EA201000379A1 - Способ получения 2-сульфинил-1н-бензоимидазолов - Google Patents

Способ получения 2-сульфинил-1н-бензоимидазолов

Info

Publication number
EA201000379A1
EA201000379A1 EA201000379A EA201000379A EA201000379A1 EA 201000379 A1 EA201000379 A1 EA 201000379A1 EA 201000379 A EA201000379 A EA 201000379A EA 201000379 A EA201000379 A EA 201000379A EA 201000379 A1 EA201000379 A1 EA 201000379A1
Authority
EA
Eurasian Patent Office
Prior art keywords
benzoimidazoles
sulfinyl
obtaining
pyridinylmethylsulfinyl
trifluoroethanol
Prior art date
Application number
EA201000379A
Other languages
English (en)
Other versions
EA018796B1 (ru
Inventor
Ернеи Искра
Стоян Ставбер
Берта Котар Ёрдан
Милош Рузиц
Янез Смодис
Рок Зупет
Original Assignee
Крка, Товарна Здравил, Д. Д., Ново Место
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Крка, Товарна Здравил, Д. Д., Ново Место filed Critical Крка, Товарна Здравил, Д. Д., Ново Место
Publication of EA201000379A1 publication Critical patent/EA201000379A1/ru
Publication of EA018796B1 publication Critical patent/EA018796B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Настоящее изобретение относится к способу получения 2-(2-пиридинилметилсульфинил)-1Н-бензоимидазолов путем оксисления тиоэфирного предшественника в присутствии трифторэтанола.
EA201000379A 2007-08-31 2008-08-29 Способ получения 2-(2-пиридинилметилсульфинил)-1н-бензимидазолов EA018796B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07115432A EP2030973A1 (en) 2007-08-31 2007-08-31 Process for preparing 2-sulfinyl-1H-benzimidazoles
PCT/EP2008/061443 WO2009027533A1 (en) 2007-08-31 2008-08-29 Process for preparing 2-sulfinyl-1h-benzimidazoles

Publications (2)

Publication Number Publication Date
EA201000379A1 true EA201000379A1 (ru) 2010-08-30
EA018796B1 EA018796B1 (ru) 2013-10-30

Family

ID=39047827

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201000379A EA018796B1 (ru) 2007-08-31 2008-08-29 Способ получения 2-(2-пиридинилметилсульфинил)-1н-бензимидазолов

Country Status (4)

Country Link
EP (2) EP2030973A1 (ru)
EA (1) EA018796B1 (ru)
UA (1) UA105479C2 (ru)
WO (1) WO2009027533A1 (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009066309A2 (en) * 2007-07-12 2009-05-28 Cadila Healthcare Limited Process for preparation of omeprazole
WO2010112222A1 (en) 2009-03-31 2010-10-07 Krka, D.D., Novo Mesto Progressive emulsion crystallization
CN103012369B (zh) * 2011-05-23 2014-04-23 中山大学 兰索拉唑n晶型及其制备方法和应用
CN102180866B (zh) * 2011-05-23 2013-03-13 中山大学 兰索拉唑晶型及其制备方法和应用
CN103044399B (zh) * 2011-10-12 2014-08-06 北大方正集团有限公司 一种雷贝拉唑及其钠盐的制备方法
EP3187494A1 (en) 2015-12-30 2017-07-05 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of pantoprazole sodium sesquihydrate
CN106478600B (zh) * 2016-09-27 2019-07-02 苏州天马药业有限公司 一种兰索拉唑的精制方法
CN108084158A (zh) * 2016-11-23 2018-05-29 江苏豪森药业集团有限公司 右兰索拉唑的制备方法
CN108623564B (zh) * 2017-03-17 2022-11-04 江苏豪森药业集团有限公司 一种雷贝拉唑类似物的制备方法
CN113125583B (zh) * 2019-12-30 2022-06-21 成都百裕制药股份有限公司 一种注射用泮托拉唑钠中基因毒性杂质含量的检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100362947B1 (ko) * 1999-09-21 2002-11-30 주식회사 대웅 설폭시드 화합물의 제조방법
US6919459B2 (en) * 2001-07-16 2005-07-19 Rudy Laurent Maria Broeckx Process for preparing benzimidazole-type compounds
EP1467987A1 (en) * 2002-07-26 2004-10-20 Teva Pharmaceutical Industries Ltd. Preparation of lansoprazole and related compounds
AU2002368496A1 (en) * 2002-12-23 2004-07-14 Chemi Spa Process for the preparation of sulphinyl derivatives by oxidation of the corresponding sulfides

Also Published As

Publication number Publication date
WO2009027533A1 (en) 2009-03-05
UA105479C2 (ru) 2014-05-26
EA018796B1 (ru) 2013-10-30
EP2181107A1 (en) 2010-05-05
EP2030973A1 (en) 2009-03-04

Similar Documents

Publication Publication Date Title
EA201000379A1 (ru) Способ получения 2-сульфинил-1н-бензоимидазолов
LTC3214083I2 (lt) Kvinolono junginių gamybos būdas
BRPI0916499A2 (pt) método de produção de biomassa
BRPI0812362A2 (pt) Métodos para produção de hidrogênio a partir de borano de am^nia
BRPI0923076A2 (pt) produção de gás de síntese através de oxidação controlada de biomassa.
BRPI0920338A2 (pt) produção de peróxido de hidrogênio.
BR112012005592A2 (pt) geração de sementes oleaginosas produzindo alto poliidroxibutirato.
BRPI0910122A2 (pt) "método de produção de biomassa de levedura"
BRPI0925037A2 (pt) Composição contendo piceatanol e método de produzir a composição contendo piceatanol.
UA111142C2 (uk) Одержання заміщених похідних 2-фторакрилової кислоти
BR112013001245A2 (pt) método de produção de ingenol-3-angelato
BR112012000195A2 (pt) método de produção de componentes compósitos avançados.
EE00864U1 (et) Meetod estsitalopraami tootmiseks
CR20110208A (es) Proceso para la preparación de benzonorbornenos
EA200900944A1 (ru) Новый способ получения кристаллической формы v агомелатина
EA201290801A1 (ru) Способ получения сциллоинозита
MX2010001962A (es) Procedimiento para preparar 4-aminobut-2-enolidos.
MX2014004847A (es) Procedimiento para la preparacion y estabilizacion de composiciones de policarbonato modificadas al impacto usando disoluciones diluidas de compuestos acidos.
CY1114147T1 (el) Μεθοδος για την παραγωγη ενδιαμεσων ενωσεων γεφυρωμενων μονοβακταμων
EA201001401A1 (ru) Улучшенные изомальтитсодержащие таблетки и способ их изготовления
MX2013002395A (es) Procedimiento de preparacion de ditiin-tetracarboximidas.
FR2965279B1 (fr) Procede de production de compose oxygene
BR112012019530A2 (pt) processo para preparar um éter carboxilato
DK2290164T3 (da) Isoleringsmateriale
ITVI20080030A1 (it) Procedimento per la produzione di calce idraulica naturale.

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU