TWI659210B - 加強腫瘤生長的方法 - Google Patents

加強腫瘤生長的方法 Download PDF

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Publication number
TWI659210B
TWI659210B TW103127591A TW103127591A TWI659210B TW I659210 B TWI659210 B TW I659210B TW 103127591 A TW103127591 A TW 103127591A TW 103127591 A TW103127591 A TW 103127591A TW I659210 B TWI659210 B TW I659210B
Authority
TW
Taiwan
Prior art keywords
nme7
cells
human
cancer cells
cancer
Prior art date
Application number
TW103127591A
Other languages
English (en)
Chinese (zh)
Other versions
TW201537172A (zh
Inventor
辛席亞 班姆達德
Original Assignee
美商密內瓦生物技術公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2014/017515 external-priority patent/WO2014130741A2/en
Application filed by 美商密內瓦生物技術公司 filed Critical 美商密內瓦生物技術公司
Publication of TW201537172A publication Critical patent/TW201537172A/zh
Application granted granted Critical
Publication of TWI659210B publication Critical patent/TWI659210B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0271Chimeric vertebrates, e.g. comprising exogenous cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/12Animals modified by administration of exogenous cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/15Humanized animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0331Animal model for proliferative diseases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compounds Of Unknown Constitution (AREA)
TW103127591A 2013-08-12 2014-08-12 加強腫瘤生長的方法 TWI659210B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361865092P 2013-08-12 2013-08-12
US61/865,092 2013-08-12
??PCT/US14/17515 2014-02-20
PCT/US2014/017515 WO2014130741A2 (en) 2013-02-20 2014-02-20 Nme inhibitors and methods of using nme inhibitors

Publications (2)

Publication Number Publication Date
TW201537172A TW201537172A (zh) 2015-10-01
TWI659210B true TWI659210B (zh) 2019-05-11

Family

ID=52468797

Family Applications (1)

Application Number Title Priority Date Filing Date
TW103127591A TWI659210B (zh) 2013-08-12 2014-08-12 加強腫瘤生長的方法

Country Status (8)

Country Link
EP (2) EP3038462B1 (enExample)
JP (2) JP6640086B2 (enExample)
CN (1) CN105764334B (enExample)
AU (2) AU2014306778B2 (enExample)
CA (1) CA2921187A1 (enExample)
IL (1) IL244093B (enExample)
TW (1) TWI659210B (enExample)
WO (1) WO2015023694A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108513537A (zh) * 2015-09-23 2018-09-07 米纳瓦生物技术公司 筛选分化干细胞的试剂的方法
WO2018183654A1 (en) * 2017-03-29 2018-10-04 Minerva Biotechnologies Corporation Agents for differentiating stem cells and treating cancer
CN108434452A (zh) * 2018-03-13 2018-08-24 安徽瀚海博兴生物技术有限公司 一种将pd-1抗体和jmjd6联合用于制备抗癌药物的应用
CN116075318A (zh) 2020-06-26 2023-05-05 米纳瓦生物技术公司 抗nme抗体及治疗癌症或癌症转移的方法
WO2023201234A2 (en) 2022-04-12 2023-10-19 Minerva Biotechnologies Corporation Anti-variable muc1* antibodies and uses thereof
WO2025049494A1 (en) 2023-08-29 2025-03-06 Minerva Biotechnologies Corporation Bacterial nme7 orthologs and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102272290A (zh) * 2008-10-09 2011-12-07 米纳瓦生物技术公司 用于在细胞中诱导多能性的方法
WO2012126013A2 (en) * 2011-03-17 2012-09-20 Minerva Biotechnologies Corporation Method for making pluripotent stem cells
WO2013081188A1 (ja) * 2011-11-30 2013-06-06 独立行政法人国立がん研究センター 誘導悪性幹細胞

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8562988B2 (en) * 2005-10-19 2013-10-22 Ibc Pharmaceuticals, Inc. Strategies for improved cancer vaccines
US20090214483A1 (en) * 2005-06-30 2009-08-27 Weinberg Robert A Progenitor Cells and Uses Thereof
MX2008015492A (es) * 2006-06-06 2009-02-12 Univ Tennessee Res Foundation Composiciones enriquecidas en celulas madre neoplasicas y metodos que las contienen.
CN101855339A (zh) * 2007-01-22 2010-10-06 雷文生物技术公司 人类癌症干细胞
WO2012165287A1 (ja) * 2011-05-27 2012-12-06 公立大学法人横浜市立大学 人工癌幹細胞の作製方法及びその分化誘導方法
WO2013059373A2 (en) * 2011-10-17 2013-04-25 Minerva Biotechnologies Corporation Media for stem cell proliferation and induction
CA2880010A1 (en) * 2012-07-24 2014-01-30 Minerva Biotechnologies Corporation Nme variant species expression and suppression
KR20210082547A (ko) * 2013-02-20 2021-07-05 미네르바 바이오테크놀로지 코포레이션 Nme 저해제 및 nme 저해제의 사용 방법

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102272290A (zh) * 2008-10-09 2011-12-07 米纳瓦生物技术公司 用于在细胞中诱导多能性的方法
WO2012126013A2 (en) * 2011-03-17 2012-09-20 Minerva Biotechnologies Corporation Method for making pluripotent stem cells
WO2013081188A1 (ja) * 2011-11-30 2013-06-06 独立行政法人国立がん研究センター 誘導悪性幹細胞

Also Published As

Publication number Publication date
EP4233536A3 (en) 2023-10-25
AU2021200429B2 (en) 2023-05-11
IL244093A0 (en) 2016-04-21
AU2021200429A1 (en) 2021-02-25
CA2921187A1 (en) 2015-02-19
EP3038462B1 (en) 2023-03-15
JP6640086B2 (ja) 2020-02-05
AU2014306778B2 (en) 2020-10-29
AU2014306778A1 (en) 2016-03-03
JP6902577B2 (ja) 2021-07-14
IL244093B (en) 2022-01-01
JP2019213551A (ja) 2019-12-19
EP3038462A4 (en) 2017-06-14
WO2015023694A2 (en) 2015-02-19
JP2016527901A (ja) 2016-09-15
CN105764334A (zh) 2016-07-13
TW201537172A (zh) 2015-10-01
EP3038462A2 (en) 2016-07-06
CN105764334B (zh) 2020-07-28
WO2015023694A3 (en) 2015-04-23
EP4233536A2 (en) 2023-08-30
AU2021200429C1 (en) 2023-11-30

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