TWM326441U - Biological safety cabinet with air curtain - Google Patents

Description

06. 10. 25 / : ..,,1一mj .丫····W,... M326441 : Eight, new description: ' 【New technology field】 This creation department is about a curtain-type biological safety cabinet. By forming an air curtain at the valve opening, it can effectively achieve the airflow in the cabinet and the outside of the cabinet, and the effect of no backflow in the cabinet is obtained, and the airflow in the cabinet is not dissipated, thereby enhancing the pollutants in the cabinet. ) 3⁄4 leak. [Prior Art] The main axis of the biosafety cabinet (BSC) design is to maintain the sterility of the cell line during cell culture and to avoid interaction between the operator and the cell line. In many microbial tests or microbial-mediated processes, the risk of biological hazards is implied, which in turn affects the health and safety of operators. Therefore, in addition to the protection of cell strains, the development of biosafety cabinets needs to ensure the operation. When using the biosafety cabinet, it is protected from the infection of the reactants in the cabinet. Microbiology laboratories require that contaminants must be isolated from biosafety cabinets. However, there are still cases of biosafety cabinet operators dying from bacterial infections, and such similar events continue to occur, showing that there are many weaknesses in conventional biosafety cabinets. In the actual operation, there is M326441 ua 6: η - the situation of harmful substances, the common problems can be roughly divided into ϋ.·, (1) the design does not reach the most appropriate condition · · such as insufficient pumping capacity, the position of the air insertion slot Improper, improper air supply and air distribution, uneven wind speed distribution at the front opening, and improper design of the opening edge. (2) Failure to operate under the most appropriate conditions: such as harmful substances, excessive release, excessive opening area of the sliding door, and the amount of pumping is not adjusted with the operating conditions. All types of biosafety cabinets are classified as Level 2 according to the applicable biohazard level. The second-level biosafety cabinet is also classified into four types: Al, A2, Bl, and B2 according to the latest revised second-level biosafety cabinet standard NSF / ANSI 49 in the United States.

Clark and Mullan, Rake, Kennedy, and Kruse have made other related biosafety cabinets to eliminate contaminant performance tests, and all of them have the ability to eliminate pollutants in the second-stage biosafety cabinet to resist sudden room pressure changes. The safety cabinet's ability to eliminate pollution needs to be strengthened. The second-grade B2 biosafety cabinet is fully vented at 1〇〇〇/〇 and benefits the % airflow. Before the gas is discharged outside, all gases need to pass through the exhaust high efficiency filter, and the exhaust of the safety cabinet needs to be connected to the exhaust system of the building. The apex system has a high filtration effect of 7 M326441 丨, and the Bu Yue Ri- reg. filter, which is ventilated by a high-efficiency hr filter through a blower, enters the cabinet, and then enters the cabinet. (or other positions) each slot is opened with a large amount of air suction (at least 0 57m3 / s), & forming a negative pressure in the cabinet to pump pollutants away from the cabinet, and the top of the cabinet is not enough gas The part will be naturally ventilated into the cabinet by the sash opening. The contaminants in the cabinet are easily leaked at the opening of the cabinet door, and are affected by the external disturbance airflow and/or the switching action of the cabinet door. The traditional biological safety cabinet has insufficient ability to resist sidestream interference and the operation of the door switch. [New content] The main purpose of this creation is to prevent harmful substances in the biosafety cabinet from escaping to the outside, and the airflow in the cabinet does not communicate with each other. For the purpose of above, this creation is a kind of air curtain type biological ampoule cabinet, including a cabinet, a valve, a blower, an air suction slot, an air extractor, a cross flow fan and a high efficiency filter. (High Efficiency particulate Air (HEpA) FUter). The cabinet body is provided with an accommodating space for removing harmful gases, and the side and the upper part of the cabinet body form an open space; the valve activity is combined with the cabinet body side for controlling the air opening degree, the air enthalpy The upper system has 8 M326441

