TWI561239B - Non-irritating ophthalmic povidone-iodine compositions - Google Patents

Non-irritating ophthalmic povidone-iodine compositions

Info

Publication number
TWI561239B
TWI561239B TW099143958A TW99143958A TWI561239B TW I561239 B TWI561239 B TW I561239B TW 099143958 A TW099143958 A TW 099143958A TW 99143958 A TW99143958 A TW 99143958A TW I561239 B TWI561239 B TW I561239B
Authority
TW
Taiwan
Prior art keywords
iodine compositions
povidone
irritating ophthalmic
irritating
ophthalmic povidone
Prior art date
Application number
TW099143958A
Other languages
English (en)
Other versions
TW201143783A (en
Inventor
Bo Liang
Joseph A Capriotti
C Michael Samson
Jason Stein
Michael Weiser
Original Assignee
Foresight Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44305700&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI561239(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Foresight Biotherapeutics Inc filed Critical Foresight Biotherapeutics Inc
Publication of TW201143783A publication Critical patent/TW201143783A/zh
Application granted granted Critical
Publication of TWI561239B publication Critical patent/TWI561239B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW099143958A 2009-12-15 2010-12-15 Non-irritating ophthalmic povidone-iodine compositions TWI561239B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28669709P 2009-12-15 2009-12-15

Publications (2)

Publication Number Publication Date
TW201143783A TW201143783A (en) 2011-12-16
TWI561239B true TWI561239B (en) 2016-12-11

Family

ID=44305700

Family Applications (3)

Application Number Title Priority Date Filing Date
TW099143958A TWI561239B (en) 2009-12-15 2010-12-15 Non-irritating ophthalmic povidone-iodine compositions
TW105103772A TWI618539B (zh) 2009-12-15 2010-12-15 無刺激性眼用聚乙烯吡咯啶酮-碘組成物
TW105132072A TWI620569B (zh) 2009-12-15 2010-12-15 無刺激性眼用聚乙烯吡咯啶酮-碘組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
TW105103772A TWI618539B (zh) 2009-12-15 2010-12-15 無刺激性眼用聚乙烯吡咯啶酮-碘組成物
TW105132072A TWI620569B (zh) 2009-12-15 2010-12-15 無刺激性眼用聚乙烯吡咯啶酮-碘組成物

Country Status (16)

Country Link
US (1) US20130177522A1 (zh)
EP (1) EP2512230A4 (zh)
JP (3) JP2013514373A (zh)
KR (2) KR20190049931A (zh)
CN (2) CN102811610B (zh)
AR (1) AR079479A1 (zh)
AU (1) AU2010339993A1 (zh)
BR (1) BR112012014260A2 (zh)
CA (1) CA2784492C (zh)
CL (1) CL2012001583A1 (zh)
EC (1) ECSP12012037A (zh)
HK (1) HK1211216A1 (zh)
MX (1) MX364441B (zh)
PE (2) PE20121498A1 (zh)
TW (3) TWI561239B (zh)
WO (1) WO2011084473A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI620569B (zh) * 2009-12-15 2018-04-11 遠景生物製藥股份有限公司 無刺激性眼用聚乙烯吡咯啶酮-碘組成物

