UA105479C2 - Спосіб одержання 2-сульфініл-1h-бензоімідазолів - Google Patents

Спосіб одержання 2-сульфініл-1h-бензоімідазолів

Info

Publication number
UA105479C2
UA105479C2 UAA201003696A UAA201003696A UA105479C2 UA 105479 C2 UA105479 C2 UA 105479C2 UA A201003696 A UAA201003696 A UA A201003696A UA A201003696 A UAA201003696 A UA A201003696A UA 105479 C2 UA105479 C2 UA 105479C2
Authority
UA
Ukraine
Prior art keywords
benzimidazoles
preparing
sulfinyl
pyridinylmethylsulfinyl
trifluoroethanol
Prior art date
Application number
UAA201003696A
Other languages
English (en)
Russian (ru)
Inventor
Юрней Іскра
Стоян Ставбер
Йордан Берта Котар
Мілош Рузіц
Янез Смодіш
Рок Зупет
Original Assignee
Крка, Товарна Здравіл, Д.Д., Ново Мєсто
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Крка, Товарна Здравіл, Д.Д., Ново Мєсто filed Critical Крка, Товарна Здравіл, Д.Д., Ново Мєсто
Publication of UA105479C2 publication Critical patent/UA105479C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Даний винахід стосується способу одержання 2-(2-піридинілметилсульфініл)-1Н-бензоімідазолівшляхом окисления тіоефірного попередникау присутності трифторетанолу.
UAA201003696A 2007-08-31 2008-08-29 Спосіб одержання 2-сульфініл-1h-бензоімідазолів UA105479C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07115432A EP2030973A1 (en) 2007-08-31 2007-08-31 Process for preparing 2-sulfinyl-1H-benzimidazoles
PCT/EP2008/061443 WO2009027533A1 (en) 2007-08-31 2008-08-29 Process for preparing 2-sulfinyl-1h-benzimidazoles

Publications (1)

Publication Number Publication Date
UA105479C2 true UA105479C2 (uk) 2014-05-26

Family

ID=39047827

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201003696A UA105479C2 (uk) 2007-08-31 2008-08-29 Спосіб одержання 2-сульфініл-1h-бензоімідазолів

Country Status (4)

Country Link
EP (2) EP2030973A1 (uk)
EA (1) EA018796B1 (uk)
UA (1) UA105479C2 (uk)
WO (1) WO2009027533A1 (uk)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009066309A2 (en) * 2007-07-12 2009-05-28 Cadila Healthcare Limited Process for preparation of omeprazole
EP2413911B1 (en) 2009-03-31 2014-02-19 KRKA, D.D., Novo Mesto Progressive emulsion crystallization
CN103012369B (zh) * 2011-05-23 2014-04-23 中山大学 兰索拉唑n晶型及其制备方法和应用
CN102180866B (zh) * 2011-05-23 2013-03-13 中山大学 兰索拉唑晶型及其制备方法和应用
CN103044399B (zh) * 2011-10-12 2014-08-06 北大方正集团有限公司 一种雷贝拉唑及其钠盐的制备方法
EP3187494A1 (en) 2015-12-30 2017-07-05 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of pantoprazole sodium sesquihydrate
CN106478600B (zh) * 2016-09-27 2019-07-02 苏州天马药业有限公司 一种兰索拉唑的精制方法
CN108084158A (zh) * 2016-11-23 2018-05-29 江苏豪森药业集团有限公司 右兰索拉唑的制备方法
CN108623564B (zh) * 2017-03-17 2022-11-04 江苏豪森药业集团有限公司 一种雷贝拉唑类似物的制备方法
CN113125583B (zh) * 2019-12-30 2022-06-21 成都百裕制药股份有限公司 一种注射用泮托拉唑钠中基因毒性杂质含量的检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100362947B1 (ko) * 1999-09-21 2002-11-30 주식회사 대웅 설폭시드 화합물의 제조방법
IL159854A0 (en) * 2001-07-16 2004-06-20 Janssen Pharmaceutica Nv Improved process for preparing benzimidazole-type compounds
EP1467987A1 (en) * 2002-07-26 2004-10-20 Teva Pharmaceutical Industries Ltd. Preparation of lansoprazole and related compounds
AU2002368496A1 (en) * 2002-12-23 2004-07-14 Chemi Spa Process for the preparation of sulphinyl derivatives by oxidation of the corresponding sulfides

Also Published As

Publication number Publication date
EP2181107A1 (en) 2010-05-05
EA201000379A1 (ru) 2010-08-30
EP2030973A1 (en) 2009-03-04
EA018796B1 (ru) 2013-10-30
WO2009027533A1 (en) 2009-03-05

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