JP2012214469A - Emulsion composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an emulsion composition which gives a coated film having softness and elasticity, covers skin uniformly, having high moisture retention power and smoothness to skin and giving smooth look.SOLUTION: The emulsion composition, as an example, contains: (A) 0.001-10 mass% of glyceryl monobehenate or monocetyl glyceryl ether; (B) 0.001-10 mass% of cetanol or stearyl alcohol; (C) 0.001-15 mass% of ceramides; (D) 0.00025-10 mass% of stearoyl glutamate salt, stearoyl methyl taurinate salt or polyoxyethylene stearylether phosphate salt; (E) 0.001-6 mass% of (acrylic acid/alkyl acrylate(C10-30))copolymer, (alkyl acrylate/steareth-20 methacrylate)copolymer, laureth-13PG hydroxyethyl cellulose or stearoxy PG hydroxyethylcellulose sulfonate Na; and (F) water.

Description

  The present invention relates to an emulsified composition.

In the outermost stratum corneum of the skin, there are stratum corneum cells and intercellular lipids that fill the gaps. Most of them have an α-gel structure, which suppresses the invasion of substances from the outside and moisture evaporation from the inside, while at the same time holding the moisture itself, Has the function of maintaining a smooth appearance.
In general, it is known that an unfavorable skin condition is caused by a decrease in intercellular lipids, particularly ceramide, and supplementing ceramide with an external application is considered to lead to improvement in skin functional deterioration.

However, since ceramide has a high melting point and high crystallinity and is difficult to be blended into an external preparation or the like, various studies have been made on blending it stably.
For example, Patent Document 1 discloses that an emulsified composition in which ceramides, glycerin monofatty acid esters and higher alcohols are combined at a specific ratio forms an α-gel structure in which ceramide crystal precipitation is suppressed and moisture is easily retained. In addition, it is described that the moisturizing effect is high.
Further, by further combining a specific sugar alcohol or a disaccharide or a trisaccharide, the water retention ability of the α-gel can be further increased, and moisture can remain on the skin for a long time, thereby improving the skin condition. Are also being studied (Patent Documents 2 and 3).

However, although these compositions form an α-gel structure, they are low in viscosity and difficult to apply to the skin, so even if a film having a moisturizing effect is formed, the film is brittle and can uniformly cover the skin. Therefore, it was difficult to exhibit sufficient water retention ability.
Further, since the film lacks flexibility and elasticity, the skin after application has a unique squeaky feeling and rough feeling, and a good feeling of use cannot be obtained. Furthermore, there is a problem that the appearance is not smooth after application and the effect of improving the appearance of the skin cannot be obtained.

JP 2007-22997 A JP 2011-32265 A JP 2011-32266 A

  The present invention provides an emulsified composition in which the coating film has flexibility and elasticity, can uniformly cover the skin, has a high moisture retention ability, has a smooth skin feel, and can also have a smooth appearance. Is.

  The inventors of the present invention can obtain an elastic liquid property with high viscosity by combining a specific water-soluble polymer with an α-gel designed to increase moisture retention, and the coating film has flexibility and elasticity. Therefore, it has been found that an emulsified composition can be obtained that can uniformly cover the skin, enhances moisture retention, has a smooth skin feel, and can have a smooth appearance.

The present invention includes the following components (A), (B), (C), (D) and (F1):
(A) The following general formula (1)

(In the formula, Z ¹ represents a structure having two or more hydroxyl groups in a glycerin, sorbitan, sorbitol or sucrose residue, Y ¹ represents an ester bond group or an ether bond group, and R represents the number of carbon atoms. 14 represents a hydrocarbon group of 22 to 22 and n represents a number of 1 to 4)
0.001 to 10% by mass of a compound represented by
(B) one or more compounds selected from higher alcohols having 14 to 22 carbon atoms and sterols 0.001 to 10% by mass,
(C) General formula (2):

(Wherein R ¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 4 to 30 carbon atoms which may be substituted by a hydroxyl group, a carbonyl group or an amino group; A methylene group, a methine group or an oxygen atom; X ¹ , X ² and X ³ each independently represents a hydrogen atom, a hydroxyl group or an acetoxy group, and X ⁴ represents a hydrogen atom, an acetyl group or a glyceryl group, Combined with the adjacent oxygen atom to form an oxo group (provided that when Z is a methine group, ^one of X ¹ and X ² is a hydrogen atom and the other does not exist. X ⁴ represents an oxo group. When formed, X ³ is not present.); R ² and R ³ each independently represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an acetoxymethyl group; R ⁴ represents a hydroxyl group, a carbonyl group or an amino group. Replace A linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 60 carbon atoms which may have an ether bond, an ester bond or an amide bond in the main chain; ⁵ represents a hydrogen atom, or may have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group, and is a linear or branched saturated or unsaturated group having 1 to 30 carbon atoms in total A compound represented by the following formula: 0.001 to 15% by mass;
(D) Anionic surfactant 0.00025-10 mass%,
(F1) Water phase I containing water
Are mixed, emulsified, and cooled, after step 1,
(E) Step 2 of further mixing water-soluble polymer 0.001 to 6% by mass selected from alkyl-modified polyacrylic acid vinyl polymer and alkyl-modified polysaccharide polymer, and (F2) water phase II containing water
The manufacturing method of an emulsion composition provided with this is provided.