On the cabinet side, the air blower is used to form a plenum at the valve opening to provide air supply; thereby, the air curtain can effectively achieve the airflow isolation between the cabinet and the outside of the cabinet, so that the safety cabinet personnel/wage rolling Not only does the glue not dissipate, it poses a health hazard to the operation, and the contaminated gas gel outside the cabinet can not enter the cabinet and cause pollution to the product when the biological safety cabinet is operated. [Embodiment] μ No month is shown in "Figure 1 to Figure 3", which is a three-dimensional diagram of the creation, a schematic view of the side of the creation, and a schematic diagram of the equipment and instrument configuration of the creation. As shown in the figure, the creation consists of at least one cabinet 1 1 , one valve 1 2, a blower 1 3 , an air suction slot 1 4 , an air extractor 丄 5 , a cross flow fan 2 0 and a high High Efficiency Particulate Air (HEPA)

Filter ) 1 6 constitutes. Thereby, the airflow in the cabinet and the outside of the cabinet can be effectively insulated and the backflow in the cabinet can be obtained, and the flow of the air in the cabinet is not dissipated, thereby enhancing the leakage of the beta pollutants in the cabinet. The interior of the cabinet of Luihai 1 1 is provided with a space for removing harmful gases, and one side and the top of the cabinet 1 1 form an open space. The valve 12 is movably coupled to one side of the cabinet 1 1 and is provided with a handle 1 2 1 for moving the valve 12 to become a valve opening control. The valve 12 is provided with a cross flow fan 20, which is a two-section sliding door mechanism, which can extend the position of the air blowing port according to the change of the opening degree of the door. In the supply of the gas blown by the valve 12, a row of cross-flow fans (Cr〇SS fans) 20 is provided on the hood to provide a stable blowing air flow, and the cross flow fan controller 2 controls the galvanometer fan 2 〇, After passing the airflow through the upper end of the valve 1 2 to the rectifier section (honeycombs) 1 2 3, the stabilizing zone 1 2 4 dissipates part of the strenuous energy to reach the blown airflow in the open area of the valve 12, mainly A frequency converter a7 a (inverter) controls the air blower 13 and is connected via a winding pipe to an air inlet 1 1 1 ' disposed at the top of the south efficiency Clean air · M326441 Γ§〇Γ5Ι^;:. +year month ug The suction slot 1 4 is set in the cabinet 1 [one: lower edge and is provided with a suction slot 141, the suction slot Sew 1 4 1 is the corresponding valve 1 2 . The air extractor 15 is disposed at the outlet end of the air suction slot 14 for removing harmful gases, and the air extractor 15 is changed by a frequency conversion to 1 7 b and controls the speed of the air extractor i 5 . And the average speed of inhaled wear. In addition, a venturi fl〇w meter 丄8 is arranged between the air extractor 15 and the outlet end of the suction slot 14 for measuring the suction speed, and the venturi is 8 8 A pressure transducer (19) is used in conjunction with the pressure transducer to determine the pressure difference.

