TWI689311B - 用於製造Ｔａｕ蛋白產生促進劑，起因於缺乏Ｔａｕ蛋白之疾病的治療藥．預防藥及治療用．預防用食品組成物之組成物的使用 - Google Patents

用於製造Ｔａｕ蛋白產生促進劑，起因於缺乏Ｔａｕ蛋白之疾病的治療藥．預防藥及治療用．預防用食品組成物之組成物的使用 Download PDF

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TWI689311B
TWI689311B TW104136172A TW104136172A TWI689311B TW I689311 B TWI689311 B TW I689311B TW 104136172 A TW104136172 A TW 104136172A TW 104136172 A TW104136172 A TW 104136172A TW I689311 B TWI689311 B TW I689311B
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Taiwan
Prior art keywords
tau protein
earthworms
water
extract
live
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TW104136172A
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English (en)
Chinese (zh)
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TW201630616A (zh
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石井陽一
根本行
岡本猛
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日商井石有限公司
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/20—Natural extracts
    • A23V2250/204—Animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW104136172A 2014-11-04 2015-11-03 用於製造Ｔａｕ蛋白產生促進劑，起因於缺乏Ｔａｕ蛋白之疾病的治療藥．預防藥及治療用．預防用食品組成物之組成物的使用 TWI689311B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014-223977 2014-11-04
JP2014223977A JP6321521B2 (ja) 2014-11-04 2014-11-04 タウ蛋白産生促進剤、タウ蛋白の欠乏に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物

Publications (2)

Publication Number Publication Date
TW201630616A TW201630616A (zh) 2016-09-01
TWI689311B true TWI689311B (zh) 2020-04-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
TW104136172A TWI689311B (zh) 2014-11-04 2015-11-03 用於製造Ｔａｕ蛋白產生促進劑，起因於缺乏Ｔａｕ蛋白之疾病的治療藥．預防藥及治療用．預防用食品組成物之組成物的使用

Country Status (12)

Country Link
US (2) US10398740B2 (enExample)
EP (1) EP3216456B1 (enExample)
JP (1) JP6321521B2 (enExample)
KR (1) KR101948913B1 (enExample)
CN (1) CN106794199B (enExample)
AU (1) AU2015344361B2 (enExample)
BR (1) BR112017008734B1 (enExample)
CA (1) CA2964316C (enExample)
PH (1) PH12017500743B1 (enExample)
RU (1) RU2742658C2 (enExample)
TW (1) TWI689311B (enExample)
WO (1) WO2016072392A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017025019A (ja) * 2015-07-21 2017-02-02 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 アミロイドβ線維分解剤、アミロイドβの線維化に起因する疾患の治療薬・予防薬および治療用・予防用食品組成物
CN110191715B (zh) 2017-03-21 2020-11-10 井石有限会社 皮肤损伤治疗剂的制造方法及皮肤损伤治疗剂
TW201929877A (zh) * 2017-12-29 2019-08-01 大江生醫股份有限公司 地龍蛋白用於製造保護腦神經細胞醫藥組成物之用途

Citations (2)

* Cited by examiner, † Cited by third party
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WO2006082609A1 (en) * 2005-02-02 2006-08-10 Consiglio Nazionale Delle Ricerche Human ngf-like protein isolated from eisenia foetida an uses thereof
TW201235044A (en) * 2011-04-11 2012-09-01 Well Stone Co Manufacturing method for dried earthworm powder

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JPS5728007A (en) 1980-07-29 1982-02-15 Mitsuo Ishikura Preparation of colorless, transparent and tasteless earthworm extract
JPS59216572A (ja) 1983-05-20 1984-12-06 Yoichi Ishii ミミズ蛋白及び脂質健康食品
KR900012617A (ko) 1987-10-28 1990-09-01 요오이찌 이시이 혈전증 치료제 및 그 제조방법
JPH02215723A (ja) 1989-02-15 1990-08-28 Eimei:Kk 血圧調節剤
RU2177784C2 (ru) 1999-06-01 2002-01-10 Пермское научно-производственное объединение "Биомед" Энтеральный препарат, содержащий экстракт биомассы красного калифорнийского дождевого червя eisenia foetidae в виде таблеток "вермин"
CN1873005A (zh) * 2005-06-02 2006-12-06 中国科学院生物物理研究所 蚯蚓微管结合蛋白Tau、其编码基因及其应用
CN101095697A (zh) 2006-06-28 2008-01-02 李振国 水蛭和/或地龙分子量5800道尔顿以下的提取物
CN101543512B (zh) * 2008-03-28 2012-03-28 井石有限会社 蚯蚓干燥粉末的生产方法
TWI472329B (zh) * 2008-04-24 2015-02-11 必治妥美雅史谷比公司 埃坡徽素ｄ於治療包括阿茲海默症之ｔａｕ相關疾病的用途
JP4886017B2 (ja) * 2009-10-13 2012-02-29 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 ミミズ乾燥粉末の製造方法
KR101198192B1 (ko) 2011-04-11 2012-11-12 웰 스톤 유겐가이샤 지렁이 건조 분말의 제조 방법
KR101325004B1 (ko) * 2011-07-29 2013-11-04 웰 스톤 유겐가이샤 지렁이 건조 분말을 사용한 티로시나아제 저해제 및 그 제조 방법
JP5856725B2 (ja) 2011-08-02 2016-02-10 和夫 酒井 うつ病治療用または予防用医薬組成物
CN103251884B (zh) * 2013-05-03 2015-02-18 杨文明 治疗阿尔茨海默病的中药及其制备方法和应用
CN103550537B (zh) * 2013-11-10 2014-08-06 孟晓彬 一种治疗阿尔茨海默病的中药制剂及制备方法
CA2935315C (en) 2014-01-20 2022-07-19 Well Stone Co. Catecholamine production accelerator, and therapeutic and preventive agent and therapeutic and preventive food composition for diseases caused by catecholamine deficiency

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006082609A1 (en) * 2005-02-02 2006-08-10 Consiglio Nazionale Delle Ricerche Human ngf-like protein isolated from eisenia foetida an uses thereof
TW201235044A (en) * 2011-04-11 2012-09-01 Well Stone Co Manufacturing method for dried earthworm powder

Also Published As

Publication number Publication date
RU2017118158A3 (enExample) 2019-06-06
US20170348357A1 (en) 2017-12-07
RU2017118158A (ru) 2018-12-05
KR20170072348A (ko) 2017-06-26
TW201630616A (zh) 2016-09-01
CN106794199A (zh) 2017-05-31
EP3216456A1 (en) 2017-09-13
RU2742658C2 (ru) 2021-02-09
CA2964316C (en) 2024-05-14
CN106794199B (zh) 2021-03-23
EP3216456A4 (en) 2018-05-09
PH12017500743B1 (en) 2024-04-12
AU2015344361B2 (en) 2020-10-01
JP2016088877A (ja) 2016-05-23
BR112017008734B1 (pt) 2021-11-23
KR101948913B1 (ko) 2019-02-15
BR112017008734A2 (pt) 2018-02-27
WO2016072392A8 (ja) 2017-03-30
EP3216456B1 (en) 2020-09-16
US20190365826A1 (en) 2019-12-05
WO2016072392A1 (ja) 2016-05-12
PH12017500743A1 (en) 2017-10-09
US10398740B2 (en) 2019-09-03
JP6321521B2 (ja) 2018-05-09
CA2964316A1 (en) 2016-05-12
US10576108B2 (en) 2020-03-03
AU2015344361A1 (en) 2017-06-15

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