The present invention also includes the following components (A), (B), (C), (D), (E) and (F):
(A) glyceryl monobehenate or monocetyl glyceryl ether 0.001 to 10% by mass,
(B) cetanol or stearyl alcohol 0.001 to 10% by mass,
(C) Ceramides represented by general formula (3) or general formula (4) 0.001 to 15% by mass,

(Wherein R ¹¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 7 to 19 carbon atoms which may be substituted by a hydroxyl group; Z ¹ represents a methylene group or a methine group; X ⁵ , X ⁶ and X ⁷ each independently represents a hydrogen atom, a hydroxyl group or an acetoxy group; X ⁸ represents a hydrogen atom or together with an adjacent oxygen atom, forms an oxo group. (However, when Z ¹ is a methine group, ^one of X ⁵ and X ⁶ is a hydrogen atom and the other does not exist. When X ⁸ forms an oxo group, X ⁷ does not exist.); R ¹² represents a hydroxymethyl group or an acetoxymethyl group; R ¹³ represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; R ¹⁴ has 5 to 30 carbon atoms which may be substituted by a hydroxyl group Whether it is a linear, branched or cyclic saturated or unsaturated hydrocarbon group Or a linear or branched saturated or unsaturated fatty acid having 8 to 22 carbon atoms which may be substituted with a hydroxyl group at the ω-terminal of the alkyl group; Indicates that it may be a bond.)

(In the formula, R ¹⁵ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom having 10 to 22 carbon atoms which may be substituted with a hydroxyl group; X ⁹ represents a hydrogen atom; , An acetyl group or a glyceryl group; R ¹⁶ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 22 carbon atoms which may be substituted with a hydroxyl group or an amino group; Or a hydrocarbon group having an ester bond with a linear or branched saturated or unsaturated fatty acid having 8 to 22 carbon atoms which may be substituted with a hydroxyl group at the ω-terminal; R ¹⁷ represents a hydrogen atom; Or a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an acetoxy group which may be substituted is an alkyl group having 1 to 30 carbon atoms in total.
(D) stearoyl glutamate, stearoyl methyl taurate or polyoxyethylene stearyl ether phosphate 0.00025-10 mass%,
(E) (acrylic acid / alkyl acrylate (C10-30)) copolymer, (alkyl acrylate / steareth methacrylate-20) copolymer, laureth-13PG hydroxyethyl cellulose or stearoxy PG hydroxyethyl cellulose sulfonate 0.001-6 mass %,
(F) An emulsified composition containing water is provided.

  The emulsified composition of the present invention has a high viscosity and an elastic liquid property, and since the coating film has flexibility and elasticity, it can uniformly cover the skin, has a high moisture retention ability, and has a smooth skin feel. And you can make it look smooth.

The component (A) used in the present invention is represented by the general formula (1).
In the formula, the hydrocarbon group having 14 to 22 carbon atoms represented by R is preferably a linear hydrocarbon group, for example, a linear alkyl group such as a myristyl group, a palmityl group, a stearyl group, a behenyl group; a palmitoyl group; An oleyl group etc. are mentioned.
Examples of the compound represented by the general formula (1) include glycerin monofatty acid ester, sorbitan monofatty acid ester, sorbitan difatty acid ester, sorbitol monofatty acid ester, sorbitol difatty acid ester, sucrose monofatty acid ester, glycerin monoalkyl ether, and the like. Can be mentioned.

  As the component (A), glycerin monofatty acid ester, sorbitan monofatty acid ester, and glycerin monoalkyl ether are preferable. Among them, glyceryl monopalmitate, glyceryl monostearate, glyceryl monobehenate, sorbitan monostearate, monocetyl glyceryl ether, and monostearyl glyceryl ether are preferable, and further, a lamellar film-forming property and water retention described later are improved. From the viewpoint, glyceryl monobehenate or monocetyl glyceryl ether is more preferable.

  One or more types of component (A) can be used, and 0.001-10 mass% is contained in the whole composition, Preferably it is 0.05-7 mass%, More preferably, it is 0.25-3 mass%. Contained. Within this range, after applying the emulsion composition of the present invention to the skin, a lamellar film in which lipid layers and water layers composed of components (B) to (E) described later are alternately arranged on the skin surface during the drying process Can be formed. As a result, moisture can be retained between the layers, so that the moisture retention ability is increased, which is preferable. Furthermore, the feeling of use of the coating film is improved, which is preferable.

Among the components (B) used in the present invention, the higher alcohol has 14 to 22 carbon atoms, preferably 16 to 18 carbon atoms. For example, myristyl alcohol, cetanol, stearyl alcohol, behenyl alcohol and the like can be mentioned.
Of these, cetanol and stearyl alcohol are preferable, and cetanol is more preferable.

  Moreover, cholesterol and phytosterol are mentioned as a sterol among components (B). Phytosterol is a general term for plant sterols such as β-sitosterol, campesterol, stigmasterol, and brassicasterol, and the composition thereof is not limited.

  One or more types of component (B) can be used, and 0.001 to 10% by mass is contained in the total composition, preferably 0.05 to 7% by mass, and more preferably 0.1 to 3% by mass. Is done. Within this range, after applying the emulsified composition of the present invention to the skin, the lipid layer and moisture constituted by the aforementioned component (A) and components (C) to (E) described later on the skin surface in the drying process A lamellar film with alternating layers can be formed. As a result, moisture can be retained between the layers, which is preferable since moisture blockage is enhanced. Furthermore, the appearance of the skin after application is also improved, which is preferable.

  The ceramide of component (C) used in the present invention is represented by the general formula (2).

In the formula, R ¹ is a straight chain having 4 to 30 carbon atoms, preferably a hydroxyl group 7 to 22 carbon atoms which may be substituted by a hydroxyl group, a carbonyl group or an amino group, A branched or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom.
Z represents a methylene group, a methine group or an oxygen atom.

