UA127808C2 - Похідна пладієноліду (варіанти) як засіб, що здійснює цілеспрямований вплив на сплайсосому, для лікування раку - Google Patents

Похідна пладієноліду (варіанти) як засіб, що здійснює цілеспрямований вплив на сплайсосому, для лікування раку Download PDF

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Publication number
UA127808C2
UA127808C2 UAA202007214A UAA202007214A UA127808C2 UA 127808 C2 UA127808 C2 UA 127808C2 UA A202007214 A UAA202007214 A UA A202007214A UA A202007214 A UAA202007214 A UA A202007214A UA 127808 C2 UA127808 C2 UA 127808C2
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UA
Ukraine
Prior art keywords
groups
hydroxy
oxo
dimethyl
oxacyclododec
Prior art date
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UAA202007214A
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English (en)
Ukrainian (uk)
Inventor
Ендрю Кук
Домінік Рейнолдс
Доминик Рейнолдс
Чен Жонг
Райан Браун
Шелбі Еллері
Шелби Эллери
Тіванка Самаракун
Тиванка Самаракун
Ксіанг Ліу
Ксианг ЛИУ
Судіп Праджапаті
Судип ПРАДЖАПАТИ
Меган Шіна
Меган Шина
Джейсон Т. Лове
Джеймс Паласіно
Джеймс Паласино
Original Assignee
ЕйСей РендД МЕНЕДЖМЕНТ КО., ЛТД.
Ейсей Рэндд Менеджмент Ко., Лтд.
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Application filed by ЕйСей РендД МЕНЕДЖМЕНТ КО., ЛТД., Ейсей Рэндд Менеджмент Ко., Лтд. filed Critical ЕйСей РендД МЕНЕДЖМЕНТ КО., ЛТД.
Publication of UA127808C2 publication Critical patent/UA127808C2/uk

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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