JP2008295448A - Air-isolator type biosafety cabinet - Google Patents

Air-isolator type biosafety cabinet Download PDF

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JP2008295448A
JP2008295448A JP2007330290A JP2007330290A JP2008295448A JP 2008295448 A JP2008295448 A JP 2008295448A JP 2007330290 A JP2007330290 A JP 2007330290A JP 2007330290 A JP2007330290 A JP 2007330290A JP 2008295448 A JP2008295448 A JP 2008295448A
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air
cabinet
door
curtain
biological safety
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JP4775595B2 (en
Inventor
Rong-Fung Huang
黄榮芳
Tung-Sheng Shih
石東生
Cheng-Ping Chang
張振平
Chun-Wan Chen
陳春萬
Jen-Shiung Hung
洪振雄
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GYOSEIIN ROKO IINKAI ROKO ANZEN EISEI KENKYUSHO
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GYOSEIIN ROKO IINKAI ROKO ANZEN EISEI KENKYUSHO
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00Enclosures; Chambers
    • B01L1/50Enclosures; Chambers for storing hazardous materials in the laboratory, e.g. cupboards, waste containers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B15/00Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area
    • B08B15/02Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area using chambers or hoods covering the area
    • B08B15/023Fume cabinets or cupboards, e.g. for laboratories
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F3/00Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
    • F24F3/12Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling
    • F24F3/16Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by purification, e.g. by filtering; by sterilisation; by ozonisation
    • F24F3/163Clean air work stations, i.e. selected areas within a space which filtered air is passed
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F9/00Use of air currents for screening, e.g. air curtains

Abstract

<P>PROBLEM TO BE SOLVED: To provide an air-isolator type biosafety cabinet. <P>SOLUTION: The cabinet has a purge port generating air flow from the upper side to the lower side is formed on an air regulating door, a low suction-type suction slit is set at the under side, an air-isolator is formed at an aperture of the air regulating door, by using the low suction type suction slit and the air flow from the upper side to the lower side, thereby the air flow in the cabinet and the air flow outside the cabinet are effectively isolated to strengthen with respect to external interferences, more than for the conventional biosafety cabinets, the staining gas in the safety cabinet is not dispersed so that health of workers is not harmed, and the staining gas outside the cabinet will not enter the cabinet and pollute the products, when the biosafety cabinet is operated. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

本発明は、エアーカーテン式生物学的安全性キャビネットに関し、特に調風戸の開口にエアーカーテンが形成され、有効にキャビネット内とキャビネット外の気流を隔離し、また、キャビネット内に回転流がない効果が得られ、そして、該キャビネット内の気流も発散しなく、更に、キャビネット内の汚染物の漏れを確実に防止できるものに関する。 The present invention relates to an air curtain type biological safety cabinet, and in particular, an air curtain is formed in an opening of a wind-tuning door, and the air flow inside and outside the cabinet is effectively isolated, and there is no rotational flow in the cabinet. And the airflow in the cabinet is not diverged, and further, it is possible to reliably prevent the leakage of contaminants in the cabinet.

生物学的安全性キャビネット(biosafety cabinet、BSC)の研発設計の主な目的は、細胞培養の時、細胞株の無菌化過程を維持して、作業員と細胞株との交互汚染を防止するためである。多くの微生物試験や微生物を媒介とする製程において、生物性危害のリスクが隠れられ、作業員の健康や安全に悪影響を与え、そのため、生物学的安全性キャビネットの発展は、細胞株無菌化の他に、操作者が生物学的安全性キャビネットを使用する時、キャビネット内の反応物によれ感染されることを防止する。 The main objective of the biosafety cabinet (BSC) research design is to maintain the cell line sterilization process during cell culture to prevent alternating contamination of workers and cell lines Because. Many microbial tests and microbial-mediated processes hide the risk of biological hazards and adversely affect the health and safety of workers, so the development of biological safety cabinets has led to cell line sterilization. In addition, when an operator uses a biological safety cabinet, it is prevented from being infected by reactants in the cabinet.

微生物実験室において、汚染物が生物学的安全性キャビネット内に隔離されることを要求するが、生物学的安全性キャビネットの作業員が細菌感染による死ぬ事故が発生し、また、類似する事故が繰り返して発生する現状であり、それにより、従来の生物学的安全性キャビネットは、多い問題点がある。実際の操作において、有害物発散の状況は、おおざっぱに、
(1)設計が最適状況ではない:例えば、ガス抜き量不足やガス抜きスリットの位置が適当ではないこと、エアー補給ガス抜きの配置が不適であること、前あき(front opening)の風速分布が均一ではないこと及び開口辺縁の設計が適当ではないこと等と、
(2)最適ではない状況下で操作する:例えば、有害物の放出量が多すぎることや戸の開度面積が大きすぎること及びガス抜き量を操作状況に応じて調整していないこと等との2種類がある。
Microbiological laboratories require that contaminants be sequestered in biological safety cabinets, but biological safety cabinet workers are killed by bacterial infections and similar accidents occur. The current situation occurs repeatedly, so that the conventional biological safety cabinet has many problems. In actual operation, the status of harmful substance release is roughly
(1) The design is not optimal: for example, the amount of degassing is insufficient or the position of the degassing slit is not appropriate, the arrangement of degassing is not suitable, and the wind speed distribution of the front opening is It is not uniform and the design of the opening edge is not appropriate.
(2) Operate under non-optimal conditions: For example, the amount of harmful substances released is too large, the door opening area is too large, and the amount of venting is not adjusted according to the operating conditions. There are two types.

様々の生物学的安全性キャビネットは、適用される生物危害レベルに従って、3階段に分けられる。その中、第二級の生物学的安全性キャビネットは、米国2002年に訂正された第二級生物学的安全性キャビネット標準NSF/ANSI 49によれば、A1、A2、B1、B2の4種類がある。 The various biological safety cabinets are divided into three steps according to the applied biohazard level. Among them, there are four types of second-grade biological safety cabinets, A1, A2, B1, and B2, according to the second-class biological safety cabinet standard NSF / ANSI 49 corrected in US 2002. There is.

Clark and Mullan、Rake、Kennedy、Kruseにより、生物学的安全性キャビネットが汚染物を排除する性能についてテストを行い、全ての第二級生物学的安全性キャビネットは、汚染物を排除する能力が突然の室内圧力変化に対処できず、そのため、生物学的安全性キャビネットの汚染を排除する能力を強化しなければならない。 Clark and Mullan, Rake, Kennedy, and Kruse have tested the performance of biological safety cabinets to eliminate contaminants, and all secondary biological safety cabinets are suddenly capable of eliminating contaminants. Inability to cope with the indoor pressure changes in the room, therefore, the ability to eliminate contamination of the biological safety cabinet must be enhanced.

第二級B2型の生物学的安全性キャビネットは、100%全排気で、循環気流無しのものである。気体を室外へ排出する前、全ての気体を高効率エアーフィルターを介して排気することが必要であり、また、安全キャビネットの排気を建物の排気系統に連結することが必要である。その上端に、高濾過効果である高効率エアーフィルターが設置され、ブロワーで高効率エアーフィルターを介して、エアーをキャビネット内へ補給し、また、キャビネット内の前後(或いは、他の位置)に、それぞれ凹槽を形成し、排気ファンで大量にガスを抜き(少なくとも、0.57m3/s)、キャビネット内を負圧に形成して、汚染物をキャビネットから排出し、また、キャビネットの上部においてエアーが不足になる場合、サッシ(sash)の開口から自然エアーで、キャビネット内にエアーを補給する。しかしながら、キャビネット内の汚染物は、サッシの開口において、外部の干渉気流及び/或いはサッシの開閉作動による影響により漏れる。そのため、従来の生物学的安全性キャビネットは、側流干渉とサッシの開閉動作に対応する能力が不足である。 The second grade B2 biological safety cabinet is 100% exhausted and has no circulating airflow. Before exhausting the gas out of the room, it is necessary to exhaust all the gas through a high-efficiency air filter and to connect the safety cabinet exhaust to the building exhaust system. At the upper end, a high-efficiency air filter that has a high filtration effect is installed, and air is supplied into the cabinet through the high-efficiency air filter with a blower, and before and after (or other positions) in the cabinet, A concave tank is formed, and a large amount of gas is exhausted with an exhaust fan (at least 0.57 m3 / s), the inside of the cabinet is formed at a negative pressure, and contaminants are discharged from the cabinet. If there is a shortage of air, air is supplied into the cabinet with natural air from the opening of the sash. However, contaminants in the cabinet leak at the opening of the sash due to the influence of external interference airflow and / or the opening and closing operation of the sash. Therefore, the conventional biological safety cabinet lacks the ability to cope with side-flow interference and sash opening and closing operations.