X ¹ , X ² and X ³ each independently represent a hydrogen atom, a hydroxyl group or an acetoxy group. It is preferable that 0 to ^{1 of} X ¹ , X ² and X ³ are hydroxyl groups and the remainder is a hydrogen atom. When Z is a methine group, only ^one of X ¹ and X ² is a hydrogen atom, and the other does not exist. X ⁴ is preferably a hydrogen atom or a glyceryl group.
R ² and R ³ represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an acetoxymethyl group, preferred R ² is a hydrogen atom or a hydroxymethyl group, and preferred R ³ is a hydrogen atom.

R ⁴ is a linear, branched or branched chain having 5 to 60 carbon atoms which may have an ether bond, an ester bond or an amide bond in the main chain, which may be substituted with a hydroxyl group, a carboxy group or an amino group. A cyclic saturated or unsaturated hydrocarbon group is shown. Preferably, the hydroxyl group or amino group may be substituted a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 35 carbon atoms, or a hydroxyl group at the ω position of the hydrocarbon group In which a linear, branched, or cyclic saturated or unsaturated fatty acid having 8 to 22 carbon atoms, which may be substituted, is an ester bond or an amide bond. As the fatty acid to be bonded, isostearic acid, 12-hydroxystearic acid or linoleic acid is preferable.

R ⁵ represents a hydrogen atom, or may have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group, and an acetoxy group. It is a saturated hydrocarbon group. When R ¹ is a hydrogen atom and Z is an oxygen atom, R ⁵ is a hydrocarbon group having 10 to 30 carbon atoms in total. When R ¹ is a hydrocarbon group, R ⁵ is a hydrocarbon group having 1 to 8 carbon atoms in total. Of these, a hydrogen atom, or a hydrocarbon group having 1 to 8 carbon atoms in total, which may be substituted with 1 to 3 groups selected from a hydroxyl group, a hydroxyalkoxy group, and an alkoxy group, is preferable. Here, as a hydroxy alkoxy group and an alkoxy group, a C1-C7 thing is preferable.

As the compound represented by the general formula (2), ceramides represented by the following general formula (3) or (4) are preferable.
(I) The compound represented by the general formula (3) may be a naturally-occurring ceramide or a synthetic product having the same structure.

(Wherein R ¹¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 7 to 19 carbon atoms which may be substituted by a hydroxyl group; Z ¹ represents a methylene group or a methine group; X ⁵ , X ⁶ and X ⁷ each independently represents a hydrogen atom, a hydroxyl group or an acetoxy group; X ⁸ represents a hydrogen atom or together with an adjacent oxygen atom, forms an oxo group. (However, when Z ¹ is a methine group, ^one of X ⁵ and X ⁶ is a hydrogen atom and the other does not exist. When X ⁸ forms an oxo group, X ⁷ does not exist.); R ¹² represents a hydroxymethyl group or an acetoxymethyl group; R ¹³ represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; R ¹⁴ has 5 to 30 carbon atoms which may be substituted by a hydroxyl group Whether it is a linear, branched or cyclic saturated or unsaturated hydrocarbon group Or a linear or branched saturated or unsaturated fatty acid having 8 to 22 carbon atoms which may be substituted with a hydroxyl group at the ω-terminal of the alkyl group; Indicates that it may be a bond.)

Preferably, R ¹¹ is a linear alkyl group having 7 to 19 carbon atoms, more preferably 13 to 15 carbon atoms; R ¹⁴ is a linear alkyl group having 9 to 27 carbon atoms that may be substituted by a hydroxyl group, or linoleic acid Is a straight-chain alkyl group having 9 to 27 carbon atoms with an ester bond. X ⁸ preferably represents a hydrogen atom or forms an oxo group together with an oxygen atom. Further, R ¹⁴ is preferably tricosyl, 1-hydroxypentadecyl, 1-hydroxytricosyl, heptadecyl, 1-hydroxyundecyl, or a nonacosyl group in which linoleic acid is ester-bonded to the ω position.

  Specific examples of natural ceramides include ceramides Type 1 to 7 in which sphingosine, dihydrosphingosine, phytosphingosine or sphingadienin is amidated (for example, J. Lipid Res., 24: 759 (1983), FIG. And porcine and human ceramides described in FIG. 4 of J. Lipid. Res., 35: 2069 (1994)).

Furthermore, these N-alkyl bodies (for example, N-methyl body) are also included.
These ceramides may be either natural (D (−)) optically active or non-natural (L (+)) optically active, or a mixture of natural and nonnatural. May be used. The relative configuration of the above compound may be a natural configuration, a non-natural configuration other than that, or a mixture thereof. Of these, compounds of CERAMIDE1, CERAMIDE2, CERAMIDE3, CERAMIDE5, CERAMIDE6II (hereinafter referred to as INCI, 8th Edition) and those represented by the following formula are preferable.

These may be any of natural extracts and synthetic products, and commercially available products can be used.
Such commercially available natural ceramides are Ceramide I, Ceramide III, Ceramide IIIA, Ceramide IIIB, Ceramide IIIC, Ceramide VI (above, Cosmo Farm), Ceramide TIC-001 (Takasago Inc.), CERAMIDE II (Quest International), DS-Ceramide VI, DS-CLA-Phytoceramide, C6-Phytoceramide, DS-ceramide Y3S (DOOSAN), CERAMIDE2 (Cedama).

(II) A pseudo-ceramide represented by the general formula (4).

(In the formula, R ¹⁵ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom having 10 to 22 carbon atoms which may be substituted with a hydroxyl group; X ⁹ represents a hydrogen atom; , An acetyl group or a glyceryl group; R ¹⁶ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 22 carbon atoms which may be substituted with a hydroxyl group or an amino group; Or a hydrocarbon group having an ester bond with a linear or branched saturated or unsaturated fatty acid having 8 to 22 carbon atoms which may be substituted with a hydroxyl group at the ω-terminal; R ¹⁷ represents a hydrogen atom; Or a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an acetoxy group which may be substituted is an alkyl group having 1 to 30 carbon atoms in total.

R ¹⁶ includes nonyl, tridecyl, pentadecyl, an undecyl group in which linoleic acid is ester-bonded to the ω-position, a pentadecyl group in which linoleic acid is ester-bonded to the ω-position, a pentadecyl group in which 12-hydroxystearic acid is ester-bonded to the ω-position, An undecyl group in which methyl branched isostearic acid is amide-bonded at the ω position is preferred.

R ¹⁷ is an alkyl having a total carbon number of 10 to 30, preferably a total carbon number of 12 to 20, which may be substituted by a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an acetoxy group when R ¹⁵ is a hydrogen atom. When R ¹⁵ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 10 to 22 carbon atoms which may be substituted with a hydroxyl group, What shows a C1-C8 alkyl group which the hydroxyl group, the hydroxy alkoxy group, an alkoxy group, or an acetoxy group may substitute is preferable. As the hydroxyalkoxy group or alkoxy group for R17, those having 1 to 7 carbon atoms are preferred.

In general formula (4), R ¹⁵ is a hexadecyl group, X ⁹ is a hydrogen atom, R ¹⁶ is a pentadecyl group, R ¹⁷ is a hydroxyethyl group; R ¹⁵ is a hexadecyl group, X ⁹ is a hydrogen atom, and R ¹⁶ is R ¹⁶ Preferred are pseudoceramides having a nonyl group, R ¹⁷ is a hydroxyethyl group; or R ¹⁵ is a hexadecyl group, X ⁹ is a glyceryl group, R ¹⁶ is a tridecyl group, and R ¹⁷ is a 3-methoxypropyl group. 4) R ¹⁵ is a hexadecyl group, X ⁹ is a hydrogen atom, R ¹⁶ is a pentadecyl group, and R ¹⁷ is a hydroxyethyl group (N- (hexadecyloxyhydroxypropyl) -N-hydroxyethylhexadecanamide). More preferred.

  The compound of component (C) can use 1 or more types, 0.001-15 mass% is contained in the whole composition, Preferably it is 0.05-7 mass%, More preferably, it is 0.5-5 mass. % Content. If it is in this range, after apply | coating the emulsion composition of this invention to skin, the above-mentioned component (A), (B) and the component (D)-(E) mentioned later comprise on the skin surface in the drying process. A lamellar film in which lipid layers and moisture layers are alternately arranged can be formed. As a result, moisture can be retained between the layers. In addition, a component (C) does not crystallize in the emulsion composition of this invention and the lamellar-like film | membrane formed after application | coating drying. As a result, the component (C) is preferable because it can be highly penetrated into the skin. Furthermore, it is preferable because it improves the appearance and feel of use after application.

  Examples of the anionic surfactant of component (D) used in the present invention include fatty acid salts having 12 to 24 carbon atoms such as sodium laurate, potassium palmitate and arginine stearate; alkyl such as sodium lauryl sulfate and potassium lauryl sulfate. Sulfate ester salt; alkyl ether sulfate ester salt such as polyoxyethylene lauryl sulfate triethanolamine; N-acyl sarcosine salt such as lauroyl sarcosine sodium; N-stearoyl-N-methyltaurine sodium, N-myristoyl-N-methyltaurine sodium Fatty acid amide sulfonates such as sodium monostearyl phosphate, etc .; Polyoxyethylene oleyl ether sodium phosphate, polyoxyethylene stearyl ether sodium phosphate, etc. Siethylene alkyl ether phosphate; long-chain sulfosuccinate such as sodium di-2-ethylhexylsulfosuccinate; monosodium N-lauroyl glutamate, sodium N-stearoyl-L-glutamate, arginine N-stearoyl-L-glutamate, N -Long-chain N-acyl glutamate such as sodium stearoyl glutamate and sodium N-myristoyl-L-glutamate.

Among these, C12-24 fatty acid salt, alkyl sulfate ester salt, alkyl ether sulfate ester salt, fatty acid amide sulfonate, alkyl phosphate, polyoxyethylene alkyl ether phosphate, long-chain N-acyl glutamic acid Salts are preferred.
Among them, stearoyl glutamate, stearoyl methyl taurate, and polyoxyethylene stearyl ether phosphate are preferable, stearoyl glutamate and stearoyl methyl taurate are more preferable, and stearoyl glutamate is more preferable.
The salt of component (D) is preferably one or more selected from sodium salts, potassium salts, basic amino acid salts, and ammonium, and one selected from sodium salts and arginine salts from the viewpoint of developing the viscosity of the emulsion composition. The above is preferable.

  Component (D) can be blended as an acid, neutralized with a base, and contained as a salt. The base for neutralizing component (D) in this case is preferably one or more selected from basic amino acids, sodium hydroxide, potassium hydroxide, triethanolamine, and calcium hydroxide. One or more selected from arginine, lysine and histidine are preferred. As a base which neutralizes a component (D), 1 type or 2 types chosen from arginine and sodium hydroxide from a viewpoint of expression of the viscosity of an emulsion composition are preferable, and arginine is more preferable from points, such as a usability | use_condition.

  One or more types of component (D) can be used, and 0.00025-10 mass% is contained in the whole composition, preferably 0.05-2 mass%, more preferably 0.1-1 mass%. Is done. If it exists in this range, component (A)-(C) can be emulsified. Furthermore, after applying the emulsified composition of the present invention to the skin, a lamellar film in which lipid layers and water layers composed of the components (A) to (D) and the component (E) are alternately arranged on the skin surface in the drying process is formed. Can be formed. As a result, moisture can be retained between the layers, which is preferable because it helps improve moisture retention.

