JP2020200283A - Sheet-like cosmetics - Google Patents
Sheet-like cosmetics Download PDFInfo
- Publication number
- JP2020200283A JP2020200283A JP2019109083A JP2019109083A JP2020200283A JP 2020200283 A JP2020200283 A JP 2020200283A JP 2019109083 A JP2019109083 A JP 2019109083A JP 2019109083 A JP2019109083 A JP 2019109083A JP 2020200283 A JP2020200283 A JP 2020200283A
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- Prior art keywords
- group
- gel
- hydrogen atom
- sheet
- containing composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000002537 cosmetic Substances 0.000 title claims abstract description 24
- 239000000203 mixture Substances 0.000 claims abstract description 58
- 239000000463 material Substances 0.000 claims abstract description 22
- -1 fatty acid ester Chemical class 0.000 claims description 90
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 61
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 52
- 125000004432 carbon atom Chemical group C* 0.000 claims description 48
- 125000001183 hydrocarbyl group Chemical group 0.000 claims description 33
- 229920006395 saturated elastomer Polymers 0.000 claims description 27
- 239000002253 acid Substances 0.000 claims description 26
- 150000001875 compounds Chemical class 0.000 claims description 25
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- 125000005113 hydroxyalkoxy group Chemical group 0.000 claims description 19
- 125000004122 cyclic group Chemical group 0.000 claims description 18
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- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 claims description 17
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- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 5
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- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 229940073665 octyldodecyl myristate Drugs 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- NPKKRSHVJIQBKU-UHFFFAOYSA-N ornogenin Natural products CC(OC(=O)C=Cc1ccccc1)C2(O)CCC3(O)C4(O)CC=C5CC(O)CCC5(C)C4CC(OC(=O)C=Cc6ccccc6)C23C NPKKRSHVJIQBKU-UHFFFAOYSA-N 0.000 description 1
- 239000010702 perfluoropolyether Substances 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 229940068065 phytosterols Drugs 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 235000002378 plant sterols Nutrition 0.000 description 1
- 229920001707 polybutylene terephthalate Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 1
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- ONQDVAFWWYYXHM-UHFFFAOYSA-M potassium lauryl sulfate Chemical compound [K+].CCCCCCCCCCCCOS([O-])(=O)=O ONQDVAFWWYYXHM-UHFFFAOYSA-M 0.000 description 1
- 229940116985 potassium lauryl sulfate Drugs 0.000 description 1
- MQOCIYICOGDBSG-UHFFFAOYSA-M potassium;hexadecanoate Chemical compound [K+].CCCCCCCCCCCCCCCC([O-])=O MQOCIYICOGDBSG-UHFFFAOYSA-M 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000002964 rayon Substances 0.000 description 1
- 229940109850 royal jelly Drugs 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 150000003335 secondary amines Chemical class 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
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- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- BTURAGWYSMTVOW-UHFFFAOYSA-M sodium dodecanoate Chemical compound [Na+].CCCCCCCCCCCC([O-])=O BTURAGWYSMTVOW-UHFFFAOYSA-M 0.000 description 1
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- 229940082004 sodium laurate Drugs 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- ZNYIJXQYUNSKDX-NTISSMGPSA-M sodium;hydron;(2s)-2-(tetradecanoylamino)pentanedioate Chemical compound [Na+].CCCCCCCCCCCCCC(=O)N[C@H](C([O-])=O)CCC(O)=O ZNYIJXQYUNSKDX-NTISSMGPSA-M 0.000 description 1
- 239000001587 sorbitan monostearate Substances 0.000 description 1
- 235000011076 sorbitan monostearate Nutrition 0.000 description 1
- 229940035048 sorbitan monostearate Drugs 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229940071136 stearoyl glutamate Drugs 0.000 description 1
- 229940012831 stearyl alcohol Drugs 0.000 description 1
- 229940032091 stigmasterol Drugs 0.000 description 1
- HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 description 1
- 235000016831 stigmasterol Nutrition 0.000 description 1
- BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000012916 structural analysis Methods 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 125000002469 tricosyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
Description
本発明は、シート状化粧料に関する。 The present invention relates to sheet-shaped cosmetics.
αゲルは、水和型の結晶構造であり、ラメラ構造を有する。皮膚最外層の角層に存在する角層細胞間脂質も、その大半がこのαゲル構造をとっている。そして、皮膚に対して、外部からの物質の侵入、内部からの水分蒸散を抑制すると同時に、そのもの自身が水分を保持することで、皮膚の柔軟性やなめらかな外観を保つ機能を有している。皮膚中において、角層は、水分を結合水の形で約３３％保持しており、角層細胞間脂質は、うち約１３％の結合水（ここで、結合水とは、構成分子に束縛された水と定義する）を保持していることが報告されている（非特許文献１）。
例えば、特許文献１には、セラミド類等を含有する乳化組成物が、αゲル構造を形成し、保湿性が高いことが記載されている。このようなαゲル含有組成物で皮膚表面を覆った場合、角層細胞間脂質と同様、乾燥時において、水分を多く含有でき、潤い感を持続できることが期待される。
The α-gel has a hydrated crystal structure and has a lamellar structure. Most of the intercellular lipids in the stratum corneum, which are present in the outermost stratum corneum of the skin, also have this α-gel structure. It also has the function of suppressing the invasion of substances from the outside and the evaporation of water from the inside of the skin, and at the same time, by retaining the water itself, it maintains the flexibility and smooth appearance of the skin. .. In the skin, the stratum corneum retains about 33% of water in the form of bound water, and the intercellular lipids of the stratum corneum are about 13% of bound water (where bound water is bound to constituent molecules. It has been reported that it retains water (defined as water) (Non-Patent Document 1).
For example, Patent Document 1 describes that an emulsified composition containing ceramides and the like forms an α-gel structure and has high moisturizing properties. When the skin surface is covered with such an α-gel-containing composition, it is expected that a large amount of water can be contained at the time of drying and a moisturizing feeling can be maintained, similar to the intercellular lipids in the stratum corneum.
しかしながらαゲル含有組成物は、水分保持能が期待される一方で、αゲルを構成する固体脂成分の使用感が重く、水分保持能をより高めるために、αゲル構成成分を単に増量したのでは、べたつき感がでてしまい、肌になじませるまでに長時間を要するなど、良好な使用感及び使用性を得ることができない。また、αゲル含有組成物を塗布した後にファンデーション等のメイクアップ化粧料を塗布しようとした場合、粉体を均一に付着させることができないという課題があった。
従って、本発明の課題は、αゲル含有組成物を塗布する際の使用感及び使用性を向上させ、αゲル含有組成物を塗布した後にファンデーション等のメイクアップ化粧料を塗布した場合に、粉体を均一に付着させることができる化粧料及び化粧方法を提供することにある。
However, while the α-gel-containing composition is expected to have a water-retaining ability, the solid fat component constituting the α-gel has a heavy usability, and the amount of the α-gel component is simply increased in order to further enhance the water-retaining ability. In this case, a sticky feeling is produced, and it takes a long time to be applied to the skin, so that a good usability and usability cannot be obtained. Further, when an attempt is made to apply a make-up cosmetic such as a foundation after applying the α-gel-containing composition, there is a problem that the powder cannot be uniformly adhered.
Therefore, an object of the present invention is to improve the usability and usability when applying the α-gel-containing composition, and when a make-up cosmetic such as foundation is applied after applying the α-gel-containing composition, the powder is used. It is an object of the present invention to provide a cosmetic and a makeup method capable of uniformly adhering the body.
そこで本発明者は、αゲル含有組成物の肌への適用方法について検討してきたところ、αゲル含有組成物をシート基材に含侵させ肌に貼付することにより、多量のαゲルを肌上にべたつくことなく残留させ、かつその後にファンデーションを塗布した場合でも、粉体を均一に付着させることができることを見出し、本発明を完成した。 Therefore, the present inventor has studied a method for applying the α-gel-containing composition to the skin. By impregnating the α-gel-containing composition on the sheet substrate and attaching the α-gel-containing composition to the skin, a large amount of α-gel can be applied onto the skin. The present invention has been completed by finding that the powder can be uniformly adhered even when the powder is left without stickiness and the foundation is applied thereafter.
すなわち、本発明は、αゲル含有組成物をシート基材に含浸させたシート状化粧料を提供するものである。 That is, the present invention provides a sheet-like cosmetic in which a sheet base material is impregnated with an α-gel-containing composition.
本発明のシート状化粧料によれば、多量のαゲルを肌上にべたつくことなく残留させ、かつその後にファンデーションを塗布した場合でも、粉体を均一に付着させることができるという効果が得られる。 According to the sheet-shaped cosmetic of the present invention, it is possible to obtain an effect that a large amount of α-gel remains on the skin without stickiness, and even when a foundation is applied thereafter, the powder can be uniformly adhered. ..
本発明のシート状化粧料は、αゲル含有組成物をシート基材に含浸させたものである。 The sheet-shaped cosmetic of the present invention is obtained by impregnating a sheet base material with an α-gel-containing composition.
本発明に用いられるαゲル含有組成物としては、固体脂成分を含有しているものが好ましく、水分保持能の高さの点から、その中でもセラミド類を含有しているものがより好ましい。 As the α-gel-containing composition used in the present invention, one containing a solid fat component is preferable, and one containing ceramides is more preferable from the viewpoint of high water retention ability.
本発明に用いられるαゲル含有組成物は、次の成分（Ａ）、（Ｂ）及び（Ｃ）を含有するものが更に好ましい。
（Ａ）グリセリンモノ脂肪酸エステル、ソルビタンモノ脂肪酸エステル、ソルビタンジ脂肪酸エステル、ソルビトールモノ脂肪酸エステル、ソルビトールジ脂肪酸エステル、ショ糖モノ脂肪酸エステル、及びグリセリンモノアルキルエーテルから選ばれる１種以上の化合物
（Ｂ）炭素数１４〜２２の高級アルコール、及びステロール類から選ばれる１種以上の化合物
（Ｃ）一般式（１）：
The α-gel-containing composition used in the present invention is more preferably one containing the following components (A), (B) and (C).
(A) One or more compounds selected from glycerin monofatty acid ester, sorbitan monofatty acid ester, sorbitandi fatty acid ester, sorbitol monofatty acid ester, sorbitol difatty acid ester, sucrose monofatty acid ester, and glycerin monoalkyl ether (B) One or more compounds selected from higher alcohols having 14 to 22 carbon atoms and sterols (C) General formula (1):
（式中、Ｒ1はヒドロキシル基、カルボニル基若しくはアミノ基が置換していてもよい、炭素数４〜３０の直鎖、分岐鎖若しくは環状の飽和若しくは不飽和の炭化水素基を示し；Ｚはメチレン基、メチン基又は酸素原子を示し；Ｘ1、Ｘ2及びＸ3は各々独立して水素原子、ヒドロキシル基又はアセトキシ基を示し、Ｘ4は水素原子、アセチル基又はグリセリル基を示すか、隣接する酸素原子と一緒になってオキソ基を形成し（但し、Ｚがメチン基のとき、Ｘ1とＸ2のいずれか一方が水素原子であり、他方は存在しない。Ｘ4がオキソ基を形成するとき、Ｘ3は存在しない。）；Ｒ2及びＲ3は各々独立して水素原子、ヒドロキシル基、ヒドロキシメチル基又はアセトキシメチル基を示し；Ｒ4はヒドロキシル基、カルボニル基又はアミノ基が置換していてもよい、主鎖にエーテル結合、エステル結合又はアミド結合を有していてもよい炭素数５〜６０の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基を示し；Ｒ5は水素原子を示すか、ヒドロキシル基、ヒドロキシアルコキシ基、アルコキシ基及びアセトキシ基から選ばれる置換基を有していてもよい、総炭素数１〜３０の直鎖又は分岐鎖の飽和又は不飽和の炭化水素基を示し；破線部は不飽和結合であってもよいことを示す）で表される化合物 (In the formula, R 1 represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 4 to 30 carbon atoms, which may be substituted with a hydroxyl group, a carbonyl group or an amino group; Z is Indicates a methylene group, a methine group or an oxygen atom; X 1 , X 2 and X 3 independently represent a hydrogen atom, a hydroxyl group or an acetoxy group, and X 4 represents a hydrogen atom, an acetyl group or a glyceryl group. Together with adjacent oxygen atoms form an oxo group (however, when Z is a methine group, one of X 1 and X 2 is a hydrogen atom and the other does not exist. X 4 is an oxo group. When formed, X 3 is absent.); R 2 and R 3 each independently represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an acetoxymethyl group; R 4 has a hydroxyl group, a carbonyl group or an amino group. Shows a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 60 carbon atoms, which may be substituted and may have an ether bond, an ester bond or an amide bond in the main chain; R 5 represents a hydrogen atom or may have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group, and is saturated or unsaturated in a linear or branched chain having a total carbon number of 1 to 30. A compound represented by (indicating a saturated hydrocarbon group; the dashed part indicates that it may be an unsaturated bond).
［成分（Ａ）］
本発明で用いる成分（Ａ）は、グリセリンモノ脂肪酸エステル、ソルビタンモノ脂肪酸エステル、ソルビタンジ脂肪酸エステル、ソルビトールモノ脂肪酸エステル、ソルビトールジ脂肪酸エステル、ショ糖モノ脂肪酸エステル、グリセリンモノアルキルエーテルから選ばれる１種以上の化合物であり、炭素数１０〜２４の脂肪酸残基又はアルキル基を有するものである。ラメラ状の皮膜の形成性、水分保持能が向上する観点から、グリセリンモノ脂肪酸エステル、グリセリンモノアルキルエーテル、ソルビタンモノ脂肪酸エステル及びソルビタンジ脂肪酸エステルが好ましく、モノパルミチン酸グリセリル、モノステアリン酸グリセリル、モノベヘン酸グリセリル、モノセチルグリセリルエーテル、モノステアリルグリセリルエーテル、モノステアリン酸ソルビタン、ジステアリン酸ソルビタンがより好ましく、モノベヘン酸グリセリル、ジステアリン酸ソルビタンが更に好ましい。
[Component (A)]
The component (A) used in the present invention is one selected from glycerin monofatty acid ester, sorbitan monofatty acid ester, sorbitandi fatty acid ester, sorbitol monofatty acid ester, sorbitol difatty acid ester, sucrose monofatty acid ester, and glycerin monoalkyl ether. It is the above-mentioned compound and has a fatty acid residue or an alkyl group having 10 to 24 carbon atoms. From the viewpoint of improving the formability of the lamellar film and the water retention capacity, glycerin monofatty acid ester, glycerin monoalkyl ether, sorbitan monofatty acid ester and sorbitan difatty acid ester are preferable, and glyceryl monopalmitate, glyceryl monostearate, and monobehen Glyceryl acid acid, monocetyl glyceryl ether, monostearyl glyceryl ether, sorbitan monostearate, and sorbitan distearate are more preferable, and glyceryl monobehate and sorbitan distearate are even more preferable.
成分（Ａ）は、１種以上を用いることができ、αゲル含有組成物中に０．００１〜１０質量％含有され、好ましくは０．０５〜７質量％、更に０．１〜３質量％含有されるのが、水分保持能が高まるのでより好ましい。 One or more kinds of the component (A) can be used, and 0.001 to 10% by mass is contained in the α-gel-containing composition, preferably 0.05 to 7% by mass, and further 0.1 to 3% by mass. It is more preferable that it is contained because the water retention ability is enhanced.
［成分（Ｂ）］
本発明で用いる成分（Ｂ）は、炭素数１４〜２２の高級アルコール、ステロール類から選ばれる１種以上の化合物である。
[Component (B)]
The component (B) used in the present invention is one or more compounds selected from higher alcohols and sterols having 14 to 22 carbon atoms.
高級アルコールは、炭素数１４〜２２、より好ましくは炭素数１６〜１８のもので、例えば、ミリスチルアルコール、セタノール、ステアリルアルコール、ベヘニルアルコール、オレイルアルコール等が挙げられる。
これらのうち、直鎖アルキル基を有するものが好ましく、更に、セタノール、ステアリルアルコールが好ましく、セタノールがより好ましい。
The higher alcohol has 14 to 22 carbon atoms, more preferably 16 to 18 carbon atoms, and examples thereof include myristyl alcohol, cetanol, stearyl alcohol, behenyl alcohol, and oleyl alcohol.
Of these, those having a linear alkyl group are preferable, cetanol and stearyl alcohol are preferable, and cetanol is more preferable.
また、ステロール類としては、コレステロール及びフィトステロールが挙げられる。フィトステロールは、β−シトステロール、カンペステロール、スティグマステロール、ブラシカステロール等の植物ステロールの総称であり、その組成は限定されるものではない。 Examples of sterols include cholesterol and phytosterols. Phytosterol is a general term for plant sterols such as β-sitosterol, campesterol, stigma sterol, and brassicasterol, and its composition is not limited.
成分（Ｂ）は、１種以上を用いることができ、αゲル含有組成物中に０．００１〜１０質量％含有され、好ましくは０．０５〜７質量％、更に０．１〜３質量％含有されるのが、水分保持能が高まるのでより好ましい。 One or more kinds of the component (B) can be used, and 0.001 to 10% by mass is contained in the α-gel-containing composition, preferably 0.05 to 7% by mass, and further 0.1 to 3% by mass. It is more preferable that it is contained because the water retention ability is enhanced.
［成分（Ｃ）］
本発明で用いる成分（Ｃ）は、前記一般式（１）で表わされる化合物である。
[Component (C)]
The component (C) used in the present invention is a compound represented by the general formula (1).
式中、Ｒ1は、ヒドロキシル基、カルボニル基若しくはアミノ基が置換していてもよい、炭素数４〜３０の、好ましくはヒドロキシル基が置換していてもよい炭素数７〜２２の直鎖、分岐鎖若しくは環状の飽和若しくは不飽和の炭化水素基又は水素原子である。
Ｚはメチレン基、メチン基又は酸素原子のいずれかを示す。
In the formula, R 1 is a straight chain having 4 to 30 carbon atoms, preferably 7 to 22 carbon atoms which may be substituted with a hydroxyl group, a carbonyl group or an amino group. A branched or cyclic saturated or unsaturated hydrocarbon group or hydrogen atom.
Z represents either a methylene group, a methine group or an oxygen atom.
Ｘ1、Ｘ2及びＸ3は、各々独立して水素原子、ヒドロキシル基又はアセトキシ基を示す。Ｘ1、Ｘ2及びＸ3のうち０〜１個がヒドロキシル基で、残余が水素原子であるのが好ましい。Ｚがメチン基のとき、Ｘ1とＸ2のいずれか一方のみが水素原子であり、他方は存在しない。また、Ｘ4は水素原子かグリセリル基であるのが好ましい。
Ｒ2及びＲ3は、水素原子、ヒドロキシル基、ヒドロキシメチル基又はアセトキシメチル基を示し、好ましいＲ2は水素原子又はヒドロキシメチル基であり、好ましいＲ3は水素原子である。
X 1 , X 2 and X 3 each independently represent a hydrogen atom, a hydroxyl group or an acetoxy group. It is preferable that 0 to 1 of X 1 , X 2 and X 3 are hydroxyl groups and the remainder is a hydrogen atom. When Z is a methine group, only one of X 1 and X 2 is a hydrogen atom and the other does not exist. Further, X 4 is preferably a hydrogen atom or a glyceryl group.
R 2 and R 3 represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an acetoxymethyl group, preferably R 2 is a hydrogen atom or a hydroxymethyl group, and preferred R 3 is a hydrogen atom.
Ｒ4は、ヒドロキシル基、カルボキシ基又はアミノ基が置換していてもよい、主鎖にエーテル結合、エステル結合又はアミド結合を有していてもよい炭素数５〜６０の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基を示す。好ましくは、ヒドロキシル基又はアミノ基が置換していてもよい炭素数５〜３５の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基、又は該炭化水素基のω位に、ヒドロキシル基が置換してもよい炭素数８〜２２の直鎖、分岐又は環状の飽和又は不飽和の脂肪酸がエステル結合又はアミド結合したものが挙げられる。結合する脂肪酸としては、イソステアリン酸、１２−ヒドロキシステアリン酸又はリノール酸が好ましい。 R 4 may have an ether bond, an ester bond or an amide bond in the main chain, which may be substituted with a hydroxyl group, a carboxy group or an amino group, and is a linear, branched chain or a branched chain having 5 to 60 carbon atoms. Indicates a cyclic saturated or unsaturated hydrocarbon group. Preferably, a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 35 carbon atoms, which may be substituted with a hydroxyl group or an amino group, or a hydroxyl group at the ω position of the hydrocarbon group. Examples thereof include those in which linear, branched or cyclic saturated or unsaturated fatty acids having 8 to 22 carbon atoms which may be substituted are ester-bonded or amide-bonded. As the fatty acid to be bound, isostearic acid, 12-hydroxystearic acid or linoleic acid is preferable.
Ｒ5は、水素原子を示すか、ヒドロキシル基、ヒドロキシアルコキシ基、アルコキシ基及びアセトキシ基から選ばれる置換基を有していてもよい総炭素数１〜３０の直鎖又は分岐鎖の飽和又は不飽和の炭化水素基である。Ｒ1が水素原子、Ｚが酸素原子のときＲ5は総炭素数１０〜３０の炭化水素基である。また、Ｒ1が炭化水素基のときＲ5は総炭素数１〜８の炭化水素基である。これらのうち、水素原子あるいは、ヒドロキシル基及びヒドロキシアルコキシ基、アルコキシ基から選ばれる１〜３個が置換していてもよい総炭素数１〜８の炭化水素基が好ましい。ここで、ヒドロキシアルコキシ基及びアルコキシ基としては炭素数１〜７のものが好ましい。 R 5 represents a hydrogen atom or may have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group. Saturation or non-saturation of a linear or branched chain having 1 to 30 total carbon atoms. It is a saturated hydrocarbon group. When R 1 is a hydrogen atom and Z is an oxygen atom, R 5 is a hydrocarbon group having a total carbon number of 10 to 30. Further, when R 1 is a hydrocarbon group, R 5 is a hydrocarbon group having a total carbon number of 1 to 8. Of these, a hydrogen atom or a hydrocarbon group having 1 to 8 total carbon atoms, which may be substituted with 1 to 3 selected from a hydroxyl group, a hydroxyalkoxy group, and an alkoxy group, is preferable. Here, the hydroxyalkoxy group and the alkoxy group preferably have 1 to 7 carbon atoms.
一般式（１）で表わされる化合物としては、次の一般式（２）又は（３）で表わされるセラミド類が好ましい。
（Ｉ）一般式（２）で表わされる化合物は、天然由来のセラミド類又は同構造の合成物であっても良い。
As the compound represented by the general formula (1), ceramides represented by the following general formula (2) or (3) are preferable.
(I) The compound represented by the general formula (2) may be naturally occurring ceramides or a compound having the same structure.
