UA75520C2 - Fluorosubstituted cycloalkanoindoles, a composition containing them - Google Patents

Fluorosubstituted cycloalkanoindoles, a composition containing them Download PDF

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Publication number
UA75520C2
UA75520C2 UA20040807066A UA20040807066A UA75520C2 UA 75520 C2 UA75520 C2 UA 75520C2 UA 20040807066 A UA20040807066 A UA 20040807066A UA 20040807066 A UA20040807066 A UA 20040807066A UA 75520 C2 UA75520 C2 UA 75520C2
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compound
formula
acid
compounds
solution
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UA20040807066A
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English (en)
Ukrainian (uk)
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Merck Frosst Canada Inc
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Publication of UA75520C2 publication Critical patent/UA75520C2/uk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06Antiabortive agents; Labour repressants
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    • A61P19/00Drugs for skeletal disorders
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
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    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Transplantation (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
UA20040807066A 2002-01-24 2003-01-22 Fluorosubstituted cycloalkanoindoles, a composition containing them UA75520C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35138402P 2002-01-24 2002-01-24
PCT/CA2003/000084 WO2003062200A2 (en) 2002-01-24 2003-01-22 Fluoro substituted cycloalkanoindoles and their use as prostaglandin d2 receptor antagonists

Publications (1)

Publication Number Publication Date
UA75520C2 true UA75520C2 (en) 2006-04-17

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ID=27613492

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UA20040807066A UA75520C2 (en) 2002-01-24 2003-01-22 Fluorosubstituted cycloalkanoindoles, a composition containing them

Country Status (39)

Country Link
US (6) US20030158246A1 (ru)
EP (3) EP2045241B1 (ru)
JP (2) JP4008885B2 (ru)
KR (2) KR100859230B1 (ru)
CN (3) CN101092388A (ru)
AR (1) AR038136A1 (ru)
AT (1) ATE414690T1 (ru)
AU (1) AU2003202343B2 (ru)
BR (1) BR0307050A (ru)
CA (1) CA2471952C (ru)
CY (3) CY1108841T1 (ru)
DE (2) DE60324767D1 (ru)
DK (2) DK2045241T3 (ru)
DO (1) DOP2003000566A (ru)
EA (1) EA006134B1 (ru)
EC (1) ECSP045203A (ru)
EG (1) EG24978A (ru)
ES (2) ES2316717T3 (ru)
FR (1) FR09C0010I2 (ru)
GE (1) GEP20074078B (ru)
HR (1) HRP20040665B1 (ru)
IL (3) IL162825A0 (ru)
IS (2) IS2633B (ru)
JO (1) JO2481B1 (ru)
LU (1) LU91534I2 (ru)
MX (1) MXPA04007167A (ru)
MY (1) MY137040A (ru)
NL (1) NL300377I2 (ru)
NO (3) NO327322B1 (ru)
NZ (1) NZ533786A (ru)
PE (1) PE20030982A1 (ru)
PL (1) PL208527B1 (ru)
PT (2) PT1470107E (ru)
RS (2) RS20100338A (ru)
SI (2) SI1470107T1 (ru)
TW (1) TWI259080B (ru)
UA (1) UA75520C2 (ru)
WO (1) WO2003062200A2 (ru)
ZA (1) ZA200404999B (ru)

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