本発明の主な目的は、生物学的安全性キャビネット内の有害物が外部に発散することを防止でき、また、キャビネット内の気流が互いに交流しないエアーカーテン式生物学的安全性キャビネットを提供する。 The main object of the present invention is to provide an air curtain type biological safety cabinet that can prevent harmful substances in the biological safety cabinet from spreading to the outside and that the airflow in the cabinet does not exchange with each other. .

本発明は、上記の目的を達成するため、少なくとも、キャビネットと調風戸、送風機、吸込み槽、ガス抜き機、貫流ファン及び高効率エアーフィルター(High Efficiency Particulate Air(HEPA)Filter)が備えられるエアーカーテン式生物学的安全性キャビネットである。該キャビネットは、内部に有害ガスを排除するための収納空間が設けられ、一側と上方に開放空間が形成され、該調風戸は可動的に該キャビネットの一側に結合され、上に貫流ファンが設置され、該送風機は該キャビネットの上端に設置され、クリーンなエアーを供給する給気口が接続され、該吸込み槽は該キャビネットの先端の下縁に設けられ、また、該調風戸のパージポートに対応する吸込みスリットが設けられ、該ガス抜き機は該吸込み槽の出口端に設けられ、有害ガスを排除し、該高効率エアーフィルターは該キャビネットの上方に設置され、該送風機でエアーを補給し、これにより、調風戸の開口にエアーカーテンが形成され、有効にキャビネット内とキャビネット外の気流を隔離でき、安全キャビネット内の汚染性気体が発散することないため、作業員の健康に危害することがなく、また、キャビネット外の汚染性気体が生物学的安全性キャビネットを操作する時、キャビネット内へ入って製品を汚染することがない。 In order to achieve the above-described object, the present invention provides at least an air curtain including a cabinet, a wind door, a blower, a suction tank, a degasser, a cross-flow fan, and a high-efficiency particulate air (HEPA) filter. Formula biological safety cabinet. The cabinet is provided with a storage space for eliminating harmful gases inside, an open space is formed on one side and above, the air conditioning door is movably coupled to one side of the cabinet, and a cross-flow fan on the top The air blower is installed at the upper end of the cabinet, an air supply port for supplying clean air is connected, the suction tank is provided at the lower edge of the end of the cabinet, and the purge of the air conditioning door A suction slit corresponding to the port is provided, the degasser is provided at the outlet end of the suction tank, eliminates harmful gas, and the high-efficiency air filter is installed above the cabinet. Replenishment, thereby forming an air curtain in the opening of the air-conditioning door, which can effectively isolate the air flow inside and outside the cabinet, and polluting gas inside the safety cabinet Because never, without having to harm the health of workers, also, when the pollution gas outside the cabinet to operate the biological safety cabinet, there is no possibility of contaminating the product it enters into the cabinet.

図1〜図3は、それぞれ、本発明の立体概念図や本発明の側面概念図及び本発明の設備と装置の配置概念図である。図のように、本発明は、少なくとも、キャビネット11と調風戸12、送風機13、吸込み槽14、ガス抜き機15、貫流ファン20及び高効率エアーフィルター(High Efficiency Particulate Air(HEPA)Filter)16から構成される。これにより、有効にキャビネット内とキャビネット外の気流を隔離でき、また、キャビネット内において回転流がなく、そして、該キャビネット内の気流も発散しなくて、更にキャビネット内の汚染物の漏れを確実に防止できる。 1 to 3 are a three-dimensional conceptual diagram of the present invention, a side conceptual diagram of the present invention, and an arrangement conceptual diagram of the facility and apparatus of the present invention, respectively. As shown in the figure, the present invention includes at least a cabinet 11 and a conditioned door 12, a blower 13, a suction tank 14, a degasser 15, a cross-flow fan 20, and a high-efficiency particulate air (HEPA) filter 16. Composed. This effectively isolates the airflow inside and outside the cabinet, and there is no rotating flow inside the cabinet, and the airflow inside the cabinet is not diverged, further ensuring the leakage of contaminants inside the cabinet. Can be prevented.