（式中、Ｒ11はヒドロキシル基が置換していてもよい炭素数７〜１９の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基を示し；Ｚ1はメチレン基又はメチン基を示し；Ｘ5、Ｘ6、及びＸ7は各々独立して水素原子、ヒドロキシル基又はアセトキシ基を示し；Ｘ8は水素原子を示すか、隣接する酸素原子と一緒になってオキソ基を形成し（但し、Ｚ1がメチン基のとき、Ｘ5とＸ6のいずれか一方が水素原子であり、他方は存在しない。Ｘ8がオキソ基を形成するとき、Ｘ7は存在しない。）；Ｒ12はヒドロキシメチル基又はアセトキシメチル基を示し；Ｒ13は水素原子を示すか、炭素数１〜４のアルキル基を示し；Ｒ14はヒドロキシル基が置換していてもよい炭素数５〜３０の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基であるか、又は該アルキル基のω末端に、ヒドロキシル基が置換していてもよい炭素数８〜２２の直鎖又は分岐鎖の飽和又は不飽和の脂肪酸がエステル結合したものを示し；破線部は不飽和結合であってもよいことを示す。） (In the formula, R 11 represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 7 to 19 carbon atoms in which the hydroxyl group may be substituted; Z 1 represents a methylene group or a methine group. Shown; X 5 , X 6 and X 7 each independently represent a hydrogen atom, a hydroxyl group or an acetoxy group; X 8 represents a hydrogen atom or together with adjacent oxygen atoms to form an oxo group. (However, when Z 1 is a methine group, one of X 5 and X 6 is a hydrogen atom and the other does not exist. When X 8 forms an oxo group, X 7 does not exist.); R 12 indicates a hydroxymethyl group or an acetoxymethyl group; R 13 indicates a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; R 14 indicates an alkyl group having 5 to 30 carbon atoms which may be substituted with a hydroxyl group. A linear, branched or cyclic saturated or unsaturated hydrocarbon group, or a linear or branched chain having 8 to 22 carbon atoms in which a hydroxyl group may be substituted at the ω end of the alkyl group. Indicates that saturated or unsaturated fatty acids are ester-bonded; the dashed line indicates that the unsaturated bond may be used.)
好ましくは、Ｒ11が炭素数７〜１９、更に好ましくは炭素数１３〜１５の直鎖アルキル基；Ｒ14がヒドロキシル基が置換しても良い炭素数９〜２７の直鎖アルキル基又はリノール酸がエステル結合した炭素数９〜２７の直鎖アルキル基である化合物が挙げられる。また、Ｘ8は水素原子を示すか、酸素原子とともにオキソ基を形成するのが好ましい。更に、Ｒ14としては、トリコシル、１−ヒドロキシペンタデシル、１−ヒドロキシトリコシル、ヘプタデシル、１−ヒドロキシウンデシル、ω位にリノール酸がエステル結合したノナコシル基が好ましい。 Preferably, R 11 is a linear alkyl group having 7 to 19 carbon atoms, more preferably 13 to 15 carbon atoms; R 14 is a linear alkyl group having 9 to 27 carbon atoms or a linoleic acid in which the hydroxyl group may be substituted. Examples thereof include compounds which are linear alkyl groups having 9 to 27 carbon atoms in which is ester-bonded. Further, it is preferable that X 8 represents a hydrogen atom or forms an oxo group together with an oxygen atom. Further, as R 14 , tricosyl, 1-hydroxypentadecyl, 1-hydroxytricosyl, heptadecyl, 1-hydroxyundecyl, and a nonacosyl group in which linoleic acid is ester-bonded at the ω position are preferable.
天然型セラミドの具体的な例示として、スフィンゴシン、ジヒドロスフィンゴシン、フィトスフィンゴシン又はスフィンガジエニンがアミド化されたセラミドType１〜７（例えば、J. Lipid Res., 24：759(1983)の図２、及びJ. Lipid. Res.,35：2069(1994)の図４記載のブタ及びヒトのセラミド類）が挙げられる。 As a specific example of the natural ceramide, ceramides Type 1 to 7 in which sphingosine, dihydrosphingosine, phytosphingosine or sphingadienin are amidated (for example, J. Lipid Res., 24: 759 (1983)), FIG. And J. Lipid. Res., 35: 2069 (1994), FIG. 4 ceramides of pigs and humans).
更にこれらのＮ−アルキル体（例えばＮ−メチル体）も含まれる。
これらのセラミドは天然型（Ｄ（−）体）の光学活性体を用いても、非天然型（Ｌ（＋）体）の光学活性体を用いても、更に天然型と非天然型の混合物を用いてもよい。上記化合物の相対立体配置は、天然型の立体配置のものでも、それ以外の非天然型の立体配置のものでも良く、また、これらの混合物によるものでもよい。これらのうち、CERAMIDE1、CERAMIDE2、CERAMIDE3、CERAMIDE5、CERAMIDE6IIの化合物(以上、INCI、8th Edition)及び次式で表わされるものが好ましい。
Further, these N-alkyl compounds (for example, N-methyl compounds) are also included.
These ceramides can be a mixture of natural and non-natural types, whether they use natural (D (-)) optically active substances or non-natural (L (+)) optically active substances. May be used. The relative configuration of the compound may be a natural configuration, a non-natural configuration other than that, or a mixture thereof. Of these, compounds of CERAMIDE1, CERAMIDE2, CERAMIDE3, CERAMIDE5, CERAMIDE6II (above, INCI, 8th Edition) and those represented by the following formulas are preferable.
これらは天然からの抽出物及び合成物のいずれでもよく、市販のものを用いることができる。
このような天然型セラミドの市販のものとしては、Ceramide I、Ceramide III、Ceramide IIIＡ、Ceramide IIIＢ、Ceramide IIIＣ、Ceramide VI（以上、コスモファーム社）、Ceramide TIC-001（高砂香料社）、CERAMIDE II（Quest International社）、DS-Ceramide VI、DS-CLA-Phytoceramide、Ｃ6-Phytoceramide、DS-ceramide Y3S（DOOSAN社）、CERAMIDE２(セダーマ社)が挙げられる。
These may be either natural extracts or synthetics, and commercially available ones can be used.
Commercially available such natural ceramides include Ceramide I, Ceramide III, Ceramide IIIA, Ceramide IIIB, Ceramide IIIC, Ceramide VI (Cosmo Farm), Ceramide TIC-001 (Takasago Fragrance), and CERAMIDE II. (Quest International), DS-Ceramide VI, DS-CLA-Phytoceramide, C6-Phytoceramide, DS-ceramide Y3S (DOOSAN), CERAMIDE2 (Sederma).
（II）一般式（３）で表わされる擬似型セラミド。 (II) Pseudo-type ceramide represented by the general formula (3).
（式中、Ｒ15は、ヒドロキシル基が置換していてもよい炭素数１０〜２２の直鎖、分岐鎖若しくは環状の飽和若しくは不飽和の炭化水素基又は水素原子を示し；Ｘ9は水素原子、アセチル基又はグリセリル基を示し；Ｒ16はヒドロキシル基又はアミノ基が置換していてもよい炭素数５〜２２の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基であるか、又は該炭化水素基のω末端に、ヒドロキシル基が置換していてもよい炭素数８〜２２の直鎖又は分岐鎖の飽和又は不飽和の脂肪酸がエステル結合したものを示し；Ｒ17は水素原子を示すか、ヒドロキシル基、ヒドロキシアルコキシ基、アルコキシ基又はアセトキシ基が置換していてもよい総炭素数１〜３０のアルキル基を示す。） (In the formula, R 15 represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group or hydrogen atom having 10 to 22 carbon atoms in which the hydroxyl group may be substituted; X 9 is a hydrogen atom. , An acetyl group or a glyceryl group; R 16 is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 22 carbon atoms which may be substituted with a hydroxyl group or an amino group. Alternatively, a linear or branched saturated or unsaturated fatty acid having 8 to 22 carbon atoms, which may be substituted with a hydroxyl group, is ester-bonded to the ω end of the hydrocarbon group; R 17 is a hydrogen atom. Or an alkyl group having a total carbon number of 1 to 30 which may be substituted with a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an acetoxy group.)
Ｒ16としては、ノニル、トリデシル、ペンタデシル、ω位にリノール酸がエステル結合したウンデシル基、ω位にリノール酸がエステル結合したペンタデシル基、ω位に１２−ヒドロキシステアリン酸がエステル結合したペンタデシル基、ω位にメチル分岐イソステアリン酸がアミド結合したウンデシル基が好ましい。 R 16 includes nonyl, tridecyl, pentadecyl, an undecyl group in which linoleic acid is ester-bonded at the ω position, a pentadecyl group in which linoleic acid is ester-bonded at the ω position, and a pentadecyl group in which 12-hydroxystearic acid is ester-bonded at the ω position. An undecyl group in which methyl branched isostearic acid is amide-bonded at the ω position is preferable.
Ｒ17は、Ｒ15が水素原子の場合は、ヒドロキシル基、ヒドロキシアルコキシ基、アルコキシ基又はアセトキシ基が置換していてもよい総炭素数１０〜３０の、好ましくは総炭素数１２〜２０のアルキル基であり、Ｒ15がヒドロキシル基が置換していてもよい炭素数１０〜２２の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基である場合には、水素原子を示すか、ヒドロキシル基、ヒドロキシアルコキシ基、アルコキシ基又はアセトキシ基が置換していてもよい総炭素数１〜８のアルキル基を示すものが好ましい。Ｒ17のヒドロキシアルコキシ基又はアルコキシ基としては炭素数１〜７のものが好ましい。 When R 15 is a hydrogen atom, R 17 is an alkyl having a total carbon number of 10 to 30, preferably a total carbon number of 12 to 20, which may be substituted with a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an acetoxy group. If it is a group and R 15 is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 10 to 22 carbon atoms in which the hydroxyl group may be substituted, it indicates a hydrogen atom or indicates a hydrogen atom. Those showing an alkyl group having a total carbon number of 1 to 8 which may be substituted with a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an acetoxy group are preferable. The hydroxyalkoxy group or alkoxy group of R 17 preferably has 1 to 7 carbon atoms.
一般式（３）としては、Ｒ15がヘキサデシル基、Ｘ9が水素原子、Ｒ16がペンタデシル基、Ｒ17がヒドロキシエチル基のもの；Ｒ15がヘキサデシル基、Ｘ9が水素原子、Ｒ16がノニル基、Ｒ17がヒドロキシエチル基のもの；又はＲ15がヘキサデシル基、Ｘ9がグリセリル基、Ｒ16がトリデシル基、Ｒ17が３−メトキシプロピル基の擬似型セラミド類が好ましく、一般式（３）のＲ15がヘキサデシル基、Ｘ9が水素原子、Ｒ16がペンタデシル基、Ｒ17がヒドロキシエチル基のもの（Ｎ−（ヘキサデシロキシヒドロキシプロピル）−Ｎ−ヒドロキシエチルヘキサデカナミド）が、更に好ましい。 As a general formula (3), R 15 is a hexadecyl group, X 9 is a hydrogen atom, R 16 is a pentadecyl group, and R 17 is a hydroxyethyl group; R 15 is a hexadecyl group, X 9 is a hydrogen atom, and R 16 is a hydrogen atom. Nonyl group, R 17 is a hydroxyethyl group; or R 15 is a hexadecyl group, X 9 is a glyceryl group, R 16 is a tridecyl group, and R 17 is a 3-methoxypropyl group. Pseudo-ceramides are preferable. In 3), R 15 is a hexadecyl group, X 9 is a hydrogen atom, R 16 is a pentadecyl group, and R 17 is a hydroxyethyl group (N- (hexadecyloxyhydroxypropyl) -N-hydroxyethylhexadecanamide). , More preferred.
成分（Ｃ）の化合物は、１種以上を用いることができ、αゲル含有組成物中に０．００１〜１０質量％含有され、好ましくは０．０５〜７質量％、更に０．１〜５質量％含有されるのが、水分保持能、使用感（なじみやすさ）の観点からより好ましい。 One or more compounds of the component (C) can be used, and the α-gel-containing composition contains 0.001 to 10% by mass, preferably 0.05 to 7% by mass, and further 0.1 to 5%. It is more preferably contained in% by mass from the viewpoint of water retention ability and usability (easiness of familiarity).
本発明において、成分（Ａ）、（Ｂ）及び（Ｃ）の質量割合は、（（Ａ）＋（Ｂ））／（（Ａ）＋（Ｂ）＋（Ｃ））＝０．１５以上、更に０．３５〜０．８であるのが、αゲルの保存安定性が高まるので好ましい。
また、成分（Ａ）及び（Ｂ）の質量割合は、（Ａ）／（（Ａ）＋（Ｂ））＝０．１以上、更に０．２５〜０．７５であるのが、しっかりしたαゲル構造を作り、水分保持能を高めることができるので好ましい。
In the present invention, the mass ratio of the components (A), (B) and (C) is ((A) + (B)) / ((A) + (B) + (C)) = 0.15 or more. Further, it is preferably 0.35 to 0.8 because the storage stability of the α-gel is enhanced.
Further, the mass ratio of the components (A) and (B) is (A) / ((A) + (B)) = 0.1 or more, and 0.25 to 0.75 is a firm α. It is preferable because it can form a gel structure and enhance the water retention capacity.
本発明で用いるαゲル含有組成物は、更に次の成分（Ｄ）及び（Ｅ）を含有するのが、αゲル構造の安定化、水分保持能を高くすることができるので好ましい。
（Ｄ）ポリオキシエチレン基を有するＨＬＢ１０以上の非イオン界面活性剤、イオン性界面活性剤及びスフィンゴシン塩類から選ばれる１種以上の化合物、
（Ｅ）水
It is preferable that the α-gel-containing composition used in the present invention further contains the following components (D) and (E) because it can stabilize the α-gel structure and enhance the water retention ability.
(D) One or more compounds selected from HLB 10 or higher nonionic surfactants having a polyoxyethylene group, ionic surfactants and sphingosine salts,
(E) Water
［成分（Ｄ）］
本発明で用いる成分（Ｄ）は、ポリオキシエチレン基を有するＨＬＢ１０以上の非イオン界面活性剤、イオン性界面活性剤及びスフィンゴシン塩類から選ばれる１種以上の化合物である。
成分（Ｄ）の化合物のうち、非イオン界面活性剤は、ポリオキシエチレン基を有するもので、ＨＬＢ１０以上、好ましくはＨＬＢ１２．５〜１５．５の親水性のものである。例えば、ポリオキシエチレン硬化ヒマシ油、ポリオキシエチレンソルビタン脂肪酸エステル、アルキルポリオキシエチレングリセリル、ポリオキシエチレンアルキルエーテル等が挙げられる。
これらのうち、ポリオキシエチレン硬化ヒマシ油、モノステアリン酸ポリオキシエチレンソルビタンが好ましい。
[Component (D)]
The component (D) used in the present invention is one or more compounds selected from nonionic surfactants having a polyoxyethylene group of HLB 10 or more, ionic surfactants and sphingosine salts.
Among the compounds of the component (D), the nonionic surfactant has a polyoxyethylene group and is hydrophilic with an HLB of 10 or more, preferably HLB of 12.5 to 15.5. For example, polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbitan fatty acid ester, alkylpolyoxyethylene glyceryl, polyoxyethylene alkyl ether and the like can be mentioned.
Of these, polyoxyethylene hydrogenated castor oil and polyoxyethylene sorbitan monostearate are preferable.
また、成分（Ｄ）の化合物のうち、イオン性界面活性剤としては、アニオン界面活性剤、カチオン界面活性剤、両性界面活性剤が挙げられる。
アニオン界面活性剤としては、例えば、ラウリン酸ナトリウム、パルミチン酸カリウム、ステアリン酸アルギニン等の炭素数１２〜２４の脂肪酸塩；ラウリル硫酸ナトリウム、ラウリル硫酸カリウム等のアルキル硫酸エステル塩；ポリオキシエチレンラウリル硫酸トリエタノールアミン等のアルキルエーテル硫酸エステル塩；ラウロイルサルコシンナトリウム等のＮ−アシルサルコシン塩；Ｎ−ステアロイル−Ｎ−メチルタウリンナトリウム、Ｎ−ミリストイル−Ｎ−メチルタウリンナトリウム等の脂肪酸アミドスルホン酸塩；モノステアリルリン酸ナトリウム等のアルキルリン酸塩；ポリオキシエチレンオレイルエーテルリン酸ナトリウム、ポリオキシエチレンステアリルエーテルリン酸ナトリウム等のポリオキシエチレンアルキルエーテルリン酸塩；ジ−２−エチルヘキシルスルホコハク酸ナトリウム等の長鎖スルホコハク酸塩；Ｎ−ラウロイルグルタミン酸モノナトリウム、Ｎ−ステアロイル−Ｌ−グルタミン酸ナトリウム、Ｎ−ステアロイル−Ｌ−グルタミン酸アルギニン、Ｎ−ステアロイルグルタミン酸ナトリウム、Ｎ−ミリストイル−Ｌ−グルタミン酸ナトリウム等の長鎖Ｎ−アシルグルタミン酸塩などが挙げられる。
これらのうち、炭素数１２〜２４の脂肪酸塩、脂肪酸アミドスルホン酸塩、ポリオキシエチレンアルキルエーテルリン酸塩、長鎖Ｎ−アシルグルタミン酸塩が好ましく、更に、Ｎ−ステアロイル−Ｎ−メチルタウリンナトリウム、Ｎ−ステアロイル−Ｌ−グルタミン酸アルギニン、ポリオキシチレンステアリルエーテルリン酸ナトリウムが好ましい。
Further, among the compounds of the component (D), examples of the ionic surfactant include an anionic surfactant, a cationic surfactant, and an amphoteric surfactant.
Examples of the anionic surfactant include fatty acid salts having 12 to 24 carbon atoms such as sodium laurate, potassium palmitate, and arginine stearate; alkyl sulfates such as sodium lauryl sulfate and potassium lauryl sulfate; and polyoxyethylene lauryl sulfate. Alkyl ether sulfate ester salts such as triethanolamine; N-acyl sarcosine salts such as sodium lauroyl sarcosin; fatty acid amide sulfonates such as sodium N-stearoyl-N-methyl taurine, sodium N-myristoyl-N-methyl taurine; mono Alkyl phosphates such as sodium stearyl phosphate; polyoxyethylene alkyl ether phosphates such as sodium polyoxyethylene oleyl ether phosphate, sodium polyoxyethylene stearyl ether phosphate; lengths such as sodium di-2-ethylhexyl sulfosuccinate Chain sulfosuccinate; long-chain N- such as monosodium N-lauroyl glutamate, sodium N-stearoyl-L-glutamate, arginine N-stearoyl-L-glutamate, sodium N-stearoyl glutamate, sodium N-myristoyl-L-glutamate, etc. Examples include acyl glutamate.
Of these, fatty acid salts having 12 to 24 carbon atoms, fatty acid amide sulfonates, polyoxyethylene alkyl ether phosphates, and long-chain N-acylglutamic acid salts are preferable, and N-stearoyl-N-methyltaurine sodium, Arginine N-stearoyl-L-glutamic acid and sodium polyoxythylene stearyl ether phosphate are preferred.
また、カチオン界面活性剤としては、第４級アンモニウム塩が好ましく、例えば、塩化ステアリウムトリメチルアンモニウム、塩化ラウリルトリメチルアンモニウム等のアルキルトリメチルアンモニウム塩；ジアルキルジメチルアンモニウム、トリアルキルメチルアンモニウム塩、アルキルアミン塩などが挙げられる。 The quaternary ammonium salt is preferable as the cationic surfactant, and for example, alkyltrimethylammonium salts such as stearium trimethylammonium chloride and lauryltrimethylammonium chloride; dialkyldimethylammonium, trialkylmethylammonium salt, alkylamine salts and the like. Can be mentioned.
更に、両性界面活性剤としては、アルキルジメチルアミンオキシド、アルキルカルボキシベタイン、アルキルスルホベタイン、アミドアミノ酸塩、アルキルアミドプロピルベタインが挙げられ、更にアルキルアミドプロピルベタインが好ましい。 Further, examples of the amphoteric surfactant include alkyldimethylamine oxide, alkylcarboxybetaine, alkylsulfobetaine, amide amino acid salt and alkylamidepropyl betaine, and alkylamide propyl betaine is more preferable.
本発明で用いる成分（Ｄ）の化合物のうち、スフィンゴシン塩類とは、スフィンゴシン類と酸性物質とから構成されるものである。スフィンゴシン類としては、一般式（４）で表わされるものが挙げられる。 Among the compounds of the component (D) used in the present invention, sphingosine salts are composed of sphingosines and acidic substances. Examples of sphingosines include those represented by the general formula (4).
（式中、Ｒ21はヒドロキシル基、カルボニル基又はアミノ基が置換していてもよい、炭素数４〜３０の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基を示し；Ｙはメチレン基、メチン基又は酸素原子を示し；Ｘ11、Ｘ12、及びＸ13は各々独立して水素原子、ヒドロキシル基又はアセトキシ基を示し、Ｘ14は水素原子、アセチル基又はグリセリル基を示すか、隣接する酸素原子と一緒になってオキソ基を形成し（但し、Ｙがメチン基のとき、Ｘ11とＸ12のいずれか一方が水素原子であり、他方は存在しない。Ｘ14がオキソ基を形成するとき、Ｘ13は存在しない。）；Ｒ22及びＲ23は各々独立して水素原子、ヒドロキシル基、ヒドロキシメチル基又はアセトキシメチル基を示し；ａ個のＲ1は各々独立して水素原子又はアミジノ基であるか、ヒドロキシル基、ヒドロキシアルコキシ基、アルコキシ基及びアセトキシ基から選ばれる置換基を有していてもよい総炭素数１〜８の直鎖又は分岐鎖の飽和又は不飽和の炭化水素基を示し；ａは２又は３の数を示し；破線部は不飽和結合であってもよいことを示す） (In the formula, R 21 represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 4 to 30 carbon atoms, which may be substituted with a hydroxyl group, a carbonyl group or an amino group; Y is Does it represent a methylene group, a methine group or an oxygen atom; X 11 , X 12 and X 13 independently represent a hydrogen atom, a hydroxyl group or an acetoxy group, and X 14 represents a hydrogen atom, an acetyl group or a glyceryl group? , Forming an oxo group together with adjacent oxygen atoms (however, when Y is a methine group, one of X 11 and X 12 is a hydrogen atom and the other does not exist. X 14 is an oxo group. X 13 is absent.); R 22 and R 23 each independently represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an acetoxymethyl group; a R 1 are each independently hydrogen. Saturated or unsaturated linear or branched chain with 1-8 total carbon atoms, which may be an atomic or amidino group or may have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group. Indicates a hydrocarbon group; a indicates a number of 2 or 3; a broken line indicates an unsaturated bond)
式中、Ｒ21は、ヒドロキシル基、カルボニル基又はアミノ基が置換していてもよい、炭素数４〜３０、好ましくはヒドロキシル基が置換していてもよい炭素数７〜２２の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基である。炭素数１０〜２０の直鎖又は分岐鎖のアルキル基、Ｙ側末端にヒドロキシル基を持つ炭素数１０〜２０の直鎖又は分岐鎖のアルキル基で、分岐鎖アルキル基の場合は分岐鎖がメチル分岐のもの等が好ましい。具体的には、トリデシル基、テトラデシル基、ペンタデシル基、ヘキサデシル基、１−ヒドロキシトリデシル基、１−ヒドロキシペンタデシル基、イソヘキサデシル基、イソステアリル基が好ましい。 In the formula, R 21 is a straight chain or branched having 4 to 30 carbon atoms, preferably 7 to 22 carbon atoms which may be substituted with a hydroxyl group, a carbonyl group or an amino group. It is a chain or cyclic saturated or unsaturated hydrocarbon group. A linear or branched alkyl group having 10 to 20 carbon atoms, a linear or branched alkyl group having 10 to 20 carbon atoms having a hydroxyl group at the Y-side terminal, and in the case of a branched chain alkyl group, the branched chain is methyl. Branched ones and the like are preferable. Specifically, a tridecylic group, a tetradecyl group, a pentadecyl group, a hexadecyl group, a 1-hydroxytridecyl group, a 1-hydroxypentadecyl group, an isohexadecyl group, and an isostearyl group are preferable.
Ｙはメチレン基（ＣＨ2）、メチン基（ＣＨ）又は酸素原子のいずれかを示す。
Ｘ11、Ｘ12、及びＸ13は、各々独立して水素原子、ヒドロキシル基又はアセトキシ基を示し、Ｘ14は水素原子、アセチル基、グリセリル基、隣接する酸素原子と一緒になってオキソ基を形成する置換基を示す。Ｘ11、Ｘ12、及びＸ13のうち０〜１個がヒドロキシル基で、残余が水素原子、及びＸ14が水素原子であるものが好ましい。なお、Ｙがメチン基のとき、Ｘ11とＸ12のいずれか一方のみが水素原子であり、他方は存在しない。また、Ｘ14がオキソ基を形成するとき、Ｘ13は存在しない。
Y represents either a methylene group (CH 2 ), a methine group (CH) or an oxygen atom.
X 11 , X 12 , and X 13 each independently represent a hydrogen atom, a hydroxyl group, or an acetoxy group, and X 14 forms an oxo group together with a hydrogen atom, an acetyl group, a glyceryl group, and an adjacent oxygen atom. Indicates the substituent to be formed. It is preferable that 0 to 1 of X 11 , X 12 , and X 13 are hydroxyl groups, the remainder is a hydrogen atom, and X 14 is a hydrogen atom. When Y is a methine group, only one of X 11 and X 12 is a hydrogen atom, and the other does not exist. Also, when X 14 forms an oxo group, X 13 does not exist.
Ｒ22及びＲ23は各々独立して水素原子、ヒドロキシル基、ヒドロキシメチル基又はアセトキシメチル基を示し、更にＲ23は水素原子であることが好ましい。 It is preferable that R 22 and R 23 independently represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an acetoxymethyl group, and R 23 is a hydrogen atom.
また、ａは２又は３の数を示し、ａが２のときＲ1はＲ24及びＲ25を示し、ａが３のときＲ1はＲ24、Ｒ25及びＲ26を示す。 Further, a indicates a number of 2 or 3, when a is 2, R 1 indicates R 24 and R 25 , and when a is 3, R 1 indicates R 24 , R 25 and R 26 .
Ｒ24、Ｒ25及びＲ26は、各々独立して水素原子又はアミジノ基であるか、ヒドロキシル基、ヒドロキシアルコキシ基、アルコキシ基及びアセトキシ基から選ばれる置換基を有していてもよい総炭素数１〜８の直鎖又は分岐鎖の飽和又は不飽和の炭化水素基を示す。ここで炭化水素基に置換し得るヒドロキシアルコキシ基としては炭素数１〜７の直鎖又は分岐鎖のヒドロキシアルコキシ基が好ましい。またアルコキシ基としては炭素数１〜７の直鎖又は分岐鎖のアルコキシ基が好ましい。Ｒ24、Ｒ25及びＲ26としては、例えば水素原子；メチル、エチル、プロピル、２−エチルへキシル、イソプロピル等の直鎖又は分岐鎖アルキル基；ビニル、アリル等のアルケニル基；アミジノ基；ヒドロキシメチル、２−ヒドロキシエチル、１，１−ジメチル−２−ヒドロキシエチル、２−ヒドロキシプロピル、２，３−ジヒドロキシプロピル、２−ヒドロキシ−３−メトキシプロピル、２，３，４，５，６−ペンタヒドロキシへキシル、１，１−ビス（ヒドロキシメチル）エチル、２−（２−ヒドロキシエトキシ）エチル、２−メトキシエチル、１−メチル−２−ヒドロキシエチル、３−ヒドロキシプロピル、３−メトキシプロピル、１，１−ビス（ヒドロキシメチル）−２−ヒドロキシエチル等のヒドロキシル基、ヒドロキシアルコキシ基及びアルコキシ基から選ばれる１〜６個が置換した総炭素数１〜８の炭化水素基が挙げられる。 R 24 , R 25 and R 26 may each independently be a hydrogen atom or an amidino group or have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group. Shows 1 to 8 linear or branched saturated or unsaturated hydrocarbon groups. Here, as the hydroxyalkoxy group that can be substituted with the hydrocarbon group, a linear or branched hydroxyalkoxy group having 1 to 7 carbon atoms is preferable. Further, as the alkoxy group, a linear or branched alkoxy group having 1 to 7 carbon atoms is preferable. Examples of R 24 , R 25 and R 26 include hydrogen atoms; linear or branched alkyl groups such as methyl, ethyl, propyl, 2-ethylhexyl and isopropyl; alkenyl groups such as vinyl and allyl; amidino groups; hydroxy. Methyl, 2-hydroxyethyl, 1,1-dimethyl-2-hydroxyethyl, 2-hydroxypropyl, 2,3-dihydroxypropyl, 2-hydroxy-3-methoxypropyl, 2,3,4,5,6-penta Hydroxyhexyl, 1,1-bis (hydroxymethyl) ethyl, 2- (2-hydroxyethoxy) ethyl, 2-methoxyethyl, 1-methyl-2-hydroxyethyl, 3-hydroxypropyl, 3-methoxypropyl, 1 , 1-Hydroxymethyl -2-Hydroxyethyl and other hydroxyl groups, hydroxyalkoxy groups and hydrocarbon groups with a total carbon number of 1 to 8 substituted with 1 to 6 selected from the alkoxy groups.
これらのうち、水素原子、又はメチル基、２−ヒドロキシエチル、１，１−ジメチル−２−ヒドロキシエチル、１，１−ビス（ヒドロキシメチル）エチル、２−（２−ヒドロキシエトキシ）エチル等のヒドロキシル基及びヒドロキシアルコキシ基から選ばれる１〜３個が置換していてもよいアルキル基が好ましい。 Of these, a hydrogen atom or a methyl group, a hydroxyl group such as 2-hydroxyethyl, 1,1-dimethyl-2-hydroxyethyl, 1,1-bis (hydroxymethyl) ethyl, 2- (2-hydroxyethoxy) ethyl, etc. Alkyl groups selected from groups and hydroxyalkoxy groups, in which 1 to 3 may be substituted, are preferable.
一般式（４）で表わされるスフィンゴシン類としては、次の一般式（５）で表わされる天然由来のスフィンゴシン類又は同構造の合成物、及びその誘導体（以下、天然型スフィンゴシンと記載する。）又は一般式（６）で表わされるスフィンゴシン構造を有する擬似型スフィンゴシン類（以下、擬似型スフィンゴシンと記載する。）が好ましい。
（Ｉ）一般式（５）で表わされる天然型スフィンゴシン。
Examples of sphingosine represented by the general formula (4) include naturally occurring sphingosine represented by the following general formula (5) or a compound having the same structure, and a derivative thereof (hereinafter, referred to as natural sphingosine) or. Pseudo-sphingosine having a sphingosine structure represented by the general formula (6) (hereinafter, referred to as pseudo-sphingosine) is preferable.
(I) Natural sphingosine represented by the general formula (5).
（式中、Ｒ27はヒドロキシル基が置換していてもよい炭素数７〜１９の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基を示し；Ｙ1はメチレン基又はメチン基を示し；Ｘ15、Ｘ16及びＸ17は各々独立して水素原子、ヒドロキシル基又はアセトキシ基を示し、Ｘ18は水素原子を示すか、隣接する酸素原子と一緒になってオキソ基を形成し（但し、Ｙ1がメチン基のとき、Ｘ15とＸ16のいずれか一方が水素原子を示し、他方は存在しない。Ｘ18がオキソ基を形成するとき、Ｘ17は存在しない。）；Ｒ28はヒドロキシメチル基又はアセトキシメチル基を示し；ａ個のＲ2は各々独立して水素原子又はアミジノ基であるか、ヒドロキシル基、ヒドロキシアルコキシ基、アルコキシ基及びアセトキシ基から選ばれる置換基を有していてもよい総炭素数１〜４の直鎖又は分岐鎖の飽和又は不飽和炭化水素基を示し；ａは２又は３の数を示し；破線部は不飽和結合があってもよいことを示す） (In the formula, R 27 represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 7 to 19 carbon atoms in which the hydroxyl group may be substituted; Y 1 represents a methylene group or a methine group. Show; X 15 , X 16 and X 17 each independently represent a hydrogen atom, a hydroxyl group or an acetoxy group, and X 18 represents a hydrogen atom or together with an adjacent oxygen atom to form an oxo group ( However, when Y 1 is a methine group, one of X 15 and X 16 indicates a hydrogen atom and the other does not exist. When X 18 forms an oxo group, X 17 does not exist.); R 28 represents a hydroxymethyl group or an acetoxymethyl group; a number of R 2 is each independently a hydrogen atom or an amidino group, a hydroxyl group, hydroxyalkoxy group, substituent selected from alkoxy and acetoxy groups Indicates a saturated or unsaturated hydrocarbon group of a linear or branched chain having a total carbon number of 1 to 4; a indicates a number of 2 or 3; a broken line portion may have an unsaturated bond. Show)
ここでＲ27としては、炭素数７〜１９の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基が好ましく、更に炭素数１３〜１５の直鎖の飽和又は不飽和の炭化水素基が好ましい。ａは２が好ましく、Ｒ2は各々独立して水素原子、又は炭素数１〜４の直鎖もしくは分岐のアルキル基が好ましい。 Here, as R 27 , a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 7 to 19 carbon atoms is preferable, and a linear saturated or unsaturated hydrocarbon group having 13 to 15 carbon atoms is preferable. Is preferable. 2 is preferable for a, and R 2 is preferably a hydrogen atom independently or a linear or branched alkyl group having 1 to 4 carbon atoms.
一般式（５）で表わされる天然型スフィンゴシンとしては、具体的には、天然のスフィンゴシン、ジヒドロスフィンゴシン、フィトスフィンゴシン、スフィンガジエニン、デヒドロスフィンゴシン、デヒドロフィトスフィンゴシン、及びこれらのＮ−アルキル体（例えばＮ−メチル体）等が挙げられる。
これらのスフィンゴシンは天然型（Ｄ（＋）体）の光学活性体を用いても、非天然型（Ｌ（−）体）の光学活性体を用いても、更に天然型と非天然型の混合物を用いてもよい。
上記化合物の相対立体配置は、天然型の立体配置のものでも、それ以外の非天然型の立体配置のものでも良く、また、これらの混合物によるものでもよい。
更に、PHYTOSPHINGOSINE(INCI名；8th Edition)及び次式で表わされるものが好ましい。
Specific examples of the natural sphingosine represented by the general formula (5) include natural sphingosine, dihydrosphingosine, phytosphingosine, sphingosine, dehydrosphingosine, dehydrosphingosine, and N-alkyl compounds thereof (for example,). N-methyl form) and the like.
These sphingosines are a mixture of natural and non-natural types, whether they use natural (D (+)) optically active substances or non-natural (L (-)) optically active substances. May be used.
The relative configuration of the compound may be a natural configuration, a non-natural configuration other than that, or a mixture thereof.
Further, PHYTOSPHINGOSINE (INCI name; 8th Edition) and those represented by the following equations are preferable.
これらは、天然からの抽出物及び合成物のいずれでもよく、市販のものを用いることができる。
天然型スフィンゴシンの市販のものとしては、例えば、D-Sphingosine(4-Sphingenine)(SIGMA-ALDRICH社)、DS-phytosphingosine (DOOSAN社)、phytosphingosine（コスモファーム社）が挙げられる。
These may be either natural extracts or synthetics, and commercially available ones can be used.