Component (E) used in the present invention is a water-soluble polymer selected from alkyl-modified polyacrylic acid polymers and alkyl-modified polysaccharide polymers.
Examples include alkyl acrylate copolymers, (meth) acrylic acid / (meth) acrylic acid alkyl copolymers, alkyl acrylate / alkyl methacrylate / polyoxyethylene stearyl ether copolymers, polysaccharide derivatives, and the like.
More specifically, (acrylic acid / alkyl acrylate (C10-30)) copolymer, (alkyl acrylate / methacrylic acid steareth-20) copolymer, laureth-13PG hydroxyethyl cellulose, stearoxy PG hydroxyethyl cellulose sulfonate Na and the like are preferable. .
Commercially available products include, for example, alkyl acrylate polymers such as Aculin 33 (The Dow Chemical Company) and (meth) acrylic acid / (meth) acrylate alkyl copolymers such as Pemlen TR-1 and Pemlen TR. -2, Carbopol ETD2020 (Lubricol Advanced Materials, Inc.) and the like. Further, examples of the alkyl acrylate / alkyl methacrylate / polyoxyethylene stearyl ether copolymer include Aculin 22 (The Dow Chemical Company). Examples of polysaccharide derivatives include SPS-S-SA, Sofcare EP-S (above, Kao Corporation), Natrosol Plus (Hercules-Aqualon) and the like.

  One or more types of component (E) can be used, and 0.001 to 6% by mass is contained in the total composition, preferably 0.05 to 5% by mass, more preferably 0.1 to 3% by mass. Is done. Within this range, the storage stability of the emulsion composition of the present invention can be improved. Furthermore, crystallization of the lipid mixture composed of the components (A) to (D) can be suppressed. As a result, after applying the emulsified composition of the present invention, flexibility can be imparted to the lamellar film formed on the skin surface in the drying process. As a result, it is preferable because it is useful for improving the water retention ability / use feeling / appearance of the skin after application.

  In this invention, the water of a component (F) comprises the remainder of each component, and it is preferable that 49-85 mass% and also 55-80 mass% are contained in the whole composition.

In the present invention, the mass ratio of the components (A), (B), (C), (D) and (E) is (E) / ((A) + (B) + (C)) = 0. It is preferably from 0025 to 50, more preferably from 0.01 to 3, and particularly preferably from 0.1 to 1.5 in that a high viscosity and elastic liquid property can be obtained. As a result, when applied to the skin, a high feeling of application can be felt and a good feeling of use can be imparted.
Further, (E) / (D) = 0.025 to 100, more preferably 0.14 to 7.5, particularly 1.2 to 6 is preferable in order to obtain a film having flexibility and elasticity.

  In the present invention, it is more preferable to combine the preferred components and the preferred contents of the components.

Furthermore, in the emulsion composition of the present invention,
Component (A) is glyceryl monobehenate or monocetyl glyceryl ether,
Component (B) is cetanol or stearyl alcohol,
A compound in which component (C) is represented by formula (1);
Component (D) is stearoyl glutamate, stearoyl methyl taurate or polyoxyethylene stearyl ether phosphate,
Component (E) is an (acrylic acid / alkyl acrylate (C10-30)) copolymer, (alkyl acrylate / stealeth methacrylate-20) copolymer, laureth-13PG hydroxyethyl cellulose or stearoxy PG hydroxyethyl cellulose sulfonate Na,
It is preferred that component (F) is water.

Furthermore, in the emulsion composition of the present invention,
Component (A) is glyceryl monobehenate,
Component (B) is cetanol,
A compound in which component (C) is represented by formula (1);
Component (D) is stearoyl glutamate,
Component (E) is an (acrylic acid / alkyl acrylate (C10-30)) copolymer, (alkyl acrylate / stealeth methacrylate-20) copolymer, laureth-13PG hydroxyethyl cellulose or stearoxy PG hydroxyethyl cellulose sulfonate Na,
It is preferred that component (F) is water.

  In the present invention, components (A) to (D) form an emulsion lipid. When these are dried, crystallization occurs, forming a hard and brittle film, and a film with high moisture retention cannot be obtained. However, by further containing the component (E), lipid crystallization is suppressed, and a lamellar flexible film containing a large amount of water and alternately arranging lipid layers and water layers may be formed. all right. In particular, when cetanol is used as the component (B), the flexibility of the film increases and the smoothness of the appearance and feel of the skin is improved. Further, the use of the emulsified composition of the present invention for the manufacture of a skin coating agent, the use of the emulsified composition of the present invention for the manufacture of a skin moisture retaining agent, and the manufacture of a coating film forming agent on the skin The use of the emulsified composition of the present invention can be provided.

  The emulsion composition of the present invention can further contain an oily component other than the components (B) and (C). For example, hydrocarbon oils such as liquid paraffin, squalane and petrolatum; ether oils such as cetyldimethylbutyl ether, ethylene glycol dioctyl ether and glycerol monooleyl ether; octyldodecyl myristate, isopropyl palmitate, butyl stearate, di-2 adipate -Ester oils such as ethylhexyl, neopentyl glycol dicaprate and trioctanoin; higher fatty acids such as stearic acid, behenic acid and isomyristinic acid; vegetable oils such as olive oil; dimethylpolysiloxane, cyclic dimethylpolysiloxane, methylphenylpolysiloxane, Amino-modified silicone, carboxy-modified silicone, alcohol-modified silicone, alkyl-modified silicone, polyether-modified silicone, fluorine-modified silicone, etc. Corn oil; perfluoroalkylethyl phosphoric acid, perfluoroalkyl polyoxyethylene phosphoric acid, a perfluoropolyether, such as fluorine-based oils such as polytetrafluoroethylene. These oil components are preferably contained in the total composition in an amount of 0 to 20% by mass.

  The emulsified composition of the present invention is an active ingredient or additive used in normal cosmetics, for example, water-soluble vitamins such as ascorbic acid, nicotinic acid amide, and nicotinic acid; buckwheat extract, licorice extract, aloe extract, Animal and plant extracts such as horse chestnut extract, tea extract, cucumber extract, clove extract, carrot extract, cranberry extract, placenta extract, seaweed extract, maronier extract, yuzu extract, asunaro extract, royal jelly extract, eucalyptus extract, asunaro extract; Bases such as potassium hydroxide, sodium hydroxide, triethanolamine and sodium carbonate; acids such as citric acid, tartaric acid, lactic acid, phosphoric acid, succinic acid and adipic acid can also be contained.

  The method for producing an emulsified composition of the present invention comprises the steps (1) of (1) in which the aqueous phase I containing the components (A) to (D) and a part (F1) of the component (F) is mixed and emulsified and cooled. It is preferable to further comprise a step of further mixing the aqueous phase component (aqueous phase II) containing (E) and the remainder (F2) of component (F). This method is preferable because an emulsion having excellent stability can be obtained in a wide temperature range by allowing the polymer to interact after forming the α-gel structure.

  Step 1 is a step of forming an α-gel structure, and a step selected from the following four manufacturing steps 1A, 1B, 1C, and 1D is preferable. From the viewpoint of manufacturability, a step selected from Step 1A and Step 1C comprising a step of neutralizing an unneutralized component (D) with a base is preferable. A step selected from Step 1A and Step 1B in which is mixed is preferable. As described above, step 1 preferably includes a step selected from step 1A, step 1B, and step 1C, more preferably includes step 1A or step 1B, and further preferably includes step 1A.

Step 1A: A step of obtaining a mixed component of an oil phase containing components (A), (B), (C) and an unneutralized component (D), and a part of the component (F) (F1) in the oil phase And a step of mixing and emulsifying the aqueous phase I containing the base and cooling.
Step 1B: A step of obtaining a mixed component of the oil phase containing the salts of components (A), (B), (C) and component (D), and a part (F1) of component (F) is included in the oil phase A step comprising mixing, emulsifying and cooling the aqueous phase I.
Step 1C: a step of obtaining a mixed component of an oil phase containing components (A), (B) and (C), an unneutralized component (D) in the oil phase, a part of component (F) (F1) And the aqueous phase I containing the base is mixed and emulsified and cooled.
Step 1D: A step of obtaining a mixed component of an oil phase containing components (A), (B) and (C), and a salt of component (D) and a part (F1) of component (F) are included in the oil phase A step comprising mixing, emulsifying and cooling the aqueous phase I.

  In these methods, water of component (F) is added and mixed separately in (F1) and (F2), and the mass ratio is (F1) / (F2) = 0.1-9, It is preferable that it is 0.25-4.

  The obtained emulsified composition is α-gel (α-type crystal), and precipitation of crystals (γ-type crystal) is suppressed. The α-gel can be confirmed by structural analysis by X-ray. The α-type structure is a hexagonal system, and the lipophilic group is oriented at right angles to the surface of the hydrophilic base layer, and a sharp diffraction peak appears at a Bragg angle of 21-23 °. is there.

The emulsified composition preferably has a viscosity at 25 ° C. of 10 to 8000 dPa · s, 500 to 1500 dPa · s, and more preferably 1500 to 5000 dPa · s. The emulsified composition of the present invention can be obtained as a highly viscous and elastic liquid by combining the above components.
In the present invention, the viscosity is measured at 25 ° C. with a B8R type rotational viscometer (rotor C or D, 5 r / min, measured for 1 minute).

  Moreover, the obtained emulsion composition is an oil-in-water emulsion composition, and is suitable, for example, as cosmetics such as skin lotion, emulsion, cream, and gel, and as a skin external preparation. In relation to the above-described embodiment, the present invention further discloses a method for using the emulsified composition described below and its application.

Use of an emulsified composition containing components (A), (B), (C), (D), (E) and (F) for the production of a coating film forming agent on the skin.
Use of the emulsion composition containing component (A), (B), (C), (D), (E) and (F) for manufacture of a skin external preparation.
An oil-in-water emulsion composition for forming a coating film on the skin, comprising components (A), (B), (C), (D), (E) and (F).

Examples 1-10 and Comparative Examples 1-7
The oil-in-water emulsion compositions having the compositions shown in Tables 1 and 2 were produced, and the viscosity and the residual water content were measured. The film was confirmed for the lamellar structure by SAXS and observed for the surface state by SEM. In addition, sensory evaluation was made on the persistence of moisture, the feel and appearance of the skin after application. The results are shown in Table 1 and Table 2 together.

(Production method)
The ingredients of phase I were heated and mixed at 80 to 90 ° C., and the ingredients of phase II heated to 80 to 90 ° C. were added to the mixture while stirring with a propeller (300 rpm). The mixture was emulsified under shearing conditions to form an α-gel. After gradually cooling to 25 ° C., the phase III component was added to obtain an oil-in-water emulsion composition.

(Evaluation method)
(1) Viscosity:
At 25 ° C., it was measured with a B8R type rotational viscometer (rotor C or D, 5 r / min, measured for 1 minute).

(2) Residual moisture content:
1 g of an oil-in-water emulsion composition is spread uniformly on a 6 × 6 cm metal tray at a constant thickness, and mass change is plotted against time under constant temperature and humidity of 20 ° C. and humidity of 40%. By forming a lamellar film over time, the mass change thereafter becomes extremely small. The residual water content 24 hours after the mass became constant was determined, and the water content relative to the solid content in the preparation was determined by the following formula. The solid content includes all components (A) to (E).

