TWI583948B - 具有堆疊的單向接觸墊之面對面式分析測試條 - Google Patents
具有堆疊的單向接觸墊之面對面式分析測試條 Download PDFInfo
- Publication number
- TWI583948B TWI583948B TW102107192A TW102107192A TWI583948B TW I583948 B TWI583948 B TW I583948B TW 102107192 A TW102107192 A TW 102107192A TW 102107192 A TW102107192 A TW 102107192A TW I583948 B TWI583948 B TW I583948B
- Authority
- TW
- Taiwan
- Prior art keywords
- conductive layer
- test strip
- analytical test
- layer
- carrier sheet
- Prior art date
Links
- 238000004458 analytical method Methods 0.000 title claims description 62
- 239000010410 layer Substances 0.000 claims description 167
- 125000006850 spacer group Chemical group 0.000 claims description 30
- 238000012360 testing method Methods 0.000 claims description 25
- 239000011229 interlayer Substances 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 19
- 239000007788 liquid Substances 0.000 claims description 13
- 239000012491 analyte Substances 0.000 claims description 10
- 210000001124 body fluid Anatomy 0.000 claims description 8
- 239000010839 body fluid Substances 0.000 claims description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 7
- 239000008103 glucose Substances 0.000 claims description 7
- 239000008280 blood Substances 0.000 claims description 6
- 210000004369 blood Anatomy 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 6
- 239000012790 adhesive layer Substances 0.000 claims description 3
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 2
- 238000000059 patterning Methods 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 description 7
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 6
- 238000009413 insulation Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 239000004033 plastic Substances 0.000 description 3
- -1 urine Substances 0.000 description 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000000840 electrochemical analysis Methods 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- VWWQXMAJTJZDQX-UYBVJOGSSA-N flavin adenine dinucleotide Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C2=NC(=O)NC(=O)C2=NC2=C1C=C(C)C(C)=C2 VWWQXMAJTJZDQX-UYBVJOGSSA-N 0.000 description 2
- 235000019162 flavin adenine dinucleotide Nutrition 0.000 description 2
- 239000011714 flavin adenine dinucleotide Substances 0.000 description 2
- 229940093632 flavin-adenine dinucleotide Drugs 0.000 description 2
- ITXSHZFXAHDNMK-UHFFFAOYSA-N iron ruthenium Chemical compound [Fe].[Ru] ITXSHZFXAHDNMK-UHFFFAOYSA-N 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- XOLBLPGZBRYERU-UHFFFAOYSA-N tin dioxide Chemical compound O=[Sn]=O XOLBLPGZBRYERU-UHFFFAOYSA-N 0.000 description 2
- 229910001887 tin oxide Inorganic materials 0.000 description 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 1
- VZXTWGWHSMCWGA-UHFFFAOYSA-N 1,3,5-triazine-2,4-diamine Chemical compound NC1=NC=NC(N)=N1 VZXTWGWHSMCWGA-UHFFFAOYSA-N 0.000 description 1
- 150000004057 1,4-benzoquinones Chemical class 0.000 description 1
- 229930024421 Adenine Natural products 0.000 description 1
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 108010020056 Hydrogenase Proteins 0.000 description 1
- 102000004895 Lipoproteins Human genes 0.000 description 1
- 108090001030 Lipoproteins Proteins 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 229960000643 adenine Drugs 0.000 description 1
- 229910052787 antimony Inorganic materials 0.000 description 1
- WATWJIUSRGPENY-UHFFFAOYSA-N antimony atom Chemical compound [Sb] WATWJIUSRGPENY-UHFFFAOYSA-N 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000011111 cardboard Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000002508 contact lithography Methods 0.000 description 1
- 238000003795 desorption Methods 0.000 description 1
- 238000007772 electroless plating Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- YAGKRVSRTSUGEY-UHFFFAOYSA-N ferricyanide Chemical compound [Fe+3].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] YAGKRVSRTSUGEY-UHFFFAOYSA-N 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 238000007646 gravure printing Methods 0.000 description 1
- 229910052738 indium Inorganic materials 0.000 description 1
- APFVFJFRJDLVQX-UHFFFAOYSA-N indium atom Chemical compound [In] APFVFJFRJDLVQX-UHFFFAOYSA-N 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229960002715 nicotine Drugs 0.000 description 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 239000000123 paper Substances 0.000 description 1
- 229960005489 paracetamol Drugs 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 229920005644 polyethylene terephthalate glycol copolymer Polymers 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- MMXZSJMASHPLLR-UHFFFAOYSA-N pyrroloquinoline quinone Chemical compound C12=C(C(O)=O)C=C(C(O)=O)N=C2C(=O)C(=O)C2=C1NC(C(=O)O)=C2 MMXZSJMASHPLLR-UHFFFAOYSA-N 0.000 description 1
