TWI869334B - 一種ｌａｇ-３抗體醫藥組成物及其用途 - Google Patents
一種ｌａｇ-３抗體醫藥組成物及其用途 Download PDFInfo
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- TWI869334B TWI869334B TW107146459A TW107146459A TWI869334B TW I869334 B TWI869334 B TW I869334B TW 107146459 A TW107146459 A TW 107146459A TW 107146459 A TW107146459 A TW 107146459A TW I869334 B TWI869334 B TW I869334B
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| CN102176921A (zh) * | 2008-08-11 | 2011-09-07 | 梅达雷克斯股份有限公司 | 结合淋巴细胞活化基因3(lag-3)之人类抗体及其用途 |
| WO2016028672A1 (en) * | 2014-08-19 | 2016-02-25 | Merck Sharp & Dohme Corp. | Anti-lag3 antibodies and antigen-binding fragments |
| WO2017037203A1 (en) * | 2015-09-02 | 2017-03-09 | Immutep S.A.S. | Anti-LAG-3 Antibodies |
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| CN1110557C (zh) * | 1994-05-06 | 2003-06-04 | 古斯达威罗斯研究所 | Lag－3蛋白的可溶性多肽组分;生产方法、治疗组合物、抗独特型抗体 |
| US6267958B1 (en) * | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US6171586B1 (en) * | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| ES2439580T5 (en) | 2003-02-28 | 2025-01-23 | Univ Johns Hopkins | T cell regulation |
| EP1987839A1 (en) | 2007-04-30 | 2008-11-05 | I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale | Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease |
| UY34887A (es) | 2012-07-02 | 2013-12-31 | Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware | Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos |
| HUE049957T2 (hu) | 2013-03-15 | 2020-11-30 | Glaxosmithkline Ip Dev Ltd | Lag-3 elleni kötõfehérjék |
| KR20160070095A (ko) * | 2013-11-05 | 2016-06-17 | 버베리안 노딕 에이/에스 | 종양 항원을 발현하는 폭스바이러스 및 면역 관문 저해제의 길항제 및/또는 효현제를 구비하는 암을 치료하기 위한 복합제 치료제 |
| JP6772062B2 (ja) * | 2013-12-02 | 2020-10-21 | フィオ ファーマシューティカルズ コーポレーションＰｈｉｏ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｃｏｒｐ． | 癌の免疫療法 |
| LT3116909T (lt) | 2014-03-14 | 2020-02-10 | Novartis Ag | Antikūno molekulės prieš lag-3 ir jų panaudojimas |
| WO2015198312A1 (en) * | 2014-06-24 | 2015-12-30 | Ccam Therapeutics Ltd. | Compositions comprising antibodies to ceacam-1 and lag-3 for cancer therapy |
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| IL262892B2 (en) * | 2016-05-18 | 2024-04-01 | Boehringer Ingelheim Int | Anti pd-1 and anti-lag3 antibodies for cancer treatment |
| TWI757304B (zh) * | 2016-06-23 | 2022-03-11 | 大陸商江蘇恆瑞醫藥股份有限公司 | Lag-3抗體、其抗原結合片段及其醫藥用途 |
| CA3060581A1 (en) | 2017-05-02 | 2018-11-08 | Merck Sharp & Dohme Corp. | Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies |
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- 2018-12-21 BR BR112020011664-5A patent/BR112020011664A2/pt not_active IP Right Cessation
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| CN102176921A (zh) * | 2008-08-11 | 2011-09-07 | 梅达雷克斯股份有限公司 | 结合淋巴细胞活化基因3(lag-3)之人类抗体及其用途 |
| WO2016028672A1 (en) * | 2014-08-19 | 2016-02-25 | Merck Sharp & Dohme Corp. | Anti-lag3 antibodies and antigen-binding fragments |
| WO2017037203A1 (en) * | 2015-09-02 | 2017-03-09 | Immutep S.A.S. | Anti-LAG-3 Antibodies |
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| KR20200104314A (ko) | 2020-09-03 |
| RU2771384C2 (ru) | 2022-05-04 |
| RU2020118313A (ru) | 2022-01-24 |
| JP2021506922A (ja) | 2021-02-22 |
| BR112020011664A2 (pt) | 2020-11-17 |
| CN111356476A (zh) | 2020-06-30 |
| RU2020118313A3 (enExample) | 2022-01-24 |
| WO2019120269A1 (zh) | 2019-06-27 |
| CA3085656A1 (en) | 2019-06-27 |
| AU2018391217A1 (en) | 2020-07-09 |
| EP3714901A4 (en) | 2022-03-02 |
| TW201927337A (zh) | 2019-07-16 |
| CN111356476B (zh) | 2023-03-10 |
| US20220031842A1 (en) | 2022-02-03 |
| EP3714901A1 (en) | 2020-09-30 |
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