Examples of commercially available natural sphingosine include D-Sphingosine (4-Sphingenine) (SIGMA-ALDRICH), DS-phytosphingosine (DOOSAN), and phytosphingosine (Cosmofarm).
（II）一般式（６）で表わされる擬似型スフィンゴシン。 (II) Pseudo-type sphingosine represented by the general formula (6).
（式中、Ｒ29はヒドロキシル基が置換していてもよい炭素数１０〜２２の直鎖、分岐鎖又は環状の飽和又は不飽和の炭化水素基を示し；Ｘ19は水素原子、アセチル基又はグリセリル基を示し；ａ個のＲ3は各々独立して水素原子又はアミジノ基を示すか、ヒドロキシル基、ヒドロキシアルコキシ基、アルコキシ基及びアセトキシ基から選ばれる置換基を有していてもよい総炭素数１〜８の直鎖又は分岐鎖の飽和又は不飽和の炭化水素基を示し、ａは２又は３の数を示す） (In the formula, R 29 represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 10 to 22 carbon atoms in which the hydroxyl group may be substituted; X 19 is a hydrogen atom, acetyl group or Shows a glyceryl group; a R 3 each independently represents a hydrogen atom or an amidino group, or may have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group. Indicates a saturated or unsaturated hydrocarbon group of the number 1 to 8 of the linear or branched chain, and a indicates the number of 2 or 3).
ここでＲ29としては、炭素数１４〜２０のイソ分岐アルキル基が好ましく、更にイソステアリル基が好ましい。イソステアリル基は、動植物油由来の脂肪酸を用いたダイマー酸製造時の副生成物由来のイソステアルアルコールを原料油として得られるイソステアリル基がもっとも好ましい。
また、ａが２のときＲ3はＲ30及びＲ31を示し、ａが３のときＲ3はＲ30、Ｒ31及びＲ32である。
Here, as R 29 , an isobranched alkyl group having 14 to 20 carbon atoms is preferable, and an isostearyl group is more preferable. The isostearyl group is most preferably an isostearyl group obtained by using an isostearyl alcohol derived from a by-product during the production of dimer acid using a fatty acid derived from an animal or vegetable oil as a raw material oil.
When a is 2, R 3 indicates R 30 and R 31 , and when a is 3, R 3 is R 30 , R 31 and R 32 .
Ｒ30、Ｒ31及びＲ32は、例えば水素原子；メチル、エチル、プロピル、２−エチルへキシル、イソプロピル等の直鎖又は分岐鎖のアルキル基；ビニル、アリル等のアルケニル基；アミジノ基；ヒドロキシメチル、２−ヒドロキシエチル、１，１−ジメチル−２−ヒドロキシエチル、２−ヒドロキシプロピル、２，３−ジヒドロキシプロピル、２−ヒドロキシ−３−メトキシプロピル、２，３，４，５，６−ペンタヒドロキシへキシル、１，１−ビス（ヒドロキシメチル）エチル、２−（２−ヒドロキシエトキシ）エチル、２−メトキシエチル、１−メチル−２−ヒドロキシエチル、３−ヒドロキシプロピル、３−メトキシプロピル、１，１−ビス（ヒドロキシメチル）−２−ヒドロキシエチル等のヒドロキシル基、ヒドロキシアルコキシ基及びアルコキシ基から選ばれる置換基を有する総炭素数１〜８のアルキル基が挙げられる。
これらのうち、Ｒ30及びＲ31のいずれか１つが水素原子で、他方が２−ヒドロキシエチル、１，１−ジメチル−２−ヒドロキシエチル、１，１−ビス（ヒドロキシメチル）エチル、２−（２−ヒドロキシエトキシ）エチルである２級アミンが好ましい。
R 30 , R 31 and R 32 are, for example, hydrogen atoms; linear or branched alkyl groups such as methyl, ethyl, propyl, 2-ethylhexyl and isopropyl; alkenyl groups such as vinyl and allyl; amidino groups; hydroxy. Methyl, 2-hydroxyethyl, 1,1-dimethyl-2-hydroxyethyl, 2-hydroxypropyl, 2,3-dihydroxypropyl, 2-hydroxy-3-methoxypropyl, 2,3,4,5,6-penta Hydroxyhexyl, 1,1-bis (hydroxymethyl) ethyl, 2- (2-hydroxyethoxy) ethyl, 2-methoxyethyl, 1-methyl-2-hydroxyethyl, 3-hydroxypropyl, 3-methoxypropyl, 1 , 1-Bis (Hydroxymethyl) -2-Hydroxyethyl and other hydroxyl groups, hydroxyalkoxy groups and alkyl groups having a total carbon number of 1 to 8 having a substituent selected from the alkoxy groups.
Of these, any one of R 30 and R 31 is a hydrogen atom, and the other is 2-hydroxyethyl, 1,1-dimethyl-2-hydroxyethyl, 1,1-bis (hydroxymethyl) ethyl, 2- ( A secondary amine that is 2-hydroxyethoxy) ethyl is preferred.
擬似型スフィンゴシンとしては、Ｒ29がイソステアリル基、Ｘ19が水素原子で、Ｒ30が水素原子、Ｒ31が２−ヒドロキシエチル基、１，１−ビス（ヒドロキシメチル）エチル基、１，１−ジメチル−２−ヒドロキシエチル基、又は２−（２−ヒドロキシエトキシ）エチル基等のヒドロキシル基及びヒドロキシアルコキシ基から選ばれる１〜３個が置換したアルキル基であるものが好ましい。
擬似型スフィンゴシンの具体例としては、次の擬似型スフィンゴシン（ｉ）〜（iv）が挙げられる。
As the pseudo-sphingosin, R 29 is an isostearyl group, X 19 is a hydrogen atom, R 30 is a hydrogen atom, R 31 is a 2-hydroxyethyl group, 1,1-bis (hydroxymethyl) ethyl group, 1,1 It is preferable that the alkyl group is substituted with 1 to 3 selected from a hydroxyl group such as a −dimethyl-2-hydroxyethyl group or a 2- (2-hydroxyethoxy) ethyl group and a hydroxyalkoxy group.
Specific examples of the pseudo-sphingosine include the following pseudo-sphingosine (i) to (iv).
スフィンゴシン類としては、スフィンゴシン、フィトスフィンゴシン、擬似型スフィンゴシンが好ましく、更には、擬似型スフィンゴシン（ii）、１−（２−ヒドロキシエチルアミノ）−３−イソステアリルオキシ−２−プロパノールが好ましい。 As the sphingosines, sphingosine, phytosphingosine, and pseudo-sphingosine are preferable, and pseudo-sphingosine (ii) and 1- (2-hydroxyethylamino) -3-isostearyloxy-2-propanol are preferable.
これらのスフィンゴシン、フィトスフィンゴシン、擬似型スフィンゴシンと塩を構成する酸性物質としては、グルタミン酸、アスパラギン酸等の酸性アミノ酸；リン酸、塩酸等の無機酸；酢酸等のモノカルボン酸；コハク酸等のジカルボン酸；クエン酸、乳酸、リンゴ酸等のオキシカルボン酸などが挙げられる。これらの中で、スフィンゴシン、フィトスフィンゴシン、擬似型スフィンゴシン（擬似型スフィンゴシン（ii）、１−（２−ヒドロキシエチルアミノ）−３−イソステアリルオキシ−２−プロパノール）のコハク酸塩、乳酸塩、グルタミン酸塩が好ましく、更に、スフィンゴシン、フィトスフィンゴシン、擬似型スフィンゴシンのグルタミン酸塩が好ましい。 Acidic amino acids such as glutamate and aspartic acid; inorganic acids such as phosphoric acid and hydrochloric acid; monocarboxylic acids such as acetic acid; dicarboxylic acids such as succinic acid, as acidic substances constituting salts with these sphingosine, phytosphingocin, and pseudo-sphingosin. Acids: Examples include oxycarboxylic acids such as citric acid, lactic acid and malic acid. Among these, sphingosine, phytosphingosine, pseudo-sphingosine (pseudo-sphingosine (ii), 1- (2-hydroxyethylamino) -3-isostearyloxy-2-propanol) succinate, lactate, glutamate Salts are preferred, and sphingosine, phytosphingosine, and pseudosphingosine glutamates are preferred.
成分（Ｄ）としては、アニオン界面活性剤、スフィンゴシン塩類を用いるのが、電荷反発の効果によって、ラメラの層間に多量の水分を抱え込めるため、保水性の観点からより好ましい。中でも、Ｎ−ステアロイル−Ｎ−メチルタウリンナトリウム、ポリオキシエチレンステアリルエーテルリン酸ナトリウム、Ｎ−ステアロイル−Ｌ−グルタミン酸アルギニン、フィトスフィンゴシンのグルタミン酸塩、及び擬似型スフィンゴシンのグルタミン酸塩が、少ない量で安定な乳化物が得られる点で好ましく、Ｎ−ステアロイル−Ｌ−グルタミン酸アルギニンが、より好ましい。
成分（Ｄ）は、１種以上を用いることができ、αゲル含有組成物中に好ましくは０．０００１２〜１０質量％含有され、より好ましくは０．０１〜７質量％、更に０．２〜３質量％含有されるのが、成分（Ａ）、（Ｂ）及び（Ｃ）で作るラメラ構造の層間隔を広げ、層間に水分を多く蓄える構造を形成するのに役立つので好ましい。
As the component (D), an anionic surfactant and sphingosine salts are more preferable from the viewpoint of water retention because a large amount of water is held between the layers of the lamella due to the effect of charge repulsion. Among them, sodium N-stearoyl-N-methyltaurine, sodium polyoxyethylene stearyl ether phosphate, arginine N-stearoyl-L-glutamic acid, glutamate of phytosphingosin, and glutamate of pseudo-sphingosin are stable in a small amount. It is preferable in that an emulsion can be obtained, and arginine N-stearoyl-L-glutamic acid is more preferable.
One or more kinds of the component (D) can be used, and the α-gel-containing composition preferably contains 0.00012 to 10% by mass, more preferably 0.01 to 7% by mass, and further 0.2 to 0.2 to The content of 3% by mass is preferable because it helps to widen the layer spacing of the lamellar structure formed by the components (A), (B) and (C) and to form a structure that stores a large amount of water between layers.
本発明において、成分（Ｅ）の水は、αゲル含有組成物中に２０〜９９．９質量％含有されるのが好ましく、４０〜９５質量％、更に５０〜９０質量％含有されるのが好ましい。 In the present invention, the water of the component (E) is preferably contained in the α-gel-containing composition in an amount of 20 to 99.9% by mass, preferably 40 to 95% by mass, and further 50 to 90% by mass. preferable.
また、その他の水性基剤、例えばエタノール、プロパノール等の炭素数１〜４の低級アルコール、エリスリトール、トレイトール、キシリトール、マンニトール等の糖アルコールなどを含有することもできる。 It can also contain other aqueous bases such as lower alcohols having 1 to 4 carbon atoms such as ethanol and propanol, sugar alcohols such as erythritol, threitol, xylitol and mannitol.
本発明においては、前記成分のそれぞれの好ましい成分、及び好ましい含有量を組み合わせるのが、より好ましい。
更に、成分（Ａ）がモノベヘン酸グリセリル及びジステアリン酸ソルビタン、成分（Ｂ）がセタノール、成分（Ｃ）が一般式（１）で表される化合物、成分（Ｄ）がステアロイルグルタミン酸塩、成分（Ｅ）が水であるものが、より好ましい。
In the present invention, it is more preferable to combine each preferable component of the above components and a preferable content.
Further, the component (A) is glyceryl monobehate and sorbitan distearate, the component (B) is cetanol, the component (C) is a compound represented by the general formula (1), the component (D) is stearoyl glutamate, and the component (E). ) Is water, which is more preferable.
本発明の乳化組成物は、更に、油性成分を含有することができる。例えば、流動パラフィン、スクワラン、ワセリン等の炭化水素油；セチルジメチルブチルエーテル、エチレングリコールジオクチルエーテル、グリセロールモノオレイルエーテル等のエーテル油；ミリスチン酸オクチルドデシル、パルミチン酸イソプロピル、ステアリン酸ブチル、アジピン酸ジ−２−エチルヘキシル、ジカプリン酸ネオペンチルグリコール、トリオクタノイン等のエステル油；ステアリン酸、ベヘン酸、イソミリスチン酸等の高級脂肪酸；オリーブ油等の植物油；ジメチルポリシロキサン、環状ジメチルポリシロキサン、メチルフェニルポリシロキサン、アミノ変性シリコーン、カルボキシ変性シリコーン、アルコール変性シリコーン、アルキル変性シリコーン、ポリエーテル変性シリコーン、フッ素変性シリコーン等のシリコーン油；パーフルオロアルキルエチルリン酸、パーフルオロアルキルポリオキシエチレンリン酸、パーフルオロポリエーテル、ポリテトラフルオロエチレン等のフッ素系油などが挙げられる。これらの油性成分は、αゲル含有組成物中に０〜２０質量％含有されるのが好ましい。 The emulsified composition of the present invention can further contain an oily component. For example, hydrocarbon oils such as liquid paraffin, squalane, vaseline; ether oils such as cetyldimethylbutyl ether, ethylene glycol dioctyl ether, glycerol monooleyl ether; octyldodecyl myristate, isopropyl palmitate, butyl stearate, di-2 adipate. -Ester oils such as ethylhexyl, neopentyl glycol dicaprate, trioctanoin; higher fatty acids such as stearic acid, behenic acid, isomilystinic acid; vegetable oils such as olive oil; dimethylpolysiloxane, cyclic dimethylpolysiloxane, methylphenylpolysiloxane, Silicone oils such as amino-modified silicones, carboxy-modified silicones, alcohol-modified silicones, alkyl-modified silicones, polyether-modified silicones, and fluorine-modified silicones; perfluoroalkylethyl phosphate, perfluoroalkylpolyoxyethylene phosphoric acid, perfluoropolyether, Examples include fluorine-based oils such as polytetrafluoroethylene. These oily components are preferably contained in the α-gel-containing composition in an amount of 0 to 20% by mass.
また、本発明のαゲル含有組成物は、通常の化粧料に用いられる有効成分や添加剤、例えば、アスコルビン酸、ニコチン酸アミド、ニコチン酸等の水溶性ビタミン類；オウバクエキス、カンゾウエキス、アロエエキス、スギナエキス、茶エキス、キューカンバーエキス、チョウジエキス、ニンジンエキス、ハマメリス抽出液、プラセンタエキス、海藻エキス、マロニエエキス、ユズエキス、アスナロエキス、ローヤルゼリーエキス、ユーカリエキス、アスナロ抽出液等の動・植物抽出液；水酸化カリウム、水酸化ナトリウム、トリエタノールアミン、炭酸ナトリウム等の塩基；クエン酸、酒石酸、乳酸、リン酸、コハク酸、アジピン酸等の酸；カルボキシビニルポリマー、アルギン酸ナトリウム、カラギーナン、カルボキシメチルセルロース、ヒドロキシエチルセルロース、グアーガム、キサンタンガム、カルボキシメチルキトサン、ヒアルロン酸ナトリウム、オキサゾリン変性シリコーン、Ｎ，Ｎ−ジメチルアミノエチルメタクリル酸ジエチル硫酸塩・Ｎ，Ｎ−ジメチルアクリルアミド・ジメタクリル酸ポリエチレングリコール共重合体等の増粘剤などを含有することもできる。 In addition, the α-gel-containing composition of the present invention contains active ingredients and additives used in ordinary cosmetics, such as water-soluble vitamins such as ascorbic acid, nicotinic acid amide, and nicotinic acid; Oubaku extract, carrageenan extract, and aloe. Animal and plant extracts such as extracts, sugina extract, tea extract, cucumber extract, chowji extract, carrot extract, hamamelis extract, placenta extract, seaweed extract, marronnier extract, yuzu extract, asnarro extract, royal jelly extract, eucalyptus extract, asnarro extract, etc. Liquid; bases such as potassium hydroxide, sodium hydroxide, triethanolamine, sodium carbonate; acids such as citric acid, tartaric acid, lactic acid, phosphoric acid, succinic acid, adipic acid; carboxyvinyl polymer, sodium alginate, carrageenan, carboxymethyl cellulose , Hydroxyethyl cellulose, guar gum, xanthan gum, carboxymethyl chitosan, sodium hyaluronate, oxazoline-modified silicone, N, N-dimethylaminoethyl methacrylate diethyl sulfate, N, N-dimethylacrylamide, polyethylene glycol dimethacrylate, etc. It can also contain a thickener or the like.
本発明のαゲル含有組成物のうち、成分（Ａ）〜（Ｅ）を含有するαゲル含有組成物は、成分（Ａ）〜（Ｄ）（油性成分を含む場合は、成分（Ａ）〜（Ｄ）及び油性成分）を含む混合成分と、成分（Ｅ）を含む水相成分を混合して乳化させる方法により製造することができる。 Among the α-gel-containing compositions of the present invention, the α-gel-containing compositions containing the components (A) to (E) are the components (A) to (D) (when the oily component is contained, the components (A) to (A) to). It can be produced by a method of mixing and emulsifying a mixed component containing (D) and an oily component) and an aqueous phase component containing the component (E).
得られる組成物は、αゲル（α型結晶）であり、結晶（γ型結晶）の析出が抑制される。αゲルは、Ｘ線による構造解析により、確認することができる。α型構造は六方晶系のことであり、親油基が親水基層の面に対して直角に配向しており、Bragg角21〜23°付近に鋭い一本の回折ピークが現れるのが特徴である。
また、本発明のαゲル含有組成物は、水中油型乳化組成物であり、例えば、化粧水、乳液、クリーム、ジェル等の化粧料や、皮膚外用剤として好適である。
The obtained composition is an α gel (α type crystal), and precipitation of crystals (γ type crystal) is suppressed. The α-gel can be confirmed by structural analysis using X-rays. The α-type structure is a hexagonal system, in which the parent oil group is oriented at right angles to the surface of the hydrophilic base layer, and a sharp diffraction peak appears near the Bragg angle of 21 to 23 °. is there.
The α-gel-containing composition of the present invention is an oil-in-water emulsified composition, and is suitable as a cosmetic such as a lotion, a milky lotion, a cream, or a gel, or as an external preparation for the skin.
本発明のシート状化粧料は、シート基材にαゲル含有組成物を含浸させることにより得ることができる。
αゲル含有組成物をシート基材に含浸させる方法に制限はなく、目的に応じて適宜選択することができ、例えば、シート基材に含浸させるαゲル含有組成物を滴下又は噴霧する方法や、シート基材をαゲル含有組成物中に浸漬する方法等が挙げられる。含浸後は、含浸させたαゲル含有組成物中の成分の揮発を防止するため、密封性の高いアルミパウチ等でシート状化粧料を包装して提供することが好ましい。
シート状化粧料中のαゲル含有組成物の含浸率は、貼付時の密着感や使用感（しっとり感）、またシート基材からの液だれを抑える観点から、シート基材１００質量部に対し、好ましくは１００〜２０００質量部であり、より好ましくは５００〜１５００質量部であり、更に好ましくは７００〜１２００質量部である。
The sheet-shaped cosmetic of the present invention can be obtained by impregnating a sheet base material with an α-gel-containing composition.
The method of impregnating the sheet base material with the α-gel-containing composition is not limited and may be appropriately selected depending on the intended purpose. For example, a method of dropping or spraying the α-gel-containing composition to be impregnated with the sheet base material, or Examples thereof include a method of immersing the sheet base material in the α-gel-containing composition. After impregnation, in order to prevent volatilization of the components in the impregnated α-gel-containing composition, it is preferable to wrap the sheet-shaped cosmetics in an aluminum pouch or the like having a high sealing property.
The impregnation rate of the α-gel-containing composition in the sheet-shaped cosmetics is based on 100 parts by mass of the sheet base material from the viewpoints of adhesion and usability (moist feeling) at the time of application and suppression of dripping from the sheet base material. , It is preferably 100 to 2000 parts by mass, more preferably 500 to 1500 parts by mass, and further preferably 700 to 1200 parts by mass.
本発明のシート状化粧料は、多量のαゲルを肌上にべたつくことなく残留させ、かつその後にファンデーションを塗布した場合でも、粉体を均一に付着させることができるものであるが、肌へのなじみやすさやしっとり感、粉体の均一付着性の観点から、シート基材単位面積当たりのαゲル量を、０．２〜４．０ｍｇ/ｃｍ2とするのが好ましく、１．０〜３．０ｍｇ/ｃｍ2とするのがより好ましい。この際、αゲル量は、αゲル含有組成物中の、成分（Ａ）〜（Ｄ）の総質量として求めることができる。 The sheet-shaped cosmetic of the present invention allows a large amount of α-gel to remain on the skin without stickiness, and even when a foundation is applied thereafter, the powder can be uniformly adhered to the skin. From the viewpoint of familiarity, moist feeling, and uniform adhesion of powder, the amount of α-gel per unit area of the sheet base material is preferably 0.2 to 4.0 mg / cm 2 , preferably 1.0 to 3. More preferably, it is 0.0 mg / cm 2 . At this time, the amount of α-gel can be determined as the total mass of the components (A) to (D) in the α-gel-containing composition.
本発明のシート状化粧料を構成するシート基材は、限定されず、本発明のαゲル含有組成物を含浸可能なシート状の支持体である。本発明のシート基材としては、織布または不織布が好ましい。本発明のシート基材は、積層体（すなわち、積層シート）であってもよく、たとえば、織布の積層体、不織布の積層体、織布と不織布の積層体などであってもよい。本発明のシート基材は、使用感の向上、加工のし易さ等の観点から、不織布を含むシート基材であることが好ましく、より好ましくは不織布である。上記不織布としては、スパンボンド不織布、スパンレース不織布、サーマルボンド不織布、ニードルパンチ不織布、スティッチボンド不織布などが挙げられる。 The sheet base material constituting the sheet-shaped cosmetic of the present invention is not limited, and is a sheet-shaped support that can be impregnated with the α-gel-containing composition of the present invention. As the sheet base material of the present invention, a woven fabric or a non-woven fabric is preferable. The sheet base material of the present invention may be a laminated body (that is, a laminated sheet), for example, a laminated body of a woven fabric, a laminated body of a non-woven fabric, a laminated body of a woven fabric and a non-woven fabric, and the like. The sheet base material of the present invention is preferably a sheet base material containing a non-woven fabric, and more preferably a non-woven fabric, from the viewpoint of improving usability, ease of processing, and the like. Examples of the non-woven fabric include spunbond non-woven fabric, spunlace non-woven fabric, thermal bond non-woven fabric, needle punch non-woven fabric, stitch bond non-woven fabric and the like.
上記織布や不織布を構成する繊維としては、限定されず、たとえば、天然繊維、合成繊維、半天然繊維などが挙げられる。上記天然繊維としては、綿、パルプ、シルク、セルロース、麻、リンター、カボックなどが挙げられる。上記合成繊維としては、ナイロン繊維、ポリエステル繊維（たとえば、ポリエチレンテレフタレート繊維、ポリブチレンテレフタレート繊維等）、アクリル繊維、ポリオレフィン繊維（たとえば、ポリプロピレン繊維、ポリエチレン繊維等）などが挙げられる。上記半天然繊維としては、レーヨン、アセテートなどが挙げられる。上記繊維は、１種のみを用いてもよいし、２種以上を用いてもよい。また、２種以上の上記繊維からなる混紡繊維を用いてもよい。 The fibers constituting the woven fabric or the non-woven fabric are not limited, and examples thereof include natural fibers, synthetic fibers, and semi-natural fibers. Examples of the natural fiber include cotton, pulp, silk, cellulose, hemp, linter, and cabock. Examples of the synthetic fiber include nylon fiber, polyester fiber (for example, polyethylene terephthalate fiber, polybutylene terephthalate fiber, etc.), acrylic fiber, polyolefin fiber (for example, polypropylene fiber, polyethylene fiber, etc.) and the like. Examples of the semi-natural fiber include rayon and acetate. Only one type of the fiber may be used, or two or more types may be used. Further, a blended fiber composed of two or more kinds of the above fibers may be used.
