TWI245756B - Improved process for the preparation of 1,3-substituted indenes - Google Patents
Improved process for the preparation of 1,3-substituted indenes Download PDFInfo
- Publication number
- TWI245756B TWI245756B TW092132907A TW92132907A TWI245756B TW I245756 B TWI245756 B TW I245756B TW 092132907 A TW092132907 A TW 092132907A TW 92132907 A TW92132907 A TW 92132907A TW I245756 B TWI245756 B TW I245756B
- Authority
- TW
- Taiwan
- Prior art keywords
- preparation
- improved process
- substituted indenes
- indenes
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/47—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of rings being part of condensed ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Addiction (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Circuit Arrangements For Discharge Lamps (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42902902P | 2002-11-25 | 2002-11-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
TW200413301A TW200413301A (en) | 2004-08-01 |
TWI245756B true TWI245756B (en) | 2005-12-21 |
Family
ID=32393492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW092132907A TWI245756B (en) | 2002-11-25 | 2003-11-24 | Improved process for the preparation of 1,3-substituted indenes |
Country Status (16)
Country | Link |
---|---|
US (1) | US7285686B2 (zh) |
EP (1) | EP1567483A1 (zh) |
JP (1) | JP2006507342A (zh) |
KR (1) | KR100655848B1 (zh) |
CN (1) | CN1714075A (zh) |
AR (1) | AR042205A1 (zh) |
AU (1) | AU2003278510B8 (zh) |
BR (1) | BR0316482A (zh) |
CA (1) | CA2511762A1 (zh) |
MX (1) | MXPA05005517A (zh) |
PL (1) | PL377292A1 (zh) |
RS (1) | RS20050393A (zh) |
RU (1) | RU2284319C2 (zh) |
TW (1) | TWI245756B (zh) |
WO (1) | WO2004048318A1 (zh) |
ZA (1) | ZA200503190B (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2618398A1 (en) | 2005-08-11 | 2007-02-22 | University Of Massachusetts Lowell | Novel methods for forming copolymers comprising olefin and protected or unprotected hydroxystyrene units |
CA2709774C (en) | 2008-05-22 | 2012-10-02 | Teva Pharmaceutical Industries Ltd. | Varenicline tosylate, an intermediate in the preparation process of varenicline l-tartrate |
WO2009155403A2 (en) * | 2008-06-19 | 2009-12-23 | Teva Pharmaceutical Industries Ltd. | Processes for the preparation of varenicline and intermediates thereof |
WO2010005643A1 (en) * | 2008-07-10 | 2010-01-14 | Teva Pharmaceutical Industries Ltd. | Processes for purifying varenicline l-tartrate salt and preparing crystalline forms of varenicline l-tartrate salt |
US8178537B2 (en) | 2009-06-22 | 2012-05-15 | Teva Pharmaceutical Industries Ltd. | Solid state forms of varenicline salts and processes for preparation thereof |
EP3280498A4 (en) * | 2015-04-08 | 2018-10-10 | Kemin Industries, Inc. | Protective action of lutein against blue light on human skin cell lines |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6605610B1 (en) * | 1997-12-31 | 2003-08-12 | Pfizer Inc | Aryl fused azapolycyclic compounds |
US6410550B1 (en) * | 1997-12-31 | 2002-06-25 | Pfizer Inc | Aryl fused azapolycyclic compounds |
AU2002234836B2 (en) * | 2001-04-20 | 2007-08-23 | Pfizer Products Inc. | Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds |
BR0316392A (pt) | 2002-11-20 | 2005-09-27 | Pfizer Prod Inc | Processo para preparar ácido indan-1,3-dicarboxìlico |
US20070066827A1 (en) | 2003-01-15 | 2007-03-22 | Pfizer Inc. | Process for the preparation of aryl fused polycyclic lactams |
-
2003
- 2003-11-12 KR KR1020057009301A patent/KR100655848B1/ko not_active IP Right Cessation
- 2003-11-12 JP JP2004554771A patent/JP2006507342A/ja not_active Withdrawn
- 2003-11-12 MX MXPA05005517A patent/MXPA05005517A/es active IP Right Grant
- 2003-11-12 WO PCT/IB2003/005121 patent/WO2004048318A1/en active Application Filing
- 2003-11-12 EP EP03769810A patent/EP1567483A1/en not_active Withdrawn
- 2003-11-12 AU AU2003278510A patent/AU2003278510B8/en not_active Ceased
- 2003-11-12 RU RU2005115881/04A patent/RU2284319C2/ru active
- 2003-11-12 RS YUP-2005/0393A patent/RS20050393A/sr unknown
- 2003-11-12 CN CNA2003801040364A patent/CN1714075A/zh active Pending
- 2003-11-12 CA CA002511762A patent/CA2511762A1/en not_active Abandoned
- 2003-11-12 BR BR0316482-9A patent/BR0316482A/pt not_active IP Right Cessation
- 2003-11-12 PL PL377292A patent/PL377292A1/pl unknown
- 2003-11-17 US US10/714,735 patent/US7285686B2/en not_active Expired - Fee Related
- 2003-11-24 AR ARP030104329A patent/AR042205A1/es unknown
- 2003-11-24 TW TW092132907A patent/TWI245756B/zh not_active IP Right Cessation
-
2005
- 2005-04-20 ZA ZA200503190A patent/ZA200503190B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2003278510A1 (en) | 2004-06-18 |
TW200413301A (en) | 2004-08-01 |
RS20050393A (en) | 2007-12-31 |
WO2004048318A8 (en) | 2005-05-12 |
KR20050087801A (ko) | 2005-08-31 |
ZA200503190B (en) | 2006-07-26 |
US20050004379A1 (en) | 2005-01-06 |
CA2511762A1 (en) | 2004-06-10 |
AU2003278510B2 (en) | 2008-06-05 |
RU2005115881A (ru) | 2006-02-27 |
BR0316482A (pt) | 2005-10-11 |
CN1714075A (zh) | 2005-12-28 |
WO2004048318A1 (en) | 2004-06-10 |
KR100655848B1 (ko) | 2006-12-11 |
AU2003278510B8 (en) | 2008-07-10 |
US7285686B2 (en) | 2007-10-23 |
MXPA05005517A (es) | 2005-07-25 |
JP2006507342A (ja) | 2006-03-02 |
EP1567483A1 (en) | 2005-08-31 |
AR042205A1 (es) | 2005-06-15 |
RU2284319C2 (ru) | 2006-09-27 |
PL377292A1 (pl) | 2006-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Annulment or lapse of patent due to non-payment of fees |