(3) Confirmation of lamellar structure by SAXS:
After artificially extending the oil-in-water emulsion composition at 0.001 g / cm ² and drying it for 1 day on an artificial leather Saplare (registered trademark), the state of the film surface was changed to Nano-viewer, λCuKα = 1.54 mm, Measurement was performed within 30 minutes of irradiation, camera length of 649.5 mm, and 2θ = 0.2 to 5 °.

(4) Observation of the surface state of the film by SEM:
After artificially spreading an oil-in-water emulsified composition at 0.001 g / cm ² on an artificial leather Saplare (registered trademark) and drying it for one day, the state of the film surface was magnified by SEM (scanning electron microscope). Observed at 50 times. The results are shown by the following criteria.
○: The boundary between the skin and the skin groove is smooth.
Δ: The boundary part of the skin hill / skin groove is turned up.
X: No film was formed.

(5) Persistence of moisture, skin feel after application (smoothness) and appearance (smooth appearance):
Twelve professional panelists applied “smooth skin feel” and “smooth skin appearance” immediately after 0.4 to 0.6 g of each oil-in-water emulsion composition was applied to the face, and 10 hours of application. The sensory evaluation of “sustainability of moisture” after the lapse was made. The results are shown as the number of panelists rated as “good”.

Examples 11-29 and Comparative Examples 8-9
In the same manner as in Examples 1 to 10, oil-in-water emulsion compositions having the compositions shown in Tables 3 to 6 were produced, the viscosity and the residual water content were measured, and the film was confirmed for the lamellar structure by SAXS and The surface state was observed by SEM. Moreover, the persistence of moisture, the feeling of the skin after application | coating, and the external appearance were evaluated. The results are shown in Tables 3 to 6.

Example 1, 30-32
In the same manner as in Examples 1 to 10, an oil-in-water emulsion composition having the composition shown in Table 7 was produced, and the viscosity and residual water content were measured. The film was checked for lamella structure by SAXS and surface by SEM. The state was observed. Moreover, the persistence of moisture, the feeling of the skin after application | coating, and the external appearance were evaluated. The results are also shown in Table 7.

  Examples 1 and 30 were manufactured by manufacturing process 1A, Example 31 was manufactured by manufacturing process 1C, and Example 32 was manufactured by manufacturing process 1D. Example 1 and Example 30 produced by blending the non-neutralized component (D) in the oil phase and produced by the production process 1A have high evaluation of the smoothness of the skin feel after application, and the crystallization of ceramide is suppressed. A lamella structure is confirmed, a result with a high moisturizing effect is obtained, and a high viscosity is obtained.

Claims (13)

The following components (A), (B), (C), (D) and (F1):
(A) The following general formula (1)

(In the formula, Z ¹ represents a structure having two or more hydroxyl groups in a glycerin, sorbitan, sorbitol or sucrose residue, Y ¹ represents an ester bond group or an ether bond group, and R represents the number of carbon atoms. 14 represents a hydrocarbon group of 22 to 22 and n represents a number of 1 to 4)
0.001 to 10% by mass of a compound represented by
(B) one or more compounds selected from higher alcohols having 14 to 22 carbon atoms and sterols 0.001 to 10% by mass,
(C) General formula (2):

(Wherein R ¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 4 to 30 carbon atoms which may be substituted by a hydroxyl group, a carbonyl group or an amino group; A methylene group, a methine group or an oxygen atom; X ¹ , X ² and X ³ each independently represents a hydrogen atom, a hydroxyl group or an acetoxy group, and X ⁴ represents a hydrogen atom, an acetyl group or a glyceryl group, Combined with the adjacent oxygen atom to form an oxo group (provided that when Z is a methine group, ^one of X ¹ and X ² is a hydrogen atom and the other does not exist. X ⁴ represents an oxo group. When formed, X ³ is not present.); R ² and R ³ each independently represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an acetoxymethyl group; R ⁴ represents a hydroxyl group, a carbonyl group or an amino group. Replace A linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 60 carbon atoms which may have an ether bond, an ester bond or an amide bond in the main chain; ⁵ represents a hydrogen atom, or may have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group, and is a linear or branched saturated or unsaturated group having 1 to 30 carbon atoms in total A compound represented by the following formula: 0.001 to 15% by mass;
(D) Anionic surfactant 0.00025-10 mass%,
(F1) Water phase I containing water
Are mixed, emulsified, and cooled, after step 1,
(E) Step 2 of further mixing water-soluble polymer 0.001 to 6% by mass selected from alkyl-modified polyacrylic acid vinyl polymer and alkyl-modified polysaccharide polymer, and (F2) water phase II containing water
A method for producing an emulsified composition. Step 1 is a step of obtaining a mixed component of an oil phase containing components (A), (B), (C) and an unneutralized component (D), and an aqueous phase containing (F1) and a base in the oil phase. Step 1A comprising a step of mixing I, emulsifying and cooling.
Or the process of obtaining the mixing component of the oil phase containing the salt of component (A), (B), (C) and component (D), and the water phase I containing (F1) in the said oil phase are mixed and emulsified. The method for producing an emulsified composition according to claim 1, wherein the method is Step 1B including a step of cooling.   Step 1 is a step of obtaining a mixed component of an oil phase containing components (A), (B) and (C), and an aqueous phase containing components (D), (F1) and a base that are not neutralized in the oil phase. Step 1C of mixing and emulsifying and cooling I, or a step of obtaining a mixed component of an oil phase containing components (A), (B) and (C), a salt of component (D) and ( The method for producing an emulsified composition according to claim 1, wherein Step 1D comprises a step of mixing, emulsifying and cooling the aqueous phase I containing F1).   The mass proportions of the components (A), (B), (C), (D) and (E) are (E) / ((A) + (B) + (C)) = 0.0025-50, And (E) / (D) = 0.025-100, The manufacturing method of the emulsion composition of any one of Claims 1-3.   The component (A) is one or more compounds selected from glycerin monofatty acid ester, sorbitan monofatty acid ester, sorbitan difatty acid ester, sorbitol monofatty acid ester, sorbitol difatty acid ester, sucrose monofatty acid ester, and glycerin monoalkyl ether. The manufacturing method of the emulsion composition of any one of Claims 1-4.   Component (D) is a fatty acid salt having 12 to 24 carbon atoms, alkyl sulfate ester salt, alkyl ether sulfate salt, fatty acid amide sulfonate, alkyl phosphate, polyoxyethylene alkyl ether phosphate and long chain N-acyl It is chosen from glutamate, The manufacturing method of the emulsion composition of any one of Claims 1-5.   The manufacturing method of the emulsion composition of any one of Claims 1-6 which form (alpha) -gel structure.   The method for producing an emulsified composition according to any one of claims 1 to 7, wherein the emulsified composition has a viscosity at 25 ° C of 10 to 8000 dPas. The following components (A), (B), (C), (D), (E) and (F):
(A) glyceryl monobehenate or monocetyl glyceryl ether 0.001 to 10% by mass,
(B) cetanol or stearyl alcohol 0.001 to 10% by mass,
(C) Ceramides represented by the general formula (2) 0.001 to 15% by mass,

