TW250482B - - Google Patents
Info
- Publication number
- TW250482B TW250482B TW081109861A TW81109861A TW250482B TW 250482 B TW250482 B TW 250482B TW 081109861 A TW081109861 A TW 081109861A TW 81109861 A TW81109861 A TW 81109861A TW 250482 B TW250482 B TW 250482B
- Authority
- TW
- Taiwan
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77610091A | 1991-10-11 | 1991-10-11 | |
| US07/935,050 US5530113A (en) | 1991-10-11 | 1992-08-25 | Anti-endotoxin compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW250482B true TW250482B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1995-07-01 |
Family
ID=25106455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW081109861A TW250482B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1991-10-11 | 1992-12-09 |
Country Status (4)
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5648343A (en) * | 1994-02-28 | 1997-07-15 | The University Of Georgia Research Foundation | Method for treating LPS-mediated disorders |
| US5681824A (en) | 1995-06-05 | 1997-10-28 | Eisai Co., Ltd. | Substituted liposaccharides useful in the treatment and prevention of endotoxemia |
| US6417172B1 (en) * | 1995-06-05 | 2002-07-09 | Eisai Co., Ltd. | Prevention and treatment of pulmonary bacterial infection or symptomatic pulmonary exposure to endotoxin by inhalation of antiendotoxin drugs |
| WO1997011708A1 (en) * | 1995-09-29 | 1997-04-03 | Eisai Research Institute | Method for treating alcoholic liver disease |
| EP0909562B1 (en) * | 1996-07-03 | 2005-06-29 | Eisai Co., Ltd. | Injections containing lipid a analogues and process for the preparation thereof |
| US6444654B1 (en) | 1997-01-21 | 2002-09-03 | Board Of Regents Of University Of Nebraska | Isolated asgal lipopolysaccharides and use of same to inhibit innate immune response |
| US6172220B1 (en) | 1997-01-21 | 2001-01-09 | Board Of Regents Of University Of Nebraska | Isolated algal lipopolysaccharides and use of same to inhibit endotoxin-initiated sepsis |
| DK1007509T3 (da) * | 1997-08-29 | 2004-06-28 | Univ Johns Hopkins | Antimikrobielle forbindelser |
| AU2003200765B2 (en) * | 1997-08-29 | 2007-01-25 | The Johns Hopkins University | Antimicrobial compounds |
| US6713654B1 (en) * | 1997-08-29 | 2004-03-30 | The Johns Hopkins University School Of Medicine | Antimicrobial compounds |
| US6011066A (en) * | 1998-02-02 | 2000-01-04 | Veterans General Hospital-Taipei | Method for treating septic shock |
| ES2291188T3 (es) | 1999-01-14 | 2008-03-01 | EISAI R&D MANAGEMENT CO., LTD. | Utilizacion de e5564 para el tratamiento de la sepsis por infusion intravenosa. |
| US20040006242A1 (en) | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| AU2008202882B2 (en) * | 1999-02-01 | 2011-06-16 | Eisai R & D Management Co., Ltd. | Immunological adjuvant compound |
| JP4959085B2 (ja) * | 2000-02-18 | 2012-06-20 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ミセル |
| WO2002085117A1 (en) * | 2001-04-24 | 2002-10-31 | Eisai Co., Ltd. | Methods and compositions for preventing and treating septic shock and endotoxemia |
| EP2338497A1 (en) | 2001-08-10 | 2011-06-29 | Eisai R&D Management Co., Ltd. | Treatment and prevention of heat shock protein-associated diseases and conditions |
| WO2003106473A1 (ja) * | 2002-06-18 | 2003-12-24 | 三共株式会社 | グルコシルリピッドa1位カルボキシメチル類縁体 |
| RU2389732C2 (ru) | 2003-01-06 | 2010-05-20 | Корикса Корпорейшн | Некоторые аминоалкилглюкозаминидфосфатные производные и их применение |
| US7960522B2 (en) | 2003-01-06 | 2011-06-14 | Corixa Corporation | Certain aminoalkyl glucosaminide phosphate compounds and their use |
| CN101969771A (zh) * | 2006-02-09 | 2011-02-09 | 埃莱文斯可更新科学公司 | 抗微生物组合物、方法和体系 |
| WO2007092632A2 (en) * | 2006-02-09 | 2007-08-16 | Elevance Renawable Sciences, Inc. | Surface coating compositions and methods |
