TW218353B - - Google Patents

Info

Publication number
TW218353B
TW218353B TW079108866A TW79108866A TW218353B TW 218353 B TW218353 B TW 218353B TW 079108866 A TW079108866 A TW 079108866A TW 79108866 A TW79108866 A TW 79108866A TW 218353 B TW218353 B TW 218353B
Authority
TW
Taiwan
Application number
TW079108866A
Original Assignee
Nippon Oil Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP02241192A external-priority patent/JP3087293B2/ja
Priority claimed from JP2241191A external-priority patent/JP2874309B2/ja
Application filed by Nippon Oil Co Ltd filed Critical Nippon Oil Co Ltd
Application granted granted Critical
Publication of TW218353B publication Critical patent/TW218353B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
TW079108866A 1989-10-19 1990-10-19 TW218353B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP27021589 1989-10-19
JP02241192A JP3087293B2 (ja) 1990-09-13 1990-09-13 糖応答型高分子複合体
JP2241191A JP2874309B2 (ja) 1990-09-13 1990-09-13 糖応答性高分子複合体

Publications (1)

Publication Number Publication Date
TW218353B true TW218353B (zh) 1994-01-01

Family

ID=27332917

Family Applications (1)

Application Number Title Priority Date Filing Date
TW079108866A TW218353B (zh) 1989-10-19 1990-10-19

Country Status (8)

Country Link
US (1) US5478575A (zh)
EP (1) EP0424168B1 (zh)
KR (1) KR930001305B1 (zh)
AU (1) AU628674B2 (zh)
CA (1) CA2027930C (zh)
DE (1) DE69003068T2 (zh)
DK (1) DK0424168T3 (zh)
TW (1) TW218353B (zh)

