TW354256B - A pharmaceutical composition for oral consumption in aqueous solution comprising a drug/<beta>-cyclodextrin complex and a pharmaceutically acceptable acid-base couple - Google Patents

A pharmaceutical composition for oral consumption in aqueous solution comprising a drug/<beta>-cyclodextrin complex and a pharmaceutically acceptable acid-base couple

Info

Publication number
TW354256B
TW354256B TW083107332A TW83107332A TW354256B TW 354256 B TW354256 B TW 354256B TW 083107332 A TW083107332 A TW 083107332A TW 83107332 A TW83107332 A TW 83107332A TW 354256 B TW354256 B TW 354256B
Authority
TW
Taiwan
Prior art keywords
drug
beta
pharmaceutically acceptable
aqueous solution
cyclodextrin complex
Prior art date
Application number
TW083107332A
Other languages
English (en)
Inventor
Timothy James Grattan
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of TW354256B publication Critical patent/TW354256B/zh

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
TW083107332A 1993-08-10 1994-08-11 A pharmaceutical composition for oral consumption in aqueous solution comprising a drug/<beta>-cyclodextrin complex and a pharmaceutically acceptable acid-base couple TW354256B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939316580A GB9316580D0 (en) 1993-08-10 1993-08-10 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
TW354256B true TW354256B (en) 1999-03-11

Family

ID=10740244

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083107332A TW354256B (en) 1993-08-10 1994-08-11 A pharmaceutical composition for oral consumption in aqueous solution comprising a drug/<beta>-cyclodextrin complex and a pharmaceutically acceptable acid-base couple

Country Status (9)

Country Link
EP (1) EP0720476A1 (zh)
JP (1) JPH09501421A (zh)
CN (1) CN1112180C (zh)
AU (1) AU688789B2 (zh)
CA (1) CA2169159C (zh)
GB (1) GB9316580D0 (zh)
TW (1) TW354256B (zh)
WO (1) WO1995004528A2 (zh)
ZA (1) ZA945930B (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA959469B (en) * 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
ES2171110B1 (es) * 2000-03-03 2003-06-16 Aplicaciones Farmacodinamicas Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion.
ES2189682B1 (es) * 2001-12-11 2004-04-01 Laboratorios Del Dr. Esteve, S.A. Preparacion bebible que comprende ketoprofeno y su empleo en el tratamiento de procesos que cursan con fiebre, inflamacion y/o dolor, en un colectivo de animales, de forma simultanea.
CZ295151B6 (cs) * 2004-02-20 2005-06-15 I. Q. A., A. S. Stabilní, chuťově přijatelné sirupy obsahující ibuprofen a způsob jejich přípravy
DE602007010254D1 (de) * 2006-03-16 2010-12-16 Novartis Ag Feste dosierungsform mit einem wirkstoff mit unterdrücktem geschmack
KR20170123724A (ko) 2006-03-28 2017-11-08 자블린 파머슈티칼스 인코포레이티드 저 투여량의 디클로페낙 및 베타-사이클로덱스트린 제형
LT2253329T (lt) * 2009-04-27 2017-02-27 Laboratorio De Aplicaciones Farmacodinamicas, S.A. Ibuprofeno lizinato peroralinė suspensija
TW201038296A (en) * 2009-04-27 2010-11-01 Aplicaciones Farmacodinamicas S A Lab De Ibuprofen lysinate oral suspension
JP5853430B2 (ja) * 2010-06-21 2016-02-09 大正製薬株式会社 内服液剤
CN101987089B (zh) * 2010-11-10 2012-07-04 天大药业(珠海)有限公司 泡腾药物制剂
GB201021267D0 (en) * 2010-12-15 2011-01-26 Reckitt Benckiser Healthcare Int Ltd Novel pharmaceutical formulation
NZ702930A (en) * 2012-06-28 2017-05-26 Mcneil-Ppc Inc Racecadotril liquid compositions
US9114171B2 (en) * 2012-06-28 2015-08-25 Mcneil-Ppc, Inc. Racecadotril liquid compositions
BR112015005968A2 (pt) * 2012-09-18 2017-07-04 Mcneil Ppc Inc formas de dosagem orais de liberação prolongada compreendendo partículas derivadas do ácido propiônico com baixo ponto de fusão
CN111116794A (zh) * 2019-12-20 2020-05-08 蚌埠市鑫晟新材料科技有限公司 一种中性造纸用聚合材料的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
DE3440288A1 (de) * 1984-11-05 1986-05-07 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische zubereitung mit einem gehalt an mindestens einer schleimhautreizenden substanz oder dergleichen, insbesondere profen, sowie verfahren zu ihrer herstellung
CA1298290C (en) * 1987-01-09 1992-03-31 Herand M. Markarian Solution ibuprofen complexes, compositions and processes for preparing the same
GB8724763D0 (en) * 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
GB8813682D0 (en) * 1988-06-09 1988-07-13 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
CH677606A5 (zh) * 1988-07-12 1991-06-14 Aesculapius Pharma Sa
DE3838431A1 (de) * 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
IT1227626B (it) * 1988-11-28 1991-04-23 Vectorpharma Int Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione
US5019663A (en) * 1989-04-03 1991-05-28 Mobil Oil Corp. Heat balanced paraffin upgrading with co-fed oxygenate
JPH02279631A (ja) * 1989-04-18 1990-11-15 Yamanouchi Pharmaceut Co Ltd 薬物のシクロデキストリン包接体及びその製造法
CA2009326C (en) * 1989-05-09 1998-01-27 Lawrence J. Daher Aqueous granulation solution and a method of tablet granulation
CA2021548A1 (en) * 1989-09-01 1991-03-02 Ronald Nash Duvall Effervescent cold or sinus allergy medicine composition having reduced sodium content
US5024997A (en) * 1990-06-22 1991-06-18 American Home Products Corporation Palatable ibuprofen solutions
DE4027927A1 (de) * 1990-09-04 1992-03-05 Bayer Ag Brausekomponente und verfahren zu ihrer herstellung
DE4038314A1 (de) * 1990-11-30 1992-06-04 Puetter Medice Chem Pharm Komplexe des aktiven enantiomers des ibuprofens mit cyclodextrin
JP2579251B2 (ja) * 1991-03-12 1997-02-05 ロシェ・コンシューマー・ヘルス・(ワールドワイド)・リミテッド 非発泡性イブプロフェン組成物

Also Published As

Publication number Publication date
GB9316580D0 (en) 1993-09-29
EP0720476A1 (en) 1996-07-10
ZA945930B (en) 1995-04-05
CN1133006A (zh) 1996-10-09
WO1995004528A3 (en) 1995-03-16
CA2169159C (en) 2005-01-25
CN1112180C (zh) 2003-06-25
AU688789B2 (en) 1998-03-19
AU7609994A (en) 1995-02-28
JPH09501421A (ja) 1997-02-10
WO1995004528A2 (en) 1995-02-16
CA2169159A1 (en) 1995-02-16

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees