AU2002349295A1 - Glucose dependant release of insulin from glucose sensing insulin derivatives - Google Patents

Glucose dependant release of insulin from glucose sensing insulin derivatives

Info

Publication number
AU2002349295A1
AU2002349295A1 AU2002349295A AU2002349295A AU2002349295A1 AU 2002349295 A1 AU2002349295 A1 AU 2002349295A1 AU 2002349295 A AU2002349295 A AU 2002349295A AU 2002349295 A AU2002349295 A AU 2002349295A AU 2002349295 A1 AU2002349295 A1 AU 2002349295A1
Authority
AU
Australia
Prior art keywords
glucose
insulin
derivatives
dependant release
sensing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002349295A
Other versions
AU2002349295A8 (en
Inventor
Svend Havelund
Thomas Hoeg-Jensen
Jan Markussen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of AU2002349295A8 publication Critical patent/AU2002349295A8/en
Publication of AU2002349295A1 publication Critical patent/AU2002349295A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
AU2002349295A 2001-12-02 2002-12-02 Glucose dependant release of insulin from glucose sensing insulin derivatives Abandoned AU2002349295A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200101784 2001-12-02
DKPA200101784 2001-12-02
US33703301P 2001-12-05 2001-12-05
US60/337,033 2001-12-05
PCT/DK2002/000804 WO2003048195A2 (en) 2001-12-02 2002-12-02 Glucose dependant release of insulin from glucose sensing insulin derivatives

Publications (2)

Publication Number Publication Date
AU2002349295A8 AU2002349295A8 (en) 2003-06-17
AU2002349295A1 true AU2002349295A1 (en) 2003-06-17

Family

ID=26069103

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002349295A Abandoned AU2002349295A1 (en) 2001-12-02 2002-12-02 Glucose dependant release of insulin from glucose sensing insulin derivatives

Country Status (4)

Country Link
EP (1) EP1453860A2 (en)
JP (1) JP2005526009A (en)
AU (1) AU2002349295A1 (en)
WO (1) WO2003048195A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004002534A1 (en) * 2002-06-27 2004-01-08 Novo Nordisk A/S Use of dimethyl sulfone as isotonicity agent
WO2007096431A1 (en) * 2006-02-27 2007-08-30 Novo Nordisk A/S Insulin derivatives
BRPI0717098B8 (en) 2006-09-22 2021-05-25 Novo Nordisk As protease-resistant human insulin analogues, pharmaceutical composition and process for their preparation
JP5496082B2 (en) 2007-04-30 2014-05-21 ノボ・ノルデイスク・エー／エス Method for drying protein composition, dry protein composition, and pharmaceutical composition containing dry protein
EP2254905B1 (en) 2008-03-14 2016-12-14 Novo Nordisk A/S Protease-stabilized insulin analogues
BRPI0910348B1 (en) 2008-03-18 2021-06-29 Novo Nordisk A/S INSULIN STABILIZED IN ACILLED PROTEASE, PHARMACEUTICAL COMPOSITION INCLUDING IT AND ITS USES
MA33064B1 (en) * 2009-01-28 2012-02-01 Smartcells Inc Concomitant drug control management system
EP2448962B1 (en) 2009-06-30 2016-10-19 Novo Nordisk A/S Insulin derivatives
TWI507462B (en) * 2010-01-25 2015-11-11 羅門哈斯電子材料有限公司 Photoresist comprising nitrogen-containing compound
BR112014010139A2 (en) * 2011-10-27 2017-04-25 Univ Case Western Reserve pharmaceutical formulation, method of reducing a patient's blood sugar level and polypeptide
KR20150002777A (en) 2012-04-11 2015-01-07 노보 노르디스크 에이/에스 Insulin formulations
US9867869B2 (en) 2012-12-12 2018-01-16 Massachusetts Institute Of Technology Insulin derivatives for diabetes treatment
WO2014161952A1 (en) 2013-04-05 2014-10-09 Novo Nordisk A/S Dose logging device for a drug delivery device
ES2676065T3 (en) 2013-10-07 2018-07-16 Novo Nordisk A/S New derivative of an insulin analog
AR099569A1 (en) 2014-02-28 2016-08-03 Novo Nordisk As INSULIN DERIVATIVES AND THE MEDICAL USES OF THESE
CN107530405A (en) * 2015-03-13 2018-01-02 卡斯西部储备大学 Insulin analog containing the glycoregulatory comformational switch of grape
MX2018014929A (en) 2016-06-02 2019-08-26 Sanofi Sa Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein.
TW201831504A (en) * 2016-11-21 2018-09-01 美國凱斯西方瑞瑟夫大學 Rapid-acting insulin analogues of enhanced stability
CA3045882A1 (en) 2016-12-05 2018-06-14 North Carolina State University Core-shell microneedle devices and uses thereof
IL300839B2 (en) 2016-12-16 2024-04-01 Novo Nordisk As Insulin containing pharmaceutical compositions
JP7254792B2 (en) 2017-11-09 2023-04-10 ノヴォ ノルディスク アー／エス glucose-sensitive albumin-binding derivative
WO2019106122A1 (en) 2017-12-01 2019-06-06 Sanofi Novel conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein
US20210214412A1 (en) * 2018-04-16 2021-07-15 University Of Utah Research Foundation Glucose-responsive insulin
TW202112397A (en) * 2019-03-29 2021-04-01 丹麥商諾佛．儂迪克股份有限公司 Glucose sensitive insulin derivatives
JP2022543586A (en) * 2019-07-31 2022-10-13 サーマリン インコーポレイテッド Insulin analogues with glucose-regulated conformational switches
WO2021202802A1 (en) * 2020-03-31 2021-10-07 Protomer Technologies Inc. Conjugates for selective responsiveness to vicinal diols
PE20231948A1 (en) * 2020-11-19 2023-12-05 Protomer Tech Inc AROMATIC COMPOUNDS CONTAINING BORON AND INSULIN ANALOGUES
JPWO2022154055A1 (en) * 2021-01-13 2022-07-21

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU628674B2 (en) * 1989-10-19 1992-09-17 Nippon Oil And Fats Company, Limited Polymer complexes of a sugar response type
CA2370302A1 (en) * 1999-04-27 2000-11-02 Benjamin Lee Hughes Insulin crystals for pulmonary administration
EP1290024A1 (en) * 2000-06-02 2003-03-12 Novo Nordisk A/S Glucose dependent release of insulin from glucose sensing insulin derivatives

Also Published As

Publication number Publication date
EP1453860A2 (en) 2004-09-08
AU2002349295A8 (en) 2003-06-17
WO2003048195A3 (en) 2004-03-25
JP2005526009A (en) 2005-09-02
WO2003048195A2 (en) 2003-06-12

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase