TWI618546B - Emulsified composition - Google Patents

Abstract

The method for producing an emulsified composition of the present invention comprises, after the step 1, a step 2 of mixing and emulsifying the aqueous phase I containing the following components (A), (B), (C), (D) and (F1). And cooling: (A) 0.001 to 10% by mass of the compound represented by the following formula (1) (Z ¹ is a structure having two or more hydroxyl groups of glycerin, sorbitan, sorbitol or sucrose residue, Y ¹ is an ester bond or an ether bond, R is a hydrocarbon group of C14-22, and n is 1~ (4) 0.001 to 10% by mass of (C) one or more compounds selected from the group consisting of higher alcohols and sterols of C14-22, and (C) 0.001 to 15% by mass of the compound represented by the formula (2) (R ¹ is a hydrocarbon group of C4~30; Z is a methylene group, methine group or O; X ¹ , X ² and X ³ are H, OH or ethoxylated groups, and X ⁴ is H, ethyl hydrazine or glycerol R ² and R ³ are H, OH, hydroxymethyl or acetoxymethyl; R ⁴ is a C5-60 hydrocarbon group; R ⁵ is H, C1~30 hydrocarbon group), (D) anionic surfactant 0.00025~10% by mass, and (F1) water; Step 2 further mixes the aqueous phase II containing the following components: (E) is selected from the group consisting of alkyl modified polyacrylic ethylene polymers and alkyl modified polysaccharide polymers The water-soluble polymer in the range is 0.001 to 6% by mass, and (F2) water.

Description

Emulsified composition

This invention relates to an emulsified composition.

There are keratinocytes in the stratum corneum of the outermost layer of the skin and intercellular lipids filling the gap. Most of them are formed with an α-gel structure, and have the following functions on the skin: inhibiting penetration of substances from the outside, evaporation of moisture from the inside, and maintaining moisture by itself, thereby maintaining the softness or smooth appearance of the skin.

It is generally known that the skin condition caused by the decrease in intercellular lipids, particularly ceramide, is poor, and it can be considered that topical supplementation of ceramide is associated with a decrease in the function of the skin.

However, since ceramide has a high melting point and high crystallinity, it is difficult to prepare it in an external preparation or the like, and various studies have been conducted on stable formulation.

For example, Patent Document 1 discloses that an emulsified composition obtained by combining ceramide, a monoglyceride, and a higher alcohol in a specific ratio suppresses crystal precipitation of ceramide, and forms α which is easy to retain moisture. The gel structure has a high moisturizing effect.

Further, it has been studied to further improve the moisture retention ability of the α-gel by further combining a specific sugar alcohol or a disaccharide or a trisaccharide, so that the moisture remains on the skin for a long period of time, and the state of the skin is improved (Patent Literature) 2. Patent Document 3).

However, although these compositions form an α-gel structure, they have a low viscosity and are difficult to apply to the skin, so even if a film having a moisturizing effect is formed, the skin The film is also fragile and does not cover the skin evenly, making it difficult to maintain adequate moisture retention.

Further, since the film lacks flexibility and elasticity, the skin after application has a unique rubbing feeling and a rough feeling, and a good feeling of use cannot be obtained. Further, there is also a problem that the appearance after application lacks smoothness, and the effect of improving the appearance of the skin cannot be obtained.

[Previous Technical Literature] [Patent Literature]

[Patent Document 1] Japanese Patent Laid-Open Publication No. 2007-22997

[Patent Document 2] Japanese Patent Laid-Open Publication No. 2011-32265

[Patent Document 3] Japanese Patent Laid-Open Publication No. 2011-32266

The invention provides a method for producing an emulsified composition, which comprises the step 2 after the step 1, the step 1 is to make the water phase I containing the following components (A), (B), (C), (D) and (F1) Mixing, emulsifying, and cooling: (A) 0.001 to 10% by mass of the compound represented by the following formula (1) (wherein Z ¹ represents a structure having two or more hydroxyl groups of glycerin, sorbitan, sorbitol or sucrose residue, Y ¹ represents an ester bond or an ether bond, and R represents a hydrocarbon group having 14 to 22 carbon atoms. (n) is a number of 1 to 4), (B) is 0.001 to 10% by mass of one or more compounds selected from the group consisting of higher alcohols and sterols having a carbon number of 14 to 22, and (C) is represented by the formula (2) 0.001 to 15% by mass of the compound (wherein R ¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 4 to 30 carbon atoms which may be substituted by a hydroxyl group, a carbonyl group or an amine group; and Z represents a methylene group, a methine group or an oxygen atom; X ¹ , X ² and X ³ each independently represent a hydrogen atom, a hydroxyl group or an ethoxylated group, and X ⁴ represents a hydrogen atom, an ethenyl group or a glyceryl group, or forms a pendant oxy group together with an adjacent oxygen atom (however, Z is a methine group, X ¹ and X ² according to any one of a hydrogen atom, the other is absent .X ⁴ forming the side group, X ³ does not exist); R ² and R ³ each independently represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an ethoxymethyl group; R ⁴ represents a linear chain having a carbon number of 5 to 60 which may be substituted with a hydroxyl group, a carbonyl group or an amine group and may have an ether bond, an ester bond or a guanamine bond in the main chain. a branched or cyclic saturated or unsaturated hydrocarbon group; R ⁵ represents a hydrogen atom, or represents a total carbon number of from 1 to 30 which may have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group and an ethoxy group. a linear or branched saturated or unsaturated hydrocarbon group; a dotted line indicating that it can be an unsaturated bond), (D) an anionic surfactant 0.00025 to 10% by mass, (F1) water; and a step 2 The aqueous phase of the following components II: (E) is selected from alkyl-modified vinyl polymers and polyacrylic polymers of alkyl-modified polysaccharide-based water-soluble polymer, 0.001 to 6% by mass, and (F2) water.

Further, the present invention provides an emulsified composition comprising the following components (A), (B), (C), (D), (E) and (F): (A) glycerol monobehenate or glycerol single Cetyl ether 0.001 to 10% by mass, (B) cetyl alcohol or stearyl alcohol 0.001 to 10% by mass, (C) ceramides represented by the general formula (3) or the general formula (4) 0.001 to 15 mass % (wherein R ¹¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 7 to 19 carbon atoms which may be substituted by a hydroxyl group; Z ₁ represents a methylene group or a methine group; X ⁵ and X ⁶ and X ⁷ each independently represents a hydrogen atom, a hydroxyl group or an ethyloxy group; X ⁸ represents a hydrogen atom or forms a pendant oxy group together with an adjacent oxygen atom (however, when Z ₁ is a methine group, X ⁵ and X ^{6 are used} ) One is a hydrogen atom and the other is absent. When X ⁸ forms a pendant oxy group, X ⁷ is absent); R ¹² represents a hydroxymethyl group or an ethoxymethyloxy group; R ¹³ represents a hydrogen atom, or represents a carbon number of 1 Alkyl group of ~4; R ¹⁴ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 30 carbon atoms which may be substituted by a hydroxyl group, or may be represented by an ω terminal ester bond of the alkyl group. A hydroxy group substituted with a linear or branched saturated or unsaturated fatty acid having a carbon number of 8 to 22; a dotted line indicating an unsaturated bond) [Chemical 4] (wherein R ¹⁵ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom which may be substituted with a hydroxyl group and has a carbon number of 10 to 22; X ⁹ represents a hydrogen atom, an ethyl fluorenyl group or a glyceryl group; ¹⁶ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 22 carbon atoms which may be substituted by a hydroxyl group or an amine group, or a carbon number which may be substituted by a hydroxyl group at the ω terminal ester of the hydrocarbon group a linear or branched saturated or unsaturated fatty acid of 8 to 22; R ¹⁷ represents a hydrogen atom, or represents a total carbon number of 1 to 30 which may be substituted by a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an ethoxy group. Alkyl), (D) stearyl glutamate, stearyl methyl taurate or polyoxyethylene stearyl ether 0.0225 to 10% by mass, (E) (acrylic acid / acrylonitrile) Base (C10-30)) copolymer, (alkyl acrylate / stearyl methacrylate-20) copolymer, laureth-13PG hydroxyethyl cellulose or stearoxy PG hydroxy group B Sodium cellulose sulfonate 0.001 to 6% by mass, and (F) water.

The emulsified composition of the present invention can obtain high viscosity and elastic liquidity, and the coating film has flexibility and elasticity, so that the skin can be uniformly covered, the moisture retaining ability can be improved, the skin feels smooth, and the appearance can be made smooth.

The present invention relates to a coating film which has flexibility and elasticity and can be uniformly coated. An emulsified composition that covers the skin, improves moisture retention, smoothes the skin, and smoothes the appearance.

The present inventors have found that a highly viscous and elastic liquid property can be obtained by combining a specific water-soluble polymer with a designed α-gel having improved water retention ability, so that the coating film has flexibility and elasticity, and thus An emulsified composition is obtained which can uniformly cover the skin, improve the moisture retaining ability, and has a smooth touch and smooth appearance.

The component (A) used in the present invention is represented by the above formula (1).

In the formula, the hydrocarbon group having 14 to 22 carbon atoms represented by R is preferably a linear hydrocarbon group, and examples thereof include a linear alkyl group such as a myristyl group, a palmity group, a stearyl group, and a behenyl group; , oleyl (oleyl) and the like.

Examples of the compound represented by the formula (1) include glycerin mono-fatty acid ester, sorbitan mono-fatty acid ester, sorbitan di-fatty acid ester, sorbitol mono-fatty acid ester, and sorbitol II. Fatty acid esters, sucrose mono-fatty acid esters, glycerol monoalkyl ethers, and the like.

As the component (A), a glycerin mono-fatty acid ester, a sorbitan mono-fatty acid ester, or a glycerin monoalkyl ether is preferable. Among them, preferred are glycerol monopalmitate, glyceryl monostearate, glycerol monobehenate, sorbitan monostearate, glycerol monocetyl ether, glyceryl monostearyl ether; From the viewpoint of improving the formability and water retention of the following flaky film, glyceryl monobehenate or glycerol monocetyl ether is more preferable.

The component (A) may be used singly or in combination of 0.001 to 10% by mass, preferably 0.05 to 7% by mass, more preferably 0.25 to 3% by mass, based on the total composition. If it is within this range, the emulsified composition of the present invention is applied to the skin. Thereafter, a flaky film in which the lipid layer and the water layer composed of the following components (B) to (E) are alternately arranged is formed on the surface of the skin during the drying process. As a result, it is preferable to retain moisture between the layers and to improve the water retaining ability. Further, the touch feeling of the coating film is also improved, so that it is preferable.

In the component (B) used in the present invention, the higher alcohol has a carbon number of 14 to 22, preferably a carbon number of 16 to 18. For example, myristyl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, etc. are mentioned.

Among these, cetyl alcohol and stearyl alcohol are preferable, and cetyl alcohol is further preferable.

Further, in the component (B), examples of the sterols include cholesterol and phytosterols. Plant sterols are a general term for plant sterols such as β-sitosterol, rapeseed sterol, soybean sterol, and rapeseed sterol, and the composition thereof is not limited.

The component (B) may be used singly or in combination of 0.001 to 10% by mass, preferably 0.05 to 7% by mass, more preferably 0.1 to 3% by mass, based on the total composition. If it is in this range, after apply|coating the emulsion composition of this invention on skin, it can comprise the above-mentioned component (A) and the following components (C)- (E) on the skin surface in the drying process. The flaky film in which the lipid layer and the water layer are alternately arranged. As a result, it is preferable to retain moisture between the layers and to improve moisture barrier properties. Further, since the appearance of the skin after application is also improved, it is preferable.

The component (C) ceramide used in the present invention is represented by the above formula (2).

Wherein R ¹ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group which may be substituted with a hydroxyl group, a carbonyl group or an amine group and has a carbon number of 4 to 30, preferably a hydroxyl group substituted with a carbon number of 7 to 22; , or a hydrogen atom.

Z represents either a methylene group, a methine group or an oxygen atom.

X ¹ , X ² and X ³ each independently represent a hydrogen atom, a hydroxyl group or an ethoxy group. Preferably, 0 to 1 of X ¹ , X ² and X ³ are a hydroxyl group, and the balance is a hydrogen atom. When Z is a methine group, only one of X ¹ and X ² is a hydrogen atom, and the other is not present. Further, X ^{4 is} preferably a hydrogen atom or a glyceryl group.

R ² and R ³ represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an ethoxymethyl group. Preferably, R ² is a hydrogen atom or a hydroxymethyl group, and preferably R ³ is a hydrogen atom.

R ⁴ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 60 carbon atoms which may be substituted with a hydroxyl group, a carboxyl group or an amine group and may have an ether bond, an ester bond or a guanamine bond in the main chain. Preferably, a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 35 carbon atoms which may be substituted by a hydroxyl group or an amine group is used, or an ester bond or a guanamine bond is bonded to the ω position of the hydrocarbon group. A linear, branched or cyclic saturated or unsaturated fatty acid having a carbon number of 8 to 22 which may be substituted by a hydroxyl group. As the fatty acid to be bonded, isostearic acid, 12-hydroxystearic acid or linoleic acid is preferred.

R ⁵ represents a hydrogen atom, or a may have a group selected from hydroxy, hydroxyalkoxy, alkoxy and substituted acetyl group in the total number of carbons of the saturated straight-chain or branched, of 1 to 30 or unsaturated hydrocarbon chains . When R ¹ is a hydrogen atom and Z is an oxygen atom, R ⁵ is a hydrocarbon group having a total carbon number of 10 to 30. Further, when R ¹ is a hydrocarbon group, R ⁵ is a hydrocarbon group having a total carbon number of 1 to 8. Among these, a hydrogen atom or a hydrocarbon group having a total carbon number of 1 to 8 which is substituted with one to three substituents selected from a hydroxyl group, a hydroxyalkoxy group and an alkoxy group is preferable. Here, as the hydroxyalkoxy group and the alkoxy group, those having 1 to 7 carbon atoms are preferable.

The compound represented by the formula (2) is preferably a ceramide which is represented by the following formula (3) or (4).

(I) The compound represented by the formula (3) may be derived from natural ceramide or the same a composite of structures.

(Wherein, R ¹¹ represents a hydroxyl group may be substituted with a carbon number of 7 to 19 of the straight-chain, branched or cyclic saturated or unsaturated hydrocarbon group of; Z ₁ represents a methylene group or a methine group; X ^5, X ⁶ and X ⁷ each independently represents a hydrogen atom, a hydroxyl group or an ethyloxy group; X ⁸ represents a hydrogen atom or forms a pendant oxy group together with an adjacent oxygen atom (however, when Z ₁ is a methine group, X ⁵ and X ^{6 are used} ) One is a hydrogen atom and the other is absent. When X ⁸ forms a pendant oxy group, X ⁷ is absent); R ¹² represents a hydroxymethyl group or an ethoxymethyloxy group; R ¹³ represents a hydrogen atom, or represents a carbon number of 1 Alkyl group of ~4; R ¹⁴ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 30 carbon atoms which may be substituted by a hydroxyl group, or may be represented by an ω terminal ester bond of the alkyl group. a hydroxy group substituted with a linear or branched saturated or unsaturated fatty acid having a carbon number of 8 to 22; a dotted line indicating an unsaturated bond)

The following compounds may be mentioned: R ^{11 is} preferably a linear alkyl group having a carbon number of 7 to 19, more preferably 13 to 15 carbon atoms; and R ¹⁴ is a linear alkyl group or ester having a carbon number of 9 to 27 which may be substituted by a hydroxyl group. The bond has a linear alkyl group of 9 to 27 carbon atoms of linoleic acid. Further, X ⁸ preferably represents a hydrogen atom or forms a pendant oxy group together with an oxygen atom. Further, as R ¹⁴ , a tetradecyl group, a 1-hydroxypentadecyl group, a 1-hydroxytetracosyl group, a heptadecyl group, a 1-hydroxyundecyl group, and the ω position are preferable. The ester bond is a octadecyl group of linoleic acid.

Specific examples of the natural ceramide include sphingosine 1 to 7 which is succinylated by sphingosine, dihydrosphingosine, phytosphingosine or sphingamine diol (for example, J). .Lipid Res., Fig. 2 of 24:759 (1983) and pigs and human ceramides of Fig. 4 of J. Lipid. Res., 35:2069 (1994).

Further, these N-alkyl groups (for example, N-methyl groups) are also contained.

These ceramides may be optically active (D(-)), or optically active (L(+)), and a mixture of natural and non-natural. . The relative configuration of the above compounds may be either a natural type configurator, a non-natural type configurator other than the above, or a mixture of such a mixture. Among them, preferred are CERAMIDE 1, CERAMIDE 2, CERAMIDE 3, CERAMIDE 5, CERAMIDE 6II compounds (the above are INCI (International Nomenclature of Cosmetic Ingredients); 8th edition) and the following formula .

These may be any of natural extracts and compositions, and commercially available products may also be used.

As a commercial product of such natural ceramide, Ceramide I, Ceramide III, Ceramide IIIA, Ceramide IIIB, Ceramide IIIC, Ceramide VI (above, manufactured by Cosmofarm), and Ceramide TIC-001 (High Sand Spice Co., Ltd.) are mentioned. , CERAMIDE II (Quest International), DS-Ceramide VI, DS-CLA-Phytoceramide, C6-Phytoceramide, DS-Ceramide Y3S (DOOSAN), CERAMIDE 2 (Sederma).

(II) pseudo-cerebralamine represented by the formula (4).

(wherein R ¹⁵ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom which may be substituted with a hydroxyl group and has a carbon number of 10 to 22; X ⁹ represents a hydrogen atom, an ethyl fluorenyl group or a glyceryl group; ¹⁶ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 22 carbon atoms which may be substituted by a hydroxyl group or an amine group, or a carbon number which may be substituted by a hydroxyl group at the ω terminal ester of the hydrocarbon group a linear or branched saturated or unsaturated fatty acid of 8 to 22; R ¹⁷ represents a hydrogen atom, or represents a total carbon number of 1 to 30 which may be substituted by a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an ethoxy group. Alkyl)

As R ¹⁶ , a decyl group, a tridecyl group, a pentadecyl group, an undecyl group bonded with linoleic acid at the ω position, and an oleic acid at the ω position are bonded thereto. The pentaalkyl group is esterified with a pentadecyl group of 12-hydroxystearic acid at the ω position, and an undecyl group having a methyl branched isostearic acid bonded to the oxime at the ω position.

R ^{17 is} preferably a total carbon number of 10 to 30, preferably a total carbon number, which may be substituted by a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an ethoxy group when R ¹⁵ is a hydrogen atom. An alkyl group of 12 to 20; in the case where R ¹⁵ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having a carbon number of 10 to 22 which may be substituted by a hydroxyl group, it represents a hydrogen atom or represents a hydroxyl group. An alkyl group having a total carbon number of 1 to 8 substituted by a hydroxyalkoxy group, an alkoxy group or an ethoxylated group. The hydroxyalkoxy group or alkoxy group of R ¹⁷ is preferably a carbon number of 1 to 7.

As the general formula (4), R ¹⁵ is a hexadecyl group, X ⁹ is a hydrogen atom, R ¹⁶ is a pentadecyl group, and R ¹⁷ is a hydroxyethyl group; R ¹⁵ is a hexadecyl group, and X ⁹ is a group Is a hydrogen atom, R ¹⁶ is a fluorenyl group, and R ¹⁷ is a hydroxyethyl group; or R ¹⁵ is a hexadecyl group, X ⁹ is a glyceryl group, R ¹⁶ is a tridecyl group, and R ¹⁷ is a 3-methoxy group. a pseudo-cephalamine of the group; more preferably, R ¹⁵ of the formula (4) is a hexadecyl group, X ⁹ is a hydrogen atom, R ¹⁶ is a pentadecyl group, and R ¹⁷ is a hydroxyethyl group (N- (hexadecyloxyhydroxypropyl)-N-hydroxyethylhexadecaneamine).

The compound of the component (C) may be used alone or in combination of the total composition. 0.001 to 15% by mass, preferably 0.05 to 7% by mass, more preferably 0.5 to 5% by mass. Within this range, after the emulsion composition of the present invention is applied to the skin, the above components (A), (B), and the following components (D)~ can be formed on the skin surface during the drying process. E) A flaky film in which the lipid layer and the water layer are alternately arranged. As a result, moisture can be maintained between the layers. Further, in the emulsified composition of the present invention and the flaky film formed after coating and drying, the component (C) does not crystallize. As a result, the component (C) can be highly penetrated into the skin, which is preferable. Further, it is preferable because it improves the appearance of the skin after application and the feeling of use.

Examples of the component (D) anionic surfactant used in the present invention include fatty acid salts having a carbon number of 12 to 24 such as sodium laurate, potassium palmitate, and stearic acid; sodium lauryl sulfate and lauryl An alkyl sulfate salt such as potassium sulfate; an alkyl ether sulfate salt such as polyoxyethylene lauryl sulfate triethanolamine; N-mercapto myosamine such as sodium lauryl sarcosinate; N-stearyl sulfhydryl-N - fatty acid decyl sulfonate such as sodium methyl taurate, N-myristyl-N-methyl taurate; alkyl phosphate such as sodium monostearyl phosphate; polyoxyethylene oleate sodium phosphate Polyoxyethylene alkyl ether phosphate such as polyoxyethylene stearyl ether sodium phosphate; long chain sulfosuccinate such as sodium di-2-ethylhexyl sulfosuccinate; N-lauric acid glutamic acid monosodium , N-stearyl-L-glutamate, N-stearyl-L-glutamic acid, N-stearyl glutamate, N-myristyl-L - Long-chain N-mercapto glutamate such as sodium glutamate.

