UA66748C2 - Phenyl substituted 4-azasteroids fluroderivatives, methods for the preparation thereof (variants) and pharmaceutical composition based thereon - Google Patents

Phenyl substituted 4-azasteroids fluroderivatives, methods for the preparation thereof (variants) and pharmaceutical composition based thereon

Info

Publication number
UA66748C2
UA66748C2 UA97062805A UA97062805A UA66748C2 UA 66748 C2 UA66748 C2 UA 66748C2 UA 97062805 A UA97062805 A UA 97062805A UA 97062805 A UA97062805 A UA 97062805A UA 66748 C2 UA66748 C2 UA 66748C2
Authority
UA
Ukraine
Prior art keywords
group
fluroderivatives
azasteroids
variants
preparation
Prior art date
Application number
UA97062805A
Other languages
English (en)
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of UA66748C2 publication Critical patent/UA66748C2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UA97062805A 1995-09-14 1996-08-09 Phenyl substituted 4-azasteroids fluroderivatives, methods for the preparation thereof (variants) and pharmaceutical composition based thereon UA66748C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9518858.7A GB9518858D0 (en) 1995-09-14 1995-09-14 Phenylsubstituted 4-azasteroid fluoroderivatives
PCT/EP1996/003518 WO1997010257A1 (en) 1995-09-14 1996-08-09 Phenylsubstituted 4-azasteroid fluoroderivatives

Publications (1)

Publication Number Publication Date
UA66748C2 true UA66748C2 (en) 2004-06-15

Family

ID=10780746

Family Applications (1)

Application Number Title Priority Date Filing Date
UA97062805A UA66748C2 (en) 1995-09-14 1996-08-09 Phenyl substituted 4-azasteroids fluroderivatives, methods for the preparation thereof (variants) and pharmaceutical composition based thereon

Country Status (28)

Country Link
US (2) US5922728A (cs)
EP (1) EP0793671B1 (cs)
JP (1) JPH10509188A (cs)
KR (1) KR100448745B1 (cs)
CN (1) CN1104439C (cs)
AR (1) AR004511A1 (cs)
AT (1) ATE189681T1 (cs)
AU (1) AU715858B2 (cs)
BR (1) BR9606638A (cs)
CA (1) CA2204002A1 (cs)
CZ (1) CZ291450B6 (cs)
DE (1) DE69606623T2 (cs)
DK (1) DK0793671T3 (cs)
EA (1) EA000362B1 (cs)
ES (1) ES2144765T3 (cs)
GB (1) GB9518858D0 (cs)
GR (1) GR3033315T3 (cs)
HU (1) HUP9702038A3 (cs)
IL (1) IL120742A (cs)
MY (1) MY116271A (cs)
NO (1) NO309527B1 (cs)
NZ (1) NZ316060A (cs)
PL (1) PL185196B1 (cs)
PT (1) PT793671E (cs)
TW (1) TW357149B (cs)
UA (1) UA66748C2 (cs)
WO (1) WO1997010257A1 (cs)
ZA (1) ZA967631B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054446A (en) * 1997-12-24 2000-04-25 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US6548491B2 (en) * 1997-12-24 2003-04-15 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
AU2001241779A1 (en) 2000-02-25 2001-09-03 Hollis-Eden Pharmaceuticals, Inc. Method of treatment of prostate cancer
US7402577B2 (en) * 2001-10-03 2008-07-22 Merck & Co., Inc. Androstane 17-beta-carboxamides as androgen receptor modulators
EP1641535A4 (en) * 2003-06-30 2008-05-14 Merck & Co Inc 17-ACETAMIDO-4-AZASTEROID DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS
AU2004255749B2 (en) 2003-06-30 2008-12-18 Merck Sharp & Dohme Corp. 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
JP2007522087A (ja) * 2003-06-30 2007-08-09 メルク　エンド　カムパニー　インコーポレーテッド アンドロゲン受容体モジュレータとしての１７−アセトアミド−４−アザステロイド誘導体
AU2004255200A1 (en) * 2003-06-30 2005-01-20 Merck & Co., Inc. 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
CN103787894B (zh) * 2014-02-08 2015-09-16 济南大学 从甲苯二异氰酸酯制备过程中形成的残渣废料中回收甲苯二胺的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9002922D0 (en) * 1990-02-09 1990-04-04 Erba Carlo Spa 17 beta-substituted-4-aza-5 alpha-androstan-3-one derivatives and process for their preparation
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives
GB9216329D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa 17beta-substituted 4-aza-5alpha-androstan-3-one derivatives
GB9608045D0 (en) * 1996-04-18 1996-06-19 Pharmacia Spa Process for preparing steroids having a carboxamide side-chain
US5686501A (en) * 1996-04-19 1997-11-11 Foamex L.P. Breathable open cell urethane polymers

Also Published As

Publication number Publication date
CZ291450B6 (cs) 2003-03-12
PL185196B1 (pl) 2003-03-31
TW357149B (en) 1999-05-01
CA2204002A1 (en) 1997-03-20
NO972186D0 (no) 1997-05-13
MY116271A (en) 2003-12-31
CN1104439C (zh) 2003-04-02
US5922728A (en) 1999-07-13
EA199700063A1 (ru) 1997-12-30
WO1997010257A1 (en) 1997-03-20
PL320114A1 (en) 1997-09-15
NO972186L (no) 1997-07-02
KR100448745B1 (ko) 2004-12-14
ATE189681T1 (de) 2000-02-15
EA000362B1 (ru) 1999-06-24
AU6820596A (en) 1997-04-01
HUP9702038A2 (hu) 1998-03-30
IL120742A (en) 2002-04-21
EP0793671A1 (en) 1997-09-10
NO309527B1 (no) 2001-02-12
JPH10509188A (ja) 1998-09-08
DE69606623D1 (de) 2000-03-16
ZA967631B (en) 1997-04-16
AU715858B2 (en) 2000-02-10
CN1165520A (zh) 1997-11-19
ES2144765T3 (es) 2000-06-16
EP0793671B1 (en) 2000-02-09
DK0793671T3 (da) 2000-07-17
NZ316060A (en) 1999-08-30
GR3033315T3 (en) 2000-09-29
US6114345A (en) 2000-09-05
HUP9702038A3 (en) 1998-11-30
PT793671E (pt) 2000-07-31
CZ146097A3 (en) 1997-10-15
IL120742A0 (en) 1997-08-14
BR9606638A (pt) 1997-11-11
MX9703464A (es) 1997-07-31
GB9518858D0 (en) 1995-11-15
AR004511A1 (es) 1998-12-16
DE69606623T2 (de) 2000-08-31

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