UA72875C2 - Translated By PlajБЕЛКИ, КОТОРЫЕ СВЯЗЫВАЮТСЯ С b -амИлоИднЫм ПЕПТИДОМ И ПОЛИНУКЛЕОТИДЫ, КОТОРЫЕ ИХ КОДИРУЮТ - Google Patents

Translated By PlajБЕЛКИ, КОТОРЫЕ СВЯЗЫВАЮТСЯ С b -амИлоИднЫм ПЕПТИДОМ И ПОЛИНУКЛЕОТИДЫ, КОТОРЫЕ ИХ КОДИРУЮТ

Info

Publication number
UA72875C2
UA72875C2 UA99116193A UA99116193A UA72875C2 UA 72875 C2 UA72875 C2 UA 72875C2 UA 99116193 A UA99116193 A UA 99116193A UA 99116193 A UA99116193 A UA 99116193A UA 72875 C2 UA72875 C2 UA 72875C2
Authority
UA
Ukraine
Prior art keywords
polynucleotides
encode
sub
amyloid peptide
bind human
Prior art date
Application number
UA99116193A
Other languages
English (en)
Ukrainian (uk)
Inventor
Бредлі Елтон Озенбергер
Ейлін Марі Кажковскі
Джек Стівен Джекобсен
Джонатан Адам Бард
Стефен Гленн Волкер
Хейді Софіа
Original Assignee
Уайт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Уайт filed Critical Уайт
Publication of UA72875C2 publication Critical patent/UA72875C2/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Описаны новые белки, которые связывают -амилоидный пептид человека, полинуклеотиды, которые кодируют эти белки, и способы продуцирования этих белков. Представлены также диагностические, терапевтические методы и методы скрининга, которые используют полинуклеотиды и полипептиды согласно настоящему изобретению.
UA99116193A 1997-04-16 1998-04-14 Translated By PlajБЕЛКИ, КОТОРЫЕ СВЯЗЫВАЮТСЯ С b -амИлоИднЫм ПЕПТИДОМ И ПОЛИНУКЛЕОТИДЫ, КОТОРЫЕ ИХ КОДИРУЮТ UA72875C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6458397P 1997-04-16 1997-04-16
PCT/US1998/007462 WO1998046636A2 (en) 1997-04-16 1998-04-14 β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME

Publications (1)

Publication Number Publication Date
UA72875C2 true UA72875C2 (ru) 2005-05-16

Family

ID=22056941

Family Applications (1)

Application Number Title Priority Date Filing Date
UA99116193A UA72875C2 (ru) 1997-04-16 1998-04-14 Translated By PlajБЕЛКИ, КОТОРЫЕ СВЯЗЫВАЮТСЯ С b -амИлоИднЫм ПЕПТИДОМ И ПОЛИНУКЛЕОТИДЫ, КОТОРЫЕ ИХ КОДИРУЮТ

Country Status (18)

Country Link
EP (1) EP0975753A2 (ru)
JP (3) JP2001523093A (ru)
KR (1) KR20010006393A (ru)
CN (2) CN1196785C (ru)
AU (1) AU740445B2 (ru)
BR (1) BR9808562A (ru)
CA (1) CA2286484A1 (ru)
EA (1) EA004256B1 (ru)
EE (1) EE9900482A (ru)
GE (1) GEP20043386B (ru)
HU (1) HUP0003116A3 (ru)
ID (1) ID24914A (ru)
IL (3) IL132236A0 (ru)
NO (1) NO995062L (ru)
NZ (1) NZ500216A (ru)
SK (1) SK143299A3 (ru)
UA (1) UA72875C2 (ru)
WO (1) WO1998046636A2 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005295B1 (en) 1997-04-16 2006-02-28 Wyeth β-amyloid peptide-binding proteins and polynucleotides encoding the same
US6787319B2 (en) 1997-04-16 2004-09-07 American Home Products Corp. β-amyloid peptide-binding proteins and polynucleotides encoding the same
CA2346008A1 (en) * 1998-10-13 2000-04-20 American Home Products Corporation G-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same
US6455082B1 (en) * 1999-04-26 2002-09-24 Nestec S.A. Shelf-stable calcium fortified milk and dairy products
CA2387646A1 (en) * 1999-10-21 2001-04-26 Kalobios, Inc. A general method for optimizing the expression of heterologous proteins
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
US7807171B2 (en) 2003-07-25 2010-10-05 Ac Immune Sa Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
US9289488B2 (en) 2010-08-12 2016-03-22 Ac Immune Sa Vaccine engineering
EP2632434A1 (en) 2010-10-26 2013-09-04 AC Immune S.A. Liposome-based construct comprising a peptide modified through hydrophobic moieties
CN102060912B (zh) * 2010-11-22 2012-11-14 清华大学 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用
CN111320678B (zh) * 2020-03-09 2023-06-09 安亭生物有限责任公司 抗菌肽突变体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU611122B2 (en) * 1986-11-17 1991-06-06 Scios Nova Inc. Recombinant alzheimer's amyloid protein
IL115743A0 (en) * 1994-10-28 1996-01-19 American Nat Red Cross A mammal with cells containing a transgene and its production
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide

Also Published As

Publication number Publication date
EA004256B1 (ru) 2004-02-26
HUP0003116A2 (hu) 2001-01-29
JP2008253275A (ja) 2008-10-23
BR9808562A (pt) 2000-05-23
IL132236A (en) 2007-03-08
CN1690203A (zh) 2005-11-02
CN1196785C (zh) 2005-04-13
GEP20043386B (en) 2004-02-10
IL132236A0 (en) 2001-03-19
SK143299A3 (en) 2000-09-12
EE9900482A (ru) 2000-06-15
EP0975753A2 (en) 2000-02-02
NO995062D0 (no) 1999-10-15
ID24914A (id) 2000-08-31
KR20010006393A (ko) 2001-01-26
JP2008104465A (ja) 2008-05-08
HUP0003116A3 (en) 2003-03-28
NZ500216A (en) 2001-06-29
CA2286484A1 (en) 1998-10-22
CN1268973A (zh) 2000-10-04
WO1998046636A2 (en) 1998-10-22
JP2001523093A (ja) 2001-11-20
AU7115698A (en) 1998-11-11
NO995062L (no) 1999-12-14
WO1998046636A3 (en) 1999-01-28
AU740445B2 (en) 2001-11-01
IL179047A0 (en) 2007-03-08
EA199900941A1 (ru) 2000-06-26

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