The high efficiency filter J 6 is disposed above the cabinet i i to provide a supplement II, and the high efficiency filter i 6 is passed through the blower 13 to provide an average air supply speed. The air curtain type biosafety cabinet is constructed by the above structure. The characteristics of this creation are as follows: The cabinet 1 1 side, and the gas 2 〇 ' and the inverter 1 7 a winding pipe connected to the air inlet 1 1 6 Xuan valve 1 2 system activity combined with the door 1 2 A cross-flow fan is provided to control the blower 13 and is disposed at the top of the 11 M326441 high-efficiency filter 16 via the air inlet 111, and the airflow is supplied through the high efficiency " The valve 1 2 is provided with a cross flow fan 20, which is a two-section sliding door mechanism, which can prolong the position of the air blowing port according to the change of the opening degree of the door. In the supply of the gas blown by the valve 12, 'mainly by a row of horizontal fans on the hood, 20', a stable blowing airflow is provided, and the cross flow fan controller 2 controls the cross flow fan 20 to pass the airflow through the valve. After the upper end of the 1 2 to the rectifier section (honeycombs) 1 2 3, the turbulent energy is dissipated through the stabilization zone 1 2 4 to reach the open area 1 2 5 of the valve 1 2 , and at the same time in the suction slot ^ 4 An air suction slot i 4 i is disposed at the lower edge of the front end of the cabinet 1 , and the suction slot 4 1 corresponds to the valve i 2 , thereby forming a blown air curtain (air'丨at〇 r) (ie air curtain). The flow field is visualized to diagnose the biological safety cabinet flow field, and the air curtain flow field molds under different blowing speeds can be distinguished to effectively control the biological text cabinet flow field, so as to achieve the Keshi private β and transport to the enhanced protective cabinet. The internal pollution leaks, and changes the position of the suction 彳w / drag u hole in order to be close to the effective local pumping action of the cabinet; in addition, ^ ^ ^, J error is set by the cabinet Ί 1 Bu high efficiency According to the device turbulence, in order to meet the physical mechanism of pumping and qi, suitable for 'clean pores; thereby, the air curtain type 12 M326441 rnruiir; ' g ^ /- near to do instant:: 乂 both pumping and qi m The local pumping action of pollution, the biological safety cabinet 1 source _, + 丄 effect barrier pollutants: the second part of the pumping action 'and the formation of air curtains to block harmful gases and _ so that the creation of the waiter has a quick elimination, convenience and =...Source and other effects, increase its practicability, please refer to "Differ 4th ~ 7th C" as shown in the figure below, which is the straight mode of the different blowing ratios

Figure, the creation of this; ^ A with the corpse of the ratio of the slight concave mode of the corpse, the difference between the different blow ratios of the creation of the severe concave mode and the creation of the different blowing ratio of the swing mode Unintentional evolution over time. As shown in the figure, in the discriminating of the flow field mode, the flow field visual diagnosis is used to record the observed flow field type and the matching blowing speed, and use this as the basis of the modal partition. . In the blown-type air curtain mode partition, which is used for the biosafety cabinet, it is mainly divided into four modes, namely, a straight curtain 7 1 , a slightly concave concave curtain. Severely concave curtain 7 3, oscillating curtain 7 4. The conditions for defining these four modes are defined by the different air curtain flow field types, as well as the different air curtain flow field types. The top of the biosafety cabinet is 13 M326441.

3 a 11. Year 29 R High-efficiency filter manufacturing ΤΑ A:: The airflow is generated by the valve i 2, and the suction position is the front suction, and the six θ t jet airflow, as a definition of these different machines. Conditional conditions. f created in the thin ' τ (when, 流, the flow field inside the cabinet 11) slightly concave 模 mode (slightly c〇ncave curtain) 7 2 · go k. Although the popularity of the mouth speed, qi speed and suction When the gas velocity is adjusted to the appropriate ratio of L 彳 1 field, the air curtain blown out by the valve 1 2 will show a slight concave tendency in the cabinet, and when the air flow flows close to the suction end, the suction is pulled down again. (b) Straight curtain 7 1 ·· When the inhalation speed is much smaller than the above, the valve 丄 2 The air curtain flow field that is blown out has no concave shape and presents a relatively straight state, but does not generate backflow in the cabinet; (C) severely concave curtain 7 3 : the suction speed is increased, so that The air curtain airflow moves into the cabinet and presents a serious concave phenomenon, which causes obvious backflow in the cabinet; (d) oscillating curtain 7 4 ··There is a significant backflow inside and outside the cabinet, and it varies with time. It also shows the phenomenon of swinging left and right. In combination with the flow field modes of the above four air curtains, biosafety 14 9a 11· 2 9^:: ;:! Year Month q匕 loss·-丨 'Z^B i It is recommended to use this slight concave 襄' state