Among these, a fatty acid salt having 12 to 24 carbon atoms, an alkyl sulfate ester salt, an alkyl ether sulfate salt, a fatty acid decyl sulfonate, an alkyl phosphate, a polyoxyethylene alkyl ether phosphate is preferred. Long chain N-mercapto glutamate.

Among them, preferred are stearyl glutamate, stearyl methyl taurate, polyoxyethylene stearyl ether phosphate, more preferably stearyl glutamate, stearyl sulfonate Methyl taurate, and more preferably stearyl glutamate.

The salt of the component (D) is preferably one or more selected from the group consisting of a sodium salt, a potassium salt, a basic amino acid salt, and ammonium, and is preferably selected from the viewpoint of exhibiting the viscosity of the emulsified composition. One or more of the sodium salt and the arginine salt.

The component (D) may be formulated as an acid or may be neutralized by a base to be contained in the form of a salt. In this case, the base of the component (D) is preferably one or more selected from the group consisting of a basic amino acid, sodium hydroxide, potassium hydroxide, triethanolamine, and calcium hydroxide, and a basic amino group. The acid is preferably one or more selected from the group consisting of arginine, lysine, and histidine. The base of the neutralizing component (D) is preferably one or two selected from the group consisting of arginine and sodium hydroxide from the viewpoint of exhibiting the viscosity of the emulsified composition. More preferably arginine.

The component (D) may be used alone or in combination, and is contained in an amount of 0.00025 to 10% by mass, preferably 0.05 to 2% by mass, more preferably 0.1 to 1% by mass in the total composition. If it is in this range, component (A)-(C) can be emulsified. Further, after the emulsified composition of the present invention is applied to the skin, a lipid layer composed of the components (A) to (D) and the component (E) and the water layer are alternately arranged on the surface of the skin during the drying process. a flaky film. As a result, it is preferable to retain moisture between the layers and to promote the water retaining ability.

The component (E) used in the present invention is a water-soluble polymer selected from the group consisting of an alkyl-modified polyacrylic polymer and an alkyl-modified polysaccharide-based polymer.

For example, an alkyl acrylate copolymer, (meth)acrylic acid / (A) Alkyl acrylate copolymer, alkyl acrylate-alkyl methacrylate-polyoxyethylene stearyl ether copolymer, polysaccharide derivative, and the like.

More specifically, (acrylic acid/alkyl acrylate (C10-30)) copolymer, (alkyl acrylate/stearyl methacrylate-20) copolymer, laureth- 13PG hydroxyethyl cellulose, stearyloxy PG hydroxyethyl cellulose sulfonate, and the like.

As a commercial item, for example, Aculyn 33 (The Dow Chemical Company) can be cited as the alkyl acrylate polymer, and as a (meth)acrylic acid/alkyl (meth) acrylate copolymer, Pemulen TR-1 can be cited. , Pemulen TR-2, Carbopol ETD2020 (above manufactured by Lubrizol Advanced Materials, Inc.) and the like. Further, examples of the alkyl acrylate-alkyl methacrylate-polyoxyethylene stearyl ether copolymer include Aculyn 22 (The Dow Chemical Company). Examples of the polysaccharide derivative include SPS-S-SA, SOFCARE EP-S (above, manufactured by Kao Corporation), and Natrosol Plus (Hercules-Aqualon).

The component (E) may be used singly or in combination of 0.001 to 6% by mass, preferably 0.05 to 5% by mass, more preferably 0.1 to 3% by mass, based on the total composition. If it is in this range, the storage stability of the emulsified composition of this invention can be improved. Further, crystallization of the lipid mixture composed of the components (A) to (D) can be suppressed. As a result, it is possible to impart flexibility to the flaky film formed on the surface of the skin after drying by applying the emulsified composition of the present invention. As a result, it is preferable because it has a function of retaining moisture, improving the feeling of use, and improving the appearance of the skin after application.

In the present invention, the component (F) water constitutes the remainder of each component, preferably It is contained in the total composition of 49 to 85% by mass, more preferably 55 to 80% by mass.

In the present invention, the mass ratio of the components (A), (B), (C), (D) and (E) is preferably (E) / (in terms of obtaining high viscosity and elastic liquidity). (A) + (B) + (C)) = 0.0025 to 50, further preferably (E) / ((A) + (B) + (C)) = 0.01 to 3, and particularly preferably (E) / ((A)+(B)+(C))=0.1~1.5. As a result, when applied to the skin, a high coating feeling can be felt, and a good feeling of use can be imparted.

Further, in order to obtain a film having flexibility and elasticity, it is preferably (E) / (D) = 0.025 to 100, more preferably (E) / (D) = 0.14 to 7.5, and particularly preferably (E) / (D) = 1.2~6.

In the present invention, it is more preferred to combine the preferred components and preferred contents of the above components.

Further, in the emulsified composition of the present invention, it is preferred that the component (A) is glycerol monobehenate or glycerin monocetyl ether, and the component (B) is cetyl alcohol or stearyl alcohol, and the component (C) The compound represented by the formula (1), the component (D) is stearyl glutamate, stearyl methyl taurate or polyoxyethylene stearyl ether phosphate, and the component (E) is (acrylic acid/alkyl acrylate (C10-30)) copolymer, (alkyl acrylate/stearyl methacrylate-20) copolymer, laureth-13PG hydroxyethyl cellulose or stearic acid Sodium oxy hydroxyethyl cellulose sulfonate, component (F) is water.

Further, in the emulsified composition of the present invention, it is preferred that: Component (A) is glycerol monobehenate, component (B) is cetyl alcohol, component (C) is a compound represented by the formula (1), and component (D) is stearyl glutamate. Ingredient (E) is (acrylic acid/alkyl acrylate (C10-30)) copolymer, (alkyl acrylate/stearyl methacrylate-20) copolymer, laureth-13PG hydroxyethyl Cellulose or sodium stearyl PG hydroxyethyl cellulose sulfonate, component (F) is water.

In the present invention, the lipids of the emulsion are formed from the components (A) to (D). When these are dried, crystallization occurs to form a hard and brittle film, and a film having a high moisture retention property cannot be obtained. However, it is known that by further containing the component (E), crystallization of the lipid can be suppressed, and a flaky soft film containing a large amount of water and having a lipid layer and an aqueous layer alternately arranged can be formed. In particular, when cetyl alcohol is used as the component (B), the softness of the film is increased, and the smoothness of the appearance and touch of the skin is improved. Further, the use of the emulsified composition of the present invention for producing a skin coating agent, the use of the emulsified composition of the present invention for producing a moisture retaining agent for skin, and the coating film forming agent for producing a skin can be provided. Use of the emulsified composition of the present invention.

The emulsified composition of the present invention may further contain an oil component other than the components (B) and (C). For example, a hydrocarbon oil such as liquid paraffin, squalane or petrolatum; an ether oil such as cetyl dimethyl butyl ether, ethylene glycol dioctyl ether or glycerin monooleate; octyl dodecyl myristate; Isopropyl palmitate, butyl stearate, di-2-ethylhexyl adipate, neopentyl glycol dicaprate, glycerol trioctane Ester oils such as acid esters; higher fatty acids such as stearic acid, behenic acid, isomyristate; vegetable oils such as olive oil; dimethyl polyoxyalkylene, cyclic dimethyl polyoxyalkylene, methyl phenyl poly Alkoxysilane, amine modified polyoxyl, carboxyl modified polyoxyl, alcohol modified polyoxyl, alkyl modified polyoxyl, polyether modified polyoxygen, fluorine modified polyoxyl Oxygenated oil; perfluoroalkylethylphosphoric acid, perfluoroalkyl polyoxyethylene phosphate, perfluoropolyether, polytetrafluoroethylene and other fluorine-based oils. These oily components are preferably contained in an amount of 0 to 20% by mass based on the total composition.

Further, the emulsified composition of the present invention may contain an active ingredient or an additive used in a usual cosmetic, such as water-soluble vitamins such as ascorbic acid, niacinamide, niacin, etc.; cork extract, licorice extract, Aloe Vera Extract, Brass Extract, Tea Extract, Cucumber Extract, Clove Extract, Astragalus Extract, Witch Hazel Extract, Placenta Extract, Algae Extract, Buckeye Extract, Grapefruit Extract, Luo Hanbai extract, royal jelly extract, eucalyptus extract, Luo Hanbai extract and other animal and plant extracts; potassium hydroxide, sodium hydroxide, triethanolamine, sodium carbonate and other alkali; citric acid, tartaric acid, lactic acid, phosphoric acid, succinic acid, Acid such as adipic acid.

The method for producing an emulsified composition of the present invention is preferably after the step 1 of mixing the aqueous phase I containing the components (A) to (D) and the component (F) (F1) to be emulsified and cooled, and further comprising The step of mixing the aqueous phase component (aqueous phase II) containing the component (E) and the remainder (F2) of the component (F). According to this method, it is preferred that the polymer is allowed to interact after the formation of the α-gel structure, whereby an emulsion excellent in stability over a wide temperature range can be obtained.

Step 1 is a step of forming an α-gel structure, preferably selected from the following four steps of steps 1A, 1B, 1C and 1D. In terms of manufacturability Preferably, it is selected from the group consisting of the steps 1A and 1C including the step of neutralizing the unneutralized component (D) by a base; and from the viewpoint of exhibiting viscosity, it is preferably selected from the component ( D) Mixing into step 1A and step 1B in the oil phase. As described above, step 1 preferably includes one selected from the group consisting of step 1A, step 1B, and step 1C, and more preferably includes step 1A or step 1B, and further preferably includes step 1A.

Step 1A comprises the steps of: obtaining a mixed component of the oil phase containing the components (A), (B), (C) and the unneutralized component (D), and mixing a portion of the component (F) in the oil phase (F1) and the aqueous phase I of the base are emulsified and cooled.

Step 1B includes the steps of: obtaining a mixed component of an oil phase containing a salt of the components (A), (B), (C), and the component (D), and mixing a portion containing the component (F) in the oil phase (F1) The aqueous phase I is emulsified and cooled.

Step 1C includes the steps of: obtaining a mixed component containing the oil phase of the components (A), (B), and (C), and mixing the oil phase with a portion containing the unneutralized component (D) and the component (F) (F1) and the aqueous phase I of the base are emulsified and cooled.

