 University Of Connecticut Novel pyrazole analogs acting on cannabinoid receptors
DE60215960T2 (de) 2001-09-21 2007-03-01 Solvay Pharmaceuticals B.V. Neue 4,5-dihydro-1h-pyrazol-derivate mit cb1-antagonistischer wirkung
CA2442245C (en) 2001-09-21 2010-03-30 Solvay Pharmaceuticals B.V. 4,5-dihydro-1h-pyrazole derivatives having potent cb1-antagonistic activity
TWI231757B (en) 2001-09-21 2005-05-01 Solvay Pharm Bv 1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
US6509367B1 (en) 2001-09-22 2003-01-21 Virginia Commonwealth University Pyrazole cannabinoid agonist and antagonists
BR0307796A (pt) * 2002-02-19 2004-12-21 Pharmacia Corp Derivados tricìclicos de pirazol para o tratamento de inflamação
ITMI20041033A1 (it) * 2004-05-24 2004-08-24 Neuroscienze S C A R L Composti farmaceutici
NZ552670A (en) * 2004-07-12 2010-02-26 Cadila Healthcare Ltd Tricyclic pyrazole derivatives as cannabinoid receptor modulators

Also Published As

Publication number Publication date
CN101014605A (zh) 2007-08-08
WO2006025069A2 (en) 2006-03-09
GEP20094682B (en) 2009-05-10
WO2006025069A8 (en) 2007-03-15
EA200700246A1 (ru) 2007-08-31
US20100273791A1 (en) 2010-10-28
KR20070041717A (ko) 2007-04-19
BRPI0513104A (pt) 2008-04-29
ECSP077167A (es) 2007-05-30
MX2007000491A (es) 2007-03-28
AU2005278781B2 (en) 2009-06-18
JP2008505965A (ja) 2008-02-28
US20080051386A1 (en) 2008-02-28
TNSN07006A1 (en) 2008-06-02
CA2586011C (en) 2011-07-19
EP2343302A1 (en) 2011-07-13
EA011307B1 (ru) 2009-02-27
ZA200700162B (en) 2009-09-30
NZ552670A (en) 2010-02-26
IL180637A0 (en) 2007-06-03
AP2228A (en) 2011-04-01
US8030345B2 (en) 2011-10-04
CA2586011A1 (en) 2006-03-09
NZ580387A (en) 2011-06-30
WO2006025069A3 (en) 2006-04-27
NO20070299L (no) 2007-03-26
AP2007003880A0 (en) 2007-02-28
EP1781668A2 (en) 2007-05-09
AU2005278781A1 (en) 2006-03-09

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