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US6063370A (en) * 1996-04-05 2000-05-16 The Board Of Trustees Of The University Of Illinois Macromolecular complexes for drug delivery
US5935599A (en) * 1996-10-28 1999-08-10 The Board Of Trustees Of The University Of Illinois Polymer-associated liposomes for drug delivery and method of manufacturing the same
US7316999B2 (en) * 2000-06-02 2008-01-08 Novo Nordisk A/S Glucose dependent release of insulin from glucose sensing insulin derivatives
JP2003535106A (ja) * 2000-06-02 2003-11-25 ノボ ノルディスク アクティーゼルスカブ グルコース検知性インスリン誘導体からの、インスリンのグルコース依存性放出
US6417237B1 (en) 2000-06-08 2002-07-09 The Board Of Trustees Of The University Of Illinois Macromolecular drug complexes and compositions containing the same
KR100431536B1 (ko) * 2001-02-14 2004-05-20 박상규 ｐＨ변화를 이용한 식품 품질 식별표시계
EP1391209A4 (en) * 2001-05-30 2009-12-16 Chugai Pharmaceutical Co Ltd PROTEIN PREPARATION
WO2003048195A2 (en) * 2001-12-02 2003-06-12 Novo Nordisk A/S Glucose dependant release of insulin from glucose sensing insulin derivatives
US7317000B2 (en) 2001-12-02 2008-01-08 Novo Nordisk A/S Glucose-dependent insulins
GB0305587D0 (en) * 2003-03-11 2003-04-16 Smart Holograms Ltd Sensor
US7943713B2 (en) * 2004-07-30 2011-05-17 Basf Aktiengesellschaft Polymeric boronic acid derivatives and their use for papermaking
CA2507121A1 (en) * 2005-05-12 2006-11-12 Le Groupe Lysac Inc. Galactomannan hydrophobic complexes as superabsorbent polymers
GB0519169D0 (en) * 2005-09-21 2005-10-26 Leuven K U Res & Dev Novel anti-viral strategy
ES2553154T3 (es) * 2006-05-09 2015-12-04 Novo Nordisk A/S Derivado de la insulina
EP2049149B1 (en) 2006-07-31 2015-04-15 Novo Nordisk A/S Pegylated extended insulins
PL2074141T3 (pl) * 2006-09-22 2017-02-28 Novo Nordisk A/S Analogi insuliny oporne na proteazę
EP2152245B1 (en) * 2007-04-30 2015-12-02 Novo Nordisk A/S Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
EP2497462A1 (en) * 2007-06-01 2012-09-12 Novo Nordisk A/S Stable non-aqueous pharmaceutical compositions
US9260502B2 (en) * 2008-03-14 2016-02-16 Novo Nordisk A/S Protease-stabilized insulin analogues
US8691759B2 (en) 2008-03-18 2014-04-08 Novo Nordisk A/S Protease stabilized, acylated insulin analogues
JP2012516340A (ja) 2009-01-28 2012-07-19 スマートセルズ・インコーポレイテツド 合成コンジュゲートおよびその使用
EP2391646B1 (en) 2009-01-28 2016-08-10 Smartcells, Inc. Crystalline insulin-conjugates
EA027757B1 (ru) 2009-01-28 2017-08-31 Смартселлз, Инк. Конъюгат для контролируемой доставки инсулина
CA2750223A1 (en) 2009-01-28 2010-08-05 Smartcells, Inc. Exogenously triggered controlled release materials and uses thereof
US8569231B2 (en) 2009-03-20 2013-10-29 Smartcells, Inc. Soluble non-depot insulin conjugates and uses thereof
WO2010107519A1 (en) 2009-03-20 2010-09-23 Smartcells, Inc. Terminally-functionalized conjugates and uses thereof
EP2448962B1 (en) 2009-06-30 2016-10-19 Novo Nordisk A/S Insulin derivatives
US20130157926A1 (en) 2010-06-18 2013-06-20 Johannes Franciscus Joseph Engbersen Boronated polymers
CA2805739A1 (en) 2010-07-28 2012-02-02 Smartcells, Inc. Drug-ligand conjugates, synthesis thereof, and intermediates thereto
JP2013535467A (ja) 2010-07-28 2013-09-12 スマートセルズ・インコーポレイテツド 組換えにより発現されたインスリンポリペプチドおよびその使用
JP2013541500A (ja) 2010-07-28 2013-11-14 スマートセルズ・インコーポレイテツド 組換えレクチン、結合部位修飾レクチンおよびそれらの用途
BR112014025132A2 (pt) 2012-04-11 2017-07-11 Novo Nordisk As formulações de insulina
WO2013168136A1 (en) * 2012-05-11 2013-11-14 Schlumberger Technology B.V. Thickening of fluids
EP2981310B1 (en) 2013-04-05 2017-07-12 Novo Nordisk A/S Dose logging device for a drug delivery device
BR112016007176A2 (pt) 2013-10-04 2018-01-23 Merck Sharp & Dohme conjugado, composição, usos de um conjugado e de uma composição, e, método para tratar um indivíduo que tem diabete
DK3055325T3 (en) 2013-10-07 2018-04-16 Novo Nordisk As New derivative of an insulin analogue
CN105153347B (zh) * 2015-08-11 2017-07-07 台州学院 糖响应的单分散聚合物空心微球的制备方法
RU2731490C2 (ru) * 2015-12-22 2020-09-03 Ром Энд Хаас Компани Способ суспензионной полимеризации капель, распределенных в водной среде
CN110087674B (zh) 2016-12-16 2023-01-03 诺和诺德股份有限公司 含胰岛素的药物组合物
US11096893B2 (en) 2017-06-02 2021-08-24 North Carolina State University Glucose sensitive compositions for drug delivery
CN107556509B (zh) * 2017-08-28 2020-07-14 上海第二工业大学 一种二维光子晶体葡萄糖传感薄膜的制备方法
CN117624207A (zh) 2017-11-09 2024-03-01 诺和诺德股份有限公司 葡萄糖敏感性白蛋白结合衍生物
CN108102004B (zh) * 2018-01-03 2020-02-14 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 一种葡聚糖聚合物、聚合物胶束和药物载体系统
CN110452390B (zh) * 2018-05-03 2021-04-06 清华大学深圳研究生院 一种胰岛素智能给药制剂
EP3586876A1 (en) 2018-06-21 2020-01-01 Gubra ApS Glucose-sensitive peptide hormones
CN113646329A (zh) * 2019-03-29 2021-11-12 诺和诺德股份有限公司 葡萄糖敏感性胰岛素衍生物
CN110483691B (zh) * 2019-09-25 2021-11-09 安徽大学 一种三元共聚物交联剂及其在扩散渗析专用阳离子膜制备中的应用
CN115975224B (zh) * 2023-03-16 2023-08-08 四川大学 一种pH/ROS双响应的组织粘附载药水凝胶及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0110879A1 (en) * 1982-05-26 1984-06-20 The Children's Medical Center Corporation Reporter compounds
IT1173459B (it) * 1984-03-22 1987-06-24 Sirac Spa Resine boroniche stabili ad elevato potere assorbente selettivo
IT1215406B (it) * 1987-04-03 1990-02-08 Sirac Spa Resine boroniche stabili di elevato poytere assorbente selettivo.
IT1215407B (it) * 1987-04-03 1990-02-08 Sirac Spa Resine boroniche di elevato potere assorbente selettivo.

Also Published As

Publication number Publication date
US5478575A (en) 1995-12-26
CA2027930C (en) 1998-06-30
EP0424168B1 (en) 1993-09-01
CA2027930A1 (en) 1991-04-20
AU628674B2 (en) 1992-09-17
KR910007545A (ko) 1991-05-30
DK0424168T3 (da) 1993-12-13
DE69003068T2 (de) 1993-12-16
KR930001305B1 (ko) 1993-02-25
EP0424168A1 (en) 1991-04-24
AU6475490A (en) 1991-07-11
DE69003068D1 (de) 1993-10-07

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