TW202515564A - 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途 - Google Patents

戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途 Download PDF

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Publication number
TW202515564A
TW202515564A TW113125691A TW113125691A TW202515564A TW 202515564 A TW202515564 A TW 202515564A TW 113125691 A TW113125691 A TW 113125691A TW 113125691 A TW113125691 A TW 113125691A TW 202515564 A TW202515564 A TW 202515564A
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Taiwan
Prior art keywords
pyrido
hexahydro
dimethoxy
isobutyl
isoquinolin
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TW113125691A
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English (en)
Chinese (zh)
Inventor
克里斯多福 F 歐布萊恩
迪米崔 Ｅ 葛里高力亞迪斯
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美商紐羅克里生物科學有限公司
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Publication of TW202515564A publication Critical patent/TW202515564A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW113125691A 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途 TW202515564A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662429652P 2016-12-02 2016-12-02
US62/429,652 2016-12-02

Publications (1)

Publication Number Publication Date
TW202515564A true TW202515564A (zh) 2025-04-16

Family

ID=60703209

Family Applications (3)

Application Number Title Priority Date Filing Date
TW113125691A TW202515564A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途
TW106142147A TW201827051A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途
TW112107002A TW202345829A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途

Family Applications After (2)

Application Number Title Priority Date Filing Date
TW106142147A TW201827051A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途
TW112107002A TW202345829A (zh) 2016-12-02 2017-12-01 戊苯那嗪（valbenazine）於治療精神分裂症或情感性精神分裂症之用途

Country Status (5)

Country Link
US (2) US20200078352A1 (cg-RX-API-DMAC10.html)
EP (2) EP3548027A1 (cg-RX-API-DMAC10.html)
JP (3) JP2020500875A (cg-RX-API-DMAC10.html)
TW (3) TW202515564A (cg-RX-API-DMAC10.html)
WO (1) WO2018102673A1 (cg-RX-API-DMAC10.html)

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SG11202100303QA (en) 2018-08-15 2021-02-25 Neurocrine Biosciences Inc Methods for the administration of certain vmat2 inhibitors
US10940141B1 (en) 2019-08-23 2021-03-09 Neurocrine Biosciences, Inc. Methods for the administration of certain VMAT2 inhibitors
CN112933055B (zh) * 2021-03-23 2023-01-13 安徽九华华源药业有限公司 帕利哌酮胃滞留片及其制备方法
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Also Published As

Publication number Publication date
EP4400171A3 (en) 2024-09-11
EP4400171A2 (en) 2024-07-17
JP2023015405A (ja) 2023-01-31
JP2025071099A (ja) 2025-05-02
US20200078352A1 (en) 2020-03-12
JP2020500875A (ja) 2020-01-16
US20210113553A1 (en) 2021-04-22
WO2018102673A1 (en) 2018-06-07
TW201827051A (zh) 2018-08-01
EP3548027A1 (en) 2019-10-09
TW202345829A (zh) 2023-12-01

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