該キャビネット11は、内部に、有害ガスを排除するための収納空間が設けられ、また、その一側と上方に開放空間が形成される。 The cabinet 11 is provided with a storage space for eliminating harmful gases, and an open space is formed on one side and above.

該調風戸12は、可動的に該キャビネット11の一側に結合され、また、該調風戸12を移動するための取っ手121が設けられ、これにより、調風戸の開度を制御できる。該調風戸12は、上に貫流ファン20が設けられ、二段式の引き戸機構であり、エアー吹き口の位置がサッシの開度に応じて変化できる。該調風戸12から吹出された気体は、主として、パージポート上に安定な気流を提供するための一列の貫流ファン(cross flow fans)20が設けられ、貫流ファン20が貫流ファン制御器2によって制御され、気流が該調風戸12の上端を介して、整流段(honeycombs)123に到達した後、更に、安定区124により一部の乱流エネルギーを打ち消しながら、該調風戸12の開口区125に到達する。 The air-conditioning door 12 is movably coupled to one side of the cabinet 11, and a handle 121 for moving the air-conditioning door 12 is provided, whereby the opening degree of the air-conditioning door can be controlled. The air-conditioning door 12 is provided with a cross-flow fan 20 and is a two-stage sliding door mechanism, and the position of the air outlet can be changed according to the opening degree of the sash. The gas blown out from the air conditioning door 12 is mainly provided with a row of cross-flow fans 20 for providing a stable air flow on the purge port, and the cross-flow fan 20 is controlled by the cross-flow fan controller 2. After the airflow reaches the rectifying stage (honeycombs) 123 via the upper end of the air conditioning door 12, the airflow further enters the opening area 125 of the air conditioning door 12 while canceling a part of the turbulent energy by the stable area 124. To reach.

下吹き気流は、主として、インバータ17a(inverter)で送風機13を制御し、可撓性パイプを介して、該高効率エアーフィルター16の上端に設置された給気口111に接続され、クリーンなエアーを供給し、該吸込み槽14は、該キャビネット11の先端の下縁に設置され、また、該調風戸12に対応する吸込みスリット141が設けられる。 The lower blowing airflow is mainly controlled by the inverter 17a (inverter) and the blower 13 is connected to the air supply port 111 provided at the upper end of the high-efficiency air filter 16 through a flexible pipe. The suction tank 14 is installed at the lower edge of the tip of the cabinet 11, and a suction slit 141 corresponding to the air conditioning door 12 is provided.

該ガス抜き機15は、該吸込み槽14の出口端に設置され、有害ガスを排除し、インバータ17bでガス抜き機15の回転数や吸込み断面平均速度を制御する。 The degasser 15 is installed at the outlet end of the suction tank 14 to remove harmful gases, and the inverter 17b controls the rotation speed of the degasser 15 and the suction section average speed.

また、該ガス抜き機15と吸込み槽14の出口端との間に吸込み速度を測定するベンチュリ管(venturi flow meter)18が設置され、また、該ベンチュリ管18に合わせて、圧差を測定する圧力変換器19(pressure transducer)が設置される。 In addition, a venturi pipe 18 for measuring the suction speed is installed between the venting machine 15 and the outlet end of the suction tank 14, and the pressure for measuring the pressure difference is adjusted to the venturi pipe 18. A converter 19 (pressure transducer) is installed.

該高効率エアーフィルター16は、該キャビネット11の上方に設置され、エアーを補給し、また、該送風機13を通すことにより均一的な速度でエアー補給を行う。上記の構造により、新規のエアーカーテン式生物学的安全性キャビネット1が構成される。 The high-efficiency air filter 16 is installed above the cabinet 11 to replenish air and to replenish air at a uniform speed by passing the blower 13. With the above structure, a novel air curtain biological safety cabinet 1 is configured.

