TWI441648B - Foxp3胜肽疫苗 - Google Patents

Foxp3胜肽疫苗 Download PDF

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Publication number
TWI441648B
TWI441648B TW096149888A TW96149888A TWI441648B TW I441648 B TWI441648 B TW I441648B TW 096149888 A TW096149888 A TW 096149888A TW 96149888 A TW96149888 A TW 96149888A TW I441648 B TWI441648 B TW I441648B
Authority
TW
Taiwan
Prior art keywords
peptide
foxp3
seq
cells
hla
Prior art date
Application number
TW096149888A
Other languages
English (en)
Chinese (zh)
Other versions
TW200835516A (en
Inventor
Takuya Tsunoda
Ryuji Osawa
Original Assignee
Oncotherapy Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncotherapy Science Inc filed Critical Oncotherapy Science Inc
Publication of TW200835516A publication Critical patent/TW200835516A/zh
Application granted granted Critical
Publication of TWI441648B publication Critical patent/TWI441648B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW096149888A 2007-01-03 2007-12-25 Foxp3胜肽疫苗 TWI441648B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87861507P 2007-01-03 2007-01-03
US89647207P 2007-03-22 2007-03-22

Publications (2)

Publication Number Publication Date
TW200835516A TW200835516A (en) 2008-09-01
TWI441648B true TWI441648B (zh) 2014-06-21

Family

ID=39588270

Family Applications (1)

Application Number Title Priority Date Filing Date
TW096149888A TWI441648B (zh) 2007-01-03 2007-12-25 Foxp3胜肽疫苗

Country Status (14)

Country Link
US (1) US8563516B2 (enExample)
EP (2) EP2114987A4 (enExample)
JP (1) JP5339375B2 (enExample)
KR (1) KR20090099075A (enExample)
CN (1) CN101641369B (enExample)
AU (1) AU2007340834B2 (enExample)
BR (1) BRPI0720794A2 (enExample)
CA (1) CA2674365A1 (enExample)
IL (1) IL199622A0 (enExample)
MX (1) MX2009007261A (enExample)
RU (1) RU2473557C2 (enExample)
SG (1) SG177199A1 (enExample)
TW (1) TWI441648B (enExample)
WO (1) WO2008081581A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009050486A2 (en) * 2007-10-19 2009-04-23 The University Of Surrey Peptide manipulators of regulatory t cell activity
CZ2008565A3 (cs) * 2008-09-15 2009-11-18 Vysoká škola chemicko technologická v Praze Príprava monoklonálních protilátek proti FoxP3 proteinu s použitím modifikovaných virum podobných cástic Masonova-Pfizerova opicího viru
KR20110117112A (ko) * 2008-12-24 2011-10-26 온코세라피 사이언스 가부시키가이샤 C1orf59 펩티드 및 이를 포함하는 백신
TWI507204B (zh) * 2009-05-26 2015-11-11 Oncotherapy Science Inc Cdc45l胜肽與含此胜肽之疫苗
US9458447B2 (en) * 2011-08-12 2016-10-04 Oncotherapy Science, Inc. MPHOSPH1 peptides and vaccines including the same
CN102603892B (zh) * 2012-02-22 2013-10-30 尉军 一种肿瘤标志物foxp3抗原多肽及应用
US11505599B2 (en) * 2016-01-14 2022-11-22 Memorial Sloan-Kettering Cancer Center T cell receptor-like antibodies specific for Foxp3-derived peptides
CN111375055B (zh) * 2020-02-20 2021-09-03 陈宛莎 一种2019-nCoV亚单位疫苗组合物及其免疫方法
CN122438694A (zh) * 2023-12-19 2026-07-21 瑞泽恩制药公司 Foxp3肽及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE922436A1 (en) 1991-07-25 1993-01-27 Idec Pharma Corp Induction of cytotoxic t-lymphocyte responses
US7507542B2 (en) 2001-05-08 2009-03-24 Ucb Sa Method for regulating immune function using the FOXP3 protein
EP2267023B1 (en) 2002-09-12 2015-02-11 Oncotherapy Science, Inc. KDR peptides and vaccines comprising the same
GB0417430D0 (en) * 2004-08-05 2004-09-08 Uc3 A novel HPV vaccine comprising peptides from host cell proteins
JP4628208B2 (ja) * 2004-08-10 2011-02-09 オンコセラピー・サイエンス株式会社 Cxadrl1またはgcud1タンパク質を発現する胃癌または結腸直腸癌の治療のためのペプチドワクチン
JP4840866B2 (ja) 2005-01-19 2011-12-21 学校法人慶應義塾 癌ワクチン

Also Published As

Publication number Publication date
EP2114987A1 (en) 2009-11-11
EP2481748A3 (en) 2012-10-24
US8563516B2 (en) 2013-10-22
CN101641369A (zh) 2010-02-03
MX2009007261A (es) 2009-11-11
AU2007340834A1 (en) 2008-07-10
IL199622A0 (en) 2010-04-15
EP2481748A2 (en) 2012-08-01
US20100092501A1 (en) 2010-04-15
CN101641369B (zh) 2014-10-22
RU2009129531A (ru) 2011-02-10
RU2473557C2 (ru) 2013-01-27
TW200835516A (en) 2008-09-01
AU2007340834B2 (en) 2013-02-28
BRPI0720794A2 (pt) 2014-03-11
CA2674365A1 (en) 2008-07-10
JP2010514669A (ja) 2010-05-06
SG177199A1 (en) 2012-01-30
WO2008081581A1 (en) 2008-07-10
JP5339375B2 (ja) 2013-11-13
KR20090099075A (ko) 2009-09-21
EP2114987A4 (en) 2010-07-21

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Legal Events

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MM4A Annulment or lapse of patent due to non-payment of fees