TWI800483B - 抗人類血紅素單株抗體或抗體套組、抗人類血紅素單株抗體固定化不可溶性載體粒子、及使用其等之測定試劑或測定方法 - Google Patents

抗人類血紅素單株抗體或抗體套組、抗人類血紅素單株抗體固定化不可溶性載體粒子、及使用其等之測定試劑或測定方法 Download PDF

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Publication number
TWI800483B
TWI800483B TW106117708A TW106117708A TWI800483B TW I800483 B TWI800483 B TW I800483B TW 106117708 A TW106117708 A TW 106117708A TW 106117708 A TW106117708 A TW 106117708A TW I800483 B TWI800483 B TW I800483B
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TW
Taiwan
Prior art keywords
heme
monoclonal antibody
npmd
nite
insoluble carrier
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TW106117708A
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English (en)
Chinese (zh)
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TW201802472A (zh
Inventor
安居良太
油井惠
牧之段満
関泰宏
坂西千紗
Original Assignee
日商榮研化學股份有限公司
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Publication of TW201802472A publication Critical patent/TW201802472A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G01N33/546—Synthetic resin as water suspendable particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
TW106117708A 2016-05-30 2017-05-26 抗人類血紅素單株抗體或抗體套組、抗人類血紅素單株抗體固定化不可溶性載體粒子、及使用其等之測定試劑或測定方法 TWI800483B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016107343 2016-05-30
JP??2016-107343 2016-05-30

Publications (2)

Publication Number Publication Date
TW201802472A TW201802472A (zh) 2018-01-16
TWI800483B true TWI800483B (zh) 2023-05-01

Family

ID=60477766

Family Applications (1)

Application Number Title Priority Date Filing Date
TW106117708A TWI800483B (zh) 2016-05-30 2017-05-26 抗人類血紅素單株抗體或抗體套組、抗人類血紅素單株抗體固定化不可溶性載體粒子、及使用其等之測定試劑或測定方法

Country Status (10)

Country Link
US (1) US11175292B2 (https=)
EP (1) EP3467498B1 (https=)
JP (2) JP6991968B2 (https=)
KR (1) KR102433648B1 (https=)
CN (1) CN110383067B (https=)
AU (1) AU2017275081B2 (https=)
ES (1) ES2985318T3 (https=)
SG (1) SG11201809558PA (https=)
TW (1) TWI800483B (https=)
WO (1) WO2017209001A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202102265UA (en) * 2018-09-26 2021-04-29 Eiken Chemical Hemoglobin assay reagent, assay kit and assay method
CN112979799B (zh) * 2019-12-18 2022-11-08 东莞市朋志生物科技有限公司 一种包含血红蛋白抗原结构域的结合蛋白
CN111057150B (zh) * 2019-12-30 2021-10-29 深圳开立生物医疗科技股份有限公司 一种乳胶微球及其应用以及糖化血红蛋白检测试剂盒
CN114478759A (zh) * 2020-11-12 2022-05-13 东莞市朋志生物科技有限公司 抗人血红蛋白的抗体及其应用和诊断试剂盒

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI235159B (en) * 1999-06-30 2005-07-01 Dev Center Biotechnology Anti-human hemoglobin monoclonal antibodies for detecting fecal occult blood, producing hybridomas and uses thereof
US20080227208A1 (en) * 2007-03-16 2008-09-18 Hsiao-Ching Yee Devices and Methods for Detection of Occult Blood

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61137064A (ja) 1984-12-07 1986-06-24 Fujirebio Inc 大腸癌の予備スクリ−ニング方法
JPH02193071A (ja) 1989-01-20 1990-07-30 Green Cross Corp:The ハプトグロビン―ヘモグロビン複合体測定用試薬キット及びそれを用いるハプトグロビン―ヘモグロビン複合体の測定法
JPH05322888A (ja) * 1992-05-18 1993-12-07 Toyobo Co Ltd 遊離ヘモグロビンの定量方法および遊離ヘモグロビン定量キット
US5552295A (en) * 1994-03-02 1996-09-03 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies to bovine haptoglobin and methods for detecting serum haptoglobin levels
EP1179541B1 (en) * 1999-04-28 2004-06-16 Board Of Regents, The University Of Texas System Compositions and methods for cancer treatment by selectively inhibiting VEGF
JP2001221800A (ja) 2000-02-14 2001-08-17 Internatl Reagents Corp 複合体の測定方法
JP4390963B2 (ja) * 2000-04-05 2009-12-24 シスメックス株式会社 免疫測定方法及び試薬キット
CA2420770C (en) * 2000-08-29 2010-05-25 Kyowa Medex Co., Ltd. Highly reproducible agglutination immunoassay method and reagents
JP5227418B2 (ja) 2007-11-20 2013-07-03 エフ．ホフマン−ラ ロシュ アーゲー マーカー組み合わせカルプロテクチンおよびヘモグロビン／ハプトグロビン複合体の使用による便試料からの結腸直腸癌の評価方法
CN101236210A (zh) * 2008-01-29 2008-08-06 王学生 快速联检血红蛋白-结合珠蛋白复合物和大便潜血试剂
JP5191291B2 (ja) * 2008-07-04 2013-05-08 和光純薬工業株式会社 便検体中ヘモグロビンの測定方法及び測定試薬キット
EP2309265B1 (en) 2008-07-31 2013-07-17 Nitto Boseki CO., LTD. Method of assaying complex and kit to be used therefor
DE102012013888A1 (de) 2012-07-09 2014-05-22 Schebo Biotech Ag Testkit (Kombi-Schnelltest) zum synchronen Nachweis von Biomarkern im Stuhl zur Erkennung pathologischer Veränderungen im Gastrointestinaltrakt, insbesondere im Darm
CN104515859A (zh) * 2014-12-17 2015-04-15 杭州慧缘泰医疗器械有限公司 血红蛋白、血红蛋白-结合珠蛋白复合物、转铁蛋白联检试剂盒及其制备方法、检测方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI235159B (en) * 1999-06-30 2005-07-01 Dev Center Biotechnology Anti-human hemoglobin monoclonal antibodies for detecting fecal occult blood, producing hybridomas and uses thereof
US20080227208A1 (en) * 2007-03-16 2008-09-18 Hsiao-Ching Yee Devices and Methods for Detection of Occult Blood

Also Published As

Publication number Publication date
JP2022033935A (ja) 2022-03-02
CN110383067B (zh) 2023-07-21
EP3467498B1 (en) 2024-07-03
KR102433648B1 (ko) 2022-08-17
AU2017275081A1 (en) 2019-01-03
SG11201809558PA (en) 2018-12-28
JPWO2017209001A1 (ja) 2019-03-28
US11175292B2 (en) 2021-11-16
US20200319183A1 (en) 2020-10-08
AU2017275081B2 (en) 2023-12-07
EP3467498A4 (en) 2019-11-13
AU2017275081A2 (en) 2019-01-17
TW201802472A (zh) 2018-01-16
WO2017209001A1 (ja) 2017-12-07
JP6991968B2 (ja) 2022-01-13
JP7386220B2 (ja) 2023-11-24
KR20190015338A (ko) 2019-02-13
EP3467498A1 (en) 2019-04-10
ES2985318T3 (es) 2024-11-05
CN110383067A (zh) 2019-10-25

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