Step 1D includes the steps of: obtaining a mixed component containing the oil phases of the components (A), (B), and (C), and mixing the salt containing the component (D) and one of the components (F) in the oil phase (F1) The aqueous phase I is emulsified and cooled.

In these methods, the component (F) water is divided into (F1) and (F2) for addition and mixing, and the mass ratio thereof is preferably (F1) / (F2) = 0.1 to 9, and further preferably 0.25 to 4. .

The obtained emulsified composition is an α-gel (α-form crystal) which inhibits crystallization (γ Precipitation of type crystal). The α-gel can be confirmed by structural analysis of X-rays. The α-type structure is characterized in that it is a hexagonal crystal system, and the lipophilic group is oriented at a right angle with respect to the surface of the hydrophilic base layer, and a steep diffraction peak appears near the Bragg angle of 21 to 23°.

Moreover, the viscosity of the emulsified composition at 25 ° C is 10 to 8000 dPa. s, more preferably 500~1500 dPa. s, and further preferably 1500~5000 dPa. s. The emulsified composition of the present invention can be obtained by combining the above components with such a high viscosity and elastic liquidity.

Further, in the present invention, the viscosity is measured by a B8R type rotational viscometer (Rotor C or D, 5 r/min, measured for 1 minute) at 25 °C.

Further, the obtained emulsified composition is an oil-in-water emulsion composition, and is suitable, for example, as a cosmetic such as a lotion, an emulsion, a cream, a gel, or an external preparation for skin. In the above embodiment, the emulsified composition of the present invention can be further used as a skin coating agent, a moisture retaining agent for the skin, and a coating film forming agent for the skin.

[Examples] Examples 1 to 10 and Comparative Examples 1 to 7

The oil-in-water emulsion composition of the composition shown in Tables 1 and 2 was produced, and the viscosity and the residual moisture content were measured, and the film was subjected to SAXS (Small-angle X-ray scattering). Confirmation of the sheet-like structure and observation of the surface state by SEM (Scanning Electron Microscope). Further, the persistence of moistness, the touch of the skin after application, and the appearance were evaluated. The results are shown together in Tables 1 and 2.

(Production method)

The components of the first phase were heated and mixed at 80 to 90 ° C, and the components of the second phase heated to 80 to 90 ° C were added thereto under stirring by a propeller (300 rpm), and the mixture was stirred at 7000 rpm for 10 minutes using a homomixer. Under the conditions, emulsification was carried out while applying shear to form an α-gel. After gradually cooling to 25 ° C, the component of the third phase was added to obtain an oily emulsified composition in water.

(evaluation method) (1) Viscosity:

The measurement was carried out at 25 ° C by a B8R type rotational viscometer (Rotor C or D, 5 r/min, measured for 1 minute).

(2) Residual water content:

In a metal tray of 6 × 6 cm, 1 g of the oil-type emulsified composition in water was uniformly spread at a certain thickness, and the mass change was plotted against time at a constant temperature and humidity of 20 ° C and a humidity of 40%. By forming a flaky film over time, the mass change thereafter becomes extremely small. The amount of residual water after 24 hours from which the mass became a constant value was determined, and the amount of moisture in the preparation relative to the solid content was determined according to the following formula. The solid content component contains all components (A) to (E).

(3) Confirmation of the flaky structure of SAXS:

The oil-in-water emulsion composition was uniformly spread at 0.001 g/cm ² on an artificial leather Supplare (registered trademark) and dried for 1 day, and then irradiated for 30 minutes with a Nano-viewer, λCuKα=1.54Å, and a camera length. Under the condition of 649.5 mm, the state of the surface of the film was measured in the range of 2θ=0.2~5°.

(4) Observation of the surface state of the film using SEM:

After the oil-in-water emulsion composition was uniformly spread at 0.001 g/cm ² on an artificial leather Supplare (registered trademark) and dried for 1 day, the surface of the film was observed by SEM (scanning electron microscope) at a magnification of 50 times. State. The results are expressed on the following basis.

○: The boundary between the ridge skin and the groove skin is smooth.

△: The boundary portion of the ridge skin and the groove epidermis is wound up.

×: No film was formed.

(5) Moisture persistence, touch (smoothness) and appearance (smoothness of appearance) of the skin after application:

Let 12 professional functional inspectors apply the "smoothness of the touch of the skin" and the "smoothness of the appearance of the skin" after applying the oil-based emulsified composition of 0.4 to 0.6 g on the face. The "wetness persistence" after 10 hours was evaluated for sensitization. The results are expressed in terms of the number of functional inspectors rated as “good”.

Examples 11 to 29 and Comparative Examples 8 to 9

The oil-in-water emulsion composition of the composition shown in Tables 3 to 6 was produced in the same manner as in Examples 1 to 10, and the viscosity and residual moisture content were measured, and the film was confirmed by the SAXS sheet-like structure. Observe the surface state of the SEM. Moreover, the persistence of moistness, the touch of the skin after application, and the appearance were evaluated. The results are shown together in Tables 3 to 6.

Example 1, 30~32

The oil-in-water emulsion composition of the composition shown in Table 7 was produced in the same manner as in Examples 1 to 10, and the viscosity and residual moisture content were measured, and the film was confirmed to have a sheet-like structure using SAXS and EM was used. Observation of the surface state. Moreover, the persistence of moistness, the touch of the skin after application, and the appearance were evaluated. The results are shown together in Table 7.