本発明の特徴として、該調風戸12が可動的に該キャビネット11の一側に結合され、該調風戸12の上に貫流ファン20が設けられ、また、インバータ17aで送風機13を制御し、また、可撓性パイプを介して給気口111に接続され、給気口111が高効率エアーフィルター16の上端に設置され、気流を高効率エアーフィルター16としてからエアーを補給する。調風戸12は、上に貫流ファン20が設けられ、二段式の引き戸機構であり、エアー吹き口の位置がサッシの開度に応じて変化できる。該調風戸12から吹出された気体は、主として、パージポート上に、安定な気流を提供するための一列の貫流ファン(cross flow fans)20が設けられ、貫流ファン20が貫流ファン制御器2によって制御され、気流が該調風戸12の上端を介して、整流段(honeycombs)123に到達した後、更に、安定区124により、一部の乱流エネルギーを打ち消しながら、該調風戸12の開口区125に到達し、また、該吸込み槽14の該キャビネット11の先端の下縁に、該調風戸12に対応する吸込みスリット141が設けられ、これにより、プッシュプル式(push−pull)のエアーカーテン(air−isolator)が形成される。流れ視覚化により生物学的安全性キャビネットの流れの場を検知して、異なる吹き吸い速度下のエアーカーテンの流れの場モードを認識でき、更に、有効に生物学的安全性キャビネットの流れの場を制御して、キャビネット内の汚染物の漏れを確実に防止でき、また、ガス抜きの位置を変化してキャビネット内の汚染源に接近し、有効に局部のガス抜きを行い、また、該キャビネット11の上方に設置された高効率エアーフィルター16で適当なクリーンな気流を供給し、ガス抜きとエアー補給の物理メカニズムを利用でき、これにより、エアーカーテン式生物学的安全性キャビネット1はガス抜きとエアー補給の機能を両立でき、また、汚染源の近くで、即時に有効に局部のガス抜きを行え、また、エアーカーテンを形成して、有効に汚染物の漏れを防止でき、そのため、本発明は快速的に有害ガスを排除や隔離でき、また、エネルギーを節約できる効果が得られ、その実用性や便利性及び安全性が向上される。 As a feature of the present invention, the air-conditioning door 12 is movably coupled to one side of the cabinet 11, a cross-flow fan 20 is provided on the air-conditioning door 12, the blower 13 is controlled by an inverter 17a, and The air supply port 111 is connected to the air supply port 111 via a flexible pipe, and the air supply port 111 is installed at the upper end of the high-efficiency air filter 16. The air conditioning door 12 is provided with a cross-flow fan 20 on the top, and is a two-stage sliding door mechanism, and the position of the air blowing port can be changed according to the opening degree of the sash. The gas blown out from the air conditioning door 12 is mainly provided with a row of cross-flow fans 20 for providing a stable air flow on the purge port, and the cross-flow fan 20 is provided by the cross-flow fan controller 2. After the controlled airflow reaches the rectifying stage (honeycombs) 123 via the upper end of the air conditioning door 12, the stable airspace 124 cancels a part of the turbulent energy and further opens the airflow opening of the air conditioning door 12. 125, and a suction slit 141 corresponding to the air-conditioning door 12 is provided at the lower edge of the tip of the cabinet 11 of the suction tub 14, so that a push-pull air curtain is provided. (Air-isolator) is formed. Flow visualization can detect the flow field of the biological safety cabinet to recognize the air curtain flow field mode under different blowing speeds, and more effectively the flow field of the biological safety cabinet. Can be reliably prevented from leaking contaminants in the cabinet, and the degassing position can be changed to approach the contamination source in the cabinet to effectively degas the local area. A high-efficiency air filter 16 installed above the air can supply an appropriate clean air flow, and the physical mechanism of degassing and air supply can be used. As a result, the air curtain biological safety cabinet 1 Air replenishment function can be achieved at the same time, and local degassing can be performed immediately and effectively near the pollution source, and an air curtain can be formed to effectively contaminate the area. Of prevent leakage, therefore, the present invention can eliminate or isolate the fast harmful gases, also an effect of saving energy can be obtained, the practicability and convenience and safety are improved.