(Wherein R ¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 4 to 30 carbon atoms which may be substituted by a hydroxyl group, a carbonyl group or an amino group; A methylene group, a methine group or an oxygen atom; X ¹ , X ² and X ³ each independently represents a hydrogen atom, a hydroxyl group or an acetoxy group, and X ⁴ represents a hydrogen atom, an acetyl group or a glyceryl group, Combined with the adjacent oxygen atom to form an oxo group (provided that when Z is a methine group, ^one of X ¹ and X ² is a hydrogen atom and the other does not exist. X ⁴ represents an oxo group. When formed, X ³ is not present.); R ² and R ³ each independently represent a hydrogen atom, a hydroxyl group, a hydroxymethyl group or an acetoxymethyl group; R ⁴ represents a hydroxyl group, a carbonyl group or an amino group. Replace A linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 60 carbon atoms which may have an ether bond, an ester bond or an amide bond in the main chain; ⁵ represents a hydrogen atom, or may have a substituent selected from a hydroxyl group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group, and is a linear or branched saturated or unsaturated group having 1 to 30 carbon atoms in total The broken line indicates that it may be an unsaturated bond)
(D) stearoyl glutamate, stearoyl methyl taurate or polyoxyethylene stearyl ether phosphate 0.00025-10 mass%,
(E) (acrylic acid / alkyl acrylate (C10-30)) copolymer, (alkyl acrylate / steareth methacrylate-20) copolymer, laureth-13PG hydroxyethyl cellulose or stearoxy PG hydroxyethyl cellulose sulfonate 0.001-6 mass %,
(F) An emulsified composition containing water. Component (A) is glyceryl monobehenate,
Component (B) is cetanol,
Ceramides in which component (C) is represented by general formula (3) or general formula (4),

(Wherein R ¹¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 7 to 19 carbon atoms which may be substituted by a hydroxyl group; Z ¹ represents a methylene group or a methine group; X ⁵ , X ⁶ and X ⁷ each independently represents a hydrogen atom, a hydroxyl group or an acetoxy group; X ⁸ represents a hydrogen atom or together with an adjacent oxygen atom, forms an oxo group. (However, when Z ¹ is a methine group, ^one of X ⁵ and X ⁶ is a hydrogen atom and the other does not exist. When X ⁸ forms an oxo group, X ⁷ does not exist.); R ¹² represents a hydroxymethyl group or an acetoxymethyl group; R ¹³ represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; R ¹⁴ has 5 to 30 carbon atoms which may be substituted by a hydroxyl group Whether it is a linear, branched or cyclic saturated or unsaturated hydrocarbon group Or a linear or branched saturated or unsaturated fatty acid having 8 to 22 carbon atoms which may be substituted with a hydroxyl group at the ω-terminal of the alkyl group; Indicates that it may be a bond.)

(In the formula, R ¹⁵ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom having 10 to 22 carbon atoms which may be substituted with a hydroxyl group; X ⁹ represents a hydrogen atom; , An acetyl group or a glyceryl group; R ¹⁶ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group having 5 to 22 carbon atoms which may be substituted with a hydroxyl group or an amino group; Or a hydrocarbon group having an ester bond with a linear or branched saturated or unsaturated fatty acid having 8 to 22 carbon atoms which may be substituted with a hydroxyl group at the ω-terminal; R ¹⁷ represents a hydrogen atom; Or a hydroxyl group, a hydroxyalkoxy group, an alkoxy group or an acetoxy group which may be substituted is an alkyl group having 1 to 30 carbon atoms in total.
Component (D) is stearoyl glutamate,
Component (E) is an (acrylic acid / alkyl acrylate (C10-30)) copolymer, (alkyl acrylate / stealeth methacrylate-20) copolymer, laureth-13PG hydroxyethyl cellulose or stearoxy PG hydroxyethyl cellulose sulfonate Na,
The emulsified composition according to claim 9, wherein the component (F) is water.   The mass proportions of the components (A), (B), (C), (D) and (E) are (E) / ((A) + (B) + (C)) = 0.0025-50, The emulsion composition according to claim 9 or 10, wherein (E) / (D) = 0.025 to 100.   The emulsified composition according to any one of claims 9 to 11, wherein an α-gel structure is formed.   The emulsified composition according to any one of claims 9 to 12, which has a viscosity at 25 ° C of 10 to 8000 dPas.