TWI646107B - Bcma及cd3之結合分子 - Google Patents

Bcma及cd3之結合分子 Download PDF

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Publication number
TWI646107B
TWI646107B TW103109750A TW103109750A TWI646107B TW I646107 B TWI646107 B TW I646107B TW 103109750 A TW103109750 A TW 103109750A TW 103109750 A TW103109750 A TW 103109750A TW I646107 B TWI646107 B TW I646107B
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sequence identification
cdr
region
sequence
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TW103109750A
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TW201506042A (zh
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彼得 庫佛
托畢斯 萊姆
派翠克 霍夫曼
羅曼 基斯契爾
瑞夫 路特布斯
多利斯 瑞伍
保羅 亞當
艾瑞克 鮑吉斯
芭芭拉 希貝斯
蘇珊 希普
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安進研究(慕尼黑)有限責任公司
安進公司
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
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    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor

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TW103109750A 2013-03-15 2014-03-14 Bcma及cd3之結合分子 TWI646107B (zh)

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US201361793235P 2013-03-15 2013-03-15
US61/793,235 2013-03-15

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TW201506042A TW201506042A (zh) 2015-02-16
TWI646107B true TWI646107B (zh) 2019-01-01

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EP (2) EP2970472A1 (cg-RX-API-DMAC7.html)
JP (2) JP6543197B2 (cg-RX-API-DMAC7.html)
KR (1) KR20150130412A (cg-RX-API-DMAC7.html)
CN (2) CN111484556A (cg-RX-API-DMAC7.html)
AR (1) AR095374A1 (cg-RX-API-DMAC7.html)
AU (2) AU2014230217B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015020277A2 (cg-RX-API-DMAC7.html)
CA (1) CA2899830C (cg-RX-API-DMAC7.html)
CL (1) CL2015002742A1 (cg-RX-API-DMAC7.html)
EA (1) EA201591692A1 (cg-RX-API-DMAC7.html)
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IL (1) IL241332A0 (cg-RX-API-DMAC7.html)
MX (1) MX372679B (cg-RX-API-DMAC7.html)
PE (1) PE20151920A1 (cg-RX-API-DMAC7.html)
PH (1) PH12015501672A1 (cg-RX-API-DMAC7.html)
SG (1) SG11201506184WA (cg-RX-API-DMAC7.html)
TW (1) TWI646107B (cg-RX-API-DMAC7.html)
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