図4〜図7Cは、それぞれ本発明の異なる吹き吸い比のストレートカーテンの概念図や本発明の異なる吹き吸い比の僅か内凹カーテンの概念図、本発明の異なる吹き吸い比の大きく内凹カーテンの概念図及び本発明の異なる吹き吸い比の搖動カーテンの時効変遷の概念図である。図のように、流れの場モードの判別について、流れ視覚化により検知した流れの場形態とそれに対応する吹き吸い速度を記録して、それを、カーテン区分の基準とする。プッシュプル式エアーカーテンモード区分を生物学的安全性キャビネットに適用する場合、主として、4種類のモードに区分され、それぞれは、ストレートカーテン(straight curtain)71や僅か内凹カーテン(slightly concave curtain)72、大きく内凹カーテン(severely concave curtain)73及び搖動カーテン(oscillating curtain)74である。これらの4種類のカーテンを定義する条件は、異なる吹き吸い速度とエアー補給速度による異なるエアーカーテンの流れの場形態の他に、生物学的安全性キャビネットの上部において、高効率エアーフィルターにより下吹き気流を創出することと吸込み位置が前下吸うこと、調風戸12により噴出気流を創出することを、これらの異なる流れの場のモードの付属条件として定義する。 4 to 7C are conceptual diagrams of straight curtains with different blowing ratios according to the present invention, conceptual diagrams of slightly indented curtains with different blowing ratios according to the present invention, and large indented curtains with different blowing ratios according to the present invention. It is a conceptual diagram of aging transition of the peristaltic curtain of a different blowing ratio of the present invention and the present invention. As shown in the figure, for the discrimination of the flow field mode, the flow field form detected by flow visualization and the blowing speed corresponding thereto are recorded, and this is used as the criterion of the curtain section. When the push-pull type air curtain mode division is applied to the biological safety cabinet, it is mainly divided into four kinds of modes, each of which is a straight curtain 71 and a slightly concave curtain 72. And a large concave concave curtain 73 and an oscillating curtain 74. In addition to the different air curtain flow field configurations with different blowing speeds and air replenishment speeds, the conditions defining these four types of curtains are the bottom blowing by the high efficiency air filter at the top of the biological safety cabinet. Creating an air flow, sucking the front and lower suction positions, and creating an ejected air flow by the conditioned door 12 are defined as ancillary conditions for these different flow field modes.

使用する時、該キャビネット11の内部の流れの場は、
(a)僅か内凹カーテン(slightly concave curtain)72:エアー吹き速度やエアー補給速度及び吸込み速度を適当な比例に調整する時、調風戸12から吹出されたエアーカーテンは、キャビネット内へ向かって僅かに内凹するようになり、気流が吸込み端に近付く時、下吸いの吸力によりキャビネット内へもキャビネット外へもならず、
(b)ストレートカーテン(straight curtain)71:吸込み速度が上記より比較的に小さい時、吸込みの力が不足であるため、調風戸12が吹出したエアーカーテンの流れの場は内凹しなく、比較的にストレートの状態になり、キャビネット内に回転流を生成せず、
(c)大きく内凹カーテン(severely concave curtain)73:吸込み速度が大きくすることにより、エアーカーテンの気流がキャビネット内へ移動し、また、大きく内凹になり、キャビネット内において回転流が生成され、
(d)搖動カーテン(oscillating curtain)74:キャビネット内とキャビネット外において回転流が生成され、また、時間に従って、左右へ搖動する現象が起こる。
When used, the flow field inside the cabinet 11 is
(A) Slightly concave curtain 72: When adjusting the air blowing speed, the air replenishing speed, and the suction speed in an appropriate proportion, the air curtain blown out from the air-conditioning door 12 is slightly toward the inside of the cabinet. When the airflow approaches the suction end, the suction force of the lower suction does not move into the cabinet or out of the cabinet.
(B) Straight curtain 71: Since the suction force is insufficient when the suction speed is relatively smaller than the above, the flow field of the air curtain blown out by the air conditioning door 12 is not indented. It becomes a straight state and does not generate a rotating flow in the cabinet,
(C) Largely concave curtain 73: By increasing the suction speed, the airflow of the air curtain moves into the cabinet, and becomes large indented, and a rotating flow is generated in the cabinet.
(D) Oscillating curtain 74: A rotating flow is generated inside and outside the cabinet, and a phenomenon of swinging to the left and right occurs with time.

以上の4種類のエアーカーテンの流れの場モードから、生物学的安全性キャビネットは吹き吸い速度を操作することを前提とする場合、僅か内凹カーテン72が好ましい。 From the above four types of air curtain flow field modes, a slightly indented curtain 72 is preferred when the biological safety cabinet is premised on manipulating the blowing speed.

ところが、エアーカーテン式生物学的安全性キャビネット1の吹き吸い速度を変化すると、エアーカーテンとキャビネット内において、数多い異なる流れの場形態が形成される。これらの異なる形態の流れの場は把握し難いため、多数の実験とパラメータにより、システム的な流れの場モードを整えることにより、各種類の吹き吸い速度と調風戸の開度下のエアーカーテンの流れの場形態を確定でき、また、適用できる特性領域と範囲が決められる。 However, when the blowing speed of the air curtain biological safety cabinet 1 is changed, many different flow field forms are formed in the air curtain and the cabinet. Since these different forms of flow field are difficult to grasp, by adjusting the system flow field mode through a number of experiments and parameters, various types of blowing speeds and air curtains under the opening of the air conditioning door The flow field configuration can be determined, and the applicable characteristic region and range can be determined.

以上のように、本発明は、エアーカーテン式生物学的安全性キャビネットであり、有効に従来の諸欠点を改善でき、調風戸の開口において、エアーカーテンを形成することにより、有効にキャビネット内とキャビネット外の気流を隔離でき、これにより、安全キャビネット内の汚染性気体が発散することないため、作業員の健康に危害することがなく、また、キャビネット外の汚染性気体が生物学的安全性キャビネットを操作する時、キャビネット内へ入って製品を汚染することがないから、本発明はより進歩的かつより実用的で、法に従って特許請求を出願する。 As described above, the present invention is an air curtain biological safety cabinet, which can effectively improve the conventional drawbacks. By forming an air curtain at the opening of the air conditioning door, Airflow outside the cabinet can be isolated, so that no polluting gas in the safety cabinet is released, so there is no danger to the health of workers and the outside of the cabinet is biologically safe. Since the cabinet does not enter the cabinet and contaminate the product when operating the cabinet, the present invention is more progressive and more practical, and claims are filed according to law.

以上は、ただ、本発明のより良い実施例であり、本発明はそれによって制限されることが無く、本発明に係わる特許請求の範囲や明細書の内容に基づいて行った等価の変更や訂正は、全てが本発明の特許請求の範囲内に含まれる。 The above are merely preferred embodiments of the present invention, and the present invention is not limited thereby. Equivalent changes and corrections made based on the scope of claims and the description of the present invention. Are all within the scope of the claims of the present invention.

本発明の立体概念図Three-dimensional conceptual diagram of the present invention 本発明の側面概念図Side conceptual diagram of the present invention 本発明の設備と装置の配置概念図Arrangement conceptual diagram of equipment and apparatus of the present invention 本発明の異なる吹き吸い比のストレートカーテンの概念図Conceptual diagram of straight curtains with different blowing ratios of the present invention 本発明の異なる吹き吸い比の僅か内凹カーテンの概念図Conceptual diagram of slightly indented curtain with different blowing ratio of the present invention 本発明の異なる吹き吸い比の大きく内凹カーテンの概念図Conceptual diagram of a greatly indented curtain with different blowing ratios of the present invention 本発明の異なる吹き吸い比の搖動カーテンの時効変遷の概念図Conceptual diagram of aging transition of peristaltic curtain with different blowing ratio of the present invention 本発明の異なる吹き吸い比の搖動カーテンの時効変遷の概念図Conceptual diagram of aging transition of peristaltic curtain with different blowing ratio of the present invention 本発明の異なる吹き吸い比の搖動カーテンの時効変遷の概念図Conceptual diagram of aging transition of peristaltic curtain with different blowing ratio of the present invention