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US7767217B2 (en) 2006-03-14 2010-08-03 Foresight Biotherapeutics Ophthalmic compositions comprising povidone-iodine
KR101967938B1 (ko) * 2011-05-12 2019-04-10 포어사이트 바이오쎄라퓨틱스, 인코퍼레이티드 스테로이드 또는 비-스테로이드성 소염제를 갖는 안정한 포비돈-요오드 조성물
GB201114725D0 (en) * 2011-08-25 2011-10-12 Altacor Ltd Ophthalmic formulations
TW201808311A (zh) * 2011-09-16 2018-03-16 遠景生物製藥股份有限公司 安定之普維酮-碘組成物
CN102429862B (zh) 2011-11-29 2013-05-01 江苏德达医药科技有限公司 一种聚维酮碘眼用缓释滴眼液
TW201400117A (zh) * 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
JP6161500B2 (ja) * 2012-10-05 2017-07-12 ロート製薬株式会社 ブロムフェナク含有組成物
JP6304475B2 (ja) * 2013-01-31 2018-04-04 ロート製薬株式会社 点眼剤
JP6304474B2 (ja) * 2013-01-31 2018-04-04 ロート製薬株式会社 点眼剤
ES2841434T3 (es) * 2013-02-01 2021-07-08 Allergan Inc Lagrimas artificiales que comprenden hialuronato de sodio y carboximetilcelulosa
WO2014160579A1 (en) * 2013-03-25 2014-10-02 Insite Vision Incorporated Combination anti-inflammatory ophthalmic compositions
WO2014207769A1 (en) 2013-06-27 2014-12-31 Mylan Laboratories Ltd Process for the preparation of nepafenac
US20150064129A1 (en) * 2013-09-04 2015-03-05 Taiwan Biotech Co., Ltd. Wound healing composition
CN103877120B (zh) * 2014-04-02 2017-07-21 程予良 一种膏药
CN107847604B (zh) * 2015-10-25 2020-11-10 艾威药业(珠海)有限公司 眼用原位凝胶处方
JP6255134B1 (ja) * 2016-11-02 2017-12-27 ヴェローチェ・バイオファーマ・エルエルシー 耳炎の治療のための組成物および方法
KR102351816B1 (ko) 2017-04-21 2022-01-17 노바리크 게엠베하 요오드 조성물
CN108853074A (zh) * 2017-05-10 2018-11-23 武汉先路医药科技股份有限公司 一种含有溴芬酸钠水合物的药物水性滴眼液及其制备方法
BR112021005097A2 (pt) * 2018-09-21 2021-06-08 Ps Therapy Ltd. lágrima artificial, lentes de contato e composições de veículos medicinais e métodos de uso dos mesmos
JP2024504980A (ja) * 2021-01-21 2024-02-02 テジュン ファーマシューティカル カンパニー リミテッド 点眼組成物
US20230181625A1 (en) * 2021-12-14 2023-06-15 Harrow Ip, Llc Method and composition for treating infectious conjunctivitis
CN117338787A (zh) * 2023-11-24 2024-01-05 南京恒道医药科技股份有限公司 一种眼用药物组合物及其制备方法

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US20090263345A1 (en) * 2008-01-28 2009-10-22 Foresight Biotherapeutics, Inc. Otic compositions for the treatment of infections of the internal and external ear in mammals
WO2009151619A1 (en) * 2008-06-12 2009-12-17 Foresight Biotherapeutics, Inc. Povidone iodine, a novel alternative preservative for ophthalmic compositions

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CN102429862B (zh) * 2011-11-29 2013-05-01 江苏德达医药科技有限公司 一种聚维酮碘眼用缓释滴眼液

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090263345A1 (en) * 2008-01-28 2009-10-22 Foresight Biotherapeutics, Inc. Otic compositions for the treatment of infections of the internal and external ear in mammals
WO2009151619A1 (en) * 2008-06-12 2009-12-17 Foresight Biotherapeutics, Inc. Povidone iodine, a novel alternative preservative for ophthalmic compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI620569B (zh) * 2009-12-15 2018-04-11 遠景生物製藥股份有限公司 無刺激性眼用聚乙烯吡咯啶酮-碘組成物

Also Published As

Publication number Publication date
NZ751915A (en) 2020-09-25
JP2013514373A (ja) 2013-04-25
CL2012001583A1 (es) 2013-01-11
CA2784492A1 (en) 2011-07-14
TW201717973A (zh) 2017-06-01
EP2512230A1 (en) 2012-10-24
MX2012006881A (es) 2012-07-04
PE20160526A1 (es) 2016-05-29
US20130177522A1 (en) 2013-07-11
TWI620569B (zh) 2018-04-11
KR20120112537A (ko) 2012-10-11
EP2512230A4 (en) 2013-05-22
CN102811610A (zh) 2012-12-05
AR079479A1 (es) 2012-01-25
MX364441B (es) 2019-04-26
JP2016028101A (ja) 2016-02-25
CN102811610B (zh) 2016-05-18
ECSP12012037A (es) 2012-08-31
KR20190049931A (ko) 2019-05-09
CN104906580A (zh) 2015-09-16
BR112012014260A2 (pt) 2015-09-15
CA2784492C (en) 2020-06-30
WO2011084473A1 (en) 2011-07-14
TW201143783A (en) 2011-12-16
AU2010339993A1 (en) 2012-07-26
TW201630614A (zh) 2016-09-01
JP2018030871A (ja) 2018-03-01
HK1211216A1 (zh) 2016-05-20
TWI618539B (zh) 2018-03-21
PE20121498A1 (es) 2012-11-30

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