TWI345465B - Proteasome inhibitors and methods of using the same - Google Patents

Proteasome inhibitors and methods of using the same Download PDF

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Publication number
TWI345465B
TWI345465B TW93124291A TW93124291A TWI345465B TW I345465 B TWI345465 B TW I345465B TW 93124291 A TW93124291 A TW 93124291A TW 93124291 A TW93124291 A TW 93124291A TW I345465 B TWI345465 B TW I345465B
Authority
TW
Taiwan
Prior art keywords
amino
methylbutyl
hexahydro
carbonyl
imino
Prior art date
Application number
TW93124291A
Other languages
English (en)
Chinese (zh)
Other versions
TW200529810A (en
Inventor
Alberto Bernareggi
Paolo G Cassara
Sankar Chatterjee
Edmondo Ferretti
Mohamed Iqbal
Mclaughlin Patricia A Messina
Ernesto Menta
Ambrogio Oliva
Original Assignee
Cephalon Inc
Sede Secondaria Della Cell Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc, Sede Secondaria Della Cell Therapeutics Inc filed Critical Cephalon Inc
Publication of TW200529810A publication Critical patent/TW200529810A/zh
Application granted granted Critical
Publication of TWI345465B publication Critical patent/TWI345465B/zh

Links

TW93124291A 2003-08-14 2004-08-13 Proteasome inhibitors and methods of using the same TWI345465B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49576403P 2003-08-14 2003-08-14

Publications (2)

Publication Number Publication Date
TW200529810A TW200529810A (en) 2005-09-16
TWI345465B true TWI345465B (en) 2011-07-21

Family

ID=37426112

Family Applications (1)

Application Number Title Priority Date Filing Date
TW93124291A TWI345465B (en) 2003-08-14 2004-08-13 Proteasome inhibitors and methods of using the same

Country Status (7)

Country Link
CN (1) CN1867572B (ru)
AR (2) AR045381A1 (ru)
MY (1) MY162518A (ru)
PE (1) PE20050360A1 (ru)
TW (1) TWI345465B (ru)
UA (1) UA88771C2 (ru)
ZA (1) ZA200601293B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI598352B (zh) * 2008-09-29 2017-09-11 千禧製藥公司 １-胺基-２-環丁基乙酸衍生物

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2178888B1 (en) * 2007-08-06 2012-07-04 Millennium Pharmaceuticals, Inc. Proteasome inhibitors
CN105837608B (zh) * 2007-08-06 2018-06-08 米伦纽姆医药公司 蛋白酶体抑制剂及其组合物和用途
CN102961387B (zh) * 2007-08-06 2016-04-27 米伦纽姆医药公司 蛋白酶体抑制剂
EA201500431A1 (ru) * 2008-06-17 2015-11-30 Милленниум Фармасьютикалз, Инк. Соединения боронатного эфира и его фармацевтические составы
CN101638414B (zh) * 2008-07-30 2014-01-08 江苏先声药物研究有限公司 肽硼酸及其酯类化合物、制备方法及其用途
CN101747354B (zh) * 2008-12-04 2014-08-13 江苏先声药物研究有限公司 一类β氨基酸组成的二肽硼酸及其酯类化合物、制备方法及其用途
CA2785300A1 (en) * 2009-12-22 2011-07-21 Cephalon, Inc. Proteasome inhibitors and processes for their preparation, purification and use
RU2012146101A (ru) * 2010-03-31 2014-05-10 Милленниум Фармасьютикалз, Инк. Производные 1-амино-2-циклопропилэтилбороновой кислоты
SG11201702628XA (en) * 2014-10-01 2017-04-27 Merck Patent Gmbh Boronic acid derivatives
CN106588965A (zh) * 2015-10-15 2017-04-26 北京大学 脲拟肽硼酸化合物及其药物组合物、制备方法和用途
WO2017198194A1 (zh) * 2016-05-19 2017-11-23 成都奥璟生物科技有限公司 一种硼酸和硼酸酯类化合物及其应用
JP7071400B6 (ja) * 2017-01-18 2022-06-07 プリンシピア バイオファーマ インコーポレイテッド 免疫プロテアソーム阻害剤
TW201831191A (zh) * 2017-01-23 2018-09-01 大陸商成都奥璟生物科技有限公司 一種新的硼酸衍生物及其藥物組合物
CN114437119A (zh) * 2020-10-30 2022-05-06 苏州开拓药业股份有限公司 一种c-Myc蛋白抑制剂及其制备方法和用途

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI598352B (zh) * 2008-09-29 2017-09-11 千禧製藥公司 １-胺基-２-環丁基乙酸衍生物

Also Published As

Publication number Publication date
AR095249A2 (es) 2015-09-30
TW200529810A (en) 2005-09-16
PE20050360A1 (es) 2005-06-10
ZA200601293B (en) 2009-09-30
UA88771C2 (ru) 2009-11-25
CN1867572A (zh) 2006-11-22
MY162518A (en) 2017-06-15
CN1867572B (zh) 2012-03-28
AR045381A1 (es) 2005-10-26

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