TWI866056B - 改善自動聚焦功能的方法以及自動聚焦系統 - Google Patents

改善自動聚焦功能的方法以及自動聚焦系統 Download PDF

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Publication number
TWI866056B
TWI866056B TW112104260A TW112104260A TWI866056B TW I866056 B TWI866056 B TW I866056B TW 112104260 A TW112104260 A TW 112104260A TW 112104260 A TW112104260 A TW 112104260A TW I866056 B TWI866056 B TW I866056B
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TW
Taiwan
Prior art keywords
light
implementations
optical system
autofocus
autofocus light
Prior art date
Application number
TW112104260A
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English (en)
Chinese (zh)
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TW202331329A (zh
Inventor
賽門 皮恩斯
丹尼羅 寇迪羅
文森 謝
克里斯達 豐西里
約翰 歐軒尼斯
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美商伊路米納有限公司
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Publication of TW202331329A publication Critical patent/TW202331329A/zh
Application granted granted Critical
Publication of TWI866056B publication Critical patent/TWI866056B/zh

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Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/245—Devices for focusing using auxiliary sources, detectors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/42—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect
    • G02B27/4233—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect having a diffractive element [DOE] contributing to a non-imaging application
    • G02B27/425—Diffraction optics, i.e. systems including a diffractive element being designed for providing a diffractive effect having a diffractive element [DOE] contributing to a non-imaging application in illumination systems
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/04—Prisms
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/02—Mountings, adjusting means, or light-tight connections, for optical elements for lenses
    • G02B7/04—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification
    • G02B7/09—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification adapted for automatic focusing or varying magnification
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/28—Systems for automatic generation of focusing signals
    • G02B7/30—Systems for automatic generation of focusing signals using parallactic triangle with a base line
    • G02B7/32—Systems for automatic generation of focusing signals using parallactic triangle with a base line using active means, e.g. light emitter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G01N2021/058—Flat flow cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6482—Sample cells, cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Focus Adjustment (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
TW112104260A 2019-12-31 2020-12-24 改善自動聚焦功能的方法以及自動聚焦系統 TWI866056B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962956083P 2019-12-31 2019-12-31
US62/956,083 2019-12-31
US202062959681P 2020-01-10 2020-01-10
US62/959,681 2020-01-10

Publications (2)

Publication Number Publication Date
TW202331329A TW202331329A (zh) 2023-08-01
TWI866056B true TWI866056B (zh) 2024-12-11

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TW112104260A TWI866056B (zh) 2019-12-31 2020-12-24 改善自動聚焦功能的方法以及自動聚焦系統
TW109146010A TWI794708B (zh) 2019-12-31 2020-12-24 改善自動聚焦功能的方法以及自動聚焦系統

Family Applications After (1)

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Country Status (12)

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US (3) US11815458B2 (https=)
EP (2) EP3990891B1 (https=)
JP (1) JP7716994B2 (https=)
KR (1) KR20220118301A (https=)
CN (4) CN217561823U (https=)
AU (1) AU2020418180A1 (https=)
CA (1) CA3144819A1 (https=)
IL (1) IL289312B2 (https=)
MX (1) MX2021016073A (https=)
SA (1) SA521431290B1 (https=)
TW (2) TWI866056B (https=)
WO (1) WO2021138633A1 (https=)

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Also Published As

Publication number Publication date
CN113064266A (zh) 2021-07-02
US11815458B2 (en) 2023-11-14
EP3990891C0 (en) 2025-12-03
IL289312B1 (en) 2024-11-01
EP4682612A2 (en) 2026-01-21
TW202127083A (zh) 2021-07-16
EP3990891B1 (en) 2025-12-03
IL289312A (en) 2022-02-01
BR112021026660A2 (pt) 2022-07-12
CN215953954U (zh) 2022-03-04
JP7716994B2 (ja) 2025-08-01
TW202331329A (zh) 2023-08-01
EP3990891A1 (en) 2022-05-04
EP3990891A4 (en) 2023-07-26
US20210199587A1 (en) 2021-07-01
EP4682612A3 (en) 2026-04-15
KR20220118301A (ko) 2022-08-25
CN217561823U (zh) 2022-10-11
JP2023510438A (ja) 2023-03-14
CN113064266B (zh) 2025-02-25
CA3144819A1 (en) 2021-07-08
SA521431290B1 (ar) 2024-07-10
US20240027349A1 (en) 2024-01-25
CN119937145A (zh) 2025-05-06
TWI794708B (zh) 2023-03-01
IL289312B2 (en) 2025-03-01
US20250123208A1 (en) 2025-04-17
WO2021138633A1 (en) 2021-07-08
AU2020418180A1 (en) 2022-01-06
MX2021016073A (es) 2022-03-25

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