RU2473557C2 - Вакцины на основе пептида foxp3 - Google Patents

Вакцины на основе пептида foxp3 Download PDF

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Publication number
RU2473557C2
RU2473557C2 RU2009129531/10A RU2009129531A RU2473557C2 RU 2473557 C2 RU2473557 C2 RU 2473557C2 RU 2009129531/10 A RU2009129531/10 A RU 2009129531/10A RU 2009129531 A RU2009129531 A RU 2009129531A RU 2473557 C2 RU2473557 C2 RU 2473557C2
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RU
Russia
Prior art keywords
cells
foxp3
peptide
seq
peptides
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RU2009129531/10A
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English (en)
Russian (ru)
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RU2009129531A (ru
Inventor
Такуя Цунода
Рюдзи Осава
Original Assignee
Онкотерапи Сайенс, Инк.
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Publication of RU2009129531A publication Critical patent/RU2009129531A/ru
Application granted granted Critical
Publication of RU2473557C2 publication Critical patent/RU2473557C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2009129531/10A 2007-01-03 2007-12-26 Вакцины на основе пептида foxp3 RU2473557C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US87861507P 2007-01-03 2007-01-03
US60/878,615 2007-01-03
US89647207P 2007-03-22 2007-03-22
US60/896,472 2007-03-22
PCT/JP2007/001466 WO2008081581A1 (en) 2007-01-03 2007-12-26 Foxp3 peptide vaccine

Publications (2)

Publication Number Publication Date
RU2009129531A RU2009129531A (ru) 2011-02-10
RU2473557C2 true RU2473557C2 (ru) 2013-01-27

Family

ID=39588270

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009129531/10A RU2473557C2 (ru) 2007-01-03 2007-12-26 Вакцины на основе пептида foxp3

Country Status (14)

Country Link
US (1) US8563516B2 (enExample)
EP (2) EP2114987A4 (enExample)
JP (1) JP5339375B2 (enExample)
KR (1) KR20090099075A (enExample)
CN (1) CN101641369B (enExample)
AU (1) AU2007340834B2 (enExample)
BR (1) BRPI0720794A2 (enExample)
CA (1) CA2674365A1 (enExample)
IL (1) IL199622A0 (enExample)
MX (1) MX2009007261A (enExample)
RU (1) RU2473557C2 (enExample)
SG (1) SG177199A1 (enExample)
TW (1) TWI441648B (enExample)
WO (1) WO2008081581A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009050486A2 (en) * 2007-10-19 2009-04-23 The University Of Surrey Peptide manipulators of regulatory t cell activity
CZ2008565A3 (cs) * 2008-09-15 2009-11-18 Vysoká škola chemicko technologická v Praze Príprava monoklonálních protilátek proti FoxP3 proteinu s použitím modifikovaných virum podobných cástic Masonova-Pfizerova opicího viru
KR20110117112A (ko) * 2008-12-24 2011-10-26 온코세라피 사이언스 가부시키가이샤 C1orf59 펩티드 및 이를 포함하는 백신
TWI507204B (zh) * 2009-05-26 2015-11-11 Oncotherapy Science Inc Cdc45l胜肽與含此胜肽之疫苗
US9458447B2 (en) * 2011-08-12 2016-10-04 Oncotherapy Science, Inc. MPHOSPH1 peptides and vaccines including the same
CN102603892B (zh) * 2012-02-22 2013-10-30 尉军 一种肿瘤标志物foxp3抗原多肽及应用
US11505599B2 (en) * 2016-01-14 2022-11-22 Memorial Sloan-Kettering Cancer Center T cell receptor-like antibodies specific for Foxp3-derived peptides
CN111375055B (zh) * 2020-02-20 2021-09-03 陈宛莎 一种2019-nCoV亚单位疫苗组合物及其免疫方法
CN122438694A (zh) * 2023-12-19 2026-07-21 瑞泽恩制药公司 Foxp3肽及其用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2129439C1 (ru) * 1991-07-25 1999-04-27 Айдек Фармасьютикалс Корпорейшн Антигенная композиция для индуцирования ответа цитотоксических т-лимфоцитов, способ индуцирования и способ лечения болезни
US20030170648A1 (en) * 2001-05-08 2003-09-11 Darwin Molecular Corporation Method for regulating immune function in primates using the Foxp3 protein
WO2004024766A1 (ja) * 2002-09-12 2004-03-25 Oncotherapy Science, Inc. Kdrペプチド及びこれを含むワクチン

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0417430D0 (en) * 2004-08-05 2004-09-08 Uc3 A novel HPV vaccine comprising peptides from host cell proteins
JP4628208B2 (ja) * 2004-08-10 2011-02-09 オンコセラピー・サイエンス株式会社 Cxadrl1またはgcud1タンパク質を発現する胃癌または結腸直腸癌の治療のためのペプチドワクチン
JP4840866B2 (ja) 2005-01-19 2011-12-21 学校法人慶應義塾 癌ワクチン

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2129439C1 (ru) * 1991-07-25 1999-04-27 Айдек Фармасьютикалс Корпорейшн Антигенная композиция для индуцирования ответа цитотоксических т-лимфоцитов, способ индуцирования и способ лечения болезни
US20030170648A1 (en) * 2001-05-08 2003-09-11 Darwin Molecular Corporation Method for regulating immune function in primates using the Foxp3 protein
WO2004024766A1 (ja) * 2002-09-12 2004-03-25 Oncotherapy Science, Inc. Kdrペプチド及びこれを含むワクチン

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NAIR S. et al., Vaccination against the Forkhead Family Transcription Factor Foxp3. Enhances Tumor Immunity, Cancer Res, 2007, n.67 (1), January 1, 2007. *

Also Published As

Publication number Publication date
EP2114987A1 (en) 2009-11-11
TWI441648B (zh) 2014-06-21
EP2481748A3 (en) 2012-10-24
US8563516B2 (en) 2013-10-22
CN101641369A (zh) 2010-02-03
MX2009007261A (es) 2009-11-11
AU2007340834A1 (en) 2008-07-10
IL199622A0 (en) 2010-04-15
EP2481748A2 (en) 2012-08-01
US20100092501A1 (en) 2010-04-15
CN101641369B (zh) 2014-10-22
RU2009129531A (ru) 2011-02-10
TW200835516A (en) 2008-09-01
AU2007340834B2 (en) 2013-02-28
BRPI0720794A2 (pt) 2014-03-11
CA2674365A1 (en) 2008-07-10
JP2010514669A (ja) 2010-05-06
SG177199A1 (en) 2012-01-30
WO2008081581A1 (en) 2008-07-10
JP5339375B2 (ja) 2013-11-13
KR20090099075A (ko) 2009-09-21
EP2114987A4 (en) 2010-07-21

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20151227