本発明のシート基材には、エンボス加工処理を施してもよい。上記エンボス加工処理としては、限定されず、たとえば、裏面を押し上げて浮かす（したがって裏面は凹む）方式や、表面に特殊なインクを付着することで凸部を形成する（裏面は凹まない）方式などが挙げられる。 The sheet base material of the present invention may be embossed. The embossing process is not limited to, for example, a method of pushing up the back surface to float (therefore the back surface is dented), a method of forming a convex portion by adhering a special ink to the front surface (the back surface is not dented), and the like. Can be mentioned.
本発明のシート基材の目付は、特に限定されないが、シート状化粧料の使用感を向上させる観点から、２０〜１５０ｇ／ｍ2が好ましく、４５〜１２５ｇ／ｍ2がより好ましく、更に好ましくは６０〜１００ｇ／ｍ2である。 The basis weight of the sheet base material of the present invention is not particularly limited, but is preferably 20 to 150 g / m 2 and more preferably 45 to 125 g / m 2 from the viewpoint of improving the usability of the sheet cosmetic. It is 60 to 100 g / m 2 .
本発明のシート基材は、織布や不織布等の種類に応じて、公知慣用の製造方法により製造することができる。また、本発明のシート基材には市販品を用いることもできる。市販品としては、限定されないが、たとえば、ダイワボウポリテック社製、商品名「ＲＨ」；ダイワボウポリテック社製、商品名「ＡＳ−４０」；フタムラ化学社製、商品名「ＴＣＦ４０４ＷＪ」；ユニチカ社製、商品名「コットエース Ａ０６０Ｓ／Ａ１８」；ユニチカ社製、商品名「コットエース Ｃ０３０Ｓ／Ａ１８」；クラレ社製、商品名「クラフレックスＪＰ２４４５Ｂ０１９」；クラレ社製、商品名「クラフレックスＪＰ０５０９Ｂ０５６」；クラレ社製、商品名「クラフレックスＪＰ４２５０Ｈ０２３」；旭化成社製、商品名「ベンリーゼＳＥ８０３」；旭化成社製、商品名「ベンリーゼＪＰ２５４」；旭化成社製、商品名「ベンリーゼＲＥ７５Ｋ」；三昭紙業社製、商品名「サンモアＳＰ８７４０」；三昭紙業社製、商品名「サンモアＳＰ８７４８」；伊野紙社製、商品名「Ｍ１−３０−２ＰＥ」などが挙げられる。 The sheet base material of the present invention can be produced by a known and commonly used production method depending on the type of woven fabric, non-woven fabric, or the like. A commercially available product can also be used as the sheet base material of the present invention. Commercially available products are not limited, for example, manufactured by Daiwa Bow Polytech, trade name "RH"; manufactured by Daiwa Bow Polytech, trade name "AS-40"; manufactured by Futamura Chemical Co., Ltd., trade name "TCF404WJ"; manufactured by Unitica, Product name "Cott Ace A060S / A18"; Made by Unitika, Product name "Cott Ace C030S / A18"; Made by Kuraray, Product name "Kuraflex JP2445B019"; Kurare, Product name "Kuraflex JP0509B056"; , Product name "Claflex JP4250H023"; Asahi Kasei Co., Ltd., Product name "Benlyse SE803"; Asahi Kasei Co., Ltd., Product name "Benlyse JP254"; Asahi Kasei Co., Ltd., Product name "Benlyse RE75K"; Sansho Paper Industry Co., Ltd. Product name "Sunmore SP8740"; manufactured by Sansho Paper Industry Co., Ltd., product name "Sunmore SP8748"; manufactured by Ino Paper Co., Ltd., product name "M1-30-2PE" and the like.
次に実施例を挙げて本発明を更に詳細に説明する。 Next, the present invention will be described in more detail with reference to examples.
実施例１〜３及び比較例１
表１組成のαゲル含有組成物を製造し、アルミパウチ内で表２組成のシート基材を浸漬させてフェイスマスクを得た。得られたフェイスマスクを顔全体に１０分間貼付した後、以下の評価を行った（実施例１〜３）。また同じ組成のαゲル含有組成物をそのまま顔全体に塗布した後、同じ評価を行った（比較例１）。その結果を表２に示す。
Examples 1 to 3 and Comparative Example 1
An α-gel-containing composition having the composition shown in Table 1 was produced, and a sheet substrate having the composition shown in Table 2 was immersed in an aluminum pouch to obtain a face mask. After applying the obtained face mask to the entire face for 10 minutes, the following evaluation was performed (Examples 1 to 3). Further, after applying the α-gel-containing composition having the same composition to the entire face as it was, the same evaluation was performed (Comparative Example 1). The results are shown in Table 2.
＊２：シリコーン ＫＦ−９６Ａ−１０ＣＳ（信越化学工業社製）
＊３：カーボポール ＥＴＤ２０２０ ＰＯＬＹＭＥＲ（Ｌｕｂｒｉｚｏｌ社製）
* 2: Silicone KF-96A-10CS (manufactured by Shin-Etsu Chemical Co., Ltd.)
* 3: Carbomer ETD2020 POLYMER (manufactured by Lubrizol)
（αゲル含有組成物の製造方法）
第I相の成分を、８０〜９５℃で加熱混合し、これにプロペラ攪拌下（３００ｒ
ｐｍ)、８０〜９５℃に加熱した第II相を加えて乳化し、２５℃まで徐々に冷却し
た後、第III相を加えて製造した。
(Method for producing α-gel-containing composition)
The components of Phase I are heated and mixed at 80 to 95 ° C., and the mixture is stirred with a propeller (300r).
pm), Phase II heated to 80-95 ° C. was added for emulsification, gradually cooled to 25 ° C., and then Phase III was added for production.
（評価方法）
（１）なじみやすさ：
専門パネラー１０名についてαゲル含有組成物を顔全体に塗布または１０分間貼付後、手で肌上に残った剤を円を描くようになじませ、摩擦感を感じるまでの時間を測定し、以下の基準で評価した。時間が短いほど、なじみやすいことを示す。
５：２分未満
４：２分以上〜３分未満
３：３分以上〜４分未満
２：４分以上〜５分未満
１：５分以上
(Evaluation method)
(1) Familiarity:
About 10 specialized panelists After applying the α-gel-containing composition to the entire face or applying it for 10 minutes, apply the agent remaining on the skin by hand in a circular motion and measure the time until a feeling of friction is felt. It was evaluated according to the criteria of. The shorter the time, the easier it is to get used to.
5: Less than 2 minutes 4: 2 minutes or more to less than 3 minutes 3: 3 minutes or more to less than 4 minutes 2: 4 minutes or more to less than 5 minutes 1: 5 minutes or more
（２）しっとり感：
専門パネラー１０名についてαゲル含有組成物を顔全体に塗布または１０分間貼付後、剤がなじみきった後のしっとり感を以下の基準で評価し、結果を平均値で示した。（小数点以下は四捨五入）
５：満足
４：やや満足
３：普通
２：あまり満足でない
１：満足でない
(2) Moist feeling:
After applying the α-gel-containing composition to the entire face or applying it for 10 minutes to 10 specialized panelists, the moist feeling after the agent was completely absorbed was evaluated according to the following criteria, and the results were shown as average values. (Rounded to the nearest whole number)
5: Satisfied 4: Slightly satisfied 3: Normal 2: Not very satisfied 1: Not satisfied
（３）パウダーファンデーション塗布後の、粉体の均一付着性
専門パネラー１０名についてαゲル含有組成物を顔全体に塗布または１０分間貼付後、剤がなじみきってから１分後にパウダーファンデーション（商品名「ソフィーナ プリマヴィスタ パウダーファンデーション」、花王社製）を塗布し、その仕上がり（粉体の均一付着性）を以下の基準で評価し、結果を平均値で示した。（小数点以下は四捨五入）
５：均一
４：やや均一
３：どちらともいえない
２：あまり均一でない
１：均一でない
(3) Uniform adhesion of powder after application of powder foundation About 10 specialist panelists After applying the α-gel-containing composition to the entire face or applying it for 10 minutes, powder foundation (trade name) 1 minute after the agent has become familiar. "Sofina Primavista Powder Foundation" (manufactured by Kao Co., Ltd.) was applied, and the finish (uniform adhesion of powder) was evaluated according to the following criteria, and the results were shown as average values. (Rounded to the nearest whole number)
5: Uniform 4: Slightly uniform 3: Neither can be said 2: Not very uniform 1: Not uniform
＊１）ベンリーゼＳＥ８０３；旭化成社製
＊２）含浸率とシート基材の坪量より単位面積当たりのαゲル含有組成物量を算出し、その算出した値とαゲル含有組成物中のαゲル量（成分Ａ〜Ｄの総量）より、単位面積当たりのαゲル量を算出した。
＊３）顔への移行量は、貼付前のフェイスマスク質量と顔に１０分間貼付後のフェイスマスク質量との差から算出した。（尚、貼付中の水分の揮発の影響を無くすよう、貼付したフェイスマスクの上をラップフィルムで覆う条件で、顔への移行量を算出している。）
* 1) Benlyse SE803; manufactured by Asahi Kasei Corporation * 2) Calculate the amount of α-gel-containing composition per unit area from the impregnation rate and the basis weight of the sheet base material, and the calculated value and the amount of α-gel in the α-gel-containing composition. The amount of α-gel per unit area was calculated from (total amount of components A to D).
* 3) The amount transferred to the face was calculated from the difference between the mass of the face mask before application and the mass of the face mask after application to the face for 10 minutes. (In addition, the amount of transfer to the face is calculated under the condition that the attached face mask is covered with a wrap film so as to eliminate the influence of volatilization of water during application.)
Claims (6)
（Ａ）グリセリンモノ脂肪酸エステル、ソルビタンモノ脂肪酸エステル、ソルビタンジ脂肪酸エステル、ソルビトールモノ脂肪酸エステル、ソルビトールジ脂肪酸エステル、ショ糖モノ脂肪酸エステル、及びグリセリンモノアルキルエーテルから選ばれる１種以上の化合物
（Ｂ）炭素数１４〜２２の高級アルコール、及びステロール類から選ばれる１種以上の化合物
（Ｃ）一般式（１）：
(A) One or more compounds selected from glycerin monofatty acid ester, sorbitan monofatty acid ester, sorbitandi fatty acid ester, sorbitol monofatty acid ester, sorbitol difatty acid ester, sucrose monofatty acid ester, and glycerin monoalkyl ether (B) One or more compounds selected from higher alcohols having 14 to 22 carbon atoms and sterols (C) General formula (1):
（Ｄ）ポリオキシエチレン基を有するＨＬＢ１０以上の非イオン界面活性剤、イオン性界面活性剤及びスフィンゴシン塩類から選ばれる１種以上の化合物、
（Ｅ）水 The sheet-shaped cosmetic according to claim 3, wherein the α-gel-containing composition further contains the following components (D) and (E).
(D) One or more compounds selected from HLB 10 or higher nonionic surfactants having a polyoxyethylene group, ionic surfactants and sphingosine salts,
(E) Water
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| JP2019109083A JP2020200283A (en) | 2019-06-11 | 2019-06-11 | Sheet-like cosmetics |
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