UA66750C2 - Substituted 1-phenylpirazole 3-carboxamides, a method for the preparation thereof and intermediary compounds, pharmaceutical composition having affinity to neurotensin receptors - Google Patents
Substituted 1-phenylpirazole 3-carboxamides, a method for the preparation thereof and intermediary compounds, pharmaceutical composition having affinity to neurotensin receptorsInfo
- Publication number
- UA66750C2 UA66750C2 UA97104992A UA97104992A UA66750C2 UA 66750 C2 UA66750 C2 UA 66750C2 UA 97104992 A UA97104992 A UA 97104992A UA 97104992 A UA97104992 A UA 97104992A UA 66750 C2 UA66750 C2 UA 66750C2
- Authority
- UA
- Ukraine
- Prior art keywords
- carboxamides
- substituted
- phenylpirazole
- affinity
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/10—Hydrazines
- C07C243/22—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/63—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton
- C07C255/65—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to nitrogen atoms
- C07C255/66—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to nitrogen atoms having cyano groups and nitrogen atoms being part of hydrazine or hydrazone groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/47—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having at least one of the sulfo groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9504350A FR2732967B1 (fr) | 1995-04-11 | 1995-04-11 | 1-phenylpyrazole-3-carboxamides substitues, actifs sur la neurotensine, leur preparation, les compositions pharmaceutiques en contenant |
PCT/FR1996/000546 WO1996032382A1 (fr) | 1995-04-11 | 1996-04-11 | 1-phenylpyrazole-3-carboxamides actifs sur les recepteurs de la neurotensine |
Publications (1)
Publication Number | Publication Date |
---|---|
UA66750C2 true UA66750C2 (en) | 2004-06-15 |
Family
ID=9478010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA97104992A UA66750C2 (en) | 1995-04-11 | 1996-04-11 | Substituted 1-phenylpirazole 3-carboxamides, a method for the preparation thereof and intermediary compounds, pharmaceutical composition having affinity to neurotensin receptors |
Country Status (26)
Country | Link |
---|---|
US (6) | US5723483A (cs) |
EP (2) | EP1097921A1 (cs) |
JP (1) | JP3061644B2 (cs) |
KR (1) | KR100366118B1 (cs) |
CN (1) | CN1072210C (cs) |
AR (1) | AR003940A1 (cs) |
AU (1) | AU709119B2 (cs) |
CA (1) | CA2220827A1 (cs) |
CZ (1) | CZ292255B6 (cs) |
EE (1) | EE9700264A (cs) |
FR (1) | FR2732967B1 (cs) |
HU (1) | HUP9801435A3 (cs) |
IL (1) | IL117860A0 (cs) |
IN (1) | IN185700B (cs) |
IS (1) | IS4582A (cs) |
MY (1) | MY114424A (cs) |
NO (1) | NO310071B1 (cs) |
NZ (1) | NZ307227A (cs) |
PL (1) | PL188077B1 (cs) |
RU (1) | RU2195455C2 (cs) |
SK (1) | SK136797A3 (cs) |
TR (1) | TR199701146T1 (cs) |
TW (1) | TW411332B (cs) |
UA (1) | UA66750C2 (cs) |
WO (1) | WO1996032382A1 (cs) |
ZA (1) | ZA962886B (cs) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2732967B1 (fr) | 1995-04-11 | 1997-07-04 | Sanofi Sa | 1-phenylpyrazole-3-carboxamides substitues, actifs sur la neurotensine, leur preparation, les compositions pharmaceutiques en contenant |
US6506747B1 (en) * | 1998-06-05 | 2003-01-14 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents |
DE10146867A1 (de) * | 2001-09-24 | 2003-04-24 | Bayer Ag | Tetrahydroisochinoline |
AU2003223708A1 (en) * | 2002-04-23 | 2003-11-10 | Axys Pharmaceuticals, Inc. | Novel phenyl derivatives as inducers of apoptosis |