Examples 1 and 30 were produced by the manufacturing step 1A, Example 31 was produced by the manufacturing step 1C, and Example 32 was produced by the manufacturing step 1D. By disposing the unneutralized component (D) in the oil phase, the following results were obtained by the production of Example 1 and Example 30 produced in the step 1A: the smoothness of the touch of the skin after application was evaluated, and the cerebral palsy was high. The precipitation of the crystal of the amine is suppressed, and the flaky structure is confirmed, the moisturizing effect is high, and a high viscosity is obtained.

Claims (10)

A method for producing an emulsified composition, comprising the step 2 after the step 1, and forming an α-gel structure, the step 1 comprising the following components (A), (B), (C), (D) and (F1) The aqueous phase I is mixed, emulsified and cooled: (A) glycerin fatty acid ester or glycerol monoalkyl ether 0.001 to 10% by mass, (B) selected from higher alcohols and sterols having a carbon number of 14 to 22 0.001 to 10% by mass of one or more kinds of compounds, and 0.001 to 15% by mass of the compound represented by the formula (3) or the formula (4) (wherein R ¹¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 7 to 19 carbon atoms which may be substituted by a hydroxyl group; Z ₁ represents a methylene group or a methine group; X ⁵ and X ⁶ and X ⁷ each independently represents a hydrogen atom, a hydroxyl group or an ethyloxy group; X ⁸ represents a hydrogen atom or forms a pendant oxy group together with an adjacent oxygen atom (however, when Z ₁ is a methine group, X ⁵ and X ^{6 are used} ) when one of them is a hydrogen atom, the other is not present, X ⁸ forming the side group, X ⁷ does not exist); R ¹² represents a hydroxyl group or acetyl oxymethyl; R ¹³ represents a hydrogen atom, or a C 1 Alkyl group of ~4; R ¹⁴ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 30 carbon atoms which may be substituted by a hydroxyl group, or may be represented by an ω terminal ester bond of the alkyl group. a hydroxy group substituted with a linear or branched saturated or unsaturated fatty acid having a carbon number of 8 to 22; a dotted line indicating an unsaturated bond) (wherein R ¹⁵ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom which may be substituted with a hydroxyl group and has a carbon number of 10 to 22; X ⁹ represents a hydrogen atom, an ethyl fluorenyl group or a glyceryl group; ¹⁶ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 22 carbon atoms which may be substituted by a hydroxyl group or an amine group, or a carbon number which may be substituted by a hydroxyl group at the ω terminal ester of the hydrocarbon group a linear or branched saturated or unsaturated fatty acid of 8 to 22; R ¹⁷ represents a hydrogen atom, or represents a total carbon number of 1 to 30 which may be substituted by a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an ethoxy group. Alkyl), (D) anionic surfactant 0.00025 to 10% by mass, (F1) water; Step 2 is further mixed with an aqueous phase II containing: (E) selected from alkyl-modified polyacrylic ethylene polymerization And the water-soluble polymer in the alkyl-modified polysaccharide-based polymer is 0.001 to 6% by mass, and (F2) water. The method for producing an emulsified composition according to claim 1, wherein the step 1 is the step 1A or the step 1B, and the step 1A comprises the step of obtaining the component (A), (B), (C) and the unneutralized component (D). a mixed component of the oil phase, and an aqueous phase I containing (F1) and a base mixed in the oil phase to be emulsified and cooled; the step 1B includes the following steps: obtaining the component (A), (B), C) and a mixed component of the oil phase of the salt of the component (D), and the aqueous phase I containing (F1) is mixed in the oil phase to be emulsified and cooled. The method for producing an emulsified composition according to claim 1, wherein the step 1 is the step 1C or the step 1D, and the step 1C comprises the steps of: obtaining a mixed component containing the oil phase of the components (A), (B) and (C), and The aqueous phase is mixed with the aqueous phase I containing the unneutralized components (D), (F1) and alkali to be emulsified and cooled; the step 1D includes the following steps: obtaining the components (A), (B) and The mixed component of the oil phase of C), and the salt phase containing the component (D) and the aqueous phase I of (F1) are mixed in the oil phase to be emulsified and cooled. The method for producing an emulsified composition according to claim 1, wherein the mass ratio of the components (A), (B), (C), (D) and (E) is (E) / ((A) + (B) + (C)) = 0.0025 to 50, and (E) / (D) = 0.025 to 100. The method for producing an emulsified composition according to claim 1, wherein the component (D) is a fatty acid salt selected from the group consisting of carbon atoms 12 to 24, an alkyl sulfate salt, an alkyl ether sulfate, a fatty acid decyl sulfonate, and an alkyl group. Among phosphates, polyoxyethylene alkyl ether phosphates and long chain N-mercapto glutamate. The method for producing an emulsified composition according to claim 1, wherein the emulsified composition has a viscosity of from 10 to 8000 dPas at 25 °C. The method for producing an emulsified composition according to claim 1, wherein the emulsified composition contains the component (A) 0.05 to 7 mass%, the component (B) 0.05 to 7 mass%, the component (C) 0.05 to 7 mass%, and the component ( D) 0.05 to 2% by mass, and component (E) 0.05 to 5% by mass. The method for producing an emulsified composition according to claim 1, wherein the mass ratio of the components (A), (B), (C), (D) and (E) is (E) / ((A) + (B) + (C)) = 0.01~3. The method for producing an emulsified composition according to claim 1, wherein the α -gel structure is formed by the step 1. The method for producing an emulsified composition according to claim 2, wherein the base contained in the aqueous phase I is one or two selected from the group consisting of arginine and sodium hydroxide.