| HUE037808T2 (hu) | 2006-09-26 | 2018-09-28 | Infectious Disease Res Inst | Szintetikus adalékanyagot tartalmazó vakcina kompozíció |
| US20090181078A1 (en) * | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| WO2009035528A2 (en) * | 2007-09-07 | 2009-03-19 | University Of Georgia Research Foundation, Inc. | Synthetic lipid a derivative |
| CA2764374C (en) | 2009-06-05 | 2019-11-19 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants |
| CN102917715B (zh) | 2010-02-16 | 2015-07-01 | Tfk株式会社 | 疾病的预防改善剂、持久力提高剂、抗疲劳剂、以及使用它们的药品和饮食品 |
| EP3632463A1 (en) | 2011-04-08 | 2020-04-08 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
| ES2787455T3 (es) | 2012-05-16 | 2020-10-16 | Immune Design Corp | Vacunas para el VHS-2 |
| BR112015025709A2 (pt) | 2013-04-18 | 2017-07-18 | Immune Design Corp | monoterapia com gla para uso em tratamento de câncer |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| IL276608B2 (en) | 2018-02-12 | 2024-04-01 | Inimmune Corp | Toll-like receptor ligands |
| CN112930184B (zh) | 2018-12-17 | 2024-07-12 | 卫材R&D管理有限公司 | 包含脂质体的配制品 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4495346A (en) * | 1981-03-30 | 1985-01-22 | Wisconsin Alumni Research Foundation | Method of preparing a disaccharide |
| US5057598A (en) * | 1983-05-06 | 1991-10-15 | Centocor, Inc. | Monoclonal antibodies reactive with endotoxin core |
| US4629722A (en) * | 1984-07-12 | 1986-12-16 | Ribi Immunochem Research, Inc. | Method of inhibiting the onset of acute radiation syndrome |
| US4844894A (en) * | 1984-07-12 | 1989-07-04 | Ribi Immunochem Research Inc. | Method of inhibiting the onset of septicemia and endotoxemia |
| US5066794A (en) * | 1984-08-24 | 1991-11-19 | Daiichi Pharmaceutical Co., Ltd. | Process for preparing a disaccharide derivative |
| JPS6153295A (ja) * | 1984-08-24 | 1986-03-17 | Dai Ichi Seiyaku Co Ltd | ジサツカライド誘導体 |
| NL8601551A (nl) * | 1985-06-28 | 1987-01-16 | Sandoz Ag | Nieuwe saccharides, hun bereiding en farmaceutische samenstellingen, die hen bevatten. |
| US4918163A (en) * | 1985-09-27 | 1990-04-17 | Pfizer Inc. | Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria |
| US4877611A (en) * | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
| US4929604A (en) * | 1986-05-28 | 1990-05-29 | Board Of Regents, The University Of Texas System | Lipopolysaccharides of reduced toxicity and the production thereof |
| JP2535048B2 (ja) * | 1988-02-29 | 1996-09-18 | 第一製薬株式会社 | 新規ジサッカライド誘導体及びその塩 |
| ZA881430B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1988-03-02 | 1988-10-28 | ||
| US5134230A (en) * | 1988-03-02 | 1992-07-28 | Daiichi Pharmaceutical Co., Ltd. | 2-Deoxy-2-aminoglucopyranoside derivatives |
| US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5041427A (en) * | 1989-07-21 | 1991-08-20 | Wisconsin Alumni Research Foundation | Lipid A derivatives |
| US5158939A (en) * | 1989-07-21 | 1992-10-27 | Wisconsin Alumni Research Foundation | Method of stimulating the immune systems of animals and compositions useful therefor |
| JPH0655749B2 (ja) * | 1989-09-20 | 1994-07-27 | 日本たばこ産業株式会社 | リピッドａ単糖類縁体 |
| JP2839916B2 (ja) * | 1989-10-20 | 1998-12-24 | 三共株式会社 | リピドａ３位エーテル類縁体 |
| US5158941A (en) * | 1990-06-08 | 1992-10-27 | E. I. Du Pont De Nemours And Company | Lipid A analog as stimulant for production of interleukin-1 in human monocytes and tumor cell growth inhibitor |
| AU660325B2 (en) * | 1991-10-11 | 1995-06-22 | Eisai Co. Ltd. | Anti-endotoxin compounds and related molecules and methods |
-
1992
- 1992-08-25 US US07/935,050 patent/US5530113A/en not_active Expired - Lifetime
- 1992-10-08 ZA ZA927751A patent/ZA927751B/xx unknown
- 1992-10-09 KR KR1019920018710A patent/KR930007942A/ko not_active Ceased
- 1992-12-09 TW TW081109861A patent/TW250482B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| ZA927751B (en) | 1993-06-10 |
| KR930007942A (ko) | 1993-05-20 |
| US5530113A (en) | 1996-06-25 |