TWI335217B - Pharmaceutical formulations of modafinil - Google Patents

Pharmaceutical formulations of modafinil Download PDF

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Publication number
TWI335217B
TWI335217B TW092125314A TW92125314A TWI335217B TW I335217 B TWI335217 B TW I335217B TW 092125314 A TW092125314 A TW 092125314A TW 92125314 A TW92125314 A TW 92125314A TW I335217 B TWI335217 B TW I335217B
Authority
TW
Taiwan
Prior art keywords
modafinil
unit
agent
adhd
treatment
Prior art date
Application number
TW092125314A
Other languages
English (en)
Chinese (zh)
Other versions
TW200412934A (en
Inventor
Craig Heacock
Alpa Parikh
Piyush Patel
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32511269&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI335217(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of TW200412934A publication Critical patent/TW200412934A/zh
Application granted granted Critical
Publication of TWI335217B publication Critical patent/TWI335217B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
TW092125314A 2002-09-13 2003-09-15 Pharmaceutical formulations of modafinil TWI335217B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41039502P 2002-09-13 2002-09-13
US10/660,058 US20040116532A1 (en) 2002-09-13 2003-09-11 Pharmaceutical formulations of modafinil

Publications (2)

Publication Number Publication Date
TW200412934A TW200412934A (en) 2004-08-01
TWI335217B true TWI335217B (en) 2011-01-01

Family

ID=32511269

Family Applications (1)

Application Number Title Priority Date Filing Date
TW092125314A TWI335217B (en) 2002-09-13 2003-09-15 Pharmaceutical formulations of modafinil

Country Status (22)

Country Link
US (4) US20040116532A1 (is)
EP (1) EP1539126B1 (is)
JP (1) JP5039246B2 (is)
KR (1) KR101125462B1 (is)
CN (1) CN100528151C (is)
AU (1) AU2003267156B2 (is)
BR (1) BR0314514A (is)
CA (1) CA2498260C (is)
DK (1) DK1539126T3 (is)
EA (1) EA012964B1 (is)
ES (1) ES2392580T3 (is)
HK (1) HK1076734A1 (is)
IL (1) IL167054A (is)
IS (1) IS2871B (is)
MX (1) MXPA05002827A (is)
NO (1) NO333614B1 (is)
NZ (1) NZ538941A (is)
PL (1) PL375833A1 (is)
PT (1) PT1539126E (is)
SI (1) SI1539126T1 (is)
TW (1) TWI335217B (is)
WO (1) WO2004024134A1 (is)

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US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
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US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
US20070066996A1 (en) * 2003-03-17 2007-03-22 Katzman Daniel E Modafinil-based neurorehabilitation of impaired neurological function associated with brian injury
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
AR046410A1 (es) * 2003-09-18 2005-12-07 Cephalon Inc Composiciones farmaceuticas para la liberacion modificada de modafinilo
UA94380C2 (ru) * 2003-09-18 2011-05-10 Сефалон, Інк. Фармацевтические композиции модафинила с модифицированным высвобождением
WO2005099822A2 (en) * 2004-04-13 2005-10-27 Cephalon, Inc. Reduction of drug / drug interactions with modafinil
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US20060024370A1 (en) 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
US20060025420A1 (en) * 2004-07-30 2006-02-02 Boehringer Ingelheimn International GmbH Pharmaceutical compositions for the treatment of female sexual disorders
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JP2009513604A (ja) * 2005-10-29 2009-04-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 月経前障害及び他の女性の性的障害治療用のベンゾイミダゾロン誘導体
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US20070105869A1 (en) * 2005-11-08 2007-05-10 Stephane Pollentier Use of flibanserin for the treatment of pre-menopausal sexual desire disorders
EP1988898A2 (en) * 2006-02-18 2008-11-12 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment of attention deficit hyperactivity disorder comprising flibanserin
EP2037927B1 (en) 2006-06-30 2010-01-27 Boehringer Ingelheim International GmbH Flibanserin for the treatment of urinary incontinence and related diseases
EP2043648A1 (en) * 2006-07-14 2009-04-08 Boehringer Ingelheim International GmbH Use of flibanserin for the treatment of sexual disorders in females
CL2007002214A1 (es) * 2006-08-14 2008-03-07 Boehringer Ingelheim Int Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp
JP5793828B2 (ja) * 2006-08-14 2015-10-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング フリバンセリンの製剤及びその製造方法
EP2056797A2 (en) * 2006-08-25 2009-05-13 Boehringer Ingelheim International GmbH Controlled release system and method for manufacturing the same
US8173169B2 (en) * 2007-07-11 2012-05-08 Hikma Pharmaceuticals Formulation and process for the preparation of modafinil
UY31335A1 (es) * 2007-09-12 2009-04-30 Tratamiento de sintomas vasomotores
FR2987265B1 (fr) * 2012-02-28 2014-02-28 Debregeas Et Associes Pharma Composition pharmaceutique sous forme de sirop a base de modafinil, son procede de fabrication et son application

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Also Published As

Publication number Publication date
US20120316244A1 (en) 2012-12-13
US20080207761A1 (en) 2008-08-28
NO20051079L (no) 2005-03-23
CN1681486A (zh) 2005-10-12
AU2003267156A1 (en) 2004-04-30
EP1539126A1 (en) 2005-06-15
CA2498260C (en) 2014-02-04
EA012964B1 (ru) 2010-02-26
EA200500488A1 (ru) 2005-12-29
US8859621B2 (en) 2014-10-14
WO2004024134A8 (en) 2005-07-21
IL167054A (en) 2011-07-31
EP1539126B1 (en) 2012-08-29
DK1539126T3 (da) 2012-11-19
TW200412934A (en) 2004-08-01
IS7714A (is) 2005-02-24
CA2498260A1 (en) 2004-03-25
KR101125462B1 (ko) 2012-03-28
ES2392580T3 (es) 2012-12-12
US8268892B2 (en) 2012-09-18
JP2006522006A (ja) 2006-09-28
WO2004024134A1 (en) 2004-03-25
NZ538941A (en) 2007-09-28
CN100528151C (zh) 2009-08-19
BR0314514A (pt) 2005-08-09
HK1076734A1 (en) 2006-01-27
AU2003267156B2 (en) 2010-03-11
PT1539126E (pt) 2012-11-14
PL375833A1 (en) 2005-12-12
MXPA05002827A (es) 2005-08-16
IS2871B (is) 2014-03-15
JP5039246B2 (ja) 2012-10-03
US8686047B2 (en) 2014-04-01
US20120322880A1 (en) 2012-12-20
KR20050113163A (ko) 2005-12-01
NO333614B1 (no) 2013-07-22
US20040116532A1 (en) 2004-06-17
SI1539126T1 (sl) 2012-11-30

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