符号の説明Explanation of symbols

1 エアーカーテン式生物学的安全性キャビネット
11 キャビネット
111 給気口
12 調風戸
121 取っ手
123 整流段
124 安定区
125 開口区
13 送風機
14 吸込み槽
141 吸込みスリット
15 ガス抜き機
16 高効率エアーフィルター
17a インバータ
17b インバータ
18 ベンチュリ管
19 圧力変換器
20 貫流ファン
2 貫流ファン制御器
71 ストレートカーテン
72 僅か内凹カーテン
73 大きく内凹カーテン
74 搖動カーテン
DESCRIPTION OF SYMBOLS 1 Air curtain type biological safety cabinet 11 Cabinet 111 Air inlet 12 Conditioning door 121 Handle 123 Rectification stage 124 Stable section 125 Open section 13 Blower 14 Suction tank 141 Suction slit 15 Degasser 16 High-efficiency air filter 17a Inverter 17b Inverter 18 Venturi tube 19 Pressure transducer 20 Cross-flow fan 2 Cross-flow fan controller 71 Straight curtain 72 Slightly indented curtain 73 Largely indented curtain 74 Peristaltic curtain

Claims (6)

内部に、有害ガスを排除するための収納空間が設けられ、一側と上方に、開放空間が形成されるキャビネットと、
可動的に該キャビネットの一側に結合され、上にパージポートが設けられる調風戸と、
該キャビネットの上方に設置され、エアーを補給する高効率エアーフィルターと、
該高効率エアーフィルターの上端に設置された給気口に接続され、クリーンなエアーを供給する送風機と、
該キャビネットの先端の下縁に設けられ、また調風戸のパージポートに対応する吸込みスリットが設けられる吸込み槽と、
該吸込み槽の出口端に設けられ、有害ガスを排除するガス抜き機が含有されることを特徴とする、エアーカーテン式生物学的安全性キャビネット。
A cabinet in which a storage space for eliminating harmful gas is provided inside, and an open space is formed on one side and above,
A conditioned door movably coupled to one side of the cabinet and provided with a purge port thereon;
A high-efficiency air filter installed above the cabinet and replenishing air;
A blower connected to an air supply port installed at the upper end of the high-efficiency air filter and supplying clean air;
A suction tank provided at the lower edge of the front end of the cabinet and provided with a suction slit corresponding to the purge port of the air conditioning door;
An air curtain type biological safety cabinet, characterized in that it comprises a degasser provided at the outlet end of the suction tank to eliminate harmful gases.
該調風戸は、作製と使用及び便利性に応じて、一段や二段或いは多段式であることを特徴とする、請求項1に記載のエアーカーテン式生物学的安全性キャビネット。 The air curtain biological safety cabinet according to claim 1, wherein the air conditioning door is one-stage, two-stage, or multistage depending on production, use, and convenience. 該調風戸は、気体を吹出す方式が、主として、直接に横方向に調風戸の上方の入口に設置された送風機により供給され、吹出し風量や吹出し口風速は、可インバータによって制御されて調整されることを特徴とする、請求項1に記載のエアーカーテン式生物学的安全性キャビネット。 The air-conditioning door is a method of blowing out gas mainly supplied by a blower installed directly in the upper entrance of the air-conditioning door in the lateral direction, and the blowout air volume and the air velocity at the air outlet are controlled and adjusted by a controllable inverter. The air curtain biological safety cabinet according to claim 1, wherein: 該調風戸は、調風戸を移動して、調風戸の開度を制御する取っ手が設けられることを特徴とする、請求項1に記載のエアーカーテン式生物学的安全性キャビネット。 The air curtain type biological safety cabinet according to claim 1, wherein the air conditioner door is provided with a handle for moving the air conditioner door to control the opening degree of the air conditioner door. ガス抜きは、ガス抜き機を利用しながら、配線に合わせて行われ、吸込み風量や吸入口風速は、インバータにより調整されることを特徴とする、請求項1に記載のエアーカーテン式生物学的安全性キャビネット。 The air curtain biological system according to claim 1, wherein the degassing is performed according to wiring while using a degassing machine, and the suction air volume and the inlet wind speed are adjusted by an inverter. Safety cabinet. 該高効率エアーフィルターは、該送風機を利用して、均一的な速度でエアー補給を行うことを特徴とする請求項1に記載のエアーカーテン式生物学的安全性キャビネット。 The air curtain biological safety cabinet according to claim 1, wherein the high-efficiency air filter supplies air at a uniform speed using the blower.
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