TWI711453B - 抑制水性點眼液中之洛赫西定類的殘存率降低之方法 - Google Patents

抑制水性點眼液中之洛赫西定類的殘存率降低之方法 Download PDF

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Publication number
TWI711453B
TWI711453B TW105117568A TW105117568A TWI711453B TW I711453 B TWI711453 B TW I711453B TW 105117568 A TW105117568 A TW 105117568A TW 105117568 A TW105117568 A TW 105117568A TW I711453 B TWI711453 B TW I711453B
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TW
Taiwan
Prior art keywords
eye drops
eye
acid
loxidine
contact lenses
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TW105117568A
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English (en)
Chinese (zh)
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TW201701881A (zh
Inventor
稻垣孝司
松本直樹
小川敏弘
若林祐喜久
神村明日香
大下善弘
中澤仁志
松岡功
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日商參天製藥股份有限公司
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW105117568A 2015-06-05 2016-06-03 抑制水性點眼液中之洛赫西定類的殘存率降低之方法 TWI711453B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015114595 2015-06-05
JP2015-114595 2015-06-05

Publications (2)

Publication Number Publication Date
TW201701881A TW201701881A (zh) 2017-01-16
TWI711453B true TWI711453B (zh) 2020-12-01

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ID=57440469

Family Applications (2)

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TW105117568A TWI711453B (zh) 2015-06-05 2016-06-03 抑制水性點眼液中之洛赫西定類的殘存率降低之方法
TW109122007A TWI743858B (zh) 2015-06-05 2016-06-03 使水性點眼液中之洛赫西定類安定化之方法

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TW109122007A TWI743858B (zh) 2015-06-05 2016-06-03 使水性點眼液中之洛赫西定類安定化之方法

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JP (4) JP6104433B2 (ja)
TW (2) TWI711453B (ja)
WO (1) WO2016195073A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019026992A1 (ja) * 2017-08-03 2019-02-07 参天製薬株式会社 クロルヘキシジンを含有する医薬組成物
JP6603785B2 (ja) * 2017-12-08 2019-11-06 千寿製薬株式会社 水溶性高分子を含む水性液剤
CN114761022B (zh) * 2019-11-29 2024-02-13 千寿制药株式会社 药物组合物
US20230145529A1 (en) 2020-03-31 2023-05-11 Santen Pharmaceutical Co., Ltd. Silver salt-containing ophthalmic aqueous composition filled in resin container

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104203254A (zh) * 2012-03-26 2014-12-10 参天制药株式会社 含有地夸磷索的滴眼液
TW201628626A (zh) * 2014-12-25 2016-08-16 參天製藥股份有限公司 水性點眼液

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09301858A (ja) * 1996-05-13 1997-11-25 Senju Pharmaceut Co Ltd グルコン酸クロルヘキシジン安定化水性薬剤
JPH1160505A (ja) * 1997-05-20 1999-03-02 Senju Pharmaceut Co Ltd 防腐組成物
JPH115744A (ja) * 1997-06-16 1999-01-12 Toa Yakuhin Kk ヒアルロン酸含有の外用水溶液製剤
JP2005263792A (ja) * 2004-02-19 2005-09-29 Santen Pharmaceut Co Ltd 澄明なラタノプロスト点眼液
JP2009073788A (ja) * 2007-09-21 2009-04-09 Teika Seiyaku Kk イソプロピルウノプロストン含有眼用組成物
WO2011016562A1 (ja) * 2009-08-07 2011-02-10 ロート製薬株式会社 シリコーンハイドロゲルコンタクトレンズ用眼科組成物
JP6047272B2 (ja) * 2010-09-15 2016-12-21 テイカ製薬株式会社 角膜上皮障害治療用点眼剤

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104203254A (zh) * 2012-03-26 2014-12-10 参天制药株式会社 含有地夸磷索的滴眼液
TW201628626A (zh) * 2014-12-25 2016-08-16 參天製藥股份有限公司 水性點眼液

Also Published As

Publication number Publication date
JP2017002036A (ja) 2017-01-05
JP6875884B2 (ja) 2021-05-26
JP7128305B2 (ja) 2022-08-30
TW202038974A (zh) 2020-11-01
TW201701881A (zh) 2017-01-16
JP2017114902A (ja) 2017-06-29
JP2021075534A (ja) 2021-05-20
JP6104433B2 (ja) 2017-03-29
WO2016195073A1 (ja) 2016-12-08
JP2022166224A (ja) 2022-11-01
TWI743858B (zh) 2021-10-21

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