- 238000007650 screen-printing Methods 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 238000004544 sputter deposition Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 229910052715 tantalum Inorganic materials 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/410,609 US9217723B2 (en) | 2012-03-02 | 2012-03-02 | Co-facial analytical test strip with stacked unidirectional contact pads |
| US13/585,330 US20130228475A1 (en) | 2012-03-02 | 2012-08-14 | Co-facial analytical test strip with stacked unidirectional contact pads and inert carrier substrate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201350842A TW201350842A (zh) | 2013-12-16 |
| TWI583948B true TWI583948B (zh) | 2017-05-21 |
Family
ID=47780070
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW102107192A TWI583948B (zh) | 2012-03-02 | 2013-03-01 | 具有堆疊的單向接觸墊之面對面式分析測試條 |
| TW102107191A TW201346256A (zh) | 2012-03-02 | 2013-03-01 | 具有堆疊的單向接觸墊及惰性載體基板之共面分析測試條 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW102107191A TW201346256A (zh) | 2012-03-02 | 2013-03-01 | 具有堆疊的單向接觸墊及惰性載體基板之共面分析測試條 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20130228475A1 (enExample) |
| EP (1) | EP2839020A1 (enExample) |
| JP (1) | JP2015508901A (enExample) |
| KR (1) | KR20140137409A (enExample) |
| CN (1) | CN104160036A (enExample) |
| AU (1) | AU2013224847B2 (enExample) |
| CA (1) | CA2865459A1 (enExample) |
| IN (1) | IN2014DN07234A (enExample) |
| RU (1) | RU2014139828A (enExample) |
| TW (2) | TWI583948B (enExample) |
| WO (1) | WO2013128026A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102954989A (zh) * | 2012-11-30 | 2013-03-06 | 北京宏元兴邦科技有限责任公司 | 一种电化学感测试片 |
| US20160091450A1 (en) * | 2014-09-25 | 2016-03-31 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip to determine analyte measurement time based on measured temperature, physical characteristic and estimated analyte value and their temperature compensated values |
| KR20190091569A (ko) * | 2014-12-19 | 2019-08-06 | 에프. 호프만-라 로슈 아게 | 적어도 하나의 분석물을 전기 화학적으로 검출하기 위한 테스트 엘리먼트 |
| TWI601954B (zh) * | 2016-09-09 | 2017-10-11 | 長庚大學 | 電容式感濕元件及其使用方法 |
| CN108469460B (zh) * | 2018-03-09 | 2019-03-29 | 深圳市刷新智能电子有限公司 | 汗液传感器及其制备方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030102213A1 (en) * | 1997-09-12 | 2003-06-05 | Therasense, Inc. | Biosensor |
| EP2138846A1 (en) * | 2008-06-24 | 2009-12-30 | Lifescan, Inc. | Analyte test strip for accepting diverse sample volumes |
| CN101779120A (zh) * | 2007-07-26 | 2010-07-14 | 埃葛梅崔克斯股份有限公司 | 电化学试条 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3528529B2 (ja) * | 1997-07-31 | 2004-05-17 | Ｎｏｋ株式会社 | バイオセンサ |
| JP5215661B2 (ja) * | 2004-05-21 | 2013-06-19 | アガマトリックス インコーポレーテッド | 電気化学的電池、及び電気化学的電池を作成する方法 |
| US7545272B2 (en) * | 2005-02-08 | 2009-06-09 | Therasense, Inc. | RF tag on test strips, test strip vials and boxes |
| DE502006004037D1 (de) * | 2005-12-19 | 2009-07-30 | Roche Diagnostics Gmbh | Sandwichsensor zur ermittlung einer analytkonzentration |
| US8032321B2 (en) * | 2008-07-15 | 2011-10-04 | Bayer Healthcare Llc | Multi-layered biosensor encoding systems |
-
2012
- 2012-08-14 US US13/585,330 patent/US20130228475A1/en not_active Abandoned
-
2013
- 2013-03-01 RU RU2014139828A patent/RU2014139828A/ru not_active Application Discontinuation
- 2013-03-01 IN IN7234DEN2014 patent/IN2014DN07234A/en unknown
- 2013-03-01 TW TW102107192A patent/TWI583948B/zh not_active IP Right Cessation
- 2013-03-01 AU AU2013224847A patent/AU2013224847B2/en not_active Ceased
- 2013-03-01 TW TW102107191A patent/TW201346256A/zh unknown
- 2013-03-01 CA CA2865459A patent/CA2865459A1/en not_active Abandoned
- 2013-03-01 CN CN201380012191.7A patent/CN104160036A/zh active Pending
- 2013-03-01 WO PCT/EP2013/054222 patent/WO2013128026A1/en not_active Ceased
- 2013-03-01 JP JP2014559257A patent/JP2015508901A/ja active Pending
- 2013-03-01 EP EP13707170.0A patent/EP2839020A1/en not_active Withdrawn
- 2013-03-01 KR KR1020147027754A patent/KR20140137409A/ko not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030102213A1 (en) * | 1997-09-12 | 2003-06-05 | Therasense, Inc. | Biosensor |
| CN101779120A (zh) * | 2007-07-26 | 2010-07-14 | 埃葛梅崔克斯股份有限公司 | 电化学试条 |
| EP2138846A1 (en) * | 2008-06-24 | 2009-12-30 | Lifescan, Inc. | Analyte test strip for accepting diverse sample volumes |
Also Published As
| Publication number | Publication date |
|---|---|
| TW201346256A (zh) | 2013-11-16 |
| JP2015508901A (ja) | 2015-03-23 |
| IN2014DN07234A (enExample) | 2015-04-24 |
| RU2014139828A (ru) | 2016-04-20 |
| US20130228475A1 (en) | 2013-09-05 |
| WO2013128026A1 (en) | 2013-09-06 |
| CN104160036A (zh) | 2014-11-19 |
| AU2013224847B2 (en) | 2018-11-15 |
| AU2013224847A1 (en) | 2014-10-16 |
| CA2865459A1 (en) | 2013-09-06 |
| EP2839020A1 (en) | 2015-02-25 |
| KR20140137409A (ko) | 2014-12-02 |
| TW201350842A (zh) | 2013-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |