TWI346098B - Linker compound, ligand complex and production method thereof - Google Patents

Linker compound, ligand complex and production method thereof

Info

Publication number
TWI346098B
TWI346098B TW094103908A TW94103908A TWI346098B TW I346098 B TWI346098 B TW I346098B TW 094103908 A TW094103908 A TW 094103908A TW 94103908 A TW94103908 A TW 94103908A TW I346098 B TWI346098 B TW I346098B
Authority
TW
Taiwan
Prior art keywords
production method
ligand complex
linker compound
linker
compound
Prior art date
Application number
TW094103908A
Other languages
English (en)
Other versions
TW200530151A (en
Inventor
Suda Yasuo
Arano Akio
Kusumoto Shoichi
Sobel Michael
Wakao Masahiro
Original Assignee
Japan Science & Tech Agency
Nat Univ Corp Kagoshima
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Science & Tech Agency, Nat Univ Corp Kagoshima filed Critical Japan Science & Tech Agency
Publication of TW200530151A publication Critical patent/TW200530151A/zh
Application granted granted Critical
Publication of TWI346098B publication Critical patent/TWI346098B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
TW094103908A 2004-02-05 2005-02-05 Linker compound, ligand complex and production method thereof TWI346098B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004029562 2004-02-05

Publications (2)

Publication Number Publication Date
TW200530151A TW200530151A (en) 2005-09-16
TWI346098B true TWI346098B (en) 2011-08-01

Family

ID=34835955

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094103908A TWI346098B (en) 2004-02-05 2005-02-05 Linker compound, ligand complex and production method thereof

Country Status (9)

Country Link
US (1) US7838549B2 (zh)
EP (1) EP1731517B1 (zh)
JP (1) JP4628960B2 (zh)
CN (1) CN1918143B (zh)
CA (1) CA2559962C (zh)
DE (1) DE602005024779D1 (zh)
IL (1) IL177220A0 (zh)
TW (1) TWI346098B (zh)
WO (1) WO2005075453A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4800771B2 (ja) * 2004-02-18 2011-10-26 独立行政法人科学技術振興機構 糖鎖リガンド複合体、およびそのリガンド複合体を用いたタンパク質の分析方法
KR100740071B1 (ko) 2006-03-10 2007-07-16 한불화장품주식회사 리포익산 유도체 및 이를 함유한 피부외용제 조성물
CA2591496C (en) 2006-12-18 2014-09-02 Japan Science And Technology Agency Method of measuring interaction between biomaterial and sugar chain, method of evaluating biomaterial in sugar chain selectivity, method of screening biomaterial, method of patterning biomaterials, and kits for performing these methods
US20100273269A1 (en) * 2007-12-04 2010-10-28 Koninklijke Philips Electronics N.V. Method of measuring molecules in a fluid using label particles
KR101100803B1 (ko) * 2009-04-24 2011-12-29 서울과학기술대학교 산학협력단 리포아마이드가 결합된 고분자화합물과 이의 제조방법
EP2992098B1 (en) * 2013-05-01 2019-03-27 Ionis Pharmaceuticals, Inc. Compositions and methods for modulating hbv and ttr expression
WO2017053769A1 (en) 2015-09-25 2017-03-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Triazole derivatives as p2y14 receptor antagonists
JP7023460B2 (ja) 2017-10-26 2022-02-22 国立大学法人 鹿児島大学 Ｔｌｒリガンド固定化ナノ粒子

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3834607B2 (ja) 2000-06-28 2006-10-18 国立大学法人大阪大学 オリゴ糖鎖・フェニレンジアミン複合化合物の製造方法、オリゴ糖鎖集合化用リンカー化合物、リンカー化合物により集合化したオリゴ糖鎖・フェニレンジアミン複合化合物
US6821529B2 (en) * 2001-09-05 2004-11-23 Deanna Jean Nelson Oligo(ethylene glycoll)-terminated 1,2-dithiolanes and their conjugates useful for preparing self-assembled monolayers
JP3847591B2 (ja) * 2001-09-14 2006-11-22 独立行政法人科学技術振興機構 ヘパリン結合性蛋白質解析用リガンドおよび支持体、並びにオリゴ糖鎖の固定化方法
JP4431777B2 (ja) 2001-12-28 2010-03-17 サン電子株式会社 遊技場管理装置
JP3970811B2 (ja) 2002-09-09 2007-09-05 独立行政法人科学技術振興機構 リンカー化合物及びリガンド、並びにそれらの製造方法

Also Published As

Publication number Publication date
TW200530151A (en) 2005-09-16
US20070213523A1 (en) 2007-09-13
EP1731517A1 (en) 2006-12-13
CA2559962A1 (en) 2005-08-18
EP1731517A4 (en) 2007-09-26
US7838549B2 (en) 2010-11-23
IL177220A0 (en) 2006-12-10
JP4628960B2 (ja) 2011-02-09
CN1918143B (zh) 2012-01-11
CN1918143A (zh) 2007-02-21
WO2005075453A9 (ja) 2006-08-31
DE602005024779D1 (de) 2010-12-30
JPWO2005075453A1 (ja) 2007-08-02
WO2005075453A1 (ja) 2005-08-18
EP1731517B1 (en) 2010-11-17
CA2559962C (en) 2011-03-15

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Legal Events

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MM4A Annulment or lapse of patent due to non-payment of fees