M326441 ^ The cabinet is operated on the suction speed 12. However, the change in the suction speed of the air curtain type biosafety cabinet 1 creates many different flow field patterns in the air curtain and the cabinet. These different types of flow fields are easy to confuse and difficult to grasp the key points. Therefore, it is necessary to sort out a systematic flow field mode by multiple experiments and parameter adjustments to clarify the various suction speeds and valves. The air curtain flow field type under opening degree and defines the applicable characteristic area and range. In summary, this creation is a kind of air curtain type biological safety cabinet, which can effectively improve various shortcomings of the conventional use, and it can form an air curtain at the valve opening, which can effectively achieve the airflow isolation inside the cabinet and the cabinet, so that the pollution inside the cabinet The gas glue not only does not dissipate, but also causes the health hazard to the operator, and can cause the pollution of the cabinet to not pollute the product when the biosafety cabinet is operated, thereby causing the creation of the creation. Can be more progressive, more practical, more consistent, the user must 'have met the requirements of the new patent application, 提出 file a patent application according to law. The above-mentioned ones are only preferred for this creation. The scope of this creation cannot be limited by this, and the examples are

M326441 The equivalent equivalent changes and modifications made in the scope of this patent application and the contents of the new manual shall remain within the scope of this new patent. 16 M326441

B

[Simple description of the diagram] Figure 1 is a three-dimensional diagram of the creation. The j 2 diagram is a schematic view of the side of the creation. Figure 3 is a schematic diagram of the equipment and instrument configuration of this creation. Figure 4 is a schematic diagram of the straight mode of the different blowing ratios of this creation. Figure 5 is a schematic diagram of a slightly concave modality at different blowing ratios. Figure 6 is a schematic diagram of the severe concave mode under different blowing ratios. The 7th A ^ 7 C diagram, γ ° , is the same as the different blowing ratio of the swinging mode with time [main components Wei description] air curtain biological safety cabinet 1 cabinet 1 1 air inlet 111 valve 1 2 Handle 1 2 1 Rectifier section 1 2 3 Stabilization zone 1 2 4: 17

··6:B M326441 7 b Open area 1 2 5 blower 1 3 suction slot 1 4 suction slot 1 4 1 air extractor 1 5 high efficiency filter 1 6 frequency converter 1 7 a , 1 venturi 1 8 Pressure converter 1 9 Cross flow fan 2 0 Cross flow fan controller 2 Straight mode 7 1 Slightly concave mode 7 2 Severe concave mode 7 3 Swing mode 7 4 18

Claims (1)

96· 6, Η M326441; IX. Patent application scope: A rolling curtain type biological safety cabinet includes: a cabinet with a cabinet of 4 cabinets with a space for removing harmful gases, and the description: ^ one side of the cabinet limb and The upper part forms an open space; a door, the valve activity is combined with one side of the cabinet for controlling the valve opening degree - the valve is provided with a blow hood; - (High Efficiency Particulate Air _ΡΑ" lher ) The high-efficiency filter is disposed above the cabinet to provide an air supply; a blower is connected to an air inlet disposed at a top end of the high-efficiency filter to provide clean air; a gas trough, the suction trough is disposed at a lower edge of the front end of the cabinet, and is provided with an inhalation slot, wherein the inhalation slot is disposed corresponding to a blower cover of the valve; and an end aspirator, The air extractor is used for removing harmful gases. The air curtain type bio-enclosure cabinet according to the scope of the patent application is provided in the air suction slot, wherein the air system can be a single section, two sections or Multi-section two-in-one production and use And convenience. 19 "Moon 曰" a M326441 I in the month of El $ one - ^ J 3 · According to the application for patent bell HI Chu L - __________________________^ rJyU: Yuesi ^ 围 第 第 第 第 ~ ~~7 ^ — ^, 岍 之 轧 轧 生物 生物 生物 生物 生物 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中 其中The adjustment of the air volume or the outlet air speed can be controlled by the inverter. The air curtain type biosafety cabinet according to claim 1, wherein the valve system can be provided with a handle for moving the valve, Φ to control the valve opening. 6 5 According to the air curtain type biosafety cabinet of claim 1, wherein the pumping system is realized by an air extractor and a pipeline, and the air intake air volume or the air inlet speed can be changed by using a frequency converter. The air curtain type biosafety plant according to claim 1, wherein the high efficiency filter passes through the blower to provide an average air supply speed. 20