UA79940C2 - Carbonylbenzoxazine compounds for enhancing of glutamatergic synaptic responses - Google Patents
Carbonylbenzoxazine compounds for enhancing of glutamatergic synaptic responses Download PDFInfo
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- UA79940C2 UA79940C2 UA20040503965A UA20040503965A UA79940C2 UA 79940 C2 UA79940 C2 UA 79940C2 UA 20040503965 A UA20040503965 A UA 20040503965A UA 20040503965 A UA20040503965 A UA 20040503965A UA 79940 C2 UA79940 C2 UA 79940C2
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- substituted
- alkyl
- cycloalkyl
- compound according
- aryl
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33333401P | 2001-11-26 | 2001-11-26 | |
| PCT/US2002/037646 WO2003045315A2 (en) | 2001-11-26 | 2002-11-25 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA79940C2 true UA79940C2 (en) | 2007-08-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA20040503965A UA79940C2 (en) | 2001-11-26 | 2002-11-25 | Carbonylbenzoxazine compounds for enhancing of glutamatergic synaptic responses |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7799913B2 (ru) |
| EP (1) | EP1448537A4 (ru) |
| JP (1) | JP4620349B2 (ru) |
| KR (1) | KR100915176B1 (ru) |
| CN (1) | CN1620440A (ru) |
| AU (1) | AU2002352886B2 (ru) |
| BR (1) | BR0214425A (ru) |
| CA (1) | CA2463592A1 (ru) |
| CZ (1) | CZ2004632A3 (ru) |
| EA (1) | EA011034B1 (ru) |
| GE (1) | GEP20063859B (ru) |
| HR (1) | HRP20040424A2 (ru) |
| HU (1) | HUP0402279A3 (ru) |
| IL (1) | IL161452A0 (ru) |
| MA (1) | MA26233A1 (ru) |
| MX (1) | MXPA04004815A (ru) |
| NO (1) | NO20041590L (ru) |
| NZ (1) | NZ532368A (ru) |
| PL (1) | PL371722A1 (ru) |
| SK (1) | SK2292004A3 (ru) |
| UA (1) | UA79940C2 (ru) |
| WO (1) | WO2003045315A2 (ru) |
| ZA (1) | ZA200403729B (ru) |
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| AU2007342364A1 (en) * | 2007-01-03 | 2008-07-17 | Cortex Pharmaceuticals, Inc. | 3-substituted-[1,2,3]benzotriazinone compounds for enhancing glutamatergic synaptic responses |
| NZ578293A (en) * | 2007-01-03 | 2012-01-12 | Cortex Pharma Inc | 3-substituted-[1,2,3]-benzotriazinone compound for enhancing glutamatergic synaptic responses |
| US20130058915A1 (en) | 2010-03-02 | 2013-03-07 | Children's Medica Center Corporation | Methods and compositions for treatment of angelman syndrome and autism spectrum disorders |
| AU2012267622B2 (en) * | 2011-06-08 | 2017-06-22 | Sunovion Pharmaceuticals, Inc. | Metabotropic glutamate receptor 5 modulators and methods of use thereof |
| BR112015031249A2 (pt) | 2013-06-13 | 2017-07-25 | Veroscience Llc | método de tratamento, método para tratar um distúrbio metabólico ou um elemento chave do mesmo, método para normalizar um ritmo diário de liberação de dopamina no sumn, método para estimular a liberação de dopamina de neurônios dopaminérgicos no sumn de um indivíduo e composição farmacêutica |
| PE20180500A1 (es) | 2015-06-26 | 2018-03-09 | Takeda Pharmaceuticals Co | Derivados de 2,3-dihidro-4h-1,3-benzoxazin-4-ona como moduladores del receptor muscarinico colinergico m1 |
| US10548899B2 (en) | 2015-10-20 | 2020-02-04 | Takeda Pharmaceutical Company Limited | Quinazolinone and benzotriazinone compounds with cholinergic muscarinin M1 receptor positive allosteric modulator activity |
| CA3075477A1 (en) | 2017-08-07 | 2019-02-14 | Joint Stock Company "Biocad" | Novel heterocyclic compounds as cdk8/19 inhibitors |
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|---|---|---|---|---|
| US2943087A (en) * | 1960-06-28 | n naoh | ||
| DE1122531B (de) * | 1957-09-13 | 1962-01-25 | Thomae Gmbh Dr K | Verfahren zur Herstellung von therapeutisch wertvollen 4-Oxo-2-(halogenalkyl)-2,3-dihydro-benzoxazinen-(1,3) |
| US4022139A (en) * | 1975-10-28 | 1977-05-10 | Blue Bell, Inc. | Tacker guide and method |
| EP0010348A1 (en) * | 1978-09-12 | 1980-04-30 | Imperial Chemical Industries Plc | Heterocyclic trichloromethyl derivatives, process for their preparation and their use |
| JPH0597824A (ja) * | 1990-09-25 | 1993-04-20 | Takeda Chem Ind Ltd | １，３−ベンゾオキサジン誘導体 |
| AU688271B2 (en) | 1992-07-24 | 1998-03-12 | Regents Of The University Of California, The | Drugs that enhance synaptic responses mediated by ampa receptors |
| US5650409A (en) * | 1995-06-02 | 1997-07-22 | Cortex Pharmaceuticals, Inc. | Benzoyl piperidines/pyrrolidines for enhancing synaptic response |
| US5736543A (en) * | 1996-04-03 | 1998-04-07 | The Regents Of The University Of California | Benzoxazines for enhancing synaptic response |
| GB9716962D0 (en) * | 1997-08-12 | 1997-10-15 | Univ Birmingham | Liver function test |
| WO1999016758A1 (en) * | 1997-10-27 | 1999-04-08 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them |
| TR200002427T2 (tr) * | 1998-02-18 | 2001-01-22 | Neurosearch A/S | Yeni bileşikler ve bunların pozitif ampa reseptör modülatörleri olarak kullanımı. |
| US6124278A (en) * | 1998-04-03 | 2000-09-26 | The Regents Of The University Of California | Acylbenzoxazines for enhancing synaptic response |
-
2002
- 2002-11-25 WO PCT/US2002/037646 patent/WO2003045315A2/en active Application Filing
- 2002-11-25 AU AU2002352886A patent/AU2002352886B2/en not_active Ceased
- 2002-11-25 SK SK229-2004A patent/SK2292004A3/sk not_active Application Discontinuation
- 2002-11-25 IL IL16145202A patent/IL161452A0/xx unknown
- 2002-11-25 US US10/495,049 patent/US7799913B2/en not_active Expired - Fee Related
- 2002-11-25 JP JP2003546820A patent/JP4620349B2/ja not_active Expired - Fee Related
- 2002-11-25 BR BR0214425-5A patent/BR0214425A/pt not_active Application Discontinuation
- 2002-11-25 EP EP02789846A patent/EP1448537A4/en not_active Withdrawn
- 2002-11-25 NZ NZ532368A patent/NZ532368A/en not_active IP Right Cessation
- 2002-11-25 KR KR1020047007502A patent/KR100915176B1/ko not_active IP Right Cessation
- 2002-11-25 HU HU0402279A patent/HUP0402279A3/hu unknown
- 2002-11-25 PL PL02371722A patent/PL371722A1/xx not_active Application Discontinuation
- 2002-11-25 MX MXPA04004815A patent/MXPA04004815A/es active IP Right Grant
- 2002-11-25 CA CA002463592A patent/CA2463592A1/en not_active Abandoned
- 2002-11-25 CN CNA028234502A patent/CN1620440A/zh active Pending
- 2002-11-25 GE GE5593A patent/GEP20063859B/en unknown
- 2002-11-25 EA EA200400584A patent/EA011034B1/ru not_active IP Right Cessation
- 2002-11-25 UA UA20040503965A patent/UA79940C2/uk unknown
- 2002-11-25 CZ CZ2004632A patent/CZ2004632A3/cs unknown
-
2004
- 2004-04-19 NO NO20041590A patent/NO20041590L/no not_active Application Discontinuation
- 2004-05-12 HR HR20040424A patent/HRP20040424A2/xx not_active Application Discontinuation
- 2004-05-14 ZA ZA200403729A patent/ZA200403729B/en unknown
- 2004-05-21 MA MA27691A patent/MA26233A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002352886B2 (en) | 2008-10-16 |
| MXPA04004815A (es) | 2005-02-17 |
| EA011034B1 (ru) | 2008-12-30 |
| WO2003045315A2 (en) | 2003-06-05 |
| CA2463592A1 (en) | 2003-06-05 |
| GEP20063859B (en) | 2006-06-26 |
| WO2003045315A3 (en) | 2003-08-28 |
| AU2002352886A1 (en) | 2003-06-10 |
| KR20040054777A (ko) | 2004-06-25 |
| EP1448537A4 (en) | 2005-05-04 |
| CZ2004632A3 (cs) | 2004-08-18 |
| JP4620349B2 (ja) | 2011-01-26 |
| NZ532368A (en) | 2006-10-27 |
| PL371722A1 (en) | 2005-06-27 |
| ZA200403729B (en) | 2005-05-19 |
| EA200400584A1 (ru) | 2005-02-24 |
| US20040259871A1 (en) | 2004-12-23 |
| IL161452A0 (en) | 2004-09-27 |
| JP2005510532A (ja) | 2005-04-21 |
| HUP0402279A2 (hu) | 2005-02-28 |
| KR100915176B1 (ko) | 2009-09-03 |
| BR0214425A (pt) | 2004-11-03 |
| HRP20040424A2 (en) | 2005-06-30 |
| US7799913B2 (en) | 2010-09-21 |
| CN1620440A (zh) | 2005-05-25 |
| EP1448537A2 (en) | 2004-08-25 |
| NO20041590L (no) | 2004-07-12 |
| SK2292004A3 (en) | 2004-09-08 |
| HUP0402279A3 (en) | 2008-09-29 |
| MA26233A1 (fr) | 2004-07-01 |
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