GB0225548D0 (en) * | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Compounds |
FR2847160A1 (fr) * | 2002-11-20 | 2004-05-21 | Oreal | Composition capillaire contenant un compose pyrasol-carboxamide, son utilisation pour stimuler la pousse des cheveux et/ou freiner leur chute |
US7166628B2 (en) | 2002-11-27 | 2007-01-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Cytokine inhibitors |
US7078419B2 (en) | 2003-03-10 | 2006-07-18 | Boehringer Ingelheim Pharmaceuticals, Inc. | Cytokine inhibitors |
US20060079566A1 (en) * | 2003-10-03 | 2006-04-13 | Ching-Shih Chen | PDK-1/Akt signaling inhibitors |
GB0323585D0 (en) * | 2003-10-08 | 2003-11-12 | Glaxo Group Ltd | Compounds |
GB0323584D0 (en) * | 2003-10-08 | 2003-11-12 | Glaxo Group Ltd | Compounds |
US20070060629A1 (en) * | 2003-10-17 | 2007-03-15 | Yasuhiro Imanishi | Large conductance calcium-activated k channel opener |
JP4824576B2 (ja) | 2003-12-03 | 2011-11-30 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | サイトカイン生成のインヒビターとしての1,2,3−トリアゾールアミド誘導体 |
ES2329915T3 (es) * | 2004-02-20 | 2009-12-02 | Astrazeneca Ab | Derivados de 1,5-difenilpirazol 3-sustituidos utiles como moduladores de cb1. |
ATE432273T1 (de) | 2004-03-09 | 2009-06-15 | Boehringer Ingelheim Pharma | 3-ä4-heterocyclyl-1,2,3-triazol-1-ylü-n- arylbenzamide als inhibitoren der cytokinenproduktion für die behandlung von chronischen entzündlichen erkrankungen |
EP1745036A2 (en) | 2004-05-03 | 2007-01-24 | Boehringer Ingelheim Pharmaceuticals Inc. | Cytokine inhibitors |
GB0410121D0 (en) * | 2004-05-06 | 2004-06-09 | Glaxo Group Ltd | Compounds |
US7485657B2 (en) * | 2004-05-12 | 2009-02-03 | Boehringer Ingelheim Pharmaceuticals, Inc. | Anti-cytokine heterocyclic compounds |
US7531560B2 (en) * | 2004-11-10 | 2009-05-12 | Boehringer Ingelheim Pharmaceuticals, Inc. | Anti-cytokine heterocyclic compounds |
EP1831177A1 (en) * | 2004-12-23 | 2007-09-12 | AstraZeneca AB | Therapeutic agents |
GB0514738D0 (en) * | 2005-07-19 | 2005-08-24 | Astrazeneca Ab | Therapeutic agents |
US20100113776A1 (en) * | 2006-12-14 | 2010-05-06 | Taisho Pharmaceutical Co.,Ltd. | Pyrazole derivative |
EP2374003B1 (en) | 2009-01-07 | 2015-03-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the treatment, the prognostic assessment and the detection of breast cancer |
US20120135997A1 (en) | 2009-07-17 | 2012-05-31 | Shionogi & Co., Ltd. | Pharmaceutical composition comprising a lactam or benzenesulfonamide compound |
US20110028624A1 (en) * | 2009-07-30 | 2011-02-03 | Genovique Specialties Holdings Corporation | Polymer Compositions That Include High Solvating Plasticizer And Surfactant |
EP2740726A1 (en) * | 2012-12-07 | 2014-06-11 | 3B Pharmaceuticals GmbH | Neurotensin receptor ligands |
US20170174633A1 (en) * | 2014-03-25 | 2017-06-22 | Research Triangle Institute | Pyrazole compounds selective for neurotensin 2 receptor |
BR112016028119A2 (pt) | 2014-06-06 | 2017-08-22 | Res Triangle Inst | Agonistas receptores de apelina (apj) e usos dos mesmos |
EP2954934A1 (en) | 2014-06-11 | 2015-12-16 | 3B Pharmaceuticals GmbH | Conjugate comprising a neurotensin receptor ligand and use thereof |
EP3154638A1 (en) * | 2014-06-10 | 2017-04-19 | 3B Pharmaceuticals GmbH | Conjugate comprising a neurotensin receptor ligand and use thereof |
EP2954933A1 (en) | 2014-06-10 | 2015-12-16 | 3B Pharmaceuticals GmbH | Conjugate comprising a neurotensin receptor ligand |
EP3386976A1 (en) | 2015-12-09 | 2018-10-17 | Research Triangle Institute, International | Improved apelin receptor (apj) agonists and uses thereof |
EP3279197A1 (en) | 2016-08-03 | 2018-02-07 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Diagnosis, treatment and prevention of neurotensin receptor-related conditions |
GB201815695D0 (en) | 2018-09-26 | 2018-11-07 | Mereo Biopharma 1 Ltd | Synthetic method |
GB201815696D0 (en) * | 2018-09-26 | 2018-11-07 | Mereo Biopharma 1 Ltd | Synthetic method |
US12091454B2 (en) | 2022-12-28 | 2024-09-17 | Development Center For Biotechnology | Humanized anti-human neurotensin receptor 1 antibodies and their uses |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE258017C (cs) * | ||||
DE404647C (de) * | 1922-11-18 | 1924-10-20 | Chemische Ind Ges | Verfahren zur Herstellung von Pyrazolonfarbstoffen |
US3520926A (en) * | 1966-11-14 | 1970-07-21 | Hoffmann La Roche | Methylhydrazinomethyl-substituted benzoic acid amides |
US4105766A (en) * | 1977-08-19 | 1978-08-08 | Sterling Drug Inc. | 4,5-Dihydro-5-oxopyrazolo[1,5-a]quinazoline-3-carboxylic acid derivatives |
FR2665898B1 (fr) * | 1990-08-20 | 1994-03-11 | Sanofi | Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
FR2692575B1 (fr) * | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
FR2711140B1 (fr) * | 1993-10-12 | 1996-01-05 | Sanofi Sa | 1-Naphtylpyrazole-3-carboxamides substitués actifs sur la neurotensine, leur préparation, les compositions pharmaceutiques en contenant. |
FR2732967B1 (fr) | 1995-04-11 | 1997-07-04 | Sanofi Sa | 1-phenylpyrazole-3-carboxamides substitues, actifs sur la neurotensine, leur preparation, les compositions pharmaceutiques en contenant |
-
1995
- 1995-04-11 FR FR9504350A patent/FR2732967B1/fr not_active Expired - Fee Related
-
1996
- 1996-04-09 IL IL11786096A patent/IL117860A0/xx unknown
- 1996-04-10 TW TW085104264A patent/TW411332B/zh not_active IP Right Cessation
- 1996-04-10 US US08/630,761 patent/US5723483A/en not_active Expired - Fee Related
- 1996-04-10 IN IN779DE1996 patent/IN185700B/en unknown
- 1996-04-11 EP EP01102661A patent/EP1097921A1/fr not_active Ceased
- 1996-04-11 EP EP96913568A patent/EP0820444A1/fr not_active Withdrawn
- 1996-04-11 WO PCT/FR1996/000546 patent/WO1996032382A1/fr not_active Application Discontinuation
- 1996-04-11 ZA ZA962886A patent/ZA962886B/xx unknown
- 1996-04-11 EE EE9700264A patent/EE9700264A/xx unknown
- 1996-04-11 JP JP8530771A patent/JP3061644B2/ja not_active Expired - Fee Related
- 1996-04-11 AU AU56516/96A patent/AU709119B2/en not_active Ceased
- 1996-04-11 CN CN96193871A patent/CN1072210C/zh not_active Expired - Fee Related
- 1996-04-11 HU HU9801435A patent/HUP9801435A3/hu unknown
- 1996-04-11 CZ CZ19973232A patent/CZ292255B6/cs not_active IP Right Cessation
- 1996-04-11 MY MYPI96001383A patent/MY114424A/en unknown
- 1996-04-11 PL PL96322723A patent/PL188077B1/pl not_active IP Right Cessation
- 1996-04-11 KR KR1019970707194A patent/KR100366118B1/ko not_active IP Right Cessation
- 1996-04-11 UA UA97104992A patent/UA66750C2/xx unknown
- 1996-04-11 NZ NZ307227A patent/NZ307227A/xx unknown
- 1996-04-11 SK SK1367-97A patent/SK136797A3/sk unknown
- 1996-04-11 AR ARP960102151A patent/AR003940A1/es not_active Application Discontinuation
- 1996-04-11 RU RU97118680/04A patent/RU2195455C2/ru not_active IP Right Cessation
- 1996-04-11 TR TR97/01146T patent/TR199701146T1/xx unknown
- 1996-04-11 CA CA002220827A patent/CA2220827A1/en not_active Abandoned
-
1997
- 1997-10-09 IS IS4582A patent/IS4582A/is unknown
- 1997-10-10 NO NO974702A patent/NO310071B1/no not_active IP Right Cessation
- 1997-11-21 US US08/976,309 patent/US5965579A/en not_active Expired - Fee Related
- 1997-11-24 US US08/977,496 patent/US5939449A/en not_active Expired - Fee Related
- 1997-11-24 US US08/976,714 patent/US5936123A/en not_active Expired - Fee Related
- 1997-11-24 US US08/976,691 patent/US5925661A/en not_active Expired - Fee Related
-
1999
- 1999-08-16 US US09/374,697 patent/US6172239B1/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UA66750C2 (en) | Substituted 1-phenylpirazole 3-carboxamides, a method for the preparation thereof and intermediary compounds, pharmaceutical composition having affinity to neurotensin receptors | |
YU56995A (sh) | Soli derivata indola | |
BG104315A (en) | Prostaglandine agonists and their application for the treatment of osteal diseases | |
MY133647A (en) | Substituted quinoline-2-carboxamides, their preparation and their use as pharmaceuticals, and intermediates | |
UA34428C2 (uk) | Заміщені фенілімідазолідини, спосіб їх одержання, фармацевтична композиція, проміжні сполуки | |
PL311122A1 (en) | Water-solublederivatives of camptotectin, method of obtaining them and their application as anticarcinogenic agents | |
IL112495A0 (en) | Phenylacetic acid derivatives, their preparation and compositions containing them | |
MY122262A (en) | Lh-rh peptide analogues their uses and pharmaceutical compositions containing them | |
BG101110A (en) | Substituted pyrimidine compounds and their application | |
IL114294A0 (en) | Sterol derivatives | |
MX9503529A (es) | Derivados de glicinamida, procedimiento para su preparacion y medicamentos que los contienen. | |
IL117091A0 (en) | Methylphenyloxazolidinone derivatives pharmaceutical compositions containing the same and processes for the preparation thereof | |
MX9804588A (es) | Uso de composiciones que comprenden blanqueador de halogeno para suavidad mejorada a la piel. | |
MY118828A (en) | Substituted amino compounds and their use as substances having an analgesic effect | |
MX9801890A (es) | Nuevos compuestos antagonistas selectivos del receptor nk3 humano, procedimiento para su obtencion y composiciones farmaceuticas que los contienen. | |
AU582235B2 (en) | Quinolylglycinamide derivatives,the process for preparation thereof and their therapeutic application as psychotropic drugs | |
MY120683A (en) | New phenylamidine derivatives, processes for their preparation and their use as pharmaceuticals. | |
MY120550A (en) | Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, processes for preparing them and their use as pharmaceutical compositions. | |
AU623805B2 (en) | New use of anti-progestomimetic compounds | |
BG102707A (en) | New triazolopurinpurines, method for their preparation and appplication as medicamentous forms | |
BG102229A (en) | Endothelium receptor antagonists | |
GR1002576B (el) | Φαρμακευτικες συνθεσεις και μια μεθοδος παρασκευης τους. | |
BR9610175A (pt) | Composto processo de preparação do composto composição farmacêutica e utilização do composto | |
EP1027051A4 (en) | ANTITHROMBOTIC AGENTS | |
TW371661B (en) | Novel intermediates and their use to prepare N,N'-bridged bisindolylmaleimides |